Hepatology Research

Papers
(The TQCC of Hepatology Research is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Reply to Letter to the Editor: Regarding the “Hepatitis B surface antigen glycan isomer is a predictor of the development of hepatocellular carcinoma during nucleoside/nucleotide analog therapy”159
Role of PAR1 −506 deletion/insertion polymorphism in primary sclerosing cholangitis105
Immune‐related adverse event detection in liver cancer patients treated with immune checkpoint inhibitors: Nationwide exploratory survey in Japan81
Factors associated with low hepatitis B surface antigen levels in chronic hepatitis B patients treated with nucleot(s)ide analogs62
Reversion of liver cirrhosis after endovascular treatment in Chinese patients with Budd–Chiari syndrome57
Factors associated with portopulmonary hypertension45
Sofosbuvir/velpatasvir and glecaprevir/pibrentasvir: how should we choose among these two latest and probably the last regimens?44
Development and validation of a prognostic model for 90‐day survival in patients with alcohol‐associated cirrhosis and acute decompensation39
Hyperprogressive disease in patients with unresectable hepatocellular carcinoma receiving atezolizumab plus bevacizumab therapy37
Significance of changes in tumor markers in patients treated with durvalumab plus tremelimumab combination therapy as a surrogate marker for tumor response to unresectable hepatocellular carcinoma37
Lenvatinib radiofrequency ablation sequential therapy offers survival benefits for patients with unresectable hepatocellular carcinoma at intermediate stage and the liver reserve of Child–Pugh A categ36
Deceased Donation Disparities in East Asia—A Tale of Two Systems35
Conditional recurrence analysis of intrahepatic cholangiocarcinoma: Changes in recurrence rate and survival after recurrence resection by disease‐free interval35
Prediction of intrahepatic covalently closed circular DNA levels in patients with resolved hepatitis B virus infection: Impact of serum antibody to hepatitis B core antigen titers35
A combination of hepatic encephalopathy and body mass index was associated with the point of no return for improving liver functional reserve after sofosbuvir/velpatasvir treatment in patients with he29
Significance of portal venous blood flow as a factor to determine liver function in patients with decompensated cirrhosis due to hepatitis C virus infection following achievement of sustained viral re27
Combined effect of histological findings and diabetes mellitus on liver‐related events in patients with metabolic dysfunction‐associated steatotic liver disease26
The change from NAFLD to MAFLD expands fatty liver information flow25
The metabolic evaluation of pemafibrate in nonalcoholic fatty liver disease‐related cardiovascular diseases23
Prognostic value of virtual portal pressure gradient response in compensated cirrhotic patients treated with carvedilol23
Transcriptomic and proteomic studies suggest the establishment of advanced zonation‐like profiles in human‐induced pluripotent stem cell‐derived liver sinusoidal endothelial cells and carboxypeptidase22
Continuous Intravenous Infusion of Hepatocyte Growth Factor Promotes the Development of a Fibrolytic Phenotype in Hepatic Macrophages and Stellate Cells in a Rat Model of Bile Duct Ligation21
Significance of the autoantibody assay in predicting the development of immune‐related adverse events in patients receiving atezolizumab plus bevacizumab combination therapy for unresectable hepatocel21
RECAM‐J 2023—Validation and development of the Japanese version of RECAM for the diagnosis of drug‐induced liver injury20
Issue Information20
Issue Information19
Issue Information19
19
18
Molecular biological role of epithelial splicing regulatory protein 1 in intrahepatic cholangiocarcinoma18
Ratio of von Willebrand factor to ADAMTS13 is a useful predictor of esophagogastric varices progression after sustained virologic response in patients with hepatitis C virus‐related liver cirrhosis17
Epidemiology of Fontan‐associated liver disease in Japan: Results from a nationwide survey in 202117
Potential role of Fibrosis‐4 score in hepatocellular carcinoma screening: The Kangbuk Samsung Health Study17
Magnetic resonance imaging‐based risk factors of hepatocellular carcinoma after direct‐acting antiviral therapy: A multicenter observational study17
Impact of genetic polymorphism on personalized diet and exercise program for steatotic liver disease17
What can we create by adding robotic assistance to conventional laparoscopic liver resection?16
Liver abscess after drug‐eluting bead transarterial chemoembolization for hepatic malignant tumors: Clinical features, pathogenesis, and management16
Chronic liver disease questionnaire to manage patients with chronic liver diseases16
Issue Information15
Serial increase and high alpha‐fetoprotein levels predict the development of hepatocellular carcinoma in 6 months15
Efficacy and safety of lenvatinib‐transcatheter arterial chemoembolization sequential therapy for hepatocellular carcinoma within the up‐to‐seven criteria15
15
Anti‐Ro52/TRIM21 autoantibodies predict Sjögren's syndrome in patients with primary biliary cholangitis15
Differential peripheral memory T cell subsets sensitively indicate the severity of nonalcoholic fatty liver disease15
Issue Information15
Measurement of spleen length and two‐dimensional spleen index is comparable to spleen volumetry by computed tomography for predicting esophageal varices14
Treatment algorithm for thrombocytopenia in patients with chronic liver disease undergoing planned invasive procedures14
High fatty liver index is an independent predictor of ischemic heart disease during a 10‐year period in a Japanese population14
Comparison of diagnostic performance between FIB‐4 and NFS in metabolic‐associated fatty liver disease era14
Early diagnosis of hepatic inflammation in Japanese nonalcoholic fatty liver disease patients using 3D MR elastography13
Multicenter retrospective study of stereotactic body radiotherapy for patients with previously untreated initial small hepatocellular carcinoma13
Safety and effectiveness of SARS‐CoV‐2 vaccines for patients with intractable hepatobiliary diseases: A multicenter, questionnaire‐based, cross‐sectional study13
Clinically relevant model of oxaliplatin‐induced sinusoidal obstruction syndrome13
Clinical Practice Guidelines for Hepatocellular Carcinoma: The Japan Society of Hepatology 2021 version (5th JSH‐HCC Guidelines)12
Moderate‐carbohydrate diet without caloric or lipid restriction for Japanese adult patients with nonalcoholic fatty liver disease: A prospective cohort study12
Quantitative evaluation of tumor signal heterogeneity on gadoxetic acid‐enhanced magnetic resonance imaging as a predictor of postoperative survival and antitumor immunity in hepatocellular carcinoma12
Weighted thyroid‐stimulating hormone disturbance in prognosis of hepatitis B virus‐related acute‐on‐chronic liver failure12
Validation of fatty liver index as a predictor of hepatic steatosis in Asian populations: Impact of alcohol consumption and sex12
Grip strength complements performance status in assessing general condition in patients with unresectable hepatocellular carcinoma treated with atezolizumab and bevacizumab12
11
11
Immunovascular microenvironment in relation to prognostic heterogeneity of WNT/β‐catenin‐activated hepatocellular carcinoma11
Impact of muscle volume changes following atezolizumab‐bevacizumab therapy in patients with unresectable hepatocellular carcinoma11
Comparison of modified CEUS LI‐RADS with sonazoid and CT/MRI LI‐RADS for diagnosis of hepatocellular carcinoma11
Utilizing Altmetrics to Track Advancements in Noninvasive Tests for MASLD11
Predictive model containing gene signature and shear wave elastography to predict patient outcomes after Kasai surgery in biliary atresia10
Spleen stiffness in patients with chronic liver disease evaluated by 2‐D shear wave elastography with ultrasound multiparametric imaging10
Comparative analysis of sorafenib and lenvatinib on HepG2 cells and human umbilical vein endothelial cells: Involvement of transforming growth factor‐β signaling in their molecular effects10
Impact of electrical muscle stimulation on serum myostatin level and maintenance of skeletal muscle mass in patients undergoing living‐donor liver transplantation: Single‐center controlled trial10
Sex‐differences in the association of interleukin‐10 and interleukin‐12 variants with the progression of hepatitis B virus infection in Caucasians10
Absence of large portal collateral vessels is associated with spontaneous improvement of cirrhotic portal vein thrombosis10
10
Cost‐effectiveness of hepatitis E virus vaccination strategy10
Significance of furosemide in patients with cirrhosis treated with or without zinc acetate hydrate supplementation10
9
9
Issue Information9
The role of the nervous system in liver diseases9
Metabolic dysfunction‐associated steatotic liver disease is a risk factor for gallstones: A multicenter cohort study9
9
Issue Information9
Clinical outcomes of antithrombin III‐based therapy for patients with portal vein thrombosis: A retrospective, multicenter study9
Pemafibrate for primary biliary cholangitis with dyslipidemia: A proposal of a new treatment from Japan9
Hepatitis C virus eradication by direct‐acting antivirals causes a simultaneous increase in the prevalence of fatty liver and hyper low‐density lipoprotein cholesterolemia without an increase in body 9
Comparison between splenic dispersion slope and splenic shear wave speed on ultrasound elastography for predicting esophageal varices9
Real‐world efficacy of radiomics versus clinical predictors for microvascular invasion in patients with hepatocellular carcinoma: Large cohort study8
Perturbation of Wnt/β‐catenin signaling and sexual dimorphism in non‐alcoholic fatty liver disease8
Refining the predictive utility of aspartate aminotransferase to platelet ratio index in nonalcoholic fatty liver disease patients with COVID‐198
Management of hepatitis B virus (HBV) reactivation in patients with resolved HBV infection based on a highly sensitive HB core‐related antigen assay8
Low syntaxin 17 expression in donor liver is associated with poor graft prognosis in recipients of living donor liver transplantation8
Artificial intelligence/neural network system that accurately diagnoses hepatocellular carcinoma in nonalcoholic steatohepatitis8
Clinical features of chronic hepatitis B patients with lean nonalcoholic fatty liver disease8
Effects of nucleos(t)ide analogs on hepatitis B surface antigen reduction with interferon‐lambda 3 induction in chronic hepatitis B patients8
Hepatic arterial infusion therapy for advanced hepatocellular carcinoma after systemic treatment failure: A treatment dilemma8
Integrated policy of medical expense subsidies and clinical registry for patients with liver cancer and decompensated cirrhosis in Japan8
Diagnostic criteria for acute‐on‐chronic liver failure and related disease conditions in Japan8
Cachexia and Type 2 Diabetes Mellitus Are Independent Factors for Mortality in Patients With Cirrhosis8
Erratum8
Non‐malignant portal vein thrombosis in a cohort of cirrhotic patients: Incidence and risk factors8
Steroid administration for ischemic complications after radiofrequency ablation: A retrospective study8
Automated image analysis of keratin 7 staining can predict disease outcome in primary sclerosing cholangitis8
Metabolic dysfunction‐associated fatty liver disease and liver fibrosis: Prevalence and associated factors in the middle‐aged and older US population8
Recent advances in hepatitis A virus research and clinical practice guidelines for hepatitis A virus infection in Japan8
Cost‐effectiveness analysis of hepatitis E vaccination strategies among patients with chronic hepatitis B in China7
Alanine aminotransferase levels as therapeutic targets after nucleotide/nucleoside analog therapy in patient with chronic hepatitis B7
Issue Information7
The imbalance between NKG2A and NKG2D expression is involved in NK cell immunosuppression and tumor progression of patients with hepatitis B virus‐related hepatocellular carcinoma7
Validation of Japanese indication criteria for deceased donor liver transplantation for hepatocellular carcinoma: Analysis of US national registry data7
7
Etiological changes of liver cirrhosis and hepatocellular carcinoma‐complicated liver cirrhosis in Japan: Updated nationwide survey from 2018 to 20217
Evaluating the liver function of patients with hepatocellular carcinoma7
7
Biomarkers for predicting nucleos(t)ide analogs discontinuation and hepatitis B virus recurrence after drug withdrawal in chronic hepatitis B patients7
Clinical significance of the latency period of abnormal ammonia metabolism in chronic liver disease: Proposal of a new concept7
Issue Information7
Deciphering the dual nature of the Fibrosis‐4 index in predicting hepatocellular carcinoma risk among hepatitis B patients undergoing nucleos(t)ide analog therapy7
Report of the 22nd nationwide follow‐up Survey of Primary Liver Cancer in Japan (2012–2013)7
2‐Step PLT16‐AST44 method: Simplified liver fibrosis detection system in patients with non‐alcoholic fatty liver disease6
Impact of liver fibrosis on the relative abundance of a urease‐positive Streptococcus salivarius group from saliva in patients with chronic liver disease6
6
Efficacy of antiviral therapy for the prevention of mother‐to‐child transmission of hepatitis B virus and the risk of postpartum hepatitis flare after discontinuation of antiviral therapy6
Total bile acids levels as a stratification tool for screening portopulmonary hypertension in patients with decompensated cirrhosis6
6
A nation‐wide medical record database study: Value of hepatitis B surface antigen loss in chronic hepatitis B patients in Japan6
Analysis of non‐severe acute onset autoimmune hepatitis according to the presence of radiological heterogeneity6
Successful second‐line treatment with cabozantinib for hepatocellular carcinoma harboring cytoplasmic mesenchymal–epithelial transition factor amplification6
Changes in alanine aminotransferase and body composition and metabolic factors among individuals receiving medical health checkups6
Dried blood spot‐based host genome analysis technique targeting pathological associations with hepatitis B: Development and clinical application in the Cambodian population6
Cytokine release syndrome following durvalumab and tremelimumab in advanced hepatocellular carcinoma: A case report with cytokine and damage‐associated molecular pattern analysis6
Issue Information6
Metabolic dysfunction‐associated fatty liver disease and nonalcoholic fatty liver disease: Which can better identify the populations with a high risk of cardiovascular disease?6
High expression of autotaxin is associated with poor recurrence‐free survival in cholangiocarcinoma6
Prognostic performance of a two‐step method using the Fibro‐Scope system for metabolic dysfunction‐associated steatotic liver disease6
Predictors associated with a better response to the Japanese aluminum‐free hepatitis A vaccine, Aimmugen®, for people living with HIV6
Association of early bevacizumab interruption with efficacy of atezolizumab plus bevacizumab for advanced hepatocellular carcinoma: A landmark analysis6
Evaluation of diagnostic criteria for mild‐to‐advanced stages of Fontan‐associated liver disease: A nationwide epidemiological survey in Japan6
Disability in perioperative activities of daily living is associated with worse survival outcomes following hepatic resection in patients with intrahepatic cholangiocarcinoma5
Usefulness of the Global Leadership Initiative on Malnutrition criteria to predict sarcopenia and mortality in patients with chronic liver disease5
Adjuvant Transarterial Chemoembolization After Truly Curative Resection Does Not Improve Survival of Patients With Hepatocellular Carcinoma at High Risk of Recurrence: A Target Trial Emulation Study5
Acknowledgments5
Advancing Gene Mutation Analysis Through Post‐Ablation Liver Tumor Biopsy Specimens5
Fibroblast growth factor receptor 2 alterations in intrahepatic cholangiocarcinoma: Prevalence and clinical implications in Asian populations5
A classification model for resectability in hepatocellular carcinoma patients5
Issue Information5
Prevalence of fatty liver and advanced fibrosis by ultrasonography and FibroScan in a general population random sample5
Optimal treatment strategy and prognostic analysis of salvage liver transplantation for patients with early hepatocellular carcinoma recurrence after hepatectomy5
An improved method to assess skeletal muscle mass in patients with liver cirrhosis based on computed tomography images5
Effects of weight loss on metabolic dysfunction‐associated fatty liver disease in Japanese people: Non‐alcoholic fatty liver disease in the Gifu area, longitudinal analysis study5
The new assay type IV collagen 7S (CLEIA) is a useful test to identify progressive fibrosis in chronic liver disease: A study based on magnetic resonance elastography5
Seroprevalence and incidence of hepatitis E virus infection in the general population of Iwate prefecture, Japan: A retrospective cohort study5
Acknowledgment5
Clinical benefits of partial splenic embolization for cancer patients5
Acknowledgment5
Issue Information5
Transarterial chemoembolization combined with lenvatinib versus transarterial chemoembolization combined with sorafenib for unresectable hepatocellular carcinoma: A comparative retrospective study5
Risk of hepatocellular carcinoma after sustained virologic response in hepatitis C virus patients without advanced liver fibrosis5
Developing a feasible classification model for surgical hepatocellular carcinoma: More questions than answers5
Issue Information5
Evidence‐based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 20205
Effect of metabolic dysfunction‐associated fatty liver disease on liver cancer risk in a population with chronic hepatitis B virus infection: A nationwide study5
Microwave Thermosphere Ablation Versus Radiofrequency Ablation in Hepatocellular Carcinoma: Optimizing Treatment Strategies for Tumor Size and Malignancy Grade5
High serum growth differentiation factor 15 is a risk factor for the occurrence of hepatocellular carcinoma in chronic hepatitis B patients treated with nucleos(t)ide analogs5
5
New nomenclature and subclassification of steatotic liver disease and loss of skeletal muscle mass: A longitudinal cohort study5
Safety and efficacy of switching to pemafibrate from bezafibrate in patients with chronic liver disease5
Cachexia is an independent predictor of mortality in patients with cirrhosis5
Pathological significance of intranuclear structures in liver biopsy samples5
The potential of soluble CD14 in discriminating nonalcoholic steatohepatitis from nonalcoholic fatty liver disease5
0.058125019073486