OOIR: Observatory of International Research

Papers

(The H4-Index of Pharmaceutical Biology is 28. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
The complex lipid, SPPCT-800, reduces lung damage, improves pulmonary function and decreases pro-inflammatory cytokines in the murine LPS-induced acute respiratory distress syndrome (ARDS) model	80
Mechanisms of action of Lycium barbarum polysaccharide in protecting against vitiligo mice through modulation of the STAT3-Hsp70-CXCL9/CXCL10 pathway	69
Concanavalin A promotes angiogenesis and proliferation in endothelial cells through the Akt/ERK/Cyclin D1 axis	69
XiaoEr LianHuaQinqGan alleviates viral pneumonia in mice infected by influenza A and respiratory syncytial viruses	59
Flaxseed extract reduces tissue accumulation and enhances urinary excretion of chondroitin sulphate in the rat: a possible new path in substrate reduction therapy for mucopolysaccharidosis	53
Ranunculus ternatus Thunb extract attenuates renal fibrosis of diabetic nephropathy via inhibiting SMYD2	51
C-Phycocyanin prevents acute myocardial infarction-induced oxidative stress, inflammation and cardiac damage	45
Senkyunolide A inhibits the progression of osteoarthritis by inhibiting the NLRP3 signalling pathway	44
Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment	43
Effects of Tiaopi Xiezhuo decoction on constipation and gut dysbiosis in patients with peritoneal dialysis	42
Modified Zhibai Dihuang pill alleviated urinary tract infection induced by extended-spectrum β-lactamase Escherichia coli in rats by regulating biofilm formation	41
Protective effect of omega-3 polyunsaturated fatty acids on sepsis via the AMPK/mTOR pathway	40
Adjuvant potential of Satureja hortensis metabolites with antibiotics against Gram-positive and Gram-negative bacterial strains	39
Lack of pharmacokinetic interaction between derazantinib and naringin in rats	35
Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyrimidines derived from	35
Baicalin suppress the development of polycystic ovary syndrome via regulating the miR-874-3p/FOXO3 and miR-144/FOXO1 axis	35
Suchilactone inhibits the growth of acute myeloid leukaemia by inactivating SHP2	34
Hyaluronic acid-engineered milk extracellular vesicles to target triple negative breast cancer through CD44	34
Antiproliferative activity, cell-cycle arrest, apoptotic induction and LC-HRMS/MS analyses of extracts from two Linum species	33
Tongmai Yangxin pill alleviates myocardial no-reflow by activating GPER to regulate HIF-1α signaling and downstream potassium channels	32
Indigo naturalis as a potential drug in the treatment of ulcerative colitis: a comprehensive review of current evidence	32
Prevention of ulcerative colitis by Huangqin decoction: reducing the intestinal epithelial cell apoptosis rate through the IFN-γ/JAK/ETS signalling pathway	32
Icariin restrains NLRP3 inflammasome-mediated Th2 immune responses and ameliorates atopic dermatitis through modulating a novel lncRNA MALAT1/miR-124-3p axis	31
Isoalantolactone suppresses gallbladder cancer progression via inhibiting the ERK signalling pathway	31
Mechanism of lily bulb and Rehmannia decoction in the treatment of lipopolysaccharide-induced depression-like rats based on metabolomics study and network pharmacology	31

Yiqi Wenyang decoction protects against the development of atherosclerosis by inhibiting vascular inflammation	30
Chaihu Shugan San promotes gastric motility in rats with functional dyspepsia by regulating Drp-1-mediated ICC mitophagy	30
Screening of rosmarinic acid from Salvia miltiorrhizae acting on the novel target TRPC1 based on the ‘homology modelling–virtual screening–molecular docking–affinity ass	28
Advances in Traditional Chinese Medicine research in diabetic kidney disease treatment	28
A triterpene-enriched natural extract from Eucalyptus tereticornis modulates the expression of genes involved in adipogenesis, lipolysis, and extracellular matrix remode	28
Epigallocatechin-3-gallate at the nanoscale: a new strategy for cancer treatment	28