OOIR: Observatory of International Research

Papers

(The TQCC of Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Hippo pathway activation causes multiple lipid derangements in a murine model of cardiomyopathy	80
Phospholipid isotope tracing suggests β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma	55
Modulation of lipid droplet biogenesis by p38 MAPK and caspase-1 in docosahexaenoic acid-induced EA.hy926 endothelial cell apoptosis	53
From worms to humans: Understanding intestinal lipid metabolism via model organisms	45
Transcriptome profiling of differentiating adipose-derived stem cells across species reveals new genes regulating adipogenesis	43
Functionally diverse front-end desaturases are widespread in the phylum Annelida	32
Co-existence of type I fatty acid synthase and polyketide synthase metabolons in Aurantiochytrium SW1 and their implications for lipid biosynthesis	32
The suppression of pancreatic lipase-related protein 2 ameliorates experimental hepatic fibrosis in mice	29
Lipid transport proteins in malaria, from Plasmodium parasites to their hosts	27
Proteomic and lipidomic landscape of the infrapatellar fat pad and its clinical significance in knee osteoarthritis	26
Eicosapentaenoic acid inhibits cholesterol efflux pathways from cholesterol-loaded human THP-1 macrophages by reducing the hydrolysis of cholesteryl esters mediated by carboxylesterase 1	22
The PAH1-encoded phosphatidate phosphatase of Yarrowia lipolytica differentially affects gene expression and lipid biosynthesis	22
Effect of α-ketoglutarate on maternal lipid homeostasis and mitochondrial status perturbed by gestational arsenic exposure	21
Eicosanoid biosynthesizing enzymes in Prototheria	21
Editorial Board	19
Mechanism of preventive effects of exendin-4 and des-fluoro-sitagliptin in a murine model of fructose-induced prediabetes	19
Hydroperoxide bicyclase CYP50918A1 of Plasmodiophora brassicae (Rhizaria, SAR): Detection of novel enzyme of oxylipin biosynthesis	18
Editorial Board	18
Species-specific accumulation of ceramides in cerebrospinal fluid from encephalomyeloradiculoneurpathy patients associated with peripheral complement activation: A pilot study	18
Oleic acid blocks the calcium-activated chloride channel TMEM16A/ANO1	18
Luteolin, as a bidirectional ROS regulator, elevates mouse beige adipocyte browning	18
Editorial Board	18
Dysregulation of lipid metabolism in the liver of Tspo knockout mice	17
Role of sphingolipids in the host-pathogen interaction	17
Calpain-1 is required for abnormality of liver function and metabolism in apolipoprotein E knockout mouse evaluated noninvasively by small animal MRI and PET-CT	16

A phospholipase B from Pseudomonas aeruginosa with activity towards endogenous phospholipids affects biofilm assembly	16
Molecular mechanisms of cytochrome P450-derived epoxy-fatty acids neuroprotection	16
1-Methylnicotinamide promotes hepatic steatosis in mice: A potential mechanism in chronic alcohol-induced fatty liver disease	15
Comprehensive analysis of the composition of the major phospholipids during the asexual life cycle of the filamentous fungus Aspergillus nidulans	14
NAD supplementation improves mitochondrial performance of cardiolipin mutants	14
Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection?	14
Structures and functions of the gut microbial lipidome	14
The influence of IMPDH activity on ciliogenesis and adipogenesis of 3T3-L1 cells while undergoing differentiation	13
Increased obesogenic action of palmitic acid during early stage of adipogenesis	13
Discovery of novel diagnostic biomarkers for Sjögren-Larsson syndrome by untargeted lipidomics	13
Lipid metabolism associated PLPP4 gene drives oncogenic and adipogenic potential in breast cancer cells	13
Advances in lipid research: From bench to bedside	13
Control of ALOX5 expression in monocytic cells using a synthetic riboswitch	13
Liposome of Phlorizin promote the repair of carotid atherosclerosis in rats by regulating inflammation and the Nrf2 signaling pathway	13
Nuclear and chromatin rearrangement associate to epigenome and gene expression changes in a model of in vitro adipogenesis and hypertrophy	12
A methionine-choline-deficient diet induces nonalcoholic steatohepatitis and alters the lipidome, metabolome, and gut microbiome profile in the C57BL/6J mouse	12
Ca2+/calmodulin-dependent protein kinase II inhibition reduces myocardial fatty acid uptake and oxidation after myocardial infarction	12
Hyperoxic recovery impacts on metabolic adaptations induced by hypoxic exercise: A lipidomics approach	11
Phosphoinositide acyl chain diversity: comparative analysis across species and mouse tissues	11
The Sphinx and the egg: Evolutionary enigmas of the (glyco)sphingolipid biosynthetic pathway	11
Lipids uniquely alter rates of insulin aggregation and lower toxicity of amyloid aggregates	11
Dissection of the synthesis of polyunsaturated fatty acids in nematodes and Collembola of the soil fauna	10
The protective role of peroxisome proliferator-activated receptor gamma in lipotoxic podocytes	10
Age-related changes in cardiolipin profile and functional consequences of altered fatty acid supply	10
Recent advances on the physiological and pathophysiological roles of polyunsaturated fatty acids and their biosynthetic pathway	10
Impact of sphingolipids on protein membrane trafficking	10
LIMP-2 deficiency-associated glycolipid abnormalities in mice	10
The intestine-specific homeobox (ISX) modulates β-carotene-dependent regulation of microsomal triglyceride transfer protein (MTP) in a tissue-specific manner	10
Mechanisms of intestinal triacylglycerol synthesis	10
Phosphoinositide and redox dysregulation by the anticancer methylthioadenosine phosphorylase transition state inhibitor	9
Acute joint inflammation induces a sharp increase in the number of synovial fluid EVs and modifies their phospholipid profile	9
Abnormal expression of sphingolipid-metabolizing enzymes in the heart of spontaneously hypertensive rat models	9
Acylserotonins – a new class of plant lipids with antioxidant activity and potential pharmacological applications	9
Acteoside improves adipocyte browning by CDK6-mediated mTORC1-TFEB pathway	9
Vitamin D status alters genes involved in ovarian steroidogenesis in muskrat granulosa cells	9
Cathepsin G-induced malignant progression of MCF-7 cells involves suppression of PAF signaling through induced expression of PAFAH1B2	9
Cytoskeleton regulates lipid droplet fusion and lipid storage by controlling lipid droplet movement	9
Phosphoinositide transport and metabolism at membrane contact sites	9
The effect of perinatal supplementation of DHA on specialized pro-resolving lipid mediators in the brain of offspring	9
Editorial Board	9
Distinct regions of Praja-1 E3 ubiquitin-protein ligase selectively bind to docosahexaenoic acid-containing phosphatidic acid and diacylglycerol kinase δ	9
Chlorogenic acid enhances PPARγ-mediated lipogenesis through preventing Lipin 1 nuclear translocation in Staphylococcus aureus-exposed bovine mammary epithelial cells	9
Type I collagen reduces lipid accumulation during adipogenesis of preadipocytes 3T3-L1 via the YAP-mTOR-autophagy axis	9
TMAO induces pyroptosis of vascular endothelial cells and atherosclerosis in ApoE−/− mice via MBOAT2-mediated endoplasmic reticulum stress	9
Liver X receptor activation mitigates oxysterol-induced dysfunction in fetoplacental endothelial cells	9
Pulmonary surfactant protein SP-C regulates lipid vesicle uptake by alveolar type II cells and macrophages: Role of lipids, palmitoylation, and environment	8
Effect of N-glycosylation on secretion, degradation and lipoprotein distribution of human serum amyloid A4	8
Echinacoside suppresses macrophage lipid accumulation and attenuates atherosclerosis via the MDM2/PPARγ/ABCA1 signaling axis	8
Hypertriglyceridemia impairs HDL functionality, promotes macrophage metabolic activation and exacerbates antigen-induced rheumatoid arthritis in mice which can be reversed by fenofibrate treatment	8
Phosphatidylethanolamine species with n-3 and n-6 fatty acids modulate macrophage lipidome and attenuate responses to LPS stimulation	8

The impact of fasting on adipose tissue metabolism	8
Editorial Board	8
Elaidic acid induced NLRP3 inflammasome activation via ERS-MAPK signaling pathways in Kupffer cells	8
Origin and evolution of yeast carotenoid pathways	8
Aerobic exercise-induced decrease of chemerin improved glucose and lipid metabolism and fatty liver of diabetes mice through key metabolism enzymes and proteins	8
Zebrafish as outgroup model to study evolution of scavenger receptor class B type I functions	7
Identification and expression of bovine Ucp1 variants	7
Futile cycle of β-oxidation and de novo lipogenesis are associated with essential fatty acids depletion in lipoatrophy	7
Oroxylin A ameliorates non-alcoholic fatty liver disease by modulating oxidative stress and ferroptosis through the Nrf2 pathway	7
Sex modulates the diet-induced changes to the plasma lipidome in a rat model of cardiorespiratory fitness	7
GM1 oligosaccharide efficacy against α-synuclein aggregation and toxicity in vitro	7
Characterization of lipid signatures in the plasma and insulin-sensitive tissues of the C57BL/6J mice fed on obesogenic diets	7
Adcy8 deficiency contributes to impaired lipolysis and an increased prevalence of obesity in mice	7
Different effects of Lorenzo's oil components against very long-chain fatty acid-induced endoplasmic reticulum stress in peroxisome-deficient CHO cells	7
Editorial Board	7
Loss of the acyltransferase TMEM68 leads to growth delay and dysregulation of triacylglycerol and glycerophospholipid homeostasis in the mouse brain	7
Glucagon-like peptide-2 mobilization of intestinal lipid does not require canonical enterocyte chylomicron synthetic machinery	7
Editorial Board	7
Cold-induced phosphatidylethanolamine synthesis in liver and brown adipose tissue of mice	7
Enterocyte-specific ATGL overexpression affects intestinal and systemic cholesterol homeostasis	7
Recent advances in carotenoid absorption, distribution, and elimination	7
Editorial Board	7
Editorial Board	7
Altered levels of sphingomyelins, ceramides, glycerophospholipids, and diacylglycerols in thymoma tissues	7
Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis	7
PNPLA-mediated lipid hydrolysis and transacylation – At the intersection of catabolism and anabolism	7
Architecture and function of yeast phosphatidate phosphatase Pah1 domains/regions	7
OTUD7B controls oxLDL uptake by stabilizing Lox-1 in THP-1 and U937 cells	7
How the liver transcriptome and lipid composition influence the progression of nonalcoholic fatty liver disease to hepatocellular carcinoma in a murine model	7
PEX13 is required for thermogenesis of white adipose tissue in cold-exposed mice	6
Cold-sensitive pathway elongates a non-native cis-7-hexadecenoic acid to cis-9-octadecenoic acid in the cyanobacterium Synechocystis sp. PCC 6803	6
N-butylidenephthalide ameliorates high-fat diet-induced obesity in mice and promotes browning through adrenergic response/AMPK activation in mouse beige adipocytes	6
Anti-inflammatory and anti-viral actions of anionic pulmonary surfactant phospholipids	6
Biological action of docosahexaenoic acid in a 3D tissue-engineered psoriatic skin model: Focus on the PPAR signaling pathway	6
Linarin alleviates high-fat diet-induced NAFLD via modulating the PI3K/Akt/mTOR pathway, autophagy, and gut microbiota	6
SCD1 is nutritionally and spatially regulated in the intestine and influences systemic postprandial lipid homeostasis and gut-liver crosstalk	6
Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling	6
Role of ERA protein in enhancing glyceroglycolipid synthesis and phosphate starvation tolerance in Synechococcus elongatus PCC 7942	6
Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets	6
Curcumin inhibits pancreatic steatosis in mice with a high-fat diet through the YAP/p53 pathway and confirmed through ultrasonic imaging	6
Specificity of ABCA7-mediated cell lipid efflux	6
From LAL-D to MASLD: Insights into the role of LAL and Kupffer cells in liver inflammation and lipid metabolism	6
Endogenous synthesis of n−3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle	6
High-density lipoproteins: A promising tool against cancer	6
Dysregulated mitochondrial fission and neurodegeneration proteomic signature in ACSF3-deficient cells	6