OOIR: Observatory of International Research

Papers

(The TQCC of Journal of Bioscience and Bioengineering is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Hapten-labeled fusion-polymerase chain reaction of multiple marker genes for the application of immunochromatographic test	94
Effect of yeast chromosome II aneuploidy on malate production in sake brewing	59
Effects of genome instability of parental CHO cell clones on chromosome number distribution and recombinant protein production in parent-derived subclones	49
Three 4-monosubstituted butyrolactones from a regulatory gene mutant of Streptomyces rochei 7434AN4	46
Metabolomics approach to elucidate the importance of count size in commercial penaeid shrimps: white leg shrimp (Litopenaeus vannamei) and black tiger shrimp (Penaeus monodon)	45
Nitrogen removal and N2O emissions in anammox reactors: Influence of reactor design on process performance and microbial communities	34
Simultaneous production of cellobiose and xylobiose from alkali-treated bagasse using cellulase secreted by Fe-ion-irradiated Trichoderma reesei mutant	33
Effect of humic acid on aerobic denitrification by Achromobacter sp. strain GAD-3	32
Production and evaluation of enzyme-modified cheese adding protease or lipase to improve quality properties	30
Novel promoter of Pseudozyma antarctica exhibits stable glucose-mediated activation and copper-mediated suppression of flanking genes	29
Developing a simple activity test to estimate nitrous oxide production from sewage treatment	29
Combined use of phosphorus containing calcium silicate and phosphate-solubilizing bacterium as a solid biofertilizer for sustainable soybean cultivation	28
Blending of selected yeast extract and peptone for inducible and constitutive protein production in Escherichia coli using the pET system	25
Establishment of a novel cell line, CHO-MK, derived from Chinese hamster ovary tissues for biologics manufacturing	24
Potassium ion leakage impairs thermotolerance in Corynebacterium glutamicum	23
Fermentation of rose residue by Lactiplantibacillus plantarum B7 and Bacillus subtilis natto promotes polyphenol content and beneficial bioactivity	23
Preparation and performance of biocompatible gadolinium polymer as liver-targeting magnetic resonance imaging contrast agent	23
Synergistic effect of glucagon-like peptide-1 analogue liraglutide and ZnO on the antibacterial, hemostatic, and wound healing properties of nanofibrous dressings	23
Environmental factors drive microbial community succession in biofortified wheat Qu and its improvement on the quality of Chinese huangjiu	22
Whole-genome sequence and characterization of a marine red yeast, Rhodosporidium sphaerocarpum GDMCC 60679, featuring the assimilation of ammonia nitrogen	21
Achyranthes bidentate extracts protect the IL-1β-induced osteoarthritis of SW1353 chondrocytes	21
Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform	21
Identification of tryptophanase from Escherichia coli for the synthesis of S-allyl-l-cysteine and related S-substituted cysteine derivatives	21
Triacetic acid lactone production using 2-pyrone synthase expressing Yarrowia lipolytica via targeted gene deletion	21
Chemicals behind the use of Strombus tricornis opercula in traditional sudanese perfumery and medicine	21

Succession of microbial community of the pit mud under the impact of Daqu of Nongxiang Baijiu	20
Aspergillus oryzae strains heterogeneously produce plant polysaccharide degradation-related enzymes	20
Development of Monascus purpureus monacolin K-hyperproducing mutant strains by synchrotron light irradiation and their comparative genome analysis	20
Bioconversion of C20- and C22-polyunsaturated fatty acids into 9S,15S- and 11S,17S-dihydroxy fatty acids by Escherichia coli expressing double-oxygenating 9S-lipoxygenase from Sphingopyxis macrogoltab	20
Drug in adhesive transdermal patch containing antibiotic-loaded solid lipid nanoparticles	20
Aspergillus oryzae FaeA is responsible for the release of ferulic acid, a precursor of off-odor 4-vinylguaiacol in sake brewing	19
Metagenomic profiling of antibiotic resistance genes and their associations with the bacterial community along the Kanda River, an urban river in Japan	19
Effect of sodium metabisulfite treatment and storage condition on metabolic profile of young coconut (Cocos nucifera L.)	19
Longitudinal gut mycobiota changes in Japanese infants during first three years of life	19
Catalytic potential of a fungal indole prenyltransferase toward β-carbolines, harmine and harman, and their prenylation effects on antibacterial activity	19
Application of gas chromatography-mass spectrometry-based metabolomics in food science and technology	19
Establishment of a nitrate-reductase promoter-driven inducible expression system for metabolic engineering in the marine diatom Fistulifera solaris	18
Locus heterogeneity in the mechanism underlying the superior fermentation performances of phylogenetically distant sake yeasts	18
Yeast diversity during the spontaneous fermentation of wine in a winery and in a laboratory using sterilized equipment	18
Effect of hydrothermal treatment on organic matter degradation, phytotoxicity, and microbial communities in model food waste composting	17
Current advancements in systems and synthetic biology studies of Saccharomyces cerevisiae	17
High accumulation of the Man5GlcNAc2 structure by combining N-acetylglucosaminyltransferase I gene suppression and mannosidase I gene overexpression in Nicotiana tabacum SR1	17
Microbial glycosylation of antitubercular agent chlorflavonin	17
Development of a simple cultured cell–anaerobic microbial co-culture system using liquid paraffin	16
Characterization of a molting-related chitinase from a land crab, Chiromantes haematocheir	15
Exosomes for hair growth and regeneration	15
Application of peptide barcoding to obtain high-affinity anti-PD-1 nanobodies	15
Promotion of a green economy with the palm oil industry for biodiversity conservation: A touchstone toward a sustainable bioindustry	15
Insight investigation into the response pattern of microbial assembly succession and volatile profiles during the brewing of sauce-flavor baijiu based on bioaugmentation	14
Galactosylation of cell-surface glycoprotein required for hyphal growth and cell wall integrity in Schizosaccharomyces japonicus	14
One-pot synthesis of fibrillar-shaped functional nanomaterial using microbial transglutaminase	14
High productivity of cellulase and xylanase enzymes in the mycelial-dispersed Pleurotus ostreatus Δpkac2 strain	14
Mechanisms of production and control of acetate esters in yeasts	14
Intraspecific comparison of mitochondrial genomes reveals the evolution in medicinal fungus Ganoderma lingzhi	14
The bio3 mutation in sake yeast leads to changes in organic acid profiles and ester levels but not ethanol production	14
Genomic analysis of Paenibacillus macerans strain I6, which can effectively saccharify oil palm empty fruit bunches under nutrient-free conditions	14
Characterization of the bacterial community structure in traditional Gifu ayu-narezushi (fermented sweetfish)	14
Generation of a plasmid series for rapid sub-cloning and use in various Enterobacteriaceae	13
Effects of vascular endothelial cells on the neurite outgrowth of nerve cells	13
Anti-microbial, anti-oxidant and wound healing capabilities of Aloe vera-incorporated hybrid nanoflowers	13
Optimization of heterologous protein production process using genetically engineered Ogataea minuta toward industrial-scale manufacturing	13
Bacterial removal using liposomes and an anionic adsorber	13
Comparison of a new peak detection function for selecting a phase-appropriate multi-attribute method system	13
Production of GABA-enriched tomato juice by Lactiplantibacillus plantarum KB1253	13
Domain structure and function of α-1,3-glucanase Agl-EK14 from the gram-negative bacterium Flavobacterium sp. EK-14	12
Generation of novel respiratory syncytial virus vaccine candidate antigens that can induce high levels of prefusion-specific antibodies	12
Characterization of unique EDTA-insensitive methylthioalkylmalate synthase from Eutrema japonicum and its potential application in synthetic biology	12
Combinational manipulation of transcription factors, CreA and ClbR, is a viable strategy to improve cellulolytic enzyme production in Aspergillus aculeatus	12
Identification of 2-furanmethanethiol contributing to roast aroma in honkaku shochu and awamori	12
Gel-in-water nanodispersion for potential application in intravenous delivery of anticancer drugs	12
Optimization of bacteriophage propagation in high-yield continuous culture (cellstat) meeting the constraints of industrial manufacturing processes	12
Effects of fatty acid synthase-inhibitors on polyunsaturated fatty acid production in marine diatom Fistulifera solaris JPCC DA0580	11
Sequence features around cleavage sites are highly conserved among different species and a critical determinant for RNA cleavage position across eukaryotes	11
Characteristics of kopyor coconut (Cocos nucifera L.) using sensory analysis and metabolomics-based approach	11
Peptide array screening with anti-GLP-1 monoclonal antibody: Discovery of cysteine-containing DPP-IV inhibitory peptides	11

Effect of S-adenosyl-methionine accumulation on hineka odor in sake brewed with a non-Kyokai yeast	11
Role of low-level alternating current and impedance for enhancing microalgae biomass and lipid production	11
Enhancing intracellular NADPH bioavailability through improving pentose phosphate pathway flux and its application in biocatalysis asymmetric reduction reaction	11
Isolation of aflatoxin biosynthetic inhibitor from Chondrostereum purpureum mushroom culture filtrate	11
Roles of water in improved production of mycelial biomass and lignocellulose-degrading enzymes by water-supply solid-state fermentation of Ganoderma lucidum	11
Identification and characterization of bacteriocin biosynthetic gene clusters found in multiple bacteriocins producing Lactiplantibacillus plantarum PUK6	11
Bioinformatics in bioscience and bioengineering: Recent advances, applications, and perspectives	11
Functionalized peptide hydrogel to generate human insulin-producing cells in vitro	11
Biotransformation-guided purification of a novel glycoside derived from the extracts of Chinese herb Baizhi	11
Topical delivery of gel-in-oil emulsion cocktail with growth factors for the treatment of diabetic pressure ulcers	10
Characterization and application of Lachancea thermotolerans isolates for sake brewing	10
Isolation of arginine deiminase system-deficient mutants of Tetragenococcus halophilus using arginine analog canavanine	10
Isolation and characterization of koji mold (Aspergillus oryzae) from nature in Niigata	10
Highly genomic instability of super-polyploid strains of Saccharomyces cerevisiae	10
Expansion of human mesenchymal stem cells on poly(vinyl alcohol) microcarriers	10
Cell-penetrating activity of a short-chain ε-poly-l-α-lysine	10
Role of bacterial community succession in flavor formation during Sichuan sun vinegar grain (Cupei) fermentation	10
Elucidation of d-allulose recognition mechanism in ketose 3-epimerase	10
Control of carbon dioxide concentration in headspace of multiple flasks using both non-electric bellows pump and shaking incubator	10
Ribonucleoprotein-based CRISPR/Cas9 genome co-editing in Aspergillus luchuensis mut. kawachii	10
Quantification of leuco-indigo in indigo-dye-fermenting suspension by normal pulse voltammetry	10
Recent advances in plant-based bioproduction	10
Enhancing synthesis of ethyl lactate in rice baijiu fermentation by adding recovered granular cells	10
Reduction of the alcohol-stimulative taste of Japanese pot-distilled spirits	10
Overexpression of the DHA1 family, ChlH and ChlK, leads to enhanced dicarboxylic acids production in koji fungi, Aspergillus luchuensis mut. kawachii and Aspergillus oryzae	10
Spatial, temporal, and biotic changes in the natural abundances of stable carbon and nitrogen isotopes in a biological treatment reactor	10
Metabolomics-based investigation of the differences between traditional and modern soy sauce	9
Modeling the sake brewing characteristics of rice from brown rice metabolites	9
In-situ collagen mineralization modulates metastatic properties of breast cancer cells	9
History of hair analysis by mass spectrometry imaging	9
Characterization of entrapment behavior of polyphenols in nanostructured lipid carriers and its effect on their antioxidative activity	9
Functional analysis of a putative type III polyketide synthase from deep-sea sediment metagenome	9
Efficient production and characterization of soluble active human β-1,2-N-acetylglucosaminyltransferase II in bacteria	9
Early-stage transplant responses in miniature-liver implants based on decellularization-recellularization technology	9
Identification and characterization of rabbit scFv antibodies suitable for immuno-affinity separation of recombinant human kynureninase from Escherichia coli cell lysate	9
Efficient yeast breeding using a sake metabolome analysis for a strain evaluation	9
Biomimetic conjugation inspired from pheomelanin via thiol–quinone addition for enzymatic functionalization of fibroin	9
Correction of substitution, deletion, and insertion mutations by 5′-tailed duplexes	9
Characterization of Zymomonas mobilis promoters that are functional in Escherichia coli	9
Controlling the carbon flux between glycolysis and the pentose phosphate pathway via targeted protein degradation in Corynebacterium glutamicum	9
Beneficial effect of optimizing the expression balance of the mevalonate pathway introduced into the mitochondria on terpenoid production in Saccharomyces cerevisiae	9
Ergothioneine production by Corynebacterium glutamicum harboring heterologous biosynthesis pathways	8
Optimization of tyrosol-producing pathway with tyrosine decarboxylase and tyramine oxidase in high-tyrosine-producing Escherichia coli	8
Prediction of antibody production performance change in Chinese hamster ovary cells using morphological profiling	8
Whole-genome draft assemblies of Paracoccus pantotrophus DSM 11073 and Paracoccus sp. AS002: Phylogenetics entails classification as Paracoccus versutus AS002	8
Recent advances in animal cell technologies for industrial and medical applications	8
Construction of a fusion protein consisting of α-1,3-glucan-binding domains and tetrameric red fluorescent protein, which is involved in the aggregation of α-1,3-glucan and inhibition of fungal biofil	8
Biochemical characterization of l-asparagine synthetase from Streptococcus thermophilus and its application in the enzymatic synthesis of β-aspartyl compounds	8
Different traits for cold tolerance of extremely thermophilic Calditerricola strains isolated from mesothermal municipal sewage sludge and its hyperthermal compost	8
Semi-wet methanogen cathode composed of oak white charcoal for developing sustainable microbial fuel cells	8
Analysis of nitrogen source assimilation in industrial strains of Aspergillus oryzae	8
Hydrogen-producing conditions and mutation mechanisms of a highly efficient mutant strain Ethanoligenens harbinense YR-3	8
Optimizing in vitro expression balance of central dogma-related genes using parallel reaction monitoring	8
Expression of His-tagged NADPH-dependent acetoacetyl-CoA reductase in recombinant Escherichia coli BL-21(DE3)	8
Selective and high-yield production of ethyl α-d-glucopyranoside by the α-glucosyl transfer enzyme of Xanthomonas campestris WU-9701 and glucose isomerase	8
Triple gene expressions in yeast, Escherichia coli, and mammalian cells by transferring DNA fragments amplified from a mother yeast expression plasmid	8
Recent advances in single-cell RNA sequencing of bacteria: Techniques, challenges, and applications	8
Expansion of omega-3 polyunsaturated fatty acid metabolism of the oleaginous diatom Fistulifera solaris by genetic engineering	7
Expression of heterochromatin protein 1 affects citric acid production in Aspergillus luchuensis mut. kawachii	7
Silica adsorption tag derived from the silica polycondensation protein glassin for the immobilization of soluble proteins	7
Decolorization of cationic dyes under alkaline conditions by Iodidimonas sp. Q-1 multicopper oxidase	7
Wide distribution of extracellular electron transfer functionality in natural proteinaceous organic materials for microbial reductive dehalogenation	7
Zein/Fucoidan microcarriers promote myogenic differentiation via topographical cues and hydrodynamic modulation	7
Superior high-efficiency and high-throughput volatile flavor extraction of Japanese fermented seasonings by solvent-assisted stir bar solid extraction with reverse extraction	7
Sterilizable autoantigen immobilized column platform for broad-spectrum removal of pathogenic autoantibodies in autoimmune diseases	7
Gene identification and enzymatic characterization of the initial enzyme in pyrimidine oxidative metabolism, uracil-thymine dehydrogenase	7
Identification of Cyclocybe erebia metabolites that affect the circadian rhythm of Eluc expression under control of Bmal1 promoter in mouse fibroblast cells	7
Profiling volatile compounds from culture supernatants of periodontal bacteria using gas chromatography/mass spectrometry/olfactometry analysis with a monolithic silica gel adsorption device	7
Production of fucoxanthin using a water surface-floating microalga Chromophyton sp. (Hikarimo)	7
Key media microsupplements for boosting de novo lipogenesis in an oleaginic yeast isolate	7
Corrigendum to “Early detection of leptospirosis using Anti-LipL32 carbon nanotube immunofluorescence probe” [J. Biosci. Bioeng. 130 (4) (2020) 424–430]	7
Discovery of long-chain polyamines embedded in the biosilica on the Bacillus cereus spore coat	7
Corrigendum to ‘Metabolomic insight into the synergistic mechanism of action of a bacterial consortium in plant growth promotion’ [J. Biosci. Bioeng. 134 (5) (2022) 399–406]	7
Development of a method for quantifying metabolites in Escherichia coli colonies using hyperspectral imaging	7
Thermostability enhancement of l-glutamate oxidase from Streptomyces sp. NT1 by full consensus protein design	7