Current Protein & Peptide Science

Article	Citations
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	44
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	42
Revolutionizing Infertility Management through Novel Peptide-based Targets	36
Outdoor Allergens of Regional Importance in Asia	28
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	27
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	25
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	24
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	22
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	21
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	21
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	20
Lipidation & Stapled Peptides: Enhancing Stability and Pharmacokinetics	19
2026: The Year of Innovation, Sustainability, and Education in Protein and Peptide Science	18
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	17
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	17
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	16
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	16
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	15
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	14
From Bugs to Benefits: Edible Insects as Exceptional Protein Sources	14
Oak Pollen Allergy in Korea	12
Aminated Polyrotaxanes as Next-Generation Excipients: Dual Roles in Stabilization and Drug Delivery of Injectable Biologics	12
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	12
Versatility of Collagen as a Natural Biopolymer for Biomedical, Food, and Cosmetic Applications	12
A Review on the Pathophysiology of Alzheimer’s Disease	11

Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	11
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	11
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	11
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	11
Herbs and their Active Constituents for Gastric Cancer and Related Problems - Preclinical and Clinical Studies	10
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	10
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	10
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	10
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	9
How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	9
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	8
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	8
Research Progress on the Intervention of Traditional Chinese Medicine Monomers on Signaling Pathways Related to Sarcopenia and Osteoporosis	8
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	8
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	8
Trehalose and its Diverse Biological Potential	8
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	8
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	8
Understanding the Role of NRF2 Signalling in Cancer	8
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Hypoxia A Typical Target in Human Lung Cancer Therapy	7
The Fulcrum of Demyelination in Multiple Sclerosis	7
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	7
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	7
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	7
Birch Pollen Allergens	7
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	7
Profilin and Its Isoforms: Unravelling the Functional Diversity Across Life Forms	6
Biological Significance of EphB4 Expression in Cancer	6
Interaction of Nanomaterials with Protein-Peptide	6
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	6
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	6
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	6
Protein Folding, Aggregation, and Liquid-Liquid Phase Separation	6
Global Trends in Hepatocellular Carcinoma and TGF-β Researc h: A Bibliometric and Visualization Analysis from 2000 to 2024	6
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	6
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	6
Plant bZIP Proteins: Potential use in Agriculture - A Review	6
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	6
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	6
Artificial Intelligence in Proteins and Peptides: A Comprehensive Overview from Hybrid Modeling to Deep Learning	6
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	6
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	6
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	6
Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	6
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	6
Targeting Drug-Resistant Tuberculosis with Antimicrobial Peptides: Opportunities and Challenges	5
Calprotectin: The Link Between Acute Lung Injury and Gastrointestinal Injury in Covid-19: Ban or Boon	5
Comprehensive Analysis of Glycosyltransferase-Related Genes Reveals their Prognostic and Therapeutic Implications in Stomach Adenocarcinoma	5
Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	5

Evolution of Immunotherapy Against Pollen Allergy	5
The Role of Mitochondrial Ion Channels in the Evolution of Anticancer Drug Resistance	5
Molecular Characterization, Expression and In Situ Hybridization Analysis of a Pedal Peptide/Orcokinin-type Neuropeptide in Cuttlefish Sepiella japonica	5
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	5
Cell Surface Markers and their Targeted Drugs in Breast Cancer	5
PI3K/AKT Signaling as a Molecular Link Between Obesity and Female Infertility	5
Bioconjugation Techniques for Enhancing Stability and Targeting Efficiency of Protein and Peptide Therapeutics	5
Antimicrobial Peptides: Structure, Mechanisms, and Therapeutic Potential in Combating Infectious Diseases	5
Spectroscopic Analysis of the Effect of Ibuprofen Degradation Products on the Interaction between Ibuprofen and Human Serum Albumin	5
Preface	5
Multi-omics Analysis Reveals the Role of lncRNAs and Peptides in the Age-related Hearing Loss	5
To Fold, Unfold, or Aggregate: The Induced Coaggregation Mechanism of Amyloidogenic Antimicrobial Peptides for Combating Bacterial Communities	5
Solid-Phase Synthesized Imunofan Confers Clinically Relevant Protection using a Chimeric Protein Vaccine Candidate Against E. coli O157:H7 in BALB/c Mice	5
Post-translational Modification that Shines in the Age of Viruses: ISGylation from a Structural Perspective	4
Enzymatic Targets in the Anticancer Drug Discovery	4
PAK1 Inhibition Suppresses the Proliferation, Migration and Invasion of Glioma Cells	4
Unfolded Protein Response Signaling in Hepatic Stem Cell Activation in Liver Fibrosis	4
Tight Junctions in the Auditory System: Structure, Distribution and Function	4
Use of CRISPR in Infection Control	4
Caspase-3 Activators as Anticancer Agents	4
Acknowledgements to Reviewers	4
Network Pharmacology and Experiments to Verify the Effect andPotential Mechanism of Baicalein on Osteoporosis	4
Soluble Factors Associated with Denervation-induced Skeletal Muscle Atrophy	4
Unveiling the Advances in Protein Kinase: From Concept to Clinic	4
Molecular Players at the Sorting Stations of Malaria Parasite ‘Plasmodium falciparum’	4
Potential of Angiotensin-(1-7) in COVID-19 Treatment	4
Bioactive Pentacyclic Triterpenes Trigger Multiple Signalling Pathways for Selective Apoptosis Leading to Anticancer Efficacy: Recent Updates and Future Perspectives	4
Carboxylic Group Functionalized Carbon Quantum Dots inhibit Hen Egg White Lysozyme Amyloidogenesis, leading to the Formation of Spherical Aggregates with Reduced Toxicity and ROS Generation	4
Genomic Analysis of the Caleosin Family in Theaceae Reveals Lineagespecific Evolutionary Patterns	4
Diabetic Wound: Pathophysiology, Complications and Treatment Strategies	4
An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target	4
Targeting and Modulation of the Natriuretic Peptide System in Covid-19: A Single or Double-Edged Effect?	4
Dynamics of Ubiquitination in Differentiation and Dedifferentiation of Pancreatic β-cells: Putative Target for Diabetes	3
Enzymatic Characterization of Alkaline Protease from a Novel Microorganism Isolated from a Halophilic Environment	3
Messenger RNA Nanomedicine: Innovations and Future Directions	3
The Roles of IGF-1 and MGF on Nerve Regeneration under Hypoxia- Ischemia, Inflammation, Oxidative Stress, and Physical Trauma	3
Aquatic BPI/LBPs: A Promising Antimicrobial Peptide Resource for Disease Control in Aquaculture	3
Discovery of Sulfanilamide-diazo Derivatives Incorporating Benzoic Acid Moieties as Novel Inhibitors of Human Carbonic Anhydrase II Activity	3
Advances in Migraine Treatment: A Comprehensive Clinical Review	3
Investigating the Mechanical Properties and Flexibility of N-BAR Domains in PICK1 by Molecular Dynamics Simulations	3
Comprehensive Overview of Treponema pallidum Outer Membrane Proteins	3
Preface	3
Emerging Role of Non-collagenous Bone Proteins as Osteokines in Extraosseous Tissues	3
Phosphate Toxicity and Vascular Calcification in Chronic Kidney Disease: A Closer Look Utilizing Transmission Electron Microscopy	3
Plant SUT Sucrose Transporters: Structure, Evolution and Biological Functions	3
Human Paraoxonase 1: From Bloodstream Enzyme to Disease Fighter & Therapeutic Intervention	3
Advances in the Study of Noncoding RNAs in the Pathogenesis of Pregnancy-related Diseases	3
Recent Advancement in Novel Wound Healing Therapies by Using Antimicrobial Peptides Derived from Humans and Amphibians	3
Intricacies of PKB/Akt Activity after Sciatic Nerve Damage: A Comprehensive Review	3
Targeting Cdc42: Novel Approaches in Cardiovascular Disorders	3
Molecular Signaling and Biased Agonism of the CHEMR23 Receptor: Implications for Inflammation Resolution and Bone Remodeling	3
Vitamin D: A Repurposed Anti-inflammatory Drug at the Cardiovascular Level	3
MTA1: A Vital Modulator in Prostate Cancer	3
Therapeutic Horizons for Parkinson’s Disease: Current Relevance of PNA5 in Memory and Cognition	3
Insights into the Binding of Metadoxine with Bovine Serum Albumin: A Multi-Spectroscopic Investigation Combined with Molecular Docking	3
The Production, Properties, and Potential Food Applications of Proteins and Peptides from Marine Sources and their Structure-Function Relationship	3
Research Progress of Pectin Methylesterase and its Inhibitors	3
A Perspective on the Impact of Advanced Glycation End Products in the Progression of Diabetic Nephropathy	3
TLR4 Targeting: A Promising Therapeutic Approach Across Multiple Human Diseases	3
The Role of Sirtuins in Diabetic Nephropathy: A Comprehensive Review	2
Peroxisome Biogenesis and Proliferation During Stress	2
Dominant Circulating Cell-free Mycobacterial Proteins in In-use Machining Fluid and their Antigenicity Potential	2
Design of Multitarget Inhibitors as Tracheal Smooth Muscle Relaxants	2
Bile Acids as Signaling Molecules: Role of Ursodeoxycholic Acid in Cholestatic Liver Disease	2
Demystifying Bacteriocins of Human Microbiota by Genome Guided Prospects: An Impetus to Rekindle the Antimicrobial Research	2
Micelles-based Drug Delivery Systems: Implication, Challenges and Future Perspectives in Lung Cancer Therapy	2
Inhibitors of Type II NADH Dehydrogenase Enzyme: A Review	2
A Valuable Target for Therapy: The Metalloproteinase ADAM10	2
Reduced Level of Prolylhydroxyproline in the Nail Clippings of Oral Cancer Patients and its Role as an Activator of Phospholipase C-β2	2
The Role of Various Autoantibodies and Alpha2-Macroglobulin in Patients with Hashimoto Disease: Does the Presence of Elevated AntibodiesCorrelate with Alpha 2-Macroglobulin Levels in Hashimoto Disease	2
Circulating SFRP2 in Iranian Polycystic Ovarian Syndrome Patients with Infertility and Recurrent Pregnancy Loss and its Correlation with Insulin Resistance and Inflammation	2
Insight of Intestinal Fatty Acid Binding Protein as a Potential Biomarker in the Biology of Epithelial Damage of Gastrointestinal Membrane	2
Lethal Yellow Mutation Causes Anxiety, Obsessive-compulsive Behavior and Affects the Brain Melanocortin System in Males and Females of Mice	2
MmpS5-MmpL5 Transporters Deliver M. tuberculosis Resistance to Bedaquiline (BDQ) and Delamanid (DLM)	2
T-Box Transcription Factor 2 Enhances Chemoresistance of Endometrial Cancer by Mediating NRF2 Expression	2
Utilization of Bioactive Silk Protein in the Development of Optical Devices: Recent Advancements and Applications	2
Protein Misfolding and Aggregation of Pathological IgG Light Chains in Oncohematological Dyscrasias: From Molecular Pathways to Clinical Implications	2
Evaluation of Novel HLM Peptide Activity and Toxicity against Planktonic and Biofilm Bacteria: Comparison to Standard Antibiotics	2
RGD Peptide-Based Hydrogel Enhances the Osteogenic Differentiation of Periodontal Ligament Stem Cells via Wnt Signaling	2
Cysteine Peptidases of Calotropis procera (Apocynaceae): A Literature Review on their Biochemical Properties and Potential Applications	2

Utilizing AfDesign for Developing a Small Molecule Inhibitor of PICK- 1-PDZ	2
Pt(IV) Prodrug Photoactivation: A Promising Strategy for Cancer Therapy	2
BH3 Mimetic Peptides: An Effective Strategy to Complement Anticancer Therapy	2
Immuno-informatic Prediction of B and T cell Epitopes of Cysteine Protease Allergen from Phaseolus vulgaris with Cross-reactive Potential and Population Coverage	2
Neuropeptide Y Receptor Modulators in Gut Physiology and Therapy	2