OOIR: Observatory of International Research

Papers

(The TQCC of Current Protein & Peptide Science is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Withdrawal Notice: Overview of Enzyme Engineering Towards the Production of Hyaluronic Acid with Tailored Molecular Weight	28
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	27
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	27
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	22
Outdoor Allergens of Regional Importance in Asia	21
Revolutionizing Infertility Management through Novel Peptide-based Targets	21
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	20
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	18
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	17
Review of post-translational modification of human serum albumin	17
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	17
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	15
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	15
Unveiling the Role of DPYS: A New Prognostic Biomarker in Sarcoma	15
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	15
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	14
From Bugs to Benefits: Edible Insects as Exceptional Protein Sources	13
Structure and Function of the Important Internalins of Listeria monocytogenes	13
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	12
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	11
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	11
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	11
Nanoparticles: A Promising Tool to Promote Reactive Oxygen Species in Cancer Therapy	10
In Silico and In vitro Analysis of Phenolic Acids for Identification of Potential DHFR Inhibitors as Antimicrobial and Anticancer Agents	10
Deciphering the Role of S-adenosyl Homocysteine Nucleosidase in Quorum Sensing Mediated Biofilm Formation	10

Oak Pollen Allergy in Korea	10
Diverse Role of SNARE Protein GS28 in Vesicle Trafficking and Diseases	9
Glycation of Immunoglobulin-G from Pentose Sugar: A Cause for Structural Perturbations	9
Herbs and their Active Constituents for Gastric Cancer and Related Problems - Preclinical and Clinical Studies	8
Structural Analysis of the Interaction between Bcl-xL and the Noncanonical BH3 Domain of Non-Bcl-2 Family Proteins	8
Anti-Platelet Peptides Targeting αIIbβ3 Outside-In Signaling Pathway	8
Small-Molecule Inhibitors Targeting eIF4A in Leukemia	8
How Useful are Antimicrobial Peptide Properties for Predicting Activity, Selectivity, and Potency?	8
Chloride Intracellular Channel 1 Enhances Glioblastoma Cell Migration and Epithelial-Mesenchymal Transition by Activating the ERK1/2 Signaling Pathway	8
Metallopeptidases as Key Virulence Attributes of Clinically Relevant Protozoa: New Discoveries, Perspectives, and Frontiers of Knowledge	7
Bcl-2 Family Proteins in Therapeutic Arena for Cancers	7
Post Translational Modification and Its Pathologic Association in Rheumatoid Arthritis: A Brief Perspective	7
Recovery of Proteases and Protease Inhibitors from Ganoderma spp. Cultivated in Amazonian Lignocellulose Wastes	7
Kenaf Seed Cysteine Protease (KSCP) Inhibits the Intrinsic Pathway of the Blood Coagulation Cascade and Platelet Aggregation	7
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	6
Manipulating Metabolic Alterations and their Consequences to Unleash the Potential of Antitumor Immunotherapy	6
Trehalose and its Diverse Biological Potential	6
Leishmaniasis: Omics Approaches to Understand its Biology from Molecule to Cell Level	6
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	6
Structure-Function Relationship of Homogentisate 1,2-dioxygenase: Understanding the Genotype-Phenotype Correlations in the Rare Genetic Disease Alkaptonuria	6
Soybean β-Conglycinin: Structure Characteristic, Allergenicity, Plasma Lipid-Controlling, Prevention of Obesity and Non-alcoholic Fatty Liver Disease	6
Identification of Protein Drug Targets of Biofilm Formation and Quorum Sensing in Multidrug Resistant Enterococcus faecalis	6
Peroxiredoxin-6: A Guardian of Lung Pathophysiologies	6
Bacterial Pathogens: Potential Source For Antimicrobial Peptides	6
Birch Pollen Allergens	6
The Fulcrum of Demyelination in Multiple Sclerosis	5
Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	5
Programmed Cell Death in Plants: Insights into Developmental and Stress-Induced Cell Death	5
Biological Significance of EphB4 Expression in Cancer	5
Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases	5
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	5
Understanding the Role of NRF2 Signalling in Cancer	5
Hypoxia A Typical Target in Human Lung Cancer Therapy	5
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	5
Knockdown of Ubiquitin-Conjugating Enzyme E2 T Abolishes the Progression of Head and Neck Squamous Cell Carcinoma by Inhibiting NF-Κb Signaling and inducing Ferroptosis	5
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	5
Decoding the Molecular Mechanisms of miRNAs: Protein Interactions in Schizophrenia Pathogenesis	5
Glucagon-Like Peptide-2 in the Control of Gastrointestinal Motility: Physiological Implications	5
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	5
Lactoferrin as a Potent Natural Supplement Exhibiting a Synergistic Effect with Drugs in Antimicrobial and Anticancer Therapies	5
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres	5
MicroRNA, a Promising Biomarker for Breast and Ovarian Cancer: A Review	4
Novel bone Morphogenetic Protein (BMP)-2/4 Consensus Peptide (BCP) for the Osteogenic Differentiation of C2C12 Cells	4
Withdrawal Notice: Novel Sequence Features of Leucine-rich Repeats in Proteins from Nucleocytoplasmic Large DNA Viruses	4
Short Amphiphiles or Micelle Peptides May Help to Fight Against COVID-19	4
Down-Regulated JDP2 Attenuated Trophoblast Invasion and Migration in Preeclampsia by Inhibiting Epithelial-Mesenchymal Transition through the Wnt/β-Catenin Pathway	4
In-vitro, In-silico Investigations Reveals Potential Cytotoxic Activity of Fermentation Metabolites from Actinomycetes Isolated from Lonar Soda Lake Against HeLa Cancer Cell Lines	4
Plant bZIP Proteins: Potential use in Agriculture - A Review	4
Preface	4
Bioconjugation Techniques for Enhancing Stability and Targeting Efficiency of Protein and Peptide Therapeutics	4

Exploring the Molecular Aspects of Glycosylation in MOG Antibody Disease (MOGAD)	4
Interaction of Nanomaterials with Protein-Peptide	4
PPA1, TRIM68 and FBXO46: Potential Therapeutic Targets for Triple Negative Breast Cancer	4
Influences of Ipomoea batatas Anti-Cancer Peptide on Tomato Defense Genes	4
Preface	4
Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects	4
Molecular Characterization, Expression and In Situ Hybridization Analysis of a Pedal Peptide/Orcokinin-type Neuropeptide in Cuttlefish Sepiella japonica	4
Network Pharmacology and Experiments to Verify the Effect and Potential Mechanism of Baicalein on Osteoporosis	4
Evolution of Immunotherapy Against Pollen Allergy	4
Difference of MreBCD Complex Interactome in Salmonella Typhimurium ST19 and ST213 Genotypes on Pathogenesis and Stress Response Pathways	4
Reconsidering and Reforming the Amyloid Cascade Hypothesis	4
Prognostic Role of Unfolded Protein Response-Related Genes in Hepatocellular Carcinoma	4
Measurement of High Protein Concentrations by Optical Rotation: A Case Study for Monitoring of Monoclonal Antibody Drug Downstream Processes	4
Cell Surface Markers and their Targeted Drugs in Breast Cancer	4