OOIR: Observatory of International Research

Papers

(The TQCC of Current Protein & Peptide Science is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Outdoor Allergens of Regional Importance in Asia	74
The Expression Characteristics and Interrelationships of FNDC5 and Pyroptosis-Associated Molecules in the Peripheral Blood of Patients with Coronary Heart Disease	29
Chaperones as Potential Pharmacological Targets for Treating Protein Aggregation Illness	26
On the Potential Significance of the Intrinsically Disordered Regions in the Clostridiodes difficile Toxins A and B	25
Multiple Facets of Plant-Microbiome Associations in Unlocking the Communication Paradigm through Extracellular Vesicles	25
Withdrawal Notice: Overview of Enzyme Engineering Towards the Production of Hyaluronic Acid with Tailored Molecular Weight	24
Glucagon-Like Peptide-2 in the Control of Gastrointestinal Motility: Physiological Implications	23
Current Drugs and their Therapeutic Targets for Hypoxia-inducible Factors in Cancer	21
Micro RNAs as Emerging Therapeutic Targets in Liver Diseases	21
Specifically targeting Mtb cell-wall and TMM transporter: the development of MmpL3 inhibitors	19
Molecular Players at the Sorting Stations of Malaria Parasite ‘Plasmodium falciparum’	17
Combating Aminoglycoside Resistance: From Structural and Functional Characterisation to Therapeutic Challenges with RKAAT	17
Biology of Bone Morphogenetic Proteins in Skeleton Disease: Osteonecrosis in Sickle Cell Disease Patients	16
Markers of Oxidative Stress and Tyrosinase Activity in Melasma Patients: A Biochemical Investigation	16
Structural Proteomics: Detection of Neurodegenerative Protein Modifications	15
ACKNOWLEDGEMENTS TO REVIEWERS	15
Identification of Protein Drug Targets of Biofilm Formation and Quorum Sensing in Multidrug Resistant Enterococcus faecalis	15
CBX8 Promotes Epithelial-mesenchymal Transition, Migration, and Invasion of Lung Cancer through Wnt/β-catenin Signaling Pathway	14
Review of post-translational modification of human serum albumin	14
Advancements of the CRISPR/Cas9 System in the Treatment of Liver Cancer	14
Exercise and Metabolic Health: The Emerging Roles of Novel Exerkines	13
Revolutionizing Infertility Management through Novel Peptide-based Targets	13
Tribute to Prof. Ben M. Dunn: A Remarkable Biochemist and Editor-in-Chief of Current Protein & Peptide Science and Protein & Peptide Letters	12
Effects of the Amyotrophic Lateral Sclerosis-related Q108P Mutation on the Structural Ensemble Characteristics of CHCHD10	12
The Fulcrum of Demyelination in Multiple Sclerosis	12

Neurokinin B Administration Induces Dose Dependent Proliferation of Seminal Vesicles in Adult Rats	11
Advanced Protein Drugs and Formulations	11
Unveiling the Emerging Role of Klotho: A Comprehensive Narrative Review of an Anti-aging Factor in Human Fertility	11
Current Trends and Challenges in Targeting Tumor Mitochondrial Glycolysis and Oxidative Phosphorylation Pathways for Cancer Therapy	10
Birch Pollen Allergens	10
Serum Irisin is Associated with Bone Mineral Density in Postmenopausal T2dm Patients Complicated with Osteoporosis and in Mice with Diabetic Osteoporosis	10
Hypoxia A Typical Target in Human Lung Cancer Therapy	9
Emerging Role of Non-collagenous Bone Proteins as Osteokines in Extraosseous Tissues	9
Understanding the Role of NRF2 Signalling in Cancer	9
Aspartate β-hydroxylase (ASPH) Accelerates Intrahepatic Cholangiocarcinoma Metastasis via Upregulating SHH Signaling Pathway	8
Thymosin β4 and Actin: Binding Modes, Biological Functions and Clinical Applications	8
Targeting Ovarian Solid Tumors by Elastin-Like Polypeptide Drug Conjugates: Current Trends and Future Prospectives	8
Microbial Enzymes used in Prodrug Activation for Cancer Therapy: Insights and Future Perspectives	8
Targeted Delivery of Diphtheria Toxin into VEGFR1/VEGFR2 Overexpressing Cells Induces Anti-angiogenesis Activity	8
TIPE2 Inhibits Migration and Promotes Apoptosis as a Tumor Suppressor in Hypopharyngeal Carcinoma	7
Natural and Synthetic Peptides to Control Drug-resistant Pathogens	7
Emerging Role of Sorting Nexin 17 in Human Health and Disease	7
Plant Lectins: A Review on their Biotechnological Potential Toward Human Pathogens	7
ARL15 and its Multiple Disease Association: Emerging Functions and Potential Therapeutic Application	7
Tight Junctions in the Auditory System: Structure, Distribution and Function	7
Use of CRISPR in Infection Control	7
MTA1: A Vital Modulator in Prostate Cancer	7
Apolipoprotein-mimetic Peptides: Current and Future Prospectives	6
Research Progress on hCNT3 Structure/Function and Nucleoside Anticancer Drugs	6
Comparison of Laccases and Hemeproteins Systems in Bioremediation of Organic Pollutants	6
Peroxiredoxin-6: A Guardian of Lung Pathophysiologies	6
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy	6
Are Hsp90 Inhibitors Good Candidates Against Covid-19?	6
An Update on Dipeptidyl Peptidase-IV Inhibiting Peptides	5
An Overview of the Deubiquitinase USP53: A Promising Diagnostic Marker and Therapeutic Target	5
Programmed Cell Death in Plants: Insights into Developmental and Stress-Induced Cell Death	5
Neuroinflammation in Alzheimer’s Disease: Focus on NLRP1 and NLRP3 Inflammasomes	5
Current Stage and Future Perspectives for Homology Modeling, Molecular Dynamics Simulations, Machine Learning with Molecular Dynamics, and Quantum Computing for Intrinsically Disordered Proteins and P	5
Mass Spectrometry Techniques: Principles and Practices for Quantitative Proteomics	5
The Roles of IGF-1 and MGF on Nerve Regeneration under Hypoxia- Ischemia, Inflammation, Oxidative Stress, and Physical Trauma	5
A Comprehensive Review on the Significance of Cysteine in Various Metabolic Disorders; Particularly CVD, Diabetes, Renal Dysfunction, and Ischemic Stroke	5
Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma	5
Synaptotagmin-1: A Multi-Functional Protein that Mediates Vesicle Docking, Priming, and Fusion	5
Implications of CRISPR-Cas9 in Developing Next Generation Biofuel: A Mini-review	5
Structure, Distribution, Regulation, and Function of Splice Variant Isoforms of Nitric Oxide Synthase Family in the Nervous System	5
A Mini-Review on the Effectiveness of Peptoids as Therapeutic Interventions against Neurodegenerative Diseases	4
Structure Elucidation and Identification of Novel Lead Molecules against Sulfur Import Protein cysA of Mycobacterium tuberculosis	4
JASMONATE ZIM-DOMAIN Family Proteins: Important Nodes in Jasmonic Acid-Abscisic Acid Crosstalk for Regulating Plant Response to Drought	4
PI3K Signaling Pathways as a Molecular Target for Glioblastoma Multiforme	4
Non-Nitrogen-Containing Bisphosphonates Prevent Pyrophosphorylation of Exocytosis Proteins	4
Antimicrobial Peptides with pH-Dependent Activity and Alkaline Optima: Their Origins, Mechanisms of Action and Potential Applications	4
REST-restrained lncRNA EPB41L4A-AS2 Modulates Laryngeal Squamous Cell Carcinoma Development via Regulating miR-1254/HIPK2 Pathway	4
Histone Methylation Regulation as a Potential Target for Non-alcoholic Fatty Liver Disease	4
Exploring the Potential Role of Phytopharmaceuticals in Alleviating Toxicities of Chemotherapeutic Agents	4
Current Methods for Mass Spectrometric Analysis of Intact Proteins and Peptides	4

Chemometric Study of the Relative Aggregation Propensity of Position 19 Mutants of Aβ(1-42)	4
Acknowledgements to Reviewers	4
Global Emergence of SARS-CoV2 Infection and Scientific Interventions to Contain its Spread	4
Efficient High-throughput Techniques for the Analysis of Disease- Resistant Plant Varieties and Detection of Food Adulteration	4
Recent Progress and Challenges in the Development of Edible Vaccines Produced by Genetically Modified Plants	4
Purification, Characterization and Evaluation of the Anticoagulant Effect of an Uncompetitive Trypsin Inhibitor obtained from Bauhinia pulchella (Benth) Seeds	3
Research Progress on Extracellular Matrix Involved in the Development of Preeclampsia	3
Biological Significance of EphB4 Expression in Cancer	3
An Overview of Databases and Bioinformatics Tools for Plant Antimicrobial Peptides	3
A Comprehensive Comparative Review of Protein Sequence-Based Computational Prediction Models of Lysine Succinylation Sites	3
Reduced Tumor Volume and Increased Necrosis of Human Breast Tumor Xenograft in Mice Pretreated by a Cocktail of Three Specific Anti-HER2 scFvs	3
Phosphate Toxicity and Vascular Calcification in Chronic Kidney Disease: A Closer Look Utilizing Transmission Electron Microscopy	3
A Review of the Common Neurodegenerative Disorders: Current Therapeutic Approaches and the Potential Role of Bioactive Peptides	3
Phase Separation of Chromatin Structure-related Biomolecules: A Driving Force for Epigenetic Regulations	3
Influence of Chaperones on Amyloid Formation of Аβ Peptide	3
Peptide Triazole Inhibitors of HIV-1: Hijackers of Env Metastability	3
ACE2 Receptor: A Potential Pharmacological Target in COVID-19	3
A Review of the Leishmanicidal Properties of Lectins	3
Bioactive Milk Peptides as a Nutraceutical Opportunity and Challenges	3
Comparative Proteomic Analysis of Cell Wall Proteins of Aminoglycosides Resistant and Sensitive Mycobacterium tuberculosis Clinical Isolates	3
Structure and Function of the Important Internalins of Listeria monocytogenes	3
Insights into the Binding of Metadoxine with Bovine Serum Albumin: A Multi-Spectroscopic Investigation Combined with Molecular Docking	3
Current Update on New Delhi Metallo-β-lactamase (NDM) Variants: New Challenges in the Journey of Evolution	3
Mass Spectrometric (MS) Analysis of Proteins and Peptides	3
Identification of Tyrosinase Inhibitory Peptides from Sea Cucumber (Apostichopus japonicus) Collagen by in silico Methods and Study of their Molecular Mechanism	3
Recent Advances in Co-Condensation and Co-Aggregation of Amyloid Proteins Linked to Neurodegenerative Diseases	3
Ubiquitous Existence of Cation-Proton Antiporter and its Structurefunction Interplay: A Clinical Prospect	3
Lactoferrin as a Potent Natural Supplement Exhibiting a Synergistic Effect with Drugs in Antimicrobial and Anticancer Therapies	3
The Disulfide Bond-Mediated Cyclization of Oral Peptides	3
A Study on the Rationality of Baicalein in the Treatment of Osteoporosis: A Narrative Review	3
Overexpression of Efflux Pumps AcrAB and OqxAB Contributes to Ciprofloxacin Resistance in Clinical Isolates of K. pneumoniae	3
Therapeutic Peptides: Unravelling Conformational Dynamics by Systematic Application of Biophysical Techniques	3
Protein Engineering in Cyanobacterial Biotechnology: Tools and Recent Updates	3
Recent Advancement in Novel Wound Healing Therapies by Using Antimicrobial Peptides Derived from Humans and Amphibians	3
Comprehensive Review and Comparison of Anticancer Peptides Identification Models	3
Neurotoxic Aβ: Linking Extracellular and Intracellular Aβ in Alzheimer’s Disease	3
Addition of Mercury Causes Quenching of NIR Fluorescence Emission Spectra of a Photoactivatable PAiRFP1 Protein	3
Progress in the Development of Antimicrobial Peptide Prediction Tools	3