Current Drug Targets

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	40
Meet the Editorial Board Member	38
Cell Entry and Unusual Replication of SARS-CoV-2	37
Meet the Editorial Board Member	33
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	27
Retracted: Meet the Editorial Board Member	27
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	26
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	26
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	25
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	25
The Marburg Virus Outbreak in West Africa	25
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	24
Meet the Regional Editor	24
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	24
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	23
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	22
Xerostomia: Advances and Challenges in Drug Development	22
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	22
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	22
Meet the Editorial Board Member	22
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	20
Meet the Editorial Board Member	19
An Updated Review for the Diabetic Wound Healing Systems	19
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	19
An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	19

Betaine, a Potential Therapeutic Alternative for the Treatment of Depression	19
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	18
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	18
Diabetic Nephropathy: Pathogenesis to Cure	17
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	17
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	17
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	17
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	16
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	16
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	16
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	16
Meet the Editorial Board Member	15
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	15
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	14
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	14
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	14
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	14
Mitochondria-Targeted Nanoformulations: New Therapeutic Strategies and Opportunities for Cancer Immunotherapy	14
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	13
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	12
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	12
Prospection of Microfluidics for Local Drug Delivery	12
Recent Advances in Biomedical Applications of Mannans and Xylans	12
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	12
Potential Targets in Constipation Research: A Review	12
Effect of Rotenone on the Neurodegeneration among Different Models	12
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	11
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	11
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	11
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	11
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	11
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	10
Meet the Editorial Board Member	10
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	10
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	9
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	9
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	9
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9

Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	9
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	9
Nanoformulations - Insights Towards Characterization Techniques	9
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	9
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Meet the Associate Editorial Board Member	8
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	8
A Review of Amylin Peptide Receptor Activators for Obesity Pharmacotherapy	8
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	8
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	8
Acknowledgements to Reviewers	8
Sepsis-Associated Brain Dysfunction: Mechanisms, Clinical Insights, and Therapeutic Strategies	8
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Investigating the Mechanism of Astragalus mongholicus-Mediated Treatment of Silicosis in Mice from the Perspective of Alternative Splicing	8
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	8
Multitarget Compounds for Neglected Diseases: A Review	8
Differential Drug Permeability across Biofilms	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
The Resurgence of H3N2 in India: Is it Life-threatening?	7
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	7
Meet the Editorial Board Member	7
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	6
Meet the Editorial Board Member	6
Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle	6
Polymer-dendrimer Hybrids as Carriers of Anticancer Agents	6
Meet the Regional Editor	6
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders	6
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System	6
Targeted Regulation of Intracellular Signal Transduction: A New Paradigm for Stimulation of Neurogenesis in Alzheimer's Disease	6
Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation of Mucuna pruriens for Parkinson's Disease Treatment	6
Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities	6
Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses	6
The Mechanistic Role of Different Mediators in the Pathophysiology of Nephropathy: A Review	6
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy	6
Bidirectional Relations Between Anxiety, Depression, and Cancer: A Review	6
Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies	6
Cellular Therapeutics for Chronic Wound Healing: Future for Regenerative Medicine	6
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	5
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	5
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	5
Hybrid-Compounds Against Trypanosomiases	5
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	5
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	5
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	5
An Insight into Diverse Activities and Targets of Flavonoids	5
An Update On Proficiency of Voltage-gated Ion Channel Blockers in the Treatment of Inflammation-associated Diseases	5
Directing Hypoxic Tumor Microenvironment and HIF to Illuminate Cancer Immunotherapy's Existing Prospects and Challenges in Drug Targets	5
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	5
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	5
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	5
Strategies and Therapies for Wound Healing: A Review	5
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	5
Meet the Editorial Board Member	5
Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis	5
Role of BMP-7 in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Horizons	5
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	5
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	5
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	5
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	5
Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates	5
NLRP3: A Promising Therapeutic Target for Inflammatory Bowel Disease	5
Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors of Mycobacterium tuberculosis - A Review	5
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	4
Meet the Section Editor	4
Quorum Sensing and its Inhibition in Pseudomonas aeruginosa: Molecular Targets and Mode of Action	4
Deferoxamine Interference in Fibro-inflammation: Additional Action in Control of Obese Adipose Tissue Dysfunction	4
Potential Target of CDK6 Signaling Pathway for Cancer Treatment	4
The Clinical Safety and Efficacy of Targeted PD-L1 Therapy with Durvalumab in Solid Tumors	4
Crucial Role of microRNAs as New Targets for Amelogenesis Disorders Detection	4
Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	4
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	4
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	4
Microbial Synthesis of Gold Nanoparticles and their Application	4
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	4
BRD4 Protein as a Target for Lung Cancer and Hematological Cancer Therapy: A Review	4
Strategies for Treatment of Thyroid Cancer	4
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	4
Innovative Strategies and Advances in Drug Delivery Systems to Address Poor Solubility: A Comprehensive Review	4
Role of Vitamins in Therapeutic and Targeting Approaches for Prostate Cancer: An Overview	4

Current Situation on Diabetes Management: New Weapons Fighting the Disease in 2025	4
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	4
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	4
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	4
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	4
Structural Modifications in Chitosan Polymer Carries Synergistic Transfection in Drug Targeting	4
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	4
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis	4
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases	4
Cytokeratin 8 as a Novel Therapeutic Target in Type 2 Diabetes Mellitus: Suppression of Hepatic Glycogen Synthesis via IRS1/PI3K/Akt/GSK3βSignaling	4
Role of Artificial Intelligence in Nanomedicine and Organ-specific Therapy: An Updated Review	4
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	4
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	4
DRP1 Association in Inflammation and Metastasis: A Review	3
Adipocyte Fatty Acid Binding Protein (A-FABP) as a Potential New Therapeutic Target for the Treatment of Obesity - Associated Cancers	3
Novel Targets and Drug Delivery System in the Treatment of Postoperative Pain: Recent Studies and Clinical Advancement	3
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy	3
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	3
SGK-1 Signalling Pathway is a Key Factor in Cell Survival in Ischemic Injury	3
Targeting SERCA2 in Anti-Tumor Drug Discovery	3
Biomarkers and Treatment Strategies for Breast Cancer Recurrence	3
A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease	3
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	3
Radical Scavenging, Anti-Inflammatory, and Hepatoprotective Activities of Pentacyclic Triterpene isolated from Rosa webbiana	3
Advancing Amyloid Aggregation Research: A Focus on Innovative Therapies, Molecular Modeling and Nano-Delivery Systems in Alzheimer’s Disease	3
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis	3
Adenosine Dysfunction in Epilepsy and Associated Comorbidities	3
The Potential of Mur Enzymes as Targets for Antimicrobial Drug Discovery	3
Therapeutic Potential of Scorpion Venom Proteins: Innovations in Cancer Treatment and Future Directions	3
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	3
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	3
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	3
In Vivo Models of Steroid-Induced Intraocular Hypertension	3
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus	3
An Insight into Hepatitis C Virus: In Search of Promising Drug Targets	3
Omega-3 Fatty Acid Treatment Combined with Chemotherapy to Prevent Toxicity, Drug Resistance, and Metastasis in Cancer	3
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy	3
Redox Interactions in Chemo/Radiation Therapy-induced Lung Toxicity; Mechanisms and Therapy Perspectives	3
Tissue Factor and COVID-19: An Update	3
Tebentafusp as a Promising Drug for the Treatment of Uveal Melanoma	3
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	3
Targeting AMPK Signaling in the Liver: Implications for Obesity and Type 2 Diabetes Mellitus	3
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	3
Compounds Multi-targets against Neglected Diseases	3
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s Disease	3
Combinational Approaches Targeting Various Aspects Involved in Intestinal Barrier Dysfunction-Induced Anxiety	3
The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction	3