Current Drug Targets

Article	Citations
Amendatory Effect of Flavonoids in Alzheimer's Disease Against Mitochondrial Dysfunction	146
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	37
New Advances in Drug Research for Myopia Control in Adolescents	36
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	34
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	30
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	29
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	29
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	27
Cell Entry and Unusual Replication of SARS-CoV-2	25
Meet the Editorial Board Member	25
Retracted: Meet the Editorial Board Member	24
Recent Progress on Apoptotic Activity of Triazoles	24
Meet the Editorial Board Member	23
Tissue Factor and COVID-19: An Update	23
Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease	22
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	20
Nanoformulations - Insights Towards Characterization Techniques	20
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	19
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	19
Quercetin in Oncology: A Phytochemical with Immense Therapeutic Potential	19
Meet the Editorial Board Member	19
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	18
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	18
An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets	18
The Marburg Virus Outbreak in West Africa	18

Thioethers: An Overview	17
Meet the Editorial Board Member	17
Proteasome as a Drug Target in Trypanosomatid Diseases	17
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	16
Therapeutic Potential of HDAC Inhibitors in the Treatment of Cardiac Diseases: A Short Review	16
Nanocarriers for Photodynamic Therapy Intended to Cutaneous Tumors	16
The Fate of Nanoparticles In Vivo and the Strategy of Designing Stealth Nanoparticle for Drug Delivery	16
Strategies and Therapies for Wound Healing: A Review	16
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	15
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	15
The Role of Glycolipids and their Toxicity in the Context of Nanomaterials and Nanoparticles: A Review of the Literature	14
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	14
A Review on Nanotechnologically Derived Phytomedicines for the Treatment of Hepatocellular Carcinoma: Recent Advances in Molecular Mechanism and Drug Targeting	14
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	13
Drug Repurposing Using FDA Adverse Event Reporting System (FAERS) Database	13
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	13
Nrf2 and Ferroptosis: Exploring Translational Avenues for Therapeutic Approaches to Neurological Diseases	13
In Vivo Models of Steroid-Induced Intraocular Hypertension	13
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	13
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	13
Revealing Insights into Natural Products Against mcr-1-Producing Bacteria	13
SGK-1 Signalling Pathway is a Key Factor in Cell Survival in Ischemic Injury	12
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	12
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	12
Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets	12
Canonical Wnt/Beta-Catenin Signaling Network as Emerging Signaling Cascade for Therapeutic Intervention in Chronic Renal Disease	12
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	12
MiRNA, a New Treatment Strategy for Pulmonary Fibrosis	11
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	11
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	11
Role of Poly(ADP-ribose) Polymerase (PARP1) in Viral Infection and its Implication in SARS-CoV-2 Pathogenesis	11
Cytotoxic Flavokawain B Inhibits the Growth and Metastasis of Hepatocellular Carcinoma through UCK2 Modulation of the STAT3/Hif-1α/VEGF Signalling Pathway	11
Targeted Treatment Strategies for Mitochondria Dysfunction: Correlation with Neurological Disorders	11
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	11
N-Heterocycle based Degraders (PROTACs) Manifesting Anticancer Efficacy: Recent Advances	11
Current Research Trends in Cytokine Storm: A Scientometric Study	11
Targeting SERCA2 in Anti-Tumor Drug Discovery	11
Alzheimer's Disease and β-secretase Inhibition: An Update with a Focus on Computer-aided Inhibitor Design	11
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	11
Revolutionizing the World of Pharmaceuticals: Unleashing the Game-Changing Power of 3D Printing	10
Clinical Combinatorial Treatments Based on Cancer Vaccines: Combination with Checkpoint Inhibitors and Beyond	10
GPR56, an Adhesion GPCR with Multiple Roles in Human Diseases, Current Status and Future Perspective	10
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	10
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	10
Exploring AT2R and its Polymorphism in Different Diseases: An Approach to Develop AT2R as a Drug Target beyond Hypertension	10
Microbubbles Contrast Agents: General Overview as Diagnostics and Therapeutic Agent	10
Therapeutic Approaches for Combating Aspergillus Associated Infection	10
Anti-inflammatory Potential of GSK-3 Inhibitors	10
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	9
Hybrid-Compounds Against Trypanosomiases	9

Recent Medicinal Chemistry Studies for Multitarget Agents-Part I	9
Mitochondrial Dysfunction in Huntington’s Disease: Pathogenesis and Therapeutic Opportunities	9
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9
Withdrawal Notice: Obesity: A template to trigger metabolic syndromes and carcinoma. Metformin: A drug target	9
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	9
Meet the Regional Editor	9
The Extracapsular Lymph Node Extension Predicts Outcomes in Colorectal Cancer: A Short Review	9
Corrigendum to: Can Medical Therapy Fix Sexual Dysfunction after Major Pelvic and Prostate Surgery and does it Work for Kidney Stones? Chemotherapy before Cystectomy, New Schemes for which Patients?	8
Meet the Editorial Board Member	8
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	8
Combinatory Approaches Targeting Cognitive Impairments and Memory Enhancement: A Review	8
Biological Potential and Therapeutic Effectiveness of Geiparvarin in Medicine for its Anti-proliferative Activity against Tumors and Other Human Complications	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Pharmacological and Therapeutic Potential of a Natural Flavonoid Icariside II in Human Complication	8
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	8
Meet the Regional Editor	8
Emerging Trends and Future Challenges of Nanovaccine Delivery via Nasal Route	8
Meet the Associate Editorial Board Member	8
Emerging Combinatorial Drug Delivery Strategies for Breast Cancer: A Comprehensive Review	8
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	8
Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis	8
Tebentafusp as a Promising Drug for the Treatment of Uveal Melanoma	7
Meet the Editorial Board Member	7
The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy	7
Meet Our Editorial Board Member	7
Oxidative Stress: Meeting Multiple Targets in Pathogenesis of Vascular Endothelial Dysfunction	7
To Explore the Potential Targets and Current Structure-based Design Strategies Utilizing Co-crystallized Ligand to Combat HCV	7
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	6
Biomimetic Drug Delivery Systems Oriented by Biological Function in Tumor Targeting	6
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	6
Gut Microbiota and Inflammatory Disorders	6
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	6
Meet the Editorial Board Member	6
Therapeutic Correlation of TLR-4 Mediated NF-κB Inflammatory Pathways in Ischemic Injuries	6
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	6
The (Pro)renin Receptor - A Regulatory Nodal Point in Disease Networks	6
Lung Pneumonitis and Fibrosis in Cancer Therapy: A Review on Cellular and Molecular Mechanisms	6
Recent Avenues in Treatment of Liver Diseases: Role of Nanotechnology	6
Meet the Editorial Board Member	6
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	6
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	6
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	5
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	5
Multitarget Compounds for Neglected Diseases: A Review	5
Interplay between DNA Methyltransferase 1 and microRNAs During Tumorigenesis	5
Exploring Spike Protein as Potential Target of Novel Coronavirus and to Inhibit the Viability Utilizing Natural Agents	5
Herbal Resources to Combat a Progressive & Degenerative Nervous System Disorder- Parkinson’s Disease	5
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	5
Application and Future Prospect of Extracellular Matrix Targeted Nanomaterials in Tumor Theranostics	5
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	5
Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics	5
The Surging Mechanistic Role of Angiotensin Converting Enzyme 2 in Human Pathologies: A Potential Approach for Herbal Therapeutics	5
Xerostomia: Advances and Challenges in Drug Development	5
Efficacy and Possible Mechanisms of Astragali Radix and its Ingredients in Animal Models of Osteoporosis: A Preclinical Review and Metaanalysis	5
Targeting AMPK Signaling in the Liver: Implications for Obesity and Type 2 Diabetes Mellitus	4
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	4
Antibiotic Adjuvants: A Promising Approach to Combat Multidrug Resistant Bacteria	4
An Overview of Contemporary and Future Therapeutic Strategies for Scalp Psoriasis	4
Compounds from Natural Products Candidates to Drug for Chikungunya Virus Infection: A Systematic Review	4
The Gut Microbiota and Traditional Chinese Medicine: A New Clinical Frontier on Cancer	4
Assessing Anti-Acne Potentials Via in-vitro, Ex-vivo, and in-vivo Models: A Comprehensive Approach	4
Meet the Associate Editorial Board Member	4
Acknowledgements to Reviewers	4
Retraction Notice to “Meet the Editorial Board Member”	4
Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure	4
Meet the Associate Editorial Board Member	4
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	4
An Updated Review for the Diabetic Wound Healing Systems	4
Post-menopausal Osteoporosis and Probiotics	4
Neurological Complications of SARS-CoV-2 Infection and COVID-19 Vaccines: From Molecular Mechanisms to Clinical Manifestations	4
Exploring Current Role of Nanotechnology Used in Food Processing Industry to Control Food Additives and their Biochemical Mechanisms	4
Colorectal Cancer Epidemiology: Recent Trends and Impact on Outcomes	4
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	4
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	4
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	4
Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons	4
Recent Advancement in Topical Drug Delivery for Psoriasis: Clinical Pertinence and Potential Market	4
TL1A: A New Potential Target in the Treatment of Inflammatory Bowel Disease	4
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	4
Protein-Ligand Interactions: High-Resolution Structures of CDK2	4

A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	4
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	4
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	4
Meet the Editorial Board Member	4
Meet the Regional Editor	4
Meet the Section Editor	4
Breaking Barriers: Current Advances and Future Directions in Mpox Therapy	3
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	3
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	3
Natural Products as Anticancer Agents	3
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	3
Aging of Brain Related with Mitochondrial Dysfunctions	3
GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	3
Targeting Protein Phosphatases for the Treatment of Chronic Liver Disease	3
Therapeutic Potential of Flavonoid Derivatives for Certain Neglected Tropical Diseases	3
GSK-3 Inhibitors: A New Class of Drugs for Alzheimer’s Disease Treatment	3
Potential Role of In Vitro-In Vivo Correlations (IVIVC) for the Development of Plant-Derived Anticancer Drugs	3
Pharmacological Exploration of Triazole-based Therapeutics for Alzheimer’s Disease: An Overview	3
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	3
Therapeutic Potential of Herbal Medicine against Non-alcoholic Fatty Liver Disease	3
Meet the Editorial Board Member	3
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	3
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	3
Meet Our Editorial Board Member	3
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	3
Syndecan-1: A Novel Diagnostic and Therapeutic Target in Liver Diseases	3
Self-Assembled Micelles of Amphiphilic PEGylated Drugs for Cancer Treatment	3
Cytokines and Regulating Epithelial Cell Division	3
Microbial Synthesis of Gold Nanoparticles and their Application	3
Recent Medicinal Chemistry Studies for Multitarget Agents-Part II	3
New Approaches for the Treatment of Chagas Disease	3
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	3
Insight γ-Secretase: Structure, Function, and Role in Alzheimer’s Disease	3
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	3
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	3
Anti-VEGF Mediated Immunomodulatory Role of Phytochemicals: Scientific Exposition for Plausible HCC Treatment	3
Progress in Detection of Insomnia Sleep Disorder: A Comprehensive Review	3
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	2
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	2
Strategies for Controlling Biofilm-forming Microbial Pathogens on Biotic and Abiotic Surfaces	2
Role of Statins in New-onset Diabetes Mellitus: The Underlying Cause, Mechanisms Involved, and Strategies to Combat	2
Current Drug Targets for Gut Microbiota Biocorrection during the SARS-CoV-2 Pandemic: A Systematic Review	2
Targeting mTOR Signaling in Type 2 Diabetes Mellitus and Diabetes Complications	2
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	2
Targeting Triglyceride Metabolism for Colorectal Cancer Prevention and Therapy	2
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	2
Magnetomorph: The Future of Targeted Drug Delivery	2
Differential Drug Permeability across Biofilms	2
Anti-VEGF Therapy in Myopic CNV	2
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	2
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	2
Trends on Nanomedicines as Novel therapeutics Approach in Targeting Nociceptors for Relieving Pain	2
Nanotechnology Based Approach for Hepatocellular Carcinoma Targeting	2
MT1JP: A Pivotal Tumor-Suppressing LncRNA and its Role in Cancer Progression and Therapeutic Potential	2
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	2
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	2
Unraveling Neurological Drug Delivery: Polymeric Nanocarriers for Enhanced Blood-Brain Barrier Penetration	2
Viaminate Inhibits Propionibacterium Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade	2
Intra-articular Treatment with Triamcinolone Hexacetonide Associated with Gold Nanoparticles Reduces Cartilage Degeneration in an Animal Model of Osteoarthritis	2
Emerging Role of NAT10 as ac4C Writer in Inflammatory Diseases: Mechanisms and Therapeutic Applications	2
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	2
Corrigendum to: GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	2
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	2
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	2
Quantum Dot-based Bio-conjugates as an Emerging Bioimaging Tool for Cancer Theranostic- A Review	2
Acknowledgements to Reviewers	2
Acknowledgements to Reviewers	2
An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	2
Diabetic Nephropathy: Pathogenesis to Cure	2
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	2
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	2
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	2
Preclinical Drug Discovery in Colorectal Cancer: A Focus on Natural Compounds	2
Nanotechnology for Targeted Drug Delivery to Treat Osteoporosis	2
In Silico Study Examining New Phenylpropanoids Targets with Antidepressant Activity	2
Flavonoids as G Protein-coupled Receptors Ligands: New Potential Therapeutic Natural Drugs	2
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	2
Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	2
Strategies for Treatment of Thyroid Cancer	2
Recent Advances in the Discovery of GSK-3 Inhibitors from Synthetic Origin in the Treatment of Neurological Disorders	2
Remdesivir and Hydroxychloroquine: A Compassionate Use in Covid-19	2
Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases	2
Gelatin-based Targeted Delivery Systems for Tissue Engineering	2