Current Drug Targets

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	39
Meet the Editorial Board Member	36
Cell Entry and Unusual Replication of SARS-CoV-2	34
Meet the Editorial Board Member	31
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	26
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	26
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	26
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	25
The Marburg Virus Outbreak in West Africa	24
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	23
The Emerging Landscape of LINC01123 in Cancer: Roles, Mechanisms,and Clinical Significance	23
Retracted: Meet the Editorial Board Member	23
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	23
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	22
Betaine, a Potential Therapeutic Alternative for the Treatment of Depression	22
Meet the Regional Editor	22
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	22
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	21
Meet the Editorial Board Member	21
Xerostomia: Advances and Challenges in Drug Development	21
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	20
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	20
An Updated Review for the Diabetic Wound Healing Systems	19
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	19
An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	19

Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	19
Meet the Editorial Board Member	18
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	18
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	17
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	17
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	17
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	17
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	17
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	17
Diabetic Nephropathy: Pathogenesis to Cure	16
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	16
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	16
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	15
Meet the Editorial Board Member	15
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	14
Innovations in Antimalarial Drug Discovery: New Targets and Leads	14
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	14
Acknowledgements to Reviewers	14
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	14
Mitochondria-Targeted Nanoformulations: New Therapeutic Strategies and Opportunities for Cancer Immunotherapy	13
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	13
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	13
Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy	13
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	13
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	13
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Tachykinin Receptors and Their Antagonists: Unraveling Their Role inMetabolic Disorders and Therapeutic Innovations	12
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	12
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	12
ACE2 as a Key Target for Treatment of COVID-19 Related Cardiovascular Diseases: Current Progress and Prospect	12
Prospection of Microfluidics for Local Drug Delivery	12
Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma	12
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	11
Effect of Rotenone on the Neurodegeneration among Different Models	11
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	11
Potential Targets in Constipation Research: A Review	11
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	11
Recent Advances in Biomedical Applications of Mannans and Xylans	11
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	10
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway	10
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	10

Meet the Editorial Board Member	10
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	9
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	9
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	9
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	9
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	9
Nanoformulations - Insights Towards Characterization Techniques	9
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	9
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	8
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	8
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	8
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
A Review of Amylin Peptide Receptor Activators for Obesity Pharmacotherapy	8
Multitarget Compounds for Neglected Diseases: A Review	8
Investigating the Mechanism of Astragalus mongholicus-Mediated Treatment of Silicosis in Mice from the Perspective of Alternative Splicing	8
Sepsis-Associated Brain Dysfunction: Mechanisms, Clinical Insights, and Therapeutic Strategies	8
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	7
Acknowledgements to Reviewers	7
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
Meet the Associate Editorial Board Member	7
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	7
Differential Drug Permeability across Biofilms	7
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System	6
Meet the Editorial Board Member	6
Meet the Editorial Board Member	6
Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses	6
Cellular Therapeutics for Chronic Wound Healing: Future for Regenerative Medicine	6
The Resurgence of H3N2 in India: Is it Life-threatening?	6
The Mechanistic Role of Different Mediators in the Pathophysiology of Nephropathy: A Review	6
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders	6
Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies	6
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	6
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy	6
Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities	6
Polymer-dendrimer Hybrids as Carriers of Anticancer Agents	6
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	5
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	5
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	5
An Update On Proficiency of Voltage-gated Ion Channel Blockers in the Treatment of Inflammation-associated Diseases	5
Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis	5
Targeted Regulation of Intracellular Signal Transduction: A New Paradigm for Stimulation of Neurogenesis in Alzheimer's Disease	5
Meet the Editorial Board Member	5
Meet the Editorial Board Member	5
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	5
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	5
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	5
NLRP3: A Promising Therapeutic Target for Inflammatory Bowel Disease	5
Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle	5
Bidirectional Relations Between Anxiety, Depression, and Cancer: A Review	5
Small-molecule Antiviral Agents in Ongoing Clinical Trials for COVID-19	5
An Insight into Diverse Activities and Targets of Flavonoids	5
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	5
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	5
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	5
Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors of Mycobacterium tuberculosis - A Review	5
Meet the Regional Editor	5
Directing Hypoxic Tumor Microenvironment and HIF to Illuminate Cancer Immunotherapy's Existing Prospects and Challenges in Drug Targets	5
Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates	5
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	4
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	4
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	4
Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	4
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	4
GSK-3 Inhibitors: A New Class of Drugs for Alzheimer’s Disease Treatment	4
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	4
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	4
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	4
Role of BMP-7 in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Horizons	4
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	4
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	4
Adipocyte Fatty Acid Binding Protein (A-FABP) as a Potential New Therapeutic Target for the Treatment of Obesity - Associated Cancers	4
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	4

Quorum Sensing and its Inhibition in Pseudomonas aeruginosa: Molecular Targets and Mode of Action	4
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	4
Meet the Section Editor	4
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	4
Hybrid-Compounds Against Trypanosomiases	4
Strategies and Therapies for Wound Healing: A Review	4
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	4
Deferoxamine Interference in Fibro-inflammation: Additional Action in Control of Obese Adipose Tissue Dysfunction	4
BRD4 Protein as a Target for Lung Cancer and Hematological Cancer Therapy: A Review	4
Structural Modifications in Chitosan Polymer Carries Synergistic Transfection in Drug Targeting	4
Microbial Synthesis of Gold Nanoparticles and their Application	4
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	4
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	4
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	4
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	4
Innovative Strategies and Advances in Drug Delivery Systems to AddressPoor Solubility: A Comprehensive Review	3
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy	3
Current Situation on Diabetes Management: New Weapons Fighting the Disease in 2025	3
Novel Targets and Drug Delivery System in the Treatment of Postoperative Pain: Recent Studies and Clinical Advancement	3
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus	3
The Potential of Mur Enzymes as Targets for Antimicrobial Drug Discovery	3
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s Disease	3
The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction	3
Compounds Multi-targets against Neglected Diseases	3
The Clinical Safety and Efficacy of Targeted PD-L1 Therapy with Durvalumab in Solid Tumors	3
Strategies for Treatment of Thyroid Cancer	3
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases	3
Role of Artificial Intelligence in Nanomedicine and Organ-specific Therapy: An Updated Review	3
Role of Vitamins in Therapeutic and Targeting Approaches for Prostate Cancer: An Overview	3
Advancing Amyloid Aggregation Research: A Focus on Innovative Therapies, Molecular Modeling and Nano-Delivery Systems in Alzheimer’s Disease	3
In Vivo Models of Steroid-Induced Intraocular Hypertension	3
Omega-3 Fatty Acid Treatment Combined with Chemotherapy to Prevent Toxicity, Drug Resistance, and Metastasis in Cancer	3
Inflammatory Bowel Disease in Migrant Populations: Should we Look Even Further Back?	3
A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease	3
DRP1 Association in Inflammation and Metastasis: A Review	3
Potential Target of CDK6 Signaling Pathway for Cancer Treatment	3
Redox Interactions in Chemo/Radiation Therapy-induced Lung Toxicity; Mechanisms and Therapy Perspectives	3
Adenosine Dysfunction in Epilepsy and Associated Comorbidities	3
Cytokeratin 8 as a Novel Therapeutic Target in Type 2 Diabetes Mellitus: Suppression of Hepatic Glycogen Synthesis via IRS1/PI3K/Akt/GSK3βSignaling	3
Crucial Role of microRNAs as New Targets for Amelogenesis Disorders Detection	3
Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace	3
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy	3
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis	3
Combinational Approaches Targeting Various Aspects Involved in Intestinal Barrier Dysfunction-Induced Anxiety	3
Radical Scavenging, Anti-Inflammatory, and Hepatoprotective Activities of Pentacyclic Triterpene isolated from Rosa webbiana	3
Biomarkers and Treatment Strategies for Breast Cancer Recurrence	3
An Insight into Hepatitis C Virus: In Search of Promising Drug Targets	3
Meet the Editorial Board Member	3
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	3
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis	3