Current Drug Targets

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	37
Meet the Editorial Board Member	36
Cell Entry and Unusual Replication of SARS-CoV-2	34
Meet the Editorial Board Member	30
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	29
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	26
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	24
Retracted: Meet the Editorial Board Member	24
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	23
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	23
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	22
The Marburg Virus Outbreak in West Africa	22
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	21
Meet the Editorial Board Member	21
Meet the Regional Editor	21
Xerostomia: Advances and Challenges in Drug Development	20
An Updated Review for the Diabetic Wound Healing Systems	20
Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons	20
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	20
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	19
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	19
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	19
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	19
Meet the Editorial Board Member	18
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	18

An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	18
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	17
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	17
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	17
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	17
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	17
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	17
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	15
Acknowledgements to Reviewers	15
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	15
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	15
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	15
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	15
Meet the Editorial Board Member	15
Diabetic Nephropathy: Pathogenesis to Cure	15
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	14
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	14
Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy	14
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	14
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	14
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	12
ACE2 as a Key Target for Treatment of COVID-19 Related Cardiovascular Diseases: Current Progress and Prospect	12
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	12
Prospection of Microfluidics for Local Drug Delivery	12
Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma	12
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Potential Targets in Constipation Research: A Review	12
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	12
Impaired Quality Control of Mitochondria Underlying the Pathogenesis of Alzheimer's Disease	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	11
Effect of Rotenone on the Neurodegeneration among Different Models	11
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	11
Recent Advances in Biomedical Applications of Mannans and Xylans	11
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	11
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	10
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	10
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	10
Meet the Editorial Board Member	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	10
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	10

Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	10
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	10
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	9
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	9
Nanoformulations - Insights Towards Characterization Techniques	9
Anti-inflammatory Potential of GSK-3 Inhibitors	9
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	8
Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure	8
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	8
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	8
Multitarget Compounds for Neglected Diseases: A Review	8
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	7
Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Differential Drug Permeability across Biofilms	7
Meet the Associate Editorial Board Member	7
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	7
Acknowledgements to Reviewers	7
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	7
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
The Resurgence of H3N2 in India: Is it Life-threatening?	6
Meet the Editorial Board Member	6
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System	6
Cellular Therapeutics for Chronic Wound Healing: Future for Regenerative Medicine	6
The Mechanistic Role of Different Mediators in the Pathophysiology of Nephropathy: A Review	6
Meet the Editorial Board Member	6
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	6
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	6
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy	6
An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases	5
Meet the Regional Editor	5
Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses	5
Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies	5
Directing Hypoxic Tumor Microenvironment and HIF to Illuminate Cancer Immunotherapy's Existing Prospects and Challenges in Drug Targets	5
Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates	5
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	5
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	5
Meet the Editorial Board Member	5
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	5
Small-molecule Antiviral Agents in Ongoing Clinical Trials for COVID-19	5
Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities	5
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders	5
An Update On Proficiency of Voltage-gated Ion Channel Blockers in the Treatment of Inflammation-associated Diseases	5
Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle	5
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	5
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	5
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	5
Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors of Mycobacterium tuberculosis - A Review	5
Meet the Editorial Board Member	5
Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis	5
Targeted Regulation of Intracellular Signal Transduction: A New Paradigm for Stimulation of Neurogenesis in Alzheimer's Disease	5
Polymer-dendrimer Hybrids as Carriers of Anticancer Agents	5
Bidirectional Relations Between Anxiety, Depression, and Cancer: A Review	5
An Insight into Diverse Activities and Targets of Flavonoids	5
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	5
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	5
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	5
NLRP3: A Promising Therapeutic Target for Inflammatory Bowel Disease	5
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	4
Hybrid-Compounds Against Trypanosomiases	4
Recent Advancement in Topical Drug Delivery for Psoriasis: Clinical Pertinence and Potential Market	4
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	4
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	4
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	4
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	4
Microbial Synthesis of Gold Nanoparticles and their Application	4
GSK-3 Inhibitors: A New Class of Drugs for Alzheimer’s Disease Treatment	4
Meet the Section Editor	4
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	4
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	4
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	4
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	4
Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases	4

Quorum Sensing and its Inhibition in Pseudomonas aeruginosa: Molecular Targets and Mode of Action	4
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	4
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	4
Meet the Editorial Board Member	4
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	4
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	4
Strategies and Therapies for Wound Healing: A Review	4
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	4
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	4
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	4
GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	4
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	4
Crucial Role of microRNAs as New Targets for Amelogenesis Disorders Detection	3
Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace	3
Adipocyte Fatty Acid Binding Protein (A-FABP) as a Potential New Therapeutic Target for the Treatment of Obesity - Associated Cancers	3
Novel Targets and Drug Delivery System in the Treatment of Postoperative Pain: Recent Studies and Clinical Advancement	3
BRD4 Protein as a Target for Lung Cancer and Hematological Cancer Therapy: A Review	3
Adenosine Dysfunction in Epilepsy and Associated Comorbidities	3
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases	3
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy	3
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s Disease	3
Role of Artificial Intelligence in Nanomedicine and Organ-specific Therapy: An Updated Review	3
Combinational Approaches Targeting Various Aspects Involved in Intestinal Barrier Dysfunction-Induced Anxiety	3
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	3
Compounds Multi-targets against Neglected Diseases	3
Deferoxamine Interference in Fibro-inflammation: Additional Action in Control of Obese Adipose Tissue Dysfunction	3
Review of the Biological Activity of Maslinic Acid	3
The Clinical Safety and Efficacy of Targeted PD-L1 Therapy with Durvalumab in Solid Tumors	3
Structural Modifications in Chitosan Polymer Carries Synergistic Transfection in Drug Targeting	3
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy	3
Advancing Amyloid Aggregation Research: A Focus on Innovative Therapies, Molecular Modeling and Nano-Delivery Systems in Alzheimer’s Disease	3
Inflammatory Bowel Disease in Migrant Populations: Should we Look Even Further Back?	3
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus	3
Redox Interactions in Chemo/Radiation Therapy-induced Lung Toxicity; Mechanisms and Therapy Perspectives	3
Omega-3 Fatty Acid Treatment Combined with Chemotherapy to Prevent Toxicity, Drug Resistance, and Metastasis in Cancer	3
Potential Target of CDK6 Signaling Pathway for Cancer Treatment	3
DRP1 Association in Inflammation and Metastasis: A Review	3
Role of Vitamins in Therapeutic and Targeting Approaches for Prostate Cancer: An Overview	3
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis	3
Strategies for Treatment of Thyroid Cancer	3
Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	3
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis	3
Meet the Editorial Board Member	3
An Insight into Hepatitis C Virus: In Search of Promising Drug Targets	3
Radical Scavenging, Anti-Inflammatory, and Hepatoprotective Activities of Pentacyclic Triterpene isolated from Rosa webbiana	3
Innovative Strategies and Advances in Drug Delivery Systems to Address Poor Solubility: A Comprehensive Review	3
The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction	3
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	2
Development of Novel Intravesical Formulation for Bladder Retention Targeting Bladder Disorders	2
Biomarkers and Treatment Strategies for Breast Cancer Recurrence	2
GSTP1, PRDX2 and NFE2L2: Potential Markers for Primary Stage Breast Cancer	2
Multitargeting: An Alternative Approach to Tackle Multidrug Resistance in Tuberculosis	2
Bacterial Metalo-Aminopeptidases as Targets in Human Infectious Diseases	2
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	2
Remdesivir and Hydroxychloroquine: A Compassionate Use in Covid-19	2
The Extracapsular Lymph Node Extension Predicts Outcomes in Colorectal Cancer: A Short Review	2
Targeting Protein Phosphatases for the Treatment of Chronic Liver Disease	2
Canonical Wnt/Beta-Catenin Signaling Network as Emerging Signaling Cascade for Therapeutic Intervention in Chronic Renal Disease	2
Viaminate Inhibits Propionibacterium Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade	2
Role of Poly(ADP-ribose) Polymerase (PARP1) in Viral Infection and its Implication in SARS-CoV-2 Pathogenesis	2
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	2
The Potential of Mur Enzymes as Targets for Antimicrobial Drug Discovery	2
Recent Progress on Apoptotic Activity of Triazoles	2
Acknowledgements to Reviewers	2
Emerging Therapeutic Targets in Rheumatoid Arthritis: Focusing on HIF-1α, Nrf2, STATs, and RORγt	2
Protective Roles and Mechanism of Action of Plant Flavonoids against Hepatic Impairment: Recent Developments	2
Corrigendum to: GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	2
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	2
Meet the Editorial Board Member	2
SGK-1 Signalling Pathway is a Key Factor in Cell Survival in Ischemic Injury	2
Therapeutic Potential of Flavonoid Derivatives for Certain Neglected Tropical Diseases	2
Emerging Role of NAT10 as ac4C Writer in Inflammatory Diseases: Mechanisms and Therapeutic Applications	2
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	2
In Vivo Models of Steroid-Induced Intraocular Hypertension	2
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	2
A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease	2
Targeting AMPK Signaling in the Liver: Implications for Obesity and Type 2 Diabetes Mellitus	2
Tebentafusp as a Promising Drug for the Treatment of Uveal Melanoma	2
Quantum Dot-based Bio-conjugates as an Emerging Bioimaging Tool for Cancer Theranostic- A Review	2
Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis	2
A Scoping New Revolution for Tinnitus Management: A Neuromonics Narrative Review	2
Targeting SERCA2 in Anti-Tumor Drug Discovery	2
Trends on Nanomedicines as Novel therapeutics Approach in Targeting Nociceptors for Relieving Pain	2
Mitochondrial Dysfunction in Huntington’s Disease: Pathogenesis and Therapeutic Opportunities	2
Intra-articular Treatment with Triamcinolone Hexacetonide Associated with Gold Nanoparticles Reduces Cartilage Degeneration in an Animal Model of Osteoarthritis	2
MT1JP: A Pivotal Tumor-Suppressing LncRNA and its Role in Cancer Progression and Therapeutic Potential	2
Tissue Factor and COVID-19: An Update	2
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	2