Current Drug Targets

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	45
Meet the Editorial Board Member	37
Cell Entry and Unusual Replication of SARS-CoV-2	35
Meet the Editorial Board Member	34
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	33
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	30
Retracted: Meet the Editorial Board Member	27
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	26
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	24
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	24
The Marburg Virus Outbreak in West Africa	23
Antibiotic Adjuvants: A Promising Approach to Combat Multidrug Resistant Bacteria	22
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	22
Meet the Regional Editor	22
Meet the Editorial Board Member	21
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	21
Xerostomia: Advances and Challenges in Drug Development	20
Current Perspectives of Healthy Mitochondrial Function for Healthy Neurons	20
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	20
An Updated Review for the Diabetic Wound Healing Systems	19
Gamma Secretase Inhibitor: Therapeutic Target via NOTCH Signaling in T Cell Acute Lymphoblastic Leukemia	19
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	19
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	19
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	19
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	19

An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	18
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	18
Meet the Editorial Board Member	18
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	18
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	18
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	17
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	17
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	17
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	16
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	16
Diabetic Nephropathy: Pathogenesis to Cure	16
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	15
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	15
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	15
Acknowledgements to Reviewers	15
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	15
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	15
Meet the Editorial Board Member	15
Implications of microRNAs in the Pathogenesis of Atherosclerosis and Prospects for Therapy	14
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	14
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	14
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	14
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	14
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	14
ACE2 as a Key Target for Treatment of COVID-19 Related Cardiovascular Diseases: Current Progress and Prospect	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
Dysregulation of Lysyl Oxidases Expression in Diabetic Nephropathy and Renal Cell Carcinoma	13
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	13
Effect of Rotenone on the Neurodegeneration among Different Models	13
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	13
Prospection of Microfluidics for Local Drug Delivery	12
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	12
Impaired Quality Control of Mitochondria Underlying the Pathogenesis of Alzheimer's Disease	12
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	12
Recent Advances in Biomedical Applications of Mannans and Xylans	12
Potential Targets in Constipation Research: A Review	12
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	12
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	12
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	11
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	11
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	11
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	11
Role of γ-Secretase Inhibitors for the Treatment of Diverse Disease Conditions through Inhibition of Notch Signaling Pathway	11
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	11
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	10
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	10
Proteasome as a Drug Target in Trypanosomatid Diseases	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	10
Anti-inflammatory Potential of GSK-3 Inhibitors	10

Meet the Editorial Board Member	10
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	10
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	10
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	10
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	10
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	10
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	10
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	10
Nanoformulations - Insights Towards Characterization Techniques	10
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	9
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	9
Cerebrovascular Complications of Diabetes: SGLT-2 Inhibitors as a Promising Future Therapeutics	9
Multitarget Compounds for Neglected Diseases: A Review	9
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	9
Anti-VEGF Mediated Immunomodulatory Role of Phytochemicals: Scientific Exposition for Plausible HCC Treatment	8
3D Printing Technology in Pharmaceutical Dosage Forms: Advantages and Challenges	8
Meet the Associate Editorial Board Member	8
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	8
Role of GSK-3 in Cardiac Health: Focusing on Cardiac Remodeling and Heart Failure	8
Acknowledgements to Reviewers	8
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	8
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	8
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	7
The Mechanistic Role of Different Mediators in the Pathophysiology of Nephropathy: A Review	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Recent Advances in the Discovery of GSK-3 Inhibitors from Synthetic Origin in the Treatment of Neurological Disorders	7
Anti-Degenerative Effect of Melatonin on Intervertebral Disc: Protective Contribution against Inflammation, Oxidative Stress, Apoptosis, and Autophagy	7
Meet the Editorial Board Member	7
An Update on the Emerging Role of Wnt/β-catenin, SYK, PI3K/AKT, and GM-CSF Signaling Pathways in Rheumatoid Arthritis	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
A Review on Development and Characterization of a Cost-effective Targeted Quality-driven Antimalarial Product with an Emphasis on Phytosomes	7
Differential Drug Permeability across Biofilms	7
Surface Functionalized Lipid Nanoparticles in Promoting Therapeutic Outcomes: An Insight View of the Dynamic Drug Delivery System	7
The Resurgence of H3N2 in India: Is it Life-threatening?	7
Roadmap to Pyruvate Kinase M2 Modulation - A Computational Chronicle	6
Targeted Regulation of Intracellular Signal Transduction: A New Paradigm for Stimulation of Neurogenesis in Alzheimer's Disease	6
Bidirectional Relations Between Anxiety, Depression, and Cancer: A Review	6
Meet the Editorial Board Member	6
Endemic and Indigenous Plants from Mascarene Islands with Antiviral Propensities	6
Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses	6
Polymer-dendrimer Hybrids as Carriers of Anticancer Agents	6
Cellular Therapeutics for Chronic Wound Healing: Future for Regenerative Medicine	6
Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies	6
A Comprehensive Review on Therapeutic Potential of a Natural Anthraquinone Derivative Emodin in Brain-related Disorders	6
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	5
An Insight into Diverse Activities and Targets of Flavonoids	5
Polypharmacology-Driven Discovery and Design of Highly Selective, Dual and Multitargeting Inhibitors of Mycobacterium tuberculosis - A Review	5
Natural Bioactive Compounds as Emerging Therapeutic Molecules Against Breast Cancer: Emphasis on the Role of Phytoestrogens	5
Parkinson’s Disease: A Current Perspectives on Parkinson’s Disease and Key Bioactive Natural Compounds as Future Potential Drug Candidates	5
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	5
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	5
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	5
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	5
An Insight Into Mitochondrial Dysfunction and its Implications in Neurological Diseases	5
Meet the Editorial Board Member	5
Two Decades Rituximab Therapy in Anti-Neutrophil Cytoplasmic Antibody Associated Vasculitis	5
An Update On Proficiency of Voltage-gated Ion Channel Blockers in the Treatment of Inflammation-associated Diseases	5
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	5
Nanocarriers for Photodynamic Therapy Intended to Cutaneous Tumors	5
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	5
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	5
Directing Hypoxic Tumor Microenvironment and HIF to Illuminate Cancer Immunotherapy's Existing Prospects and Challenges in Drug Targets	5
NLRP3: A Promising Therapeutic Target for Inflammatory Bowel Disease	5
Small-molecule Antiviral Agents in Ongoing Clinical Trials for COVID-19	5
Meet the Regional Editor	5
Meet the Editorial Board Member	5
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	5
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	5
Strategies and Therapies for Wound Healing: A Review	5
Advances in Protein-Ligand Binding Affinity Prediction via Deep Learning: A Comprehensive Study of Datasets, Data Preprocessing Techniques, and Model Architectures	4
Microbial Synthesis of Gold Nanoparticles and their Application	4
Nano Architect-Based Targeted Delivery Systems for Diabetic Nephropathy: A Review	4
Meet the Section Editor	4
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	4
Mesenchymal Stem Cells and Cancer Stem Cells: An Overview of Tumor- Mesenchymal Stem Cell Interaction for Therapeutic Interventions	4
Hybrid-Compounds Against Trypanosomiases	4
Role of Mitochondrial Heat-shock Proteins and Immunophilins in Neuro Degenerative Diseases	4

Antiobesity Drug Discovery Research: In vitro Models for Shortening the Drug Discovery Pipeline	4
GSK-3 Inhibitors: A New Class of Drugs for Alzheimer’s Disease Treatment	4
Promising New Targets for the Treatment of Infections Caused by Acinetobacter baumannii: A Review	4
GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	4
Therapeutic Potential of Targeting Transforming Growth Factor-beta (TGF-β) and Programmed Death-ligand 1 (PD-L1) in Pancreatic Cancer	4
Meet the Editorial Board Member	4
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	4
A Review on CRISPR-mediated Epigenome Editing: A Future Directive for Therapeutic Management of Cancer	4
Recent Progress and Challenges in Clinical Translation of Nanomedicines in Diagnosis and Treatment of Lung Cancer	4
Comprehensive Analysis of Omicron Subvariants: EG.5 Rise, Vaccination Strategies, and Global Impact	4
Promising Protective Effects of Chrysin in Cardiometabolic Diseases	4
Quorum Sensing and its Inhibition in Pseudomonas aeruginosa: Molecular Targets and Mode of Action	4
A Comprehensive Review on Liver Targeting: Emphasis on Nanotechnology- based Molecular Targets and Receptors Mediated Approaches	4
Digoxin and Outcomes in Patients with Heart Failure and Preserved Ejection Fraction (HFpEF) Patients: A Systematic Review and Meta- Analysis	4
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	4
Recent Advancement in Topical Drug Delivery for Psoriasis: Clinical Pertinence and Potential Market	4
A Comprehensive Review on Nanomedicine: Promising Approach for Treatment of Brain Tumor through Intranasal Administration	4
Antiviral Potential of Traditional Unani Medicine with Special Emphasis on Dengue: A Review	4
Structural Modifications in Chitosan Polymer Carries Synergistic Transfection in Drug Targeting	4
Novel Targets and Drug Delivery System in the Treatment of Postoperative Pain: Recent Studies and Clinical Advancement	3
Omega-3 Fatty Acid Treatment Combined with Chemotherapy to Prevent Toxicity, Drug Resistance, and Metastasis in Cancer	3
A Revisit to Etiopathogenesis and Therapeutic Strategies in Alzheimer’s Disease	3
A Review on Recent Development of Novel Heterocycles as Acetylcholinesterase Inhibitor for the Treatment of Alzheimer’s Disease	3
Potential Target of CDK6 Signaling Pathway for Cancer Treatment	3
The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction	3
Review of the Biological Activity of Maslinic Acid	3
Adenosine Dysfunction in Epilepsy and Associated Comorbidities	3
Toxic, Genotoxic and Teratogenic Effects of Ibuprofen and its Derivatives	3
Strategies for Treatment of Thyroid Cancer	3
Extracellular Vesicles from Stromal Vascular Fraction of Human Adipose Tissue in the Development of Non-antibiotic Therapy	3
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis	3
The Clinical Safety and Efficacy of Targeted PD-L1 Therapy with Durvalumab in Solid Tumors	3
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	3
Inflammatory Bowel Disease in Migrant Populations: Should we Look Even Further Back?	3
The Potential of Mur Enzymes as Targets for Antimicrobial Drug Discovery	3
Radical Scavenging, Anti-Inflammatory, and Hepatoprotective Activities of Pentacyclic Triterpene isolated from Rosa webbiana	3
Innovative Strategies and Advances in Drug Delivery Systems to Address Poor Solubility: A Comprehensive Review	3
Compounds Multi-targets against Neglected Diseases	3
Crucial Role of microRNAs as New Targets for Amelogenesis Disorders Detection	3
Deferoxamine Interference in Fibro-inflammation: Additional Action in Control of Obese Adipose Tissue Dysfunction	3
Role of Vitamins in Therapeutic and Targeting Approaches for Prostate Cancer: An Overview	3
Adipocyte Fatty Acid Binding Protein (A-FABP) as a Potential New Therapeutic Target for the Treatment of Obesity - Associated Cancers	3
Redox Interactions in Chemo/Radiation Therapy-induced Lung Toxicity; Mechanisms and Therapy Perspectives	3
Advancing Amyloid Aggregation Research: A Focus on Innovative Therapies, Molecular Modeling and Nano-Delivery Systems in Alzheimer’s Disease	3
Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy	3
An Insight into Hepatitis C Virus: In Search of Promising Drug Targets	3
Biomarkers and Treatment Strategies for Breast Cancer Recurrence	3
Combinational Approaches Targeting Various Aspects Involved in Intestinal Barrier Dysfunction-Induced Anxiety	3
Investigational Agents Targeting SGLT1 and SGLT2 in the Treatment of Type 2 Diabetes Mellitus	3
Role of Artificial Intelligence in Nanomedicine and Organ-specific Therapy: An Updated Review	3
Antiplatelet Effects of Bioactive Compounds Present in Tomato Pomace	3
Meet the Editorial Board Member	3
Molecular Complex of HSIM-loaded Polymeric Nanoparticles: Potential Carriers in Osteoporosis	3
Deciphering the Role of Pyroptosis Impact on Cardiovascular Diseases	3
BRD4 Protein as a Target for Lung Cancer and Hematological Cancer Therapy: A Review	3
DRP1 Association in Inflammation and Metastasis: A Review	3
Protective Roles and Mechanism of Action of Plant Flavonoids against Hepatic Impairment: Recent Developments	2
Corrigendum to: GSK-3 Inhibitors in the Regulation and Control of Colon Carcinoma	2
Mitochondrial Dysfunction in Huntington’s Disease: Pathogenesis and Therapeutic Opportunities	2
ATP Synthase, an Emerging Target in TB Drug Discovery: Review of SAR and Clinical Pharmacology of Diarylquinoline Inhibitors	2
Intra-articular Treatment with Triamcinolone Hexacetonide Associated with Gold Nanoparticles Reduces Cartilage Degeneration in an Animal Model of Osteoarthritis	2
MT1JP: A Pivotal Tumor-Suppressing LncRNA and its Role in Cancer Progression and Therapeutic Potential	2
Canonical Wnt/Beta-Catenin Signaling Network as Emerging Signaling Cascade for Therapeutic Intervention in Chronic Renal Disease	2
In Vivo Models of Steroid-Induced Intraocular Hypertension	2
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	2
Role of Poly(ADP-ribose) Polymerase (PARP1) in Viral Infection and its Implication in SARS-CoV-2 Pathogenesis	2
Meet the Editorial Board Member	2
GSTP1, PRDX2 and NFE2L2: Potential Markers for Primary Stage Breast Cancer	2
Multitargeting: An Alternative Approach to Tackle Multidrug Resistance in Tuberculosis	2
Chitosan-Based Nanocarriers for Pulmonary and Intranasal Drug Delivery Systems: A Comprehensive Overview of their Applications	2
Meet the Editorial Board Member	2
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	2
Emerging Role of NAT10 as ac4C Writer in Inflammatory Diseases: Mechanisms and Therapeutic Applications	2
Insight γ-Secretase: Structure, Function, and Role in Alzheimer’s Disease	2
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	2
Tissue Factor and COVID-19: An Update	2
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	2
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	2
Therapeutic Potential of Flavonoid Derivatives for Certain Neglected Tropical Diseases	2
Glycogen Synthase Kinase-3 (GSK-3) Inhibitors as a New Lead for Treating Breast and Ovarian Cancer	2
Emerging Therapeutic Targets in Rheumatoid Arthritis: Focusing on HIF-1α, Nrf2, STATs, and RORγt	2
Lipidomics in Breast Cancer: Decoding Metabolic Reprogramming and Unlocking Therapeutic Opportunities	2
Bacterial Metalo-Aminopeptidases as Targets in Human Infectious Diseases	2
Meet the Regional Editor	2
Remdesivir and Hydroxychloroquine: A Compassionate Use in Covid-19	2
Targeting SERCA2 in Anti-Tumor Drug Discovery	2
Viaminate Inhibits Propionibacterium Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade	2
Oncostatin M: Risks and Benefits of a Novel Therapeutic Target for Atherosclerosis	2
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	2
Recent Progress on Apoptotic Activity of Triazoles	2
Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease	2
Trends on Nanomedicines as Novel therapeutics Approach in Targeting Nociceptors for Relieving Pain	2
Targeting Protein Phosphatases for the Treatment of Chronic Liver Disease	2
A Scoping New Revolution for Tinnitus Management: A Neuromonics Narrative Review	2
Quantum Dot-based Bio-conjugates as an Emerging Bioimaging Tool for Cancer Theranostic- A Review	2