OOIR: Observatory of International Research

Papers

(The TQCC of Current Drug Targets is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Amendatory Effect of Flavonoids in Alzheimer's Disease Against Mitochondrial Dysfunction	146
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	37
New Advances in Drug Research for Myopia Control in Adolescents	36
The Marriage between Nanotechnology and Stem Cells Secretome for COPD	34
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	30
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	29
The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases	29
Nanocarriers’- An efficient drug delivery system for neurodegenerative disorders including Alzheimer’s, Parkinson’s, Huntington, Amyotrophic lateral sclerosis and associated risk of nanocarriers, futu	27
Cell Entry and Unusual Replication of SARS-CoV-2	25
Meet the Editorial Board Member	25
Retracted: Meet the Editorial Board Member	24
Recent Progress on Apoptotic Activity of Triazoles	24
Meet the Editorial Board Member	23
Tissue Factor and COVID-19: An Update	23
Recent Advances in Nanotechnology-Based Drug Delivery Approaches for Alzheimer disease	22
Recent Advances in the Prevention and Management of Monkeypox Viral Infection in Humans	20
Nanoformulations - Insights Towards Characterization Techniques	20
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	19
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	19
Quercetin in Oncology: A Phytochemical with Immense Therapeutic Potential	19
Meet the Editorial Board Member	19
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	18
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	18
An Agathokakological Tale of Δ9-THC: Exploration of Possible Biological Targets	18
The Marburg Virus Outbreak in West Africa	18

Thioethers: An Overview	17
Meet the Editorial Board Member	17
Proteasome as a Drug Target in Trypanosomatid Diseases	17
Fibrinolysis in COVID-19: Impact on Clot Lysis and Modulation of Inflammation	16
Therapeutic Potential of HDAC Inhibitors in the Treatment of Cardiac Diseases: A Short Review	16
Nanocarriers for Photodynamic Therapy Intended to Cutaneous Tumors	16
The Fate of Nanoparticles In Vivo and the Strategy of Designing Stealth Nanoparticle for Drug Delivery	16
Strategies and Therapies for Wound Healing: A Review	16
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	15
Oral Semaglutide in the Management of Type 2 DM: Clinical Status and Comparative Analysis	15
A Review on Nanotechnologically Derived Phytomedicines for the Treatment of Hepatocellular Carcinoma: Recent Advances in Molecular Mechanism and Drug Targeting	14
The Role of Glycolipids and their Toxicity in the Context of Nanomaterials and Nanoparticles: A Review of the Literature	14
A Review on the Recent Advancements and Artificial Intelligence in Tablet Technology	14
Revealing Insights into Natural Products Against mcr-1-Producing Bacteria	13
Recent Advances in Psoriasis Therapy: Trends and Future Prospects	13
Drug Repurposing Using FDA Adverse Event Reporting System (FAERS) Database	13
LncRNA HAGLROS: A Vital Oncogenic Propellant in Various Human Cancers	13
Nrf2 and Ferroptosis: Exploring Translational Avenues for Therapeutic Approaches to Neurological Diseases	13
In Vivo Models of Steroid-Induced Intraocular Hypertension	13
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	13
Endogenous Ligands of TLR4 in Microglia: Potential Targets for Related Neurological Diseases	13
SGK-1 Signalling Pathway is a Key Factor in Cell Survival in Ischemic Injury	12
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	12
HPV-mediated Cervical Cancer: A Systematic Review on Immunological Basis, Molecular Biology, and Immune Evasion Mechanisms	12
Prostaglandins in the Inflamed Central Nervous System: Potential Therapeutic Targets	12
Canonical Wnt/Beta-Catenin Signaling Network as Emerging Signaling Cascade for Therapeutic Intervention in Chronic Renal Disease	12
Comparative Analysis of Circular RNAs Expression and Function between Aortic and Intracranial Aneurysms	12
MiRNA, a New Treatment Strategy for Pulmonary Fibrosis	11
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	11
Free ISG15 and Protein ISGylation Emerging in SARS-CoV-2 Infection	11
Role of Poly(ADP-ribose) Polymerase (PARP1) in Viral Infection and its Implication in SARS-CoV-2 Pathogenesis	11
Cytotoxic Flavokawain B Inhibits the Growth and Metastasis of Hepatocellular Carcinoma through UCK2 Modulation of the STAT3/Hif-1α/VEGF Signalling Pathway	11
Targeted Treatment Strategies for Mitochondria Dysfunction: Correlation with Neurological Disorders	11
Estimating the Survival Rate in Glioblastoma Multiforme Patients who Received a Peptide Vaccine: A Systematic Review and Meta-analysis	11
N-Heterocycle based Degraders (PROTACs) Manifesting Anticancer Efficacy: Recent Advances	11
Current Research Trends in Cytokine Storm: A Scientometric Study	11
Targeting SERCA2 in Anti-Tumor Drug Discovery	11
Alzheimer's Disease and β-secretase Inhibition: An Update with a Focus on Computer-aided Inhibitor Design	11
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	11
Therapeutic Approaches for Combating Aspergillus Associated Infection	10
Anti-inflammatory Potential of GSK-3 Inhibitors	10
Revolutionizing the World of Pharmaceuticals: Unleashing the Game-Changing Power of 3D Printing	10
Clinical Combinatorial Treatments Based on Cancer Vaccines: Combination with Checkpoint Inhibitors and Beyond	10
GPR56, an Adhesion GPCR with Multiple Roles in Human Diseases, Current Status and Future Perspective	10
A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease	10
Role of ATP-binding Cassette Transporters in Sorafenib Therapy for Hepatocellular Carcinoma: An Overview	10
Exploring AT2R and its Polymorphism in Different Diseases: An Approach to Develop AT2R as a Drug Target beyond Hypertension	10
Microbubbles Contrast Agents: General Overview as Diagnostics and Therapeutic Agent	10
Long Non-coding RNA Therapeutics: Recent Advances and Challenges	9
Hybrid-Compounds Against Trypanosomiases	9

Recent Medicinal Chemistry Studies for Multitarget Agents-Part I	9
Mitochondrial Dysfunction in Huntington’s Disease: Pathogenesis and Therapeutic Opportunities	9
Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9
Withdrawal Notice: Obesity: A template to trigger metabolic syndromes and carcinoma. Metformin: A drug target	9
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	9
Meet the Regional Editor	9
The Extracapsular Lymph Node Extension Predicts Outcomes in Colorectal Cancer: A Short Review	9
Emerging Combinatorial Drug Delivery Strategies for Breast Cancer: A Comprehensive Review	8
Combinatory Approaches Targeting Cognitive Impairments and Memory Enhancement: A Review	8
Biological Potential and Therapeutic Effectiveness of Geiparvarin in Medicine for its Anti-proliferative Activity against Tumors and Other Human Complications	8
Corrigendum to: Can Medical Therapy Fix Sexual Dysfunction after Major Pelvic and Prostate Surgery and does it Work for Kidney Stones? Chemotherapy before Cystectomy, New Schemes for which Patients?	8
Meet the Editorial Board Member	8
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	8
Gastrointestinal System: COVID-19 and Potential Mechanisms Associated with Coagulopathy	8
Emerging Trends and Future Challenges of Nanovaccine Delivery via Nasal Route	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Pharmacological and Therapeutic Potential of a Natural Flavonoid Icariside II in Human Complication	8
Meet the Regional Editor	8
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	8
Target Genetic Abnormalities for the Treatment of Colon Cancer and Its Progression to Metastasis	8
Meet the Associate Editorial Board Member	8
To Explore the Potential Targets and Current Structure-based Design Strategies Utilizing Co-crystallized Ligand to Combat HCV	7
Tebentafusp as a Promising Drug for the Treatment of Uveal Melanoma	7
Meet the Editorial Board Member	7
The Emergence of Immune-checkpoint Inhibitors in Colorectal Cancer Therapy	7
Meet Our Editorial Board Member	7
Oxidative Stress: Meeting Multiple Targets in Pathogenesis of Vascular Endothelial Dysfunction	7
Recent Avenues in Treatment of Liver Diseases: Role of Nanotechnology	6
Meet the Editorial Board Member	6
Cisplatin-Based Combination Therapy for Enhanced Cancer Treatment	6
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	6
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	6
Biomimetic Drug Delivery Systems Oriented by Biological Function in Tumor Targeting	6
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	6
Gut Microbiota and Inflammatory Disorders	6
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	6
Meet the Editorial Board Member	6
Therapeutic Correlation of TLR-4 Mediated NF-κB Inflammatory Pathways in Ischemic Injuries	6
Phytoconstituents-Based Nanotherapeutic Approach for the Effective Management of Joint Inflammatory Condition: Arthritis	6
The (Pro)renin Receptor - A Regulatory Nodal Point in Disease Networks	6
Lung Pneumonitis and Fibrosis in Cancer Therapy: A Review on Cellular and Molecular Mechanisms	6