OOIR: Observatory of International Research

Papers

(The TQCC of Current Drug Targets is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Current Research Trends in Cytokine Storm: A Scientometric Study	39
Meet the Editorial Board Member	37
Cell Entry and Unusual Replication of SARS-CoV-2	36
Meet the Editorial Board Member	29
SARS-Coronavirus 2, A Metabolic Reprogrammer: A Review in the Context of the Possible Therapeutic Strategies	26
Unfurling the Potential of Antiviral Agents Aimed for RNA Virus Ailment	26
The Marburg Virus Outbreak in West Africa	25
Metformin: A Promising Antidiabetic Medication for Cancer Treatment	25
The Development of the Combination Drug Leukovir® Tablets for the Treatment of Multiple Sclerosis: A Comprehensive Review	24
The Emerging Landscape of LINC01123 in Cancer: Roles, Mechanisms, and Clinical Significance	23
Retracted: Meet the Editorial Board Member	23
Review on the Drug Intolerance and Vaccine Development for the Leishmaniasis	23
Polymeric Micelle-Based Nanogels as Emerging Drug Delivery Systems in Breast Cancer Treatment: Promises and Challenges	23
Meet the Regional Editor	22
Targeting Neurodegeneration: The Emerging Role of Hybrid Drugs	22
Targeted Delivery Strategies of Herbal-Based Nanogels: Advancements and Applications	22
Regulation of Tumor Immune Microenvironment by Sphingolipids and Lysophosphatidic Acid	21
Meet the Editorial Board Member	21
Xerostomia: Advances and Challenges in Drug Development	21
Use of Total Parenteral Nutrition (TPN) as a Vehicle for Drug Delivery	20
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach	19
Venom of Viperidae: A Perspective of its Antibacterial and Antitumor Potential	19
An Updated Review for the Diabetic Wound Healing Systems	19
Betaine, a Potential Therapeutic Alternative for the Treatment of Depression	19
Meet the Editorial Board Member	18

An Overview of Research Advances in Oncology Regarding the Transcription Factor ATF4	18
COVID-19 Induces Cytokine Storm and Dysfunctional Hemostasis	18
Lipid-based Nanocarriers Loaded with Taxanes for the Management of Breast Cancer: Promises and Challenges	17
An Updated Insight into Phytomolecules and Novel Approaches used in the Management of Breast Cancer	17
Bile Acid Application in Cell-Targeting for Molecular Receptors in Relation to Hearing: A Comprehensive Review	17
RMNet: An RNA m6A Cross-species Methylation Detection Method for Nanopore Sequencing	17
Targets Involved in the Pharmacology of Bothrops Snakebite: Statu Quo and Future Perspectives	16
Research Progress of PARP Inhibitor Monotherapy and Combination Therapy for Endometrial Cancer	16
Diabetic Nephropathy: Pathogenesis to Cure	16
Insights into the Mechanism of the Therapeutic Potential of Herbal Monoamine Oxidase Inhibitors in Neurological Diseases	16
The Novel Use of Lipids as Diagnostic Tools and Therapeutics in Cancer: Recent Insights and Challenges	14
Lipidomics as Tools for Finding Biomarkers of Intestinal Pathology: From Irritable Bowel Syndrome to Colorectal Cancer	14
Meet the Editorial Board Member	14
The Role of Leukocyte Immunoglobulin-Like Receptors Focusing on the Therapeutic Implications of the Subfamily B2	13
Does the Grape Products Intake has an Effect on Body Weight in Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials	13
A Comprehensive Insight on Pharmaceutical Co-crystals for Improvement of Aqueous Solubility	13
Innovations in Antimalarial Drug Discovery: New Targets and Leads	13
ClpP Peptidase as a Plausible Target for the Discovery of Novel Antibiotics	13
Rho Kinase (ROCK) Inhibitors for the Treatment of Glaucoma	13
Exploring the Efficient Natural Products for the Therapy of Parkinson’s Disease via Drosophila Melanogaster (Fruit Fly) Models	13
Mitochondria-Targeted Nanoformulations: New Therapeutic Strategies and Opportunities for Cancer Immunotherapy	13
Advanced Drug Delivery System for Management of Chronic Diabetes Wound Healing	12
Tachykinin Receptors and their Antagonists: Unraveling Their Role in Metabolic Disorders and Therapeutic Innovations	12
Transcription Factors in Brain Regeneration: A Potential Novel Therapeutic Target	12
Prospection of Microfluidics for Local Drug Delivery	12
IL-17 Antagonists as a Promising Therapeutic Modality for Hidradenitis Suppurativa	12
Multi-target Compounds against Trypanosomatid Parasites and Mycobacterium tuberculosis	12
Transcending Molecules: Paving the Way from Lab to Life in Drug Transport Innovation	12
Effect of Rotenone on the Neurodegeneration among Different Models	11
Phytovesicular Nanoconstructs for Advanced Delivery of Medicinal Metabolites: An In-Depth Review	11
Recent Advances in the Development of Alpha-Glucosidase and Alpha-Amylase Inhibitors in Type 2 Diabetes Management: Insights from In silico to In vitro Studies	11
Targeting Creatine and Creatine Kinase in Cancer: Exploring Potential Therapeutic Strategies	11
Recent Advances in Biomedical Applications of Mannans and Xylans	11
Potential Targets in Constipation Research: A Review	11
A Review on the Current Status of Homeopathy in the Clinical Manage-ment of Cancer	10
Emerging Role of Circular RNAs in Kidney Diseases in Nephrology	10
Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead	10
MiRNAs Overexpression and Their Role in Breast Cancer: Implications for Cancer Therapeutics	10
Meet the Editorial Board Member	10
RAAS Overactivation and Mitochondrial Damage Signaling as Key Players in Lethal COVID-19	10
Signaling Dynamics in Osteogenesis: Unraveling Therapeutic Targets for Bone Generation	10
The Recent Advances in the Function and Mechanism of Caveolin-1 in Retinal Neovascularization	10
Combination Therapy as a Strategy to Control Infections Caused by Multi-resistant Bacteria: Current Review	10
Co-Crystallization: A Novel Technique to Improvise the Pharmaceutical Characteristics of API’s	9
An Exploratory Review on the Hypoglycemic Action of Unani Anti-diabetic Drugs via Possible Modulation of Gut Microbiota	9
Exploring the SARS-Cov-2 Main Protease (Mpro) and RdRp Targets by Updating Current Structure-based Drug Design Utilizing Co-crystals to Combat COVID-19	9
Emerging Threats and Challenges of Monkeypox Virus: Exploration and Sensitivity	9
Targeted Covalent Inhibition: A Prospective Way to Develop Novel HSP90 C-terminal Inhibitor	9
Proteasome as a Drug Target in Trypanosomatid Diseases	9
Statin Therapy and C-reactive Protein in Patients with Kidney Disease: A Systematic Review and Meta-analysis of Randomized Clinical Trials	9

Advances in Understanding and Managing Alzheimer's Disease: From Pathophysiology to Innovative Therapeutic Strategies	9
A Review of Amylin Peptide Receptor Activators for Obesity Pharmacotherapy	8
Skin Microbial Composition and Genetic Mutation Analysis in Precision Medicine for Epidermolysis Bullosa	8
Diabetic Wound Healing: Factors, Mechanisms, and Treatment Strategies Using Herbal Components	8
Nanoformulations - Insights Towards Characterization Techniques	8
Sepsis-Associated Brain Dysfunction: Mechanisms, Clinical Insights, and Therapeutic Strategies	8
Advances in Cysteine Protease B Inhibitors for Leishmaniasis Treatment	8
Proteases and Osteoporosis: A Comprehensive Review of Their Role in Bone Health	8
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy	8
Multitarget Compounds for Neglected Diseases: A Review	8
Investigating the Mechanism of Astragalus mongholicus-Mediated Treatment of Silicosis in Mice from the Perspective of Alternative Splicing	8
Sodium-glucose Cotransporter 2 Inhibitors and Pathological Myocardial Hypertrophy	7
Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review	7
Meet the Associate Editorial Board Member	7
Vaccine for Targeted Therapy of Lung Cancer: Advances and Developments	7
Effects of Kefir Consumption on Cardiometabolic Risk Factors: A Systematic Review and Meta-analysis of Randomized Controlled Trials	7
Potential Implications of Angiotensin-converting Enzyme 2 Blockades on Neuroinflammation in SARS-CoV-2 Infection	7
Precision Targeting of BET Proteins - Navigating Disease Pathways, Inhibitor Insights, and Shaping Therapeutic Frontiers: A Comprehensive Review	7
Beneficial Outcomes of Cancer Therapeutic Modalities Based on Targeting Apoptosis	7
A Comprehensive Review on Chrysin: Emphasis on Molecular Targets, Pharmacological Actions and Bio-pharmaceutical Aspects	7
Acknowledgements to Reviewers	7
Differential Drug Permeability across Biofilms	7