Mini-Reviews in Medicinal Chemistry

Article	Citations
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer	114
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy	73
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects	69
Protein and Small-Molecule Leucopoiesis and Thrombopoiesis Stimulators	60
Natural Products Databases for Drug Design	51
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus	48
A Review on Rotenoids: Purification, Characterization and its Biological Applications	48
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives	45
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities	43
Aptamers Against COVID-19: An Untested Opportunity	42
Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review	41
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects	41
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease	41
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review	40
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease	39
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities	38
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes	36
Multi-Target Drug Design of Anti-Alzheimer’s Disease based on Tacrine	35
Meet the Editorial Board Member	34
Meet the Editorial Board Member	33
Meet the Editorial Board Member	33
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer	32
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome	31
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections	31
Meet the Editorial Board Member	30

Recent Advances in Natural Products with Antiviral Activities	27
Advances in Exercise Therapy in Hemodialysis: A Systematic Review	27
Anticancer Potential of Coumarin and its Derivatives	27
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach	27
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities	27
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells	27
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds	26
Associate Editorial Board Members	26
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry	26
Meet the Editorial Board Member	25
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease	23
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease	23
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy	22
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis	22
Meet the Section Editor	22
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives	22
The Role of MiR-29 in the Mechanism of Fibrosis	21
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors	21
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships	20
A Review on Acridines as Antiproliferative Agents	20
Natural Products with BACE1 and GSK3β Inhibitory Activity	20
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma	20
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections	20
Meet the Frontiers Section Editor	19
Ferulic Acid and Cardiovascular Health: Therapeutic and Preventive Potential	19
Role of TBK1 Inhibition in Targeted Therapy of Cancer	19
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer	19
Antioxidant, Anti-inflammatory, Antibacterial, and Analgesic Activities and Mechanisms of Quinolines, Indoles and Related Derivatives	19
Meet the Editorial Board Member	18
AGAP2-AS1: An Indispensable lncRNA in Tumors	18
Meet the Editorial Board Member	18
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review	18
Drug Solubilization by Surfactants: Experimental Methods and Theoretical Perspectives	18
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters	17
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities	17
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings	17
A Critical Review on Recent Development of Techniques and Drug Targets in the Management of Breast Cancer	17
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies	16
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors?	16
Adhatoda vasica (Nees.): A Review on its Botany, Traditional uses, Phytochemistry, Pharmacological Activities and Toxicity	16
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities	16
SET Protein in Cancer: A Potential Therapeutic Target	16
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review	16
Meet the Editorial Board Member	16
Recent Advances in the Development of Type 2 Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 2 Diabetes Mellitus	16
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective	15
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging	15
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy	15
Cholesterol: Bioactivities, Structural Modification, Mechanisms of Action, and Structure-Activity Relationships	15
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection	15

Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review	15
Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity	14
Meet the Editorial Board Member	14
Meet the Editorial Board Member	14
Meet the Editorial Board Member	14
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment	14
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease	14
Meet the Editor-in-Chief	14
Overview of the Biological Activities of Pyrimido[4,5-d]pyrimidines	13
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis	13
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts	13
Inhibitors Targeting Hepatitis C Virus (HCV) Entry	13
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative	13
Recent Updates on Sinularia Soft Coral	13
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential	13
Human Galectin-1 in Multiple Cancers: A Privileged Molecular Target in Oncology	13
Meet the Editorial Board Member	13
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters	13
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray	12
Strategies in Taxol Development: A Review	12
Meet the Editorial Board Member	12
Meet the Editorial Board Member	12
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications	12
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review	12
Meet the Editorial Board Member	12
Glycyrrhizin as a Potential Treatment for the Novel Coronavirus (COVID-19)	12
Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials	12
A Therapeutic Journey of Potential Drugs Against COVID-19	12
Meet the Editorial Board Member	12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors	12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review	12
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches	12
Origins, Structures, and Bioactivities of Secondary Metabolites from Marine-derived Penicillium Fungi	12
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics	12
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art	12
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades	12
The Application of the Pyrazole Structure in the Structural Modification of Natural Products	11
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer	11
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview	11
Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment	11
A Review on a Medicinal and Edible Plant: Aralia elata (Miq.) Seem.	11
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)	11
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review	11
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions	11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)	11
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms	11
Melatonin and Related Compounds as Antioxidants	11
The Search for Antidotes Against Ricin	11
Role of Cathepsin B in Cancer Progression: A Potential Target for Coordination Compounds	11
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry	11
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging	10
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review	10
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases	10
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)	10
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists	10
Some Scaffolds as Anti-leishmanial Agents: A Review	10
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil	10
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment	10
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications	10
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review	10
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review	10
Acknowledgements to Reviewers	10
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing	10
Agent in Urgent Need of Clinical Practice: Corilagin	10
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation	10
Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia	10
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications	10
Meet the Editorial Board Member	10
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects	10
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review	9
Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh2	9
Meet the Editorial Board Member	9
Meet the Editorial Board Member	9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment	9
Meet the Editor in Chief	9
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives	9
Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity	9
Meet the Co-Editor	9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways	9
Recent Progress Towards Vaccines and Antibody-based Therapies Against Alzheimer's Disease	9

PRISMA Based Systematic Review: Pharmacognostic Study of Zanthoxylum armatum DC.	9
A Short Review on Glucogallin and its Pharmacological Activities	9
Meet the Executive Guest Editor	9
An Updated Review of Various Medicinal Applications of p-Co umaric Acid: From Antioxidative and Anti-Inflammatory Properties to Effects on Cell Cycle and Proliferation	9
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K	9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis	9
Systematic Review of the Serotonergic System in the Pathophysiology of Severe Dengue: The Theory of Thrombocytopenia and Vascular Extravasation	8
Levothyroxine and Non-alcoholic Fatty Liver Disease: A Mini Review	8
Cathepsin B-A Neuronal Death Mediator in Alzheimer’s Disease Leading to Neurodegeneration	8
Fungal Endophytes: A Storehouse of Bioactive Compounds	8
Lyophilization of Molecular Biology Reactions: A Review	8
Comparative Review of Effects of Pien Tze Huang and AnGong NiuHuang Pill and their Potential on Treatment of Central Nervous System Diseases	8
ZFPM2-AS1: An Oncogenic Long Non-coding RNA in Multiple Cancer Types	8
Recent Advances in Fluorescent Probes for G-quadruplex DNAs / RNAs	8
The Use of Nanocarriers to Enhance the Anti-neuroinflammatory Potential of Dietary Flavonoids in Animal Models of Neurodegenerative Diseases: A Systematic Review	8
Recent Advances in Small Molecular PET Tracers for Pancreatic Cancer Diagnosis: Preclinical Stage	8
Elucidating the Drug Repurposing Spectra of COVID-19 with its Analogues SARS and MERS	8
Meet the Associate Editorial Board Member	8
Natural and Synthetic Phosphodiesterase Inhibitors in 2023: an Update on the Impact on Neurological and Psychiatric Conditions	8
The Emergence of N. sativa L. as a Green Antifungal Agent	8
Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism	8
Acknowledgements to Reviewers	8
LncRNA DSCAM-AS1: A Pivotal Therapeutic Target in Cancer	8
Bioactivities of Dietary Polyphenols and Their Effects on Intestinal Microbiota	8
Dendrobine: A neuroprotective Sesquiterpenic Alkaloid for the Prevention and Treatment of Diseases: A Review	8
Meet the Editorial Board Member	8
Biological Activities of Morita-Baylis-Hillman Adducts (MBHA)	8
Acknowledgement to Reviewers	8
Meet the Associate Editorial Board Member	8
An Updated and Focused Review on Heterocyclic Inhibitors for SARSCoV and SARS-CoV-2 3CLpro	8
Exploring Tetrahydroisoquinoline (THIQ) Scaffold as Therapeutic Modulators of Sigma Receptors	7
Promising Enzymes for Inhibitors Development Against COVID-19	7
Mitochondrial Proteins as Metabolic Biomarkers and Sites for Therapeutic Intervention in Primary and Metastatic Cancers	7
Effects of Green Tea (−)-Epigallocatechin-3-Gallate (EGCG) on Cardiac Function - A Review of the Therapeutic Mechanism and Potentials	7
Role of Caffeine in the Age-related Neurodegenerative Diseases: A Review	7
Brassica oleracea var. capitata f. alba: A Review on its Botany, Traditional uses, Phytochemistry and Pharmacological Activities	7
Alzheimer's Disease and Cancer: Common Targets	7
The Role of Epigenetic Mechanisms in Autoimmune, Neurodegenerative, Cardiovascular, and Imprinting Disorders	7
Mini-Review on Vitamin D in Pediatric Population and its Role in Respiratory and Atopic Disorders	7
A New Mode of Thinfilm and Nanofiber for Burst Release of the Drug for Alzheimer Disease; A Complete Scenario from Dispersible Polymer to Formulation Methodology	7
Therapeutic Potential of Thiophene Compounds: A Mini-Review	7
The Role of 3'UTR of RNA Viruses on mRNA Stability and Translation Enhancement	7
The Role of Renin-Angiotensin System in Diabetic Nephropathy: An Update	7
Meet the Section Editor	7
Selenium and Computational Studies	7
Phage-choline Kinase Inhibitor Combination to Control Pseudomonas aeruginosa: A Promising Combo	7
Meet the Editorial Board Member	7
Research Progress of Tamarixetin and its Glycosides	7
Pyridine Moiety: An Insight into Recent Advances in the Treatment of Cancer	7
Exploration of Potent Multi-target-directed-ligands as Anti-alzheimer’s Disease Agents: A Moiety Based Review	6
1,3,5-Triazine: Recent Development in Synthesis of its Analogs and Biological Profile	6
Meet the Editorial Board Member	6
Cytotoxic Activity of Tropane Alkaloides of Species of Erythroxylum	6
A Review and Meta-analysis on Trastuzumab Resistance in Patients with HER2+ Breast Cancer	6
Tuberculosis, BCG Vaccination, and COVID-19: Are They Connected?	6
Preface	6
Chitosan: Applications in Drug Delivery System	6
Recent Progress of Bioactivities, Mechanisms of Action, Total Synthesis, Structural Modifications and Structure-activity Relationships of Indole Derivatives: A Review	6
Acknowledgements to Reviewers	6
Withdrawal: Advances in Development of Drugs for Chronic Myelogenous Leukemia	6
Osthole: Synthesis, Structural Modifications, and Biological Properties	6
Developments in the Antitumor Activity, Mechanisms of Action, Structural Modifications, and Structure-Activity Relationships of Steroidal Saponins	6
Exploring Genetic Silencing: RNAi and CRISPR-Cas Potential against Drug Resistance in Malaria	6
Anti-aging Natural Compounds and their Role in the Regulation of Metabolic Pathways Leading to Longevity	6
Recent Development of DNA Gyrase Inhibitors: An Update	6
Research Progress on the Natural Product Aloperine and Its Derivatives	6
MiRNAs: Emerging Agents for Therapeutic Effects of Polyphenols on Ovarian Cancer	6
Antidiabetic Properties of Dietary Chrysin: A Cellular Mechanism Review	6
In silico Approaches for Exploring the Pharmacological Activities of Benzimidazole Derivatives: A Comprehensive Review	6
Biodegradable Polymers and their Applications: A Review	6
Gastrointestinal, Liver, Pancreas, Oral and Psychological Long-term Symptoms of COVID-19 After Recovery: A Review	6
A Concise and Useful Guide to Understand How Alpha1 Adrenoceptor Antagonists Work	6
The Progress of Small Molecule Targeting BCR-ABL in the Treatment of Chronic Myeloid Leukemia	6
2-Substituted-mercapto-quinazolin-4(3H)-ones as DHFR Inhibitors	6
SARS-CoV-2 Infections, Impaired Tissue, and Metabolic Health: Pathophysiology and Potential Therapeutics	6
Nano-biotechnology and its Innovative Perspective in Diabetes Management	6
Nuclear Medicine Application of Pentixafor/Pentixather Targeting CXCR4 for Imaging and Therapy in Related Disease	6
Cyclin-Dependent Kinase 4/6 Inhibitors Against Breast Cancer	6
Emerging Role of Terpenoids for the Treatment of Cancer: A Review	6
Meet the Section Editor	6
Electrospinning: New Strategies for the Treatment of Skin Melanoma	5
An In Silico Approach to Exploring the Antinociceptive Biological Activities of Linalool and its Metabolites	5
An Outline on Benzimidazole Containing Marketed Drugs with Proton Pump Inhibitor and H1 Receptor Antagonist Activities	5
Meet the Editorial Board Member	5
Synthetic Attempts Towards Eminent Anti-viral Candidates of SARS-CoV	5
Treatment Approaches for COVID-19: A Critical Review	5
Pharmaceutical Studies on Piperazine-based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters	5
The Immune Response to SARS-CoV-2: Mechanisms, Aging, Sequelae, and Vaccines	5
Coronavirus (COVID - 19): Chemical Entities of Biological Interest	5
The Role of Essential Oils on Sleep Quality and Other Sleep-related Issues: Evidence from Clinical Trials	5
A Review on Remdesivir: A Broad-spectrum Antiviral Molecule for Possible COVID-19 Treatment	5
Distinct Modulation of Wild-Type and Selective Gene Mutated Vitamin D Receptor by Essential Polyunsaturated Fatty Acids	5
Nature-Derived Hit, Lead, and Drug-Like Small Molecules: Current Status and Future Aspects Against Key Target Proteins of Coronaviruses	5
Meet the Editorial Board Member	5
Research and Progress of Probucol in Nonalcoholic Fatty Liver Disease	5