Mini-Reviews in Medicinal Chemistry

Papers
(The TQCC of Mini-Reviews in Medicinal Chemistry is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Meet the Section Editor100
Synthetic Approaches and Pharmacological Attributes of Benzosuberone Skeleton63
The Progress of Small Molecule Targeting BCR-ABL in the Treatment of Chronic Myeloid Leukemia59
Withdrawal: Advances in Development of Drugs for Chronic Myelogenous Leukemia56
Meet the Editorial Board Member53
Sustainable Synthesis of Medicinally Important Heterocycles52
The Application of the Pyrazole Structure in the Structural Modification of Natural Products51
Cytotoxic Activity of Tropane Alkaloides of Species of Erythroxylum48
Recent Progress and Perspectives in Sodium-Glucose Co-transporter 1/2 Inhibitors46
Therapeutic Potental of Quinolin-2H-one Hybrids as Anticancer Agents45
Meet Our Editorial Board Member42
Acknowledgements to Reviewers39
Meet Our Editorial Board Member39
Chemical Synthesis of Selenium-containing Peptides38
Meet the Section Editor38
Natural Products Databases for Drug Design37
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview37
Protein and Small-Molecule Leucopoiesis and Thrombopoiesis Stimulators37
Meet the Editorial Board Member37
Meet the Editorial Board Member36
Roles of lncRNA-MALAT1 in the Progression and Prognosis of Gliomas33
Cyclin-Dependent Kinase 4/6 Inhibitors Against Breast Cancer32
Meet the Editorial Board Member31
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease31
Therapeutic Potential of Resveratrol in the Treatment of Glioma: Insights into its Regulatory Mechanisms30
A Systematic Review of Machine Learning Based Gait Characteristics in Parkinson’s Disease30
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review29
Review on Characteristics and Analytical Methods of Remogliflozin Etabonate: An Update28
Meet the Editorial Board Member28
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects27
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review26
Targeting Glioma Cells with Nutraceuticals: Therapeutic Effects Based on Molecular Mechanisms, New Evidence and Perspectives26
Meet the Editorial Board Member24
Purinergic Signaling and its Role in the Stem Cell Differentiation24
DNA Interaction and Cytotoxic studies on Mono/Di-Oxo and Peroxo- Vanadium (V) complexes - A Review23
Anti-mycobacterial Constituents from Medicinal Plants; A Review23
Aptamers Against COVID-19: An Untested Opportunity23
Meet the Executive Guest Editor22
Meet the Editorial Board Member22
Mechanism of Natural Drugs on Nonalcoholic Fatty Liver Disease22
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives22
MiRNAs: Emerging Agents for Therapeutic Effects of Polyphenols on Ovarian Cancer21
Meet the Editorial Board Member20
Meet the Editorial Board Member20
Meet the Editorial Board Member20
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art19
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities18
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review18
Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review18
A Review on Rotenoids: Purification, Characterization and its Biological Applications17
From Traditional Use to Modern Evidence: The Medicinal Chemistry of Antimalarials from Genus Artemisia17
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs): A Review17
The Most Recent Discoveries in Heterocyclic Nanoformulations for Targeted Anticancer Therapy17
Meet the Frontier Section Editor17
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray17
2-Substituted-mercapto-quinazolin-4(3H)-ones as DHFR Inhibitors16
Insight into the Synthesis, Biological Activity, and Structure-activity Relationship of Benzothiazole and Benzothiazole-hydrazone Derivatives: A Comprehensive Review16
In silico Approaches for Exploring the Pharmacological Activities of Benzimidazole Derivatives: A Comprehensive Review16
Multi-vesicular Liposome and its Applications: A Novel Chemically Modified Approach for Drug Delivery Application16
Targeting STAT3 Enzyme for Cancer Treatment16
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications16
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease15
A Comprehensive Review of Garcinia pedunculata Roxb. and its Therapeutic Potential15
Bioactive Furanyl- or Thienyl-Substituted Nucleobases, Nucleosides and Their Analogues15
Antidiabetic Properties of Dietary Chrysin: A Cellular Mechanism Review15
Immunotherapy in Combination with Chemotherapy for Triple-negative Breast Cancer15
Toward Early Diagnosis of Colorectal Cancer: Focus on Optical Nano Biosensors15
Hypericin Ameliorates Maternal Separation-Induced Cognitive Deficits and Hippocampal Inflammation in Rats14
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy14
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades14
Structure, Biological Activities and Metabolism of Flavonoid Glucuronides14
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review14
Nanomaterials for Deep Tumor Treatment14
Recent Developments in Shape-Controlled Synthesis of Cellulose Nanocrystals13
A Therapeutic Journey of Potential Drugs Against COVID-1913
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics13
Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment13
The Advances in Bioactivities, Mechanisms of Action and Structural Optimizations of Matrine and its Derivatives13
Exploration of Potent Multi-target-directed-ligands as Anti-alzheimer’s Disease Agents: A Moiety Based Review12
Thrombin - A Molecular Dynamics Perspective12
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects12
Nuclear Medicine Application of Pentixafor/Pentixather Targeting CXCR4 for Imaging and Therapy in Related Disease12
Synthetic Methods of Quinoxaline Derivatives and their Potential Anti-inflammatory Properties12
Diabetes Pharmacotherapy and its effects on the Skeletal Muscle Energy Metabolism12
Chitosan: Applications in Drug Delivery System11
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms11
The Role of LncRNA TUG1 in Obesity-related Diseases11
Review of 10,11-Dehydrocurvularin: Synthesis, Structural Diversity, Bioactivities and Mechanisms11
The Effects of Apigenin in the Treatment of Diabetic Nephropathy: A Systematic Review of Non-clinical Studies11
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus11
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer11
Chemistry and Reactivity of 4-hydroxy-2-nonenal (HNE) in Model Biological Systems11
Recent Progress of Bioactivities, Mechanisms of Action, Total Synthesis, Structural Modifications and Structure-activity Relationships of Indole Derivatives: A Review11
Anti-aging Natural Compounds and their Role in the Regulation of Metabolic Pathways Leading to Longevity11
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions11
Role of Cathepsin B in Cancer Progression: A Potential Target for Coordination Compounds11
A Review on a Medicinal and Edible Plant: Aralia elata (Miq.) Seem.11
Antimicrobial Properties of Mandelic Acid, Gallic Acid and their Derivatives10
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities10
Melatonin and Related Compounds as Antioxidants10
Recent Applications of Azo Dyes: A Paradigm Shift from Medicinal Chemistry to Biomedical Sciences10
Multi-Target Drug Design of Anti-Alzheimer’s Disease based on Tacrine10
CRISPR-Cas9 Genome Engineering: Trends in Medicine and Health10
Fenugreek Cultivation with Emphasis on Historical Aspects and its uses in Traditional Medicine and Modern Pharmaceutical Science10
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes10
Development of Natural Bioactive Alkaloids: Anticancer Perspective10
The Search for Antidotes Against Ricin10
Research Mechanism and Progress of the Natural Compound Curcumin in Treating Alzheimer´s Disease10
Recent Progress in Anticancer Agents Incorporating Pyrazole Scaffold10
Tanshinone IIA Against Cerebral Ischemic Stroke and Ischemia- Reperfusion Injury: A Review of the Current Documents10
Virtual Screening of Natural Products Database10
Recent Advancements on Benzimidazole: A Versatile Scaffold in Medicinal Chemistry10
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors10
Quinoline: An Attractive Scaffold in Drug Design10
Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia10
Preface10
Meet the Editorial Board Member9
Targeting of ErbB1, ErbB2, and their Dual Targeting Using Small Molecules and Natural Peptides: Blocking EGFR Cell Signaling Pathways in Cancer: A Mini-Review9
Innovative Theranostics Strategies in the Fight Against Lung Cancer9
The Zinc-dependent HDACs: Non-histone Substrates and Catalytic Deacylation Beyond Deacetylation9
Meet the Editorial Board Member9
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review9
Meet the Editorial Board Member9
Neuroendocrinological and Clinical Aspects of Leptin9
S-adenosyl-L-homocysteine Hydrolase: Its Inhibitory Activity Against Plasmodium falciparum and Development of Malaria Drugs9
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach9
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications9
Quantum Dots as Theranostic Agents: Recent Advancements, Surface Modifications, and Future Applications9
Advances in Pyrazole Based Scaffold as Cyclin-dependent Kinase 2 Inhibitors for the Treatment of Cancer9
Natural Bridged Bicyclic Peptide Macrobiomolecules from Celosia argentea and Amanita phalloides8
A Review on Therapeutic Strategies against Parkinson’s Disease: Current Trends and Future Perspectives8
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases8
Meet the Editor-in-Chief8
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells8
Methyl-linked Pyrazoles: Synthetic and Medicinal Perspective8
Recent Development of DNA Gyrase Inhibitors: An Update8
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities8
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review8
Poly(ADP-Ribose) Polymerase-1 Inhibitors Drug Discovery, Design, and Development as Anticancer Agents from Past to Present: A Mini-Review8
Comprehensive Review on Recent Strategies for Management of Prostate Cancer: Therapeutic Targets and SAR8
The Roles of Cytoplasmic Polyadenylation Element Binding Protein 1 in Tumorigenesis8
A Mini Review on Emerging Targets and Approaches for the Synthesis of Anti-viral Compounds: In Perspective to COVID-198
Meet the Editorial Board Member8
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry8
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)8
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing8
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections8
Plant Based Natural Products as Quorum Sensing Inhibitors in E. Coli: A Critical Review8
Meet the Editorial Board Member8
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds8
Insight in Quinazoline-based HDAC Inhibitors as Anti-cancer Agents8
Molecular Dynamics Simulations in Drug Discovery8
Nano-biotechnology and its Innovative Perspective in Diabetes Management8
A Panoramic Review of Benzimidazole Derivatives and their Potential Biological Activity7
Structure-property Relationships Reported for the New Drugs Approved in 20237
Emerging Need of Today: Significant Utilization of Various Databases and Softwares in Drug Design and Development7
Small-Molecule Drugs in Immunotherapy7
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry7
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation7
The Recent Developments of ADCs with the Tubulysins as the Payloads7
Targeted Inhibition of the PI3K/Akt/mTOR Signaling Axis: Potential for Sarcoma Therapy7
Oncopreventive and Oncotherapeutic Potential of Licorice Chalcone Compounds: Molecular Insights7
SARS-CoV-2 Infections, Impaired Tissue, and Metabolic Health: Pathophysiology and Potential Therapeutics7
The Role of EGCG in Breast Cancer Prevention and Therapy.7
Anti-Tubercular Activity of Pyrazinamide Conjugates: Synthesis and Structure-Activity Relationship Studies7
A Rapid Qualitative Review of Sarcoidosis: Clinical Manifestations, Immunopathogenesis, Diagnosis and Treatment7
Clinical Utility of Soluble CD163 and its Diagnostic and Prognostic Value in a Variety of Neurological Disorders7
Research Progress on the Natural Product Aloperine and Its Derivatives7
Recent Progress in Andrographolide Derivatization: Structural Modification and Biological Activity7
Research Progress of Essential Oil as a New Complementary Therapy in the Treatment of Depression7
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer7
The Rising Risk of Chronic Kidney Disease (CKD) and How it is Dealt with: A Review of Current and Potential Phosphate Binders (PB)7
New Scope of Targeted Therapies in Lung Carcinoma7
Potential Epigenetic Targets for Combating Alzheimer’s Disease7
An Insight into the Polymeric Nanoparticles Applications in Diabetes Diagnosis and Treatment7
Targeting Ion Channels for the Treatment of Glioma7
A Review and Meta-analysis on Trastuzumab Resistance in Patients with HER2+ Breast Cancer7
Progress in Research on CNPY2 in Diseases7
Microbial Metabolites-induced Epigenetic Modifications for Inhibition of Colorectal Cancer: Current Status and Future Perspectives7
Advances on the Anti-Inflammatory Activity of Oleanolic Acid and Derivatives7
Current Biomedical and Diagnostic Applications of Gold Micro and Nanoparticles7
Tuberculosis, BCG Vaccination, and COVID-19: Are They Connected?7
ROR1-AS1: A Meaningful Long Noncoding RNA in Oncogenesis7
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