Mini-Reviews in Medicinal Chemistry

Papers
(The TQCC of Mini-Reviews in Medicinal Chemistry is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Targeting Lysosomes: A Strategy Against Chemoresistance in Cancer114
The Role of IL-6 Released During Exercise to Insulin Sensitivity and Muscle Hypertrophy73
A Review on Chemical Structures and Biological Activities of Dopamine Derivatives from Medicinal Insects69
Protein and Small-Molecule Leucopoiesis and Thrombopoiesis Stimulators60
Natural Products Databases for Drug Design51
A Review on Rotenoids: Purification, Characterization and its Biological Applications48
An Insight into the Combat Strategies for the Treatment of Type 2 Diabetes Mellitus48
Comprehensive Update on Synthetic Aspects of Bosentan Derivatives45
Quinoxaline: A Chemical Moiety with Spectrum of Interesting Biological Activities43
Aptamers Against COVID-19: An Untested Opportunity42
Recent Developments in Tacrine-based Hybrids as a Therapeutic Option for Alzheimer’s Disease41
Multitarget Directed Ligand Approaches for Alzheimer’s Disease: A Comprehensive Review41
Benefits of Manuka Honey in the Management of Infectious Diseases: Recent Advances and Prospects41
Synthetic Approach to Potential Anticancer Benzimidazole Derivatives: A Review40
Ferroptosis Inhibitors as Potential New Therapeutic Targets for Cardiovascular Disease39
Current Perspective of Synthesis of Medicinally Relevant Benzothiazole based Molecules: Potential for Antimicrobial and Anti-Inflammatory Activities38
Current Insight on the Role of Glucokinase and Glucokinase Regulatory Protein in Diabetes36
Multi-Target Drug Design of Anti-Alzheimer’s Disease based on Tacrine35
Meet the Editorial Board Member34
Meet the Editorial Board Member33
Meet the Editorial Board Member33
KRAS Pathway-based Therapeutic Approaches in Pancreatic Cancer32
Chemotherapeutic Strategies for Combating Staphylococcus aureus Infections31
Irisin and Energy Metabolism and the Role of Irisin on Metabolic Syndrome31
Meet the Editorial Board Member30
Anticancer Potential of Coumarin and its Derivatives27
Bioactive Flavonoids: A Comparative Overview of the Biogenetic and Chemical Synthesis Approach27
Bioactive Sulfonamides Derived from Amino Acids: Their Synthesis and Pharmacological Activities27
The Critical Function of microRNAs in Developing Resistance against 5- Fluorouracil in Cancer Cells27
Recent Advances in Natural Products with Antiviral Activities27
Advances in Exercise Therapy in Hemodialysis: A Systematic Review27
Revolutionizing Playing with Skeleton Atoms: Molecular Editing Surgery in Medicinal Chemistry26
The most Recent Compilation of Reactions of Enaminone Derivatives with various Amine Derivatives to Generate Biologically Active Compounds26
Associate Editorial Board Members26
Meet the Editorial Board Member25
Cinnamic Acid Derivatives: Recent Discoveries and Development Strategies for Alzheimer’s Disease23
Recent Advancements in Strategies for Abnormal Protein Clearance in Alzheimer's Disease23
Inhibitory Activities of Pyrazolo-Oxazine Heterocyclic Derivatives22
Molecular Insights on the Therapeutic Effect of Selected Flavonoids on Diabetic Neuropathy22
The Pivotal Function of SLC16A1 and SLC16A1-AS1 in Cancer Progress: Molecular Pathogenesis and Prognosis22
Meet the Section Editor22
Medicinal Plants in Cancer Treatment: Contribution of Nuclear Factor- Kappa B (NF-kB) Inhibitors21
The Role of MiR-29 in the Mechanism of Fibrosis21
Recent Advances in Nanobiotechnology for the Treatment of Non-Hodgkin’s Lymphoma20
Pharmacological Efficacy and Safety of Glycyrrhiza glabra in the Treatment of Respiratory Tract Infections20
Overview of Piperine: Bioactivities, Total Synthesis, Structural Modification, and Structure-Activity Relationships20
A Review on Acridines as Antiproliferative Agents20
Natural Products with BACE1 and GSK3β Inhibitory Activity20
Antioxidant, Anti-inflammatory, Antibacterial, and Analgesic Activities and Mechanisms of Quinolines, Indoles and Related Derivatives19
Meet the Frontiers Section Editor19
Ferulic Acid and Cardiovascular Health: Therapeutic and Preventive Potential19
Role of TBK1 Inhibition in Targeted Therapy of Cancer19
Research Progress in Alpha-fetoprotein-induced Immunosuppression of Liver Cancer19
Meet the Editorial Board Member18
Quinoline Derivatives as Promising Scaffolds for Antitubercular Activity: A Comprehensive Review18
Drug Solubilization by Surfactants: Experimental Methods and Theoretical Perspectives18
Meet the Editorial Board Member18
AGAP2-AS1: An Indispensable lncRNA in Tumors18
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities17
Exploring the Therapeutic Potential of Green Tea (Camellia sinensis L.) in Anti-Aging: A Comprehensive Review of Mechanisms and Findings17
A Critical Review on Recent Development of Techniques and Drug Targets in the Management of Breast Cancer17
Roles of Accelerated Molecular Dynamics Simulations in Predictions of Binding Kinetic Parameters17
Development of Mycobacterium tuberculosis Enoyl Acyl Reductase (InhA) Inhibitors: A Mini-Review16
Meet the Editorial Board Member16
Recent Advances in the Development of Type 2 Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 2 Diabetes Mellitus16
Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies16
Quinoxaline 1,4-di-N-Oxide Derivatives: Are They Unselective or Selective Inhibitors?16
Adhatoda vasica (Nees.): A Review on its Botany, Traditional uses, Phytochemistry, Pharmacological Activities and Toxicity16
Recent Literature on the Synthesis of Thiazole Derivatives and their Biological Activities16
SET Protein in Cancer: A Potential Therapeutic Target16
The Effects of Increased Glucose Level and Glycolysis on SARS CoV-2 Infection15
Flavonoid-metal ion Complexes as Potent Anticancer Metallodrugs: A Comprehensive Review15
N-Methyl-D-Aspartate (NMDA)-Type Glutamate Receptors and Demyelinating Disorders: A Neuroimmune Perspective15
Current Status of and Perspectives on Radiolabelled Ubiquicidin 29-41 Derivatives for Bacterial Infection Imaging15
MicroRNAs and Efferocytosis: Implications for Diagnosis and Therapy15
Cholesterol: Bioactivities, Structural Modification, Mechanisms of Action, and Structure-Activity Relationships15
Drug Repurposing: A Conduit to Unravelling Metabolic Reprogramming for Cancer Treatment14
The Utilization and Development of Viral Vectors in Vaccines as a Prophylactic Treatment Against Ebola Virus as an Emerging and Zoonotic Infectious Disease14
Meet the Editor-in-Chief14
Curcumin: An Insight into Molecular Pathways Involved in Anticancer Activity14
Meet the Editorial Board Member14
Meet the Editorial Board Member14
Meet the Editorial Board Member14
An Overview of Pyridazinone Analogs: Chemical and Pharmacological Potential13
A Comprehensive Review on Chemistry and Biology of Tafamidis in Transthyretin Amyloidosis13
The Complex Roles of DNA Repair Pathways, Inhibitors, Hyperthermia, and Contact Inhibition in Cell Cycle Halts13
Chemical Strategies Toward Prodrugs and Fluorescent Probes for Gasotransmitters13
Overview of the Biological Activities of Pyrimido[4,5-d]pyrimidines13
Recent Updates on Sinularia Soft Coral13
Inhibitors Targeting Hepatitis C Virus (HCV) Entry13
Comprehensive Insight into Green Synthesis Approaches, Structural Activity Relationship, and Therapeutic Potential of Pyrazolic Chalcone Derivative13
Human Galectin-1 in Multiple Cancers: A Privileged Molecular Target in Oncology13
Meet the Editorial Board Member13
Origins, Structures, and Bioactivities of Secondary Metabolites from Marine-derived Penicillium Fungi12
Uncovering the Potential of Lipid Drugs: A Focus on Transient Membrane Microdomain-targeted Lipid Therapeutics12
Second-line Therapy for Helicobacter Pylori Eradication: State of the Art12
A Critical Observation on the Design and Development of Reported Peptide Inhibitors of DENV NS2B-NS3 Protease in the Last Two Decades12
The Therapeutic Potential and Molecular Mechanisms Underlying the Neuroprotective Effects of Sativex® - A Cannabis-derived Spray12
Strategies in Taxol Development: A Review12
Meet the Editorial Board Member12
Meet the Editorial Board Member12
The Situation of Small Molecules Targeting Key Proteins in combatting SARS-CoV-2: Synthesis, Metabolic Pathway, Mechanism of Action, and Potential Therapeutic Applications12
Chemistry, Analysis, and Biological Aspects of Daprodustat, A New Hypoxia Inducible Factor Prolyl Hydroxylase Inhibitor: A Comprehensive Review12
Meet the Editorial Board Member12
Glycyrrhizin as a Potential Treatment for the Novel Coronavirus (COVID-19)12
Effects of Urtica dioica on Metabolic Profiles in Type 2 Diabetes: A Systematic Review and Meta-analysis of Clinical Trials12
A Therapeutic Journey of Potential Drugs Against COVID-1912
Meet the Editorial Board Member12
Energy Metabolism Behavior and Response to Microenvironmental Factors of the Experimental Cancer Cell Models Differ from that of Actual Human Tumors12
Indole-3-carbinol (I3C) as Leukemia Therapeutic Agents: Review12
Therapeutic Potentials of Aconite-like Alkaloids: Bioinformatics and Experimental Approaches12
The Application of the Pyrazole Structure in the Structural Modification of Natural Products11
Nuclei-targeted Therapeutic Delivery: A Novel Concept for the Treatment of Cancer11
Radical Releasing Anti-tuberculosis Agents and the Treatment of Mycobacterial Tuberculosis Infections - An Overview11
Xanthone: Potential Acetylcholinesterase Inhibitor for Alzheimer's Disease Treatment11
A Review on a Medicinal and Edible Plant: Aralia elata (Miq.) Seem.11
In vivo Pharmacokinetic and ADMET Profiles of Synthetic Antimicrobial Peptides (AMPs)11
Chlorogenic Acid Derivatives: Structural Modifications, Drug Design, and Biological Activities: A Review11
Use of Chitosan as a Precursor for Multiple Applications in Medicinal Chemistry: Recent Significant Contributions11
The Role of Genetics and Synergistic Effect of Targeting Common Genetic Mutations in Acute Lymphoblastic Leukemia (ALL)11
Therapeutic Approaches for the Treatment of Interstitial Lung Disease: An Exploratory Review on Molecular Mechanisms11
Melatonin and Related Compounds as Antioxidants11
The Search for Antidotes Against Ricin11
Role of Cathepsin B in Cancer Progression: A Potential Target for Coordination Compounds11
Nutraceuticals, a Bridge Between Past and Future: Focus on Mushrooms Biological Activities and Myco-Chemistry11
Novel Niacin Receptor Agonists: A Promising Strategy for the Treatment of Dyslipidemia10
Aloe-emodin: Progress in Pharmacological Activity, Safety, and Pharmaceutical Formulation Applications10
Meet the Editorial Board Member10
Modulation of Long Non-coding RNAs by Different Classes of Secondary Metabolites from Plants: A Mini-review on Antitumor Effects10
Nicotinamide Adenine Dinucleotide in the Development and Treatment of Cardiac Remodeling and Aging10
New Insights into the Modifications and Bioactivities of Indole-3- Carboxaldehyde and its Derivatives as a Potential Scaffold for Drug Design: A Mini-Review10
The Role of VD/VDR Signaling Pathway in Autoimmune Skin Diseases10
Recent Insights of Metformin on Hepatocellular Carcinoma (HCC)10
Narrative Review of the Pharmacodynamics, Pharmacokinetics, and Toxicities of Illicit Synthetic Cannabinoid Receptor Agonists10
Some Scaffolds as Anti-leishmanial Agents: A Review10
Protective Effect of Plumeria Pudica Latex Proteins on Intestinal Mucositis Induced by 5-Fluorouracil10
Targeting Bcl-2 with Indole Scaffolds: Emerging Drug Design Strategies for Cancer Treatment10
Exploring the Versatility of Azine Derivatives: A Comprehensive Review on Synthesis and Biological Applications10
Antioxidant Activity of 1,2,4-Triazole and its Derivatives: A Mini-Review10
Recent Advancements and SAR Studies of Synthetic Coumarins as MAO-B Inhibitors: An Updated Review10
Acknowledgements to Reviewers10
Evaluation of Melatonin and its Nanostructures Effects on Skin Disorders Focused on Wound Healing10
Agent in Urgent Need of Clinical Practice: Corilagin10
Anthriscus sylvestris: An overview on Bioactive Compounds and Anticancer Mechanisms from a Traditional Medicinal Plant to Modern Investigation10
Peroxisome Proliferator-activated Receptor-γ As A Novel and Promising Target For Treating Cancer Via Regulation of Inflammation: A Brief Review9
Advances in Biocatalytic Synthesis, Pharmacological Activities, Pharmaceutical Preparation and Metabolism of Ginsenoside Rh29
Meet the Editorial Board Member9
Meet the Editorial Board Member9
Pharmacological Modulation of Apoptosis and Autophagy in Pancreatic Cancer Treatment9
Meet the Editor in Chief9
Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives9
Chromone, A Privileged Scaffold in Drug Discovery: Developments in the Synthesis and Bioactivity9
Meet the Co-Editor9
MCM3AP-AS1: A LncRNA Participating in the Tumorigenesis of Cancer Through Multiple Pathways9
Recent Progress Towards Vaccines and Antibody-based Therapies Against Alzheimer's Disease9
PRISMA Based Systematic Review: Pharmacognostic Study of Zanthoxylum armatum DC.9
A Short Review on Glucogallin and its Pharmacological Activities9
Meet the Executive Guest Editor9
An Updated Review of Various Medicinal Applications of p-Co umaric Acid: From Antioxidative and Anti-Inflammatory Properties to Effects on Cell Cycle and Proliferation9
Recent Studies on the Pharmacological Activities and Structural Modifications of Compound-K9
The Indispensable Roles of GMDS and GMDS-AS1 in the Advancement of Cancer: Fucosylation, Signal Pathway and Molecular Pathogenesis9
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