Biogerontology

Article	Citations
The crosstalk between CNS resident glial cells and peripheral immune cells is critical for age-dependent demyelination and subsequent remyelination	121
Prematurely aging female mice improve their behavioural response, immunity, redox state, and lifespan after a short social interaction with non-prematurely aging mice	91
Gut microbiota influence frailty syndrome in older adults: mechanisms and therapeutic strategies	59
Bridging expectations and science: a roadmap for the future of longevity interventions	57
First-generation versus next-generation epigenetic aging clocks: Differences in performance and utility	48
Cytoskeleton-associated protein 4: a double-edged sword in cell growth and aging	46
Beyond balance: the impact of adult sex ratios on reproduction and longevity in Zophobas morio rearing	37
Transcriptional activation of genes associated with the matrisome is a common feature of senescent endothelial cells	34
No strong association among epigenetic modifications by DNA methylation, telomere length, and physical fitness in biological aging	33
Forkhead box P1 transcriptionally activates IGF-1 to lighten ox-LDL-induced endothelial cellular senescence by inactivating NLRP3 inflammasome	31
Long-term dietary restriction ameliorates ageing-related renal fibrosis in male mice by normalizing mitochondrial functions and autophagy	29
Retraction Note to: Carbohydrate-restricted diet promotes skin senescence in senescence-accelerated prone mice	29
Roles of genistein in learning and memory during aging and neurological disorders	28
Empagliflozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress	28
Advancements in the investigation of the mechanisms underlying cognitive aging	27
Immune genes involved in synaptic plasticity during early postnatal brain development contribute to post-stroke damage in the aging male rat brain	26
Ufuk Çakatay (editor): Redox Signaling and Biomarkers in Ageing	25
Proteostasis networks in aging: novel insights from text-mining approaches	25
Swimming exercise with l-arginine coated nanoparticles supplementation upregulated HAND2 and TBX5 expression in the cardiomyocytes of aging male rats	23
Investigating the aging-modulatory mechanism of Rasayana Churna, an Ayurvedic herbal formulation, using a computational approach	22
Insights on the role of l-lactate as a signaling molecule in skin aging	22
Reproduction and preference to macronutrients have different relations to biological or chronological age in Drosophila	21
Selective resilience in brain aging: challenging the scope of the disposable soma theory	20
Oxygen transport across the lifespan of male Sprague Dawley rats	20
Emerging cellular senescence-centric understanding of immunological aging and its potential modulation through dietary bioactive components	20

Melatonin’s role in ameliorating perturbed circadian immune molecular links with aging and sleep deprivation in central and peripheral clocks in male Wistar rats	19
Correction: Immune genes involved in synaptic plasticity during early postnatal brain development contribute to post-stroke damage in the aging male rat brain	19
ATM and p53 in aging and cancer: a double-edged sword in genomic integrity	19
Intracellular cytokines in peritoneal leukocytes relate to lifespan in aging and long-lived female mice	19
Vascular senescence and aging: mechanisms, clinical implications, and therapeutic prospects	19
Marital and living status and biological ageing trajectories: a longitudinal cohort study with a 20-year follow-up	19
Disturbances in cell wall biogenesis as a key factor in the replicative aging of budding yeast	18
Mitochondrial function and nutrient sensing pathways in ageing: enhancing longevity through dietary interventions	18
Consumptıon of ultra-processed foods can accelerate age-related appearance of sarcopenıa	18
Elucidating the anti-aging bioactive compounds and mechanisms of Jingfang Granules formula based on network pharmacology and Caenorhabditis elegans	18
An evaluation of aging measures: from biomarkers to clocks	18
Harnessing the FOXO-SIRT1 axis: insights into cellular stress, metabolism, and aging	16
Oxidative stress-induced gene expression changes in prostate epithelial cells in vitro reveal a robust signature of normal prostatic senescence and aging	16
Berberis vulgaris L. extract supplementation exerts regulatory effects on the lifespan and healthspan of Drosophila through its antioxidant activity depending on the sex	16
The influence of sex-specific factors on biological transformations and health outcomes in aging processes	16
Aging, ROS, and cellular senescence: a trilogy in the progression of liver fibrosis	16
Aging adipose tissue, insulin resistance, and type 2 diabetes	15
From telomeres and senescence to integrated longevity medicine: redefining the path to extended healthspan	15
Zbp1 gene: a modulator of multiple aging hallmarks as potential therapeutic target for age-related diseases	15
Day time-restricted feeding shows differential synchronizing effects on age-related changes of serotonin metabolism in SCN and the pineal gland in male Wistar rats	15
Quercetin preserves mitochondria-endoplasmic reticulum contact sites improving mitochondrial dynamics in aged myocardial cells	15
Dental pulp and apical papilla cells senescence: causes, consequences, and prevention	14
G protein-coupled receptors that influence lifespan of human and animal models	14
Lipid metabolism and ageing in Caenorhabditis elegans: a complex interplay	14
Aging-related changes in metabolic indicators in female rats and their management with Tinospora cordifolia	14
The pro-aging and rejuvenating effects of young and aged perivascular adipose tissues on endothelial function and inflammation	14
Correction: Directionality theory and mortality patterns across the primate lineage	13
Alternate day fasting and time-restricted feeding may confer similar neuroprotective effects during aging in male rats	13
The role of different physical exercises as an anti-aging factor in different stem cells	13
Histone lysine methyltransferases and their specific methylation marks show significant changes in mouse testes from young to older ages	13
Beneficial death: A substantial element of evolution?	13
The nexus between peroxisome abundance and chronological ageing in Saccharomyces cerevisiae	13
Sex differences in middle-aged and old Wistar rats in response to long-term sulforaphane treatment for prevention of neuroinflammation, cognitive decline and brain senescence	12
Deciphering the molecular clock: exploring molecular mechanisms and genetic influences on skin ageing	12
Dauer larva-derived extracellular vesicles extend the life of Caenorhabditis elegans	12
Age-related differences in response to plasma exchange in male rat liver tissues: insights from histopathological and machine-learning assisted spectrochemical analyses	11
Chrysin alleviates the impeded neurogenesis in accelerated brain aging by D-galactose in rats	11
The age-dependent impacts of treadmill exercise on cognitive impairments by reducing inflammation and oxidative stress in the hippocampus of morphine-exposed rats: the role of SIRTs 3 &4 and BDNF	11
Decoding the impact of ageing and environment stressors on skin cell communication	11
The interplay between circadian rhythms and aging: molecular mechanisms and therapeutic strategies	10
Green tea EGCG effectively alleviates experimental colitis in middle-aged male mice by attenuating multiple aspects of oxi-inflammatory stress and cell cycle deregulation	10
Association of serum metabolites with frailty phenotype and its components: a cross-sectional case–control study	10
Epitalon increases telomere length in human cell lines through telomerase upregulation or ALT activity	10
Calorie-restriction treatment mitigates the aging in rat liver model	10
Aberrant telomeric structures and serum markers of telomere dysfunction in healthy aging: a preliminary study	10
Biological properties, synthetic pathways and anti-aging mechanisms of nicotinamide mononucleotide (NMN): Research progress and challenges	10
Harnessing the fundamental roles of vitamins: the potent anti-oxidants in longevity	9
Cell-type specific and differential expression of LINC-RSAS long noncoding RNA declines in the testes during ageing of the rat	9
Targeting senescence and GATA4 in age-related cardiovascular disease: a comprehensive approach	9
Directionality theory and mortality patterns across the primate lineage	9

The potential link between the development of Alzheimer’s disease and osteoporosis	9
Inhibitory immune checkpoints suppress the surveillance of senescent cells promoting their accumulation with aging and in age-related diseases	9
Mitochondria and telomeres: hand in glove	9
Lifestyle, environment and other major determinants of frailty in older adults: a population-based study from the UK Biobank	9
Mapping sex differences in the effects of protein and carbohydrates on lifespan and reproduction in Drosophila melanogaster: is measuring nutrient intake essential?	9
Identification of resibufogenin, a component of toad venom, as a novel senolytic compound in vitro and for potential skin rejuvenation in male mice	8
Correction: Quercetin and dasatinib, two powerful senolytics in age-related cardiovascular disease	8
High stability of blood parameters during mouse lifespan: sex-specific effects of every-other-day fasting	8
Distinguishing the intrinsic and extrinsic causes of changes in human mortality by examining life-table aging rate (LAR) trajectories through the lens of generalized Gompertz-Makeham law	8
The age-dependent neuroglial interaction with peripheral immune cells in coronavirus-induced neuroinflammation with a special emphasis on COVID-19	8
AMPK signaling inhibits the differentiation of myofibroblasts: impact on age-related tissue fibrosis and degeneration	8
T-cell lymphocytes’ aging clock: telomeres, telomerase and aging	8
The combination of hawthorn extract administration and high-intensity interval training (HIIT) alleviates hippocampus damage in aged rats: the behavioral, molecular and histological evaluations	8
Chrysin mitigates neuronal apoptosis and impaired hippocampal neurogenesis in male rats subjected to D-galactose-induced brain aging	8
Regulation of ENPP5, a senescence-associated secretory phenotype factor, prevents skin aging	7
Investigating genetic links between biological aging and adverse pregnancy outcomes	7
Isotschimgine promotes lifespan, healthspan and neuroprotection of Caenorhabditis elegans via the activation of nuclear hormone receptors	7
Telomeres and telomerase: active but complex players in life-history decisions	7
Therapeutic extracellular vesicles as a cornerstone of medicine in the next decade with gerontological focus	7
Enhancing the human health and lifespan: a targeted strategy emphasizing statins	7
Therapeutic potential of melatonin and its derivatives in aging and neurodegenerative diseases	7
Nicotinamide mononucleotide suppresses cellular senescence and increases aquaporin 5 expression in the submandibular gland of aged male mice to ameliorate aging-related dry mouth	7
The potential of flavonoids to mitigate cellular senescence in cardiovascular disease	7
Sustained exposure to high glucose induces differential expression of cellular senescence markers in murine macrophages but impairs immunosurveillance response to senescent cells secretome	7
Cholesterol’s hidden impact: the nonlinear link between remnant cholesterol (RC) and phenotypic age acceleration (PhenoAgeAccel)	7
Effects of aging and resistance exercise on muscle strength, physiological properties, longevity proteins, and telomere length in SAMP8 mice	7
Alterations in bone metabolites with age in C57BL/6 mice model	7
COVID-19 detection in CT and CXR images using deep learning models	7
Variety of sleep and circadian rhythms of elderly dementia patients living in group home residences	6
Analyzing different aging theories in the context of the brain: DNA damage, inflammation, redox imbalance, and neurodevelopment intertwine	6
Use of a novel technique to assess impact of age-related denervation on mouse soleus muscle function	6
Mitotherapy restores hippocampal mitochondrial function and cognitive impairment in aged male rats subjected to chronic mild stress	6
Geroscience: just another name or is there more to it?	6
Neuroimmunology in ageing and longevity: a special collection issue of Biogerontology	6
Contribution of senescent and reactive astrocytes on central nervous system inflammaging	6
High-quality dietary protein (essential amino acids matched to reproductive needs) partially breaks the lifespan and reproduction trade-off in lubber grasshoppers	6
Regulation of endothelial cell senescence via the miR-217/FOXO3 axis	6
Restricting the level of the proteins essential for the regulation of the initiation step of replication extends the chronological lifespan and reproductive potential in budding yeast	6
Tissue stretching is a confounding factor for the evaluation of neurodegeneration in the fast-ageing killifish	6
Seven knowledge gaps in modern biogerontology	6
CHIP and aging: a key regulator of proteostasis and cellular senescence	6
Dynamics of redox signaling in aging via autophagy, inflammation, and senescence	6
Chronic trans fatty acid consumption shortens lifespan in male Drosophila melanogaster on a high-sugar and high-fat diet	5
Identifying a gene signature for age-related hearing loss through machine learning and revealing the effect of the CTSS on the mice cochlea	5
Low-molecular-weight heparin ameliorates intestinal barrier dysfunction in aged male rats via protection of tight junction proteins	5
Light phase feeding and estradiol reverse ovariectomy-induced alterations in metabolism and liver clock gene expression in rat	5
Exploring TGF-β signaling in benign prostatic hyperplasia: from cellular senescence to fibrosis and therapeutic implications	5
The long noncoding RNA (LINC-RBE) expression in testicular cells is associated with aging of the rat	5
POLR3A mutations cause nucleolus abnormalities and aberrant telomerase RNA metabolism in induced pluripotent stem cells from Wiedemann-Rautenstrauch premature aging syndrome patient	5
Mitochondria: fundamental characteristics, challenges, and impact on aging	5
Daily ingestion of Akkermansia mucciniphila for one month promotes healthy aging and increases lifespan in old female mice	5
The potential use of nanozyme in aging and age‐related diseases	5
In vivo anti-aging effects of naringin, a bioflavonoid: insights from the budding yeast Saccharomyces cerevisiae as a model organism	5
Bibliometric insights into the cell cycle, aging, and metabolism: from molecular mechanisms to clinical implications	5
Plasma proteins as potential biomarkers of aging of single tissue and cell type	5
Photoaging: UV radiation-induced cGAS-STING signaling promotes the aging process in skin by remodeling the immune network	5
Exploring new markers for biological aging from bioimpedance analysis and cognitive functions in older adults	5
12-ethoxy-Marchantin A, a new macrocyclic bis-bibenzyl from Marchantia polymorpha L., exerts anti-aging activity through activating MAPKs-dependent Nrf2/HO-1 signaling pathways	5
Hyperoside extends lifespan in Caenorhabditis elegans through SEK-1/PMK-1/SKN-1 pathway	5
Redox modulatory role of DJ-1 in Parkinson’s disease	5
The expression of fibrosis-related genes is elevated in doxorubicin-induced senescent human dermal fibroblasts, but their secretome does not trigger a paracrine fibrotic response in non-senescent cell	5
Changing dynamics in daily rhythms of oxidative stress indicators in SCN and extra-SCN brain regions with aging in male Wistar rats	5
Heat-induced hormesis in longevity is linked to heat-stress sensitivity across laboratory populations from diverse altitude of origin in Drosophila buzzatii	5
Aging influences protein digestion, absorption and amino acid metabolism	4
The potential longevity-promoting hypoxic-hypercapnic environment as a measure for radioprotection	4
Caloric restriction mimetics improve gut microbiota: a promising neurotherapeutics approach for managing age-related neurodegenerative disorders	4
The SGLT2 inhibitor empagliflozin inhibits skeletal muscle fibrosis in naturally aging male mice through the AMPKα/MMP9/TGF-β1/Smad pathway	4
The impact of physical exercise on genotoxicity in older adults: a systematic review	4
Blood-based biomarkers in centenarians and non-centenarians: a matched, population-based retrospective cohort study using primary care records in Catalonia, Spain	4
Telomeres in health and longevity: special issue in memory of Alexey Olovnikov	4
The protein cargo of extracellular vesicles correlates with the epigenetic aging clock of exercise sensitive DNAmFitAge	4
The role of genetic/epigenetic factors and microenvironment in hematopoietic stem cell ageing	4
The aging male: impact of aging on male reproduction	4
Multifaceted dynamics of circadian timing system influence aging and longevity	4
Metabolic and physical function are improved with lifelong 15% calorie restriction in aging male mice	4
Beta-Hydroxybutyrate but not NMN supplementation mimics caloric restriction reducing early mortality in Daphnia	4
Precision nutrition in epigenetic aging: SHAP-optimized machine learning identifies omega-3 constituent-specific associations with aging biomarkers	4
Quercetin and dasatinib, two powerful senolytics in age-related cardiovascular disease	4
Application potential of senolytics in clinical treatment	4
Obstructive sleep apnea and aging of the cardiovascular system: a multidimensional analysis of the mechanisms involved	4

Ribose-induced advanced glycation end products reduce the lifespan in Drosophila melanogaster by changing the redox state and down-regulating the Sirtuin genes	4
Age-related decline in the expression of BRG1, ATM and ATR are partially reversed by dietary restriction in the livers of female mice	4
Coniferaldehyde activates autophagy and enhances oxidative stress resistance and lifespan of Caenorhabditis elegans via par-4/aak-2/skn-1 pathway	4
Differential effects of aging on hippocampal ultrastructure in male vs. female rats	4
The mitochondrial and cytoplasmic superoxide anion imbalance trigger the expression of certain cellular aging markers in HaCaT keratinocytes	4
Analyzing the causal role of blood cells in aging: a Mendelian randomization study	3
The dichotomic role of cytokines in aging	3
Environmental enrichment: a neurostimulatory approach to aging and ischemic stroke recovery and rehabilitation	3
How soon do metabolic alterations and oxidative distress precede the reduction of muscle mass and strength in Wistar rats in aging process?	3
Adult-restricted gene knock-down reveals candidates that affect locomotive healthspan in C. elegans	3
Role of circadian CLOCK signaling in cellular senescence	3
Delayed cutaneous wound healing in young and old female mice is associated with differential growth factor release but not inflammatory cytokine secretion	3
Measuring healthy ageing: current and future tools	3
Estrogen receptor alpha mediates 17β-estradiol, up-regulates autophagy and alleviates hydrogen peroxide-induced vascular senescence	3
Invariances in relations between aging, exposure to external hazards, and mortality reflected in life table aging rate (LAR) patterns examined through the lens of generalized Gompertz–Makeham law	3
Sex-dependent geroprotective effects of malvidin in Drosophila melanogaster	3
Circulating immune cells in cerebral small vessel disease: a systematic review	3
Telomeres and aging: on and off the planet!	3
Overexpression of the Dicer family genes influences lifespan and stress resistance in a tissue-, sex-, and stressor-specific manner in Drosophila melanogaster	3
Enhancing healthspan with Ashwagandha (Withania somnifera): a comprehensive review of its multifaceted geroprotective benefits	3
“Slight chemical damage due to drinking modest amount of sake, might induce beneficial effects” as a form of hormesis: an interview with Professor Sataro Goto	3
Immunoinformatic-based drug design utilizing hesperetin to target CISD2 activation for liver aging in humans	3
Chromosome ends and the theory of marginotomy: implications for reproduction	3
The effects of estrogen depletion in female rats: differential influences on somato-motor and sensory cortices	2
Long-term sulforaphane-treatment restores redox homeostasis and prevents cognitive decline in middleaged female and male rats, but cannot revert previous damage in old animals	2
A comprehensive model for the biochemistry of ageing, senescence and longevity	2
A novel rat model of sarcopenic obesity based on aging and high-fat diet consumption	2
Cortisol, DHEAS, and the cortisol/DHEAS ratio as predictors of epigenetic age acceleration	2
Lack of age-related respiratory changes in Daphnia	2
Linking telomere dynamics to evolution, life history and environmental change: perspectives, predictions and problems	2
The role of Smo-Shh/Gli signaling activation in the prevention of neurological and ageing disorders	2
Inflammaging in domestic dogs: basal level concentrations of IL-6, IL-1β, and TNF-α in serum of healthy dogs of different body sizes and ages	2
Alterations in hippocampal mitochondrial dynamics are associated with neurodegeneration and recognition memory decline in old male mice	2
Lipofuscin, amyloids, and lipid peroxidation as potential markers of aging in Daphnia	2
FOXO3a upregulates DNA repair activities by transcriptional activation of target genes and provides the resistance to gamma radiation and the extension of lifespan in mouse	2
Dietary interventions and molecular mechanisms for healthy musculoskeletal aging	2
An AMP Kinase-pathway dependent integrated stress response regulates ageing and longevity	2
Correction to: Estrogen receptor alpha mediates 17β-estradiol, up-regulates autophagy and alleviates hydrogen peroxide-induced vascular senescence	2
Early and long-term effects of maternal protein restriction on offspring organs and systems: insights from the developmental origins of health and disease (DOHaD)	2
Hormesis is an evolutionary expectation: implications for aging	2
Essential amino acids and branched-chain amino acids are associated with skeletal muscle and inflammatory parameters in older age	2
Translational potential of GADD45α: biomarker and therapeutic target in age-associated neurodegeneration and longevity	2
The role of phagocytic cells in aging: insights from vertebrate and invertebrate models	2
Correction: Empaglifozin improves kidney senescence induced by d-galactose by reducing sirt1-mediated oxidative stress	2
Melatonin-related signaling pathways and their regulatory effects in aging organisms	2
Aging and short-term calorie restriction differently affect the cardiac and skeletal muscle expression of genes regulating energy substrate utilization in male rats	2
Aging-accelerated differential production and aggregation of STAT3 protein in neuronal cells and neural stem cells in the male mouse spinal cord	2
Hypertension and cellular senescence	2
The effects of different types of calorie restrictions on epigenetic modifications of age-related genes in aging mouse brain	2
CeO2 nanoparticles improve prooxidant/antioxidant balance, life quality and survival of old male rats	2
Maternal malnutrition induces inflammatory pathways and oxidative stress in the dorsolateral prostate of male offspring rats	2
Effects of low-intensity pulsed ultrasound on muscle mass and Fndc5 mRNA expression in aged male mice	2
Genetically predicted causal links between gut microbiota and biological aging phenotypes in age-related macular degeneration	2
GDF15/MIC-1: a stress-induced immunosuppressive factor which promotes the aging process	2
Whole-body vibration elicits 40 Hz cortical gamma oscillations and ameliorates age-related cognitive impairment through hippocampal astrocyte synapses in male rats	2
2,4-Dinitrophenol is toxic on a low caloric diet but extends lifespan of Drosophila melanogaster on nutrient-rich diets without an impact on metabolism	2
Associations between dietary carotenoid and biological age acceleration: insights from NHANES 2009–2018	2
Alexey Olovnikov: theoretical biology beyond the margins	2
Telomeres in skin aging	2
Biochemical, structural and physical changes in aging human skin, and their relationship	2
Hormetic association between perceived stress and human epigenetic aging based on resilience capacity	2