International Journal of Molecular Sciences

Article	Citations
Inhibition of Casein Kinase 1δ as a Novel Therapeutic Strategy for Amyotrophic Lateral Sclerosis: A Theoretical Study	904
Optimizing Positive End-Expiratory Pressure in Asymmetric Acute Lung Injury in a Porcine Model: The Role of Transpulmonary Pressure	757
Coronavirus Disease 2019-Associated Thrombotic Microangiopathy: A Single-Center Experience	623
Role of the Inflammasome Pathway According to the Expression of Proteins and Genetic Polymorphisms in COVID-19 Patients	571
Nanostructured Coatings Based on Graphene Oxide for the Management of Periprosthetic Infections	570
Sex-Biased Expression and Response of microRNAs in Neurological Diseases and Neurotrauma	553
Time-Resolved Proteomics of Germinating Spores of Bacillus cereus	553
Effects of CSN1/CSN2 Mutants in Flavonoid Metabolism on Rice (Oryza sativa L.)	495
Transcriptomic Alterations in Spliceosome Components in Advanced Heart Failure: Status of Cardiac-Specific Alternative Splicing Factors	477
Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells	476
Impact of Copper Nanoparticles on Keratin 19 (KRT19) Gene Expression in Breast Cancer Subtypes: Integrating Experimental and Bioinformatics Approaches	412
Functional Identification of HhUGT74AG11—A Key Glycosyltransferase Involved in Biosynthesis of Oleanane-Type Saponins in Hedera helix	402
Gestational Diabetes Exposed Mesenchymal Stem Cells: Phenotypic Differences Link to Long-Term Health of Offspring	384
MicroRNA: A Dynamic Player from Signalling to Abiotic Tolerance in Plants	380
Towards Arginase Inhibition: Hybrid SAR Protocol for Property Mapping of Chlorinated N-arylcinnamamides	379
Combination of 20(R)-Rg3 and HUCMSCs Alleviates Type 2 Diabetes Mellitus in C57BL/6 Mice by Activating the PI3K/Akt Signaling Pathway	379
Associations of Glucometabolic Indices with Aortic Stiffness in Patients Undergoing Peritoneal Dialysis with and without Diabetes Mellitus	363
Traditional Health Practices May Promote Nrf2 Activation Similar to Exercise	357
An Efficient 5-Aminolevulinic Acid Photodynamic Therapy Treatment for Human Hepatocellular Carcinoma	351
Polymeric Interlayer in CdS-Free Electron-Selective Contact for Sb2Se3 Thin-Film Solar Cells	351
Modulation of α-Mannosidase 8 by Antarctic Endophytic Fungi in Strawberry Plants Under Heat Waves and Water Deficit Stress	349
The Primary Microglial Leukodystrophies: A Review	342
Heat Shock Protein 70 Is Involved in the Efficiency of Preconditioning with Cyclosporine A in Renal Ischemia Reperfusion Injury by Modulating Mitochondrial Functions	341
Antiproliferative Role of Natural and Semi-Synthetic Tocopherols on Colorectal Cancer Cells Overexpressing the Estrogen Receptor β	340
Stimulation of Peripheral Blood Mononuclear Cells with Lactococcus lactis Strain Plasma Elicits Antiviral Effects Against H1N1 and SARS-CoV-2	334

Dietary Gluten-Free Regimen Does Not Affect the Suppression of the Inflammatory Response in the Arachidonic Acid Cascade in Hashimoto’s Disease	329
Capacitance-Driven Modulation of Cardiac Impulse Conduction by an Intramembrane Molecular Photoswitch	325
GUS Reporter-Aided Promoter Deletion Analysis of A. thaliana POLYAMINE OXIDASE 3	325
The Presence of Plasmids in Lactococcus lactis IL594 Determines Changes in the Host Phenotype and Expression of Chromosomal Genes	321
Two-Component System Genes in Brassica napus: Identification, Analysis, and Expression Patterns in Response to Abiotic and Biotic Stresses	321
Lacticaseibacillus rhamnosus MS27 Potentially Prevents Ulcerative Colitis Through Modulation of Gut Microbiota	321
Genome-Wide Identification and Functional Characterization of the Dof Family in Dendrobium officinale	317
Generation of Matrix Degradation Products Using an In Vitro MMP Cleavage Assay	315
The Protective Role of Interleukin-37 in Cardiovascular Diseases through Ferroptosis Modulation	314
Proteomic Profiling of an Exosome-Enriched Extracellular Vesicle Fraction and Structural Characterization of SMPDL3A in the Carcinogenic Liver Fluke Clonorchis sinensis	312
Molecular Analysis of PIK3CA in Metastatic Hormone Receptor-Positive Breast Cancer in Chile: Clinical and Pathological Insights	311
Lycopene Inhibits PRRSV Replication by Suppressing ROS Production	309
Development of a Polymeric Film Entrapping Rose Bengal and Iodide Anion for the Light-Induced Generation and Release of Bactericidal Hydrogen Peroxide	306
Integral Algorithms to Evaluate TiO2 and N-TiO2 Thin Films’ Cytocompatibility	304
High-Pressure Processing Influences Antibiotic Resistance Gene Transfer in Listeria monocytogenes Isolated from Food and Processing Environments	304
Revitalizing Colchicine: Novel Delivery Platforms and Derivatives to Expand Its Therapeutic Potential	303
Influence of Cupric (Cu2+) Ions on the Iron Oxidation Mechanism by DNA-Binding Protein from Starved Cells (Dps) from Marinobacter nauticus	300
Exploration of Multiverse Activities of Endocannabinoids in Biological Systems	298
Transcriptomic Analysis Reveals the Potential Mechanism of Cardamine circaeoides Hook.f. & Thomson in Lowering Serum Uric Acid by Reducing Inflammatory State Through CCR7 Target	297
Epididymal-Born circRNA Cargo and Its Implications in Male Fertility	293
The Complex Proteolipidic Behavior of the SARS-CoV-2 Envelope Protein Channel: Weak Selectivity and Heterogeneous Oligomerization	292
Current Trends of Bacterial and Fungal Optoproteins for Novel Optical Applications	291
OsHsfB4b Confers Enhanced Drought Tolerance in Transgenic Arabidopsis and Rice	291
Expression Profiling of Coding and Noncoding RNAs in the Endometrium of Patients with Endometriosis	288
Increased Lipogenesis Is Important for Hexavalent Chromium-Transformed Lung Cells and Xenograft Tumor Growth	287
Polyacrylic-Coated Solid Nanoparticles Increase the Aquaporin Permeability to Hydrogen Peroxide	287
Chemoradiation-Altered Micromilieu of Glioblastoma Cells Particularly Impacts M1-like Macrophage Activation	286
Pro-Apoptotic Effects of Unsymmetrical Bisacridines in 3D Pancreatic Multicellular Tumor Spheroids	280
Advanced SnO2 Thin Films: Stability and Sensitivity in CO Detection	278
The Combination of Gold and Silver Food Nanoparticles with Gluten Peptides Alters the Autophagic Pathway in Intestinal Crypt-like Cells	275
Exploring Daptomycin Hypersensitivity in Enterococcus faecium: The Impact of LafB Mutation on Bacterial Virulence	273
From Skeletal Muscle to Myocardium: Molecular Mechanisms of Exercise-Induced Irisin Regulation of Cardiac Fibrosis	268
Strigolactones Might Regulate Ovule Development after Fertilization in Xanthoceras sorbifolium	265
Functionalised Mesoporous Silica Thin Films as ROS-Generating Antimicrobial Coatings	265
Identification and Characterization of 5-HT Receptor 1 from Scylla paramamosain: The Essential Roles of 5-HT and Its Receptor Gene during Aggressive Behavior in Crab Species	262
Mining of Minor Disease Resistance Genes in V. vinifera Grapes Based on Transcriptome	259
Nebulized Lipopolysaccharide Causes Delayed Cortical Neuroinflammation in a Murine Model of Acute Lung Injury	258
Molecular Mechanism and Application of Somatic Cell Cloning in Mammals—Past, Present and Future	258
Efficient Production of Recombinant Human Brain-Derived Neurotrophic Factor in Escherichia coli Through the Engineering of Its Pro-Region	257
Genome-Wide Characterization and Function Analysis of ZmERD15 Genes’ Response to Saline Stress in Zea mays L.	256
Molecular Detection and Genotyping of Enterocytozoon bieneusi in Environmental Sources near Cattle Farms in Korea	255
Ceramide AD™ Restores Skin Integrity and Function following Exposure to House Dust Mite	254
The Role of the Glucocorticoid Receptor and Its Phosphorylation in Neurological Disorders	253
A Novel Class I HDAC Inhibitor, AW01178, Inhibits Epithelial–Mesenchymal Transition and Metastasis of Breast Cancer	252
No Evidence of Gut Microbiota Alteration in Psoriasis Patients Switching to Brodalumab after Loss of TNFα Inhibition Effect	250
Narirutin-Rich Celluclast Extract from Mandarin (Citrus unshiu) Peel Alleviates High-Fat Diet-Induced Obesity and Promotes Energy Metabolism in C57BL/6 Mice	248
Single-Nucleotide Polymorphism in Genes Encoding G Protein Subunits GNB3 and GNAQ Increase the Risk of Cardiovascular Morbidity among Patients Undergoing Renal Replacement Therapy	245
G Protein-Coupled Receptors in Cerebrovascular Diseases: Signaling Mechanisms and Therapeutic Opportunities	240
Cerebral Benefits Induced by Electrical Muscle Stimulation: Evidence from a Human and Rat Study	240
Genetic and Clinical Determinants of Chronic Thromboembolic Pulmonary Hypertension: The Role of PAI-1 Polymorphism	239

Potent Alkaline Phosphatase Inhibitors, Pyrazolo-Oxothiazolidines: Synthesis, Biological Evaluation, Molecular Docking, and Kinetic Studies	237
Aging-Related Gene-Based Prognostic Model for Lung Adenocarcinoma: Insights into Tumor Microenvironment and Therapeutic Implications	235
Fluoroplast Doped by Ag2O Nanoparticles as New Repairing Non-Cytotoxic Antibacterial Coating for Meat Industry	233
The Interplay Between the MYC Oncogene and Ribosomal Proteins in Osteosarcoma Onset and Progression: Potential Mechanisms and Indication of Candidate Therapeutic Targets	233
Examining the Roles of Genomic Context and Endogenous Regulatory Elements on IS1 Transposition Within the Escherichia coli Genome	228
Cumulative Deleterious Effects of Tetrahydrocannabinoid (THC) and Ethanol on Mitochondrial Respiration and Reactive Oxygen Species Production Are Enhanced in Old Isolated Cardiac Mitochondria	225
Polyphenon E Effects on Gene Expression in PC-3 Prostate Cancer Cells	223
Molecular Characterization and Mutational Analysis of Clarithromycin- and Levofloxacin-Resistance Genes in Helicobacter pylori from Gastric Biopsies in Southern Croatia	221
Enhancer Regulation of Dopaminergic Neurochemical Transmission in the Striatum	221
Molecular and Genetics Perspectives on Primary Adrenocortical Hyperfunction Disorders	220
The Protective Effect of Quercetin against the Cytotoxicity Induced by Fumonisin B1 in Sertoli Cells	220
Influence of Anticoagulants on the Dissociation of Cardiac Troponin Complex in Blood Samples	219
Blood Neurofilament Light Chain and Glial Fibrillary Acidic Protein as Promising Screening Biomarkers for Brain Metastases in Patients with Lung Cancer	219
Artificial Intelligence-Driven Integration of ECG and Molecular Biomarkers in Pulmonary Embolism	218
Sustainable Plant-Based Biopolymer Membranes for PEM Fuel Cells	216
MP Allosterically Activates AMPK to Enhance ABCA1 Stability by Retarding the Calpain-Mediated Degradation Pathway	212
Rli51 Attenuates Transcription of the Listeria Pathogenicity Island 1 Gene mpl and Functions as a Trans-Acting sRNA in Intracellular Bacteria	212
Antiseptic, Hemostatic, and Wound Activity of Poly(vinylpyrrolidone)-Iodine Gel with Trimethyl Chitosan	212
Macrophages: Key Players in the Battle against Triple-Negative Breast Cancer	208
Expression of DNA Methyltransferase 3B Isoforms Is Associated with DNA Satellite 2 Hypomethylation and Clinical Prognosis in Advanced High-Grade Serous Ovarian Carcinoma	207
Mesoscale Simulations of Structure Formation in Polyacrylonitrile Nascent Fibers Induced by Binary Solvent Mixture	207
Novel Nickel(II), Palladium(II), and Platinum(II) Complexes with O,S Bidendate Cinnamic Acid Ester Derivatives: An In Vitro Cytotoxic Comparison to Ruthenium(II) and Osmium(II) Analogues	206
Mechanism of Functional Compound Fruit Drinks in Regulating Serum Metabolism in Constipated Mice	205
Classification of Subgroups with Immune Characteristics Based on DNA Methylation in Luminal Breast Cancer	204
Dimerisation of the Yeast K+ Translocation Protein Trk1 Depends on the K+ Concentration	202
Macromolecular Structure of Linearly Arranged Eukaryotic Chromosomes	201
5-Aminolevrinic Acid Exhibits Dual Effects on Stemness in Human Sarcoma Cell Lines under Dark Conditions	201
Function of Cajal Bodies in Nuclear RNA Retention in A. thaliana Leaves Subjected to Hypoxia	200
Cost-Effective Mechanical Aggregation of Cardiac Progenitors and Encapsulation in Matrigel Support Self-Organization in a Dynamic Culture Environment	198
Strategies for Altering Delivery Technologies to Optimize CAR Therapy	198
Multi-Modal and Molecular Imaging of Cellular Microenvironment and Tissue Development	198
Molecular Diagnostic and Prognostication Assays for the Subtyping of Urinary Bladder Cancer Are on the Way to Illuminating Our Vision	197
Loss of Myostatin Affects m6A Modification but Not Semen Characteristics in Bull Spermatozoa	196
Improving Replication in Endometrial Omics: Understanding the Influence of the Menstrual Cycle	196
Cytokine Dynamics in Autism: Analysis of BMAC Therapy Outcomes	194
Mitochondrial Genome Characteristics Reveal Evolution of Danxiaorchis yangii and Phylogenetic Relationships	194
Novel Conformation-Dependent Tau Antibodies Are Modulated by Adjacent Phosphorylation Sites	194
VX-770, Cact-A1, and Increased Intracellular cAMP Have Distinct Acute Impacts upon CFTR Activity	194
Novel Assignment of Gene Markers to Hematological and Immune Cells Based on Single-Cell Transcriptomics	194
Alterations in Intratumoral Immune Response before and during Early-On Nivolumab Treatment for Unresectable Advanced or Recurrent Gastric Cancer	193
Starting Editorial of “Cellular Damage: Protection and Induction” Addressing Hot Topics in Cellular Damage, Protection of Cells and Therapy Targeting Bad Cells	193
Glucokinase Variant Proteins Are Resistant to Fasting-Induced Uridine Diphosphate Glucose-Dependent Degradation in Maturity-Onset Diabetes of the Young Type 2 Patients	193
Singularity and Commonality in Response to SARS-CoV-2 in Lung and Colon Cell Models	191
3′dNTP Binding Is Modulated during Primer Synthesis and Translesion by Human PrimPol	189
PET Molecular Imaging: Old Habits Do Not Die, They Only Evolve into New Applications	188
Physiological, Proteomic, and Resin Yield-Related Genes Expression Analysis Provides Insights into the Mechanisms Regulating Resin Yield in Masson Pine	186
Dynamic Properties of Di(cyclopentadienecarboxylic Acid) Dimethyl Esters	185
Genome-Wide Identification and Comprehensive Analysis of the GASA Gene Family in Peanuts (Arachis hypogaea L.) under Abiotic Stress	184
Comparative RNA-Seq Analysis Revealed Tissue-Specific Splicing Variations during the Generation of the PDX Model	183
Petiveria alliacea Reduces Tumor Burden and Metastasis and Regulates the Peripheral Immune Response in a Murine Myeloid Leukemia Model	181
Immunohistochemical Expression Analysis of Caldesmon Isoforms in Colorectal Carcinoma Reveals Interesting Correlations with Tumor Characteristics	180
The Co-Expression Pattern of Calcium-Binding Proteins with γ-Aminobutyric Acid and Glutamate Transporters in the Amygdala of the Guinea Pig: Evidence for Glutamatergic Subpopulations	180
Investigating Antibody Reactivity to the Intestinal Microbiome in Severe Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Feasibility Study	180
My Name Is Legion, for We Are Many—The Complex Community of Antibody Receptors	180
Revealing the Role of Alternariol in the Local Steroidogenesis in Human Prostate Normal and Cancer Cells	179
Investigating the Modulation of the VTA Neurons in Nicotine-Exposed Pups during Early Maturation Using Optogenetics	179
Friend or Foe? Locoregional Therapies and Immunotherapies in the Current Hepatocellular Treatment Landscape	177
Mixed-Lineage Leukemia 1 Inhibition Enhances the Differentiation Potential of Bovine Embryonic Stem Cells by Increasing H3K4 Mono-Methylation at Active Promoters	176
Nitric Oxide Prevents Glioblastoma Stem Cells’ Expansion and Induces Temozolomide Sensitization	176
A Transcriptome-Wide Analysis of Psoriasis: Identifying the Potential Causal Genes and Drug Candidates	175
Repressive Control of Keratinocyte Cytoplasmic Inflammatory Signaling	174
Long Dynamic β1–β2 Loops in M. tb MazF Toxins Affect the Interaction Modes and Strengths of the Toxin–Antitoxin Pairs	174
Relationship between GABA-Ergic System and the Expression of Mephedrone-Induced Reward in Rats—Behavioral, Chromatographic and In Vivo Imaging Study	173
Knockout of the Carbohydrate Responsive Element Binding Protein Enhances Proliferation and Tumorigenesis in Renal Tubules of Mice	173
Follicular Lymphoma Microenvironment Traits Associated with Event-Free Survival	172
Novel SPEA Superantigen Peptide Agonists and Peptide Agonist-TGFαL3 Conjugate. In Vitro Study of Their Growth-Inhibitory Effects for Targeted Cancer Immunotherapy	171
Molecular Mechanism in the Development of Pulmonary Fibrosis in Patients with Sarcoidosis	171
Versatile and Accessible Magnetic Diagnosis Platform with Different Types of Magnetic Particles for Liquid and Solid Biopsies	171
N-N(+) Bond-Forming Intramolecular Cyclization of O-Tosyloxy β-Aminopropioamidoximes and Ion Exchange Reaction for the Synthesis of 2-Aminospiropyrazolilammonium Chlorides and Hexafluorophosphates	169
Lung Surfactant Protein B Peptide Mimics Interact with the Human ACE2 Receptor	169
Effects of Different Types of Recombinant SARS-CoV-2 Spike Protein on Circulating Monocytes’ Structure	168
Pevonedistat Inhibits SOX2 Expression and Sphere Formation but Also Drives the Induction of Terminal Differentiation Markers and Apoptosis within Arsenite-Transformed Urothelial Cells	168
State of the Art and New Trends from the 2022 Gism Annual Meeting	168
RNA Regulatory Networks 2.0	168
IDO1 Protein Is Expressed in Diagnostic Biopsies from Both Follicular and Transformed Follicular Patients	167
Ion and Molecule Transport in Membrane Systems 3.0 and 4.0	167
Gamma-Hemolysin Components: Computational Strategies for LukF-Hlg2 Dimer Reconstruction on a Model Membrane	167
An Improved RNA Extraction Protocol for Rye Grain Full-Length Transcriptome Sequencing	167
BioGraph: Data Model for Linking and Querying Diverse Biological Metadata	167
Preliminary Preclinical Evaluation of Innovative Bone Scaffolds Composed of Natural Sources–Whey Protein Isolate and Pearl Powder	166

Identification of Drug Repurposing Candidates for Coxsackievirus B3 Infection in iPSC-Derived Brain-like Endothelial Cells	166
Low-Temperature Uniaxial Orientation Effect on the Structure and Piezoelectric Properties of the Vinylidene Fluoride-Tetrafluoroethylene Copolymer Films	166
Characterisation of Four New Genes in the Ovine KAP19 Family	165
The Role of Fibroblasts in Melanoma Development: From Tumor Microenvironment Remodeling to Pre-Metastatic Niche Formation	164
Metabolomic Analysis Provides Insights into Bud Paradormancy in Camellia sinensis cv. Huangdan	164
Comprehensive Anatomical Staging Predicts Clinical Progression in Mild Cognitive Impairment: A Data-Driven Approach	164
Cloning, Expression and Functional Characterization of V. vinifera CAT2 Arginine Transporter	163
Association of Tissue Expression of LAG-3 and TIM-3 with Clinical Features in Ovarian Cancer	163
The Non-Peptide MAS-R Agonist AVE0991 Alleviates Colitis Severity in Mice and Exhibits an Additive Effect with Azathioprine	163