OOIR: Observatory of International Research

Papers

(The median citation count of Biological Chemistry is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Frontmatter	43
Frontmatter	42
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking	34
Highlight: young research groups in Germany – 5th edition	32
Yme2, a putative RNA recognition motif and AAA+ domain containing protein, genetically interacts with the mitochondrial protein export machinery	31
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation	23
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression	20
Diversification of glutathione transferases in plants and their role in oxidative stress defense	20
Exceptionally versatile take II: post-translational modifications of lysine and their impact on bacterial physiology	19
Development of an enabling platform biotechnology for the production of proteins	19
Structural homology of mite profilins to plant profilins is not indicative of allergic cross-reactivity	19
Mechanism of hypoxia-induced exosome circ_0051799 regulating the progression of lung adenocarcinoma	18
Diselenide-derivative of 3-pyridinol targets redox enzymes leading to cell cycle deregulation and apoptosis in A549 cells	18
Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3 -deficient mice	17
The Mycobacterium tuberculosis prolyl dipeptidyl peptidase cleaves the N-terminal peptide of the immunoprotein CXCL-10	17
Implications of TRPM3 and TRPM8 for sensory neuron sensitisation	16
Computational resolution in single molecule localization – impact of noise level and emitter density	16
Influence of inflammatory processes on thalamocortical activity	15
Asymmetric horseshoe-like assembly of peroxisomal yeast oxalyl-CoA synthetase	14
Protein transport along the presequence pathway	14
Broadened substrate specificity of bacterial dipeptidyl-peptidase 7 enables release of half of all dipeptide combinations from peptide N-termini	14
Frontmatter	13
Frontmatter	13
Highlight: structure and function of the peroxisomal translocon	13
Highlights in biochemistry Bochum 2022	13

A tailored cytochrome P450 monooxygenase from Gordonia rubripertincta CWB2 for selective aliphatic monooxygenation	12
Pathogenic missense variants of CSNK2B associated with Poirier-Bienvenu neurodevelopmental disorder impact differently on CK2 holoenzyme formation	12
Detection of a 7SL RNA-derived small non-coding RNA using Molecular Beacons in vitro and in cells	12
Comparative studies of soluble and immobilized Fe(III) heme-peptide complexes as alternative heterogeneous biocatalysts	12
Unpaired cysteine insertions favor transmembrane dimerization and induce ligand-independent constitutive cytokine receptor signaling	11
Methionine restriction attenuates the migration and invasion of gastric cancer cells by inhibiting nuclear p65 translocation through TRIM47	11
Simultaneous spectral illumination of microplates for high-throughput optogenetics and photobiology	11
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system	11
Protein engineering & design: hitting new heights	10
Structures and nucleic acid-binding preferences of the eukaryotic ARID domain	10
The nascent polypeptide-associated complex (NAC) as regulatory hub on ribosomes	10
Structure and phase separation of the C-terminal domain of RNA polymerase II	10
Apolipoprotein E-containing lipoproteins and their extracellular interactions with LRP1 affect LPS-induced inflammation	10
Protein kinase CK2 contributes to glucose homeostasis	10
Frontmatter	10
Dynamics of the translocation pore of the human peroxisomal protein import machinery	10
The Zika virus infection remodels the expression of the synaptotagmin-9 secretory protein	10
The emerging role of ATP as a cosolute for biomolecular processes	9
Frontmatter	9
KCTD5 regulates Ikaros degradation induced by chemotherapeutic drug etoposide in hematological cells	9
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	9
In vitro ADME characterization of a very potent 3-acylamino-2-aminopropionic acid-derived GluN2C-NMDA receptor agonist and its ester prodrugs	9
Inhibition of miR-143-3p alleviates myocardial ischemia reperfusion injury via limiting mitochondria-mediated apoptosis	9
Sarcomere analysis in human cardiomyocytes by computing radial frequency spectra	9
Insights in caveolae protein structure arrangements and their local lipid environment	9
Structural basis of Alzheimer β-amyloid peptide recognition by engineered lipocalin proteins with aggregation-blocking activity	8
Unfolded protein responses in Chlamydomonas reinhardtii	8
Microtubules as a signal hub for axon growth in response to mechanical force	8
Eukaryotic tRNA splicing – one goal, two strategies, many players	8
Frontmatter	8
Conserved function, divergent evolution: mitochondrial outer membrane insertases across eukaryotes	8
Frontmatter	8
Highlight: new developments in immunoengineering	8
Frontmatter	8
A guide to designing photocontrol in proteins: methods, strategies and applications	8
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na⁺ channels	8
Pathological and physiological roles of ADP-ribosylation: established functions and new insights	7
Extracellular stimulation of lung fibroblasts with arachidonic acid increases interleukin 11 expression through p38 and ERK signaling	7
The BCL11A transcription factor stimulates the enzymatic activities of the OGG1 DNA glycosylase	7
Chemerin – exploring a versatile adipokine	7
Frontmatter	7
Membrane binding and pore forming insertion of PEX5 into horizontal lipid bilayer	7
Molecular simulations of DEAH-box helicases reveal control of domain flexibility by ligands: RNA, ATP, ADP, and G-patch proteins	7
Atomistic insight into the essential binding event of ACE2-derived peptides to the SARS-CoV-2 spike protein	7
Highlight: how to synthesize, assemble and regulate ribonucleoprotein-complexes	7
Small-molecule metabolites in SARS-CoV-2 treatment: a comprehensive review	7
Distinct conformational and energetic features define the specific recognition of (di)aromatic peptide motifs by PEX14	7
Interaction of RTX toxins with the host cell plasma membrane	7
Application of RtcB ligase to monitor self-cleaving ribozyme activity by RNA-seq	7
Rodent models for mood disorders – understanding molecular changes by investigating social behavior	6

NF90/NFAR (nuclear factors associated with dsRNA) – a new methylation substrate of the PRMT5-WD45-RioK1 complex	6
Interaction of nucleoporins with nuclear transport receptors: a structural perspective	6
MicroRNA-6838-5p suppresses the self-renewal and metastasis of human liver cancer stem cells through downregulating CBX4 expression and inactivating ERK signaling	6
CK2 control of human papillomavirus life cycles	6
Modulation of self-organizing circuits at deforming membranes by intracellular and extracellular factors	6
The second PI(3,5)P₂ binding site in the S0 helix of KCNQ1 stabilizes PIP₂-at the primary PI1 site with potential consequences on intermediate-to-open state transit	6
The promise of genetic screens in human in vitro brain models	6
Study of two glycosyltransferases related to polysaccharide biosynthesis in Rhodococcus jostii RHA1	6
The evolution and diversification of the Hsp90 co-chaperone system	6
Analysis of cell cycle stage, replicated DNA, and chromatin-associated proteins using high-throughput flow cytometry	6
Highlight: on the past and the future of cellular microcompartments	6
The 76th Mosbacher Colloquium: AI-driven (r)evolution in structural biology and protein design	6
Bovine ultralong CDR-H3 derived knob paratopes elicit potent TNF-α neutralization and enable the generation of novel adalimumab-based antibody architectures with augmented features	6
Cell-type specific anti-cancerous effects of nitro-oleic acid and its combination with gamma irradiation	6
Protein persulfidation in plants: mechanisms and functions beyond a simple stress response	6
Cathepsin L-mediated EGFR cleavage affects intracellular signalling pathways in cancer	5
Celastrol inhibits angiogenesis and the biological processes of MDA-MB-231 cells via the DEGS1/S1P signaling pathway	5
The mitochondrial intermembrane space – a permanently proteostasis-challenged compartment	5
LINC00858 facilitates formation of hepatic metastases from colorectal cancer via regulating the miR-132-3p/IGF2BP1 axis	5
Interactions of Na⁺/taurocholate cotransporting polypeptide with host cellular proteins upon hepatitis B and D virus infection: novel potential targets for antiviral therapy	5
Illuminating the brain-genetically encoded single wavelength fluorescent biosensors to unravel neurotransmitter dynamics	5
Frontmatter	5
Transfer RNA processing – from a structural and disease perspective	5
Prodrug-Activating Chain Exchange (PACE) converts targeted prodrug derivatives to functional bi- or multispecific antibodies	5
Frontmatter	5
M2 macrophages-derived exosomal miR-3917 promotes the progression of lung cancer via targeting GRK6	5
Frontmatter	5
Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2	5
Getting to the right place at the right time – membrane trafficking and maturation in the endolysosomal system	5
Investigation of the P1′ and P2′ sites of IQF substrates and their selectivity toward 20S proteasome subunits	5
The many faces of ribosome translocation along the mRNA: reading frame maintenance, ribosome frameshifting and translational bypassing	5
Inhibition of Chk1 stimulates cytotoxic action of platinum-based drugs and TRAIL combination in human prostate cancer cells	4
Frontmatter	4
Frontmatter	4
New lipophilic organic nitrates: candidates for chronic skin disease therapy	4
Structure and function of spliceosomal DEAH-box ATPases	4
Highlight: chemical biology of ion channels	4
Mycobacterial type VII secretion systems	4
Autophagic and non-autophagic functions of the Saccharomyces cerevisiae PROPPINs Atg18, Atg21 and Hsv2	4
Expanded profiling of β-lactam selectivity for penicillin-binding proteins in Streptococcus pneumoniae D39	4
A CK2α′ mutant indicating why CK2α and CK2α′, the isoforms of the catalytic subunit of human protein kinase CK2, deviate in affinity to CK2β	4
Comparison of human PEX knockout cell lines suggests a dual role of PEX1 in peroxisome biogenesis	4
Neprilysin 4: an essential peptidase with multifaceted physiological relevance	4
Epithelial-mesenchymal transition and H₂O₂ signaling – a driver of disease progression and a vulnerability in cancers	3
The human long non-coding RNA LINC00941 and its modes of action in health and disease	3
Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	3
Features of yeast RNA polymerase I with special consideration of the lobe binding subunits	3
Starting the engine of the powerhouse: mitochondrial transcription and beyond	3
Good things come to those who bait: the peroxisomal docking complex	3
The Rauischholzhausen Transport Colloquium: membrane proteins from structure to function	3
Nitazoxanide inhibits osteosarcoma cells growth and metastasis by suppressing AKT/mTOR and Wnt/β-catenin signaling pathways	3
Stress response pathways: machineries and mechanisms	3
The DEAD-box RNA helicase Dbp5 is a key protein that couples multiple steps in gene expression	3
Nanoscale organization of Ca_V2.1 splice isoforms at presynaptic terminals: implications for synaptic vesicle release and synaptic facilitation	3
Biochemical evidence for conformational variants in the anti-viral and pro-metastatic protein IFITM1	3
Frontmatter	3
The proteostasis burden of aneuploidy	3
Frontmatter	3
Highlight: Young research groups in Germany – 4th edition	3
GPI-anchored serine proteases: essential roles in development, homeostasis, and disease	3
Trispecific antibodies produced from mAb² pairs by controlled Fab-arm exchange	3
Heme research – the past, the present and the future	3
Synthesis of the ribosomal RNA precursor in human cells: mechanisms, factors and regulation	3
Time- and dose-dependent effects of CIGB-300 on the proteome of lung squamous cell carcinoma	3
Frontmatter	3
Molecular insights into endolysosomal microcompartment formation and maintenance	3
Unclogging of the TOM complex under import stress	3
A primer on heme biosynthesis	3
Felix Hoppe-Seyler (1825–1895): a pioneer in the field of biochemistry with many significant contributions to the development of the discipline	3
Microwave characterization of aqueous amino acid solutions using the multifrequency WGM resonator technique	3