OOIR: Observatory of International Research

Papers

(The TQCC of Biological Chemistry is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Antibody display technologies: selecting the cream of the crop	71
3-Mercaptopyruvate sulfurtransferase: an enzyme at the crossroads of sulfane sulfur trafficking	53
Shifting paradigms and novel players in Cys-based redox regulation and ROS signaling in plants - and where to go next	45
Kill one or kill the many: interplay between mitophagy and apoptosis	43
Regulation of DEAH-box RNA helicases by G-patch proteins	41
Acute-phase protein synthesis: a key feature of innate immune functions of the liver	34
Hsp70-mediated quality control: should I stay or should I go?	33
LncRNA ELFN1-AS1 promotes esophageal cancer progression by up-regulating GFPT1 via sponging miR-183-3p	33
Metabolism of non-growing bacteria	33
PINK1 and Parkin: team players in stress-induced mitophagy	32
Human islet amyloid polypeptide (hIAPP) - a curse in type II diabetes mellitus: insights from structure and toxicity studies	32
The MICOS complex, a structural element of mitochondria with versatile functions	31
Thiol switches in membrane proteins - Extracellular redox regulation in cell biology	30
Glutaredoxins and iron-sulfur protein biogenesis at the interface of redox biology and iron metabolism	30
Thiol-based redox switches in the major pathogen Staphylococcus aureus	30
Apoptosis inducing factor and mitochondrial NADH dehydrogenases: redox-controlled gear boxes to switch between mitochondrial biogenesis and cell death	30
The role of mitochondrial ATP synthase in cancer	29
Regulation of mitochondrial plasticity by the i-AAA protease YME1L	29
Unexpected metabolic versatility among type II methanotrophs in the Alphaproteobacteria	28
The role of very long chain fatty acids in yeast physiology and human diseases	28
DASH-type cryptochromes – solved and open questions	28
Emerging roles for non-selenium containing ER-resident glutathione peroxidases in cell signaling and disease	27
Citrate synthase desuccinylation by SIRT5 promotes colon cancer cell proliferation and migration	27
The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient	26
New horizons in mitochondrial contact site research	24

Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer’s disease	24
Marked difference in efficiency of the digestive enzymes pepsin, trypsin, chymotrypsin, and pancreatic elastase to cleave tightly folded proteins	22
Multicellular and unicellular responses of microbial biofilms to stress	22
Glutamine synthetase as a central element in hepatic glutamine and ammonia metabolism: novel aspects	21
Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function	21
Redox regulation in host-pathogen interactions: thiol switches and beyond	21
RNA secondary structure dependence in METTL3–METTL14 mRNA methylation is modulated by the N-terminal domain of METTL3	21
Pathomechanisms in hepatic encephalopathy	21
Redox-dependent and independent effects of thioredoxin interacting protein	21
Modular assembly of yeast mitochondrial ATP synthase and cytochrome oxidase	20
Diversity of GPI-anchored fungal adhesins	19
Chemerin – exploring a versatile adipokine	19
A progesterone receptor membrane component 1 antagonist induces large vesicles independent of progesterone receptor membrane component 1 expression	19
Biosynthesis and function of cell-surface polysaccharides in the social bacterium Myxococcus xanthus	19
Detecting myocardial scar using electrocardiogram data and deep neural networks	18
ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis	17
Hsa-miR-186-5p regulates TGFβ signaling pathway through expression suppression of SMAD6 and SMAD7 genes in colorectal cancer	17
Starting the engine of the powerhouse: mitochondrial transcription and beyond	17
LOTUS-domain proteins - developmental effectors from a molecular perspective	17
Investigation of the structure of regulatory proteins interacting with glycosaminoglycans by combining NMR spectroscopy and molecular modeling – the beginning of a wonderful friendship	16
Post-translational lysine ac(et)ylation in health, ageing and disease	15
Proteostasis in thermogenesis and obesity	15
Biochemical unity revisited: microbial central carbon metabolism holds new discoveries, multi-tasking pathways, and redundancies with a reason	15
The DEAH helicase DHX36 and its role in G-quadruplex-dependent processes	15
Regulation of RNA helicase activity: principles and examples	15
Revisiting the interaction of heme with hemopexin	14
Collagen/glycosaminoglycan-based matrices for controlling skin cell responses	14
A guide to designing photocontrol in proteins: methods, strategies and applications	14
iMLP, a predictor for internal matrix targeting-like sequences in mitochondrial proteins	14
Cyclic di-GMP signaling controlling the free-living lifestyle of alpha-proteobacterial rhizobia	14
Hepatic stellate cells: current state and open questions	14
An RNA-centric view on gut Bacteroidetes	14
High-mobility group box 3 (HMGB3) silencing inhibits non-small cell lung cancer development through regulating Wnt/β-catenin pathway	14
Generating asymmetry in a changing environment: cell cycle regulation in dimorphic alphaproteobacteria	14
Porins as helpers in mitochondrial protein translocation	14
Influence of monovalent metal ions on metal binding and catalytic activity of the 10–23 DNAzyme	14
Dead or alive: DEAD-box ATPases as regulators of ribonucleoprotein complex condensation	13
HDAC8 promotes daunorubicin resistance of human acute myeloid leukemia cells via regulation of IL-6 and IL-8	12
A primer on heme biosynthesis	12
Irisin ameliorates endoplasmic reticulum stress and liver fibrosis through inhibiting PERK-mediated destabilization of HNRNPA1 in hepatic stellate cells	12
Transfer RNA processing – from a structural and disease perspective	12
Regulation of RNA stability at the 3′ end	12
New insights into the role of glycosaminoglycans in the endosteal bone microenvironment	12
Thioredoxin-dependent control balances the metabolic activities of tetrapyrrole biosynthesis	11
The role of mycotoxins in neurodegenerative diseases: current state of the art and future perspectives of research	11
TFAP2A-induced SLC2A1-AS1 promotes cancer cell proliferation	11
Heme delivery to heme oxygenase-2 involves glyceraldehyde-3-phosphate dehydrogenase	11
Osteopontin enhances the migration of lung fibroblasts via upregulation of interleukin-6 through the extracellular signal-regulated kinase (ERK) pathway	11
New roles for GAPDH, Hsp90, and NO in regulating heme allocation and hemeprotein function in mammals	11
Thiol-based switching mechanisms of stress-sensing chaperones	11

Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells	11
Chemically modified glycosaminoglycan derivatives as building blocks for biomaterial coatings and hydrogels	11
Genomic insights into cyanobacterial protein translocation systems	11
Genetically encoded thiol redox-sensors in the zebrafish model: lessons for embryonic development and regeneration	11
Mtr4 RNA helicase structures and interactions	11
Structures and nucleic acid-binding preferences of the eukaryotic ARID domain	11
Membrane damage and repair: a thin line between life and death	10
Rational approaches towards inorganic and organometallic antibacterials	10
Small dense low-density lipoprotein-lowering agents	10
Expansion and inflammation of white adipose tissue - focusing on adipocyte progenitors	10
Redefining proteostasis transcription factors in organismal stress responses, development, metabolism, and health	10
Improvement of wound healing by the development of ECM-inspired biomaterial coatings and controlled protein release	10
Pseudomonas aeruginosa and Staphylococcus aureus virulence factors as biomarkers of infection	10
Structural insights into the modulation of PDGF/PDGFR-β complexation by hyaluronan derivatives	10
Spatial organization enhances versatility and specificity in cyclic di-GMP signaling	9
Physiology of guanosine-based second messenger signaling in Bacillus subtilis	9
PCAT1 induced by transcription factor YY1 promotes cholangiocarcinoma proliferation, migration and invasion by sponging miR-216a-3p to up-regulate oncogene BCL3	9
The role of host heme in bacterial infection	9
STAT3 promotes peritoneal metastasis of gastric cancer by enhancing mesothelial-mesenchymal transition	9
Molecular mechanisms of vasculopathy and coagulopathy in COVID-19	9
DDX41: a multifunctional DEAD-box protein involved in pre-mRNA splicing and innate immunity	9
CERKL alleviates ischemia reperfusion-induced nervous system injury through modulating the SIRT1/PINK1/Parkin pathway and mitophagy induction	9
The paracaspase MALT1 in psoriasis	9
Emerging contributions of formyl peptide receptors to neurodegenerative diseases	9
Characterization of a fluorescent 1,8-naphthalimide-functionalized PAMAM dendrimer and its Cu(ii) complexes as cytotoxic drugs: EPR and biological studies in myeloid tumor cells	8
Decreased level of miR-1301 promotes colorectal cancer progression via activation of STAT3 pathway	8
Elucidating the anti-biofilm and anti-quorum sensing potential of selenocystine against respiratory tract infections causing bacteria: in vitro and in silico studies	8
Histone deacetylase 1 regulates the malignancy of oral cancer cells via miR-154-5p/PCNA axis	8
Assessment of the breadth of binding promiscuity of heme towards human proteins	8
Molecular insights into endolysosomal microcompartment formation and maintenance	8
Vorinostat exhibits anticancer effects in triple-negative breast cancer cells by preventing nitric oxide-driven histone deacetylation	8
Modulation of macrophage functions by ECM-inspired wound dressings – a promising therapeutic approach for chronic wounds	8
Identification of cytokeratin24 as a tumor suppressor for the management of head and neck cancer	8
Exceptionally versatile take II: post-translational modifications of lysine and their impact on bacterial physiology	8
Epithelial-mesenchymal transition and H₂O₂ signaling – a driver of disease progression and a vulnerability in cancers	8
The role of the Na⁺/Ca²⁺-exchanger (NCX) in cancer-associated fibroblasts	8
Zinc-dependent changes in oxidative and endoplasmic reticulum stress during cardiomyocyte hypoxia/reoxygenation	8
Placental mitochondrial function as a driver of angiogenesis and placental dysfunction	8
Individual and combined effects of GIP and xenin on differentiation, glucose uptake and lipolysis in 3T3-L1 adipocytes	8
Transcription, translation, and DNA repair: new insights from emerging noncanonical substrates of RNA helicases	8