Clinical Chemistry and Laboratory Medicine

Article	Citations
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of primidone in human serum and plasma	82
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of gabapentin in human serum and plasma	75
Interest of minigene splicing reporter assay in familial hypobetalipoproteinemia genetic diagnosis: the example of the missense mutation APOB c.1468C>T	75
Comparison of the QuikRead go® point-of-care faecal immunochemical test for haemoglobin with the FOB Gold Wide® laboratory analyser to diagnose colorectal cancer in symptomatic p	72
43rd annual conference of the association of clinical biochemists in Ireland (ACBI 2021)	64
Interest of hair tests to discriminate a tail end of a doping regimen from a possible unpredictable source of a prohibited substance in case of challenging an anti-doping rule violation	56
EFLM Task Force Preparation of Labs for Emergencies (TF-PLE) recommendations for reinforcing cyber-security and managing cyber-attacks in medical laboratories	54
Evaluation of AUTION EYE AI-4510 flow cell morphology analyzer for counting particles in urine	54
The correlation of albumin with total protein concentrations in cerebrospinal fluid across three automated analysers – relevance to the diagnosis of subarachnoid haemorrhage in clinical chemistry prac	50
Absolute quantitation of human serum cystatin C: candidate reference method by 15N-labeled recombinant protein isotope dilution UPLC-MS/MS	47
Diagnostic performances and cut-off verification of blood pTau 217 on the Lumipulse platform for amyloid deposition in Alzheimer’s disease	41
Frontmatter	40
Exploring the extent of post-analytical errors, with a focus on transcription errors – an intervention within the VIPVIZA study	39
Effects of different pepsinogen cut offs in the screening of apparently healthy people	39
Quality indicators in laboratory medicine: a 2020–2023 experience in a Chinese province	39
Monocyte distribution width (MDW): study of reference values in blood donors	38
Acetylcholine receptor and muscle-specific tyrosine kinase antibodies detection: is it time for a change?	38
Monocyte distribution width (MDW) as a reliable biomarker for urosepsis	36
Deciphering the role of monocyte and monocyte distribution width (MDW) in COVID-19: an updated systematic review and meta-analysis	36
Effect of preexamination conditions in a centralized-testing model of non-invasive prenatal screening	35
Personalised Medicine, including pharmacogenetics	35
EFLM Symposium - Quality in clinical laboratory: a moving target	35
Digital health, big data and smart technologies	34
Laboratory Management	34
Symposium 5 - Autoimmune Diseases	33

EFLM Symposium - Precision Medicine	32
Green laboratories	31
Inflammation, vascular biology, endothelium, and oxidative stress	31
Miscellaneous	31
Cardiovascular diseases and cardiac biomarkers	31
Symposium 7 - Young Scientist Session	30
IFCC Symposium - Artificial intelligence applications in clinical laboratory medicine	30
Educational Workshops Abstracts	29
Plenary 4 - Diagnostic advances in dementia	29
Clinical cases – Preanalytical mysteries	29
Two co-inherited hemoglobin variants revealed by capillary electrophoresis during quantification of glycated hemoglobin	27
Simple steps to achieve harmonisation and standardisation of dried blood spot phenylalanine measurements and facilitate consistent management of patients with phenylketonuria	26
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms: a systematic review of the literature	26
Inclusion of pyridoxine dependent epilepsy in expanded newborn screening programs by tandem mass spectrometry: set up of first and second tier tests	26
Prognostic value of anti-SARS-CoV-2 antibodies: a systematic review	26
Biomarkers in cancer	25
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of cortisol in human serum and plasma	25
Lumipulse G SARS-CoV-2 Ag assay evaluation using clinical samples from different testing groups	23
Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the	23
CSF-interleukin 6 for early diagnosis of ventriculitis in a broad intensive care setting	22
Stability of lactate in venous blood gas and sodium fluoride-potassium oxalate plasma: a 6-year retrospective database analysis	22
In reply to: Limitations in using the EFLM WG-A/ISO approach for assessment of reagent lot variability	22
Pancreatic lipase: why laboratory community does not take enough care of this clinically important test?	22
Biological variation estimates obtained from Chinese subjects for 32 biochemical measurands in serum	21
Harmonization status of procalcitonin measurements: what do comparison studies and EQA schemes tell us?	21
Proenkephalin A 119–159 (penKid) – a novel biomarker and its quantification on the Nexus IB10 POC system for assessing kidney function	21
The underestimated potential of vibrational spectroscopy in clinical laboratory medicine: a translational gap to close	21
Assessment of humoral and cellular immunity after bivalent BNT162b2 vaccination and potential association with reactogenicity	21
A novel scoring system combining Modified Early Warning Score with biomarkers of monocyte distribution width, white blood cell counts, and neutrophil-to-lymphocyte ratio to improve early sepsis predic	20
Overcoming challenges regarding reference materials and regulations that influence global standardization of medical laboratory testing results	20
Direct-to-consumer testing – benefits for consumers, people with disease and public health	20
Aggregated data from the same laboratories participating in two glucose external quality assessment schemes show that commutability and transfers of values to control materials are decisive for the bi	20
Complexity of serological assays and misunderstandings of WHO International Units	20
Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation	20
How to evaluate fixed clinical QC limits vs. risk-based SQC strategies	19
Novel Mindray high sensitivity cardiac troponin I assay for single sample and 0/2-hour rule out of myocardial infarction: MERITnI study	19
Moving average quality control of routine chemistry and hematology parameters – a toolbox for implementation	19
Toxicology, including therapeutic drug monitoring	19
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of zonisamide in human serum and plasma	19
A simulation model for organization and management skills assessment that meets ISO 15189	19
Statistics in diagnostic medicine	18
Validation of ELISA assays for the calculation of FLC indices for the diagnosis of intrathecal immunoglobulin synthesis	18
Evaluation of ichroma™ COVID-19 interferon gamma release assay for detection of vaccine-induced immunity in healthcare workers	18
Anti-Ki/anti-PA28γ autoantibodies contribute to the HEp-2 indirect immunofluorescence nuclear speckled pattern	18
Notification of biochemistry critical results and its clinical impact on outpatient care: experience in a Spanish tertiary hospital	18
Discriminating signal from noise: the biological variation of circulating calprotectin in serum and plasma	18
Web-accessible critical limits and critical values for urgent clinician notification	17
Measurement uncertainty estimation of free drug concentrations in clinical laboratories using equilibrium dialysis	17
Total Testing Process, including standardisation, preanalytical process	17
Reference intervals of 24 trace elements in blood, plasma and erythrocytes for the Slovenian adult population	17

Standardisation and harmonisation of thyroid-stimulating hormone measurements: historical, current, and future perspectives	17
What could cause a false increase in serum C-reactive protein concentration?	17
Circulating tumor DNA measurement: a new pillar of medical oncology?	17
Diagnostic performance of a point of care high-sensitivity cardiac troponin I assay and single measurement evaluation to rule out and rule in acute coronary syndrome	17
Frontmatter	17
Analytical evaluation of a GAD65 antibodies chemiluminescence immunoassay for CSF in neurological syndromes	17
Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China	17
Ligand binding assay-related underestimation of 25-hydroxyvitamin D in pregnant women exaggerates the prevalence of vitamin D insufficiency	16
60th National Congress of the Hungarian Society of Laboratory Medicine	16
Hypertriglyceridemia, a causal risk factor for atherosclerosis, and its laboratory assessment	16
The clinical significance of the peritoneal dialysis evaluation test in the Department of Laboratory Medicine	16
Reply to Abildgaard et al.: lot variation and inter-device differences contribute to poor analytical performance of the DCA vantage™ HbA1cPOCT instrument in a true clinical setting	16
Prognostic significance of smudge cell percentage in chronic lymphocytic leukemia. Facts or artifacts? Methodological considerations and literature review	16
Covert poisoning with difenacoum: diagnosis and follow-up difficulties	16
Frontmatter	16
4th National Point of Care Testing Symposium	16
TSH-receptor autoantibodies in patients with chronic thyroiditis and hypothyroidism	16
Frontmatter	16
The European Register of Specialists in Clinical Chemistry and Laboratory Medicine: code of conduct, version 3 – 2023	15
About the estimation of albuminuria based on proteinuria results	15
Seroprevalence of SARS-CoV-2 antibodies in Italy in newborn dried blood spots	15
C-reactive protein interacts with amphotericin B liposomes and its potential clinical consequences	15
Coagulation parameters in the newborn and infant – the Copenhagen Baby Heart and COMPARE studies	15
Presepsin levels in neonatal cord blood are not influenced by maternal SARS-CoV-2 infection	15
Frontmatter	15
Frozen serum sample pool should not be used as internal quality assessment for lipemia (L) index	15
A new method for early cancer detection based on platelet transcriptomics will have low positive predictive value	15
Limitations in using the EFLM WG-A/ISO approach for assessment of reagent lot variability	15
9th Annual Meeting of the Austrian Society for Laboratory Medicine and Clinical Chemistry (ÖGLMKC)	15
Recent advances in laboratory hematology reflected by a decade of CCLM publications	15
Reply to: “Is uracil enough for effective pre-emptive DPD testing?”	15
Patient result monitoring of HbA1c shows small seasonal variations and steady decrease over more than 10 years	15
Non-esterified fatty acids (NEFA): sample stability and effect of haemolysis and icterus	15
Diagnostic performance of machine learning models using cell population data for the detection of sepsis: a comparative study	14
Within- and between-subject biological variation data for serum zinc, copper and selenium obtained from 68 apparently healthy Turkish subjects	14
Comparison of four indirect (data mining) approaches to derive within-subject biological variation	14
Pre-analytical considerations for the analysis of uracil and 5,6-dihydrouracil in heparin plasma	14
Higher troponin T serum concentrations in hospital patients without diagnosed cardiac diseases compared to a population-based cohort	14
Clinical applications of circulating tumor cell detection: challenges and strategies	14
Blood sampling frequency as a proxy for comorbidity indices when identifying patient samples for review of reference intervals	14
Labile glycated hemoglobin: an underestimated laboratory marker of short term glycemia	14
The chitinases as biomarkers in immune-mediate diseases	14
Monocyte distribution width (MDW) as a screening tool for early detecting sepsis: a systematic review and meta-analysis	14
Misdiagnosis of Hb Bart’s disease: prenatal screening and diagnosis of thalassemia in special population	13
A comparative analysis of current С-peptide assays compared to a reference method: can we overcome inertia to standardization?	13
Long-term stability of 25-hydroxyvitamin D: importance of the analytical method and of the patient matrix	13
The importance of correct stratifications when comparing directly and indirectly estimated reference intervals	13
Navigating between perpendicular drop and tangent skimming methods for M-protein quantification: a call for clarification of guidelines	13
Indirectly determined reference intervals for automated white blood cell differentials of pediatric patients in Berlin and Brandenburg	13
Serial measurement of circulating calprotectin as a prognostic biomarker in COVID-19 patients in intensive care setting	13
Impact of storage temperature and time before analysis on electrolytes (Na+, K+, Ca2+), lactate, glucose, blood gases (pH, pO2, pCO2), tHb, O	13
Reply to: Spurious results for total and free prostate-specific antigen (PSA); sometimes really “a riddle wrapped in a mystery inside an enigma”	13
Letter to the Editor regarding the article by Wayne J. Dimech et al. Time to address quality control processes applied to antibody testing for infectious diseases. Clin Chem Lab Med 2023; 61(2):205–21	13
Effects of lipemia on capillary serum protein electrophoresis in native ultra-lipemic material and intravenous lipid emulsion added sera	13
Evaluation of the analytical and clinical performance of a new high-sensitivity cardiac troponin I assay: hs-cTnI (CLIA) assay	12
APS calculator: a data-driven tool for setting outcome-based analytical performance specifications for measurement uncertainty using specific clinical requirements and population data	12
Development of a candidate reference measurement procedure by ID-LC-MS/MS for total tau protein measurement in cerebrospinal fluid (CSF)	12
Artificial base mismatches-mediated PCR (ABM-PCR) for detecting clinically relevant single-base mutations	12
Recommendations for IVDR compliant in-house software development in clinical practice: a how-to paper with three use cases	12
Health Technology Assessment to assess value of biomarkers in the decision-making process	12
Design of an algorithm for the detection of intravenous fluid contamination in clinical laboratory samples	12
Monocyte distribution width as an early predictor of short-term outcome in adult patients with sepsis	12
The correlation of urea and creatinine concentrations in sweat and saliva with plasma during hemodialysis: an observational cohort study	12
Anti-phosphatidyl-serine/prothrombin antibodies (aPS/PT) in isolated lupus anticoagulant (LA): is their presence linked to dual test positivity?	12
Laboratory medicine in the COVID-19 era: six lessons for the future	12
Diagnostic performance of the fully automated Roche Elecsys SARS-CoV-2 antigen electrochemiluminescence immunoassay: a pooled analysis	12
Chatbot GPT can be grossly inaccurate	12
Rapid rule-in and rule-out protocols of acute myocardial infarction using hs-cTnI and hs-cTnT methods	12
Case report	11
Quantitative profiling of inflammatory and pro-resolving lipid mediators in human adolescents and mouse plasma using UHPLC-MS/MS	11
Allergy: Evaluation of 16 years (2007–2022) results of the shared external quality assessment program in Belgium, Finland, Portugal and The Netherlands	11
Evaluation of analytical performance of homocysteine LC-MS/MS assay and design of internal quality control strategy	11
Amino acid sequence homology of monoclonal serum free light chain dimers and tissue deposited light chains in AL amyloidosis: a pilot study	11
Diagnostic utility of pleural cell-free nucleic acids in undiagnosed pleural effusions	11
Analysis of cryoproteins with a focus on cryofibrinogen: a study on 103 patients	11
Accurate non-ceruloplasmin bound copper: a new biomarker for the assessment and monitoring of Wilson disease patients using HPLC coupled to ICP-MS/MS	11
Low free-T3 serum levels and prognosis of COVID-19: systematic review and meta-analysis	11
The EU Green Deal: the challenge of greening medical technologies	11
Circulating pro-gastrin releasing peptide (ProGRP) in patients with medullary thyroid carcinoma	11
Cell population data: much more to explore	11

The stability of C-peptide and insulin in plasma and serum samples under different storage conditions	11
Repository of intra- and inter-run variations of quantitative autoantibody assays: a European multicenter study	11
Crioplast® is a reliable device to ensure pre-analytical stability of adrenocorticotrophin (ACTH)	11
Reliable detection of sex chromosome abnormalities by quantitative fluorescence polymerase chain reaction	11
Machine learning to optimize cerebrospinal fluid dilution for analysis of MRZH reaction	11
Effect of BNT162b2 booster dose on anti-SARS-CoV-2 spike trimeric IgG antibodies in seronegative individuals	11
Drone transport of biological samples: an open issue	11
Integration of artificial intelligence and plasma steroidomics with laboratory information management systems: application to primary aldosteronism	11
Targeted quantitative lipidomic uncovers lipid biomarkers for predicting the presence of compensated cirrhosis and discriminating decompensated cirrhosis from compensated cirrhosis	11
Machine learning-based delta check method for detecting misidentification errors in tumor marker tests	10
Implementation and challenges of portable blood gas measurements in air medical transport	10
Quantitative serological evaluation as a valuable tool in the COVID-19 vaccination campaign	10
Direct-to-consumer testing as consumer initiated testing: compromises to the testing process and opportunities for quality improvement	10
Urinary exosomal CD26 is associated with recovery from acute kidney injury in intensive care units: a prospective cohort study	10
Patients with severe COVID-19 do not have elevated autoantibodies against common diagnostic autoantigens	10
Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark	10
Analytical validation of the amplification refractory mutation system polymerase chain reaction-capillary electrophoresis assay to diagnose spinal muscular atrophy	10
Machine learning-based nonlinear regression-adjusted real-time quality control modeling: a multi-center study	10
Pediatric reference interval verification for endocrine and fertility hormone assays on the Abbott Alinity system	10
EN ISO 15189 revision: EFLM Committee Accreditation and ISO/CEN standards (C: A/ISO) analysis and general remarks on the changes	10
Isotope dilution LC-MS/MS quantification of the cystic fibrosis transmembrane conductance regulator (CFTR) modulators ivacaftor, lumacaftor, tezacaftor, elexacaftor, and their major metabolites in hum	10
Clostebol and sport: about controversies involving contamination vs. doping offence	10
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of aldosterone in human serum and plasma	10
Analytical verification of the Atellica VTLi point of care high sensitivity troponin I assay	10
Effects of storage conditions on the stability of blood-based markers for the diagnosis of Alzheimer’s disease	10
The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy	10
Simple flow cytometry method using a myeloma panel that easily reveals clonal proliferation of mature B-cells	10
Stability of SARS-CoV-2 respiratory samples in non-freezing condition: importance for tropical countries under heavy diagnostic demand	10
External quality assessment-based tumor marker harmonization simulation; insights in achievable harmonization for CA 15-3 and CEA	10
Reference intervals of 14 biochemical markers for children and adolescence in China: the PRINCE study	10
Analytical performance specifications for trace elements in biological fluids derived from six countries federated external quality assessment schemes over 10 years	10
Detection of DNA copy number alterations by matrix-assisted laser desorption/ionization time-of-flight mass spectrometric analysis of single nucleotide polymorphisms	10
Clinical specificity of two assays for immunoglobulin kappa and lambda free light chains	10
Get reliable laboratory findings – how to recognize the deceptive effects of angiotensin-converting enzyme inhibitor therapy in the laboratory diagnostics of sarcoidosis?	10
External quality assessment for detection of methylated Syndecan 2 (SDC2) in China	9
Theranos revisited: the trial and lessons learned	9
Individual risk prediction of high grade prostate cancer based on the combination between total prostate-specific antigen (PSA) and free to total PSA ratio	9
Adherence to recommendations and clinical practice guidelines: not an easy task	9
Analysis of a second-tier test panel in dried blood spot samples using liquid chromatography-tandem mass spectrometry in Catalonia’s newborn screening programme	9
A promising new direct immunoassay for urinary free cortisol determination	9
Quantitation of cardiac troponin I in cancer patients treated with immune checkpoint inhibitors: a case-control study	9
Results of a SARS-CoV-2 virus genome detection external quality assessment round focusing on sensitivity of assays and pooling of samples	9
A novel LC-MS/MS-based assay for the simultaneous quantification of aldosterone-related steroids in human urine	9
Neonatal lymphocyte subpopulations analysis and maternal preterm premature rupture of membranes: a pilot study	9
How to best use procalcitonin to diagnose infections and manage antibiotic treatment	9
New generation of Abbott enzyme assays: imprecision, methods comparison, and impact on patients’ results	9
Neutralizing antibody titers six months after Comirnaty vaccination: kinetics and comparison with SARS-CoV-2 immunoassays	9
A reactive monocyte subset characterized by low expression of CD91 is expanded during sterile and septic inflammation	9
Recommendation for the design of stability studies on clinical specimens	9
Knowledge among clinical personnel on the impact of hemolysis using blood gas analyzers	9
Three rounds of a national external quality assessment reveal a link between disharmonic anti-SARS-CoV-2 antibody quantifications and the infection stage	9
Preanalytical quality improvement – an interdisciplinary journey	9
Assessing vitamin D metabolism – four decades of experience	9
Biomarkers in the management of lung cancer: changing the practice of thoracic oncology	9
Health literacy: a new challenge for laboratory medicine	9
Blood lactate concentration in COVID-19: a systematic literature review	9
Plasmacytoid dendritic cell proliferation and acute myeloid leukemia with minimal differentiation (AML-M0)	9
Clinical lipidomics in the era of the big data	9
Analytical and clinical evaluations of SNIBE Maglumi chemiluminescent immunoassay for the detection of SARS-CoV-2 antigen in salivary samples	9
Disruption vs. evolution in laboratory medicine. Current challenges and possible strategies, making laboratories and the laboratory specialist profession fit for the future	9
Increased specificity of the “GFAP/UCH-L1” mTBI rule-out test by age dependent cut-offs	9
External quality assessment providers’ services appear to more impact the immunohaematology performance of laboratories than national regulatory and economic conditions	9
COVID-19	9
The influence of undetected hemolysis on POCT potassium results in the emergency department	8
Evaluating the accuracy of ChatGPT in classifying normal and abnormal blood cell morphology	8
Multicenter study to compare the diagnostic performance of CLIA vs. FEIA transglutaminase IgA assays for the diagnosis of celiac disease	8
Point-of-care testing, near-patient testing and patient self-testing: warning points	8
Within-subject biological variation estimates using an indirect data mining strategy. Spanish multicenter pilot study (BiVaBiDa)	8
The stability of pleural fluid pH under slushed ice and room temperature conditions	8
Direct-to-consumer laboratory testing (DTCT): challenges and implications for specialists in laboratory medicine	8
Response to Tony Badrick regarding “Letter to the Editor regarding the article by Wayne J. Dimech et al. Time to address quality control processes applied to antibody testing for infectious diseases.	8
The impact of physiological variations on personalized reference intervals and decision limits: an in-depth analysis	8
Machine learning-based clinical decision support using laboratory data	8
Description and validation of an equilibrium dialysis ID-LC-MS/MS candidate reference measurement procedure for free thyroxine in human serum	8
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA)	8
A comprehensive survey of artificial intelligence adoption in European laboratory medicine: current utilization and prospects	8
Behind the scenes of EQA–characteristics, capabilities, benefits and assets of external quality assessment (EQA)	8
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays	8
Development of a liquid chromatography mass spectrometry method for the determination of vitamin K1, menaquinone-4, menaquinone-7 and vitamin K1-2,3 epoxide in serum of individuals without vitamin K s	8
IVDCheckR – simplifying documentation for laboratory developed tests according to IVDR requirements by introducing a new digital tool	8
Frontmatter	8
Diagnostic potential of leukocyte differential and cell population data in prediction of COVID-19 among related viral and bacterial infections at Emergency Department	8
A vision to the future: value-based laboratory medicine	8
Pseudohyperglycemia due to glucometer interference in galactosemia	8
Biological variation estimates of thyroid related measurands – meta-analysis of BIVAC compliant studies	8
Confounding factors of the expression of mTBI biomarkers, S100B, GFAP and UCH-L1 in an aging population	8
Frontmatter	8
Concentrations and agreement over 10 years with different assay versions and analyzers for troponin T and N-terminal pro-B-type natriuretic peptide	8
Not all biases are created equal: how to deal with bias on laboratory measurements	8
Microbiology - Infectious diseases including COVID 19	8
Second-generation Elecsys cerebrospinal fluid immunoassays aid diagnosis of early Alzheimer’s disease	8
Lot-to-lot reagent changes and commutability of quality testing materials for total bile acid measurements	8
Serum hepcidin levels in chronic liver disease: a systematic review and meta-analysis	8
Reference ranges for GDF-15, and risk factors associated with GDF-15, in a large general population cohort	8
Bland and Altman agreement method: to plot differences against means or differences against standard? An endless tale?	8