Clinical Chemistry and Laboratory Medicine

Article	Citations
Performance of the 2009 CKDEPI, 2021 CKDEPI, and EKFC equations among high-risk patients in Denmark	99
Plenary 4 - Diagnostic advances in dementia	90
Analytical performance specifications for trace elements in biological fluids derived from six countries federated external quality assessment schemes over 10 years	89
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure (RMP) for the quantification of aldosterone in human serum and plasma	87
Evaluation of the analytical and clinical performance of a new high-sensitivity cardiac troponin I assay: hs-cTnI (CLIA) assay	73
Presence of SARS-CoV-2 RNA in COVID-19 survivors with post-COVID symptoms: a systematic review of the literature	68
Moving average quality control of routine chemistry and hematology parameters – a toolbox for implementation	58
Design of an algorithm for the detection of intravenous fluid contamination in clinical laboratory samples	51
Development of a liquid chromatography mass spectrometry method for the determination of vitamin K1, menaquinone-4, menaquinone-7 and vitamin K1-2,3 epoxide in serum of individuals without vitamin K s	49
Diagnostic performance of a point of care high-sensitivity cardiac troponin I assay and single measurement evaluation to rule out and rule in acute coronary syndrome	49
ROUND-TABLE 1 - Beyond the Numbers: Integrating Laboratory and Clinical Perspectives on Thyroid Health	47
Frontmatter	47
SYMPOSIUM 7 - Medical test standardization in the era of Metrological Traceability: who is accountable?	47
Web-accessible critical limits and critical values for urgent clinician notification	41
Quantification of blood glial fibrillary acidic protein using a second-generation microfluidic assay. Validation and comparative analysis with two established assays	38
EN ISO 15189 revision: EFLM Committee Accreditation and ISO/CEN standards (C: A/ISO) analysis and general remarks on the changes	38
Coagulation parameters in the newborn and infant – the Copenhagen Baby Heart and COMPARE studies	38
Machine learning-based delta check method for detecting misidentification errors in tumor marker tests	38
Not all biases are created equal: how to deal with bias on laboratory measurements	38
Discriminating signal from noise: the biological variation of circulating calprotectin in serum and plasma	37
Multiplex proteomics using proximity extension assay for the identification of protein biomarkers predictive of acute graft-vs.-host disease in allogeneic hematopoietic cell transplantation	36
Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the	36
Serial measurement of circulating calprotectin as a prognostic biomarker in COVID-19 patients in intensive care setting	35
Results of a SARS-CoV-2 virus genome detection external quality assessment round focusing on sensitivity of assays and pooling of samples	34
Diagnostic performance of machine learning models using cell population data for the detection of sepsis: a comparative study	34

A novel LC-MS/MS-based assay for the simultaneous quantification of aldosterone-related steroids in human urine	33
From assessment to action: experience from a quality improvement initiative integrating indicator evaluation and adverse event analysis in a clinical laboratory	31
Multicenter study to compare the diagnostic performance of CLIA vs. FEIA transglutaminase IgA assays for the diagnosis of celiac disease	31
Measurement uncertainty estimation of free drug concentrations in clinical laboratories using equilibrium dialysis	31
An automatic chemiluminescence immunoassay for a novel biomarker NT-IGFBP-4: analytical performance and clinical relevance in heart failure	31
Behind the scenes of EQA – characteristics, capabilities, benefits and assets of external quality assessment (EQA): Part II – EQA cycles	30
Overcoming challenges regarding reference materials and regulations that influence global standardization of medical laboratory testing results	30
Acetylcholine receptor and muscle-specific tyrosine kinase antibodies detection: is it time for a change?	30
Insight into the status of plasma renin and aldosterone measurement: findings from 526 clinical laboratories in China	29
Monocyte distribution width (MDW) as a screening tool for early detecting sepsis: a systematic review and meta-analysis	29
Preanalytical quality improvement – an interdisciplinary journey	29
Cell population data: much more to explore	28
COVID-19	28
Interference of therapeutic monoclonal antibodies with electrophoresis and immunofixation of serum proteins: state of knowledge and systematic review	27
Statistics in diagnostic medicine	27
Epigenetic signatures of cfDNA enable a topological assignment of tissue damage	26
Evaluation of biochemical algorithms to screen dysbetalipoproteinemia in ε2ε2 and rare APOE variants carriers	26
Frontmatter	26
Reference intervals and decision limits	25
Frontmatter	25
Precision Medicine	24
ISMD2024 Thirteenth International Symposium on Molecular Diagnostics	24
Kidney diseases and transplantation, urinanalysis	24
The 10+1 Santorini Conference	24
53rd National Congress of the Italian Society of Clinical Biochemistry and Clinical Molecular Biology (SIBioC – Laboratory Medicine)	23
Clinical Studies - Outcomes	23
Biological matrices, reagents and turnaround-time: the full-circle of artificial intelligence in the pre-analytical Phase. Comment on Turcic A, et al., Machine learning to optimize cerebrospinal fluid	23
Comparison of near-infrared and UV–vis-based non-contact hematocrit prediction of dried blood spots from patients on immunosuppressants	22
Laboratory response to paradigm change in hemophilia treatment	22
Neonatal reference intervals for serum steroid hormone concentrations measured by LC-MS/MS	22
Clinical utility of personalized reference intervals for CEA in the early detection of oncologic disease	21
IgA rheumatoid factor in rheumatoid arthritis	21
Microbiology - Infectious diseases including COVID 19	21
Clinical evidence requirements according to the IVDR 2017/746: practical tools and references for underpinning clinical evidence of IVD-MDs	21
Greater expectations: meeting clinical needs through broad and rapid genomic testing	21
Serum sPD-L1 levels are elevated in patients with viral diseases, bacterial sepsis or in patients with impaired renal function compared to healthy blood donors	21
What matters most: an age-friendly approach to pathology and laboratory medicine	21
Artificial intelligence in clinical applications for lung cancer: diagnosis, treatment and prognosis	21
Frontmatter	21
A single dose of 20-mg of ostarine is detectable in hair	21
An improved implementation of metrological traceability concepts is needed to benefit from standardization of laboratory results	21
The role of analytical performance specifications in international guidelines and standards dealing with metrological traceability in laboratory medicine	21
Regulating the future of laboratory medicine: European regulatory landscape of AI-driven medical device software in laboratory medicine	21
Analytical performance specifications – moving from models to practical recommendations	21
The impact of COVID-19 on citations of laboratory medicine journals	20
Biomarkers to measure the need and the effectiveness of therapeutic supplementation: a critical issue	20
A step forward in pediatric hemophagocytic lymphohistiocytosis and autoimmune disease: pediatric reference interval for serum soluble IL-2 receptor and soluble CD163	20
Biological variation of serum cholinesterase activity in healthy subjects	20
One fits all: a highly sensitive combined ddPCR/pyrosequencing system for the quantification of microchimerism after hematopoietic and solid organ transplantation	20
Dynamics of the vitamin D C3-epimer levels in preterm infants	20

Evaluation of effects from hemoglobin variants on HbA1c measurements by different methods	20
Pseudo-erythroblastosis on Sysmex XN hematology analyzers: a clue to Candida sepsis. Case report and literature review	19
International collaborative study to evaluate and calibrate two recombinant L chain Ferritin preparations for use as a WHO International Standard	19
Response to Tony Badrick regarding “Letter to the Editor regarding the article by Wayne J. Dimech et al. Time to address quality control processes applied to antibody testing for infectious diseases.	19
Emerging technology: a definition for laboratory medicine	19
Use of the term “Bence-Jones proteinuria” in the EFLM European Urinalysis Guideline 2023	19
Familial dysalbuminemic hyperthyroxinemia coexisting with a Grave’s disease: a Belgian case report	18
Long-term effects of interventions applied to optimize the use of 25-OH vitamin D tests in primary health care	18
Contents	18
Pseudohyperglycemia due to glucometer interference in galactosemia	18
External quality assurance (EQA): navigating between quality and sustainability	18
Refining within-subject biological variation estimation using routine laboratory data: practical applications of the refineR algorithm	18
HTA model for laboratory medicine technologies: overview of approaches adopted in some international agencies	18
Benchmarking medical laboratory performance: survey validation and results for Europe, Middle East, and Africa	17
Drainage fluid LDH and neutrophil to lymphocyte ratio as biomarkers for early detecting anastomotic leakage in patients undergoing colorectal surgery	17
Linearity assessment: deviation from linearity and residual of linear regression approaches	17
SYMPOSIUM 1 - New approaches for deriving and applying biological variation data for clinical use	17
Analytical evaluation of the novel Mindray high sensitivity cardiac troponin I immunoassay on CL-1200i	17
Concordance between the updated Elecsys cerebrospinal fluid immunoassays and amyloid positron emission tomography for Alzheimer’s disease assessment: findings from the Apollo study	17
Comprehensive evaluation of antiphospholipid antibody testing methodologies in APS diagnosis: performance comparisons across assay systems and clinical subtypes	17
Colorimetric correcting for sample concentration in stool samples	17
An isotope dilution-liquid chromatography-tandem mass spectrometry based candidate reference measurement procedure for the simultaneous quantification of 25-hydroxyvitamin D3 and 25-hydroxyvitamin D2	17
Stability of plasma renin concentration based on plasma freezing time, as an adjunct to the stability data reported in the paper by Hepburn and others	17
Diabetes, obesity, metabolic syndrome	16
Metrological traceability and test standardization/harmonization	16
Frontmatter	16
IgG and kappa free light chain CSF/serum indices: evaluating intrathecal immunoglobulin production in HIV infection in comparison with multiple sclerosis	16
Inherited disorders, metabolic disorders and rare diseases	16
Lot-to-lot reagent verification: challenges and possible solutions	16
A new milestone on the road to global standardization of apolipoprotein measurements	16
Cell population data for early detection of sepsis in patients with suspected infection in the emergency department	16
‘Penelope test’: a practical instrument for checking appropriateness of laboratory tests	16
Remote monitoring and preanalytical challenges	16
Lot variation and inter-device differences contribute to poor analytical performance of the DCA Vantage™ HbA1c POCT instrument in a true clinical setting	16
Quality in laboratory medicine and the Journal: walking together	16
Serous body fluid evaluation using the new automated haematology analyser Mindray BC-6800Plus	15
The role of Killer immunoglobulin-like receptors (KIRs) in the genetic susceptibility to non-celiac wheat sensitivity (NCWS)	15
Estimation of the reference values and decision limits for growth hormone in newborns using dried blood spots	15
Evaluation of reference intervals for classical and alternative pathway functional complement assays	15
Clinical evaluation of the OC-Sensor Pledia calprotectin assay	15
Performance evaluation and user experience of BT-50 transportation unit with automated and scheduled quality control measurements	15
Evaluation of the interchangeability between the new fully-automated affinity chrome-mediated immunoassay (ACMIA) and the Quantitative Microsphere System (QMS) with a CE-IVD-certified LC-MS/MS assay f	15
Comparison between polynomial regression and weighted least squares regression analysis for verification of analytical measurement range	15
The preanalytical process in the emergency department, a European survey	15
Reply to: “Accurate predictory role of monocyte distribution width on short-term outcome in sepsis patients”	15
Association of prehospital lactate levels with base excess in various emergencies – a retrospective study	15
Artificial intelligence - Informatics	14
Frontmatter	14
A physio-chemical mathematical model of the effects of blood analysis delay on acid-base, metabolite and electrolyte status: evaluation in blood from critical care patients	14
Validation and verification framework and data integration of biosensors and in vitro diagnostic devices: a position statement of the IFCC Committee on Mobile Health and Bioengineering in Labor	14
Assessing the clinical applicability of dimensionality reduction algorithms in flow cytometry for hematologic malignancies	14
Comparison of three different protocols for obtaining hemolysis	14
Frontmatter	14
Improving regional medical laboratory center report quality through a report recall management system	14
Flow-cytometric lymphocyte subsets enumeration: comparison of single/dual-platform method in clinical laboratory with dual-platform extended PanLeucogating method in reference laboratory	14
An isotope dilution-liquid chromatography-tandem mass spectrometry (ID-LC-MS/MS)-based candidate reference measurement procedure for the quantification of carbamazepine-10,11-epoxide in human serum an	14
Copeptin as a diagnostic and prognostic biomarker in pediatric diseases	14
Annual meeting of the Royal Belgian Society of Laboratory Medicine: “Symphony of the Heart”	14
Is it feasible for European laboratories to use SI units in reporting results?	14
Assessment of the humoral response in Omicron breakthrough cases in healthcare workers who received the BNT162b2 booster	14
In-house diagnostic devices under the EU IVDR and unwanted side-effects of intentional transparency	14
Variations in tumor growth, intra-individual biological variability, and the interpretation of changes	13
Differences between high-sensitivity cardiac troponin T and I in stable populations: underlying causes and clinical implications	13
A randomized controlled study of biochemical tests in primary care: interventions can reduce the number of tests but usage does not become more appropriate	13
Accurate stratification between VEXAS syndrome and differential diagnoses by deep learning analysis of peripheral blood smears	13
Haematology, including haemostasis	13
New concept of interactive academic poster used in medical scientific congress presented in the EuroMedLab 2021 Munich Session	13
Setting analytical performance specifications for copeptin-based testing	13
The first case of Teclistamab interference with serum electrophoresis and immunofixation	13
The biological variation of insulin resistance markers: data from the European Biological Variation Study (EuBIVAS)	13
Understanding the limitations of your assay using EQA data with serum creatinine as an example	13
Kidney diseases	13
Unraveling the mystery of blood groups and COVID-19	13
Precise glucose measurement in sodium fluoride-citrate plasma affects estimates of prevalence in diabetes and prediabetes	13
Limitations of glycated albumin standardization when applied to the assessment of diabetes patients	13
Quality indicators: an evolving target for laboratory medicine	13
Assessing the harmonization of current total vitamin B12 measurement methods: relevance and implications	13
Urine transfer devices may impact urinary particle results: a pre-analytical study	13
Acknowledgment	13
Diagnosis of IRAK-4-deficiency by flow cytometric measurement of IκB-α degradation	13

Evidence-based procedures to improve the reliability of circulating miRNA biomarker assays	12
Clinical implication by differential analytical performances of serum free light chain quantitation analysis using fully automated analyzers	12
Improved implementation of medical tests – barriers and opportunities	12
Rare unstable and low oxygen affinity haemoglobin variant, Hb Hazebrouck, detected on Sysmex XN-9000	12
Transport stability profiling – a proposed generic protocol	12
Inconsistency in ferritin reference intervals across laboratories: a major concern for clinical decision making	12
Clostebol detection after transdermal and transmucosal contact. A systematic review	12
A model for managing quality control for a network of clinical chemistry instruments measuring the same analyte	12
S100B in cardiac surgery brain monitoring: friend or foe?	12
Kinetics and ability of binding antibody and surrogate virus neutralization tests to predict neutralizing antibodies against the SARS-CoV-2 Omicron variant following BNT162b2 booster administration	12
Testosterone analysis in castrated prostate cancer patients: suitability of the castration cut-off and analytical accuracy of the present-day clinical immunoassays	12
Artificial intelligence, clinical decision support and machine learning	12
Tumor markers determination in malignant pleural effusion: pearls and pitfalls	12
The routine coagulation assays plasma stability – in the wake of the new European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) biological variability database	12
An approach for determining allowable between reagent lot variation	12
Nutrition Trace Elements and Vitamins	12
Striving for a pragmatic contribution of biomarkers results to lifelong health care	12
Spike vs. nucleocapsid serum antigens for COVID-19 diagnosis and severity assessment	12
SARS CoV-2 spike protein-guided exosome isolation facilitates detection of potential miRNA biomarkers in COVID-19 infections	12
Estimation of the allowable total error of the absolute CD34+ cell count by flow cytometry using data from UK NEQAS exercises 2004–2024	12
Interferences in immunoassays: review and practical algorithm	11
Laboratory Management, Accreditation, Quality Assurance, performance specification	11
Neurological diseases	11
Sepsis	11
Histamine metabolite to basal serum tryptase ratios in systemic mastocytosis and hereditary alpha tryptasemia using a validated LC-MS/MS approach	11
Novel protocol for metabolomics data normalization and biomarker discovery in human tears	11
A survey on Artificial Intelligence and Big Data utilisation in Italian clinical laboratories	11
Six years of progress – highlights from the IFCC Emerging Technologies Division	11
Preanalytical phase	11
Review and evolution of guidelines for diagnosis of COVID-19 vaccine induced thrombotic thrombocytopenia (VITT)	11
C-terminal alpha-1-antitrypsin peptides as novel predictor of hospital mortality in critically ill COVID-19 patients	11
Frontmatter	11
Arivale is dead ‒ Hooke is alive	11
Comparison between free β subunit of human chorionic gonadotropin (hCG) and total hCG assays in adults with testicular cancer	11
Chemical strategies for sustainable medical laboratories	11
Reference intervals of circulating secretoneurin concentrations determined in a large cohort of community dwellers: the HUNT study	11
Symposium 13 - Prenatal testing	11
Evidence for stability of cardiac troponin T concentrations measured with a high sensitivity TnT test in serum and lithium heparin plasma after six-year storage at −80 °C and multiple freeze-thaw cycl	11
Biological variation of serum Golgi protein 73 concentrations	11
The total testing process harmonization: the case study of SARS-CoV-2 serological tests	11
16ª Reunião Científica da Sociedade Portuguesa de Medicina Laboratorial - SPML	11
M-protein diagnostics in multiple myeloma patients using ultra-sensitive targeted mass spectrometry and an off-the-shelf calibrator	11
Diagnostic accuracy of extended HPV DNA genotyping and its application for risk-based cervical cancer screening strategy	11
Performance evaluation of the introduction of full sample traceability system within the specimen collection process	11
Where is laboratory medicine headed in the next decade? Partnership model for efficient integration and adoption of artificial intelligence into medical laboratories	11
Ct values of different SARS CoV2 variants: a single center observational study from Innsbruck, Austria	11
Diagnostic accuracy of adenosine deaminase for tuberculous pleural effusion: age does matter	11
Correction of negative-interference from calcium dobesilate in the Roche sarcosine oxidase creatinine assay using CuO	10
Traceable machine learning real-time quality control based on patient data	10
Diagnostic performance of Mindray CL1200i high sensitivity cardiac troponin I assay compared to Abbott Alinity cardiac troponin I assay for the diagnosis of type 1 and 2 acute myocardial infarction in	10
Toxicology and TDM	10
An overview of the most important preanalytical factors influencing the clinical performance of SARS-CoV-2 antigen rapid diagnostic tests (Ag-RDTs)	10
Validation of (self-collected) capillary blood using a topper collection system as alternative for venous sampling for 15 common clinical chemistry analytes	10
Immunology	10
The effects of drone transportation on routine laboratory, immunohematology, flow cytometry and molecular analyses	10
Pre-analytical recommendations and reference values for circulating calprotectin are sample type and assay dependent	10
Serum biomarkers of remodeling in severe asthma with fixed airway obstruction and the potential role of KL-6	10
Biological variation of serum iron from the European biological variation study (EuBIVAS)	10
Evaluating the performance of a multiparametric IgA assay for celiac disease diagnosis	10
An appeal for biological variation estimates in deep immunophenotyping	10
Measuring accuracy of the neutralizing activity of COVID-19 convalescent plasma	10
Patient risk management in laboratory medicine: an international survey to assess the severity of harm associated with erroneous reported results	10
First-trimester screening for Down syndrome using quadruple maternal biochemical markers	10
Using artificial intelligence in a primary care setting to identify patients at risk for cancer: a risk prediction model based on routine laboratory tests	10
Searching for the urine osmolality surrogate: an automated machine learning approach	10
Use of high-sensitivity cardiac troponins in the emergency department for the early rule-in and rule-out of acute myocardial infarction without persistent ST-segment elevation (NSTEMI) in Italy	10
Standardization challenges in antipsychotic drug monitoring: insights from a national survey in Chinese TDM practices	9
Impact of different preservation methods on urinary red blood cell counts	9
Positivization time of a COVID-19 rapid antigen self-test predicts SARS-CoV-2 viral load: a proof of concept	9
Analytical and clinical evaluations of Snibe Maglumi® S100B assay	9
Clearance of macro-TSH from the circulation is slower than TSH	9
Impact of ultra-low temperature long-term storage on the preanalytical variability of twenty-one common biochemical analytes	9
Lot-to-lot bias for high-sensitivity cardiac troponin I concentrations ≥1000 ng/L	9
IFCC Symposium - Advancing Excellence in Laboratory Medicine Worldwide: An Update from IFCC Taskforces	9
Is this a true lambda free light chain?	9
The journey to pre-analytical quality	9
Commercial immunoassays for detection of anti-SARS-CoV-2 spike and RBD antibodies: urgent call for validation against new and highly mutated variants	9
Spurious parathyroid hormone (PTH) elevation caused by macro-PTH	9
Association of circulating free and total oxysterols in breast cancer patients	9
Is uracil enough for effective pre-emptive DPD testing?	9
Tutorial: statistical methods for the meta-analysis of diagnostic test accuracy studies	9
Detection of urinary foam cells diagnosing the XGP with thrombopenia preoperatively: a case report	9
Frontmatter	9
Committees	9
Early changes in S100B maternal blood levels can predict fetal intrauterine growth restriction	9
Macroprolactinaemia – some progress but still an ongoing problem	9
Method comparison of three serum free light chain assays on the Roche Cobas 6000 c501 chemistry analyzer	9
Can we identify patients carrying targeted deleterious DPYD variants with plasma uracil and dihydrouracil? A GPCO-RNPGx retrospective analysis	9
External quality assessment of serum indices: Spanish SEQC-ML program	9
The simple reproducibility of a measurement result does not equal its overall measurement uncertainty	9
A novel immunoprecipitation-based targeted liquid chromatography-tandem mass spectrometry analysis for accurate determination for copeptin in human serum	9
Added value of drug-laboratory test interaction alerts in test result authorisation	9
Endocrinology, not including diabetes	9
Analytical performance specifications based on biological variation data – considerations, strengths and limitations	9
Diagnostic utility of pleural cell-free nucleic acids in undiagnosed pleural effusions	8