OOIR: Observatory of International Research

Papers

(The TQCC of Marine Biotechnology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
DNA Methylation Analysis Reveals Potential Mechanism in Takifugu rubripes Against Cryptocaryon irritans Infection	49
Acute Alkaline Stress Activates Glucose Metabolism for Energy Supply and Induces the Immune Response in the Oriental River Prawn, Macrobrachium nipponense	48
Hydin as the Candidate Master Sex Determination Gene in Channel Catfish (Ictalurus punctatus) and Its Epigenetic Regulation	47
Impact of Titanium Dioxide-Graphene Oxide (TiO2-GO) Composite Nanoparticle on the Juveniles of the Giant River Prawn, Macrobrachium rosenbergii: Physio-Biochemistry and Transcriptional Response	43
Sterilization of Channel Catfish (Ictalurus punctatus) via Overexpression of bax Gene Regulated by a Tet-off System in the Primordial Germ Cells	37
Biodegradation of Di-2-Ethylhexyl Phthalate by Mangrove Sediment Microbiome Impacted by Chronic Plastic Waste	28
Tissue and Sex-Specific Transcriptomic Signatures Underlying Aggression behavior of Chinese Mitten Crab (Eriocheir sinensis)	27
High-Temperature-Induced Differential Expression of miRNA Mediates Liver Inflammatory Response in Tsinling Lenok Trout (Brachymystax lenok tsinlingensis)	22
A Novel Beta-Defensin Isoform from Malabar Trevally, Carangoides malabaricus (Bloch & Schneider, 1801), an Arsenal Against Fish Bacterial Pathogens: Molecular Characterization, Recombinant Product	21
Tissue Localization of Tetrodotoxin in the Flatworm Planocera multitentaculata (Platyhelminthes: Polycladida)	21
Genome Analysis of Multiple Polysaccharide-Degrading Bacterium Microbulbifer thermotolerans HB226069: Determination of Alginate Lyase Activity	21
Revealing the Impact of Polystyrene Nanoplastics on Gill Tissues of the Intertidal Clam, Gafrarium Divaricatum (Gmelin, 1791) using Transcriptomics Approach	21
The Effect of High Temperatures on the Growth and Biochemical Composition of Cultivated Palmaria Palmata (Rhodophyta)	21
Targeting TtVgR via siRNA Knockdown Elicits Ovarian Cell Death in the Tri-spine Horseshoe Crab	19
Coral-Derived Antimicrobial Peptides Identified In Silico from Acropora digitifera Transcriptomes: Potential Candidates Against Resistant Pathogens	18
Transcriptomic Profiles of Rainbow Trout (Oncorhynchus mykiss) Selectively Bred for High and Low Fillet Yield	17
Development of a Rapid Detection Method to Prorocentrum lima by Loop-Mediated Isothermal Amplification with Hydroxy Naphthol Blue	17
Biological Functions of Growth Differentiation Factor 9 in Early Ovarian Development of Japanese Eel (Anguilla japonica)	17
Overexpression of Plastid Acetyl-CoA Carboxylase Confers Stress Tolerances with Increased Levels of Unsaturated Fatty Acids in the Marine Diatom Phaeodactylum tricornutum	16
DNA Methylation of Somatic Tissues in Oysters is Influenced by Sex and Heredity	15
The lgi-miR-2d is Potentially Involved in Shell Melanin Synthesis by Targeting mitf in Manila Clam Ruditapes philippinarum	15
Dielectrophoresis for Isolating Low-Abundance Bacteria Obscured by Impurities in Environmental Samples	15
Genomic Selection of Large Yellow Croaker (Larimichthys crocea) with a High Plant Protein Diet Enhances the Growth Performance of Offspring	15
Identification and Genomic Localization of Autosomal sdY Locus in a Population of Atlantic Salmon (Salmo salar)	14
First Report of Screening of Novel Angiotensin-I Converting Enzyme Inhibitory Peptides Derived from the Red Alga Acrochaetium sp.	14

miR-10a-3p Participates in Nacre Formation in the Pearl Oyster Pinctada fucata martensii by Targeting NPY	14
Identification and Functional Characterization of Two Distinct Muscle Stem Cell Populations in Golden Pompano Trachinotus ovatus	14
Transcriptome Analysis of Host Anti-Vibrio harveyi Infection Revealed the Pathogenicity of V. harveyi to American Eel (Anguilla rostrata)	13
Transcriptome Analysis of Different Aquaculture Substrates on the Immune Response of Babylonia areolata	13
Construction of an Enhanced Phage Display Library of Artificially Randomized vNARs from Cloudy Catshark (Scyliorhinus Torazame) and Screening against Miamiensis Avidus	13
The New Roles of traf6 Gene Involved in the Development of Zebrafish Liver and Gonads	13
Genetic Mechanism Analysis Related to Cold Tolerance of Red Swamp Crayfish, Procambarus clarkii	13
Exploring Marine-Derived Polysaccharides Through In Vitro and Zebrafish In Vivo Assays: Initial Trends of A Novel Approach to Drug Screening	13
Gonadal Lipid Storage in Mytilus coruscus: A Comprehensive Gene Network and Key Gene Discovery	13
Structural Variation Analysis in the samd3/elf3 Intergenic Region of the Barred knifejaw (Oplegnathus fasciatus) and the Development of Molecular Marker for Efficient Sex Identification	13
Toll-like Receptor 3 is Required for Sensing Extracellular Double Stranded RNA in Salmonid Cells	13
Transcriptomic Variation of Amphiprion Percula (Lacepède, 1802) in Response to Infection with Cryptocaryon Irritans Brown, 1951	13
Correction to: Environmental Impacts of Large-Scale Spirulina (Arthrospira platensis) Production in Hellisheidi Geothermal Park Iceland: Life Cycle Assessment	12
Versicotide K and Other Secondary Metabolites from the Two Strains of Sponge-Derived Fungi of Aspergillus Genus	12
DOPA Decarboxylase (DDC) in Pacific Oysters: Characterization and Role in Tyrosine Metabolism and Melanogenesis	12
Establishment and Characterization of Novel Channa striata Muscle Cell Line for Scaffold-Based Micro-tissue Production	12
Epigallocatechin-3-gallate Attenuates the Bromo-3-chloro-5,5-dimethylhydantoin-induced Immunotoxicity in Crayfish	12
Molecular Regulation of Biosynthesis of Long Chain Polyunsaturated Fatty Acids in Atlantic Salmon	12
Transcriptomic Responses and Larval-Stage Growth of Protandrous Yellowfin Seabream (Acanthopagrus Latus) to Different Polyethylene Microplastics Exposure	12
Regulatory Genes in Eyespot Formation and Function of Mytilus coruscus	12
The microRNA Targeting Cu/Zn-SOD Increases the Susceptibility To WSSV Under Ammonia Stress in Pacific White Shrimp Litopenaeus vannamei	11
Activin Signaling Pathway Specialization During Embryonic and Skeletal Muscle Development in Rainbow Trout (Oncorhynchus mykiss)	11
Stimulating the Growth of Chlorella Microalgae Using Ultrasound	11
Self-assembling Bioadhesive Inspired by the Fourth Repetitive Sequence of Balanus albicostatus Cement Protein 20 kDa (Balcp-20 k)	11
Comparative Transcriptome Reveals the Potential Modulation Mechanisms of Spdsx Affecting Ovarian Development of Scylla paramamosain	11
siRNA Silencing of FpVtg Induces Ovarian Cell Apoptosis in Redtail Prawn, Fenneropenaeus penicillatus	10
Genomic Structure and Molecular Characterization of Toll-like Receptors in Black Scraper Thamnaconus Modestus and Their Expression Response to Two Types of Pathogens	10
Genome Mining Analysis Uncovers the Previously Unknown Biosynthetic Capacity for Secondary Metabolites in Verrucomicrobia	10
Genetic Basis of Low-Salinity Tolerance in the Pacific Oyster (Crassostrea gigas) as Revealed by Estimation of Genetic Parameters and Genome-Wide Association Study	10
Special Issue-JSMB Marine Biotechnology 2022 Conference	10
Chromosome-Scale Genome Assembly of the Marine Oleaginous Diatom Fistulifera solaris	10
Transcriptome Sequencing Reveals Effects of Artificial Feed Domestication on Intestinal Performance and Gene Expression of Carnivorous Mandarin Fish (Siniperca chuatsi) and Related Mechanisms	10
Delayed First Feeding Chronically Impairs Larval Fish Growth Performance, Hepatic Lipid Metabolism, and Visceral Lipid Deposition at the Mouth-Opening Stage	10
Correction to: Isolation and Identification of High Biomass and Lipid Productivity Euglena Strain from Tropical Malaysian Environments for Enhancement of Biofuel Production	10
A ceRNA Network Mediates Salinity Adaptation Via miR-novel-3-LNC_015168-SLC17A9 Axis in Sea Cucumber	9
Genome-wide Association Study Reveals Novel Growth-related SNPs and Candidate Genes in Grass Carp (Ctenopharyngodon idella) Adapted to Hyper-salinity Stress	9
Tissue-Specific Analysis of Alternative Splicing Events and Differential Isoform Expression in Large Yellow Croaker (Larimichthys crocea) After Cryptocaryon irritans Infection	9
Adaptation of Glucose Metabolism to Limb Autotomy and Regeneration in the Chinese Mitten Crab	9
Electroosmotic Flow-Based Nanoinjection Technique Using a Nanopipette for Green Microalgae	9
Circulating MicroRNAs Indicative of Sex and Stress in the European Seabass (Dicentrarchus labrax): Toward the Identification of New Biomarkers	9
Noninvasive Epidermal Mucus RNA-Seq Analysis for Developing Methods to Evaluate Environmental Stress in the Japanese Eel (Anguilla japonica)	9
Transcriptomic Signature of Lipid Production in Australian Aurantiochytrium sp. TC20	9
Effects of Vitamin C Concentration on the Growth and Development of First Instar Juvenile Chinese Horseshoe Crabs (Tachypleus tridentatus) Determined by Transcriptomic and Enzyme Activity Analyses	9
Environmental Changes Drives the Transcriptome and Gene Regulation Plasticity During Sea Lice Infestation	9
Transcriptome Analysis Revealed the Copper Ion Uptake by Oocystis borgei from Offshore Polluted Water	9
Purification, Identification, and Functional Validation of Anti-Inflammatory Peptides from Protein Hydrolysates of Asian Seabass, Lates Calcarifer by-Product	9
Analysis of In Silico Properties and In Vitro Immunomodulatory Effects of Seven Synthetic Host Defence Peptides in Gilthead Seabream (Sparus aurata) Leucocytes	9
Lipid- and Multivariate-Based Analyses to Determine Cell Response to pH Variations and Buffer Composition	9
Coral Decline Linked to Exchangeable Phosphate in Seawater from Coastal Calcareous Sediments, as Evidenced in Sekisei Lagoon, Japan	9
Genome-wide Identification and Expression Profiling Indicate the Segon Gene Family Diversity and their Possible Role in Shell Formation in Oysters	9

Morpho-histological and Transcriptome Analysis Reveal the Unreduced Sperm Formation Mechanism in cdk1-Depletion Zebrafish	8
Insights into Dietary Different Co-Forms of Lysine and Glutamate on Growth Performance, Muscle Development, Antioxidation and Related Gene Expressions in Juvenile Grass Carp (Ctenopharyngodon idellus)	8
Conjugated Linoleic Acid Reduces Lipid Accumulation via Down-regulation Expression of Lipogenic Genes and Up-regulation of Apoptotic Genes in Grass Carp (Ctenopharyngodon idella) Adipocyte In Vitro	8
Cost-Efficient Production of the Sphingan WL Gum by Sphingomonas sp. WG Using Molasses and Sucrose as the Carbon Sources	8
A Novel Specific Single-Chain Variable Fragment Diagnostic System for Viral Hemorrhagic Septicemia Virus	8
Impact of Probiotics on Enzyme Activities, Intestinal Microbial Remodeling, and Metabolic Pathways in American Shad (Alosa sapidissima) at High Temperatures	8
Long-Read Sequencing Revealing the Effectiveness of Captive Breeding Strategy for Improving the Gut Microbiota of Spotted Seal (Phoca largha)	8
Enhancement of Squalene Production by Constitutive Expression of the 3-Hydroxy-3-Methylglutaryl-CoA Reductase in Aurantiochytrium sp. 18W-13a	8
Development of DNA Insertion-specific Markers Based on the Intron Region of Oplegnathus punctatus itih4b for Genetic Sex Identification	8
Production of Antioxidant, Angiotensin-Converting Enzyme Inhibitory and Osteogenic Gelatin Hydrolysate from Labeo rohita Swim Bladder	8
Discovery of Natural Hybridization and Development of an Efficient Identification Marker Between Coilia Nasus and Coilia Brachygnathus	8
Integrated Transcriptomic Analysis Uncovers the Protective Effects of Berberine Hydrochloride in Enhancing Hepatic Caecum Response of Branchiostoma belcheri (Chinese lancelet) to Aeromonas hydrophila	8
A Novel CaCO3/LPE/CA for Breeding Pyropia Haitanensis Artificial Shell-Boring Conchocelis	8
Anti-inflammatory Effects of the Fucoidan from Sea Cucumber Apostichopus japonicus	7
Differentiation and Maturation of Muscle and Fat Cells in Cultivated Seafood: Lessons from Developmental Biology	7
MiR-382 Functions on the Regulation of Melanogenesis via Targeting dct in Rainbow Trout (Oncorhynchus mykiss)	7
Publisher Correction: Flow Velocity Modulates Growth, Oxidative Stress, and Transcriptomic Responses in Spotted Sea Bass (Lateolabrax maculatus)	7
Integrated Analysis of mRNA-seq and miRNA-seq Reveal the Dynamics of the Gonadal Differentiation of Procypris Mera	7
Flow Velocity Modulates Growth, Oxidative Stress, and Transcriptomic Responses in Spotted Sea Bass (Lateolabrax maculatus)	7
A Comparison of the Biotechnological Potential of Marine and Terrestrial Species of Two Orders of Sordariomycete Fungi	7
Natural Products from Soft Corals in Taiwan: Insights into Chemical Taxonomy and Potential Interaction in Marine Environments	7
Recent Advances of Marine Sponge-Associated Microorganisms as a Source of Commercially Viable Natural Products	7
Effects of Light Intensity on Growth Performance and Physiological Responses in Juvenile Mandarin Fish (Siniperca chuatsi)	7
Dietary Leucine Requirement and Its Effects on Growth, Immunity, Antioxidant Capacity and Protein Metabolism in Pacific White Shrimp, Penaeus vannamei	7
Genome-Wide Identification of Long Non-coding RNAs in Crassostrea gigas and Their Association with Heat Stress	7
A New Investigation to Discriminate Sexes in Alive Nile Tilapia (Oreochromis niloticus) Using Cyp19a1a and Dmrt1 Gene Expression in Tail Fin Tissues	7
Comparisons of Methods for Mucus Sampling and Mucin Semi-Quantification on Barramundi (Lates calcarifer) and Atlantic Salmon (Salmo salar) Epithelial Sites	7
Effects of Microplastics on Gene Expression, Muscular Performance, and Immunological Responses in Nile Tilapia (Oreochromis niloticus): Seasonal and Habitat Variations	7
Mass Spectrometry Metabolomics Approach Reveals Anti-Trichomonas vaginalis Scaffolds from Marine Fungi	7
Comparative Methylome Analysis Reveals Epigenetic Signatures Associated with Growth and Shell Color in the Pacific Oyster, Crassostrea gigas	6
A Novel Thermo-Alkaline Stable GDSL/SGNH Esterase with Broad Substrate Specificity from a Deep-Sea Pseudomonas sp.	6
Transcriptome Analysis of Genes Responsive to Nutrient Level Changes in the Marine Red Alga Pyropia yezoensis (Nori)	6
Correction to: HcN13, a Fibroblast Growth Factor Binding Protein, Is Associated with Shell Formation in Hyriopsis cumingii	6
Mutations Upstream of ppp2ca Affect Body Weight in Asian Seabass	6
RNA-seq Provides Novel Insights into Response to Acute Salinity Stress in Oriental River Prawn Macrobrachium nipponense	6
Integrative Assessment of Interrelated Swimming Performances and their Physiological Basis in Large Yellow Croaker (Larimichthys crocea)	6
Environmental Exosomes/Small Extracellular Vesicles: Evidence of Extracellular RNA Release by Aquatic Organisms	6
Silencing Asian Seabass gab3 Inhibits Nervous Necrosis Virus Replication	6
Nuclear DNA Content Variation in Different Life Cycle Stages of Sugar Kelp, Saccharina latissima	6
Vitamin B12 is Essential for Growth, Innate Immunity, Antioxidant Capacity, Fatty Acid and Amino Acid Metabolism, and Ammonia Tolerance in Pacific White Shrimp, Penaeus vannamei	6
Marine Bioceramic Generation for Bone Tissue Regeneration: Sea Urchin (Echinometra mathaei) Exoskeleton-Derived Calcium Carbonate as a Precursor for Hydroxyapatite Synthesis, Incorporated into Chitosa	6
Breeding of New Strains of Gracilariopsis lemaneiformis with High Agar Content by ARTP Mutagenesis and High Osmotic Pressure Screening	6
The Landscape of Liver Chromatin Accessibility and Conserved Non-coding Elements in Larimichthys crocea, Nibea albiflora, and Lateolabrax maculatus	6
Correction: The Effect of Co-Culture of Two Coral Species on Their Bacterial Composition Under Captive Environments	6
A Novel Investigation for Early Sex Determination in Alive Adult European Seabass (Dicentrarchus labrax) Using cyp19a1a, dmrt1a, and dmrt1b Genes Expression in Tail Fin tissues	6
SNP Fingerprinting for Germplasm Identification of the Fast-Growing Pacific oyster (Crassostrea gigas) “Haida No. 1” Variety	6
Aquafeed Enrichment with Dictyota Dichotoma and Bacillus Coagulans: A Synergistic Strategy to Promote Growth, Immune Function, and Antioxidant Defensive Pathways in Cyprinus Carpio	6
Improved Protective Efficacy in Rainbow Trout (Oncorhynchus mykiss) Against Vibrio anguillarum Through Immunization with a Combination of Formalin-Killed and Auxotrophic-Live V. anguillarum	5
Physiological Responses to Acute Heat Stress in Rohu, Labeo rohita: Insights from Liver Proteomics	5
Lipid Droplet Degradation Through Lipophagy in Aurantiochytrium limacinum mh0186	5
Comparative Transcriptome Analysis Reveals the Light Spectra Affect the Growth and Molting of Scylla paramamosain by Changing the Chitin Metabolism	5
First Genomic Prediction of Single-Step Models in Large Yellow Croaker	5
Comparison of Muscle Color and Total Selenium Concentrations Between Spotted Mackerel Scomber australasicus and Pacific Mackerel S. japonicus	5
Different Responses of Photosynthesis to Nitrogen Starvation Between Highly Oil-Accumulative Diatoms, Fistulifera solaris and Mayamaea sp. JPCC CTDA0820	5
Physiological and Metabolic Responses to Graded Dietary Biotin Supplementation in Juvenile Penaeus vannamei	5
Temporal Transcriptomic Profiling Reveals Dynamic Changes in Gene Expression of Giant Freshwater Prawn upon Acute Saline-Alkaline Stresses	5
Transcriptome Analysis Reveals the lncRNA-mRNA Co-expression Network Regulating the Aestivation of Sea Cucumber	5
Mechanically Enhanced Salmo salar Gelatin by Enzymatic Cross-linking: Premise of a Bioinspired Material for Food Packaging, Cosmetics, and Biomedical Applications	5
An Improved RNA Extraction Method for Octocorals and Its Application in Transcriptome Analysis of Dark-Induced Bleaching Octocoral	5
Comparative Transcriptome Analysis of Head Kidney of Aeromonas hydrophila-infected Hypoxia-tolerant and Normal Large Yellow Croaker	5
Utilization of Marine Seaweeds as a Promising Defense Against COVID-19: a Mini-review	5
Cold Stress Induces Apoptosis in Silver Pomfret via DUSP-JNK Pathway	5
Reproductive Benefits of Dietary Selenium Nanoparticles (SeNPs) in Asian Seabass (Lates calcarifer) Male Broodstock	5
Postbiotic Dietary Supplementation with Sonicated Shewanella sp. SpPdp11 Improves Intestinal Status in Juvenile Senegalese Sole (Solea senegalensis)	5
Comparative Transcriptome Analysis Reveals the Role of Ribosome Reduction in Impeding Oogenesis in Female Triploid Crassostrea Gigas	5
HcN13, a Fibroblast Growth Factor Binding Protein, Is Associated with Shell Formation in Hyriopsis cumingii	5
Study of Molecular Docking and Evolutionary Dynamics of the FGF Gene Family in Nile Tilapia	5
Transcriptomic Response of the Atlantic Surfclam (Spisula solidissima) to Acute Heat Stress	5
Bacteria-Produced Algicide for Field Control of Toxic Dinoflagellates Does Not Cause a Cortisol Stress Response in Two Estuarine Fish Species	5
Identification of a Novel QTL on LG16 Associated with Acute Salt Tolerance in Red Tilapia (Oreochromis spp.) Using GWAS	5
Epigenetic Regulation Links Bacterial Signaling to Growth and Reproductive Development in the Green Macroalga Ulva compressa (Chlorophyta)	5
Onnamides and a Novel Analogue, Onnamide G, as Potent Leishmanicidal Agents	5
Extraction and Purification of Biopolymers from Marine Origin Sources Envisaging Their Use for Biotechnological Applications	5
Vanadium Accumulation and Reduction by Vanadium-Accumulating Bacteria Isolated from the Intestinal Contents of Ciona robusta	5