OOIR: Observatory of International Research

Papers

(The TQCC of Pharmacogenomics is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Identification of RNA Modification-Associated Single-Nucleotide Polymorphisms in Genomic Loci for Low-Density Lipoprotein Cholesterol Concentrations	37
miR-369-3p regulates the drug resistance of lung cancer cells by targeting PTPN12	27
Pharmacogenomics in Psychiatry – the Challenge of Cytochrome P450 Enzyme Phenoconversion and Solutions to Assist Precision Dosing	26
Assessing patient understanding of pharmacogenomic test results: a qualitative study	24
How to implement pre-emptive pharmacogenetic testing in the acute hospital setting	23
Pharmacogenomic variants affecting efficacy and safety of medicines acting on central nervous system among Sri Lankans	22
Evidence level for pharmacogenetic testing in antidepressant treatment: a systematic review	19
Patient comprehension of preemptive pharmacogenomic results	17
Pharmacogenomics for Prader-Willi syndrome: caregiver interest and planned utilization	16
Genetics and response to treatment with metformin for type 2 diabetes	15
Pharmacogenetics of Sulfonylurea-Induced Hypoglycemia in Type 2 Diabetes Patients: the SUCLINGEN Study	13
Rapid point of care testing: the next frontier in pharmacogenomics	12
Assessing the Utility of Measurement Methods Applied in Economic Evaluations of Pharmacogenomics Applications	12
Severe systemic Adverse Reactions to Ophthalmic Timolol in a CYP2D6 Homozygous *4 Allele Carrier: A Case Report	12
CYP2D6 genotyping in a Korean cohort: comparative analysis with Asian, Caucasian, and African populations	11
A systematic review of single nucleotide polymorphisms affecting allopurinol pharmacokinetics and serum uric acid level	11
Integrated in a Systems Pharmacology Approach, Pharmacogenetics holds the Promise for Personalized Medicine in Neonates	11
Characterization of CYP2C19 Pharmacogenetic Variation in African Populations and Comparison with Other Global Populations	11
CYP2D6 Gene Resequencing in the Malagasy, a Population at the Crossroads between Asia and Africa: A Pilot Study	10
Gene Polymorphisms Affect Postoperative Imatinib Plasma Levels and Edema in Adults With Gastrointestinal Stromal Tumor	10
Contrasting ABCB1 Pharmacogenetics and Psychotropic Responses in Child and Adolescent Psychiatry: A case comparison	10
Association of NAT-2 Gene Polymorphisms Toward Lung Cancer Susceptibility and Prognosis in North Indian Patients Treated with Platinum-Based Chemotherapy	9
Multiple Genetic Mutations Increase the Risk of Thrombosis Associated With Clopidogrel After Percutaneous Coronary Intervention	9
A Survey of Physician Opinions in Russia in the Field of Pharmacogenetics of Cardiovascular Disease	9
Cost–Effectiveness of HLA-B58:01* Testing to Prevent Stevens–Johnson Syndrome/Toxic Epidermal Necrolysis in Vietnam	8

Improving the Management of ALK-Rearranged Non-Small-Cell Lung Cancer Through a Mobile Application: A Physicians-Based Survey	8
Workforce readiness for pharmacogenomics and key elements for sustainment within the Veterans Health Administration	8
Genetic polymorphisms and adverse reactions to antituberculosis therapy	8
EFfects of UGT1A , CYP2C9/19 and ABAT Polymorphisms on Plasma Concentration of Valproic Acid in Chinese Epi	8
Pharmacogenetic markers and macrolide safety in influenza patients: insights from a prospective study	8
The Promise�of Digital Health in Healthcare Equity and Medication Adherence in the Disadvantaged Dementia Population	8
Genetika+: Precision Medicine Solutions for Mental Health	7
Impact of genetic variants on fentanyl metabolism in major breast surgery patients: a candidate gene association study	7
Pharmacogenomics and rare diseases: optimizing drug development and personalized therapeutics	7
A critical review of RAF inhibitors in BRAF-mutated glioma treatment	7
The cost–effectiveness of zolbetuximab in CLDN18.2-positive gastric or gastroesophageal junction adenocarcinoma	7
Head-to-head Comparison of Various Antipsychotic Agents on Genome-Wide Methylation in Schizophrenia	7
Genetic Factors Associated with Tuberculosis-Related Clinical Outcomes in HIV-Infected Black African Patients: a Systematic Review and Meta-Analysis	7
UGT1A1 Genotype-Guided Dosing of Irinotecan: Time to Prioritize Patient Safety	7
Effects of CYP3A4 and CYP2C9 Genotype on Systemic Anastrozole and Fulvestrant Concentrations in SWOG S0226	6
Pharmacogenomic implications of the differential distribution of CYP3A5 metabolic phenotypes among Latin American populations	6
DDX11-AS1 Modulates Dna Damage Repair to Enhance Paclitaxel Resistance of Lung Adenocarcinoma Cells	6
TPMT and NUDT15 genotyping, TPMT enzyme activity and metabolite determination for thiopurines therapy: a reference laboratory experience	6
SLCO1B1 and ABCB1 Variants Synergistically Influence the Atorvastatin Treatment Response in South Indian Coronary Artery Disease Patients	6
The Festival of Genetics and Personalized Medicine	6
Accuracy and technical characteristics of CYP2C19 point of care tests: a systematic review	6
Barriers and facilitators for implementing a pharmacogenetic passport: lessons learned from reusing sequencing data	6
DPYD Genotyping and Predicting Fluoropyrimidine Toxicity: Where do we Stand?	5
Pharmacogenomics: A Tool to Improve Medication Safety and Efficacy in Patients with Cystic Fibrosis	5
Predicting laboratory aspirin resistance in Chinese stroke patients using machine learning models by GP1BA polymorphism	5
Genetic risk factors for drug-induced long QT syndrome: findings from a large real-world case–control study	5
Polymorphisms of Genes Related to Phase II Metabolism and Resistance to Clopidogrel	5
XDH Genotypes Through Gene–Gene Interactions with NUDT15 Affect Azathioprine-Induced Leukopenia in Chinese Patients	5
Patient Satisfaction With Return of Pharmacogenomic Results Utilizing a Patient Portal Message	5
Posttransplantation diabetes mellitus (PTDM): pharmacological aspects and genetic predispositions	5
Donor-Derived Cell Free DNA as a Biomarker in Kidney Transplantation	5
Estimated clinical utility of multi-gene pharmacogenetic testing in a retrospective cohort of gynecology patients	5
Glutathione S -transferase Gene Polymorphism and Asthma: A Case–Control Study in a Pediatric Population	5
Erratum	5
Exploring the Potential Benefits of Pharmacogenomics in Chronic Respiratory Diseases	5
The Genetics of Drug-Induced Qt Prolongation: Evaluating the Evidence for Pharmacodynamic Variants	5
Pharmacogenomics in Pediatric Medicine and Drug Development	5
Association between CYP3A4 , CYP3A5 and ABCB1 Genotype and Tacrolimus Treatment Outcomes Among Allogeneic H	5
Carbamazepine Cutaneous Adverse Reactions and HLA Gene Variation in the Chinese Population: A Systematic Review and Meta-Analysis	5
Knowledge and Attitudes of Incoming Pharmacy Students Toward Pharmacogenomics and Survey Reliability	5
Genetic polymorphisms of OPRM1 on the Efficacy and Safety of Anesthetic and Analgesic Agents: A Systematic Review	5
The Frequency Of Rs2231142 in ABCG2 Among Native Hawaiian nd Pacific Islander Subgroups: Implications for Personalized Rosuvastatin Dosing	4
Bioinformatic Tools are Essential to Integrating Pharmacogenomics into Clinical Practice: Lessons from Neuropsychiatric Disorders	4
Liquid biopsy: an essential tool for metastatic breast cancer’s follow-up	4
KCNQ1 Variant rs163184 is a Potential Biomarker of Glycemic Response to Exenatide	4
Single-Nucleotide Polymorphisms in ABC Drug Transporters Alter Expression and Circulating Tenofovir in Healthy South African Women Exposed to Pre-Exposure Prophylaxis	4
Clinical Pharmacology and Pharmacogenomics for Implementation of Personalized Medicine	4
Pharmacogenetics of HIV Therapy: Challenges for Tailoring Treatment in Genetically Complex Populations	4
Pharmacogenomic Study of Anthracycline-Induced Cardiotoxicity in Mexican Pediatric Patients	4
Relevance of NAT2 Genotype and Clinical Factors to Risk for Antituberculosis Drug-Induced Liver Injury	4

Overview of the Year 2023 at Pharmacogenomics	4
Impact of CYP2C19 Gene Polymorphisms on Warfarin Dose Requirement: A Systematic Review and Meta-Analysis	4
The Revolution of Pharmaco-Omics: Ready to Open new Avenues in Materializing Precision Medicine?	4
The Importance of Phenoconversion when using the CYP2D6 Genotype in Clinical Practice	4
Variation in the ABC transporter genes and association with clinical outcomes in colorectal cancer: a brief review	4
Dosage Optimization of Clopidogrel Via a Precision Medicine Approach: The Way Forward	4
Influence of CYP3A5 , IL-10 Polymorphisms and Metabolism Rate on Tacrolimus Exposure in Renal Post-Transplant Recipients	4
Pharmacogenomic curriculum in Australian medical schools: a content analysis study	4
Relevance of NR1I2 Variants on Carbamazepine Therapy in Mexican Mestizos with Epilepsy at a Tertiary-Care Hospital	4
Impact of ABCB1 gene polymorphism on clopidogrel plasma concentration and cardiovascular events in post-PCI patients	4
Pharmacogenomic Prescribing Opportunities in Percutaneous Coronary Intervention and Bone Marrow Transplant Patients	4
Pharmacogenetics of Calcineurin inhibitors in kidney transplant recipients: the African gap. A narrative review	4