OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 70. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)

Article	Citations
STING and fat crosstalk	687
TRIM8 in Ewing sarcoma	460
Force boosts SARS-CoV-2 invasion	369
Enhancing T cell therapy	280
Pushing chromatin to totipotency	227
Restoring placental methylome	224
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	200
Criteria for the standardization of stem-cell-based embryo models	191
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	175
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	171
The guinea pig serves as an alternative model to study human preimplantation development	157
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	157
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	144
tRNA flux and consistency in differentiation	139
Keeping membraneless organelles apart	139
An inflammatory switch for stem cell plasticity	135
COPIng with senescence	134
Finding a chaperone for TDP-43	131
RIPK1 and RIPK3 form mosaic necrosomes	126
ER-associated RNA silencing promotes ER quality control	124
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	121
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	120
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	119
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	118
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	116

A guideline on the molecular ecosystem regulating ferroptosis	115
Telomere dysfunction in ageing and age-related diseases	114
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	112
A serendipitous discovery of a family of membrane remodelling proteins	112
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	111
Regenerating the academic pipeline	107
PRC2 shields the potency of human stem cells	104
How a ribosomal protein avoids mixed signals	104
Publisher Correction: p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth	104
HSF1 renders NK cells too stressed to respond	104
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	102
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	101
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	100
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	100
Nuclear class 3 PI3K coactivates circadian clock	98
Membranes regulate biomolecular condensates	97
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	96
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	96
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	94
Real-time and programmable transcriptome sequencing with PROFIT-seq	91
Implementing sustainable science in the lab	90
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	89
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	88
A lysosomal surveillance response to stress extends healthspan	87
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	86
Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elements	86
Spermidine is essential for fasting-mediated autophagy and longevity	83
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	83
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	83
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	83
A cell biological perspective on Singapore’s scientific growth	82
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	82
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	81
Deep-learning for microscopy	81
Xist seeds X inactivation	81
Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells	79
Time for lipid cell biology	79
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	77
It started with a western	74
Telomeres are a life-extending gift	74
Waste management and cell death in T cells	72
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	72
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	71
Tissue memory relies on stem cell priming in distal undamaged areas	71
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	70
Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning	70
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	70