OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
STING and fat crosstalk	738
TRIM8 in Ewing sarcoma	508
Force boosts SARS-CoV-2 invasion	398
Enhancing T cell therapy	294
Pushing chromatin to totipotency	236
Restoring placental methylome	217
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	204
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	187
Keeping membraneless organelles apart	186
tRNA flux and consistency in differentiation	168
COPIng with senescence	167
Finding a chaperone for TDP-43	162
An inflammatory switch for stem cell plasticity	159
The guinea pig serves as an alternative model to study human preimplantation development	153
Atlas of amnion development during the first trimester of human pregnancy	147
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	144
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	143
RIPK1 and RIPK3 form mosaic necrosomes	136
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	134
Criteria for the standardization of stem-cell-based embryo models	133
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	132
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	131
Telomere dysfunction in ageing and age-related diseases	129
ER-associated RNA silencing promotes ER quality control	127
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	127

ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	127
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	123
A guideline on the molecular ecosystem regulating ferroptosis	123
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	121
A serendipitous discovery of a family of membrane remodelling proteins	119
Regenerating the academic pipeline	118
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	118
How a ribosomal protein avoids mixed signals	116
Real-time and programmable transcriptome sequencing with PROFIT-seq	112
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	112
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	107
HSF1 renders NK cells too stressed to respond	106
PRC2 shields the potency of human stem cells	106
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	106
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	105
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	103
Nuclear class 3 PI3K coactivates circadian clock	102
A lysosomal surveillance response to stress extends healthspan	102
Membranes regulate biomolecular condensates	100
Implementing sustainable science in the lab	99
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	98
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	96
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	95
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	95
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	93
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis	91
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	91
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	91
Spermidine is essential for fasting-mediated autophagy and longevity	90
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	88
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	87
A cell biological perspective on Singapore’s scientific growth	87
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	87
Xist seeds X inactivation	83
Deep-learning for microscopy	83
Telomeres are a life-extending gift	82
It started with a western	80
Waste management and cell death in T cells	80
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	79
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	77
A model for propagation of RNA structural memory through biomolecular condensates	76
Time for lipid cell biology	76
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	75
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	75
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells	74
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	73
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	73