OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 73. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Pushing chromatin to totipotency	798
STING and fat crosstalk	548
Enhancing T cell therapy	422
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	314
Keeping membraneless organelles apart	243
tRNA flux and consistency in differentiation	240
COPIng with senescence	214
Restoring placental methylome	204
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	199
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	195
Atlas of amnion development during the first trimester of human pregnancy	184
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	171
Finding a chaperone for TDP-43	164
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	163
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	157
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	157
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	155
The guinea pig serves as an alternative model to study human preimplantation development	152
RIPK1 and RIPK3 form mosaic necrosomes	150
ER-associated RNA silencing promotes ER quality control	149
A guideline on the molecular ecosystem regulating ferroptosis	144
Criteria for the standardization of stem-cell-based embryo models	143
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	143
Telomere dysfunction in ageing and age-related diseases	142
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	140

How a ribosomal protein avoids mixed signals	139
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	139
Regenerating the academic pipeline	137
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	134
A serendipitous discovery of a family of membrane remodelling proteins	129
Nuclear class 3 PI3K coactivates circadian clock	127
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis	127
Implementing sustainable science in the lab	126
PRC2 shields the potency of human stem cells	121
HSF1 renders NK cells too stressed to respond	116
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	115
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	113
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	112
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	110
A lysosomal surveillance response to stress extends healthspan	110
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death	109
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	108
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	106
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	106
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	105
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	105
Real-time and programmable transcriptome sequencing with PROFIT-seq	104
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	104
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	103
Spermidine is essential for fasting-mediated autophagy and longevity	99
Membranes regulate biomolecular condensates	97
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	97
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	94
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	93
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	93
Deep-learning for microscopy	91
A cell biological perspective on Singapore’s scientific growth	90
Xist seeds X inactivation	88
Telomeres are a life-extending gift	87
Waste management and cell death in T cells	86
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	84
A model for propagation of RNA structural memory through biomolecular condensates	84
It started with a western	83
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	82
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	81
p16-dependent increase of PD-L1 stability regulates immunosurveillance of senescent cells	80
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	79
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	78
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	76
Label-free multiplexed microtomography of endogenous subcellular dynamics using generalizable deep learning	75
Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells	74
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	73
Time for lipid cell biology	73