OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 72. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Pushing chromatin to totipotency	763
STING and fat crosstalk	533
Enhancing T cell therapy	414
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	302
Keeping membraneless organelles apart	239
tRNA flux and consistency in differentiation	230
COPIng with senescence	207
Restoring placental methylome	191
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	190
Atlas of amnion development during the first trimester of human pregnancy	183
Force boosts SARS-CoV-2 invasion	174
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	166
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	164
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	161
The guinea pig serves as an alternative model to study human preimplantation development	152
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	152
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	148
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	142
ER-associated RNA silencing promotes ER quality control	141
RIPK1 and RIPK3 form mosaic necrosomes	139
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	137
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	136
Finding a chaperone for TDP-43	136
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	134
Telomere dysfunction in ageing and age-related diseases	133

A guideline on the molecular ecosystem regulating ferroptosis	133
Criteria for the standardization of stem-cell-based embryo models	130
Regenerating the academic pipeline	129
How a ribosomal protein avoids mixed signals	129
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	126
A serendipitous discovery of a family of membrane remodelling proteins	122
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	120
Nuclear class 3 PI3K coactivates circadian clock	118
Membranes regulate biomolecular condensates	114
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis	113
Implementing sustainable science in the lab	112
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	109
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	109
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	108
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	107
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	104
Real-time and programmable transcriptome sequencing with PROFIT-seq	104
HSF1 renders NK cells too stressed to respond	103
PRC2 shields the potency of human stem cells	103
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	102
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	102
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	99
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	98
A lysosomal surveillance response to stress extends healthspan	98
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	95
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	92
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	91
Spermidine is essential for fasting-mediated autophagy and longevity	91
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	90
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	90
Deep-learning for microscopy	89
A cell biological perspective on Singapore’s scientific growth	88
Xist seeds X inactivation	85
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	85
Sequential enhancer state remodelling defines human germline competence and specification	84
Telomeres are a life-extending gift	83
Waste management and cell death in T cells	81
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	81
It started with a western	81
Time for lipid cell biology	80
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	78
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	77
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	77
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	76
Tissue memory relies on stem cell priming in distal undamaged areas	74
A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling	73
Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells	73