OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 73. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Pushing chromatin to totipotency	847
STING and fat crosstalk	575
Enhancing T cell therapy	447
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	260
Keeping membraneless organelles apart	255
tRNA flux and consistency in differentiation	245
COPIng with senescence	213
Restoring placental methylome	202
Atlas of amnion development during the first trimester of human pregnancy	201
Finding a chaperone for TDP-43	186
ER-associated RNA silencing promotes ER quality control	181
Designing protein-based artificial kinetochores as decoys to prevent meiotic errors in oocytes	172
The guinea pig serves as an alternative model to study human preimplantation development	170
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	164
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	163
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	161
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	158
RIPK1 and RIPK3 form mosaic necrosomes	155
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	153
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	153
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	149
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	149
Criteria for the standardization of stem-cell-based embryo models	147
Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	145
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	144

A guideline on the molecular ecosystem regulating ferroptosis	137
Telomere dysfunction in ageing and age-related diseases	137
Regenerating the academic pipeline	136
How a ribosomal protein avoids mixed signals	136
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	135
A serendipitous discovery of a family of membrane remodelling proteins	130
Nuclear class 3 PI3K coactivates circadian clock	123
Implementing sustainable science in the lab	122
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	121
Real-time and programmable transcriptome sequencing with PROFIT-seq	121
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	119
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	118
A lysosomal surveillance response to stress extends healthspan	117
PRC2 shields the potency of human stem cells	114
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	113
HSF1 renders NK cells too stressed to respond	113
Synthetic ZFTA fusions pinpoint disordered protein domain acquisition as a mechanism of brain tumorigenesis	112
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	107
MAPL regulates gasdermin-mediated release of mtDNA from lysosomes to drive pyroptotic cell death	104
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	103
Membranes regulate biomolecular condensates	101
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	100
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	100
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	98
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	97
Spermidine is essential for fasting-mediated autophagy and longevity	95
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	91
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	91
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	91
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	91
A cell biological perspective on Singapore’s scientific growth	90
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	90
Telomeres are a life-extending gift	89
Waste management and cell death in T cells	88
It started with a western	87
Sequential enhancer state remodelling defines human germline competence and specification	85
Assessing gene loss after gene editing	85
A model for propagation of RNA structural memory through biomolecular condensates	85
Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells	83
Deep-learning for microscopy	83
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	82
Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system	82
p300 nucleocytoplasmic shuttling underlies mTORC1 hyperactivation in Hutchinson–Gilford progeria syndrome	80
Escape from X inactivation is directly modulated by Xist noncoding RNA	79
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	77
A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling	76
N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition	75
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	74