OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 70. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
STING and fat crosstalk	719
TRIM8 in Ewing sarcoma	481
Force boosts SARS-CoV-2 invasion	390
Enhancing T cell therapy	289
Pushing chromatin to totipotency	228
Restoring placental methylome	212
Dynamic regulation of integrin β1 phosphorylation supports invasion of breast cancer cells	195
ATFS-1 counteracts mitochondrial DNA damage by promoting repair over transcription	181
Unravelling the endoplasmic reticulum–Golgi intermediate compartment in plant cells	180
Keeping membraneless organelles apart	164
tRNA flux and consistency in differentiation	160
COPIng with senescence	150
Finding a chaperone for TDP-43	148
RIPK1 and RIPK3 form mosaic necrosomes	144
Compression-dependent microtubule reinforcement enables cells to navigate confined environments	142
Human induced pluripotent stem cell-derived salivary gland organoids model SARS-CoV-2 infection and replication	140
Criteria for the standardization of stem-cell-based embryo models	137
ER-associated RNA silencing promotes ER quality control	133
Atlas of amnion development during the first trimester of human pregnancy	129
ETV2 functions as a pioneer factor to regulate and reprogram the endothelial lineage	127
An inflammatory switch for stem cell plasticity	126
The guinea pig serves as an alternative model to study human preimplantation development	123
Spatial and functional separation of mTORC1 signalling in response to different amino acid sources	123
Telomere dysfunction in ageing and age-related diseases	122
A guideline on the molecular ecosystem regulating ferroptosis	120

Cysteine oxidation of copper transporter CTR1 drives VEGFR2 signalling and angiogenesis	120
Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture	119
Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function	116
A serendipitous discovery of a family of membrane remodelling proteins	115
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβ	115
Metabolic regulation of chemoresistance and immuno-surveillance in AML by SHP-1	112
Regenerating the academic pipeline	111
How a ribosomal protein avoids mixed signals	110
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK–STAT endosomal activation	107
PRC2 shields the potency of human stem cells	105
HSF1 renders NK cells too stressed to respond	105
Nuclear class 3 PI3K coactivates circadian clock	104
TCF3, TCF12 and distinct enhancers regulate oocyte transcription	104
Membranes regulate biomolecular condensates	104
Implementing sustainable science in the lab	100
Real-time and programmable transcriptome sequencing with PROFIT-seq	99
A lysosomal surveillance response to stress extends healthspan	98
Diverse heterochromatin-associated proteins repress distinct classes of genes and repetitive elements	98
The nuclear periphery confers repression on H3K9me2-marked genes and transposons to shape cell fate	94
Host extracellular vesicles confer cytosolic access to systemic LPS licensing non-canonical inflammasome sensing and pyroptosis	94
Nuclear proteasomes buffer cytoplasmic proteins during autophagy compromise	94
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	91
The MARCHF6 E3 ubiquitin ligase acts as an NADPH sensor for the regulation of ferroptosis	90
Dapl1 controls NFATc2 activation to regulate CD8+ T cell exhaustion and responses in chronic infection and cancer	89
VAMP2 chaperones α-synuclein in synaptic vesicle co-condensates	88
The Polycomb system sustains promoters in a deep OFF state by limiting pre-initiation complex formation to counteract transcription	88
Hyaluronic acid–GPRC5C signalling promotes dormancy in haematopoietic stem cells	88
Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification	87
Lymphotoxin-β promotes breast cancer bone metastasis colonization and osteolytic outgrowth	87
Spermidine is essential for fasting-mediated autophagy and longevity	86
IL-2 delivery by engineered mesenchymal stem cells re-invigorates CD8+ T cells to overcome immunotherapy resistance in cancer	85
A cell biological perspective on Singapore’s scientific growth	83
Ras suppression potentiates rear actomyosin contractility-driven cell polarization and migration	83
Xist seeds X inactivation	82
Deep-learning for microscopy	82
Telomeres are a life-extending gift	79
It started with a western	78
ETV4 is a mechanical transducer linking cell crowding dynamics to lineage specification	77
Waste management and cell death in T cells	77
Identification of a retinoic acid-dependent haemogenic endothelial progenitor from human pluripotent stem cells	75
Sequential enhancer state remodelling defines human germline competence and specification	74
Intron-encoded cistronic transcripts for minimally invasive monitoring of coding and non-coding RNAs	73
Atypical nuclear envelope condensates linked to neurological disorders reveal nucleoporin-directed chaperone activities	72
Time for lipid cell biology	72
Malonyl-CoA is a conserved endogenous ATP-competitive mTORC1 inhibitor	72
Fructose-1,6-bisphosphatase 1 functions as a protein phosphatase to dephosphorylate histone H3 and suppresses PPARα-regulated gene transcription and tumour growth	70