OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Cell Biology is 70. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis	506
Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis	302
Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis	291
Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture	239
SIRT1 is downregulated by autophagy in senescence and ageing	231
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker	221
Telomere dysfunction in ageing and age-related diseases	219
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression	214
Cell–cell adhesion and 3D matrix confinement determine jamming transitions in breast cancer invasion	208
PKCβII phosphorylates ACSL4 to amplify lipid peroxidation to induce ferroptosis	204
CRISPR technologies for precise epigenome editing	204
Circular RNA-encoded oncogenic E-cadherin variant promotes glioblastoma tumorigenicity through activation of EGFR–STAT3 signalling	187
Nucleated transcriptional condensates amplify gene expression	187
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy	183
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets	181
Targeting liquid–liquid phase separation of SARS-CoV-2 nucleocapsid protein promotes innate antiviral immunity by elevating MAVS activity	161
Robust gene expression programs underlie recurrent cell states and phenotype switching in melanoma	155
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis	151
Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin	149
ERBB2 drives YAP activation and EMT-like processes during cardiac regeneration	128
Cellular and molecular architecture of the intestinal stem cell niche	127
Evaluating totipotency using criteria of increasing stringency	121
LC3 lipidation is essential for TFEB activation during the lysosomal damage response to kidney injury	120
Human alveolar type 2 epithelium transdifferentiates into metaplastic KRT5+ basal cells	116
AP-1 imprints a reversible transcriptional programme of senescent cells	116

FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome	115
Mechanical compartmentalization of the intestinal organoid enables crypt folding and collective cell migration	113
PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications	111
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control	111
Liquid-like protein interactions catalyse assembly of endocytic vesicles	109
Single-cell RNA sequencing of blood antigen-presenting cells in severe COVID-19 reveals multi-process defects in antiviral immunity	109
Biophysical properties of AKAP95 protein condensates regulate splicing and tumorigenesis	106
Cell fate coordinates mechano-osmotic forces in intestinal crypt formation	100
A single-cell transcriptomic landscape of the lungs of patients with COVID-19	98
UFMylation maintains tumour suppressor p53 stability by antagonizing its ubiquitination	97
R-loops as Janus-faced modulators of DNA repair	96
Generic nature of the condensed states of proteins	96
The STING phase-separator suppresses innate immune signalling	95
In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states	95
Autophagosome biogenesis comes out of the black box	95
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age	95
lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation	94
Dissecting intratumour heterogeneity of nodal B-cell lymphomas at the transcriptional, genetic and drug-response levels	94
LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapy	93
The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N6-methyladenosine methylation of Parp10 mRNA	91
Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression	91
Asparagine enhances LCK signalling to potentiate CD8+ T-cell activation and anti-tumour responses	90
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis	89
Nuclear F-actin counteracts nuclear deformation and promotes fork repair during replication stress	88
Phase separation of SERRATE drives dicing body assembly and promotes miRNA processing in Arabidopsis	88
Depletion of aneuploid cells in human embryos and gastruloids	87
A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis	87
ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells	86
Extracellular serine controls epidermal stem cell fate and tumour initiation	83
The chromatin remodeler DDM1 prevents transposon mobility through deposition of histone variant H2A.W	80
Enhancer reprogramming driven by high-order assemblies of transcription factors promotes phenotypic plasticity and breast cancer endocrine resistance	80
Metabolic communication in the tumour–immune microenvironment	77
m6A-independent genome-wide METTL3 and METTL14 redistribution drives the senescence-associated secretory phenotype	77
Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance	77
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation	75
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling	74
Heterochromatin establishment during early mammalian development is regulated by pericentromeric RNA and characterized by non-repressive H3K9me3	73
Cell type ontologies of the Human Cell Atlas	73
p27 controls Ragulator and mTOR activity in amino acid-deprived cells to regulate the autophagy–lysosomal pathway and coordinate cell cycle and cell growth	73
Membrane surfaces regulate assembly of ribonucleoprotein condensates	72
Increasing the efficiency and targeting range of cytidine base editors through fusion of a single-stranded DNA-binding protein domain	72
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein	72
An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer	71
STAT3–BDNF–TrkB signalling promotes alveolar epithelial regeneration after lung injury	71
The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC	70
Lipid peroxidation regulates long-range wound detection through 5-lipoxygenase in zebrafish	70
TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis	70