EMBO Reports

Papers
(The median citation count of EMBO Reports is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)
ArticleCitations
Through an ecological lens168
UBAP2L ‐dependent coupling of PLK1 localization and stability during mitosis146
The Golgi microtubules regulate single cell durotaxis130
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation123
SCF FBXW7 regulates G2‐M progression thro120
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment119
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair115
Concerns about academic freedom caused by the Russia–Ukraine War112
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice110
LGBTIQ+N108
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ / BU99
Global and precise identification of functional miRNA targets in mESCs by integrative analysis99
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection97
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of M78
METTL3 protects METTL14 from STUB1 ‐mediated degradation to maintai73
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration71
The mission to ensure continued funding for excellent basic research68
Functional skewing of TRIM21‐SIRT5 interplay dictates IL ‐1β production in 68
The post‐translational regulation of transcription factor EB ( TFEB ) in health and disease68
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis63
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis61
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium57
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus56
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary 54
Somatosensory neurons express specific sets of lincRNAs , and lincRNA CLAP promotes itch sensation53
pH regulates hematopoietic stem cell potential via polyamines53
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation53
Resting natural killer cell homeostasis relies on tryptophan/ NAD + metabolism and HIF 51
Tissue‐like environments shape functional interactions of HIV ‐1 with immature dendritic cells51
Energetic landscape of polycystin channel gating49
Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network47
Striking the right balance between youth and experience47
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates47
PRMT5 links lipid metabolism to contractile function of skeletal muscles47
A Good Day for Helminths: how parasite‐derived GDH suppresses inflammatory responses46
Sci‐Con45
Functions of animal microRNA‐encoded peptides: the race is on!44
Animals do count43
Sequestration of LINE ‐1 in cytosolic aggregates by MOV10 restricts retrotransposition42
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo42
The DEAD box RNA helicase DDX42 is an intrinsic41
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength40
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster40
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis40
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness40
Zika virus alters centrosome organization to suppress the innate immune response39
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis39
Morphofunctional changes at the active zone during synaptic vesicle exocytosis39
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL ‐22 production39
IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation39
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation39
#IchbinHannah and the fight for permanent jobs for postdocs38
Introducing quality measures in an academic research consortium38
Bipolar‐associated miR ‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB238
The regulation of human blastoid research38
DJ‐1 depletion prevents immunoaging in T‐cell compartments37
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association37
Malaria parasites release vesicle subpopulations with signatures of different destinations37
A human coronavirus OC43‐derived polypeptide causes neuropathic pain37
Autophagy orchestrates the crosstalk between cells and organs37
FOXM1 network in association with TREM1 suppression regulates NET f37
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV ‐2 spike36
STAT5b is a key effector of NRG ‐1/ ERBB4 ‐mediated myocardial grow36
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres35
ER ‐phagy: selective autophagy of the endoplasmic reticulum35
Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance35
The GCN2 / eIF2αK stress kinase regulates PP1 t34
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation34
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK234
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1 34
Getting the message right33
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism33
Specific N ‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning33
Gold mining nature for natural products32
Constructive correction32
On predictions and laws in biological evolution32
CACGAACTACCCTAA31
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration31
Inductive prediction in biology31
Understanding redundancy and resilience30
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins30
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses30
Open reading frame dominance indicates protein‐coding potential of RNAs30
CDK9 and PP2A regulate RNA polymerase II30
Pericyte stem cells induce Ly6G + cell accumulation and immunotherapy resistance in pancreatic cancer30
Learning tricks from old dogs29
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood29
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by 29
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria29
Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence29
Neutrophils impose strong immune pressure against PfEMP1 variants implicated in cerebral malaria29
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress28
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation28
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability28
Confusion28
Evolution of pathogen virulence27
The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging27
Scholars in peril: when being a scientist can land you in jail (or worse)27
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H 2 O 2 relea27
KIAA1429 / VIRMA promotes breast cancer progression by m 27
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration27
Phosphorylation by casein kinase 2 enhances the interaction between ER‐phagy receptor TEX264 and ATG8 proteins27
A plea for the ultimate optimism27
Optogenetic control of YAP cellular localisation and function26
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway26
An ULK1 / 2‐PXN mechanotransduction pathway suppresses breast cancer cell migration26
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance26
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation26
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding26
ZBTB2 links p53 deficiency to HIF ‐1‐mediated hypoxia signaling to promote cancer aggressiveness26
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B25
DNA demethylation fine‐tunes IL ‐2 production during thymic regulatory T cell differentiation25
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc25
Autism therapy at crossroads25
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice24
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells24
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcr24
Cx43‐mediated sorting of miRNAs into extracellular vesicles24
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1 /Tip60 complexes to activate 24
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth24
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway24
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state24
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease23
We can do better23
Spns2/ S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis23
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning23
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR + neurons23
The Drosophila mitotic spindle orientation machinery requires activation, not just localization23
MAP kinase cascades in plant development and immune signaling23
MOV10 recruits DCP2 to decap human LINE ‐1 23
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐ RNA<23
Waste management22
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis122
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells22
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation22
The mind of a scientist22
Exosome‐like nanoparticles from Mulberry bark prevent DSS‐induced colitis via the AhR/COPS8 pathway22
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members22
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction22
USP17 is required for peripheral trafficking of lysosomes22
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity22
Ethical aspects of GMO regulation in the EU22
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments21
An RDH‐Plin2 axis modulates lipid droplet size by antagonizing Bmm lipase21
The perceived decline of “disruptive” science and technology21
Piwi/piRNAs control food intake by promoting neuropeptide F expression in locusts21
A trashed treasure21
Keep biology weird21
The chromatin factor ROW cooperates with BEAF ‐32 in regulating long‐range inducible genes21
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice21
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation21
Combining organotypic tissue culture with light‐sheet microscopy ( OTCxLSFM ) to study glioma invasion20
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing20
Lipid and protein content profiling of isolated native autophagic vesicles20
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐1920
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R / TLR20
NPM1 ablation induces HSC aging and inflammation to develop myelodysplastic syndrome exacerbated by p53 loss20
Once in a lifetime20
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon20
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV20
The CRHR1 / CREB / REST signaling cascade regul20
Adult neural stem cells and neurogenesis are resilient to intermittent fasting20
The cancer microbiome20
hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK20
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle20
The taste of vitamin C in Drosophila19
ALS ‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function19
Metabolomics meets systems immunology19
Plasmodium sporozoite disintegration during skin passage limits malaria parasite transmission19
The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes19
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP19
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2 19
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin19
Bioenergetics of early life19
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy19
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases18
Impaired activation of transposable elements in SARS‐CoV ‐2 infection18
Scratching the ocean surface18
FTO negatively regulates the cytotoxic activity of natural killer cells18
Losing bigly18
Myddosome clustering in IL ‐1 receptor signaling regulates the formation of an NF‐kB activating si18
RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells18
Structural basis for specific inhibition of the highly sensitive ShHTL7 receptor18
A short history of beer brewing18
Co‐evolution within the plant holobiont drives host performance18
Metabolic routing maintains the unique fatty acid composition of phosphoinositides17
Targeting human CALR‐mutated MPN progenitors with a neoepitope‐directed monoclonal antibody17
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface17
Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins17
Trained immunity induced by high‐salt diet impedes stroke recovery17
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells17
Nutrition, metabolism, and epigenetics: pathways of circadian reprogramming17
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis17
Extracellular vesicles from malaria‐infected red blood cells: not all are secreted equal17
Lamarck redux and other false arguments against SARS‐CoV‐2 vaccination17
Centrosome linker protein C‐Nap1 maintains stem cells in mouse testes17
Constricted migration is associated with stable 3D genome structure differences in cancer cells17
The international of wisdom17
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin16
UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture16
Transforming primary human hepatocytes into hepatocellular carcinoma with genetically defined factors16
Threatened forests16
Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV ‐2 in children16
Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia16
The nucleolar protein GNL3 prevents resection of stalled replication forks16
The structure of fly Teneurin‐m reveals an asymmetric self‐assembly that allows expansion into zippers16
Nsp16 shields SARS–CoV ‐2 from efficient MDA5 sensing and IFIT1 16
Lysosomal K + channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease16
The fate of surplus laboratory animals16
Loss of primary cilia promotes inflammation and carcinogenesis15
Legionella ‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling15
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R 15
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1   mRNA 15
Let's bring games into university classrooms15
Reconsidering editorial consideration15
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization15
CTCF shapes chromatin structure and gene expression in health and disease15
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration15
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in ye15
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis15
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐6715
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite15
ABCB ‐mediated shootward auxin transport feeds into the root clock15
Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint15
Stalking the link between reproduction and aging15
A quantitative fluorescence‐based approach to study mitochondrial protein import15
Architecture for research15
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development15
A20 controls RANK ‐dependent osteoclast formation and bone physiology15
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES115
The Russian invasion of Ukraine: a humanitarian tragedy and a tragedy for science14
C9orf72 protein quality control by UBR5 ‐mediated heterotypic ubiquitin chains14
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum14
Western science funders’ response to Russia’s invasion of Ukraine14
HP1 maintains protein stability of H3K9 methyltransferases and demethylases14
Dynamics of SLC25A51 reveal preference for oxidized NAD + and subst14
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish14
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease14
Ethanolamine‐phosphate on the second mannose is a preferential bridge for some GPI‐anchored proteins14
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing14
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis14
The piano and the pianist14
SIRT3 ‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth14
Structural insights into the assembly and activation of the IL ‐27 signaling complex14
(Free) Creative Commons content on the internet is not so free after all13
Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans13
The plant FYVE domain‐containing protein FREE1 associates with microprocessor components to repres13
Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL13
O ‐GlcNAcylation promotes topoisomerase IIα c13
Cognition: from the cosmos down to molecules – and back13
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