EMBO Reports

Article	Citations
METTL3 protects METTL14 from STUB1 ‐mediated degradation to maintai	205
LGBTIQ+N	148
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	146
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	146
The Golgi microtubules regulate single cell durotaxis	140
The mission to ensure continued funding for excellent basic research	135
Through an ecological lens	125
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	121
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	119
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	115
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ / BU	115
SCF FBXW7 regulates G2‐M progression thro	97
UBAP2L ‐dependent coupling of PLK1 localization and stability during mitosis	88
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice	77
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	76
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of M	75
The post‐translational regulation of transcription factor EB ( TFEB ) in health and disease	69
Functional skewing of TRIM21‐SIRT5 interplay dictates IL ‐1β production in	66
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	64
The transcriptional regulator Sin3A balances IL‐17A and Foxp3 expression in primary	63
Blood flow diverts extracellular vesicles from endothelial degradative compartments to promote angiogenesis	60
Striking the right balance between youth and experience	59
Animals do count	55
Tissue‐like environments shape functional interactions of HIV ‐1 with immature dendritic cells	54
Noncanonical Wnt signaling promotes colon tumor growth, chemoresistance and tumor fibroblast activation	54

Rapid evolutionary repair by secondary perturbation of a primary disrupted transcriptional network	53
Zika virus alters centrosome organization to suppress the innate immune response	53
Sequestration of LINE ‐1 in cytosolic aggregates by MOV10 restricts retrotransposition	51
Energetic landscape of polycystin channel gating	50
Somatosensory neurons express specific sets of lincRNAs , and lincRNA CLAP promotes itch sensation	47
The DEAD box RNA helicase DDX42 is an intrinsic	47
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	47
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	46
Microtubules are not required to generate a nascent axon in embryonic spinal neurons in vivo	46
Resting natural killer cell homeostasis relies on tryptophan/ NAD + metabolism and HIF	46
PRMT5 links lipid metabolism to contractile function of skeletal muscles	45
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	44
pH regulates hematopoietic stem cell potential via polyamines	43
Evolutionary remodelling of N‐terminal domain loops fine‐tunes SARS‐CoV ‐2 spike	43
IL ‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation	43
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	43
Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster	43
The regulation of human blastoid research	42
Introducing quality measures in an academic research consortium	42
The fin roundabout: Slit‐Robo and S1P signaling coordinate fin morphogenesis	42
The GCN2 / eIF2αK stress kinase regulates PP1 t	41
Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs–NLRC4 association	41
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres	40
Bipolar‐associated miR ‐499‐5p controls neuroplasticity by downregulating the Cav1.2 subunit CACNB2	40
FOXM1 network in association with TREM1 suppression regulates NET f	39
STAT5b is a key effector of NRG ‐1/ ERBB4 ‐mediated myocardial grow	39
A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation	39
Specific N ‐glycans regulate an extracellular adhesion complex during somatosensory dendrite patterning	38
GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1	38
Malaria parasites release vesicle subpopulations with signatures of different destinations	38
BTNL2 promotes colitis‐associated tumorigenesis in mice by regulating IL ‐22 production	37
Autophagy orchestrates the crosstalk between cells and organs	37
Tick‐borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2	36
Single cell clonal analysis identifies an AID ‐dependent pathway of plasma cell differentiation	36
ER ‐phagy: selective autophagy of the endoplasmic reticulum	36
Tonic TNF conditioning of macrophages safeguards stimulus‐specific inflammatory responses	35
Getting the message right	35
Ovol1/2 loss‐induced epidermal defects elicit skin immune activation and alter global metabolism	35
Inductive prediction in biology	34
Gold mining nature for natural products	34
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration	34
Constructive correction	34
Pericyte stem cells induce Ly6G + cell accumulation and immunotherapy resistance in pancreatic cancer	34
CDK9 and PP2A regulate RNA polymerase II	33
mPFC DUSP1 mediates adolescent cocaine exposure‐induced higher sensitivity to drug in adulthood	33
TMBIM5 is the Ca 2+ /H + antiporter of mammalian mitochondria	32
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins	32
The Autophagy Receptor TAX1BP1 ( T6BP ) improves antigen presentation by	32
Adaptation delay causes a burst of mutations in bacteria responding to oxidative stress	31
Confusion	31

The extracellular matrix fibulin 7 maintains epidermal stem cell heterogeneity during skin aging	31
Learning tricks from old dogs	31
KIAA1429 / VIRMA promotes breast cancer progression by m	31
NuRD‐independent Mi‐2 activity represses ectopic gene expression during neuronal maturation	31
Reducing oxidative protein folding alleviates senescence by minimizing ER‐to‐nucleus H 2 O 2 relea	30
An ULK1 / 2‐PXN mechanotransduction pathway suppresses breast cancer cell migration	30
Scholars in peril: when being a scientist can land you in jail (or worse)	30
Chronic inflammation decreases HSC fitness by activating the druggable Jak/Stat3 signaling pathway	30
Evolution of pathogen virulence	30
PLK1 promotes the mitotic surveillance pathway by controlling cytosolic 53BP1 availability	30
GM‐CSF suppresses antioxidant signaling and drives IL‐1β secretion through NRF2 downregulation	29
Cx43‐mediated sorting of miRNAs into extracellular vesicles	29
A plea for the ultimate optimism	29
ZBTB2 links p53 deficiency to HIF ‐1‐mediated hypoxia signaling to promote cancer aggressiveness	29
Autism therapy at crossroads	29
Optogenetic control of YAP cellular localisation and function	29
Phosphatidylserine clustering by the Ebola virus matrix protein is a critical step in viral budding	29
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	29
Circadian oscillation in primary cilium length by clock genes regulates fibroblast cell migration	29
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	28
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	28
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	28
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state	28
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcr	28
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	27
DNA demethylation fine‐tunes IL ‐2 production during thymic regulatory T cell differentiation	27
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	27
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	27
Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members	27
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1 /Tip60 complexes to activate	27
Chemical conversion of human conventional PSCs to TSCs following transient naive gene activation	26
The mind of a scientist	26
MOV10 recruits DCP2 to decap human LINE ‐1	26
Structural insights into coordinating 5S RNP rotation with ITS2 pre‐ RNA<	26
Spns2/ S1P : it takes two to tango with inflammation and metabolic rewiring during sepsis	26
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR + neurons	26
We can do better	26
Waste management	26
The Drosophila mitotic spindle orientation machinery requires activation, not just localization	25
Keep biology weird	25
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity	25
Ethical aspects of GMO regulation in the EU	25
The perceived decline of “disruptive” science and technology	25
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	25
The chromatin factor ROW cooperates with BEAF ‐32 in regulating long‐range inducible genes	25
A trashed treasure	24
Combining organotypic tissue culture with light‐sheet microscopy ( OTCxLSFM ) to study glioma invasion	24
Differential roles of the fish chitinous membrane in gut barrier immunity and digestive compartments	24
Estrogen receptor alpha signaling in dendritic cells modulates autoimmune disease phenotype in mice	24
Lipid and protein content profiling of isolated native autophagic vesicles	24
The CRHR1 / CREB / REST signaling cascade regul	23
EHD1 promotes CP110 ubiquitination by centriolar satellite delivery of HERC2	23
Bioenergetics of early life	23
hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK	23
Structural study of UFL1‐UFC1 interaction uncovers the role of UFL1 N‐terminal helix in ufmylation	23
Adult neural stem cells and neurogenesis are resilient to intermittent fasting	23
Co‐evolution within the plant holobiont drives host performance	23
Once in a lifetime	23
The cancer microbiome	23
Intracellular growth of Brucella is mediated by Dps‐dependent activation of ferritinophagy	23
The taste of vitamin C in Drosophila	22
Myddosome clustering in IL ‐1 receptor signaling regulates the formation of an NF‐kB activating si	22
Bassoon controls synaptic vesicle release via regulation of presynaptic phosphorylation and cAMP	22
Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV	22
ALS ‐linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain‐of‐function	22
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19	22
Cancer‐cell‐secreted extracellular vesicles target p53 to impair mitochondrial function in muscle	21
Lipin‐2 regulates the antiviral and anti‐inflammatory responses to interferon	21
Candida albicans induces neutrophil extracellular traps and leucotoxic hypercitrullination via candidalysin	21
Akkermansia muciniphila induces slow extramedullary hematopoiesis via cooperative IL‐1R / TLR	21
The obesity‐linked human lncRNA AATBC stimulates mitochondrial function in adipocytes	21
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing	21
Metabolic routing maintains the unique fatty acid composition of phosphoinositides	20
Scratching the ocean surface	20
Dengue virus NS1 protein conveys pro‐inflammatory signals by docking onto high‐density lipoproteins	20
Metabolomics meets systems immunology	20
RAB11A and RAB11B control mitotic spindle function in intestinal epithelial progenitor cells	20
Trained immunity induced by high‐salt diet impedes stroke recovery	20
Frizzled receptors facilitate Tiki inhibition of Wnt signaling at the cell surface	20
FTO negatively regulates the cytotoxic activity of natural killer cells	20

Centrosome linker protein C‐Nap1 maintains stem cells in mouse testes	20
A short history of beer brewing	20
Losing bigly	20
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells	19
The international of wisdom	19
Extracellular vesicles from malaria‐infected red blood cells: not all are secreted equal	19
Retrotransposon insertions associated with risk of neurologic and psychiatric diseases	19
Lysosomal K + channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinson's disease	19
Constricted migration is associated with stable 3D genome structure differences in cancer cells	19
Impaired activation of transposable elements in SARS‐CoV ‐2 infection	19
Immune–epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV ‐2 in children	19
The structure of fly Teneurin‐m reveals an asymmetric self‐assembly that allows expansion into zippers	18
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	18
Nsp16 shields SARS–CoV ‐2 from efficient MDA5 sensing and IFIT1	18
Cryo‐EM structure of the octameric pore of Clostridium perfringens β‐toxin	18
Legionella ‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	18
Metabolic plasticity sustains the robustness of Caenorhabditis elegans embryogenesis	18
UBQLN2 and HSP70 participate in Parkin‐mediated mitophagy by facilitating outer mitochondrial membrane rupture	18
The fate of surplus laboratory animals	18
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1   mRNA	18
Threatened forests	18
A20 controls RANK ‐dependent osteoclast formation and bone physiology	17
Loss of primary cilia promotes inflammation and carcinogenesis	17
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	17
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in ye	17
Let's bring games into university classrooms	17
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	17
ABCB ‐mediated shootward auxin transport feeds into the root clock	17
The nucleolar protein GNL3 prevents resection of stalled replication forks	17
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	17
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	17
CTCF shapes chromatin structure and gene expression in health and disease	17
Reconsidering editorial consideration	17
A quantitative fluorescence‐based approach to study mitochondrial protein import	17
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	16
Pseudomonas aeruginosa LecB suppresses immune responses by inhibiting transendothelial migration	16
PcEiger links the Imd/Relish pathway to ROS production in the intestine of the red swamp crayfish	16
UNC13D inhibits STING signaling by attenuating its oligomerization on the endoplasmic reticulum	16
Something new under the sun: caspases promote cell survival under moderate heat stress	16
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis	16
The piano and the pianist	16
C9orf72 protein quality control by UBR5 ‐mediated heterotypic ubiquitin chains	16
Paraspeckles interact with SWI/SNF subunit ARID1B to regulate transcription and splicing	16
SIRT3 ‐dependent delactylation of cyclin E2 prevents hepatocellular carcinoma growth	16
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R	16
Dynamics of SLC25A51 reveal preference for oxidized NAD + and subst	16
Reverse electron transfer is activated during aging and contributes to aging and age‐related disease	16
Stalking the link between reproduction and aging	16
Structural insights into the assembly and activation of the IL ‐27 signaling complex	16
LRH ‐1/ NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance	15
Late‐termination of pregnancy for medical reasons: when abortion isn’t really by choice	15
Interferon‐induced transmembrane protein 3 (IFITM3) limits lethality of SARS‐CoV‐2 in mice	15
From pollutant to powerhouse	15
Functional platelet‐derived mitochondria induce the release of human neutrophil microvesicles	15
Cognition: from the cosmos down to molecules – and back	15
The cost of living	15
I was born this way	15
Ethanolamine‐phosphate on the second mannose is a preferential bridge for some GPI‐anchored proteins	15
How to avoid mistakes in science publications	15
53BP1 ‐mediated recruitment of RASSF1A to ribosomal DNA breaks prom	15
Intervention	15
Open Access for Open Science	15
Dissecting the cotranscriptome landscape of plants and their microbiota	15
The plant FYVE domain‐containing protein FREE1 associates with microprocessor components to repres	15
ER ‐mitochondria contacts and cholesterol metabolism are disrupted by disease‐associated tau protein	14
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination	14
T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction	14
Local and systemic effects of microbiome‐derived metabolites	14
The fountain of youth of mitochondrial research	14
(Free) Creative Commons content on the internet is not so free after all	14
The mechanosensitive TRPV2 calcium channel promotes human melanoma invasiveness and metastatic potential	14
Presynaptic cGMP sets synaptic strength in the striatum and is important for motor learning	14
O ‐GlcNAcylation promotes topoisomerase IIα c	14
Sphingosine‐1‐phosphate controls endothelial sphingolipid homeostasis via ORMDL	14
Desert plants to stop desertification	14
A CcdB toxin‐derived peptide acts as a broad‐spectrum antibacterial therapeutic in infected mice	14
Orchestrating vesicular and nonvesicular membrane dynamics by intrinsically disordered proteins	14
LINC00493‐encoded microprotein SMIM26 exerts anti‐metastatic activity in renal cell carcinoma	14
Genome‐wide association and environmental suppression of the mortal germline phenotype of wild C. elegans	14
Mitigating the ecological collapse of coral reef ecosystems	14
A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis	14
The Preprint Club	13
Old and newly synthesized histones are asymmetrically distributed in Drosophila intestinal stem cell divisions	13
Antiviral activity of the human endogenous retrovirus‐R envelope protein against SARS‐CoV‐2	13
Calculation of ATP production rates using the Seahorse XF Analyzer	13
In viral games, refs go to the replay	13
TRAPPC1 is essential for the maintenance and differentiation of common myeloid progenitors in mice	13
Rassf7a promotes spinal cord regeneration and controls spindle orientation in neural progenitor cells	13
The polyA tail facilitates splicing of last introns with weak 3′ splice sites via PABPN1	13
“Seek simplicity and distrust it”	13
Science after Brexit: bright spots on the Horizon?	13
Low hanging fruit for combatting SARS‐CoV‐2?	13
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium	13
MARCH5 promotes STING pathway activation by suppressing polymer formation of oxidized STING	13
Asexuality in Drosophila juvenile males is organizational and independent of juvenile hormone	13