OOIR: Observatory of International Research

Papers

(The TQCC of EMBO Reports is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Developmental cell death of cortical projection neurons is controlled by a Bcl11a/Bcl6‐dependent pathway	158
Super‐resolution microscopy reveals focal organization of ER‐associated Y‐complexes in mitosis	135
High‐resolution structure of native toxin A from Clostridioides difficile	105
Hedgehog signaling can enhance glycolytic ATP production in the Drosophila wing disc	103
Feasibility and impact of haplogroup matching for mitochondrial replacement treatment	101
Piwil2 (Mili) sustains neurogenesis and prevents cellular senescence in the postnatal hippocampus	97
piRNA‐ and siRNA‐mediated transcriptional repression in Drosophila , mice, and yeast: new insights and biodiversity	97
Concerns about academic freedom caused by the Russia–Ukraine War	92
The coordination of spindle‐positioning forces during the asymmetric division of the Caenorhabditis elegans zygote	86
SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3	83
SCF ^FBXW7 regulates G2‐M progression through control of CCNL1	82
Nlrp3 inflammasome activation in macrophages suffices for inducing autoinflammation in mice	81
Dynamic chromosomal interactions and control of heterochromatin positioning by Ki‐67	79
The nucleolar protein GNL3 prevents resection of stalled replication forks	79
Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair	78
Ub and Dub of RNF43/ZNRF3 in the WNT signalling pathway	77
OCRL regulates lysosome positioning and mTORC1 activity through SSX2IP‐mediated microtubule anchoring	77
Identification and characterization of in vitro expanded hematopoietic stem cells	76
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B	74
Natural probiotics improve heritable sterility	70
Cohesin contributes to transcriptional repression of stage‐specific genes in the human malaria parasite	67
The human touch	65
Cardio‐respiratory and phenotypic rescue of dystrophin/utrophin‐deficient mice by combination therapy	64
An ongoing science‐society‐ethics experiment	62
Working in close quarters: biparental meiosis in the oocyte	61

Filling an ARHGAP in our knowledge of human brain evolution	60
Let's bring games into university classrooms	58
Reconsidering editorial consideration	58
The most unkindest cut	57
A congenital hydrocephalus‐causing mutation in Trim71 induces stem cell defects via inhibiting Lsd1 mRNA translation	56
Changes in lipid metabolism driven by steroid signalling modulate proteostasis in C. elegans	55
Glycolytic Pfkp acts as a Lin41 protein kinase to promote endodermal differentiation of embryonic stem cells	54
The interactomics of academia	51
LGBTIQ+N	50
Architecture for research	49
Autism therapy at crossroads	49
Mefloquine targets NLRP3 to reduce lipopolysaccharide‐induced systemic inflammation and neural injury	48
The four fronts of immunotherapy	48
COVID‐19 and the gain of function debates	48
Sox7‐positive endothelial progenitors establish coronary arteries and govern ventricular compaction	47
Work life balance?	47
NeutrobodyPlex—monitoring SARS‐CoV‐2 neutralizing immune responses using nanobodies	46
Single‐cell transcriptomic landscape of cardiac neural crest cell derivatives during development	45
LTK and ALK promote neuronal polarity and cortical migration by inhibiting IGF1R activity	45
Parkin coordinates mitochondrial lipid remodeling to execute mitophagy	44
The underappreciated art of creating publication‐quality figures	44
IKKβ is required for the formation of the NLRP3 inflammasome	44
MYB sustains hypoxic survival of pancreatic cancer cells by facilitating metabolic reprogramming	42
Endothelial cell‐derived oxysterol ablation attenuates experimental autoimmune encephalomyelitis	42
m6A methylation promotes white‐to‐beige fat transition by facilitating Hif1a translation	41
Two structurally defined Aβ polymorphs promote different pathological changes in susceptible mice	41
Regional heterogeneity of astrocyte morphogenesis dictated by the formin protein, Daam2, modifies circuit function	41
Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis	41
An exon junction complex‐independent function of Barentsz in neuromuscular synapse growth	40
A force balance model for a cell size‐dependent meiotic nuclear oscillation in fission yeast	39
DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation	39
Light disrupts social memory via a retina‐to‐supraoptic nucleus circuit	39
Equally potent: Nlrp3 mutation in macrophages or neutrophils is sufficient to drive autoinflammation	39
A20 controls RANK ‐dependent osteoclast formation and bone physiology	38
SDGs in new‐media arts for science	38
TERT activates endogenous retroviruses to promote an immunosuppressive tumour microenvironment	38
Shade‐induced lncRNAPUAR promotes shade response by repressing PHYA expression	38
Metabolic resistance to the inhibition of mitochondrial transcription revealed by CRISPR‐Cas9 screen	37
Branched‐chain amino acid synthesis is coupled to TOR activation early in the cell cycle in yeast	37
RGCC balances self‐renewal and neuronal differentiation of neural stem cells in the developing mammalian neocortex	37
Are doping tests in sports trustworthy?	37
CCR4‐NOT differentially controls host versus virus poly(a)‐tail length and regulates HCMV infection	37
UBAP2L‐dependent coupling of PLK1 localization and stability during mitosis	37
PLK1‐dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV‐infected mice	37
Interferon‐induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20	36
PML‐NB‐dependent type I interferon memory results in a restricted form of HSV latency	36
TPLATE complex‐dependent endocytosis attenuates CLAVATA1 signaling for shoot apical meristem maintenance	36
Cx43‐mediated sorting of miRNAs into extracellular vesicles	36
Dynamin‐like proteins mediate extracellular vesicle secretion in Mycobacterium tuberculosis	36
Deregulations of miR‐1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1	36

Break‐induced RNA–DNA hybrids (BIRDHs) in homologous recombination: friend or foe?	35
SCAI promotes error‐free repair of DNA interstrand crosslinks via the Fanconi anemia pathway	35
A quantitative fluorescence‐based approach to study mitochondrial protein import	35
Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4	35
Loss of primary cilia promotes inflammation and carcinogenesis	35
Myeloid cell‐specific topoisomerase 1 inhibition using DNA origami mitigates neuroinflammation	34
Phosphorylation of myosin A regulates gliding motility and is essential for Plasmodium transmission	33
How physical forces drive the process of helical membrane protein folding	33
A systematic analysis of microtubule‐destabilizing factors during dendrite pruning in Drosophila	33
USP3 plays a critical role in the induction of innate immune tolerance	33
Through an ecological lens	33
E3 ubiquitin ligase NEDD4L negatively regulates inflammation by promoting ubiquitination of MEKK2	32
DDX60 selectively reduces translation off viral type II internal ribosome entry sites	32
Global and precise identification of functional miRNA targets in mESCs by integrative analysis	32
Tissue resilience: lessons from social resilience	31
Overlapping roles for PLK1 and aurora A during meiotic centrosome biogenesis in mouse spermatocytes	31
POGZ promotes homology‐directed DNA repair in an HP1‐dependent manner	31
Remodeling and activation mechanisms of outer arm dyneins revealed by cryo‐EM	31
LncRNA‐PAGBC acts as a microRNA sponge and promotes gallbladder tumorigenesis	31
BRD9 is a druggable component of interferon‐stimulated gene expression and antiviral activity	31
Diacylglycerols interact with the L2 lipidation site in TRPC3 to induce a sensitized channel state	31
The Golgi microtubules regulate single cell durotaxis	31
Legionella‐ and host‐driven lipid flux at LCV‐ER membrane contact sites promotes vacuole remodeling	30
CircHIPK3 sponges miR ‐558 to suppress heparanase expression in bladder cancer cells	30
Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis	30
Rab21 regulates caveolin‐1‐mediated endocytic trafficking to promote immature neurite pruning	29
Goliath induces inflammation in obese mice by linking fatty acid β‐oxidation to glycolysis	29
Regulation of cGAS activity by RNA‐modulated phase separation	29
Muscle‐derived exophers promote reproductive fitness	29
Snail enhances arginine synthesis by inhibiting ubiquitination‐mediated degradation of ASS1	29
The anti‐apoptotic Bcl‐2 protein regulates hair follicle stem cell function	28
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth	28
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis	28
A dual‐function SNF2 protein drives chromatid resolution and nascent transcript removal in mitosis	28
Human mitochondrial ADP/ATP carrier SLC25A4 operates with a ping‐pong kinetic mechanism	27
Loss of renal tubular G9a benefits acute kidney injury by lowering focal lipid accumulation via CES1	27
DNA damage response at telomeres boosts the transcription of SARS‐CoV‐2 receptor ACE2 during aging	27
The P4‐ATPase Drs2 interacts with and stabilizes the multisubunit tethering complex TRAPPIII in yeast	27
RNA polymerase II CTD is dispensable for transcription and required for termination in human cells	27
ORF3c is expressed in SARS‐CoV‐2‐infected cells and inhibits innate sensing by targeting MAVS	27
METTL3 protects METTL14 from STUB1‐mediated degradation to maintain m⁶A homeostasis	27
Histone remodeling reflects conserved mechanisms of bovine and human preimplantation development	27
LINC00839 promotes colorectal cancer progression by recruiting RUVBL1/Tip60 complexes to activate NRF1	26
A gene subset requires CTCF bookmarking during the fast post‐mitotic reactivation of mouse ES cells	26
Melanopsin elevates locomotor activity during the wake state of the diurnal zebrafish	26
High salt activates p97 to reduce host antiviral immunity by restricting Viperin induction	26
The stress granule protein G3BP1 promotes pre‐condensation of cGAS to allow rapid responses to DNA	25
FBL promotes cancer cell resistance to DNA damage and BRCA1 transcription via YBX1	25
Hyperosmotic stress induces 2‐cell‐like cells through ROS and ATR signaling	25
The post‐translational regulation of transcription factor EB (TFEB) in health and disease	25
Mad2 promotes Cyclin B2 recruitment to the kinetochore for guiding accurate mitotic checkpoint	25
DOT1L activity affects neural stem cell division mode and reduces differentiation and ASNS expression	25
MAP kinase cascades in plant development and immune signaling	25
eIF4EHP promotes Ldh mRNA translation in and fruit fly adaptation to hypoxia	25
Mitochondrial F ₁ F _O ATP synthase determines the local proton motive force at cristae rims	25
Specific RNA interactions promote TDP‐43 multivalent phase separation and maintain liquid properties	25
Non‐redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression	24
Bioremediation of cyanide‐containing wastes	24
Cytotoxic T lymphocytes require transcription for infiltration but not target cell lysis	24
TRPV1 sustains microglial metabolic reprogramming in Alzheimer's disease	24
ABCB‐mediated shootward auxin transport feeds into the root clock	24
HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions	24
CIP2A deficiency promotes depression‐like behaviors in mice through inhibition of dendritic arborization	24
The mission to ensure continued funding for excellent basic research	24
IP6‐stabilised HIV capsids evade cGAS/STING‐mediated host immune sensing	24
XIAP promotes melanoma growth by inducing tumour neutrophil infiltration	24
lncRNA‐encoded pep‐AP attenuates the pentose phosphate pathway and sensitizes colorectal cancer cells to Oxaliplatin	23
mTORC1 activity negatively regulates human hair follicle growth and pigmentation	23
UBR‐1 ubiquitin ligase regulates the balance between GABAergic and glutamatergic signaling	23
CTCF shapes chromatin structure and gene expression in health and disease	23
POPDC1 scaffolds a complex of adenylyl cyclase 9 and the potassium channel TREK‐1 in heart	23
Structural basis for the specificity of PPM1H phosphatase for Rab GTPases	23
Fusobacterium nucleatum secretes amyloid‐like FadA to enhance pathogenicity	23
Expanded tRNA methyltransferase family member TRMT9B regulates synaptic growth and function	23
Aire‐dependent transcripts escape Raver2‐induced splice‐event inclusion in the thymic epithelium	23
The ubiquitin ligation machinery in the defense against bacterial pathogens	22
KLF10 promotes nonalcoholic steatohepatitis progression through transcriptional activation of zDHHC7	22
Long‐distance mobile mRNA CAX3 modulates iron uptake and zinc compartmentalization	22
Pseudomonas aeruginosaLecB suppresses immune responses by inhibiting transendothelial migration	22
Molecular mechanisms of TWIST1‐regulated transcription in EMT and cancer metastasis	22

EI24 promotes cell adaption to ER stress by coordinating IRE1 signaling and calcium homeostasis	22
Regeneration in starved planarians depends on TRiC/CCT subunits modulating the unfolded protein response	22
Unexpected gene activation following CRISPR‐Cas9‐mediated genome editing	21
Endophilin A2 regulates B‐cell endocytosis and is required for germinal center and humoral responses	21
Waste management	21
Combined measures	21
Spns2/S1P: it takes two to tango with inflammation and metabolic rewiring during sepsis	21
Nuclear Dishevelled targets gene regulatory regions and promotes tumor growth	21
The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive‐strand R	21
The mind of a scientist	21
The piano and the pianist	21
Single‐cell analysis reveals dynamic changes of neural cells in developing human spinal cord	21
Somatosensory neurons express specific sets of lincRNAs, and lincRNA CLAP promotes itch sensation in mice	21
SPTing across condensates: SEC‐mediated translocation of SPT complex from pausing condensates to elongation condensates	21
Morphofunctional changes at the active zone during synaptic vesicle exocytosis	21
Undergraduate students in research	20
miR‐AB, a miRNA‐based shRNA viral toolkit for multicolor‐barcoded multiplex RNAi at a single‐cell level	20
Viperin—taken down with a pinch of salt	20
A NANOG‐pERK reciprocal regulatory circuit regulates Nanog autoregulation and ERK signaling dynamics	20
Money, power, and mitochondria	20
We can do better	20
Sci‐Con	20
Animals do count	20
Striking the right balance between youth and experience	20
The Russian invasion of Ukraine: a humanitarian tragedy and a tragedy for science	20
Homologous recombination is reduced in female embryonic stem cells by two active X chromosomes	20
Descending dopaminergic pathway facilitates itch signal processing via activating spinal GRPR⁺ neurons	20
Male infertility‐associated Ccdc108 regulates multiciliogenesis via the intraflagellar transport machinery	19
A species by any other name would sound as sweet	19
Limiting hESC patents in China under a dual‐value perspective	19
Fatty acid oxidation is required for embryonic stem cell survival during metabolic stress	19
Lysosome positioning and mTOR activity in Lowe syndrome	19
XAF1 prevents hyperproduction of type I interferon upon viral infection by targeting IRF7	19
A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength	19
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures	19
The androgen receptor depends on ligand‐binding domain dimerization for transcriptional activation	18
The SUMO protease SENP3 regulates mitochondrial autophagy mediated by Fis1	18
The splicing‐regulatory lncRNA NTRAS sustains vascular integrity	18
A genome‐wide association study identifies a transporter for zinc uploading to maize kernels	18
LincRNA‐EPS impairs host antiviral immunity by antagonizing viral RNA–PKR interaction	18
C9orf72 protein quality control by UBR5‐mediated heterotypic ubiquitin chains	18
Foxd3 controls heterochromatin‐mediated repression of repeat elements and 2‐cell state transcription	18
BioID reveals an ATG9A interaction with ATG13‐ATG101 in the degradation of p62/SQSTM1‐ubiquitin clusters	18
Dynamics of SLC25A51 reveal preference for oxidized NAD⁺ and substrate led transport	18
The RNA polymerase II subunit Rpb9 activates ATG1 transcript	18
Endothelial‐immune crosstalk contributes to vasculopathy in nonalcoholic fatty liver disease	18
pH regulates hematopoietic stem cell potential via polyamines	18
Pyruvate metabolism guides definitive lineage specification during hematopoietic emergence	18
Aurora Kinase A proximity map reveals centriolar satellites as regulators of its ciliary function	18
Scalable RT‐LAMP‐based SARS‐CoV‐2 testing for infection surveillance with applications in pandemic preparedness	18
Reduced symmetric dimethylation stabilizes vimentin and promotes metastasis in MTAP‐ deficient lung cancer	18
Molecular view of ER membrane remodeling by the Sec61/TRAP translocon	17
Transgenerational epigenetic information through the sperm	17
Defective branched‐chain amino acid catabolism in dorsal root ganglia contributes to mechanical pain	17
Tetracyclines activate mitoribosome quality control and reduce ER stress to promote cell survival	17
USP17 is required for peripheral trafficking of lysosomes	17
Zika virus alters centrosome organization to suppress the innate immune response	17
Oxygen‐regulated post‐translation modifications as master signalling pathway in cells	17
Reprogramming of glucocorticoid receptor function by hypoxia	17
Rubble to Rouble: how can science respond to war?	17
Aurora B‐dependent polarization of the cortical actomyosin network during mitotic exit	17
Differential phosphorylation of Clr4^SUV39H by Cdk1 accompanies a histone H3 methylation switch that is essential for gametogenesis	17
Dynamic reversibility of α‐synuclein serine‐129 phosphorylation is impaired in synucleinopathy models	17