OOIR: Observatory of International Research

Papers

(The TQCC of Reproduction is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Specc1l deficiency leads to abnormal oocyte meiosis and reduced blastocyst development in mouse	120
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa	83
Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation	75
A proposed model of a clock that governs the length of human pregnancy	72
Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review	57
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample	54
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	45
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway	44
How, where and when is SPINK3 bound and removed from mouse sperm?	38
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation	38
Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause	36
High-lipid nutritional environment in different ontogenetic periods induce developmental programming of rat prostate at aging	34
Ca2+ concentrations in mouse sperm mitochondria fluctuate according to the cytosol	32
Superovulation-induced changes in murine ovarian perifollicular angiogenesis	31
A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle	31
Fertility Treatment and Preservation Options for Transgender and Gender Diverse People	30
Scientific contributions of Professor Sir Ian Wilmut	28
Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome	28
Environmental constraints and pathologies that modulate equine placental genes and development	27
Ram sperm and seminal plasma alter immune transcriptome and cytokine secretion in ovine cervical explants ex vivo	26
A scoping review regarding reproductive capacity modulation based on alpha-ketoglutarate supplementation	24
Telomeres and oocyte maturation rate are not reduced by COVID-19 except in severe cases	23
Glucose metabolism disorder related to follicular fluid exosomal miR-122-5p in cumulus cells of endometriosis patients	21
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques	21
The effects of the activation of TLR2/TLR1 on in vitro angiogenesis in an immortalized ovine luteal endothelial cell line	20

The role of angiotensin II and relaxin in vascular adaptation to pregnancy	19
Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?	19
Murine models of advanced maternal age: a systematic review and meta-analysis	19
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The impact of polycystic ovary syndrome on reproductive health: a narrative review	18
Gadd45g is required for timely Sry expression independently of RSPO1 activity	18
Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI	18
Highly expressed lncRNA H19 in endometriosis promotes aerobic glycolysis and histone lactylation	17
Regulation of testosterone synthesis in Leydig cells by ClC-2 chloride channel	17
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology	17
Molecular functions of Mrhl lncRNA in mouse spermatogenesis	17
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation	16
The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesis	16
Acbp is essential for decidualization during early pregnancy in mice	16
SPERM FACTORS AND EGG ACTIVATION: Fertilization failure after human ICSI and the clinical potential of PLCZ1	16
Ultrastructural cilia defects in multi-ciliated uterine glandular epithelial cells from women with reproductive failure	16
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The significance of functional adrenal hyperandrogenism in polycystic ovary syndrome across the lifespan	14
Novel insight into CD90 mesenchymal stem cell marker in mouse endometrial stroma during embryo implantation	14
The reduction of oocytes and disruption of the meiotic prophase I in Fanconi anemia E-deficient mice	14
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Mind the gap: a nationwide audit of LGBTQ+ inclusion in fertility care providers in the United Kingdom	14
mTORC1-dependent suppression of autophagic activity in somatic cell nuclear transfer mouse embryos	14
Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells	13
Pregnancy preparation: redistribution of CCR7-positive cells in the rat uterus	13
Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome	13
Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows	13
Extracellular vesicles improve embryo cryotolerance by maintaining the tight junction integrity during blastocoel re-expansion	13
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPROSURES ON REPRODUCTION: Adverse impacts of particulate matter air pollution on female and male reproduction	12
Characterization of ovarian progenitor cells for their potential to generate steroidogenic theca cells in vitro	12
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs	12
Involvement of the Linker Histone H1Foo in the Regulation of Oogenesis	12
Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures	12
Investigating ticagrelor in a preclinical pipeline as a novel therapeutic to prevent preterm birth	12
T2DM-elicited oxidative stress represses MTA3 expression in mouse Leydig cells	12
DCAF13 and RNF114 participate in the regulation of early porcine embryo development	12
Monoclonal antibody potentiating gonadotropin activity in vitro and in vivo in male and female rats and in ewes	12
SPERM FACTORS AND EGG ACTIVATION: PLCzeta as the sperm factor that activates eggs: 20 years on	12
miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation	11
Reproductive Ageing: Declining translational capacity as a potential driver for oocyte meiotic instability	11
A maternal ketogenic diet alters oviduct fluid nutrients and embryo histone acetylation in mice	11
Epigallocatechin-3-gallate mitigates postovulatory oocyte aging by reducing oxidative stress and promoting embryonic development	11
Inflammatory response elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells	11
Exosomal or follicular FNDC3A decreases FOLR1 mRNA abundance and progesterone and lactate synthesis in bovine granulosa cells	11
A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum	11
Protamines: lessons learned from mouse models	11
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	10
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages	10
PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Postpartum mental health after medically complicated pregnancy	10
Omne vivum ex ovo: the oocyte reprogramming and remodeling activities	10
Current findings in endometrial microbiome: impact on uterine diseases	10
METTL3-mediated m6A modification promotes ferroptosis in adenomyosis through GPX4 in a YTHDF1-dependent manner	10
Hedgehog signalling in solitary motile cilia: detection and role of hedgehog factors in sperm functions and in vitro fertilization	10

Dysregulation of intracellular pH is a cause of impaired capacitation in Slc22a14-deficient mice	9
PP1γ1 is unable to substitute for the mammal-specific PP1γ2 isoform to support male fertility and sperm function	9
The interaction between seminal plasma, sperm, and endometrium in inter- and intra-species breeding in equids	9
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1	9
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	9
Changes to the reproductive microbiome of the brood pouch during male pregnancy in seahorses (Hippocampus abdominalis)	9
Single-cell multiomic analysis reveals methylome and transcriptome deviations following oocyte maturation in vitro	8
Gankyrin has a potential role in embryo implantation via activation of STAT3	8
Drosophila AK-3, a homolog of human CKMT1B, is essential for spermiogenesis	8
PCSK9 involves in the high-fat diet-induced abnormal testicular function of male mice	8
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	8
Exogenous melatonin ameliorates embryo–maternal cross-talk in early pregnancy in sheep	8
Sex, puberty, and the gut microbiome	8
Special series on reproductive health in transgender and gender-diverse patients	8
Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development	8
Reproductive Ageing: Current insights and a potential role of NAD in the reproductive health of aging fathers and their children	8
Cordycepin suppresses steroidogenic acute regulatory protein expression by reducing SP1 in human granulosa-lutein cells	8
Exosomes of mesenchymal stem cells and PRP restore spermatogenesis in the rat model of non-obstructive azoospermia	8
Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders	8
Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice	8
Male reproductive tract extracellular vesicles display region-specific heterogeneity in mice	8
Desert hedgehog mediates the proliferation of medaka spermatogonia through Smoothened signaling	8
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells	8
Identification of circular RNAs as regulators and noninvasive biomarkers for placenta accreta spectrum	8
The effect of vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function	8
Acknowledgement to reviewers	7
Elucidating metformin action on the ovary and fertility in healthy mice	7
The central role of pyruvate metabolism on the epigenetic maturation and transcriptional profile of bovine oocytes	7
Mitochondrial uncoupling proteins regulate the metabolic function of human Sertoli cells	7
SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor	7
Heterogeneous spectrum of CFTR gene mutations in Chinese patients with CAVD and the dilemma of genetic blocking strategy	7
Sperm utilize tumor necrosis factor alpha to shut down a 2-methoxyestradiol nongenomic pathway that accelerates oviductal egg transport in the rat	7
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: Gestational anti-Müllerian hormone and testosterone excess combined with maternal adiposity program for polycystic ovary syndrome	7
Pregnancy-specific glycoproteins: evolution, expression, functions and disease associations	7
Dysregulation of X-ray repair cross-complementing 4 expression in the eutopic endometrium of women with endometriosis	7
IGFBP7 enhances trophoblast invasion via IGF-1R/c-Jun signaling in unexplained recurrent spontaneous abortion	7
Nicotine exposure disrupts placental development via the Notch signaling pathway	7
Endometrial stromal cells from women with repeated implantation failure display impaired invasion towards trophoblastic spheroids	7
Increased plugging latency in cycling epiERα −/− (Esr1 f/− Wnt7a Cre/+ ) mice	7
The history of interferon-stimulated genes in pregnant cattle, sheep, and pigs	7
PREGNANCY DISORDERS AND MATERNAL CONSEQUENCES: Ethnic disparities in hypertensive disorders of pregnancy	7
Modulatory role of mTOR in trophoblast adaptive response in the early stage of placentation in sheep	7
Processes involved in prostaglandin F2alpha autoamplification in heifers	7
TRPM4 contribution in mouse uterine contractions	7