OOIR: Observatory of International Research

Papers

(The TQCC of Reproduction is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Differentiation of fetal sertoli cells in the adult testis	134
Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation	82
How, where and when is SPINK3 bound and removed from mouse sperm?	55
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway	53
Specc1l deficiency leads to abnormal oocyte meiosis and reduced blastocyst development in mouse	49
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa	45
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample	43
A proposed model of a clock that governs the length of human pregnancy	36
Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells	34
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	33
Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review	30
REPRODUCTIVE TOXICOLOGY: Environmental exposures, fetal testis development and function: phthalates and beyond	29
Fertility Treatment and Preservation Options for Transgender and Gender Diverse People	27
Environmental constraints and pathologies that modulate equine placental genes and development	27
A refined culture system of oocytes from early antral follicles promotes oocyte maturation and embryo development in cattle	26
Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome	24
High-lipid nutritional environment in different ontogenetic periods induce developmental programming of rat prostate at aging	24
Ca2+ concentrations in mouse sperm mitochondria fluctuate according to the cytosol	24
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation	23
Scientific contributions of Professor Sir Ian Wilmut	23
Vitamin D in follicular development and oocyte maturation	23
Superovulation-induced changes in murine ovarian perifollicular angiogenesis	22
Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause	22
Orphan nuclear receptors in angiogenesis and follicular development	21
CEP164 is essential for efferent duct multiciliogenesis and male fertility	20

Cell signaling in sperm midpiece ensures quiescence and survival in cauda epididymis	20
POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: The impact of polycystic ovary syndrome on reproductive health: a narrative review	20
A scoping review regarding reproductive capacity modulation based on alpha-ketoglutarate supplementation	19
Murine models of advanced maternal age: a systematic review and meta-analysis	19
Role of cAMP/PKA/CREB pathway and β-arrestin 1 in LH induced luteolysis in pregnant rats	19
Accessory corpus luteum regression during pregnancy II: reproductive outcomes	18
Two mouse lines selected for large litter size display different lifetime fecundities	18
The role of angiotensin II and relaxin in vascular adaptation to pregnancy	17
Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?	17
SPERM FACTORS AND EGG ACTIVATION: Fertilization failure after human ICSI and the clinical potential of PLCZ1	16
Telomeres and oocyte maturation rate are not reduced by COVID-19 except in severe cases	16
The effects of the activation of TLR2/TLR1 on in vitro angiogenesis in an immortalized ovine luteal endothelial cell line	16
Ultrastructural cilia defects in multi-ciliated uterine glandular epithelial cells from women with reproductive failure	16
Effect of in vitro growth on mouse oocyte competency, mitochondria and transcriptome	16
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques	16
Acbp is essential for decidualization during early pregnancy in mice	16
Glucose metabolism disorder related to follicular fluid exosomal miR-122-5p in cumulus cells of endometriosis patients	16
Progesterone stimulates histone citrullination to increase IGFBP1 expression in uterine cells	15
Gadd45g is required for timely Sry expression independently of RSPO1 activity	15
Urocortins exhibit differential effects on PGE2 and PGF2α output via CRHR2 in human myometrium	15
Novel PLCZ1 compound heterozygous mutations indicate gene dosage effect involved in total fertilisation failure after ICSI	15
Highly expressed lncRNA H19 in endometriosis promotes aerobic glycolysis and histone lactylation	14
Immunohistochemical examination of the uteroplacental interface of cows on days 21, 31, 40, and 67 of gestation	14
Cracking the enigma of adenomyosis: an update on its pathogenesis and pathophysiology	14
17β-Estradiol and cathepsins control primordial follicle growth in mouse ovaries	13
Molecular functions of Mrhl lncRNA in mouse spermatogenesis	13
Mechanisms of Adrenal Hyperandrogenism in Polycystic Ovary Syndrome	13
Novel insight into CD90 mesenchymal stem cell marker in mouse endometrial stroma during embryo implantation	13
DCAF13 and RNF114 participate in the regulation of early porcine embryo development	12
The reduction of oocytes and disruption of the meiotic prophase I in Fanconi anemia E-deficient mice	12
REPRODUCTIVE HEALTH IN TRANS AND GENDER DIVERSE PATIENTS: Mind the gap: a nationwide audit of LGBTQ+ inclusion in fertility care providers in the United Kingdom	12
The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesis	12
Pre-estrus progesterone does not affect post-estrus luminal metabolome in cross-bred beef cows	12
Pregnancy preparation: redistribution of CCR7-positive cells in the rat uterus	12
Extracellular vesicles improve embryo cryotolerance by maintaining the tight junction integrity during blastocoel re-expansion	12
Mechanisms of ovarian aging	11
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs	11
Disrupted MOS signaling alters meiotic cell cycle regulation and the egg transcriptome	11
Involvement of the Linker Histone H1Foo in the Regulation of Oogenesis	11
IMPACT OF REAL-LIFE ENVIRONMENTAL EXPROSURES ON REPRODUCTION: Adverse impacts of particulate matter air pollution on female and male reproduction	11
Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells	11
Inflammatory response elicited by Ureaplasma parvum colonization in human cervical epithelial, stromal, and immune cells	11
Protamines: lessons learned from mouse models	10
T2DM-elicited oxidative stress represses MTA3 expression in mouse Leydig cells	10
Characterization of ovarian progenitor cells for their potential to generate steroidogenic theca cells in vitro	10
A maternal ketogenic diet alters oviduct fluid nutrients and embryo histone acetylation in mice	10
SPERM FACTORS AND EGG ACTIVATION: PLCzeta as the sperm factor that activates eggs: 20 years on	10
Ovine fetal testis stage-specific sensitivity to environmental chemical mixtures	10
Exosomal or follicular FNDC3A decreases FOLR1 mRNA abundance and progesterone and lactate synthesis in bovine granulosa cells	10
miR-23b-3p regulates human endometrial epithelial cell adhesion implying a role in implantation	10

A primary effect of palmitic acid on mouse oocytes is the disruption of the structure of the endoplasmic reticulum	10
Investigating ticagrelor in a preclinical pipeline as a novel therapeutic to prevent preterm birth	10
Current findings in endometrial microbiome: impact on uterine diseases	9
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages	9
Metabolism-driven post-translational modifications of H3K9 in early bovine embryos	9
REPRODUCTIVE TOXICOLOGY: Pregnancy exposure to endocrine disrupting chemicals: implications for women’s health	9
Omne vivum ex ovo: the oocyte reprogramming and remodeling activities	9
The interaction between seminal plasma, sperm, and endometrium in inter- and intra-species breeding in equids	9
Reproductive Ageing: Declining translational capacity as a potential driver for oocyte meiotic instability	9
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1	9
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	9
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	8
Drosophila AK-3, a homolog of human CKMT1B, is essential for spermiogenesis	8
Reproductive Ageing: Current insights and a potential role of NAD in the reproductive health of aging fathers and their children	8
Changes to the reproductive microbiome of the brood pouch during male pregnancy in seahorses (Hippocampus abdominalis)	8
Identification of circular RNAs as regulators and noninvasive biomarkers for placenta accreta spectrum	8
PP1γ1 is unable to substitute for the mammal-specific PP1γ2 isoform to support male fertility and sperm function	8
Vascular biology of uterine fibroids: connecting fibroids and vascular disorders	8
Dysregulation of intracellular pH is a cause of impaired capacitation in Slc22a14-deficient mice	8
Cordycepin suppresses steroidogenic acute regulatory protein expression by reducing SP1 in human granulosa-lutein cells	8
Dolly at 25… is she ‘… still goin’ strong?’	8
Involvement of oxidative stress in placental dysfunction, the pathophysiology of fetal death and pregnancy disorders	8
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells	8
The effect of vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function	8
Hedgehog signalling in solitary motile cilia: detection and role of hedgehog factors in sperm functions and in vitro fertilization	8
The impact of antisperm antibodies on human male reproductive function: an update	8
Inhibition of HSP90AA1 induces abnormalities in bovine oocyte maturation and embryonic development	8
Exosomes of mesenchymal stem cells and PRP restore spermatogenesis in the rat model of non-obstructive azoospermia	8
Gankyrin has a potential role in embryo implantation via activation of STAT3	7
Plasma progesterone secretion during gestation of the captive short-beaked echidna	7
Exogenous melatonin ameliorates embryo–maternal cross-talk in early pregnancy in sheep	7
Processes involved in prostaglandin F2alpha autoamplification in heifers	7
Nicotine exposure disrupts placental development via the Notch signaling pathway	7
PCSK9 involves in the high-fat diet-induced abnormal testicular function of male mice	7
Sex, puberty, and the gut microbiome	7
Modulatory role of mTOR in trophoblast adaptive response in the early stage of placentation in sheep	7
SHP2 participates in decidualization by activating ERK to maintain normal nuclear localization of progesterone receptor	7
Special series on reproductive health in transgender and gender-diverse patients	7
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	7
Male reproductive tract extracellular vesicles display region-specific heterogeneity in mice	7
Desert hedgehog mediates the proliferation of medaka spermatogonia through Smoothened signaling	7
Role of the hypothalamus in ghrelin effects on reproduction: sperm function and sexual behavior in male mice	7
TRPM4 contribution in mouse uterine contractions	7