OOIR: Observatory of International Research

Papers

(The TQCC of Reproduction is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
The CASR antagonist NPS2143 induces loss of acrosomal integrity and proteolysis of SPACA1 in boar spermatozoa	123
REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Psychosocial counseling of transgender and gender-diverse individuals in fertility and reproductive medicine: a narrative review	73
Investigation of infertility using endometrial organoids	50
CRISPR/Cas13d-mediated efficient KDM5B mRNA knockdown in porcine somatic cells and parthenogenetic embryos	46
Reproductive Health in Trans and Gender Diverse Patients: Fertility related knowledge, attitudes, and decision-making among gender diverse youth – A narrative review	45
Specc1l deficiency leads to abnormal oocyte meiosis and reduced blastocyst development in mouse	41
How, where and when is SPINK3 bound and removed from mouse sperm?	35
Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation	32
Xenograft model of heterotopic transplantation of human ovarian cortical tissue and its clinical relevance	28
Expression and role of resistin on steroid secretion in the porcine corpus luteum	27
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception	26
Prenatal cadmium exposure has inter-generational adverse effects on Sertoli cells through the follicle-stimulating hormone receptor pathway	26
FSH promotes immature porcine Sertoli cell proliferation by activating the CCR7/Ras-ERK signaling axis	24
IFNT stimulates lysosomal function via type I IFN signaling pathway in pregnant bovine leukocytes	23
Gene editing to investigate the role of conceptus factors in the establishment of pregnancy in the pig	23
A long non-coding RNA essential for early embryonic development improves somatic cell nuclear transfer somatic cell nuclear transfer efficiency in goats	23
Does single-strand DNA break repair capacity influence oocyte maintenance and quality?	22
Omne vivum ex ovo: the oocyte reprogramming and remodeling activities	22
Formation of fibrin at sites of conceptus adhesion in the ewe	21
REPRODUCTIVE TOXICOLOGY: The male mammary gland: a novel target of endocrine-disrupting chemicals	21
Maternal age, obesity and hyperglycaemia are associated with a delay in preimplantation embryo development in mouse	21
The interaction between seminal plasma, sperm, and endometrium in inter- and intra-species breeding in equids	20
Metabolism-driven post-translational modifications of H3K9 in early bovine embryos	20
Creatine promotes endometriosis progression by inducing M2 polarization of peritoneal macrophages	19
Visfatin increases the invasive potential of ovarian granulosa tumor spheroids by reprogramming glucose metabolism	19

REPRODUCTIVE TOXICOLOGY: Reproductive toxicology: emerging toxicants and cellular targets	19
Recombinant FSH induced progesterone via partially regulating let-7 expression in human and mouse granulosa cells	19
Differentiation of fetal sertoli cells in the adult testis	19
An attempt to search for the common cellular mechanism of ovulation across all metazoans	18
Early ovarian differentiation in the tammar wallaby and the effects of exposure to bisphenol A	18
Naked mole rat ovaries allow investigation of ovarian reserve, in vitro germ cell expansion, and oocyte in vitro maturation within a single sample	18
dmrtb1 is involved in the testicular development in Larimichthys crocea	17
YAP1 and WWTR1 are required for murine pregnancy initiation	17
Progesterone induces porcine sperm release from oviduct glycans in a proteasome-dependent manner	16
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa	16
SPERM FACTORS AND EGG ACTIVATION: The structure and function relationship of sperm PLCZ1	15
REPRODUCTIVE TOXICOLOGY: Environmental exposures, fetal testis development and function: phthalates and beyond	15
Equine maternal aging affects oocyte lipid content, metabolic function and developmental potential	15
WISP2/IGF1 promotes the survival of DSCs and impairs the cytotoxicity of decidual NK cells	15
Differences in human placental mesenchymal stromal cells may impair vascular function in FGR	15
Manipulating bovine granulosa cell energy metabolism limits inflammation	15
The role of steroidogenic factor 1 (SF-1) in steroidogenic cell function of the testes and ovaries of mature mice	14
The impact of cannabiniods on reproductive function	14
ZNF146 regulates cell cycle progression via TFDP1 and DEPDC1B in ovarian cancer cells	14
Investigations into the role of platelet-activating factor in the peri-conception period of the mare	13
Immunomodulation for unexplained recurrent implantation failure: where are we now?	13
Genesis of clinical and subclinical endometritis in dairy cows	13
A proposed model of a clock that governs the length of human pregnancy	13
Emodin improves glucose metabolism and ovarian function in PCOS mice via the HMGB1/TLR4/NF-κB molecular pathway	13
Melatonin ameliorates ovarian dysfunction by regulating autophagy in PCOS via the PI3K-Akt pathway	12
Hypoxia-mediated chemotaxis and residence of macrophage in decidua by secreting VEGFA and CCL2 during normal pregnancy	12
REPRODUCTIVE TOXICOLOGY: Pregnancy exposure to endocrine disrupting chemicals: implications for women’s health	12
I W Rowlands, Barbara J Weir and the biology of the hystricomorph rodents	12
A field guide to Aurora kinase inhibitors: an oocyte perspective	12
NPR3 is regulated by gonadotropins and modulates bovine cumulus cell expansion	12
Vascular biology of uterine fibroids: connecting fibroids and vascular disorders	11
Involvement of chemerin and CMKLR1 in the progesterone decrease by PCOS granulosa cells	11
The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis	11
Development of polarity-reversed endometrial epithelial organoids	11
Finasteride interferes with prostaglandin-induced CatSper signalling in human sperm	11
Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling	11
Progesterone supplementation after postovulatory mifepristone reduce changes in human endometrial gene expression	11
TEAD4 regulates KRT8 and YAP in preimplantation embryos in mice but not in cattle	11
New allele of mouse DNA/RNA helicase senataxin causes meiotic arrest and infertility	11
Oviduct and endometrial epithelium improve in vitro produced bovine embryo developmental kinetics	11
Decoding bull fertility in vitro: a proteomics exploration from sperm to blastocyst	10
Mesenchymal stem cell secretome alters gene expression and upregulates motility of human endometrial stromal cells	10
The kisspeptin analog C6 reverses reproductive dysfunction in a mouse model of hyperprolactinemia	10
Elevated expression and reduced phosphorylation of uterine RIG-I protein in a murine model of pathogenic preterm labor	10
A lack of commensal microbiota influences the male reproductive tract intergenerationally in mice	10
The impact of antisperm antibodies on human male reproductive function: an update	9
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG	9
Placental adaptation to maternal malnutrition	9
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Reactive oxygen species in the mammalian pre-implantation embryo	9
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Oxidative stress in polycystic ovary syndrome	9

BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells	9
OONO–/MMP2/MMP9 pathway-mediated apoptosis of porcine granulosa cells is associated with DNA damage	9
OXIDATIVE STRESS AND REPRODUCTIVE FUNCTION: Sperm telomeres, oxidative stress, and infertility	9
Pendimethalin exposure disrupts mitochondrial function and impairs processes related to implantation	8
Cordycepin suppresses steroidogenic acute regulatory protein expression by reducing SP1 in human granulosa-lutein cells	8
Homeostatic regulation of lipid droplet content in mammalian oocytes and embryos	8
The effect of vitamin D (1,25-(OH)2-D3) on human theca and granulosa cell function	8
Irisin decreases follicle development in cattle and inhibits theca cell steroidogenesis through focal adhesion kinase signaling	8
Synthetic embryos: a new venue in ethical research	8
REPRODUCTIVE TOXICOLOGY: Impact of endocrine disruptors on neurons expressing GnRH or kisspeptin and pituitary gonadotropins	8
MEK signalling pathway is required for hypoblast specification and migration in ovine	8
Sex, puberty, and the gut microbiome	8
IGF2BP1 stabilizes Akt2 mRNA to promote glucose metabolism and maintain spermatogonial proliferation	8
Decreased level of Eomes+dCD8+ T cells with altered function might be associated with miscarriage	8
TORC2/3-mediated DUSP1 upregulation is essential for human decidualization	8
Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause	8
Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads	8
Changes to the reproductive microbiome of the brood pouch during male pregnancy in seahorses (Hippocampus abdominalis)	8
Sire modulates developmental kinetics and transcriptome of the bovine embryo	8
Cells responding to hedgehog signaling contribute to the theca of ovarian follicles	7
Culture of vitrified bovine ovarian tissue on agarose gel inserts maintains follicle integrity	7
The concentration of glucose in the media influences the susceptibility of stallion spermatozoa to ferroptosis	7
Decreased NSD2 impairs stromal cell proliferation in human endometrium via reprogramming H3K36me2	7
Twenty-five years after Dolly – How far have we come?	7
Causative mechanisms and functional correlates of MTT reduction in stallion spermatozoa	7
High-lipid nutritional environment in different ontogenetic periods induce developmental programming of rat prostate at aging	7
L-Carnitine sustainably affects bioenergetic profile of bovine blastocysts and transcriptome profile of elongation-stage embryos	7
Whole-genome DNA methylation analysis of the sperm in relation to bull fertility	7
NR2C2 of macrophages promotes inflammation via NF-κB in LPS-induced orchitis in mice	7
Negative effects of endocrine disruptor bisphenol A on ovarian granulosa cells and the protective role of folic acid	7
Endoplasmic reticulum stress promotes endometrial fibrosis through the TGF-β/SMAD pathway	7
Dysregulation of intracellular pH is a cause of impaired capacitation in Slc22a14-deficient mice	7
Zinc as a non-hormonal contraceptive: an alternative to the copper intrauterine device (IUD)	7
The dogma of the sterile uterus revisited: does microbial seeding occur during fetal life in humans and animals?	7
Oocyte activation is a cytoplasm-confined event so far: what about the nucleus?	7
Plasma progesterone secretion during gestation of the captive short-beaked echidna	7
Dolly at 25… is she ‘… still goin’ strong?’	7
Coumestrol induces oxidative stress and impairs migration and embryonic growth	7
Inhibition of MTOR signaling impairs rat embryo organogenesis by affecting folate availability	6
Dual role of valosin-containing protein (VCP/p97) in mouse sperm during capacitation	6
TRIM28 maintains genome imprints and regulates development of porcine SCNT embryos	6
Scientific contributions of Professor Sir Ian Wilmut	6
Markers of equine placental differentiation: insights from gene expression studies	6
Maternal exposure to an enriched environment promotes uterine vascular remodeling and prevents embryo loss in mice	6
O-GlcNAc participates in the meiosis of aging oocytes by mediating mitochondrial function	6
Stem cell-conditioned medium improves methylation patterns and quality of caprine preantral follicles	6
Ca2+ concentrations in mouse sperm mitochondria fluctuate according to the cytosol	6
Characterization of bioenergetic and kinematic plasticity of bovine sperm reveals novel and dynamic temporal traits	6
Fish sperm cryopreservation using biodegradable containers: New low-cost and environment-friendly methodology	6
Maternal restricted- and over- feeding during gestation perturb offspring sperm epigenome in sheep	6
Genistein ameliorates starvation-induced porcine follicular granulosa cell apoptosis	6
Testosterone regulation on quiescin sulfhydryl oxidase 2 synthesis in the epididymis	6
Hypoxia-induced autophagy inhibits myometrial proliferation in pregnant mice via the mTOR pathway in vitro	6
GRSF1 deficiency attenuates mitochondrial function in aging granulosa cells	6
Atrazine disorganises laminin formation and reduces cell numbers in the tammar testis during early differentiation	6
SPERM FACTORS AND EGG ACTIVATION: Phospholipase C zeta (PLCZ1) and the clinical diagnosis of oocyte activation deficiency	6
PP1γ1 is unable to substitute for the mammal-specific PP1γ2 isoform to support male fertility and sperm function	6
High-throughput phenotypic screening of the human spermatozoon	6
Peptidylarginine deiminase 2 regulates expression of DGCR8 affecting miRNA biogenesis in gonadotrope cells	6
Is seminal nerve growth factor-induced luteinizing hormone release in camelids mediated at the hypothalamus?	6
REPRODUCTIVE HEALTH IN TRANS AND GENDER-DIVERSE PATIENTS: Trauma-informed reproductive care for transgender and nonbinary people	6
Spermatogonial depletion and a spermatogenesis defect in the Dp(16)1Yey mouse model of Down syndrome	6