OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Reviews Molecular Cell Biology is 95. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
When senescence generates pluripotent stem cells	2472
The translation m(o)TOR that propels regeneration	1497
Re-sizing of nuclear pores	1444
Transfection reflections: fit-for-purpose delivery of nucleic acids	1197
From trans-splicing discovery and onwards, trypanosomes lead the way	899
A dynamic culture system that models the intricacy of the mammary gland	895
DNA-repair-driven cell death compels us to rethink cancer therapies	860
Tightening the epithelium to control signalling	687
Histone H1 deamidation regulates DNA double-strand break repair	657
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways	634
Mechanisms of substrate processing during ER-associated protein degradation	633
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids	627
Understanding mechanisms of antioxidant action in health and disease	611
Modulation of cellular processes by histone and non-histone protein acetylation	574
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment	471
Decoding the Ca2+ signal for salt tolerance	466
The double life of a transcription factor in the cytoplasm	461
Chemical reprogramming of human blood cells	415
Publisher Correction: Plant hormone regulation of abiotic stress responses	402
Resilience through selective translation	386
How proteins sense their cellular environment	377
The phosphoinositide PI5P inhibits the Hippo pathway effector YAP	377
New insights into activation and function of the AMPK	376
N-glycan-dependent protein maturation and quality control in the ER	372
Mechanism and regulation of kinesin motors	371

The advent of confocal laser scanning microscopy in biological research	351
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance	350
The emerging mechanisms and functions of microautophagy	342
C-degron mimicry confers E3 ligase selectivity	331
The healing role of gasdermin B in IBD	331
Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation	330
Nucleosomes as blueprints of genome architecture	322
Studying lysosomal function and dysfunction using LysoIP	321
Bookmarking pluripotency genes	318
Silencing centromeres with age	304
The discovery of oncogene-induced senescence	303
Coordination of cardiogenesis in vivo and in vitro	290
Telomere function and regulation from mouse models to human ageing and disease	289
Mechanisms and roles of podosomes and invadopodia	274
Regulation, functions and transmission of bivalent chromatin during mammalian development	272
Biology and therapeutic targeting of vascular endothelial growth factor A	271
CRISPR–Cas applications in agriculture and plant research	259
Regulation of membrane protein structure and function by their lipid nano-environment	249
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design	235
Curvature-mediated endocytosis	234
Big cells, small potential	230
Molecular tools for analysing in vivo senescence	221
A quick guide to (transmembrane) planar cell polarity mouse strains	221
Publisher Correction: Emerging roles and functional mechanisms of PIWI- interacting RNAs	214
Improving chemical reprogramming strategies	199
Migrasomes promote angiogenesis	198
Science Twitter — navigating change in science communication	195
Snoozing APC/C for a sweet cell cycle entry	193
A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals	191
The RNA world ‘hypothesis’	190
A histone variant that manages abiotic stress in plants	189
Circadian clock communication during homeostasis and ageing	188
Splicing regulation through biomolecular condensates and membraneless organelles	185
The prospects and opportunities of protein structure prediction with AI	180
Why novel mRNA modifications are so challenging and what we can do about it	177
Context-dependent TGFβ family signalling in cell fate regulation	169
FOXO transcription factors as mediators of stress adaptation	167
Molecular mechanisms and consequences of mitochondrial permeability transition	163
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens	163
Transposons: catch them if you can	161
New tool for MAPping microtubule dynamics	159
RNA binding — a useful third wheel in transcription	158
Energy-driven genome regulation by ATP-dependent chromatin remodellers	154
Context-specific regulation and function of mRNA alternative polyadenylation	144
Activation of human endogenous retroviruses and its physiological consequences	141
Mechanisms of mitochondrial respiratory adaptation	140
Does species-specific alternative splicing make us human?	135
Regulation and function of insulin and insulin-like growth factor receptor signalling	131
Transcriptional control of energy metabolism by nuclear receptors	131
How ancient RNA survives and what we can learn from it	131

Integrated biophysical imaging of cell interactions with 3D extracellular matrices	131
Revisiting small RNA movement in plants	129
Molecular machineries and pathways of mitochondrial protein transport	128
Apical–basal polarity and the control of epithelial form and function	127
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases	121
A guide to cell death pathways	119
Targeted protein degradation: from mechanisms to clinic	113
Myosin VI assists in fork protection	110
New frontiers in quality control: the case of GPI-anchored proteins	110
Cold-induced longevity through proteasome boosting	110
The centromere as a tag of self-DNA	106
Author Correction: All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies	105
Redox-driven cell death by disulfidptosis and its therapeutic potential	100
Resolution in super-resolution microscopy — definition, trade-offs and perspectives	99
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex	99
The molecular basis for cellular function of intrinsically disordered protein regions	98
The technological landscape and applications of single-cell multi-omics	96
Polarized endoplasmic reticulum–plasma membrane contacts in cell migration	95
ATP and ROS signal cell extrusion	95
DEI conversations: more than a box-ticking exercise	95
Fat cells have long-lasting (epigenetic) memory	95