OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Reviews Molecular Cell Biology is 94. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
When senescence generates pluripotent stem cells	2019
The translation m(o)TOR that propels regeneration	1941
Tightening the epithelium to control signalling	1207
Histone H1 deamidation regulates DNA double-strand break repair	1193
The secretory pathway gets a molecular framework	1147
A dynamic culture system that models the intricacy of the mammary gland	1063
Transfection reflections: fit-for-purpose delivery of nucleic acids	878
DNA-repair-driven cell death compels us to rethink cancer therapies	863
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways	838
Understanding mechanisms of antioxidant action in health and disease	722
Advancing single-cell omics and cell-based therapeutics with quantum computing	644
Mechanisms of substrate processing during ER-associated protein degradation	643
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment	625
Decoding the Ca2+ signal for salt tolerance	617
The double life of a transcription factor in the cytoplasm	612
Chemical reprogramming of human blood cells	554
Resilience through selective translation	503
Mechanism and regulation of kinesin motors	491
Engineered nanobodies facilitate cryo-EM studies of small proteins	487
The advent of confocal laser scanning microscopy in biological research	487
Progress in stem cell-based embryo models and their applications in developmental biology and biomedicine	486
The phosphoinositide PI5P inhibits the Hippo pathway effector YAP	466
How proteins sense their cellular environment	435
PIONEARing how DNA sequence composition tunes TF–nucleosome interactions	435
Programmed ‘DNA splicing’ removes transposons from genes	414

N-glycan-dependent protein maturation and quality control in the ER	396
The emerging mechanisms and functions of microautophagy	390
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance	369
Publisher Correction: Plant hormone regulation of abiotic stress responses	365
New insights into activation and function of the AMPK	331
C-degron mimicry confers E3 ligase selectivity	329
Nucleosomes as blueprints of genome architecture	318
Silencing centromeres with age	315
Bookmarking pluripotency genes	303
Coordination of cardiogenesis in vivo and in vitro	293
DNA looping regulates transcription	288
Studying lysosomal function and dysfunction using LysoIP	283
Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation	282
ESCRT-III function in membrane fission and repair	281
Telomere function and regulation from mouse models to human ageing and disease	275
The discovery of oncogene-induced senescence	267
CRISPR–Cas applications in agriculture and plant research	256
Biology and therapeutic potential of extracellular vesicle targeting and uptake	256
Regulation of membrane protein structure and function by their lipid nano-environment	253
Biology and therapeutic targeting of vascular endothelial growth factor A	250
Mechanisms and roles of podosomes and invadopodia	246
Regulation, functions and transmission of bivalent chromatin during mammalian development	241
Curvature-mediated endocytosis	230
Molecular tools for analysing in vivo senescence	225
A quick guide to (transmembrane) planar cell polarity mouse strains	219
Snoozing APC/C for a sweet cell cycle entry	213
A histone variant that manages abiotic stress in plants	212
Publisher Correction: Emerging roles and functional mechanisms of PIWI- interacting RNAs	211
Science Twitter — navigating change in science communication	211
Migrasomes promote angiogenesis	200
The RNA world ‘hypothesis’	200
Improving chemical reprogramming strategies	193
FOXO transcription factors as mediators of stress adaptation	189
Context-dependent TGFβ family signalling in cell fate regulation	187
A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals	180
Splicing regulation through biomolecular condensates and membraneless organelles	178
Circadian clock communication during homeostasis and ageing	173
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens	171
Like water on rock, the microenvironment bends stem cell fate	164
RNA binding — a useful third wheel in transcription	164
Mechanisms and regulation of the Hsp70 chaperone network	162
Energy-driven genome regulation by ATP-dependent chromatin remodellers	162
Subcellular localization as a driver of protein function	162
Activation of human endogenous retroviruses and its physiological consequences	161
Context-specific regulation and function of mRNA alternative polyadenylation	160
Mechanisms of mitochondrial respiratory adaptation	156
Does species-specific alternative splicing make us human?	151
Integrated biophysical imaging of cell interactions with 3D extracellular matrices	147
Organelles stick together through PDZD8-mediated condensate formation	143
How ancient RNA survives and what we can learn from it	140

A guide to cell death pathways	133
Transcriptional control of energy metabolism by nuclear receptors	133
Regulation and function of insulin and insulin-like growth factor receptor signalling	129
Molecular machineries and pathways of mitochondrial protein transport	128
Targeted protein degradation: from mechanisms to clinic	126
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases	122
Myosin VI assists in fork protection	122
The centromere as a tag of self-DNA	121
Cold-induced longevity through proteasome boosting	118
Author Correction: All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies	116
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex	115
New frontiers in quality control: the case of GPI-anchored proteins	110
Decoding ubiquitin signals inside cells	109
Resolution in super-resolution microscopy — definition, trade-offs and perspectives	105
The molecular basis for cellular function of intrinsically disordered protein regions	103
Redox-driven cell death by disulfidptosis and its therapeutic potential	100
The technological landscape and applications of single-cell multi-omics	96
Microenvironmental determinants of endothelial cell heterogeneity	96
DEI conversations: more than a box-ticking exercise	96
Author Correction: Regulation of membrane protein structure and function by their lipid nano-environment	94