Nature Reviews Molecular Cell Biology

Papers
(The TQCC of Nature Reviews Molecular Cell Biology is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-07-01 to 2025-07-01.)
ArticleCitations
The translation m(o)TOR that propels regeneration2342
When senescence generates pluripotent stem cells1281
Tightening the epithelium to control signalling1255
Transfection reflections: fit-for-purpose delivery of nucleic acids1249
A dynamic culture system that models the intricacy of the mammary gland1056
From trans-splicing discovery and onwards, trypanosomes lead the way986
Re-sizing of nuclear pores776
Histone H1 deamidation regulates DNA double-strand break repair774
Pore-forming proteins as drivers of membrane permeabilization in cell death pathways754
Sources, resolution and physiological relevance of R-loops and RNA–DNA hybrids599
Mechanisms of substrate processing during ER-associated protein degradation594
The aetiology and molecular landscape of insulin resistance549
Understanding mechanisms of antioxidant action in health and disease528
Modulation of cellular processes by histone and non-histone protein acetylation518
Exploiting cell cycle-dependent dephosphorylation for mitosis-specific protein recruitment490
Publisher Correction: Plant hormone regulation of abiotic stress responses433
Resilience through selective translation421
How proteins sense their cellular environment398
The phosphoinositide PI5P inhibits the Hippo pathway effector YAP398
N-glycan-dependent protein maturation and quality control in the ER387
Decoding the Ca2+ signal for salt tolerance375
Mechanism and regulation of kinesin motors372
The emerging mechanisms and functions of microautophagy356
New insights into activation and function of the AMPK342
Establishment of H3K9-methylated heterochromatin and its functions in tissue differentiation and maintenance341
The healing role of gasdermin B in IBD338
Rise and SINE: roles of transcription factors and retrotransposons in zygotic genome activation333
CRISPR–Cas applications in agriculture and plant research332
C-degron mimicry confers E3 ligase selectivity331
Bookmarking pluripotency genes318
Silencing centromeres with age318
Voices of the new generation: open science is good for science (and for you)304
The discovery of oncogene-induced senescence299
Regulation, functions and transmission of bivalent chromatin during mammalian development298
Telomere function and regulation from mouse models to human ageing and disease294
Nucleosomes as blueprints of genome architecture291
Biology and therapeutic targeting of vascular endothelial growth factor A289
Studying lysosomal function and dysfunction using LysoIP284
Mechanisms and roles of podosomes and invadopodia276
Regulation of membrane protein structure and function by their lipid nano-environment275
Curvature-mediated endocytosis274
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design274
Big cells, small potential268
Publisher Correction: Emerging roles and functional mechanisms of PIWI- interacting RNAs249
Molecular tools for analysing in vivo senescence245
A quick guide to (transmembrane) planar cell polarity mouse strains236
Science Twitter — navigating change in science communication233
Migrasomes promote angiogenesis225
Improving chemical reprogramming strategies207
Why novel mRNA modifications are so challenging and what we can do about it205
The prospects and opportunities of protein structure prediction with AI205
The RNA world ‘hypothesis’203
Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens200
Context-dependent TGFβ family signalling in cell fate regulation197
Splicing regulation through biomolecular condensates and membraneless organelles195
Circadian clock communication during homeostasis and ageing194
A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals193
Molecular mechanisms and consequences of mitochondrial permeability transition193
FOXO transcription factors as mediators of stress adaptation192
Machinery, regulation and pathophysiological implications of autophagosome maturation183
Transposons: catch them if you can176
RNA binding — a useful third wheel in transcription168
New tool for MAPping microtubule dynamics167
Energy-driven genome regulation by ATP-dependent chromatin remodellers166
Activation of human endogenous retroviruses and its physiological consequences161
Context-specific regulation and function of mRNA alternative polyadenylation158
Mechanisms of mitochondrial respiratory adaptation158
Does species-specific alternative splicing make us human?157
Integrated biophysical imaging of cell interactions with 3D extracellular matrices153
Regulation and function of insulin and insulin-like growth factor receptor signalling147
Apical–basal polarity and the control of epithelial form and function144
Mechanisms of autophagy–lysosome dysfunction in neurodegenerative diseases141
How ancient RNA survives and what we can learn from it139
Targeted protein degradation: from mechanisms to clinic138
Transcriptional control of energy metabolism by nuclear receptors135
Revisiting small RNA movement in plants133
A guide to cell death pathways129
Myosin VI assists in fork protection127
Cold-induced longevity through proteasome boosting127
New frontiers in quality control: the case of GPI-anchored proteins126
The centromere as a tag of self-DNA125
Author Correction: All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies125
Genomic regulation of transcription and RNA processing by the multitasking Integrator complex124
Resolution in super-resolution microscopy — definition, trade-offs and perspectives121
The molecular basis for cellular function of intrinsically disordered protein regions120
The technological landscape and applications of single-cell multi-omics116
DEI conversations: more than a box-ticking exercise115
Polarized endoplasmic reticulum–plasma membrane contacts in cell migration114
Fat cells have long-lasting (epigenetic) memory110
Genome characteristics at the borders105
ATP and ROS signal cell extrusion102
Anticancer effects of zotatifin are mediated by RNA structure remodelling101
Author Correction: Regulation of membrane protein structure and function by their lipid nano-environment97
Microenvironmental determinants of endothelial cell heterogeneity92
Author Correction: Guidelines and definitions for research on epithelial–mesenchymal transition89
Author Correction: Fibroblast and myofibroblast activation in normal tissue repair and fibrosis89
Deep learning shapes single-cell data analysis88
Nuclear compartmentalization as a mechanism of quantitative control of gene expression88
Regulation of phospholipid distribution in the lipid bilayer by flippases and scramblases87
Interplay between mechanics and signalling in regulating cell fate86
The role and regulation of integrins in cell migration and invasion82
Roles of RIPK1 as a stress sentinel coordinating cell survival and immunogenic cell death80
Ethylene — the lifeguard hormone80
Mechanisms of microtubule organization in differentiated animal cells80
Sleep tight thanks to Parp180
Author Correction: Mechanisms of lncRNA biogenesis as revealed by nascent transcriptomics79
Unravelling oocyte ultrastructure76
Voices of the new generation: importance of emotional ‘match’ in mentoring relationships75
From shortening telomeres to replicative crisis73
The contribution of databases towards understanding the universe of long non-coding RNAs71
Transcription factors crossing the cell membrane70
Profiling the disordered proteome in cells using a chemical tag69
The many regulators of epithelial−mesenchymal transition66
The molecular principles of gene regulation by Polycomb repressive complexes65
Reassessing the relationship between mRNA levels and protein abundance in exercised skeletal muscles65
How green is your science? The race to make laboratories sustainable65
All the sites we cannot see: Sources and mitigation of false negatives in RNA modification studies64
Karyopherin-mediated nucleocytoplasmic transport62
Exercise metabolism and adaptation in skeletal muscle60
Fibroblast and myofibroblast activation in normal tissue repair and fibrosis59
Mechanisms and regulation of substrate degradation by the 26S proteasome57
Mechanisms of SARS-CoV-2 entry into cells57
0.045696020126343