BMC Bioinformatics

Papers
(The H4-Index of BMC Bioinformatics is 43. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Nonnegative matrix factorization analysis and multiple machine learning methods identified IL17C and ACOXL as novel diagnostic biomarkers for atherosclerosis1455
A novel nonparametric computational strategy for identifying differential methylation regions1046
REDalign: accurate RNA structural alignment using residual encoder-decoder network300
Linear programming based gene expression model (LPM-GEM) predicts the carbon source for Bacillus subtilis246
Employing phylogenetic tree shape statistics to resolve the underlying host population structure198
Predictive modeling of gene expression regulation148
Grace-AKO: a novel and stable knockoff filter for variable selection incorporating gene network structures130
SALON ontology for the formal description of sequence alignments103
Locality-sensitive hashing enables efficient and scalable signal classification in high-throughput mass spectrometry raw data93
Abstraction-based segmental simulation of reaction networks using adaptive memoization84
Multivariate estimation of factor structures of complex traits using SNP-based genomic relationships83
Correction to: Avian Immunome DB: an example of a user‑friendly interface for extracting genetic information77
airpg: automatically accessing the inverted repeats of archived plastid genomes77
A drug repositioning algorithm based on a deep autoencoder and adaptive fusion76
Graph regularized non-negative matrix factorization with prior knowledge consistency constraint for drug–target interactions prediction73
Mathematical modelling of SigE regulatory network reveals new insights into bistability of mycobacterial stress response70
Topology preserving stratification of tissue neoplasticity using Deep Neural Maps and microRNA signatures68
Correction: DeepSuccinylSite: a deep learning based approach for protein succinylation site prediction67
Not seeing the trees for the forest. The impact of neighbours on graph-based configurations in histopathology65
CoQUAD: a COVID-19 question answering dataset system, facilitating research, benchmarking, and practice62
CMIC: predicting DNA methylation inheritance of CpG islands with embedding vectors of variable-length k-mers60
Exploring cell-specific miRNA regulation with single-cell miRNA-mRNA co-sequencing data59
Prediction of hot spots in protein–DNA binding interfaces based on discrete wavelet transform and wavelet packet transform59
Integrated analysis of the voltage-gated potassium channel-associated gene KCNH2 across cancers57
PEPMatch: a tool to identify short peptide sequence matches in large sets of proteins55
HPC-T-Assembly: a pipeline for de novo transcriptome assembly of large multi-specie datasets54
A binary biclustering algorithm based on the adjacency difference matrix for gene expression data analysis53
Multilayer network alignment based on topological assessment via embeddings52
StackTTCA: a stacking ensemble learning-based framework for accurate and high-throughput identification of tumor T cell antigens52
Combining denoising of RNA-seq data and flux balance analysis for cluster analysis of single cells51
Hitac: a hierarchical taxonomic classifier for fungal ITS sequences compatible with QIIME250
CircWalk: a novel approach to predict CircRNA-disease association based on heterogeneous network representation learning50
rKOMICS: an R package for processing mitochondrial minicircle assemblies in population-scale genome projects50
Enabling personalised disease diagnosis by combining a patient’s time-specific gene expression profile with a biomedical knowledge base50
Latent dirichlet allocation for double clustering (LDA-DC): discovering patients phenotypes and cell populations within a single Bayesian framework49
A gene based combination test using GWAS summary data47
LDAGM: prediction lncRNA-disease asociations by graph convolutional auto-encoder and multilayer perceptron based on multi-view heterogeneous networks47
Examination of blood samples using deep learning and mobile microscopy46
SumStatsRehab: an efficient algorithm for GWAS summary statistics assessment and restoration46
Prediction of HIV-1 protease cleavage site from octapeptide sequence information using selected classifiers and hybrid descriptors45
Empowering the discovery of novel target-disease associations via machine learning approaches in the open targets platform45
Mabs, a suite of tools for gene-informed genome assembly44
From a genome assembly to full regulatory network prediction: the case study of Rhodotorula toruloides putative Haa1-regulon44
Combining whole genome sequencing and non-adaptive group testing for large-scale ethnicity screens43
SVDNVLDA: predicting lncRNA-disease associations by Singular Value Decomposition and node2vec43
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