OOIR: Observatory of International Research

Papers

(The median citation count of BMC Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Integrated bulk RNA sequencing and mass cytometry analysis reveal the circulating immune landscape in ischemic and hemorrhagic Moyamoya disease	57
Bacille Calmette-Guérin-specific IgG titres among infants born to mothers with active tuberculosis disease in Uganda	42
Gut microbiota regulation of T lymphocyte subsets during systemic lupus erythematosus	28
Naïve CD4+ cell counts significantly decay and high HIV RNA levels contribute to immunological progression in long-term non-progressors infected with HIV by blood products: a cohort study	26
Cisplatin-based chemoradiation decreases telomerase-specific CD4 TH1 response but increases immune suppressive cells in peripheral blood	24
Type 2 innate lymphoid cells from Id1 transgenic mice alleviate skin manifestations of graft-versus-host disease	22
Reversing BCG-mediated autophagy inhibition and mycobacterial survival to improve vaccine efficacy	20
Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15	18
A longitudinal study of humoral immune responses induced by a 3-dose inactivated COVID-19 vaccine in an observational, prospective cohort	18
Low-dose interleukin-2 can improve salivary secretion but not lymphocyte infiltration of salivary glands in a murine model of Sjögren’s syndrome	18
Investigation of KIR/HLA relationship and other clinical variables after T-cell-replete haploidentical bone marrow transplantation in patients with acute myeloid leukemia (AML)	18
Phenotypic and immune functional profiling of patients with suspected Mendelian Susceptibility to Mycobacterial Disease in South Africa	17
Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort	16
Increased serum adenosine deaminase activity in patients with adult-onset Still's disease	15
Pharmacokinetic interaction assessment of an HIV broadly neutralizing monoclonal antibody VRC07-523LS: a cross-protocol analysis of three phase 1 trials in people without HIV	15
Effect of immune-modulating metronomic capecitabine as an adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma	15
Comprehensive evaluation of the effects of long-term cryopreservation on peripheral blood mononuclear cells using flow cytometry	15
Seroconversion rates following 2 doses of measles- mumps- rubella vaccination given at the ages 12 and 18 months: data for possible additional dose at older age	14
GNUV201, a novel human/mouse cross-reactive and low pH-selective anti-PD-1 monoclonal antibody for cancer immunotherapy	14
Immunomodulatory effects of β-defensin 2 on macrophages induced immuno-upregulation and their antitumor function in breast cancer	13
Function and autophagy of monocyte-derived dendritic cells is affected by hepatitis B virus infection	13
Clinical relevance of glomerular IgM deposition in patients with lupus nephritis	13
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication	12
Comparison of novel native probiotics and paraprobiotics in modulating oxidative stress and inflammation in DSS-induced colitis: implications for enhanced therapeutic strategies in high fat diet	12
Increased infiltration of CD4+ T cell in the complement deficient lymphedema model	12

Transcriptomic evidence for atopic dermatitis as a systemic disease in NC/Nga mice	12
The diagnostic value and validation of IL-22 combined with sCD40L in tuberculosis pleural effusion	11
Lack of autoantibodies against collagen and related proteins in collagenous colitis	11
Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model	11
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation	11
High glucose condition aggravates inflammatory response induced by Porphyromonas gingivalis in THP-1 macrophages via autophagy inhibition	11
Vitamin D and biomarkers of inflammation and oxidative stress among pregnant women: a systematic review of observational studies	11
Higher plasma interleukin − 6 levels are associated with lung cavitation in drug-resistant tuberculosis	10
Analysis of multivariate longitudinal immuno-epidemiological data using a pairwise joint modelling approach	10
The upregulation of peripheral CD3-CD56+CD16+ natural killer cells correlates with Th1/Th2 imbalance in asthma patients during acute upper respiratory viral infections	10
Critical role of triglycerides for adiponectin levels in hepatitis C: a joint study of human and HCV core transgenic mice	10
Cycling and activated CD8+ T lymphocytes and their association with disease severity in influenza patients	10
Sec1 regulates intestinal mucosal immunity in a mouse model of inflammatory bowel disease	9
Sex-specific relationship between serum 25-hydroxyvitamin D concentrations and antinuclear antibodies in U.S. adults, NHANES 2001–2004	9
Screening of four lysosome-related genes in sepsis based on RNA sequencing technology	9
Causal relationship between immune cells and telomere length: mendelian randomization analysis	9
Oxidative stress-related circulating miRNA-27a is a potential biomarker for diagnosis and prognosis in patients with sepsis	9
Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice	9
The potential pathogenic roles of S100A8/A9 and S100A12 in patients with MPO-ANCA-positive vasculitis	9
Highly individual- and tissue-specific expression of glycoprotein group A and B blood antigens in the human kidney and liver	9
β-glucan combined with Envafolimab and Endostar as immune rechallenge for metastatic non-small cell lung cancer	9
Similarity measurements of B cell receptor repertoire in baseline mice showed spectrum convergence of IgM	8
TLR7 agonist, DSP-0509, with radiation combination therapy enhances anti-tumor activity and modulates T cell dependent immune activation	8
Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice	8
Evaluation of the relationship between serum interleukin-1β levels and expression of inflammasome-related genes in patients with COVID-19	8
Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis	8
Targeted immune epitope prediction to HHLA2 and MAGEB5 protein variants as therapeutic approach to related viral diseases	8
Monitoring of immunoglobulin treatment compliance of patients with an inborn error of immunity during the pandemic period	8
Soluble programmed death molecule 1 (sPD-1) as a predictor of interstitial lung disease in rheumatoid arthritis	8
Lack of STAT6 enhances murine acute lung injury through NLRP3/p38 MAPK signaling pathway in macrophages	8
Tacrolimus reverses pemphigus vulgaris serum-induced depletion of desmoglein in HaCaT cells via inhibition of heat shock protein 27 phosphorylation	7
Humoral and cellular response to SARS-CoV-2 BNT162b2 mRNA vaccine in hemodialysis patients	7
Type 2 and type 3 innate lymphoid cells at the maternal-fetal interface: implications in preterm birth	7
The effect of serum origin on cytokines induced killer cell expansion and function	7
Regulatory T cells modulate monocyte functions in immunocompetent antiretroviral therapy naive HIV-1 infected people	7
The inhibitory receptor Tim-3 fails to suppress IFN-γ production via the NFAT pathway in NK-cell, unlike that in CD4+ T cells	7
Assessment of autoantibodies in paediatric population with primary immunodeficiencies: a pilot study	6
Immunological characteristics of MAV/06 strain of varicella-zoster virus vaccine in an animal model	6
IWR-1 attenuates the promotional effect of IL-36γ in a mouse model of psoriasis	6
Blood CD3-(CD56 or 16)+ natural killer cell distributions are heterogeneous in healthy adults and suppressed by azathioprine in patients with ANCA-associated vasculitides	6
Anti-inflammatory protein TNFα-stimulated gene-6 (TSG-6) reduces inflammatory response after brain injury in mice	6
Regulatory and effector T cell subsets in tumor-draining lymph nodes of patients with squamous cell carcinoma of head and neck	6
Docosahexaenoic acid supplementation represses the early immune response against murine cytomegalovirus but enhances NK cell effector function	5
Higher cytotoxic activities of CD8+ T cells and natural killer cells from peripheral blood of early diagnosed lung cancer patients	5
Pre-treatment plasma retinol binding protein 4 level and its change after treatments predict systemic treatment response in psoriasis patients	5
Single-cell characterization of the immune heterogeneity of pulmonary hypertension identifies novel targets for immunotherapy	5
Angiopoietin 1 release from human neutrophils is independent from neutrophil extracellular traps (NETs)	5
Brachytherapy for targeting the immune system in cervical cancer patients	5
The augment of regulatory T cells undermines the efficacy of anti-PD-L1 treatment in cervical cancer	5
Characteristics of circulating immune cells in HBV-related acute-on-chronic liver failure following artificial liver treatment	5

A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons	5
Detecting the preoperative peripheral blood systemic immune-inflammation index (SII) as a tool for early diagnosis and prognosis of gallbladder cancer	5
Bcl-3 regulates T cell function through energy metabolism	5
Sepsis induced dysfunction of liver type 1 innate lymphoid cells	5
From bioinformatics to clinical applications: a novel prognostic model of cuproptosis-related genes based on single-cell RNA sequencing data in hepatocellular carcinoma	5
Identification of four mitochondria-related genes in sepsis based on RNA sequencing technology	5
Correction: Thalidomide with blockade of costimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts	5
Chemokine CXCL1 as a potential marker of disease activity in systemic lupus erythematosus	5
Autoimmunity’s enigmatic role: exploring the connection with myalgic encephalomyelitis/chronic fatigue syndrome	5
CD19+CD24hiCD38hi regulatory B cells deficiency revealed severity and poor prognosis in patients with sepsis	4
Interstitial lung diseases (ILD) in common variable immunodeficiency (CVID) patients: a study from Iran	4
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps	4
Systematic evaluation of B-cell clonal family inference approaches	4
Network pharmacology-based strategy to investigate the mechanisms of artemisinin in treating primary Sjögren’s syndrome	4
Transcriptomics explores potential mechanisms for the development of Primary Sjogren’s syndrome to diffuse large B-cell lymphoma in B cells	4
Transcriptomic analysis identifies CYP27A1 as a diagnostic marker for the prognosis and immunity in lung adenocarcinoma	4
Blockade of exosome generation by GW4869 inhibits the education of M2 macrophages in prostate cancer	4
Soluble cytotoxic T-lymphocyte–associated antigen 4 (sCTLA-4) as a potential biomarker for diagnosis and evaluation of the prognosis in Glioma	4
Humoral immune response and safety of Sars-Cov-2 vaccine in people with multiple sclerosis	4
Neutralizing antibody responses assessment after vaccination in people living with HIV using a surrogate neutralization assay	4
Combining machine learning with external validation to explore necroptosis and immune response in moyamoya disease	4
Differential long non-coding RNA expression profile and function analysis in primary Sjogren’s syndrome	4
Immunological factors, important players in the development of asthma	4
Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction	4
Pharmacological activation of rev-erbα suppresses LPS-induced macrophage M1 polarization and prevents pregnancy loss	4
The role of the immune system in early-onset schizophrenia: identifying immune characteristic genes and cells from peripheral blood	4
Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopat	4
miR-486-5p predicted adverse outcomes of SCAP and regulated K. pneumonia infection via FOXO1	3
The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes	3
Transmembrane signaling molecules play a key role in the pathogenesis of IgA nephropathy: a weighted gene co-expression network analysis study	3
Upregulation of PD-1 expression on circulating CD8+ but not CD4+ T cells is associated with tuberculosis infection in health care workers	3
Increased PD-1 expression in livers associated with PD-1-antibody-induced hepatotoxicity	3
Long-term survival after local immunotherapy for malignant gliomas: a retrospective study with 20 years follow-up	3
Reference ranges of T lymphocyte subsets by single-platform among healthy population in southwest China	3
Advanced in immunological monitoring of HIV infection: profile of immune cells and cytokines in people living with HIV-1 in Benin	3
Reduction of peripheral regulatory T cells in active rheumatoid arthritis patients with coronary artery disease	3
High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DRβ1 molecules in Occult hepatitis B infection	3
Assessment of the first presentations of common variable immunodeficiency in a large cohort of patients	3
Oral magnesium reduces levels of pathogenic autoantibodies and skin disease in murine lupus	3
Comparison of the effect of autoclaved and non-autoclaved live soil exposure on the mouse immune system	3
Prevention of M2 polarization and temporal limitation of differentiation in monocytes by extracellular ATP	3
Factors associated with IgG levels in adults with IgG subclass deficiency	3
Nitro-fatty acids decrease type I interferons and monocyte chemoattractant protein 1 in ex vivo models of inflammatory arthritis	3
Effect of conditioned medium from miRNA-34a transfected gastric cancer-associated fibroblast on peripheral blood mononuclear cells	3
Sex differences exist in adult heart group 2 innate lymphoid cells	3
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients	2
CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8+ T cells	2
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension	2
Association of interleukin-17A and chemokine/vascular endothelial growth factor-induced angiogenesis in newly diagnosed patients with bladder cancer	2
Optimized workflow to modify microRNA expression in primary human intravascular cells	2
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor	2
Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats	2
Convergence of endothelial dysfunction, inflammation and glucocorticoid resistance in depression-related cardiovascular diseases	2
Patients with indolent lymphomas are at high risk of infections: experience from a German outpatient clinic	2
RETRACTED ARTICLE: Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of diseas	2
Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sjögren’s syndrome	2
Transcriptomics of type 2 diabetic and healthy human neutrophils	2
TREM2 promotes natural killer cell development in CD3−CD122+NK1.1+ pNK cells	2
Macrophage-targeted anti-CCL2 immunotherapy enhances tumor sensitivity to 5-fluorouracil in a Balb/c-CT26 murine colon carcinoma model measured using diffuse reflectance spectroscopy	2
Immune correlates of cardiovascular co-morbidity in HIV infected participants from South India	2
Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia	2
Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection	2
Dissecting cellular states of infiltrating microenvironment cells in melanoma by integrating single-cell and bulk transcriptome analysis	2
Glycyrrhizin improves the pathogenesis of psoriasis partially through IL-17A and the SIRT1-STAT3 axis	2
The development of a highly sensitive and quantitative SARS-CoV-2 rapid antigen test applying newly developed monoclonal antibodies to an automated chemiluminescent flow-through membrane immunoassay d	2
Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression	2
An efficient method to identify virus-specific TCRs for TCR-T cell immunotherapy against virus-associated malignancies	2
Atypical memory B cells increase in the peripheral blood of patients with breast cancer regardless of lymph node involvement	2
Circular RNA circFADS2 is overexpressed in sepsis and suppresses LPS-induced lung cell apoptosis by inhibiting the maturation of miR-15a-5p	2
The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis	2
Pattern of sensitization to yellow jacket venom and expression of recombinant antigen 5 (Ves v 5) from yellow jacket venom	2
Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy	2
Blood monocyte and dendritic cell profiles among people living with HIV with Mycobacterium tuberculosis co-infection	2
IgG antibody response to SARS-CoV-2 infection and its influencing factors in lymphoma patients	2
Serum IgE in the clinical features and disease outcomes of anti-interferon-γ autoantibodies syndrome	2