OOIR: Observatory of International Research

Papers

(The TQCC of BMC Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
The diagnostic value and validation of IL-22 combined with sCD40L in tuberculosis pleural effusion	67
Integrated bulk RNA sequencing and mass cytometry analysis reveal the circulating immune landscape in ischemic and hemorrhagic Moyamoya disease	55
Increased serum adenosine deaminase activity in patients with adult-onset Still's disease	41
Oxidative stress-related circulating miRNA-27a is a potential biomarker for diagnosis and prognosis in patients with sepsis	39
Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model	35
Incidence of severe adverse events in cancer patients after treatment with immune-checkpoint inhibitors during the COVID- 19 pandemic	26
Clinical applications and diagnostic research of GFAP and NfL in MS and NMOSD: a meta-analysis	20
Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis	20
A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons	18
Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy	17
The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes	15
CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8+ T cells	15
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps	15
Sex differences exist in adult heart group 2 innate lymphoid cells	15
Interstitial lung diseases (ILD) in common variable immunodeficiency (CVID) patients: a study from Iran	14
Systematic evaluation of B-cell clonal family inference approaches	14
Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopat	14
Natural and induced immune responses in oral cavity and saliva	13
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor	13
Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression	12
Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer	12
The digestive system and autoimmunity	12
The decreased of peripheral blood natural killer cell is associated with serum IL-2 level in the renal tubular acidosis in patients with primary sjogren’s syndrome	12
The proportion and phenotypic changes of CD4+CD25−Foxp3+ T cells in patients with untreated rheumatoid arthritis	12
Phenotypic characterization of NK cells in 5-year-old children exposed to maternal HIV and antiretroviral therapy in early-life	11

Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1	11
Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress	11
Evaluation of the effect of the COVID-19 pandemic on depression, anxiety and psychological resilience in patients with primary immunodeficiency	11
Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cells	11
PU.1-CD23 signaling mediates pulmonary innate immunity against Aspergillus fumigatus infection by driving inflammatory response	11
Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy	11
The immune subtypes and landscape of sarcomas	10
Markers of neutrophil activation and some immune and haematological indices in malaria infection during pregnancy	10
Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma	10
Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS	10
Adalimumab and anti-adalimumab LISA-TRACKER immunoassays performance criteria for therapeutic drug monitoring of adalimumab-amgen biosimilar (ABP501)	10
Identification of BTK as an immune-related biomarker for Hashimoto’s thyroiditis by integrated bioinformatic analysis	10
Pathogen exposure influences immune parameters around weaning in pigs reared in commercial farms	10
Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers	10
Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice	9
Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15	9
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication	9
Increased serum IL-2, IL-4, IL-5 and IL-12p70 levels in AChR subtype generalized myasthenia gravis	9
Seroconversion rates following 2 doses of measles- mumps- rubella vaccination given at the ages 12 and 18 months: data for possible additional dose at older age	9
Investigation of KIR/HLA relationship and other clinical variables after T-cell-replete haploidentical bone marrow transplantation in patients with acute myeloid leukemia (AML)	8
Autoimmune cytopenias in inborn errors of immunity: associations with monogenic mutations and immunologic parameters	8
Comprehensive evaluation of the effects of long-term cryopreservation on peripheral blood mononuclear cells using flow cytometry	8
Effect of immune-modulating metronomic capecitabine as an adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma	8
Intervention effect of curcumin on sepsis-associated acute kidney injury via regulation of p300 expression and protein lactylation	8
Pidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes	7
Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction	7
Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection	7
Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice	7
Autoimmunity’s enigmatic role: exploring the connection with myalgic encephalomyelitis/chronic fatigue syndrome	7
Humoral and cellular response to SARS-CoV-2 BNT162b2 mRNA vaccine in hemodialysis patients	7
Identification of four mitochondria-related genes in sepsis based on RNA sequencing technology	7
Neutralizing antibody responses assessment after vaccination in people living with HIV using a surrogate neutralization assay	7
The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis	7
Correction: Thalidomide with blockade of costimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts	7
Bcl-3 regulates T cell function through energy metabolism	7
Nitro-fatty acids decrease type I interferons and monocyte chemoattractant protein 1 in ex vivo models of inflammatory arthritis	7
Optimized workflow to modify microRNA expression in primary human intravascular cells	7
NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis	6
PRMT2 silencing regulates macrophage polarization through activation of STAT1 or inhibition of STAT6	6
RETRACTED ARTICLE: Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of diseas	6
Patients with indolent lymphomas are at high risk of infections: experience from a German outpatient clinic	6
Brucellosis novel multi-epitope vaccine design based on in silico analysis focusing on Brucella abortus	6
Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia	6
Systematic literature reviews to identify epidemiological, clinical, economic and health-related quality of life evidence in activated PI3Kδ syndrome (APDS)	6
Methionine enkephalin(MENK) upregulated memory T cells in anti-influenza response	6
Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sjögren’s syndrome	6
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients	6
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension	6
The predictive value of peripheral blood monocytic myeloid-derived suppressor cells for survival and immunotherapy responses in tumor patients	6
The immune factors have complex causal regulation effects on kidney stone disease: a mendelian randomization study	5

The influences of perfluoroalkyl substances on the rheumatoid arthritis clinic	5
Putative novel outer membrane antigens multi-epitope DNA vaccine candidates identified by Immunoinformatic approaches to control Acinetobacter baumannii	5
The role of immune-inflammatory markers in children with complicated and uncomplicated malaria in Enugu, Nigeria	5
Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases	5
Transcriptomic responses of bat cells to European bat lyssavirus 1 infection under conditions simulating euthermia and hibernation	5
Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity	5
Advances in the Understanding of ocular and nasal lymphatics	5
Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn’s disease correlates with disease activity	5
Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice	5
Bioinformatics designing of an mRNA vaccine for Mokola virus (MOKV) using immunoinformatics as a secure strategy for successful vaccine development	5
Comparative efficacy of preventive vs. therapeutic resveratrol in modulating gut microbiota and alleviating inflammation in DSS-induced colitis	5
Inhibition of CEACAM1 expression in cytokine-activated neutrophils using JAK inhibitors	5
Potential causes and associated conditions with anti-sperm antibody production among infertile males: a systematic literature review	5
Putative new combination vaccine candidates identified by reverse vaccinology and genomic approaches to control enteric pathogens	5
Humoral immune response and changes in peritoneal cell populations in rats immunized against two Leptospira serovars; serovar patoc and serovar pyrogenes	5
The association of peripheral blood inflammatory markers with the distribution patterns of IgE in children with allergen sensitization	5
Interleukin-7 regulates CD127 expression and promotes CD8+ T cell activity in patients with primary cutaneous melanoma	5