OOIR: Observatory of International Research

Papers

(The TQCC of BMC Immunology is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
The diagnostic value and validation of IL-22 combined with sCD40L in tuberculosis pleural effusion	61
Innate lymphoid cell dysfunction during long-term suppressive antiretroviral therapy in an African cohort	51
Integrated bulk RNA sequencing and mass cytometry analysis reveal the circulating immune landscape in ischemic and hemorrhagic Moyamoya disease	34
Immunogenicity of a new enhanced tetanus-reduced dose diphtheria-acellular pertussis (Tdap) vaccine against Bordetella pertussis in a murine model	33
Increased serum adenosine deaminase activity in patients with adult-onset Still's disease	32
Oxidative stress-related circulating miRNA-27a is a potential biomarker for diagnosis and prognosis in patients with sepsis	25
Incidence of severe adverse events in cancer patients after treatment with immune-checkpoint inhibitors during the COVID- 19 pandemic	25
Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis	19
Clinical applications and diagnostic research of GFAP and NfL in MS and NMOSD: a meta-analysis	17
The augment of regulatory T cells undermines the efficacy of anti-PD-L1 treatment in cervical cancer	17
Anti-inflammatory protein TNFα-stimulated gene-6 (TSG-6) reduces inflammatory response after brain injury in mice	17
A survey of the adaptive immune genes of the polka-dot batfish Ogcocephalus cubifrons	17
Histone acetylation risk model predicts prognosis and guides therapy selection in glioblastoma: implications for chemotherapy and anti-CTLA-4 immunotherapy	16
Interstitial lung diseases (ILD) in common variable immunodeficiency (CVID) patients: a study from Iran	15
Natural and induced immune responses in oral cavity and saliva	14
Systematic evaluation of B-cell clonal family inference approaches	14
Platelet-derived extracellular vesicles promote endothelial dysfunction in sepsis by enhancing neutrophil extracellular traps	14
The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes	14
Propofol maintains Th17/Treg cell balance in elderly patients undergoing lung cancer surgery through GABAA receptor	14
Sex differences exist in adult heart group 2 innate lymphoid cells	14
Activation of Toll-like receptor 2 enhances peripheral and tumor-infiltrating CD8+ T cell cytotoxicity in patients with gastric cancer	13
Development and validation of a machine learning-based nomogram for predicting HLA-B27 expression	13
Potential role of IGF-1R in the interaction between orbital fibroblasts and B lymphocytes: an implication for B lymphocyte depletion in the active inflammatory phase of thyroid-associated ophthalmopat	13
CD40 ligand stimulation affects the number and memory phenotypes of human peripheral CD8+ T cells	13
The proportion and phenotypic changes of CD4+CD25−Foxp3+ T cells in patients with untreated rheumatoid arthritis	12

The digestive system and autoimmunity	12
Repression of the expression of proinflammatory genes by mitochondrial transcription factor A is linked to its alternative splicing regulation in human lung epithelial cells	12
The decreased of peripheral blood natural killer cell is associated with serum IL-2 level in the renal tubular acidosis in patients with primary sjogren’s syndrome	12
Phenotypic characterization of NK cells in 5-year-old children exposed to maternal HIV and antiretroviral therapy in early-life	11
Dimethyl itaconate alleviates the pyroptosis of macrophages through oxidative stress	11
Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1	11
Atypical skin conditions of the neck and back as a dermal manifestation of anti-HMGCR antibody-positive myopathy	11
Deep analysis of the major histocompatibility complex genetic associations using covariate analysis and haploblocks unravels new mechanisms for the molecular etiology of Elite Control in AIDS	10
Evaluation of the effect of the COVID-19 pandemic on depression, anxiety and psychological resilience in patients with primary immunodeficiency	10
Pathogen exposure influences immune parameters around weaning in pigs reared in commercial farms	10
Adalimumab and anti-adalimumab LISA-TRACKER immunoassays performance criteria for therapeutic drug monitoring of adalimumab-amgen biosimilar (ABP501)	10
PU.1-CD23 signaling mediates pulmonary innate immunity against Aspergillus fumigatus infection by driving inflammatory response	10
Identification of BTK as an immune-related biomarker for Hashimoto’s thyroiditis by integrated bioinformatic analysis	10
Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma	10
Exhausted phenotype of circulating CD8+ T cell subsets in hepatitis B virus carriers	9
Seroconversion rates following 2 doses of measles- mumps- rubella vaccination given at the ages 12 and 18 months: data for possible additional dose at older age	9
The immune subtypes and landscape of sarcomas	9
Immunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15	9
Increased serum IL-2, IL-4, IL-5 and IL-12p70 levels in AChR subtype generalized myasthenia gravis	9
Markers of neutrophil activation and some immune and haematological indices in malaria infection during pregnancy	9
Oral administration of DNA alginate nanovaccine induced immune-protection against Helicobacter pylori in Balb/C mice	8
Comprehensive evaluation of the effects of long-term cryopreservation on peripheral blood mononuclear cells using flow cytometry	8
Autoimmunity’s enigmatic role: exploring the connection with myalgic encephalomyelitis/chronic fatigue syndrome	8
Investigation of KIR/HLA relationship and other clinical variables after T-cell-replete haploidentical bone marrow transplantation in patients with acute myeloid leukemia (AML)	8
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication	8
Antagonist anti-LIF antibody derived from naive human scFv phage library inhibited tumor growth in mice	8
Effect of immune-modulating metronomic capecitabine as an adjuvant therapy in locoregionally advanced nasopharyngeal carcinoma	8
Correction: Thalidomide with blockade of costimulatory molecules prolongs the survival of alloantigen-primed mice with cardiac allografts	7
Bcl-3 regulates T cell function through energy metabolism	7
Identification of four mitochondria-related genes in sepsis based on RNA sequencing technology	7
Humoral and cellular response to SARS-CoV-2 BNT162b2 mRNA vaccine in hemodialysis patients	7
Pidotimod alleviated experimental autoimmune encephalomyelitis by regulating the balance of splenic lymphocytes	6
Neutralizing antibody responses assessment after vaccination in people living with HIV using a surrogate neutralization assay	6
Patients with indolent lymphomas are at high risk of infections: experience from a German outpatient clinic	6
An efficient method to identify virus-specific TCRs for TCR-T cell immunotherapy against virus-associated malignancies	6
RETRACTED ARTICLE: Tumor microenvironment and immune system preservation in early-stage breast cancer: routes for early recurrence after mastectomy and treatment for lobular and ductal forms of diseas	6
Three important short-chain fatty acids (SCFAs) attenuate the inflammatory response induced by 5-FU and maintain the integrity of intestinal mucosal tight junction	6
The exhaustion of lymphocytes is the main factor that decreases the sensitivity of QFT-GIT detection in silicosis	6
Decreased frequency of Th22 cells and IL-22 cytokine in kidney transplant patients with active cytomegalovirus infection	6
Proinflammatory plasticity towards Th17 paradigm of regulatory T cells consistent with elevated prevalence of TGFBR2 variants in elderly patients with primary immune thrombocytopenia	6
Unsolved mystery of Fas: mononuclear cells may have trouble dying in patients with Sjögren’s syndrome	6
Nitro-fatty acids decrease type I interferons and monocyte chemoattractant protein 1 in ex vivo models of inflammatory arthritis	6
Optimized workflow to modify microRNA expression in primary human intravascular cells	6
Methionine enkephalin(MENK) upregulated memory T cells in anti-influenza response	6
Expression of the immune checkpoint molecules CD226 and TIGIT in preeclampsia patients	6
PRMT2 silencing regulates macrophage polarization through activation of STAT1 or inhibition of STAT6	6
Neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and other hematological parameters in psoriasis patients	5
NLRP3 inflammasome up-regulates major histocompatibility complex class I expression and promotes inflammatory infiltration in polymyositis	5
Inhibition of CEACAM1 expression in cytokine-activated neutrophils using JAK inhibitors	5
Transcriptomic responses of bat cells to European bat lyssavirus 1 infection under conditions simulating euthermia and hibernation	5

Advances in the Understanding of ocular and nasal lymphatics	5
mTORC2 is crucial for regulating the recombinant Mycobacterium tuberculosis CFP-10 protein-induced phagocytosis in macrophages	5
The predictive value of peripheral blood monocytic myeloid-derived suppressor cells for survival and immunotherapy responses in tumor patients	5
The immune factors have complex causal regulation effects on kidney stone disease: a mendelian randomization study	5
Putative novel outer membrane antigens multi-epitope DNA vaccine candidates identified by Immunoinformatic approaches to control Acinetobacter baumannii	5
Serum IL-5, POSTN and IL-33 levels in chronic rhinosinusitis with nasal polyposis correlate with clinical severity	5
Bioinformatics designing of an mRNA vaccine for Mokola virus (MOKV) using immunoinformatics as a secure strategy for successful vaccine development	5
Putative new combination vaccine candidates identified by reverse vaccinology and genomic approaches to control enteric pathogens	5
Brucellosis novel multi-epitope vaccine design based on in silico analysis focusing on Brucella abortus	5
Association of the systemic immune-inflammation index with clinical outcomes in acute myocardial infarction patients with hypertension	5
Hyperactivation and enhanced cytotoxicity of reduced CD8+ gamma delta T cells in the intestine of patients with Crohn’s disease correlates with disease activity	5
The influences of perfluoroalkyl substances on the rheumatoid arthritis clinic	5
Influenza virus-like particle vaccine containing both apical membrane antigen 1 and microneme-associated antigen proteins of Plasmodium berghei confers protection in mice	5