Expert Opinion on Biological Therapy

Article	Citations
Assessment of real-life patient handling experience of AVT02 administered subcutaneously via autoinjector in patients with moderate to severe active rheumatoid arthritis: an open-label, single-arm cli	113
Pharmacokinetics and pharmacodynamics of the proposed biosimilar denosumab GP2411 and reference denosumab in healthy males	58
Microbiota transplantation and administration of live biotherapeutic products for the treatment of dysbiosis-associated diseases	53
Aflibercept biosimilars – so near, yet so far	52
Biosimilars and access to biologic therapy in immune-mediated diseases	44
Management of chronic recurrent multifocal osteomyelitis: review and update on the treatment protocol	44
Antibody drug conjugates for glioblastoma: current progress towards clinical use	40
A comprehensive overview on the anti-inflammatory, antitumor, and ferroptosis functions of bromelain: an emerging cysteine protease	39
Efficacious dosing regimens for anti-TNF therapies in inflammatory bowel disease: where do we stand?	38
The endosomal-lysosomal system in ADC design and cancer therapy	34
A review of bridging clinical studies between different presentations of biological products approved by the United States Food and Drug Administration (US FDA)	33
Development and Clinical Translation Considerations for the Next Wave of Gene Modified Hematopoietic Stem and Progenitor Cells Therapies	31
Correction	31
What’s new in the use of antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) DNA cross-linkers for cancer therapy?	27
Optimization of radiation target volume for locally advanced esophageal cancer in the immunotherapy era	26
Biologics in severe asthma: Outcomes in clinical trials-Similarities and differences	25
Signaling new therapeutic opportunities: cytokines in prostate cancer	24
Tildrakizumab: the value of a personalized and flexible approach for treating moderate-to-severe plaque psoriasis in patients with high body weight or high disease burden	24
Idecabtagene vicleucel (ide-cel) for the treatment of triple-class exposed relapsed and refractory multiple myeloma	21
Tebentafusp in advanced uveal melanoma: proof of principle for the efficacy of T-cell receptor therapeutics and bispecifics in solid tumors	21
Improving patient access to biosimilar tumor necrosis factor inhibitors in immune-mediated inflammatory disease: lessons learned from Norway	21
Development of multi-epitope vaccine constructs for non-small cell lung cancer (NSCLC) against USA human leukocyte antigen background: an immunoinformatic approach toward future vaccine designing	20
Long-acting delivery and therapies for neovascular age-related macular degeneration	20
Real-world observational cohort study of treatment patterns and safety outcomes of infliximab biosimilar CT-P13 for the treatment of inflammatory bowel disease (CONNECT-IBD)	18
Correction	18

Is there still a role for talimogene laherparepvec (T-VEC) in advanced melanoma? An indirect efficacy comparison of T-VEC plus ipilimumab combination therapy versus T-VEC alone as salvage therapy in u	17
What’s new and what’s next for biological and targeted synthetic treatments in psoriatic arthritis?	17
Moving toward personalized approaches in the management of lupus nephritis	17
A randomized pharmacokinetic/pharmacodynamic study comparing the bioequivalence of potential biosimilar candidate P044 with reference medicine in healthy volunteers	17
Safety of COVID-19 vaccines in patients with psoriasis undergoing therapy with anti-interleukin agents	17
Unmet needs in cervical cancer – can biological therapies plug the gap?	16
Need for a risk-based control strategy for managing glycosylation profile for biosimilar products	16
Reduced doses of biological therapies in psoriasis: a new potentially “sustainable” frontier of psoriasis treatment	16
Treating episodic migraine with precision: the evolving landscape of targeted therapies driven by insights in disease biology	16
Strategies for extending the half-life of biotherapeutics: successes and complications	15
Sibeprenlimab, which neutralizes A PRoliferation Inducing Ligand (APRIL), as a new approach to treating IgA nephropathy	15
Efficacy and safety of biosimilar trastuzumab (CT-P6) in routine clinical practice in the Republic of Korea: a real-world post-marketing surveillance study	15
Predicting and overcoming poor patient responses to sublingual immunotherapy for allergic diseases	15
The nail in psoriatic arthritis: new insights into prognosis and treatment	14
Biosimilars in chronic inflammatory diseases: facts and remaining questions 5 years after their introduction in Europe	14
An evaluation of odronextamab for the treatment of multiple subtypes of relapsed/refractory B-cell non-Hodgkin lymphoma	14
Immunotherapy in cutaneous melanoma and biologics in psoriatic disease: similarities and differences from a clinical multidisciplinary perspective	14
Overcoming efficiency limitations of CAR-T cell therapy in antigen-heterogeneous solid tumors	14
Dynamics of biological markets with multiple biosimilar competitors in the United States	14
Management of proctitis in ulcerative colitis and the place of biological therapies	14
Progress towards the clinical use of antimicrobial peptides: challenges and opportunities	14
Locked and loaded: engineering and arming oncolytic adenoviruses to enhance anti-tumor immune responses	14
Looking ahead to CD3, T-cell engager bispecific antibodies for hematological malignancies	14
With guselkumab, does the dual mechanisms to inhibit IL-23, help in ulcerative colitis?	13
Emerging peptide-based technology for biofilm control	13
Review of emerging biological therapies for recurrent and advanced metastatic cervical cancer	13
Current and emerging monoclonal antibodies for treating familial hypercholesterolemia in children	13
Biological agents targeting interleukin-13 for atopic dermatitis	13
A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease	13
Biologic therapy for chronic spontaneous urticaria in pediatrics and adolescents: current landscape, challenges, and future perspectives	13
The management of axial spondyloarthritis with cutting-edge therapies: advancements and innovations	13
Where do we stand with radioimmunotherapy for acute myeloid leukemia?	13
The status and preparation for the next decade of biosimilars in the Middle Eastern and North African region	12
Do we need bamlanivimab? Is etesevimab a key to treating Covid-19?	12
Optimizing withdrawal strategies for anti-TNF-α therapies in rheumatoid arthritis	12
Recent advances in delivering RNA-based therapeutics to mitochondria	12
Considerations for the development of monoclonal antibodies to address new viral variants in COVID-19	12
Comparative efficacy, safety and immunogenicity of biosimilars and their reference biologic drugs in ankylosing spondylitis: a systematic review and meta-analysis of randomized controlled trials	12
State of the art of the molecular hyperselection to guide treatment with anti-EGFR antibodies in RAS WT mCRC: implications for clinical practice and future perspectives	11
Trajectories of biologic drug use before, during and after pregnancy: an Italian cohort study from the VALORE project	11
Efficacy of trastuzumab in HER-2-positive advanced extramammary Paget’s disease	11
An evaluation of pozelimab for the treatment of CHAPLE disease	11
Personalizing immunotherapy for renal cell carcinoma: how far have we come?	11
Current status of developing tissue engineering vascular technologies	11
Microbiome therapeutics for the treatment of recurrent Clostridioides difficile infection	11
Pembrolizumab: first anti-PD-1/L1-based regimen for first-line treatment of advanced esophageal cancer in Japan	11
Assessment of cell-binding capacity of shed rAAV particles after gene therapy vector administration: implications for environmental risk and hygiene recommendations	11
Clinical utility of checkpoint inhibitors against metastatic bladder cancer: overcoming challenges to find a way forward	11
Cilta-cel, a BCMA-targeting CAR-T therapy for patients with multiple myeloma	11
Psoriatic arthritis improved on risankizumab: does the presence of psoriatic arthritis mean a drug approved for psoriatic arthritis has to be prescribed?	11

Biosimilars and interchangeable biosimilars: facts every prescriber, payor, and patient should know. Insulins perspective	11
Head and neck atopic dermatitis: still a challenging manifestation in the biologic era	10
Biosimilars in osteoporosis treatment: focus on denosumab	10
The immunologic role of IL-23 in psoriatic arthritis: a potential therapeutic target	10
Belimumab patient profile in Spain: evolution during the last decade and future directions	10
Predisposition to conjunctivitis and male sex reduces drug survival of dupilumab in adults and adolescents	10
Etranacogene dezaparvovec-drlb gene therapy for patients with hemophilia B (congenital factor IX deficiency)	10
Antibody therapeutics for epithelial ovarian cancer	10
Pooled safety analysis from the VOLTAIRE clinical trials of adalimumab-adbm and adalimumab reference product in patients with rheumatoid arthritis, Crohn’s disease, and chronic plaque psoriasis	10
Non-traditional approaches for control of antibiotic resistance	10
Fecal microbiota transplantation: a review on current formulations inClostridioides difficileinfection and future outlooks	10
An evaluation of risankizumab for the treatment of moderate-to-severe ulcerative colitis	10
Targeting virus-specific CD8+ T cells for treatment of chronic viral hepatitis: from bench to bedside	10
Clinical management and innovation in fracture non-union	10
Real-world efficacy and safety of vedolizumab in managing ulcerative colitis versus Crohn’s disease: results from an Italian multicenter study	10
Treating psoriasis in the elderly: biologics and small molecules	10
Correction	9
Prospects of cell chemotactic factors in bone and cartilage tissue engineering	9
Harmonizing PD-L1 testing in metastatic triple negative breast cancer	9
An evaluation of nadofaragene firadenovec-vncg for the treatment of high-risk BCG-unresponsive non-muscle-invasive bladder cancer	9
X-linked myotubular myopathy: an untreated treatable disease	9
Comparison of the efficacy and safety of rapid-acting insulin analogs, lispro versus aspart, in the treatment of diabetes: a systematic review of randomized controlled trials	9
Tumor-infiltrating lymphocyte therapy for lung cancer and its future paradigms	9
Prostate cancer immunotherapy	9
Monoclonal antibodies for dyslipidemia in adults: a focus on vulnerable patients groups	9
An overview of site-specific methods for achieving antibody drug conjugates with homogenous drug to antibody ratio	9
An evaluation of mepolizumab as an add-on maintenance treatment for severe eosinophilic asthma	9
Epcoritamab in B-cell malignancies: current status and prospects	9
Pharmacokinetics and safety of candidate tocilizumab biosimilar CT-P47 administered by auto-injector or pre-filled syringe: a randomized, open‑label, single-dose phase I study	9
Sargramostim in acute radiation syndrome	9
Hemophilia A gene therapy: current and next-generation approaches	8
Ravulizumab for the treatment of myasthenia gravis	8
Perspectives on the use of biological therapies for the treatment of asthma in low-middle income countries	8
Distinguishing features of a novel humanized anti-EGFR monoclonal antibody based on cetuximab with superior antitumor efficacy	8
Belantamab mafodotin in multiple myeloma	8
Current treatment goals are achieved by the majority of patients with atopic dermatitis treated with tralokinumab: results from a multicentric, multinational, retrospective, cohort study	8
Biologics in rectal cancer	8
Stem cell therapy for acute myocardial infarction: Mesenchymal Stem Cells and induced Pluripotent Stem Cells	8
Prospects for CAR T cell immunotherapy in autoimmune diseases: clues from Lupus	8
CAR T cells for solid tumors – developments to watch in 2023	8
Rilonacept for the treatment of recurrent pericarditis	8
An up-to-date review of approved and emerging antibody therapies for idiopathic pulmonary fibrosis	8
Do we need alternative PD-1 inhibitors for the treatment of renal cell carcinoma?	8
Ex vivo gene therapy for lysosomal storage disorders: future perspectives	8
Systematic review: effectiveness and safety of switching between originator infliximab and biosimilar infliximab in patients with inflammatory bowel disease	8
Second-line strategies after anti-TNF failure in chronically active, moderate-to-severe ulcerative colitis: a retrospective, multicentre cohort study	7
Long-term progression-free survival in non-small cell lung cancer patients: a spotlight on bevacizumab and its biosimilars	7
Perspectives on the de-escalation of anti-CD20 monoclonal antibodies in patients with multiple sclerosis	7
The future of cancer vaccines against colorectal cancer	7
Monoclonal antibodies against pediatric ulcerative colitis: a review of clinical progress	7
The future of interleukin gene therapy in head and neck cancers	7
An evaluation of secukinumab for the treatment of moderate-to-severe hidradenitis suppurativa	7
Monoclonal antibodies for the management of central nervous system diseases: clinical success and future strategies	7
“Full-naïve” patients: the impact of previous methotrexate, cyclosporine, and acitretin on first-line biologics response in the treatment of moderate-to-severe psoriasis – a monocentric retrospective	7
An evaluation of ravulizumab for the treatment of neuromyelitis optica spectrum disorder	7
The future of aptamers in cancer diagnosis, prognosis and treatment	7
Will zilebesiran, an RNA interference therapy, be effective, safe, and improve the treatment of hypertension?	7
Bispecific antibodies targeting CD20xCD3 in immunotherapy for adult B-cell lymphoma: insights from the 65th American Society of Hematology 2023 annual meeting	7
The future of cellular therapy for the treatment of renal cell carcinoma	7
Pharmacokinetics, pharmacodynamics, safety and immunogenicity of recombinant, fully human anti-RANKL monoclonal antibody (MW031) versus denosumab in Chinese healthy subjects: a single-center, randomiz	7
Effectiveness of biological therapy in reducing psoriasis-related cardiovascular risk	7
An evaluation of rozanolixizumab-noli for the treatment of anti-AChR and anti-MuSK antibody-positive generalized myasthenia gravis	7
Pembrolizumab for metastatic castration-resistant prostate cancer: trials and tribulations	7
Treatment options for advanced hepatocellular carcinoma: the potential of biologics	7
Non-TNF biologics and their biosimilars in rheumatoid arthritis	7
Rotavirus vaccines: progress and new developments	7
Perceptions of patients with inflammatory bowel diseases on switching from reference product adalimumab to biosimilar adalimumab-atto	7
The role of immune checkpoint inhibitors for patients with advanced stage microsatellite stable colorectal cancer and high tumor mutation burden: quantity or quality?	6
Comparison of the outcomes between early and late anti-tumor necrosis factor therapy in patients with enthesitis-related subcategory of juvenile idiopathic arthritis: a multi-center study in Southeast	6
Biological therapies in patients with liver disease: are they really lifesavers?	6
Gene therapy for choroideremia: progress, potential and pitfalls	6
The ULTIMATE trials: are there advantages of ublituximab over teriflunomide in relapsing multiple sclerosis?	6
Perceptions of airway gene therapy for cystic fibrosis	6
Pharmacokinetic and pharmacodynamic similarity of biosimilar natalizumab (PB006) to its reference medicine: a randomized controlled trial	6
The history of Crohn’s perianal fistula treatment with mesenchymal stem cells: the story of darvadstrocel	6
Applications of mesenchymal stem cells in ocular surface diseases: sources and routes of delivery	6
Advanced therapies targeting IL-23: clinical outcomes in ulcerative colitis	6
Immune checkpoint inhibitors for the treatment of melanoma	6
Progress in second-line antibody therapies for advanced esophageal squamous cell carcinoma	6
An evaluation of glofitamab, the first fixed-duration bispecific antibody for relapsed or refractory large B-cell lymphomas	6

Could siRNA therapeutics change the way we treat dyslipidemia?	6
Hypoxic storage of red blood cells to improve transfusion outcomes in hematological malignancies	6
Safety of dupilumab in T2 airways conditions: focus on eosinophilia across trials and real-life evidence	6
Bispecific antibodies in immunotherapy for adult acute leukemia: latest updates from the 65th American Society of Hematology 2023 Annual Meeting	6
Efficacy and safety of intravitreal anti-VEGF therapy in diabetic retinopathy: what we have learned and what should we learn further?	6
Current and preclinical treatment options for Merkel cell carcinoma	6
Literature review and expert opinion on diagnosis and current management of generalized pustular psoriasis	6
Correction	6
Self-reported efficacy and safety of infliximab and adalimumab biosimilars after non-medical switch in patients with inflammatory bowel disease: results of a multicenter survey	6
The potential of antibody-drug conjugates for effective therapy in diffuse large B-cell lymphoma	5
An evaluation of datopotamab deruxtecan for the treatment of non-small cell lung cancer	5
Elotuzumab in multiple myeloma	5
Infliximab biosimilar GP1111: a review of 5 years’ post-approval experience	5
Oncolytic virus therapy for malignant gliomas: entering the new era	5
Combination of HER2-targeted agents with immune checkpoint inhibitors in the treatment of HER2-positive breast cancer	5
Checkpoint inhibition for early-stage hormone receptor-positive breast cancer	5
Recent developments in CD19-targeted therapies for follicular lymphoma	5
Bintrafusp alfa and its unsuccessful development journey towards cervical cancer treatment	5
Nivolumab + relatlimab for the treatment of unresectable or metastatic melanoma	5
Reduction/elimination of blood eosinophils in severe asthma: should there be a safety consideration?	5
Therapeutic monoclonal antibodies for COVID-19 management: an update	5
Use of rilonacept in patients with recurrent pericarditis during COVID-19 disease	5
Real-life data of etanercept efficacy and safety in juvenile idiopathic arthritis: a 24-month retrospective study at a single center	5
Is sotatercept, which traps activins and growth differentiation factors, a new dawn in treating pulmonary arterial hypertension (PAH)?	5
Navigating the landscape of immune checkpoint inhibitors and novel immunotherapies in melanoma: long-term outcomes, progress, and challenges	5
Genetic screening in new onset inflammatory bowel disease during anti-interleukin 17 therapy: unmet needs and call for action	5
Meta-analysis of response rates to first-line salvage treatment after CAR-T therapy failure in large B-cell lymphoma patients	5
Toward the integration of biosimilars into pediatric rheumatology: adalimumab ABP 501 experience of PeRA research group	5
Does pharmacological intervention prevent or delay the onset of psoriatic arthritis among psoriasis patients?	5
Biological therapies for hemophagocytic lymphohistiocytosis: current knowledge and future perspectives	5
Cost per responder of Adalimumab biosimilars MSB11022 and ABP 501 versus the originator and methotrexate in chronic plaque psoriasis	5
Biologics for dengue prevention: up-to-date	5
Place in therapy of anti-IL-17 and 23 in psoriasis according to the severity of comorbidities: a focus on cardiovascular disease and metabolic syndrome	5
Pathogenesis-oriented therapy of psoriasis using biologics	5
The evolving therapeutic landscape of diabetic retinopathy	5
Experts’ review: the emerging roles of romiplostim in immune thrombocytopenia (ITP)	5
Sarilumab in the treatment of rheumatoid arthritis: future perspectives	4
Effect of biological DMARDs and JAK inhibitors in pain of chronic inflammatory arthritis	4
Emerging role of monoclonal antibodies in the treatment of IgA nephropathy	4
Preventing organ damage in systemic lupus erythematosus: the impact of early biological treatment	4
Targeting cervical cancer with anti-PD-1 antibodies: what is new?	4
Evaluation of canine bone marrow-derived mesenchymal stem cells for experimental full-thickness cutaneous wounds in a diabetic rat model	4
Medical students’ knowledge and awareness levels about biologics and biosimilars: the earlier the better?	4
Short and long-term economic implications of biosimilars	4
ANDROMEDA: Dara-VCd for newly diagnosed AL amyloidosis: the next galaxy or a new standard of care?	4
Targeting IL-17A for the treatment of pustular psoriasis: a comprehensive review	4
KRAS mutations in metastatic colorectal cancer: from a de facto ban on anti-EGFR treatment in the past to a potential biomarker for precision medicine	4
Addressing practical challenges with bispecific antibody therapy in multiple myeloma	4
Pharmacokinetic similarity study comparing the biosimilar candidate, LY05008, with its reference product dulaglutide in healthy Chinese male subjects	4
Safety and effectiveness of efgartigimod for intravenous infusion in patients with generalized myasthenia gravis: an interim analysis of Japanese post-marketing surveillance	4
Optimizing the use of vilobelimab for the treatment of COVID-19	4
Current evidence on the use of the adalimumab biosimilar SB5 (Imraldi TM ): a multidisciplinary perspective	4
The cell replacement therapeutic potential of human pluripotent stem cells	4
Chasing optimal first-in-human (FIH) starting dose for biotherapeutics in oncology	4
Clinical advances in biological therapy for generalized pustular psoriasis: a review	4
Challenges and opportunities when transitioning from in vivo gene replacement to in vivo CRISPR/Cas9 therapies – a spotlight on hemophilia	4
Conditionally active T cell engagers for the treatment of solid tumors: rationale and clinical development	4
T-cell redirecting bispecific antibody treatment in multiple myeloma: current knowledge and future strategies for sustained T-cell engagement	4
Should CAR-T cell therapy be considered a standard of care for patients with refractory diffuse large B-cell lymphoma in second line treatment?	4
Taming the beast: engineering strategies and biomedical potential of antibody-based cytokine mimetics	4
Randomized, double-blind, multicenter study to evaluate efficacy, safety, tolerability, and immunogenicity between AVT04 and the reference product ustekinumab in patients with moderate-to-severe chron	4
Perispinal etanercept stroke trial design: PESTO and beyond	4
Adverse event reporting of marketed biosimilar and biological monoclonal antibody cancer treatments in the United States	4
Monoclonal antibodies as adjuvant therapies for resected melanoma	4
Correction	4
Transitioning immunotherapy in neuromyelitis optica spectrum disorder – when and how to switch	4
A Systematic Review on Infliximab Biosimilar SB2: From Pre-Clinical Data to Real-World Evidence	4
Immunobiology of biliary tract cancer and recent clinical findings in approved and upcoming immune checkpoint inhibitors	4
Emerging anti-spike monoclonal antibodies against SARS-CoV-2	4
Biosimilars in pediatric rheumatology: innovations, challenges, and opportunities	3
Corticosteroids, hyaluronic acid, platelet-rich plasma, and cell-based therapies for knee osteoarthritis - literature trends are shifting in the injectable treatments’ evidence: a systematic review an	3
Recent advances in stem cell therapy for erectile dysfunction: a narrative review	3
Clinical use of biologics in juvenile idiopathic arthritis: lessons learned from real-world studies	3
Pembrolizumab with chemotherapy, with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer	3
Biologics for psoriasis: is there any unmet need left?	3
Biological therapy in elderly patients with acute myeloid leukemia	3
The economics of biosimilars and challenges to biosimilar adoption in low- and middle-income countries	3
What is ‘ chronic ’ pustular psoriasis? Identifying candidates for long-term subcutaneous spesolimab treatment	3
Regulatory and clinical development to support the approval of advanced therapies medicinal products in Japan	3
Mosunetuzumab for the treatment of follicular lymphoma	3
What role can LAG-3-blocking antibodies play in melanoma therapy?	3
Successes and failures: the latest advances in the clinical development of amyloid–β–targeting monoclonal antibodies for treating Alzheimer's disease	3
Antibody-drug conjugates in oncology: insights into Current challenges	3
Injectable and adhesive hydrogels for dealing with wounds	3
A plain language summary of the pooled safety results of adalimumab-adbm from the VOLTAIRE clinical trials in people with rheumatoid arthritis, Crohn’s disease, and chronic plaque psoriasis	3
Recent developments and industry interest in gene therapy for Duchenne muscular dystrophy	3
Biological therapies for myasthenia gravis	3
A randomized, double-masked parallel-group, multicenter clinical study evaluating the efficacy and safety of the biosimilar candidate AVT06 compared to the reference product aflibercept in participant	3
Next steps for the optimization of exon therapy for Duchenne muscular dystrophy	3
Switching CGRP(r) MoAbs in migraine: what evidence?	3
Management of metastatic melanoma with combinations including PD-1 inhibitors	3
Antibody-based therapeutics for chronic rhinosinusitis with nasal polyps	3
Adjuvant immunotherapy for locally advanced renal cell carcinoma	3
Developing combination therapies with biologics in triple-negative breast cancer	3
Current status of mucosal vaccines against SARS-CoV2: a hope for protective immunity	3