Current Opinion in Pharmacology

Article	Citations
Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology	88
Editorial Board	79
Editorial overview: Immune regulation and cancers	73
Established and novel human translational models to advance cystic fibrosis research, drug discovery, and optimize CFTR-targeting therapeutics	57
Editorial Board	57
Routine neoadjuvant chemotherapy for all patients with resectable pancreatic ductal adenocarcinoma? A review of the evidence	55
Editorial overview – 2022 respiratory issue: Cystic fibrosis pathophysiology, models, and novel therapies	43
Editorial Board	42
Editorial Board	41
Lipid raft disruption as an opportunity for peripheral analgesia	41
Editorial Board	36
Non-alcoholic fatty liver disease: Current therapeutic options	33
MicroRNA: A mediator of diet-induced cardiovascular protection	32
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling	32
Tropical fruits from Australia as potential treatments for metabolic syndrome	31
Dietary serine supplementation: Friend or foe?	31
Splice-switching as cancer therapy	30
Elexacaftor–tezacaftor–ivacaftor: The new paradigm to treat people with cystic fibrosis with at least one p.Phe508del mutation	30
Stress, kisspeptin, and functional hypothalamic amenorrhea	29
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer	29
Pharmacologic treatment of gastroparesis: What is (still) on the horizon?	29
New CARs on and off the road: challenges and new developments in CAR-T cell therapy	28
Quantitative assessment of volumetric muscle loss: Dual-energy X-ray absorptiometry and ultrasonography	28
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development	28
Host membrane proteins in the HIV-induced membrane fusion: Role in pathogenesis and therapeutic potential of autoantibodies	27

Current pharmacological treatment of hepatocellular carcinoma	27
Nutraceuticals use and type 2 diabetes mellitus	25
Metabolic regulation of tissue-resident memory CD8+ T cells	25
Interrogating the function of GABAA receptors in the brain with optogenetic pharmacology	25
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?	24
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration	24
Nutraceuticals in mental diseases — Bridging the gap between traditional use and modern pharmacology	23
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies	22
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”	21
Targeting the soluble epoxide hydrolase pathway as a novel therapeutic approach for the treatment of pain	21
Drug effects on neuropeptides and their receptors: Big hopes but moderate success in the treatment of chronic pain	21
Recent advances in emerging PCOS therapies	21
Balancing Genome Integrity and Carcinogenesis: Insights into DNA Damage Response, Repair Pathways, and Cancer Therapies	21
Emerging drugs for the treatment of primary sclerosing cholangitis	21
Circulating factors that influence the central nervous system remyelination	21
Photopharmacological control of cell signaling with photoswitchable lipids	20
The active kinome: The modern view of how active protein kinase networks fit in biological research	20
Corrigendum to ‘JAK inhibitors: Current position in treatment strategies for use in inflammatory bowel disease’	20
Beyond the AMPA receptor: Diverse roles of SynDIG/PRRT brain-specific transmembrane proteins at excitatory synapses	19
Integrating network pharmacology: The next-generation approach in ocular drug discovery	19
Photoswitchable allosteric modulators for metabotropic glutamate receptors	19
The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: A mini-review of the potential mechanisms	19
The 2013–2016 Ebola virus disease outbreak in West Africa	19
Disease-modifying therapies in short bowel syndrome	18
Novel strategies to promote resolution of inflammation to treat lower extremity artery disease	18
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe	18
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers	18
New developments in treatments for systemic vasculitis	18
The role of extracellular ATP in homeostatic immune cell migration	18
Impact of amino acids on microglial activation and CNS remyelination	18
Editorial Board	17
Editorial Board	17
The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids	17
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder	17
Current status of hepatitis delta	17
Editorial overview: Endocrine and metabolic diseases (2023)	16
Editorial Board	16
Cancer 2021: New therapeutic approaches for the treatment of cancer — building on advances in cancer biology and the molecular genetics of cancer	16
Gastrointestinal issue: Advances in gastrointestinal oncology	16
Editorial overview: Neuroscience: Advances in the field	15
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction	15
Editorial Board	15
Artemisinins and their impact on inhibitory neurotransmission	15
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?	15
Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?	15
Optofluidic neural interfaces for in vivo photopharmacology	15
The complement pathway as a therapeutic target for neovascular age-related macular degeneration-mediated subretinal fibrosis	14
Corticosteroids and circadian rhythms in the cardiovascular system	14
Photo-isomerizable tweezers to probe ionotropic receptor mechanisms	14
Practical application of breath tests in disorders of gut–brain interaction	14

Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss	14
From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches	14
Optic nerve regeneration: Potential treatment approaches	14
Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases	14
Nonsteroidal mineralcorticoid receptor antagonists: Novel therapeutic implication in the management of patients with type 2 diabetes	14
How organoids can improve personalized treatment in patients with gastro-esophageal tumors	13
A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease	13
RAD51 paralogs: Expanding roles in replication stress responses and repair	13
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	13
Targeting the altered duodenal microenvironment in functional dyspepsia	13
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation	13
Purinergic signalling in graft-versus-host disease	13
Therapeutic strategies for treating juvenile idiopathic arthritis	13
Corrigendum to “Metformin: Still the sweet spot for CV protection in diabetes?” [Curr Opin Pharmacol 54 (2020) 202–208]	13
Light-activated receptor tyrosine kinases: Designs and applications	13
Photopharmacology for vision restoration	13
Remyelinating strategies: What can be learned from normal brain development	13
Adoptive cell therapy for solid tumors: Chimeric antigen receptor T cells and beyond	13
Analgesic potential of voltage gated sodium channel modulators for the management of pain	13
Type 2 diabetic women are not small type 2 diabetic men: Sex-and-gender differences in antidiabetic drugs	12
The potential role of oxytocin in addiction: What is the target process?	12
Applications of chemogenetics in non-human primates	12
Recent developments and strategies of Ebola virus vaccines	12
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity	12
Chronotherapy of cardiac and vascular disease: timing medications to circadian rhythms to optimize treatment effects and outcomes	12
Role of HSV-1 in Alzheimer's disease pathogenesis: A challenge for novel preventive/therapeutic strategies	12
Adenosine signaling as target in cardiovascular pharmacology	12
The potential pharmacological mechanisms of β-hydroxybutyrate for improving cognitive functions	12
Polyphenols affect the humoral response in cancer, infectious and allergic diseases and autoimmunity by modulating the activity of TH1 and TH2 cells	12
Hormonal drugs for the treatment of endometriosis	12
Targeting fibroblast-like synoviocytes in rheumatoid arthritis	12
Hepatic arterial infusion chemotherapy for patients with hepatocellular carcinoma: Applicability in Western countries	12
Pancreatic alpha cells and glucagon secretion: Novel functions and targets in glucose homeostasis	12
Gestational diabetes: Implications for fetal growth, intervention timing, and treatment options	11
Editorial overview: Special issue on “Rheumatology: Therapeutic advances for autoimmune and musculoskeletal diseases”	11
Treatments targeting the luminal gut microbiota in patients with irritable bowel syndrome	11
Preclinical pharmacology modeling of chimeric antigen receptor T therapies	11
Genetic risk scores and personalization of care in fatty liver disease	11
Pharmacologic approaches to prevent skeletal muscle atrophy after spinal cord injury	11
Advances in lupus therapeutics: Achieving sustained control of the type I interferon pathway	11
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway	11
Towards eradication of HBV: Treatment approaches and status of clinical trials	11
Drug repurposing in skeletal muscle ion channelopathies	11
Biased signalling in analgesic research and development	11
Therapeutic innovations for geographic atrophy: A promising horizon	10
Nicotinamide mononucleotide: An emerging nutraceutical against cardiac aging?	10
Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration	10
Update on anti-fibrotic pharmacotherapies in skeletal muscle disease	10
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis	10
Editorial overview: Introduction to the musculoskeletal section of current opinion in pharmacology	10
Dementia therapeutics and cognitive rehabilitation	10
The expanding role of split protein complementation in opsin-free optogenetics	10
Three-dimensional culture models to study glioblastoma — current trends and future perspectives	10
Cardiac circadian rhythms in time and space: The future is in 4D	10
Targeting KNDy neurons to control GnRH pulses	10
Pharmacology of pannexin channels	10
Novel treatments in multidrug-resistant tuberculosis	9
NMR applications to GPCR recognition by peptide ligands	9
Modulating regulatory T cell migration in the treatment of autoimmunity and autoinflammation	9
Management of blood pressure disorders in individuals with spinal cord injury	9
KRAS inhibition in metastatic colorectal cancer: An update	9
Purinergic signaling pathway in severe COVID-19	9
Targeting cAMP signaling compartments in iPSC-derived models of cardiovascular disease	9
AI-driven GPCR analysis, engineering, and targeting	9
Priming metabolism with the type 5 phosphodiesterase: the role of cGMP-hydrolyzing enzymes	9
Fluorescent chemigenetic actuators and indicators for use in living animals	9
Targeting the endocannabinoid system for the management of low back pain	9
Role of O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins in diabetic cardiovascular complications	9
Editorial Board	8
Eosinophilic esophagitis: New molecules, better life?	8
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?	8
Reviewing the toolbox for degrader development in oncology	8
Role of specific CDKs in regulating DNA damage repair responses and replication stress	8
A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury	8
The use of hormone stimulation in male infertility	8
Publisher’s Note	8
Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance	8
The role of Pannexin-1 channels, ATP, and purinergic receptors in the pathogenesis of HIV and SARS-CoV-2	8
The role of extracellular ATP and P2X receptors in the pathogenesis of HIV-1	8
Optical control of Class A G protein-coupled receptors with photoswitchable ligands	8

Neuroinflammation in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection: Pathogenesis and clinical manifestations	8
Low FODMAP diet beyond IBS: Evidence for use in other conditions	8
Editorial Board	8
Editorial Board	8
Precision medicine in idiopathic pulmonary fibrosis therapy: From translational research to patient-centered care	8
Immune dysfunction after spinal cord injury – A review of autonomic and neuroendocrine mechanisms	8
Treatment of early rheumatoid arthritis: Methotrexate and beyond	8
Genome structure and genetic diversity in the Ebola virus	7
Three-dimensional perspective on ryanodine receptor mutations causing skeletal and cardiac muscle-related diseases	7
CFTR RNA- and DNA-based therapies	7
The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy	7
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle	7
MedXercise: a promising strategy to promote remyelination	7
Central and peripheral mechanisms involved in the control of GnRH neuronal function by metabolic factors	7
Novel treatments for dry eye syndrome	7
Circadian influence on inflammatory response during cardiovascular disease	7
Systemic inflammation after spinal cord injury: A review of biological evidence, related health risks, and potential therapies	7
Immune tolerance therapies for autoimmune diseases: Shifting the goalpost to cure	7
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus	7
Effects of protein glycation and protective mechanisms against glycative stress	7
Small molecule screening as an approach to encounter inefficient myelin repair	7
Regulation of pathway choice in DNA repair after double-strand breaks	7
Advances in tethered photopharmacology for precise optical control of signaling proteins	7
Targeting ferroptosis in the maintenance of mitochondrial homeostasis in the realm of septic cardiomyopathy	7
Advances in antiobesity mechanisms of capsaicin	7