Current Opinion in Pharmacology

Article	Citations
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?	97
Editorial Board	86
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies	82
Splice-switching as cancer therapy	63
Therapeutic hurdles in acute myeloid leukemia: Leukemic stem cells, inflammation and immune dysfunction	59
Lipid raft disruption as an opportunity for peripheral analgesia	58
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling	45
Recent advances in emerging PCOS therapies	44
The role of extracellular ATP in homeostatic immune cell migration	44
Gastrointestinal issue: Advances in gastrointestinal oncology	37
Editorial Board	36
Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases	35
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	33
Current status of hepatitis delta	33
Optic nerve regeneration: Potential treatment approaches	32
Optofluidic neural interfaces for in vivo photopharmacology	31
Artemisinins and their impact on inhibitory neurotransmission	30
Editorial overview: Special issue on “Rheumatology: Therapeutic advances for autoimmune and musculoskeletal diseases”	30
Photo-isomerizable tweezers to probe ionotropic receptor mechanisms	30
Pancreatic alpha cells and glucagon secretion: Novel functions and targets in glucose homeostasis	30
Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration	29
Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance	29
Advanced Microneedle Arrays for Transdermal Antibiotic Delivery	28
Editorial Board	27
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus	27

A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury	27
Animal models of cystic fibrosis in the era of highly effective modulator therapies	27
Three-dimensional culture models to study glioblastoma — current trends and future perspectives	27
Effects of functional electrical stimulation on muscle health after spinal cord injury	25
Exercise as a drug for glucose management and prevention in type 2 diabetes mellitus	25
Current state of CFTR modulators for treatment of Cystic Fibrosis	24
Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis	23
Plant-based vaccine research development against viral diseases with emphasis on Ebola virus disease: A review study	23
Muscle multiorgan crosstalk with MG53 as a myokine for tissue repair and regeneration	23
Editorial overview: An initiative toward Ebolavirus disease (EVD) free world: An edited special anti-infective issue on Ebola virus disease	22
Integrating single-cell transcriptomics and microcircuit computer modeling	22
Editorial Board	22
Targeting TRP channels for pain relief: A review of current evidence from bench to bedside	22
Therapeutic approaches in different congenital myopathies	22
Next-gen therapeutics to spare and expand beta-cell mass	22
Gene therapies for RyR1-related myopathies	22
Promising therapeutic approaches in pulmonary arterial hypertension	22
Treatment of severe alcoholic hepatitis: A systematic review	21
Very-low-calorie ketogenic diet: An alternative to a pharmacological approach to improve glycometabolic and gonadal profile in men with obesity	21
Drug development for the treatment of RyR1-related skeletal muscle diseases	21
Photopharmacological approaches for dissecting potassium channel physiology	21
Strategies to enhance anti-leukaemia immunotherapy	20
Oligonucleotide-based therapies for cystic fibrosis	19
Antihypertensive effect of soybean bioactive peptides: A review	19
Oncohistone-sculpted epigenetic mechanisms in pediatric brain cancer	19
Autophagy in neuronal physiology and disease	19
Lipids and lipid regulators in intraocular pressure homeostasis	19
Nutraceuticals in mental diseases — Bridging the gap between traditional use and modern pharmacology	18
Host membrane proteins in the HIV-induced membrane fusion: Role in pathogenesis and therapeutic potential of autoantibodies	18
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”	18
Non-alcoholic fatty liver disease: Current therapeutic options	17
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration	17
Photopharmacological control of cell signaling with photoswitchable lipids	17
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer	17
MicroRNA: A mediator of diet-induced cardiovascular protection	17
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development	17
Adoptive cell therapy for solid tumors: Chimeric antigen receptor T cells and beyond	16
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway	16
Challenges in Formulating Transdermal Systems for Treating Chronic Skin Infections	16
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?	16
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder	16
Purinergic signalling in graft-versus-host disease	16
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction	16
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation	16
Role of HSV-1 in Alzheimer's disease pathogenesis: A challenge for novel preventive/therapeutic strategies	15
Fluorescent chemigenetic actuators and indicators for use in living animals	15
CFTR RNA- and DNA-based therapies	15
NMR applications to GPCR recognition by peptide ligands	15
Targeting fibroblast-like synoviocytes in rheumatoid arthritis	15
Editorial overview: Introduction to the musculoskeletal section of current opinion in pharmacology	15

Effects of protein glycation and protective mechanisms against glycative stress	15
Light-activated receptor tyrosine kinases: Designs and applications	15
Editorial Board	15
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle	15
AI-driven GPCR analysis, engineering, and targeting	15
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?	14
Towards eradication of HBV: Treatment approaches and status of clinical trials	14
Novel treatments for dry eye syndrome	14
Advances in tethered photopharmacology for precise optical control of signaling proteins	14
Immune dysfunction after spinal cord injury – A review of autonomic and neuroendocrine mechanisms	14
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis	14
Novel approaches to CAR T cell target identification in acute myeloid leukemia	14
Targeting the endocannabinoid system for the management of low back pain	14
The expanding role of split protein complementation in opsin-free optogenetics	14
Caffeine consumption and schizophrenia: A highlight on adenosine receptor–independent mechanisms	13
Editorial Board	13
Is there still a place for radiotherapy in gastric cancer?	13
The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases	13
Anabolic–androgenic steroid abuse and testicular function in men; recent insights	13
Corrigendum to “Antihypertensive effect of soybean bioactive peptides: A review” [Curr Opin Pharmacol (62) (2022) 74–81]	13
Modulation of immune response in Ebola virus disease	13
Angiotensin II type 2 receptor signalling as a pain target: Bench, bedside and back-translation	13
Environmental toxicants, brown adipose tissue, and potential links to obesity and metabolic disease	13
Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming	13
Editorial Board	13
Innate and adaptive immune mechanisms regulating central nervous system remyelination	13
Auxiliary subunits of the AMPA receptor: The Shisa family of proteins	13
Physiological regulation of leptin as an integrative signal of reproductive readiness	13
Mechanisms of cardio-renal protection of sodium-glucose cotransporter-2 inhibitors	12
Treatment advances in antiphospholipid syndrome: 2022 update	12
Newly identified tumor suppressor functions of ING proteins	12
Targeting PKC in microglia to promote remyelination and repair in the CNS	12
Functional visualization and manipulation in the marmoset brain using viral vectors	12
Evolution of genetic testing supports precision medicine for caring Alzheimer's disease patients	12
EDITORIAL OVERVIEW: ADVANCED THERAPIES AND NEW TARGETS IN OCULAR DISEASES	12
Current and new targets for treating myositis	12
Probing function in 3D neuronal cultures: A survey of 3D multielectrode array advances	12
Recent insights into astrocytes as therapeutic targets for demyelinating diseases	12
Cancer synthetic vulnerabilities to protein arginine methyltransferase inhibitors	12
Repairing damaged lungs using regenerative therapy	12
Understanding the biology of volumetric muscle loss for an individualized exercise rehabilitation approach in breast cancer patients	11
A review of biosimilars for rheumatoid arthritis	11
Novel strategies to promote resolution of inflammation to treat lower extremity artery disease	11
Lipid-Based Nanocarriers in Topical Applications for Skin Infections	11
Corrigendum to ‘JAK inhibitors: Current position in treatment strategies for use in inflammatory bowel disease’	11
Impact of amino acids on microglial activation and CNS remyelination	11
Melatonin in neuroskeletal biology	11
Treatment of alcohol use disorder in patients with liver disease	11
Interrogating the function of GABAA receptors in the brain with optogenetic pharmacology	11
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe	10
New developments in treatments for systemic vasculitis	10
MedXercise: a promising strategy to promote remyelination	10
Biased signalling in analgesic research and development	10
Applications of chemogenetics in non-human primates	10
RAD51 paralogs: Expanding roles in replication stress responses and repair	10
From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches	10
The use of hormone stimulation in male infertility	10
Hormonal drugs for the treatment of endometriosis	10
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity	10
Recent developments and strategies of Ebola virus vaccines	10
Genome structure and genetic diversity in the Ebola virus	10
The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy	10
Gastrointestinal manifestations and SARS-CoV-2 infection	9
Making myelin regenerate: Factors to consider	9
Update on anti-fibrotic pharmacotherapies in skeletal muscle disease	9
Immunometabolic regulation of adipose tissue resident immune cells	9
Current treatment and molecular targets for axial spondyloarthritis: Evidence from randomized controlled trials	9
Editorial Board	9
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors	9
Testosterone therapy for prevention and reversal of type 2 diabetes in men with low testosterone	9
Optical control of Class A G protein-coupled receptors with photoswitchable ligands	9
Extracellular adenosine signaling in bone health and disease	9
Therapeutic opportunities for targeting cellular senescence in progressive multiple sclerosis	8
When and how to use direct oral anticoagulants in patients with advanced chronic liver disease?	8
Editorial Board	8
Novel therapeutic avenues for kisspeptin	8
Towards development of disease-modifying therapy for Alzheimer's disease using redox chemical biology pathways	8
Immune-mediated food reactions in irritable bowel syndrome	8
Editorial overview: Respiratory: Pulmonary pharmacology–The emergence of new treatments in pulmonary medicine is finally providing real therapeutic perspectives	8
Treatment approach to connective tissue disease-associated interstitial lung disease	8

Editorial overview: Immunometabolism	8
Reprogramming cell fates towards novel cancer immunotherapies	7
Microglia as therapeutic targets for central nervous system remyelination	7
Pharmacological modulation of GABAA receptors	7
Impacts of the Filoviridae family	7
In the heart and beyond: Mitochondrial dysfunction in heart failure with preserved ejection fraction (HFpEF)	7
COVID-19 in Latin America and the caribbean region: Symptoms and morbidities in the epidemiology of infection	7
The changing landscape of the cystic fibrosis lung environment: From the perspective of Pseudomonas aeruginosa	7
Alpha1-antitrypsin deficiency: New therapies on the horizon	7
Editorial: Nutraceuticals	7
Highland mate: Edible and functional foods in traditional medicine for the prevention and treatment of hypoxia-related symptoms	7
Treatments for COVID-19: Lessons from 2020 and new therapeutic options	7
Emerging strategies for treating gout	7
Breaking the barriers to remyelination in multiple sclerosis	7
Adipose tissue–heart crosstalk as a novel target for treatment of cardiometabolic diseases	7
Seeing is believing: Identifying remyelination in the central nervous system	7
Overview of CF lung pathophysiology	7
Impaired metabolism of oligodendrocyte progenitor cells and axons in demyelinated lesion and in the aged CNS	7