Current Opinion in Pharmacology

Article	Citations
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?	108
Editorial Board	100
Therapeutic hurdles in acute myeloid leukemia: Leukemic stem cells, inflammation and immune dysfunction	92
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling	74
Lipid raft disruption as an opportunity for peripheral analgesia	64
The role of extracellular ATP in homeostatic immune cell migration	59
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies	51
Recent advances in emerging PCOS therapies	50
Gastrointestinal issue: Advances in gastrointestinal oncology	47
Editorial Board	43
Optofluidic neural interfaces for in vivo photopharmacology	40
Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases	40
Photo-isomerizable tweezers to probe ionotropic receptor mechanisms	37
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	36
Pancreatic alpha cells and glucagon secretion: Novel functions and targets in glucose homeostasis	35
Emerging mutations in the SARS-CoV-2 variants and their role in antibody escape to small molecule-based therapeutic resistance	33
Optic nerve regeneration: Potential treatment approaches	33
Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration	33
Editorial overview: Special issue on “Rheumatology: Therapeutic advances for autoimmune and musculoskeletal diseases”	33
Advanced microneedle arrays for transdermal antibiotic delivery	33
Three-dimensional culture models to study glioblastoma — current trends and future perspectives	30
A review of emerging neuroprotective and neuroregenerative therapies in traumatic spinal cord injury	30
Editorial Board	29
Dyslipidemia and diabetes mellitus: Role of lipoprotein species and interrelated pathways of lipid metabolism in diabetes mellitus	29
Paeoniflorin is a promising natural monomer for neurodegenerative diseases via modulation of Ca2+ and ROS homeostasis	29

Effects of functional electrical stimulation on muscle health after spinal cord injury	28
Allogeneic double-negative T-cell therapy for acute myeloid leukemia	27
Plant-based vaccine research development against viral diseases with emphasis on Ebola virus disease: A review study	26
Therapeutic approaches in different congenital myopathies	26
Current state of CFTR modulators for treatment of Cystic Fibrosis	26
Editorial Board	26
Animal models of cystic fibrosis in the era of highly effective modulator therapies	26
Integrating single-cell transcriptomics and microcircuit computer modeling	25
Editorial overview: An initiative toward Ebolavirus disease (EVD) free world: An edited special anti-infective issue on Ebola virus disease	24
Gene therapies for RyR1-related myopathies	24
Targeting TRP channels for pain relief: A review of current evidence from bench to bedside	24
Next-gen therapeutics to spare and expand beta-cell mass	23
Oligonucleotide-based therapies for cystic fibrosis	23
Lipids and lipid regulators in intraocular pressure homeostasis	22
Strategies to enhance anti-leukaemia immunotherapy	21
Photopharmacological approaches for dissecting potassium channel physiology	21
Oncohistone-sculpted epigenetic mechanisms in pediatric brain cancer	21
Very-low-calorie ketogenic diet: An alternative to a pharmacological approach to improve glycometabolic and gonadal profile in men with obesity	21
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration	20
Antihypertensive effect of soybean bioactive peptides: A review	20
Host membrane proteins in the HIV-induced membrane fusion: Role in pathogenesis and therapeutic potential of autoantibodies	20
Treatment of severe alcoholic hepatitis: A systematic review	20
Drug development for the treatment of RyR1-related skeletal muscle diseases	20
Autophagy in neuronal physiology and disease	20
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer	19
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”	19
Non-alcoholic fatty liver disease: Current therapeutic options	19
Nutraceuticals in mental diseases — Bridging the gap between traditional use and modern pharmacology	19
MicroRNA: A mediator of diet-induced cardiovascular protection	18
Photopharmacological control of cell signaling with photoswitchable lipids	18
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder	18
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation	18
Challenges in formulating transdermal systems for treating chronic skin infections	17
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction	17
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?	17
Light-activated receptor tyrosine kinases: Designs and applications	17
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway	17
Purinergic signalling in graft-versus-host disease	17
Targeting fibroblast-like synoviocytes in rheumatoid arthritis	16
Editorial overview: Introduction to the musculoskeletal section of current opinion in pharmacology	16
AI-driven GPCR analysis, engineering, and targeting	16
Editorial Board	16
Role of HSV-1 in Alzheimer's disease pathogenesis: A challenge for novel preventive/therapeutic strategies	16
CFTR RNA- and DNA-based therapies	16
Fluorescent chemigenetic actuators and indicators for use in living animals	16
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?	16
Immune dysfunction after spinal cord injury – A review of autonomic and neuroendocrine mechanisms	15
Towards eradication of HBV: Treatment approaches and status of clinical trials	15
Effects of protein glycation and protective mechanisms against glycative stress	15
NMR applications to GPCR recognition by peptide ligands	15

Advances in tethered photopharmacology for precise optical control of signaling proteins	15
Spinal and bulbar muscular atrophy: From molecular pathogenesis to pharmacological intervention targeting skeletal muscle	15
Novel approaches to CAR T cell target identification in acute myeloid leukemia	15
TMEM16A (ANO1) as a therapeutic target in cystic fibrosis	15
Targeting the endocannabinoid system for the management of low back pain	15
The expanding role of split protein complementation in opsin-free optogenetics	15
Editorial Board	14
Novel treatments for dry eye syndrome	14
Innate and adaptive immune mechanisms regulating central nervous system remyelination	14
Editorial Board	14
Modulation of immune response in Ebola virus disease	14
Corrigendum to “Antihypertensive effect of soybean bioactive peptides: A review” [Curr Opin Pharmacol (62) (2022) 74–81]	14
Angiotensin II type 2 receptor signalling as a pain target: Bench, bedside and back-translation	13
Is there still a place for radiotherapy in gastric cancer?	13
Newly identified tumor suppressor functions of ING proteins	13
Current and new targets for treating myositis	13
Editorial overview: Advanced therapies and new targets in ocular diseases	13
Caffeine consumption and schizophrenia: A highlight on adenosine receptor–independent mechanisms	13
Targeting PKC in microglia to promote remyelination and repair in the CNS	13
Environmental toxicants, brown adipose tissue, and potential links to obesity and metabolic disease	13
Mechanisms of cardio-renal protection of sodium-glucose cotransporter-2 inhibitors	13
Physiological regulation of leptin as an integrative signal of reproductive readiness	13
The molecular link between oxidative stress, insulin resistance, and type 2 diabetes: A target for new therapies against cardiovascular diseases	13
Dysregulation of immune checkpoint proteins in hepatocellular carcinoma: Impact on metabolic reprogramming	13
Anabolic–androgenic steroid abuse and testicular function in men; recent insights	13
Recent insights into astrocytes as therapeutic targets for demyelinating diseases	13
Evolution of genetic testing supports precision medicine for caring Alzheimer's disease patients	12
A review of biosimilars for rheumatoid arthritis	12
Treatment advances in antiphospholipid syndrome: 2022 update	12
Precision medicine and immunotherapeutic approaches for relapsed/refractory paediatric acute myeloid leukaemia	12
Treatment of alcohol use disorder in patients with liver disease	12
Lipid-based nanocarriers in topical applications for skin infections	12
Novel strategies to promote resolution of inflammation to treat lower extremity artery disease	12
From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches	12
Melatonin in neuroskeletal biology	12
Probing function in 3D neuronal cultures: A survey of 3D multielectrode array advances	12
Functional visualization and manipulation in the marmoset brain using viral vectors	12
Impact of amino acids on microglial activation and CNS remyelination	12
Interrogating the function of GABAA receptors in the brain with optogenetic pharmacology	12
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe	11
RAD51 paralogs: Expanding roles in replication stress responses and repair	11
Biased signalling in analgesic research and development	11
Health benefits of spices in individuals with chemotherapeutic drug-induced cardiotoxicity	11
Applications of chemogenetics in non-human primates	11
Colloidal drug delivery systems for infectious diseases of skin	11
Hormonal drugs for the treatment of endometriosis	11
New developments in treatments for systemic vasculitis	11
Recent developments and strategies of Ebola virus vaccines	11
MedXercise: a promising strategy to promote remyelination	11
Extracellular adenosine signaling in bone health and disease	10
Update on anti-fibrotic pharmacotherapies in skeletal muscle disease	10
The use of hormone stimulation in male infertility	10
Editorial Board	10
Optical control of Class A G protein-coupled receptors with photoswitchable ligands	10
The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy	10
Genome structure and genetic diversity in the Ebola virus	10
Making myelin regenerate: Factors to consider	9
Spatiotemporal GPCR signaling illuminated by genetically encoded fluorescent biosensors	9
Editorial overview: Immunometabolism	9
Therapeutic opportunities for targeting cellular senescence in progressive multiple sclerosis	9
Current treatment and molecular targets for axial spondyloarthritis: Evidence from randomized controlled trials	9
Gastrointestinal manifestations and SARS-CoV-2 infection	9
Novel therapeutic avenues for kisspeptin	9
When and how to use direct oral anticoagulants in patients with advanced chronic liver disease?	9
Editorial overview: Respiratory: Pulmonary pharmacology–The emergence of new treatments in pulmonary medicine is finally providing real therapeutic perspectives	9
Immune-mediated food reactions in irritable bowel syndrome	9
Towards development of disease-modifying therapy for Alzheimer's disease using redox chemical biology pathways	8
Treatment approach to connective tissue disease-associated interstitial lung disease	8
Adipose tissue–heart crosstalk as a novel target for treatment of cardiometabolic diseases	8
Seeing is believing: Identifying remyelination in the central nervous system	8
Treatments for COVID-19: Lessons from 2020 and new therapeutic options	8
Breaking the barriers to remyelination in multiple sclerosis	8
Microglia as therapeutic targets for central nervous system remyelination	8
The changing landscape of the cystic fibrosis lung environment: From the perspective of Pseudomonas aeruginosa	8
Impacts of the Filoviridae family	8
Editorial Board	8
Reprogramming cell fates towards novel cancer immunotherapies	8
Editorial: Nutraceuticals	8
Highland mate: Edible and functional foods in traditional medicine for the prevention and treatment of hypoxia-related symptoms	8
COVID-19 in Latin America and the caribbean region: Symptoms and morbidities in the epidemiology of infection	8

Impaired metabolism of oligodendrocyte progenitor cells and axons in demyelinated lesion and in the aged CNS	7
In the heart and beyond: Mitochondrial dysfunction in heart failure with preserved ejection fraction (HFpEF)	7
Editorial Board	7
Overview of CF lung pathophysiology	7
Routine neoadjuvant chemotherapy for all patients with resectable pancreatic ductal adenocarcinoma? A review of the evidence	7
Current pharmacological treatment of hepatocellular carcinoma	7
Emerging strategies for treating gout	7
Editorial Board	7