OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Pharmacology is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Metabolic comorbidities of adrenal insufficiency: Focus on steroid replacement therapy and chronopharmacology	88
Editorial Board	79
Editorial overview: Immune regulation and cancers	73
Established and novel human translational models to advance cystic fibrosis research, drug discovery, and optimize CFTR-targeting therapeutics	57
Editorial Board	57
Routine neoadjuvant chemotherapy for all patients with resectable pancreatic ductal adenocarcinoma? A review of the evidence	55
Editorial overview – 2022 respiratory issue: Cystic fibrosis pathophysiology, models, and novel therapies	43
Editorial Board	42
Lipid raft disruption as an opportunity for peripheral analgesia	41
Editorial Board	41
Editorial Board	36
Non-alcoholic fatty liver disease: Current therapeutic options	33
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling	32
MicroRNA: A mediator of diet-induced cardiovascular protection	32
Dietary serine supplementation: Friend or foe?	31
Tropical fruits from Australia as potential treatments for metabolic syndrome	31
Elexacaftor–tezacaftor–ivacaftor: The new paradigm to treat people with cystic fibrosis with at least one p.Phe508del mutation	30
Splice-switching as cancer therapy	30
Pharmacologic treatment of gastroparesis: What is (still) on the horizon?	29
Stress, kisspeptin, and functional hypothalamic amenorrhea	29
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer	29
Organotypic human ex vivo models for coronavirus disease 2019 research and drug development	28
New CARs on and off the road: challenges and new developments in CAR-T cell therapy	28
Quantitative assessment of volumetric muscle loss: Dual-energy X-ray absorptiometry and ultrasonography	28
Current pharmacological treatment of hepatocellular carcinoma	27

Host membrane proteins in the HIV-induced membrane fusion: Role in pathogenesis and therapeutic potential of autoantibodies	27
Interrogating the function of GABAA receptors in the brain with optogenetic pharmacology	25
Nutraceuticals use and type 2 diabetes mellitus	25
Metabolic regulation of tissue-resident memory CD8+ T cells	25
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?	24
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration	24
Nutraceuticals in mental diseases — Bridging the gap between traditional use and modern pharmacology	23
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies	22
Balancing Genome Integrity and Carcinogenesis: Insights into DNA Damage Response, Repair Pathways, and Cancer Therapies	21
Emerging drugs for the treatment of primary sclerosing cholangitis	21
Circulating factors that influence the central nervous system remyelination	21
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”	21
Targeting the soluble epoxide hydrolase pathway as a novel therapeutic approach for the treatment of pain	21
Drug effects on neuropeptides and their receptors: Big hopes but moderate success in the treatment of chronic pain	21
Recent advances in emerging PCOS therapies	21
The active kinome: The modern view of how active protein kinase networks fit in biological research	20
Corrigendum to ‘JAK inhibitors: Current position in treatment strategies for use in inflammatory bowel disease’	20
Photopharmacological control of cell signaling with photoswitchable lipids	20
Photoswitchable allosteric modulators for metabotropic glutamate receptors	19
The blood pressure lowering effects of glucagon-like peptide-1 receptor agonists: A mini-review of the potential mechanisms	19
The 2013–2016 Ebola virus disease outbreak in West Africa	19
Beyond the AMPA receptor: Diverse roles of SynDIG/PRRT brain-specific transmembrane proteins at excitatory synapses	19
Integrating network pharmacology: The next-generation approach in ocular drug discovery	19
New developments in treatments for systemic vasculitis	18
The role of extracellular ATP in homeostatic immune cell migration	18
Impact of amino acids on microglial activation and CNS remyelination	18
Disease-modifying therapies in short bowel syndrome	18
Novel strategies to promote resolution of inflammation to treat lower extremity artery disease	18
Interventional functional diagnostics in gastrointestinal endoscopy: Combining diagnostic and therapeutic tools in the endoscopy suite with the functional lumen imaging probe	18
Role of metformin and other metabolic drugs in the prevention and therapy of endocrine-related cancers	18
Current status of hepatitis delta	17
Editorial Board	17
Editorial Board	17
The regulatory roles of dietary fibers on host health via gut microbiota-derived short chain fatty acids	17
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder	17
Cancer 2021: New therapeutic approaches for the treatment of cancer — building on advances in cancer biology and the molecular genetics of cancer	16
Gastrointestinal issue: Advances in gastrointestinal oncology	16
Editorial overview: Endocrine and metabolic diseases (2023)	16
Editorial Board	16
Targeting intramuscular adipose tissue expansion to preserve contractile function in volumetric muscle loss: A potentially novel therapy?	15
Optofluidic neural interfaces for in vivo photopharmacology	15
Editorial overview: Neuroscience: Advances in the field	15
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction	15
Editorial Board	15
Artemisinins and their impact on inhibitory neurotransmission	15
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?	15
Practical application of breath tests in disorders of gut–brain interaction	14
Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss	14
From serendipity to rational drug design in brain disorders: in silico, in vitro, and in vivo approaches	14
Optic nerve regeneration: Potential treatment approaches	14

Technological advancements to study cellular signaling pathways in inherited retinal degenerative diseases	14
Nonsteroidal mineralcorticoid receptor antagonists: Novel therapeutic implication in the management of patients with type 2 diabetes	14
The complement pathway as a therapeutic target for neovascular age-related macular degeneration-mediated subretinal fibrosis	14
Corticosteroids and circadian rhythms in the cardiovascular system	14
Photo-isomerizable tweezers to probe ionotropic receptor mechanisms	14
How organoids can improve personalized treatment in patients with gastro-esophageal tumors	13
A computational overview on phylogenetic characterization, pathogenic mutations, and drug targets for Ebola virus disease	13
Remyelinating strategies: What can be learned from normal brain development	13
Adoptive cell therapy for solid tumors: Chimeric antigen receptor T cells and beyond	13
Analgesic potential of voltage gated sodium channel modulators for the management of pain	13
Targeting the altered duodenal microenvironment in functional dyspepsia	13
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation	13
RAD51 paralogs: Expanding roles in replication stress responses and repair	13
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	13
Light-activated receptor tyrosine kinases: Designs and applications	13
Photopharmacology for vision restoration	13
Purinergic signalling in graft-versus-host disease	13
Therapeutic strategies for treating juvenile idiopathic arthritis	13
Corrigendum to “Metformin: Still the sweet spot for CV protection in diabetes?” [Curr Opin Pharmacol 54 (2020) 202–208]	13