OOIR: Observatory of International Research

Papers

(The TQCC of Current Opinion in Pharmacology is 13. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Editorial Board	137
Recent advances in emerging PCOS therapies	93
Lipid raft disruption as an opportunity for peripheral analgesia	67
Corrigendum to “From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling” [COPHAR 76 (2024) 102458]	60
Advances in pain therapeutics: Targets, mechanisms, and translational frontiers	55
Lipidomics-driven insights into acupuncture mechanisms: From dynamic signaling networks to multi-dimensional regulations	45
Targeting strategies and immune regulatory mechanisms of CAR-macrophages in the treatment of osteosarcoma	44
Therapeutic hurdles in acute myeloid leukemia: Leukemic stem cells, inflammation and immune dysfunction	44
The role of extracellular ATP in homeostatic immune cell migration	43
Native botulinum toxin type A vs. redesigned botulinum toxins in pain: What did we learn so far?	38
From “contraindicated” to “first line” – Current mechanistic insights beyond canonical β-receptor signaling	37
The P2X7 purinoceptor in pathogenesis and treatment of dystrophino- and sarcoglycanopathies	35
Editorial Board	33
Gastrointestinal issue: Advances in gastrointestinal oncology	33
CRISPR-Cas9 in acute myeloid leukaemia: Current state-of-art and future perspectives	32
Auricular stimulation therapy: An evidence-based practice strategy for depression	31
Considerations for individualized first-line systemic treatment in advanced hepatocellular carcinoma	30
Optic nerve regeneration: Potential treatment approaches	30
Editorial overview: Special issue on “Rheumatology: Therapeutic advances for autoimmune and musculoskeletal diseases”	28
Pharmaceutical therapies targeting autophagy for the treatment of age-related macular degeneration	28
Editorial Board	28
Advanced microneedle arrays for transdermal antibiotic delivery	25
Editorial Board	25
Editorial Board	25
Innovative pipeline therapeutics in inflammatory bowel disease: Anti-tumor necrosis factor-like ligand 1A and bispecific antibodies	24

Animal models of cystic fibrosis in the era of highly effective modulator therapies	23
Allogeneic double-negative T-cell therapy for acute myeloid leukemia	23
Current state of CFTR modulators for treatment of Cystic Fibrosis	22
Transcutaneous electrical nerve stimulation and opioid analgesia: Exploring a potential synergistic relationship	22
Gene therapies for RyR1-related myopathies	22
Therapeutic approaches in different congenital myopathies	21
Valproic acid: Mechanistic insights into neuronal actions, epigenetic modulation, and clinical risk	21
Riluzole in neuroinflammation and neurodegeneration: Mechanistic insights and experimental validation	21
Targeting TRP channels for pain relief: A review of current evidence from bench to bedside	21
Strategies to enhance anti-leukaemia immunotherapy	21
Oligonucleotide-based therapies for cystic fibrosis	20
Drug development for the treatment of RyR1-related skeletal muscle diseases	20
Oncohistone-sculpted epigenetic mechanisms in pediatric brain cancer	20
Lipids and lipid regulators in intraocular pressure homeostasis	20
Estrogen related receptor alpha: Potential modulator of age-related macular degeneration	19
The role of plant-derived compounds in anti-obesity drug discovery: A molecular perspective	19
Shaping DNA damage responses: Therapeutic potential of targeting telomeric proteins and DNA repair factors in cancer	18
Smart solutions for tough infections: The rise of next-gen transdermal drug delivery	18
Acupuncture for depression: Decoding neuroimmune crosstalk and targeting anti-inflammatory mechanisms	17
Editorial overview: “Purinergic immune cell regulation reveals novel pharmacological targets”	17
NanoPhyto formulations: A promising approach for targeted therapy of gastrointestinal infections, clinical advancements, and future perspectives	17
Antibiotics, the microbiome and gastrointestinal cancers: A causal interference?	16
Highlighting vulnerabilities in the alternative lengthening of telomeres pathway	16
Purinergic signalling in graft-versus-host disease	16
Functional role of the ER stress transducer IRE1α in CF airway epithelial inflammation	16
Challenges in formulating transdermal systems for treating chronic skin infections	16
Targeting the NRF2 pathway: A promising approach for corneal endothelial dysfunction	16
Editorial overview: COVID-19 therapy: From lung disease to systemic disorder	16
TMEM16A regulates MUC5AC production in airway diseases: A comprehensive review	15
Advancements in targeted therapies for acute myeloid leukemia	15
Personalizing nutrition therapy in inflammatory bowel disease: Practical applications and review of the latest studies	14
Editorial overview: Introduction to the musculoskeletal section of current opinion in pharmacology	14
Targeting fibroblast-like synoviocytes in rheumatoid arthritis	14
Editorial Board	14
Targeting the endocannabinoid system for the management of low back pain	14
PRRT for higher-grade neuroendocrine neoplasms: What is still acceptable?	13
NMR applications to GPCR recognition by peptide ligands	13
Effects of protein glycation and protective mechanisms against glycative stress	13
Revolutionizing UC monitoring: The emerging role of intestinal ultrasound	13