OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Immunology is 16. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Mechanisms of SARS-CoV-2 Transmission and Pathogenesis	769
Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses	602
Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity	348
The Role of Astrocytes in CNS Inflammation	265
A Potential Role of Interleukin 10 in COVID-19 Pathogenesis	218
Organoid Models of Tumor Immunology	210
Inflammation and Skeletal Muscle Regeneration: Leave It to the Macrophages!	198
Turning cold tumors hot: from molecular mechanisms to clinical applications	179
Macrophage diversity in cancer revisited in the era of single-cell omics	159
The ‘cytokine storm’: molecular mechanisms and therapeutic prospects	155
Coronaviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines	149
Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses	145
Microglia and Astrocytes in Disease: Dynamic Duo or Partners in Crime?	145
The Contribution of Epigenetics to Cancer Immunotherapy	136
T Cells: Warriors of SARS-CoV-2 Infection	136
NF-κB: blending metabolism, immunity, and inflammation	128
CRAC Channels and Calcium Signaling in T Cell-Mediated Immunity	118
To Kill a Microglia: A Case for CSF1R Inhibitors	117
Sialoglycans and Siglecs Can Shape the Tumor Immune Microenvironment	115
Tolerogenic Dendritic Cells in Autoimmunity and Inflammatory Diseases	113
Neuroimmune Connections in Aging and Neurodegenerative Diseases	109
Tissue-Specific Features of Innate Lymphoid Cells	104
Improving Vaccine-Induced Immunity: Can Baseline Predict Outcome?	93
VISTA: A Mediator of Quiescence and a Promising Target in Cancer Immunotherapy	90
AID in Antibody Diversification: There and Back Again	89

Cytokine-skewed Tfh cells: functional consequences for B cell help	88
Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (TFH)	83
Dual Nature of Type I Interferons in SARS-CoV-2-Induced Inflammation	83
Early clues regarding the pathogenesis of long-COVID	79
Opportunities for Small Molecules in Cancer Immunotherapy	78
Unraveling B cell trajectories at single cell resolution	78
Structural Basis of SARS-CoV-2 and SARS-CoV Antibody Interactions	77
How Neutrophils Meet Their End	76
Tissue-resident macrophages: guardians of organ homeostasis	76
Immune imprinting and SARS-CoV-2 vaccine design	74
A20 and Cell Death-driven Inflammation	69
Polyamines and Kynurenines at the Intersection of Immune Modulation	68
Decoding the Heterogeneity of Human Dendritic Cell Subsets	68
Transcription Factor Bhlhe40 in Immunity and Autoimmunity	66
Single B cell technologies for monoclonal antibody discovery	64
Monocyte Regulation in Homeostasis and Malignancy	64
CD4+ T cells that help B cells – a proposal for uniform nomenclature	63
Predicting and Preventing Immune Checkpoint Inhibitor Toxicity: Targeting Cytokines	61
RORγt protein modifications and IL-17-mediated inflammation	60
The Role of TGFβ Signaling in Microglia Maturation and Activation	60
Sarcoidosis and the mTOR, Rac1, and Autophagy Triad	56
The Speckled Protein (SP) Family: Immunity’s Chromatin Readers	54
Emerging mechanisms of immunocoagulation in sepsis and septic shock	52
Teaching Old Dogs New Tricks? The Plasticity of Lung Alveolar Macrophage Subsets	51
Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses	51
The cholesterol pathway: impact on immunity and cancer	51
Cardiac Mast Cells: Underappreciated Immune Cells in Cardiovascular Homeostasis and Disease	49
Lactic acid and lactate: revisiting the physiological roles in the tumor microenvironment	49
Hypoxia and HIF-1 as key regulators of gut microbiota and host interactions	48
Circadian Influences of Diet on the Microbiome and Immunity	48
Harnessing IL-15 signaling to potentiate NK cell-mediated cancer immunotherapy	48
Sodium and its manifold impact on our immune system	47
Combining Antivirals and Immunomodulators to Fight COVID-19	43
Activation and Suppression of Group 3 Innate Lymphoid Cells in the Gut	43
LFA-1 in T cell priming, differentiation, and effector functions	43
The Complement C5a-C5aR1 GPCR Axis in COVID-19 Therapeutics	43
Rewriting History: Epigenetic Reprogramming of CD8+ T Cell Differentiation to Enhance Immunotherapy	43
Diversity and Function of Glial Cell Types in Multiple Sclerosis	42
Context-Dependent Glioblastoma–Macrophage/Microglia Symbiosis and Associated Mechanisms	42
Type IIA Secreted Phospholipase A2 in Host Defense against Bacterial Infections	40
Overcoming Immune Checkpoint Blockade Resistance via EZH2 Inhibition	40
Helper-like Innate Lymphoid Cells in Humans and Mice	40
Differential roles of interferons in innate responses to mucosal viral infections	39
Complement Factors in COVID-19 Therapeutics and Vaccines	37
Lymph node fibroblastic reticular cells steer immune responses	37
New insights into TCR β-selection	36
Immunological Features of Non-neuronal Brain Cells: Implications for Alzheimer’s Disease Immunotherapy	35
Investigating Microglia in Health and Disease: Challenges and Opportunities	35
Host immunity and cellular responses to bacterial outer membrane vesicles	34
Maternal inflammation and its ramifications on fetal neurodevelopment	34

K63 ubiquitination in immune signaling	33
NF-κB and Extrinsic Cell Death Pathways – Entwined Do-or-Die Decisions for T cells	33
SARS Coronavirus Redux	33
Communication, construction, and fluid control: lymphoid organ fibroblastic reticular cell and conduit networks	32
The tetraspan MS4A family in homeostasis, immunity, and disease	32
Tissue-specific differentiation of CD8+ resident memory T cells	31
Succinate Receptor 1: An Emerging Regulator of Myeloid Cell Function in Inflammation	30
Cell Cycle Regulation Meets Tumor Immunosuppression	30
Unleashing TNF cytotoxicity to enhance cancer immunotherapy	30
Decoding the dynamics of multilayered stochastic antiviral IFN-I responses	30
Metabolic regulation of the cancer-immunity cycle	29
NAD+ in COVID-19 and viral infections	28
OTULIN in NF-κB signaling, cell death, and disease	28
Enemy or ally? Fasting as an essential regulator of immune responses	28
Neuroimmune cleanup crews in brain injury	28
miRNA-Based Therapies in B Cell Non-Hodgkin Lymphoma	27
C3-targeted therapy in periodontal disease: moving closer to the clinic	27
NLRP3 inflammasomes that induce antitumor immunity	27
Remnant Epitopes Generating Autoimmunity: From Model to Useful Paradigm	27
Systemic Immunoregulatory Consequences of Gut Commensal Translocation	26
Hematopoiesis in numbers	25
Guillain-Barré syndrome: expanding the concept of molecular mimicry	25
Developing pan-β-coronavirus vaccines against emerging SARS-CoV-2 variants of concern	25
Early Events Triggering the Initiation of a Type 2 Immune Response	25
T Cell Development: Old Tales Retold By Single-Cell RNA Sequencing	24
‘Rinse and Replace’: Boosting T Cell Turnover To Reduce HIV-1 Reservoirs	24
Understanding mast cell heterogeneity at single cell resolution	24
Lighting up the tumor fire with low-dose irradiation	23
Understanding Normal and Malignant Human Hematopoiesis Using Next-Generation Humanized Mice	23
Emerging roles of Dectin-1 in noninfectious settings and in the CNS	22
Reimagining antibody-dependent cellular cytotoxicity in cancer: the potential of natural killer cell engagers	22
ATM: Translating the DNA Damage Response to Adaptive Immunity	21
The potential role of HIV-1 latency in promoting neuroinflammation and HIV-1-associated neurocognitive disorder	21
Afucosylated IgG responses in humans – structural clues to the regulation of humoral immunity	21
BCG vaccination induces cross-protective immunity against pathogenic microorganisms	21
Transcriptional Control of Mature B Cell Fates	21
Lipid regulation of NLRP3 inflammasome activity through organelle stress	20
The Paradoxical Roles of Inflammation during PD-1 Blockade in Cancer	20
The NLRP3 inflammasome: regulation by metabolic signals	20
Tick host immunity: vector immunomodulation and acquired tick resistance	19
TCR-sequencing in cancer and autoimmunity: barcodes and beyond	19
Macrophage immunotherapy: overcoming impediments to realize promise	19
Modeling Potential Autophagy Pathways in COVID-19 and Sarcoidosis	19
How metabolism bridles cytotoxic CD8+ T cells through epigenetic modifications	19
The heightened importance of the microbiome in cancer immunotherapy	19
ADAR1 and ZBP1 in innate immunity, cell death, and disease	19
Parkinson's disease: connecting mitochondria to inflammasomes	18
Lymph node stromal cells: subsets and functions in health and disease	18
Genes, Environments, and Phenotypic Plasticity in Immunology	17
NF-κB dynamics in the language of immune cells	17
Natural resistance against infections: focus on COVID-19	17
Noncanonical Functions of Antibodies	17
Tumor microenvironment metabolites directing T cell differentiation and function	17
Breadth of Antibody Responses during Influenza Virus Infection and Vaccination	17
Cell-intrinsic view of the aryl hydrocarbon receptor in tumor immunity	16
Targeting butyrophilins for cancer immunotherapy	16
SARS-CoV-2 vaccination washes away original antigenic sin	16
Synovial macrophages: from ordinary eaters to extraordinary multitaskers	16
Programming cytomegalovirus as an HIV vaccine	16
Developing cultural humility in immunology and STEMM mentoring	16
Noradrenergic Signaling and Neuroinflammation Crosstalk Regulate Toxoplasma gondii-Induced Behavioral Changes	16
Testicular macrophages: development and function in health and disease	16
Protein Arginine Methyltransferase 5 in T Lymphocyte Biology	16
Type 1 conventional dendritic cells: ontogeny, function, and emerging roles in cancer immunotherapy	16