Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	218
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Subscription and Copyright Information	188
Advisory Board and Contents	187
Stories in Molecular Medicine December 2021	184
Advisory Board and Contents	152
Subscription and Copyright Information	144
Advisory Board and Contents	133
Subscription and Copyright Information	122
Subscription and Copyright Information	118
Pre-eclampsia: Challenges for Nanomedicine Development in Pregnancy	113
Neutrophils and extracellular traps in crystal-associated diseases	108
m6A and beyond: RNA modifications shaping angiogenesis	105
Fc-optimized checkpoint antibodies for cancer immunotherapy	105
Opportunities and challenges for biomarker discovery using electronic health record data	97
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	97
Beneath the radar: immune-evasive cell sources for stroke therapy	94
Pushing the boundaries of brain organoids to study Alzheimer’s disease	94
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	90
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	88
d-Amino acids: new clinical pathways for brain diseases	82
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	77
Consideration of the importance of measuring thermal discomfort in biomedical research	76
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	75
Subscription and Copyright Information	73

Stories in Molecular Medicine November 2021	72
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	67
Insights from HIV-1 vaccine and passive immunization efficacy trials	67
Brain-specific regulatory T cell expansion limits cognitive decline	66
iPSCs and DRGs: stepping stones to new pain therapies	63
Hormesis as an adaptive response to infection	63
Engineering cytokines for tumor-targeting and selective T cell activation	63
Acquired resistance to immunotherapy in solid tumors	62
Erythropoietic protoporphyrias: updates and advances	61
Cell-free circulating tumor DNA profiling in cancer management	60
Microbes and mood: innovative biomarker approaches in depression	59
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	50
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	50
Advisory Board and Contents	50
RNA immunotherapy: revolutionizing cancer and autoimmune disease treatments	49
Molecular mechanisms in the pathogenesis of dengue infections	49
Emerging roles of cyclin-dependent kinase 7 in health and diseases	47
Keratinocytes: new perspectives in inflammatory skin diseases	47
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	44
Amyloid and collagen templates in aortic valve calcification	44
Epigenetic regulation in intervertebral disc degeneration	43
Three ‘E’ challenges for siRNA drug development	43
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	43
In Utero Gene Therapy: Progress and Challenges	43
Promoting proteostasis by cAMP/PKA and cGMP/PKG	43
Significant challenges to translating breakthrough science in Mexico	42
Advisory Board and Contents	42
Advisory Board and Contents	42
Shining a light on comorbidities	41
Roadmap for developing biologically inspired therapeutics for genetic brain disorders	40
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Subscription and Copyright Information	40
Mitigating age-related somatic mutation burden	39
Clinical implications of vitamin B12 as redox-active cofactor	39
The endoplasmic reticulum proteostasis network and bone disease	38
SOX17: escape route from immune destruction in early CRC	38
Pathogenic mechanisms in genetically defined Ehlers–Danlos syndromes	37
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation	37
CircRNA perspective: new strategies for RNA therapy	37
Science around the world	36
Antibody signatures in inflammatory bowel disease: current developments and future applications	36
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Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	36
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	35
Time-restricted feeding and Alzheimer’s disease: you are when you eat	35
The bleeding edge: broadening horizons for hematopoietic stem cell therapies	34
Targeting mitochondrial transfer as a promising therapeutic strategy	34
Molecular disease mechanisms of human antineuronal monoclonal autoantibodies	33
Saving eyesight, one gene at a time	32
IL-15 in CAR engineering: striking an efficacy–safety balance	32

Translation of gene therapy strategies for amyotrophic lateral sclerosis	32
Naked mole-rats: at the heart of it	32
Skin senescence: mechanisms and impact on whole-body aging	31
The emerging Janus face of SVEP1 in development and disease	31
Intestinal mucus barrier: a missing piece of the puzzle in food allergy	30
Advisory Board and Contents	30
Focused ultrasound gene delivery for the treatment of neurological disorders	30
Maternal obesity: new placental paradigms unfolded	30
Science around the world	29
Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach	28
Advisory Board and Contents	28
ABC transporters: human disease and pharmacotherapeutic potential	27
Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery	27
Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health	27
Fibroblasts in AKI: small army, big help	27
Cystic fibrosis at a glance: from disease mechanism to therapy	27
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes	27
Advisory Board and Contents	26
Translational opportunities emerge from genetic influences on health	25
Incorporating placental pathology into clinical care and research	25
Autoantibodies as drivers of neuropathic pain	25
Clock-modulated checkpoints in time-restricted eating	25
Gasdermins in pyroptosis, inflammation, and cancer	25
Insights from myalgic encephalomyelitis/chronic fatigue syndrome may help unravel the pathogenesis of postacute COVID-19 syndrome	25
Splicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer	25
Biodiversity: the overlooked source of human health	24
Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes	24
Leveraging cellular mechano-responsiveness for cancer therapy	24
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	23
Advisory Board and Contents	23
Subscription and Copyright Information	23
Subscription and Copyright Information	23
Advisory Board and Contents	23
The global human gut microbiome: genes, lifestyles, and diet	23
Advisory Board and Contents	22
Stratum corneum as polymer sheet: concept and cornification processes	22
Human dopaminergic system in the exercise-cognition link	22
iPSC-derived models for anorexia nervosa research	22
Dissecting mechanisms of fecal microbiota transplantation efficacy in disease	22
Novel universal vaccines to mitigate emerging avian influenza viruses	22
Molecular basis and clinical implications of HIFs in cardiovascular diseases	22
Subscription and Copyright Information	21
Subscription and Copyright Information	21
Circadian molecular clock disruption in chronic pulmonary diseases	21
Advisory Board and Contents	21
TIM-3 blockade: immune and targeted therapy in DIPG	21
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	21
mRNA vaccine platforms to prevent bacterial infections	21
Vitiligo: advances in pathophysiology research and treatment development	20
Autoimmune diseases and cardiovascular risk	20
AAV capsid design: A Goldilocks challenge	19
Understanding the tuberculosis granuloma: the matrix revolutions	19
Vaccine-based immunotherapy and related preclinical models for glioma	19
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	19
Copy number alterations: a catastrophic orchestration of the breast cancer genome	18
Thymic stroma and TFII-I: towards new targeted therapies	18
Asthma exacerbations: the Achilles heel of asthma care	18
Advisory Board and Contents	18
Organ-specific aging in the plasma proteome predicts disease	18
HPV integration and cervical cancer: a failed evolutionary viral trait	18
Common mechanisms in pediatric acute liver failure	18
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	18
Staging of Alzheimer’s disease: past, present, and future perspectives	18
Telomere biology disorders: time for moving towards the clinic?	17
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	17
Tertiary lymphoid structures in the central nervous system	17
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	16
The dual role of the TSC complex in cancer	16
Primary cilia shape hallmarks of health and aging	16
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	16
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	16
There is nothing as inconsistent as the OSFED diagnostic criteria	16
Missing links in preeclampsia cell model systems of endothelial dysfunction	16
The future of phage therapy in the USA	16
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	16
Treatment and research needs for severe eating disorders: a response to Dr Ayton	15
Multiomics tools for improved atherosclerotic cardiovascular disease management	15
Dynamic rewiring of neurovasculature in health and disease	15
Strategies to Identify Genetic Variants Causing Infertility	15
Adenoviruses in medicine: innocuous pathogen, predator, or partner	15

IL-6: a pivotal molecule for tumor–brain dysfunction interaction	15
Clinical crusade: zosurabalpin's charge against antibiotic resistance	15
Redefining metalloproteases specificity through network proteolysis	15
Secondary failure: immune responses to approved protein therapeutics	15
The aging lipidome: exercise is medicine	15
Advisory Board and Contents	15
Extracellular matrix-based cancer targeting	15
Rejuvenating the human gut microbiome	14
Nanocarrier vaccines for respiratory infections	14
Helicobacter pylori-induced NF-κB: trailblazer for gastric pathophysiology	14
Enhancers in disease: molecular basis and emerging treatment strategies	14
Subscription and Copyright Information	13
Cancer driver mutations: predictions and reality	13
Advances in Hodgkin lymphoma research	13
Advisory Board and Contents	13
Advisory Board and Contents	13
Safety of non-replicative and oncolytic replication-selective HSV vectors	13
Short-chain fatty acids in fetal development and metabolism	12
Subscription and Copyright Information	12
Are GLP-1R agonists the long-sought-after panacea for obesity?	12
Advisory Board and Contents	12
Subscription and Copyright Information	12
Digital health applications for eating disorders treatment	12
Science around the world	12
Bearing allostatic load: insights into a more equitable future within cardio-oncology	12
Brain-related sexual dimorphism in tuberous sclerosis complex: an overlooked matter	11
Understanding preeclampsia: from phenotypes to treatment	11
Gene therapy for β-thalassemia: current and future options	11
Interdisciplinary approaches for the discovery of novel antifungals	11
Nontraditional models as research tools: the road not taken	11
Epigenetic regulation of tumor-immune symbiosis in glioma	11
Novel bladder-sparing approaches in patients with muscle-invasive bladder cancer	11
Pig models for translational Duchenne muscular dystrophy research	11
Clonal hematopoiesis of indeterminate potential: the root cause of, and fertile ground for, hematological malignancies	11
Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements	11
Toward low-cost gene therapy: mRNA-based therapeutics for treatment of inherited retinal diseases	11
Updates and advances in pyruvate kinase deficiency	11
The multifaceted therapeutic value of targeting ATP-citrate lyase in atherosclerosis	11
Preimplantation Genetic Testing for Aneuploidy – a Castle Built on Sand	11
Subscription and Copyright Information	10
Subscription and Copyright Information	10
Physical activity, cathepsin B, and cognitive health	10
Antibody class-switching as a strategy to improve HIV-1 neutralization	10
Nanobodies as a powerful platform for biomedicine	10
Advisory Board and Contents	10
Genetic causes of obesity: mapping a path forward	10
ILC2s in cancer: good, bad, or stay tuned?	10
Advisory Board and Contents	10
Correction to: siRNA modification and delivery for drug development	10
NK cells in the brain: implications for brain tumor development and therapy	10
Next-generation immune profiling – beyond blood cancer cells	10
Nutrition interventions in congenital disorders of glycosylation	9
Recent insights into lysosomal acid lipase deficiency	9
Patients as biomedical researchers	9
Pulmonary fibrosis: from pathogenesis to clinical decision-making	9
From pathophysiology to treatment in transthyretin cardiac amyloidosis	9
Development of asparagine endopeptidase inhibitors for treating neurodegenerative diseases	9
Subscription and Copyright Information	9
Can’t handle the stress? Mechanobiology and disease	9
The body is not just impacted by eating disorders – biology drives them	9
Advancements and challenges in mouse models of Alzheimer’s disease	9
Exploiting pancreatic cancer metabolism: challenges and opportunities	9
Cell-free and extrachromosomal DNA profiling of small cell lung cancer	9
Delaying Reproductive Aging by Ovarian Tissue Cryopreservation and Transplantation: Is it Prime Time?	9
PIK3CA-related overgrowth: silver bullets from the cancer arsenal?	9
Exposing the role of metals in neurological disorders: a focus on manganese	9
Advisory Board and Contents	8
Science around the world	8
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A sex-biased target against demyelination in Alzheimer’s disease	8
Subscription and Copyright Information	8
Advisory Board and Contents	8
Stories in Molecular Medicine September 2021	8
SARS-CoV-2 targets the liver and manipulates glucose metabolism	8
Pulmonary arterial hypertension and cancer: exploring their resemblance as channelopathies	8
Erythrophagocytes in hemolytic anemia, wound healing, and cancer	8
Convalescent plasma to deliver therapeutic antibodies against COVID-19	8
Technologies for chimeric antigen receptor transgene delivery	8
Post-acute anti-NMDAR encephalitis mirrors schizophrenia	8
Advisory Board and Contents	8
RyR-mediated calcium release in hippocampal health and disease	7
Translating osteoarthritis genetics research: challenging times ahead	7
Psoriatic arthritis: diagnosis, pathogenesis, and emerging therapies	7
Microbiome-targeted interventions for the control of oral–gut dysbiosis and chronic systemic inflammation	7
Powering immunity: mitochondrial dynamics in natural killer cells	7
Suicide prevention in cancer: earlier is better	7
Molecular therapy for polyQ disorders: from bench to clinical trials	7
Burden of hereditary enamel disorders	7
New strategies for the treatment of chronic hepatitis B	6
New insights into gut microbiota–prostate cancer crosstalk	6
Host–microbe interactions in NAD+ metabolism	6
The molecular underpinnings of female predominance in lupus	6
Monoamines' role in islet cell function and type 2 diabetes risk	6
Harnessing the healing power of love	6
Cancer quiescence: non-coding RNAs in the spotlight	6