Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	401
Advisory Board and Contents	251
Subscription and Copyright Information	207
The emerging regulatory interface between DNA repair and steroid hormone receptors in cancer	203
Gene therapies for neurogenetic disorders	182
Endocrinology-informed neuroimaging in eating disorders: GLP1, orexins, and psilocybin	173
PD-L1 at the crossroad between RNA metabolism and immunosuppression	165
Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis	155
Unleashing cell-penetrating peptide applications for immunotherapy	134
Translating osteoarthritis genetics research: challenging times ahead	116
The gut microbiome as a biomarker of differential susceptibility to SARS-CoV-2	106
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	102
Advisory Board and Contents	101
Bringing vascularization into glioblastoma in vitro models	96
Subscription and Copyright Information	94
Advisory Board and Contents	90
Advisory Board and Contents	88
Advisory Board and Contents	84
Advisory Board and Contents	78
Stories in Molecular Medicine April 2021	72
Subscription and Copyright Information	71
Stories in Molecular Medicine December 2021	71
Subscription and Copyright Information	69
Stories in Molecular Medicine September 2021	69
Subscription and Copyright Information	68

Advisory Board and Contents	65
Subscription and Copyright Information	63
Advisory Board and Contents	63
Advisory Board and Contents	60
Advisory Board and Contents	60
Subscription and Copyright Information	59
Subscription and Copyright Information	58
Cutaneous neuroimmune crosstalk in pruritus	54
Organoids, Where We Stand and Where We Go	54
Convalescent plasma to deliver therapeutic antibodies against COVID-19	54
Advisory Board and Contents	51
Vascular dysfunction in Hutchinson–Gilford progeria syndrome	50
Meeting the needs of patients with ultrarare diseases	50
Post-acute anti-NMDAR encephalitis mirrors schizophrenia	50
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	49
Targeting CDK2 to circumvent treatment resistance in HR+ breast cancer	46
Subscription and Copyright Information	45
Microbiome-targeted interventions for the control of oral–gut dysbiosis and chronic systemic inflammation	45
Beyond the danger signal: RNA aggregates orchestrate immunotherapy	42
COVID-19 in pregnancy: implications for fetal brain development	42
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	42
Printing New Bones: From Print-and-Implant Devices to Bioprinted Bone Organ Precursors	42
Unmasking BACE1 in aging and age-related diseases	40
Consideration of the importance of measuring thermal discomfort in biomedical research	39
PROT3EcT, engineered Escherichia coli for the targeted delivery of therapeutics	39
Opportunities and challenges for biomarker discovery using electronic health record data	39
Targeting PERK to treat arrhythmias	39
TIM-3 blockade: immune and targeted therapy in DIPG	38
Neutrophils and extracellular traps in crystal-associated diseases	38
mRNA vaccine platforms to prevent bacterial infections	38
RyR-mediated calcium release in hippocampal health and disease	38
Vitiligo: advances in pathophysiology research and treatment development	38
TIM-3 inhibitors: a promising strategy for tumor immunotherapy	37
Challenges and opportunities for conceiving genetically diverse sickle cell mice	36
Neuroendocrine insights into neurosteroid therapy for postpartum depression	36
Pre-eclampsia: Challenges for Nanomedicine Development in Pregnancy	35
AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies	35
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	35
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	34
Control of DUX4 Expression in Facioscapulohumeral Muscular Dystrophy and Cancer	34
A cryptic mode of GPCR regulation revealed	33
Imaging genomics: data fusion in uncovering disease heritability	32
Science around the world	32
Suicide prevention in cancer: earlier is better	32
Subscription and Copyright Information	32
SARS-CoV-2 targets the liver and manipulates glucose metabolism	32
Breakthroughs and bottlenecks in autophagy research	32
Advisory Board and Contents	32
Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies	31
Advisory Board and Contents	30

m6A and beyond: RNA modifications shaping angiogenesis	30
Vaccine-based immunotherapy and related preclinical models for glioma	29
Understanding the tuberculosis granuloma: the matrix revolutions	28
Molecular therapy for polyQ disorders: from bench to clinical trials	27
Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease	27
Homeostatic maintenance of the lymphatic vasculature	27
Beneath the radar: immune-evasive cell sources for stroke therapy	27
Subscription and Copyright Information	27
AAV capsid design: A Goldilocks challenge	27
A sex-biased target against demyelination in Alzheimer’s disease	26
Particulate matter and Alzheimer’s disease: an intimate connection	26
Fc-optimized checkpoint antibodies for cancer immunotherapy	26
Bridging rapid and sustained antidepressant effects of ketamine	26
Polycystic kidney disease: novel insights into polycystin function	25
Alternative splicing: a bridge connecting NAFLD and HCC	25
Resistance exercise for anxiety and depression: efficacy and plausible mechanisms	24
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	24
Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines	24
The variant landscape and function of DDX3X in cancer and neurodevelopmental disorders	24
The physiology of bilirubin: health and disease equilibrium	24
CXCR2 chemokine receptor – a master regulator in cancer and physiology	24
d-Amino acids: new clinical pathways for brain diseases	23
Pushing the boundaries of brain organoids to study Alzheimer’s disease	23
Asthma exacerbations: the Achilles heel of asthma care	23
Hidden mysteries behind genome, epigenome, and exposome of lupus erythematosus	22
Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges	22
Circular RNA translation: novel protein isoforms and clinical significance	22
HPV integration and cervical cancer: a failed evolutionary viral trait	22
Microbiota and sleep: awakening the gut feeling	22
Autoimmune diseases and cardiovascular risk	22
Dietary interventions and precision nutrition in cancer therapy	22
Tackling ‘lost in translation’ issues: a response to Perez-Campos et al.	21
Staging of Alzheimer’s disease: past, present, and future perspectives	21
New strategies for the treatment of chronic hepatitis B	21
Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation	21
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Targeting low-risk myelodysplastic syndrome with novel therapeutic strategies	21
Subscription and Copyright Information	20
Subscription and Copyright Information	20
Three ‘E’ challenges for siRNA drug development	20
Turning the tide in aggressive lymphoma: liquid biopsy for risk-adapted treatment strategies	20
Advisory Board and Contents	20
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	19
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects	19
Subscription and Copyright Information	19
Engineering cytokines for tumor-targeting and selective T cell activation	19
Emerging roles of cyclin-dependent kinase 7 in health and diseases	19
Beyond memory impairment: the complex phenotypic landscape of Alzheimer’s disease	18
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	18
Strategies to Identify Genetic Variants Causing Infertility	18
Dysregulation of deubiquitinylases: a linchpin of gastrointestinal diseases	18
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Missing links in preeclampsia cell model systems of endothelial dysfunction	17
Role and therapeutic implications of protein glycosylation in neuroinflammation	17
Can we provide quality #MedEd on social media?	17
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	17
Advisory Board and Contents	17
Tertiary lymphoid structures in the central nervous system	17
CircRNA perspective: new strategies for RNA therapy	17
How hypocretin agonists may improve the quality of wake in narcolepsy	16
Stories in Molecular Medicine November 2021	16
Brain-specific regulatory T cell expansion limits cognitive decline	16
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	16
β2ARs: double edge sword in heart function	16
Stories in Molecular Medicine October 2021	16
Advisory Board and Contents	16
A Rare Kidney Disease To Cure Them All? Towards Mechanism-Based Therapies for Proteinopathies	16
Fibrodysplasia ossificans progressiva emerges from obscurity	15
Deep learning for subtyping the Alzheimer’s disease spectrum	15
The inaccessible road to science for people with disabilities	15
Microbes and mood: innovative biomarker approaches in depression	15
Subscription and Copyright Information	15
Copy number alterations: a catastrophic orchestration of the breast cancer genome	15
In Utero Gene Therapy: Progress and Challenges	14
Post-Transcriptional Regulation in Skeletal Muscle Development, Repair, and Disease	14
Improving participant representation in the era of digital clinical studies	14
Advisory Board and Contents	14
If it ain’t broke, break it: facilitating antigen cross-presentation	14
Data-Driven Modeling of Pregnancy-Related Complications	14
Monoamines' role in islet cell function and type 2 diabetes risk	14

Organ-specific aging in the plasma proteome predicts disease	13
Harnessing the healing power of love	13
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	13
Science around the world	13
Insights from HIV-1 vaccine and passive immunization efficacy trials	13
Breakthroughs and Bottlenecks in Microbiome Research	13
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	13
Targeting monoamine oxidases in cancer: advances and opportunities	13
Circadian phase instability in bipolar disorder: a neglected essence	13
Engineering Strategies for Allogeneic Solid Tissue Acceptance	13
Hormesis as an adaptive response to infection	13
Oligodendrocyte pathology in Huntington’s disease: from mechanisms to therapeutics	13
Science around the world	13
Anorexia nervosa: diagnostic, therapeutic, and risk biomarkers in clinical practice	12
Molecular mechanisms in the pathogenesis of dengue infections	12
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	12
The dual role of the TSC complex in cancer	12
iPSCs and DRGs: stepping stones to new pain therapies	12
Erythropoietic protoporphyrias: updates and advances	12
Amyloid and collagen templates in aortic valve calcification	12
Cell-free circulating tumor DNA profiling in cancer management	12
Advisory Board and Contents	12
There is nothing as inconsistent as the OSFED diagnostic criteria	12
COVID-19 vaccines in pregnancy	11
IBD disease-modifying therapies: insights from emerging therapeutics	11
FSP1: a key regulator of ferroptosis	11
Extracellular matrix-based cancer targeting	11
Moyamoya disease emerging as an immune-related angiopathy	11
Communicating science and protecting scientists in a time of political instability	11
Senescence and tissue fibrosis: opportunities for therapeutic targeting	11
The molecular underpinnings of female predominance in lupus	11
Unlocking the potential of agonist antibodies for treating cancer using antibody engineering	11
Thymic stroma and TFII-I: towards new targeted therapies	11
N6-methyladenosine-mediated gene regulation and therapeutic implications	11
Epigenetic regulation in intervertebral disc degeneration	10
Cancer quiescence: non-coding RNAs in the spotlight	10
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	10
Epigenetic priming in neurodevelopmental disorders	10
Redefining metalloproteases specificity through network proteolysis	10
Primary cilia shape hallmarks of health and aging	10
Telomere biology disorders: time for moving towards the clinic?	10
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	9
The kynurenine pathway in chronic diseases: a compensatory mechanism or a driving force?	9
Eating disorders and obesity: bridging clinical, neurobiological, and therapeutic perspectives	9
Molecular links between allergy and cancer	9
Common mechanisms in pediatric acute liver failure	9
Ectodysplasin A2 receptor signaling in skeletal muscle pathophysiology	9
Host-informed therapies for the treatment of pneumococcal pneumonia	9
Readthrough compounds for nonsense mutations: bridging the translational gap	8
Amphiphysin-2 (BIN1) functions and defects in cardiac and skeletal muscle	8
Crosstalk between bile acid-activated receptors and microbiome in entero-hepatic inflammation	8
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	8
Molecular pathology of rare progeroid diseases	8
Targeting ACC for NASH resolution	8
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	8
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	8
Leveraging insights from cancer to improve tuberculosis therapy	8
The NRF2/Keap1 pathway as a therapeutic target in inflammatory bowel disease	8
The gut vascular barrier: a new player in the gut–liver–brain axis	8
Advisory Board and Contents	8
Helicobacter pylori-induced NF-κB: trailblazer for gastric pathophysiology	7
Genetically modified malaria parasites as vaccine candidates	7
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Advisory Board and Contents	7
Fruitful Futures for Reproductive Health	7
Primary B cell engineering for therapeutic research	7
Clinical implications of vitamin B12 as redox-active cofactor	7
Shining a light on comorbidities	7
Responding to the ripple effects of sexual harassment: an emergency management framework	7
Advisory Board and Contents	7
Fatty acid binding proteins in multiple myeloma	7
Is there a place for engineered immune cell therapies in autoimmune diseases?	7
TBCK syndrome: a rare multi-organ neurodegenerative disease	7
Advisory Board and Contents	7
Subscription and Copyright Information	7
Advisory Board and Contents	7
Advisory Board and Contents	7
Galectin-3 in metabolic disorders: mechanisms and therapeutic potential	6
3-O-acylated bile acids: disrupters or harmonizers of metabolism?	6
Clinical Potential of Kisspeptin in Reproductive Health	6
Cells of the tumor microenvironment speak the Wnt language	6
Upper respiratory tract mucosal immunity for SARS-CoV-2 vaccines	6
LDL-C augments whereas HDL-C prevents inflammatory innate immune memory	6
SOX17: escape route from immune destruction in early CRC	6
Multiomics tools for improved atherosclerotic cardiovascular disease management	6
InFUSing antisense oligonucleotides for treating ALS	6
Compartmentalization and regulation of GTP in control of cellular phenotypes	6
Secondary failure: immune responses to approved protein therapeutics	6
Dynamic rewiring of neurovasculature in health and disease	6
Bringing gene therapy to where it’s needed	6
Beyond pluripotency: Yamanaka factors drive brain growth and regeneration	6
Interrogating the promise of long-acting HIV pre-exposure prophylaxis	6
Topical Microbial Therapeutics against Respiratory Viral Infections	6
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	6
Advisory Board and Contents	6