Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	233
Subscription and Copyright Information	219
Advisory Board and Contents	203
Subscription and Copyright Information	170
Consideration of the importance of measuring thermal discomfort in biomedical research	166
Advisory Board and Contents	166
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	147
Fc-optimized checkpoint antibodies for cancer immunotherapy	133
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	121
Opportunities and challenges for biomarker discovery using electronic health record data	116
Subscription and Copyright Information	108
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	106
Subscription and Copyright Information	101
Subscription and Copyright Information	99
Beneath the radar: immune-evasive cell sources for stroke therapy	97
Advisory Board and Contents	93
Stories in Molecular Medicine December 2021	89
Neutrophils and extracellular traps in crystal-associated diseases	83
Pushing the boundaries of brain organoids to study Alzheimer’s disease	80
m6A and beyond: RNA modifications shaping angiogenesis	79
Microbiota: a dawn for cancer metastasis therapy	74
d-Amino acids: new clinical pathways for brain diseases	72
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	72
Microbes and mood: innovative biomarker approaches in depression	70
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	70

Insights from HIV-1 vaccine and passive immunization efficacy trials	67
Advisory Board and Contents	66
Emerging roles of cyclin-dependent kinase 7 in health and diseases	64
Amyloid and collagen templates in aortic valve calcification	64
Brain-specific regulatory T cell expansion limits cognitive decline	63
Subscription and Copyright Information	62
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	56
Epigenetic regulation in intervertebral disc degeneration	55
Stories in Molecular Medicine November 2021	53
Erythropoietic protoporphyrias: updates and advances	52
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	52
Engineering cytokines for tumor-targeting and selective T cell activation	52
Three ‘E’ challenges for siRNA drug development	51
iPSCs and DRGs: stepping stones to new pain therapies	48
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	48
RNA immunotherapy: revolutionizing cancer and autoimmune disease treatments	47
Keratinocytes: new perspectives in inflammatory skin diseases	46
Acquired resistance to immunotherapy in solid tumors	46
Promoting proteostasis by cAMP/PKA and cGMP/PKG	45
Hormesis as an adaptive response to infection	45
Skeletal muscle mitochondrial network dynamics in metabolic disorders and aging	45
Molecular mechanisms in the pathogenesis of dengue infections	45
Significant challenges to translating breakthrough science in Mexico	44
Pathogenic mechanisms in genetically defined Ehlers–Danlos syndromes	43
Mitigating age-related somatic mutation burden	43
The endoplasmic reticulum proteostasis network and bone disease	42
SOX17: escape route from immune destruction in early CRC	41
Subscription and Copyright Information	41
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	41
Advisory Board and Contents	40
Shining a light on comorbidities	40
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation	40
Subscription and Copyright Information	40
Roadmap for developing biologically inspired therapeutics for genetic brain disorders	39
Advisory Board and Contents	39
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	39
CircRNA perspective: new strategies for RNA therapy	38
Antibody signatures in inflammatory bowel disease: current developments and future applications	38
The bleeding edge: broadening horizons for hematopoietic stem cell therapies	37
Timing matters: maternal milk IgG sets weaning threshold	36
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	36
Naked mole-rats: at the heart of it	36
Two-pronged immune evasion of pseudouridine-modified RNA	35
Targeting mitochondrial transfer as a promising therapeutic strategy	34
Molecular disease mechanisms of human antineuronal monoclonal autoantibodies	34
Saving eyesight, one gene at a time	34
Subscription and Copyright Information	33
Time-restricted feeding and Alzheimer’s disease: you are when you eat	32
Science around the world	32
Translation of gene therapy strategies for amyotrophic lateral sclerosis	31

The emerging Janus face of SVEP1 in development and disease	31
Focused ultrasound gene delivery for the treatment of neurological disorders	31
Intestinal mucus barrier: a missing piece of the puzzle in food allergy	30
Maternal obesity: new placental paradigms unfolded	29
IL-15 in CAR engineering: striking an efficacy–safety balance	29
Cystic fibrosis at a glance: from disease mechanism to therapy	28
Science around the world	28
Incorporating placental pathology into clinical care and research	28
Skin senescence: mechanisms and impact on whole-body aging	28
Advisory Board and Contents	28
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes	27
Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach	27
Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery	27
Gasdermins in pyroptosis, inflammation, and cancer	27
ABC transporters: human disease and pharmacotherapeutic potential	27
Splicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer	26
Advisory Board and Contents	26
Fibroblasts in AKI: small army, big help	26
Biodiversity: the overlooked source of human health	25
Leveraging cellular mechano-responsiveness for cancer therapy	25
Autoantibodies as drivers of neuropathic pain	25
Advisory Board and Contents	25
Translational opportunities emerge from genetic influences on health	25
Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health	25
Subscription and Copyright Information	24
Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes	24
Clock-modulated checkpoints in time-restricted eating	24
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	24
The global human gut microbiome: genes, lifestyles, and diet	24
Advisory Board and Contents	23
Novel universal vaccines to mitigate emerging avian influenza viruses	23
Molecular basis and clinical implications of HIFs in cardiovascular diseases	23
iPSC-derived models for anorexia nervosa research	23
Human dopaminergic system in the exercise-cognition link	22
BH3 mimetic therapies for CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia	22
Stratum corneum as polymer sheet: concept and cornification processes	21
Advisory Board and Contents	20
Vaccine-based immunotherapy and related preclinical models for glioma	20
Subscription and Copyright Information	20
Subscription and Copyright Information	20
Circadian molecular clock disruption in chronic pulmonary diseases	20
Dissecting mechanisms of fecal microbiota transplantation efficacy in disease	20
mRNA vaccine platforms to prevent bacterial infections	19
Autoimmune diseases and cardiovascular risk	19
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	19
Advisory Board and Contents	19
Deciphering the MYCN-driven metabolic microenvironment of neuroblastoma	19
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	19
Asthma exacerbations: the Achilles heel of asthma care	19
HPV integration and cervical cancer: a failed evolutionary viral trait	19
Subscription and Copyright Information	19
Understanding the tuberculosis granuloma: the matrix revolutions	19
TIM-3 blockade: immune and targeted therapy in DIPG	19
AAV capsid design: A Goldilocks challenge	18
Vitiligo: advances in pathophysiology research and treatment development	18
Staging of Alzheimer’s disease: past, present, and future perspectives	18
Advisory Board and Contents	18
Renin–angiotensin system: a novel target for brain health	18
The dual role of the TSC complex in cancer	17
The future of phage therapy in the USA	17
Tertiary lymphoid structures in the central nervous system	17
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	17
Organ-specific aging in the plasma proteome predicts disease	17
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	17
Copy number alterations: a catastrophic orchestration of the breast cancer genome	16
Telomere biology disorders: time for moving towards the clinic?	16
Missing links in preeclampsia cell model systems of endothelial dysfunction	16
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	16
Trained immunity-related vaccines: innate immune memory and heterologous protection against infections	16
Thymic stroma and TFII-I: towards new targeted therapies	16
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	16
Redefining metalloproteases specificity through network proteolysis	16
There is nothing as inconsistent as the OSFED diagnostic criteria	16
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	16
Common mechanisms in pediatric acute liver failure	16
Clinical crusade: zosurabalpin's charge against antibiotic resistance	15
Primary cilia shape hallmarks of health and aging	15
Advisory Board and Contents	15
Multiomics tools for improved atherosclerotic cardiovascular disease management	15
Rejuvenating the human gut microbiome	15

Nanocarrier vaccines for respiratory infections	15
The aging lipidome: exercise is medicine	15
Treatment and research needs for severe eating disorders: a response to Dr Ayton	15
IL-6: a pivotal molecule for tumor–brain dysfunction interaction	15
Helicobacter pylori-induced NF-κB: trailblazer for gastric pathophysiology	15