Trends in Molecular Medicine

Article	Citations
Advisory Board and Contents	246
Subscription and Copyright Information	239
Advisory Board and Contents	211
Subscription and Copyright Information	188
Advisory Board and Contents	180
Microbiota: a dawn for cancer metastasis therapy	168
Consideration of the importance of measuring thermal discomfort in biomedical research	148
The right drug at the right time: key to IBD success	133
Fc-optimized checkpoint antibodies for cancer immunotherapy	121
Subscription and Copyright Information	117
Subscription and Copyright Information	115
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	112
Subscription and Copyright Information	107
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	105
Neutrophils and extracellular traps in crystal-associated diseases	99
Opportunities and challenges for biomarker discovery using electronic health record data	97
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	89
Lymph node microenvironment rewires ferroptosis redox defenses	88
Beneath the radar: immune-evasive cell sources for stroke therapy	81
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	80
m6A and beyond: RNA modifications shaping angiogenesis	78
Pushing the boundaries of brain organoids to study Alzheimer’s disease	77
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	76
d-Amino acids: new clinical pathways for brain diseases	76
Microbes and mood: innovative biomarker approaches in depression	75

Advisory Board and Contents	72
Subscription and Copyright Information	70
Brain-specific regulatory T cell expansion limits cognitive decline	70
Systemically administered alcadein peptide p3-Alcβ neutralizes brain Alzheimer’s Aβ oligomers	69
iPSCs and DRGs: stepping stones to new pain therapies	69
Insights from HIV-1 vaccine and passive immunization efficacy trials	67
HDAC inhibitors as pharmacological treatment for Duchenne muscular dystrophy: a discovery journey from bench to patients	63
Molecular mechanisms in the pathogenesis of dengue infections	62
Amyloid and collagen templates in aortic valve calcification	61
Hormesis as an adaptive response to infection	57
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	56
Keratinocytes: new perspectives in inflammatory skin diseases	56
Acquired resistance to immunotherapy in solid tumors	53
RNA immunotherapy: revolutionizing cancer and autoimmune disease treatments	51
Epigenetic regulation in intervertebral disc degeneration	51
Emerging roles of cyclin-dependent kinase 7 in health and diseases	50
Erythropoietic protoporphyrias: updates and advances	50
Three ‘E’ challenges for siRNA drug development	49
Significant challenges to translating breakthrough science in Mexico	49
Engineering cytokines for tumor-targeting and selective T cell activation	49
The endoplasmic reticulum proteostasis network and bone disease	48
Antibody signatures in inflammatory bowel disease: current developments and future applications	46
Subscription and Copyright Information	45
Mitigating age-related somatic mutation burden	45
SOX17: escape route from immune destruction in early CRC	45
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Roadmap for developing biologically inspired therapeutics for genetic brain disorders	44
Advisory Board and Contents	44
Advisory Board and Contents	43
Shining a light on comorbidities	43
Promoting proteostasis by cAMP/PKA and cGMP/PKG	42
Subscription and Copyright Information	42
Leptin and male fertility: unraveling the molecular pathways, receptor functions, and therapeutic potential	42
Strategies and challenges for non-viral delivery of non-coding RNAs to the heart	42
Pathogenic mechanisms in genetically defined Ehlers–Danlos syndromes	41
The bleeding edge: broadening horizons for hematopoietic stem cell therapies	39
CircRNA perspective: new strategies for RNA therapy	39
Immune cell-derived signals governing epithelial phenotypes in homeostasis and inflammation	39
Naked mole-rats: at the heart of it	37
Translation of gene therapy strategies for amyotrophic lateral sclerosis	36
Timing matters: maternal milk IgG sets weaning threshold	35
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	35
Two-pronged immune evasion of pseudouridine-modified RNA	35
Science around the world	34
Molecular disease mechanisms of human antineuronal monoclonal autoantibodies	34
Saving eyesight, one gene at a time	34
Time-restricted feeding and Alzheimer’s disease: you are when you eat	34
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Intestinal mucus barrier: a missing piece of the puzzle in food allergy	33
Focused ultrasound gene delivery for the treatment of neurological disorders	32

Targeting mitochondrial transfer as a promising therapeutic strategy	31
IL-15 in CAR engineering: striking an efficacy–safety balance	31
Skin senescence: mechanisms and impact on whole-body aging	31
The emerging Janus face of SVEP1 in development and disease	30
Maternal obesity: new placental paradigms unfolded	30
Science around the world	29
Autoantibodies as drivers of neuropathic pain	29
Advisory Board and Contents	29
Unraveling host genetics and microbiome genome crosstalk: a novel therapeutic approach	29
Translational opportunities emerge from genetic influences on health	28
Advisory Board and Contents	28
Advisory Board and Contents	28
Cystic fibrosis at a glance: from disease mechanism to therapy	28
Crucial nuances in understanding (mis)associations between the neonatal microbiome and Cesarean delivery	27
Lipedema: a chronic adipose tissue disease	27
Leveraging zebrafish to investigate pancreatic development, regeneration, and diabetes	27
Clock-modulated checkpoints in time-restricted eating	27
Fibroblasts in AKI: small army, big help	27
The overlooked uterine factor: unlocking endometrium potential in premature ovarian insufficiency	26
Incorporating placental pathology into clinical care and research	25
Gasdermins in pyroptosis, inflammation, and cancer	25
ABC transporters: human disease and pharmacotherapeutic potential	25
Splicing dysregulation: hallmark and therapeutic opportunity in pancreatic cancer	25
The global human gut microbiome: genes, lifestyles, and diet	24
Olfactory dysfunction in COVID-19: pathology and long-term implications for brain health	24
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Leveraging cellular mechano-responsiveness for cancer therapy	24
Therapeutic potential of PANoptosis: innate sensors, inflammasomes, and RIPKs in PANoptosomes	24
Biodiversity: the overlooked source of human health	24
iPSC-derived models for anorexia nervosa research	23
Advisory Board and Contents	23
Novel universal vaccines to mitigate emerging avian influenza viruses	23
BH3 mimetic therapies for CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia	23
From pixels to patients: the evolution and future of deep learning in cancer diagnostics	23
Subscription and Copyright Information	22
Advisory Board and Contents	22
Stratum corneum as polymer sheet: concept and cornification processes	22
Molecular basis and clinical implications of HIFs in cardiovascular diseases	21
Vaccine-based immunotherapy and related preclinical models for glioma	21
Human dopaminergic system in the exercise-cognition link	21
Dissecting mechanisms of fecal microbiota transplantation efficacy in disease	21
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Circadian molecular clock disruption in chronic pulmonary diseases	21
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	21
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	20
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Autoimmune diseases and cardiovascular risk	20
Advisory Board and Contents	20
Renin–angiotensin system: a novel target for brain health	20
AAV capsid design: A Goldilocks challenge	20
TIM-3 blockade: immune and targeted therapy in DIPG	20
Deciphering the MYCN-driven metabolic microenvironment of neuroblastoma	20
Vitiligo: advances in pathophysiology research and treatment development	19
Advisory Board and Contents	19
HPV integration and cervical cancer: a failed evolutionary viral trait	19
Understanding the tuberculosis granuloma: the matrix revolutions	19
mRNA vaccine platforms to prevent bacterial infections	19
Staging of Alzheimer’s disease: past, present, and future perspectives	19
Asthma exacerbations: the Achilles heel of asthma care	19
Organ-specific aging in the plasma proteome predicts disease	19
Treating Niemann-Pick C lysosomal storage: approved and emerging approaches	18
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	18
Telomere biology disorders: time for moving towards the clinic?	17
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	17
Repurposing of microbial proteins as new-generation therapeutic agents for biomedical applications	17
Common mechanisms in pediatric acute liver failure	17
Bioelectronic medicine potentiates endogenous NSCs for neurodegenerative diseases	17
Dysfunctional tRNA reprogramming and codon-biased translation in cancer	17
Thymic stroma and TFII-I: towards new targeted therapies	17
Predicting healthspan and disease risks through biological age	17
There is nothing as inconsistent as the OSFED diagnostic criteria	17
Missing links in preeclampsia cell model systems of endothelial dysfunction	16
Primary cilia shape hallmarks of health and aging	16
Copy number alterations: a catastrophic orchestration of the breast cancer genome	16
The dual role of the TSC complex in cancer	16
Treatment and research needs for severe eating disorders: a response to Dr Ayton	16
Clinical crusade: zosurabalpin's charge against antibiotic resistance	16
Tertiary lymphoid structures in the central nervous system	16
Redefining metalloproteases specificity through network proteolysis	16
The future of phage therapy in the USA	16

Trained immunity-related vaccines: innate immune memory and heterologous protection against infections

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