OOIR: Observatory of International Research

Papers

(The TQCC of Trends in Molecular Medicine is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Advisory Board and Contents	401
Advisory Board and Contents	251
Subscription and Copyright Information	207
The emerging regulatory interface between DNA repair and steroid hormone receptors in cancer	203
Gene therapies for neurogenetic disorders	182
Endocrinology-informed neuroimaging in eating disorders: GLP1, orexins, and psilocybin	173
PD-L1 at the crossroad between RNA metabolism and immunosuppression	165
Considerations for capsid-targeting antiretrovirals in pre-exposure prophylaxis	155
Unleashing cell-penetrating peptide applications for immunotherapy	134
Translating osteoarthritis genetics research: challenging times ahead	116
The gut microbiome as a biomarker of differential susceptibility to SARS-CoV-2	106
Preventing unfolded protein response-induced ion channel dysregulation to treat arrhythmias	102
Advisory Board and Contents	101
Bringing vascularization into glioblastoma in vitro models	96
Subscription and Copyright Information	94
Advisory Board and Contents	90
Advisory Board and Contents	88
Advisory Board and Contents	84
Advisory Board and Contents	78
Stories in Molecular Medicine April 2021	72
Stories in Molecular Medicine December 2021	71
Subscription and Copyright Information	71
Subscription and Copyright Information	69
Stories in Molecular Medicine September 2021	69
Subscription and Copyright Information	68

Advisory Board and Contents	65
Advisory Board and Contents	63
Subscription and Copyright Information	63
Advisory Board and Contents	60
Advisory Board and Contents	60
Subscription and Copyright Information	59
Subscription and Copyright Information	58
Convalescent plasma to deliver therapeutic antibodies against COVID-19	54
Cutaneous neuroimmune crosstalk in pruritus	54
Organoids, Where We Stand and Where We Go	54
Advisory Board and Contents	51
Post-acute anti-NMDAR encephalitis mirrors schizophrenia	50
Vascular dysfunction in Hutchinson–Gilford progeria syndrome	50
Meeting the needs of patients with ultrarare diseases	50
Bursts of brain erosion: seizures and age-dependent neurological vulnerability	49
Targeting CDK2 to circumvent treatment resistance in HR+ breast cancer	46
Microbiome-targeted interventions for the control of oral–gut dysbiosis and chronic systemic inflammation	45
Subscription and Copyright Information	45
Beyond the danger signal: RNA aggregates orchestrate immunotherapy	42
COVID-19 in pregnancy: implications for fetal brain development	42
Glycosylation of blood cells during the onset and progression of atherosclerosis and myocardial infarction	42
Printing New Bones: From Print-and-Implant Devices to Bioprinted Bone Organ Precursors	42
Unmasking BACE1 in aging and age-related diseases	40
Consideration of the importance of measuring thermal discomfort in biomedical research	39
PROT3EcT, engineered Escherichia coli for the targeted delivery of therapeutics	39
Opportunities and challenges for biomarker discovery using electronic health record data	39
Targeting PERK to treat arrhythmias	39
RyR-mediated calcium release in hippocampal health and disease	38
Vitiligo: advances in pathophysiology research and treatment development	38
TIM-3 blockade: immune and targeted therapy in DIPG	38
Neutrophils and extracellular traps in crystal-associated diseases	38
mRNA vaccine platforms to prevent bacterial infections	38
TIM-3 inhibitors: a promising strategy for tumor immunotherapy	37
Neuroendocrine insights into neurosteroid therapy for postpartum depression	36
Challenges and opportunities for conceiving genetically diverse sickle cell mice	36
Cellular senescence in neuroinflammatory disease: new therapies for old cells?	35
Pre-eclampsia: Challenges for Nanomedicine Development in Pregnancy	35
AAV-Mediated Gene Therapy for Glycosphingolipid Biosynthesis Deficiencies	35
Medical imaging of pulmonary disease in SARS-CoV-2-exposed non-human primates	34
Control of DUX4 Expression in Facioscapulohumeral Muscular Dystrophy and Cancer	34
A cryptic mode of GPCR regulation revealed	33
Breakthroughs and bottlenecks in autophagy research	32
Advisory Board and Contents	32
Imaging genomics: data fusion in uncovering disease heritability	32
Science around the world	32
Suicide prevention in cancer: earlier is better	32
Subscription and Copyright Information	32
SARS-CoV-2 targets the liver and manipulates glucose metabolism	32
Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies	31
m6A and beyond: RNA modifications shaping angiogenesis	30

Advisory Board and Contents	30
Vaccine-based immunotherapy and related preclinical models for glioma	29
Understanding the tuberculosis granuloma: the matrix revolutions	28
Molecular therapy for polyQ disorders: from bench to clinical trials	27
Ancestry, ethnicity, and race: explaining inequalities in cardiometabolic disease	27
Homeostatic maintenance of the lymphatic vasculature	27
Beneath the radar: immune-evasive cell sources for stroke therapy	27
Subscription and Copyright Information	27
AAV capsid design: A Goldilocks challenge	27
Bridging rapid and sustained antidepressant effects of ketamine	26
A sex-biased target against demyelination in Alzheimer’s disease	26
Particulate matter and Alzheimer’s disease: an intimate connection	26
Fc-optimized checkpoint antibodies for cancer immunotherapy	26
Alternative splicing: a bridge connecting NAFLD and HCC	25
Polycystic kidney disease: novel insights into polycystin function	25
Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines	24
The variant landscape and function of DDX3X in cancer and neurodevelopmental disorders	24
The physiology of bilirubin: health and disease equilibrium	24
CXCR2 chemokine receptor – a master regulator in cancer and physiology	24
Resistance exercise for anxiety and depression: efficacy and plausible mechanisms	24
Hyperemesis gravidarum theories dispelled by recent research: a paradigm change for better care and outcomes	24
Pushing the boundaries of brain organoids to study Alzheimer’s disease	23
Asthma exacerbations: the Achilles heel of asthma care	23
d-Amino acids: new clinical pathways for brain diseases	23
HPV integration and cervical cancer: a failed evolutionary viral trait	22
Microbiota and sleep: awakening the gut feeling	22
Autoimmune diseases and cardiovascular risk	22
Dietary interventions and precision nutrition in cancer therapy	22
Hidden mysteries behind genome, epigenome, and exposome of lupus erythematosus	22
Strategies of pluripotent stem cell-based therapy for retinal degeneration: update and challenges	22
Circular RNA translation: novel protein isoforms and clinical significance	22
Subscription and Copyright Information	21
Targeting low-risk myelodysplastic syndrome with novel therapeutic strategies	21
Tackling ‘lost in translation’ issues: a response to Perez-Campos et al.	21
Staging of Alzheimer’s disease: past, present, and future perspectives	21
New strategies for the treatment of chronic hepatitis B	21
Alternative Polyadenylation in Stem Cell Self-Renewal and Differentiation	21
Turning the tide in aggressive lymphoma: liquid biopsy for risk-adapted treatment strategies	20
Advisory Board and Contents	20
Subscription and Copyright Information	20
Subscription and Copyright Information	20
Three ‘E’ challenges for siRNA drug development	20
Engineering cytokines for tumor-targeting and selective T cell activation	19
Emerging roles of cyclin-dependent kinase 7 in health and diseases	19
Thirty years of molecular medicine: reflections from an academic physician-scientist, 1995–2025	19
Probiotics in inflammatory bowel disease: microbial modulation and therapeutic prospects	19
Subscription and Copyright Information	19
Strategies to Identify Genetic Variants Causing Infertility	18
Dysregulation of deubiquitinylases: a linchpin of gastrointestinal diseases	18
Subscr+copyr	18
Beyond memory impairment: the complex phenotypic landscape of Alzheimer’s disease	18
Advancements in intensive eating disorder treatments: the benefit of CBT-E and integrated care models	18
Can we provide quality #MedEd on social media?	17
Why we must fight ignorance about COVID-19 vaccines and menstrual cycles	17
Advisory Board and Contents	17
Tertiary lymphoid structures in the central nervous system	17
CircRNA perspective: new strategies for RNA therapy	17
Missing links in preeclampsia cell model systems of endothelial dysfunction	17
Role and therapeutic implications of protein glycosylation in neuroinflammation	17
Stories in Molecular Medicine October 2021	16
Advisory Board and Contents	16
A Rare Kidney Disease To Cure Them All? Towards Mechanism-Based Therapies for Proteinopathies	16
How hypocretin agonists may improve the quality of wake in narcolepsy	16
Stories in Molecular Medicine November 2021	16
Brain-specific regulatory T cell expansion limits cognitive decline	16
Manipulating the gut and tumor microbiota for immune checkpoint inhibitor therapy: from dream to reality	16
β2ARs: double edge sword in heart function	16
Subscription and Copyright Information	15
Copy number alterations: a catastrophic orchestration of the breast cancer genome	15
Fibrodysplasia ossificans progressiva emerges from obscurity	15
Deep learning for subtyping the Alzheimer’s disease spectrum	15
The inaccessible road to science for people with disabilities	15
Microbes and mood: innovative biomarker approaches in depression	15
Advisory Board and Contents	14
If it ain’t broke, break it: facilitating antigen cross-presentation	14
Data-Driven Modeling of Pregnancy-Related Complications	14
Monoamines' role in islet cell function and type 2 diabetes risk	14
In Utero Gene Therapy: Progress and Challenges	14
Post-Transcriptional Regulation in Skeletal Muscle Development, Repair, and Disease	14
Improving participant representation in the era of digital clinical studies	14