BMC Biotechnology

Article	Citations
Efficient removal of Congo Red Dye using a MgAl-LDH/cuttlebone composite adsorbent	61
Parabacteroides distasonis promotes CXCL9 secretion of tumor-associated macrophages and enhances CD8+T cell activity to trigger anti-tumor immunity against anti-PD-1 treatment in non-small cell lung c	52
Simplified cloning and isolation of peptides from “sandwiched” SUMO-peptide-intein fusion proteins	45
Identification of a novel fully human anti-toxic shock syndrome toxin (TSST)-1 single-chain variable fragment antibody averting TSST-1-induced mitogenesis and cytokine secretion	45
Improvement and prediction of the extraction parameters of lupeol and stigmasterol metabolites of Melia azedarach with response surface methodology	36
A novel single-vector featuring bidirectional promoters for production of bispecific antibody against rabies virus	34
3D printing of Ceffe-infused scaffolds for tailored nipple-like cartilage development	32
Optimized zymogram protocol from 3D spheroid cultures to study MMP-2 and -9 activities in tumor cells	32
Biocompatibility and potential anticancer activity of gadolinium oxide (Gd2O3) nanoparticles against nasal squamous cell carcinoma	31
The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa	29
N-terminal truncation of the foot-and-mouth disease virus VP0 protein promotes soluble co-expression and particle assembly stability of viral capsid proteins in Escherichia coli	27
Maximizing lipid accumulation in Tetradesmus obliquus under heavy metal stress for sustainable biodiesel innovation	25
Biosafety and pharmacokinetic characteristics of polyethylene pyrrolidone modified nano selenium in rats	22
Enzymatic degradation is an effective means to reduce aflatoxin contamination in maize	22
Fusarium verticillioides pigment: production, response surface optimization, gamma irradiation and encapsulation studies	21
Gellan gum/gelatin Schiff-base hydrogel for ocular drug delivery of timolol maleate	21
Comparison of vector elements and process conditions in transient and stable suspension HEK293 platforms using SARS-CoV-2 receptor binding domain as a model protein	21
Synergistic effect of zinc oxide-cinnamic acid nanoparticles for wound healing management: in vitro and zebrafish model studies	21
Highly multiplexed targeted sequencing strategy for infectious disease surveillance	19
Fabrication and characterization of metformin-loaded PLGA/Collagen nanofibers for modulation of macrophage polarization for tissue engineering and regenerative medicine	19
Transgenic Arabidopsis thaliana plants expressing bacterial γ-hexachlorocyclohexane dehydrochlorinase LinA	19
Optimization of lipase production using fungal isolates from oily residues	18
Evaluating the anticancer efficacy of Chara vulgaris ethanolic extract and selenium nanoformulation in Ehrlich carcinoma mice: role of autophagy and apoptosis	18
Rice yellow mottle virus is a suitable amplicon vector for an efficient production of an anti-leishmianiasis vaccine in Nicotiana benthamiana leaves	18
Electrospun PCL membranes for localized drug delivery and bone regeneration	18

The ESRP1 promoter reporter can function as an in vivo sensor of DNA methyltransferase inhibition	17
A new mRNA structure prediction based approach to identifying improved signal peptides for bone morphogenetic protein 2	17
Generation of a recombinant antibody for sensitive detection of Pseudomonas aeruginosa	16
Biochemical characterization and insights into the potency of the acidic Aspergillus niger NRC114 purified α-galactosidase in removing raffinose family oligosaccharides from soymilk yogurt	15
Purification and characterization of soluble recombinant Crimean-Congo hemorrhagic fever virus glycoprotein Gc expressed in mammalian 293F cells	15
One-step fermentation for producing xylo-oligosaccharides from wheat bran by recombinant Escherichia coli containing an alkaline xylanase	14
Anti-inflammatory potential of aspergillus unguis SP51-EGY: TLR4-dependent effects & chemical diversity via Q-TOF LC-HRMS	14
Soft sensor modeling method for Pichia pastoris fermentation process based on substructure domain transfer learning	14
Chitosan nano-formulation enhances stability and bactericidal activity of the lytic phage HK6	14
Newly designed curcumin-loaded hybrid nanoparticles: a multifunctional strategy for combating oxidative stress, inflammation, and infections to accelerate wound healing and tissue regeneration	14
A critical role for erythropoietin on vagus nerve Schwann cells in intestinal motility	13
Molecular and agro-morphological characterization of new barley genotypes in arid environments	13
Central position of histidine in the sequence of designed alternating polarity peptides enhances pH-responsive assembly with DNA	13
A novel allogeneic acellular matrix scaffold for porcine cartilage regeneration	13
Isolation and identification of antifungal, antibacterial and nematocide agents from marine bacillus gottheilii MSB1	13
Gene cloning and molecular characterization of a thermostable chitosanase from Bacillus cereus TY24	13
Aripiprazole-loaded niosome/chitosan-gold nanoparticles for breast cancer chemo-photo therapy	12
A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana	12
In silico screening and in vitro biological evaluation reveal Queuine as a promising MAP4K4 inhibitor for treating pancreatic cancer	12
Efficient delivery of a large-size Cas9-EGFP vector in porcine fetal fibroblasts using a Lonza 4D-Nucleofector system	11
Derivation of a novel antimicrobial peptide from the Red Sea Brine Pools modified to enhance its anticancer activity against U2OS cells	11
Validation and calibration of a novel GEM biosensor for specific detection of Cd2+, Zn2+, and Pb2+	11
An engineered hypoxia-response promoter for human umbilical cord-derived mesenchymal stem cell-based therapeutics	11
Saccharification and co-fermentation of lignocellulosic biomass by a cockroach-gut bacterial symbiont and yeast cocktail for bioethanol production	11
A magnetic solid phase chemiluminescent immunoassay for quantification of Cystatin C in human serum	11
Unlocking the antioxidant and antibacterial potential of exopolysaccharides produced by endophytic fungi (Aspergillus fumigatus and Preussia isabellae) isolated from Tanzania’s mangroves	11
ECM-mimetic, NSAIDs loaded thermo-responsive, immunomodulatory hydrogel for rheumatoid arthritis treatment	11
Development of a CHO cell line for stable production of recombinant antibodies against human MMP9	10
Ferula latisecta gels for synthesis of zinc/silver binary nanoparticles: antibacterial effects against gram-negative and gram-positive bacteria and physicochemical characteristics	10
Dexamethasone-boosted mesenchymal stem cell secretome: insight into hepatic protection	10
Aspergillus terreus camptothecin-sodium alginate/titanium dioxide nanoparticles as a novel nanocomposite with enhanced compatibility and anticancer efficiency in vivo	10
Enhancing the biotransformation of progesterone to the anticancer compound testololactone by Penicillium chrysogenum Ras3009: kinetic modelling and efficiency maximization	10
Establishment of an indirect ELISA antibody detection method based on the stable expression of LSDV P32 protein in CHO-K1 cells	9
Organosolv-derived lipids from hemicellulose and cellulose, and pre-extracted tannins as additives upon hydrothermal liquefaction (HTL) of spruce bark lignins to bio-oil	9
An efficient and specific CRISPR-Cas9 genome editing system targeting soybean phytoene desaturase genes	9
Fabrication of apigenin and adenosine-loaded nanoparticles against doxorubicin-induced myocardial infarction by reducing inflammation and oxidative stress	9
High-performance internal circulation anaerobic granular sludge reactor for cattle slaughterhouse wastewater treatment and simultaneous biogas production	9
Green and environmentally friendly synthesis of silver nanoparticles with antibacterial properties from some medicinal plants	9
Rescue of an enterotropic Newcastle disease virus strain ZM10 from cloned cDNA and stable expressing an inserted foreign gene	9
Coupling fermentation of glutamic acid and γ-polyglutamic acid and preparation of poly(amino acid) superabsorbent polymers	8
A novel starch-active lytic polysaccharide monooxygenase discovered with bioinformatics screening and its application in textile desizing	8
Exploring the microbial diversity and characterization of cellulase and hemicellulase genes in goat rumen: a metagenomic approach	8
An anti-idiotypic single domain antibody as Cry2Aa toxin mimotope and analysis of its binding region through molecular docking	8
Utilizing non-clonal CHO cell derived materials for preclinical studies of complex molecules	8
Antifungal efficacy of Citrusfusion mediated silver nanoparticles in Candida species	8
Synthesis and evaluation of nanosized aluminum MOF encapsulating Umbelliferon: assessing antioxidant, anti-inflammatory, and wound healing potential in an earthworm model	8
Assessment of the bioactive compounds in gamma irradiated stevia (Stevia rebaudiana Bertoni) leaves	8
Efficient extraction and antioxidant activity of polyphenols from Antrodia cinnamomea	7
Comparison of active site mutations at subsite + 2 of Anoxybacillus ayderensis A9 β-glucosidase for hydrolysis of pNPG and polydatin	7
Scientific and technological challenges of recombinant egg protein production	7

The transcriptional factor Clr-5 is involved in cellulose degradation through regulation of amino acid metabolism in Neurospora crassa	7
Bioconversion of wild Ipomoea pes-caprae and Suaeda fruticosa biomass: a novel application of thermostable xylanase from Neobacillus sedimentimangrovi	7
Dual release of daptomycin and BMP-2 from a composite of β-TCP ceramic and ADA gelatin	7
Optimization of culture conditions for HBV-specific T cell expansion in vitro from chronically infected patients	7
Oleic acid based experimental evolution of Bacillus megaterium yielding an enhanced P450 BM3 variant	7
Development of a chemically defined medium for Paenibacillus polymyxa by parallel online monitoring of the respiration activity in microtiter plates	7
Orange peel-mediated synthesis of silver nanoparticles with antioxidant and antitumor activities	7
An engineered self-cleavage fusion system for the production of chimaera spider silk proteins	7
Integration of ZnO nanorods with silver ions by a facile co-precipitation for antimicrobial, larvicidal, and ovicidal activity	7
Enhanced extracellular production of Coprinopsis cinerea laccase Lcc9 in Aspergillus niger by gene expression cassette and bioprocess optimization	7
Effects of solid lipid nanocarrier containing methyl urolithin A by coating folate-bound chitosan and evaluation of its anti-cancer activity	7
Research on the targeted improvement of the yield of a new VB12-producing strain, Ensifer adhaerens S305, based on genomic and transcriptomic analysis	6
Unraveling the impact of pH, sodium concentration, and medium osmolality on Vibrio natriegens in batch processes	6
Self-assembling T7 phage syringes with modular genomes for targeted delivery of penicillin against β-lactam-resistant Escherichia coli	6
rocF affects the production of tetramethylpyrazine in fermented soybeans with Bacillus subtilis BJ3-2	6
Identification, expression, and purification of DNA cytosine 5-methyltransferases with short recognition sequences	6
Prediction and optimization of indirect shoot regeneration of Passiflora caerulea using machine learning and optimization algorithms	6
Introduction of loxP sites by electroporation in the mouse genome; a simple approach for conditional allele generation in complex targeting loci	6
Probiotic, antimicrobial and anticancer properties of Lysinibacillus macroides, Kurthia huakuii, and Enterococcus faecium isolated from freshwater snail gut microbiota	6
Microarray-based evaluation of selected recombinant timothy grass allergens expressed in E. Coli and N. Benthamiana	6
Development of a chemiluminescence assay for tissue plasminogen activator inhibitor complex and its applicability to gastric cancer	6
Preparation and characterization of propolis reinforced eggshell membrane/ GelMA composite hydrogel for biomedical applications	6
Assessment of biochar filter application in improving chromium stress tolerance and plant physiology in Chinese cabbage (Brassica rapa) under a flow-through water setup	6
Induction of antimicrobial, antioxidant metabolites production by co-cultivation of two red-sea-sponge-associated Aspergillus sp. CO2 and Bacillus sp. COBZ21	6
Metabolomics-based analysis of the correlation between lipid metabolites and thyroid carcinoma	6
Correction: Purification, characterization, and anti-cancer activity of methionine gamma-lyase from a native strain of Pseudomonas mosselii for human cancer treatment	6
Choosing an appropriate somatic embryogenesis medium of carrot (Daucus carota L.) by data mining technology	6
Influence of low-intensity artificial light on the fatty acid profile of the biotechnologically important culinary mushroom Pleurotus eryngii in vitro	6
Design, synthesis, and biological evaluation of Osimertinib–Cy7 (OSA-Cy7) conjugate as potential theranostic agent targeting activating EGFR mutations	6
Biogenic silver nanoparticles synthesized from Pseudomonas fluorescens-mediated olive cake waste: antimicrobial, larvicidal activity against Culex pipiens and cytotoxicity assessment	5
Early osteogenic differentiation of human dental stem cells by gelatin/calcium phosphate- Punica granatum nanocomposite scaffold	5
Strain-specific features of Pleurotus ostreatus growth in vitro and some of its biological activities	5
Efficient gene delivery into the embryonic chicken brain using neuron-specific promoters and in ovo electroporation	5
Effect of different decellularization protocols on reendothelialization with human cells for a perfused renal bioscaffold of the rat	5
E7 peptide and magnesium oxide-functionalized coaxial fibre membranes enhance the recruitment of bone marrow mesenchymal stem cells and promote bone regeneration	5
Antimicrobial, antidiabetic, antiviral, and antioxidant activities of fucoidan extracted from the brown seaweed Padina pavonica	5
Uncovering the potential of biofabricated Ananas comosus peel selenium nanoparticles for antibacterial, antibiofilm, suppression of virulence genes (can and LuxS), anticancer, and antioxidant properti	5
Purification, characterization, and anti-cancer activity of methionine gamma-lyase from a native strain of Pseudomonas mosselii for human cancer treatment	5
Evaluation of the pharmacological potential of Ganoderma lucidum against haemorrhagic and anticoagulant activities of Echis ocellatus venom	5
MiR-125b-5p ameliorates ox-LDL-induced vascular endothelial cell dysfunction by negatively regulating TNFSF4/TLR4/NF-κB signaling	5
Improving the regeneration rate of deep lethal mutant protoplasts by fusion to promote efficient L-lysine fermentation	5
Development of Virus-Like Particles (VLPs) for Hepatitis C Virus genotype 4: a novel approach for vaccine development in Egypt	5
Green synthesis of silver nanoparticles using cocoon extract of Bombyx mori L.: therapeutic potential in antibacterial, antioxidant, anti-inflammatory, and anti-tumor applications	5
Toxic effects of trace phenol/guanidine isothiocyanate (P/GI) on cells cultured nearby in covered 96-well plates	5
Comparison of lipidome profiles in serum from lactating dairy cows supplemented with Acremonium terrestris culture based on UPLC-QTRAP-MS/MS	5
In vitro evaluation of PLGA loaded hesperidin on colorectal cancer cell lines: an insight into nano delivery system	5
Online monitoring of the mitochondrial respiration activity and protein formation in the Almost Living Cell-free Expression (ALiCE) system	5
Antibacterial and antibiofilm potentials of vancomycin-loaded niosomal drug delivery system against methicillin-resistant Staphylococcus aureus (MRSA) infections	5
Determination of serum CA724 levels using fluorescence immunochromatography	5
Modeling and optimizing in vitro percentage and speed callus induction of carrot via Multilayer Perceptron-Single point discrete GA and radial basis function	5
Antifungal, toxicological, and colorimetric properties of Origanum vulgare, Moringa oleifera, and Cinnamomum verum essential oils mixture against Egyptian Prince Yusuf Palace deteriorative fungi	4
Adsorption of Hg2+/Cr6+ by metal-binding proteins heterologously expressed in Escherichia coli	4
Biodegradation of patulin in apple juice by phosphoribosyl transferase (URA5): implications for food safety	4
UGT708S6 from Dendrobium catenatum, catalyzes the formation of flavonoid C-glycosides	4
Optimization, characterization and biosafety of carotenoids produced from whey using Micrococcus luteus	4
An online soft sensor method for biochemical reaction process based on JS-ISSA-XGBoost	4
Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa	4
A cleavable peptide adapter augments the activity of targeted toxins in combination with the glycosidic endosomal escape enhancer SO1861	4
Extract optimization and biological activities of Otidea onotica using Artificial Neural Network-Genetic Algorithm and response surface methodology techniques	4
Enhanced vitamin B12 production by isolated Bacillus strains with the application of response surface methodology	4
Statistical optimization of pectinases from thermophilic Aspergillus fumigatus BT-4 employing response surface methodology through submerged fermentation using agricultural wastes	4
Impacts of loading thymoquinone to gold or silver nanoparticles on the efficacy of anti-tumor treatments in breast cancer with or without chemotherapeutic cisplatin	4
Analysis of hsa_circ_0136256 as a biomarker for fibrosis in systemic sclerosis	4
Use of immunoinformatics and the simulation approach to identify Helicobacter pylori epitopes to design a multi-epitope subunit vaccine for B- and T-cells	4
Production of rhamnolipid biosurfactants in solid-state fermentation: process optimization and characterization studies	3
Correction: Transcriptomic and targeted metabolomic analyses provide insights into the flavonoids biosynthesis in the flowers of Lonicera macranthoides	3
Production of SARS-CoV-2 virus-like particles as a vaccine candidate in stable cell lines through inducible E and M protein expression	3
Identification and characterization of sugar-regulated promoters in Chaetomium thermophilum	3
N-Acetylcysteine as an anti-oxidant and anti-inflammatory agent in decreasing histopathological damages and oxidative stress after mercury exposure in lung tissue of rats	3
Transcriptomic and targeted metabolomic analyses provide insights into the flavonoids biosynthesis in the flowers of Lonicera macranthoides	3
Metabolic studies of Ogataea polymorpha using nine different corn steep liquors	3
A solution for highly efficient electroporation of primary cytotoxic T lymphocytes	3
Nitric oxide mediates positive regulation of Nostoc flagelliforme polysaccharide yield via potential S-nitrosylation of G6PDH and UGDH	3
Sustainable biodiesel production from agricultural lignocellulosic waste via oleaginous microbial processes	3
Artificial Neural Network - Multi-Objective Genetic Algorithm based optimization for the enhanced pigment accumulation in Synechocystis sp. PCC 6803	3
Multiprotein collagen/keratin hydrogel promoted myogenesis and angiogenesis of injured skeletal muscles in a mouse model	3
Chemical and Heat Treatment for Viral Inactivation in Porcine-Derived Gelatin	3
Lipid extraction and analysis of microalgae strain pectinodesmus PHM3 for biodiesel production	3
Kinetics of cellulase-free endo xylanase hyper-synthesis by Aspergillus Niger using wheat bran as a potential solid substrate	3
Exploring the mechanisms and mode of action of bioactive compounds from marine Streptomyces albidoflavus against breast carcinoma cells	3

Effect of liquefaction temperature and enzymatic treatment on bioethanol production from mixed waste baked products	3
Anticancer effects of folic acid-functionalized covalent organic framework containing doxorubicin on SW480 colon cancer cells: a promising tool for drug targeted delivery	3
Self-limiting fall armyworm: a new approach in development for sustainable crop protection and resistance management	3
An effective device to enable consistent scratches for in vitro scratch assays	3
Comparative evaluation of various DNA extraction methods and analysis of DNA degradation levels in commercially marketed Chestnut rose juices and beverages	3
A simplified Gibson assembly method for site directed mutagenesis by re-use of standard, and entirely complementary, mutagenesis primers	2
In vitro assessment of the effect of magnetic fields on efficacy of biosynthesized selenium nanoparticles by Alborzia kermanshahica	2
Screening of Candida spp. in wastewater in Brazil during COVID-19 pandemic: workflow for monitoring fungal pathogens	2
Development of a chemiluminescent immunoassay based on magnetic solid phase for quantification of homocysteine in human serum	2
Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform	2
The role of Genipin crosslinked extracellular matrix loaded bFGF in the repair of peripheral nerve injury	2
Rapidly decellularized adipose tissue induces soft tissue vascularization in potential anatomical spaces	2
Antifungal screening of selenium nanoparticles biosynthesized by microcystin-producing Desmonostoc alborizicum	2
Interaction of potato-derived RG-I with galectin-3 and gene regulation in human mesenchymal stem cells	2
Suppression of mycotoxins production and efficient chelation of heavy metals using natural melanin originated from Aspergillus flavus and Aspergillus carbonarius	2
αvβ3-targeted sEVs for efficient intracellular delivery of proteins using MFG-E8	2
Modification of improved-genome editing via oviductal nucleic acids delivery (i-GONAD)-mediated knock-in in rats	2
How thyme thrives under drought: insights into photosynthetic and membrane-protective mechanisms	2
Antifungal activity and biocompatibility assessment with molecular docking and dynamic simulations of new pyrazole derivatives	2
Extract optimization of Ulva lactuca L. and biological activities of optimized extracts	2
Design of a novel multi-epitope vaccine against Marburg virus using immunoinformatics studies	2
Optimisation of indole acetic acid production by Neopestalotiopsis aotearoa endophyte isolated from Thymus vulgaris and its impact on seed germination of Ocimum basilicum	2
Serodiagnosis of human brucellosis by an indirect ELISA test using recombinant outer membrane protein 19 kDa (rOMP19) as an antigen	2
Genome-wide identification and diversity of FAD2, FAD3 and FAE1 genes in terms of biotechnological importance in Camelina species	2
Limonene encapsulated alginate/collagen as antibiofilm drug against Acinetobacter baumannii	2
Design of a new lyoprotectant increasing freeze-dried Lactobacillus strain survival to long-term storage	2
Investigation of neomycin biodegradation conditions using ericoid mycorrhizal and white rot fungal species	2
Antibacterial, antibiofilm, and anticancer activity of silver-nanoparticles synthesized from the cell-filtrate of Streptomyces enissocaesilis	2
Solubility of lamotrigine in age-specific biorelevant media that simulated the fasted- and fed-conditions of the gastric and intestinal environments in pediatrics and adults: implications for traditio	2
A new antifungal compound from Streptomyces diastatochromogenes	2
Fermentation of Asparagus cochinchinensis extracts with endophytic Aspergillus aculeatus TD103 enhanced their photo-protective effects against UVB radiation	2
A study on the processing technology for Rhizoma Coptidis	2
The impact of applying various de novo assembly and correction tools on the identification of genome characterization, drug resistance, and virulence factors of clinical isolates using ONT sequencing	2
Recombinant human enamelin produced in Escherichia coli promotes mineralization in vitro	2
Potential protective efficacy of biogenic silver nanoparticles synthesised from earthworm extract in a septic mice model	2
Metabolic engineering for microbial production of sugar acids	2