OOIR: Observatory of International Research

Papers

(The TQCC of BMC Biotechnology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Optimized culture conditions for bacterial cellulose production by Acetobacter senegalensis MA1	61
Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope	57
Loop-mediated isothermal amplification (LAMP) reaction as viable PCR substitute for diagnostic applications: a comparative analysis study of LAMP, conventional PCR, nested PCR (nPCR) and real-time PCR	56
Optimization and scale-up of α-amylase production by Aspergillus oryzae using solid-state fermentation of edible oil cakes	54
Generation of transgene-free PDS mutants in potato by Agrobacterium-mediated transformation	49
The osteogenic differentiation of human dental pulp stem cells in alginate-gelatin/Nano-hydroxyapatite microcapsules	43
Efficient CRISPR/Cas9 genome editing in a salmonid fish cell line using a lentivirus delivery system	37
A novel high performance in-silico screened metagenome-derived alkali-thermostable endo-β-1,4-glucanase for lignocellulosic biomass hydrolysis in the harsh conditions	35
Antibacterial effect of cerium oxide nanoparticle against Pseudomonas aeruginosa	33
Repurposing novel therapeutic candidate drugs for coronavirus disease-19 based on protein-protein interaction network analysis	29
Efficient generation of GGTA1-deficient pigs by electroporation of the CRISPR/Cas9 system into in vitro-fertilized zygotes	28
Efficient CRISPR/Cas9 genome editing with Citrus embryogenic cell cultures	28
Comparing various protocols of human and bovine ovarian tissue decellularization to prepare extracellular matrix-alginate scaffold for better follicle development in vitro	26
GoldenBac: a simple, highly efficient, and widely applicable system for construction of multi-gene expression vectors for use with the baculovirus expression vector system	25
An efficient and specific CRISPR-Cas9 genome editing system targeting soybean phytoene desaturase genes	24
The study of laccase immobilization optimization and stability improvement on CTAB-KOH modified biochar	22
Development of a method for phycocyanin recovery from filamentous cyanobacteria and evaluation of its stability and antioxidant capacity	22
Bacillus sp. CSK2 produced thermostable alkaline keratinase using agro-wastes: keratinolytic enzyme characterization	21
A prospectus of plant growth promoting endophytic bacterium from orchid (Vanda cristata)	20
Characterization and genomic analysis of a diesel-degrading bacterium, Acinetobacter calcoaceticus CA16, isolated from Canadian soil	20
Combined pretreatment of sugarcane bagasse using alkali and ionic liquid to increase hemicellulose content and xylanase production	20
Lyso-phosphatidylethanolamine primes the plant immune system and promotes basal resistance against hemibiotrophic pathogens	20
Screening of five marine-derived fungal strains for their potential to produce oxidases with laccase activities suitable for biotechnological applications	20
A copper switch for inducing CRISPR/Cas9-based transcriptional activation tightly regulates gene expression in Nicotiana benthamiana	19
Process optimization and effect of thermal, alkaline, H2O2 oxidation and combination pretreatment of sewage sludge on solubilization and anaerobic digestion	18

CRISPR/Cas9-mediated knockout of clinically relevant alloantigenes in human primary T cells	18
Heterologous expression of nattokinase from B. subtilis natto using Pichia pastoris GS115 and assessment of its thrombolytic activity	17
Tofu processing wastewater as a low-cost substrate for high activity nattokinase production using Bacillus subtilis	17
Levan from Leuconostoc citreum BD1707: production optimization and changes in molecular weight distribution during cultivation	17
Attenuation of intestinal inflammation in IL-10 deficient mice by a plasmid carrying Lactococcus lactis strain	17
Design of a new lyoprotectant increasing freeze-dried Lactobacillus strain survival to long-term storage	16
Rational design and structure-based engineering of alkaline pectate lyase from Paenibacillus sp. 0602 to improve thermostability	16
Tenebrio molitor: possible source of polystyrene-degrading bacteria	14
Evaluation of RNA isolation methods for microRNA quantification in a range of clinical biofluids	14
Production of surfactant-stable keratinase from Bacillus cereus YQ15 and its application as detergent additive	14
Vitrification for cryopreservation of 2D and 3D stem cells culture using high concentration of cryoprotective agents	13
Different genome-wide transcriptome responses of Nocardioides simplex VKM Ac-2033D to phytosterol and cortisone 21-acetate	13
Isolation and identification of a feather degrading Bacillus tropicus strain Gxun-17 from marine environment and its enzyme characteristics	13
Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation	13
Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate	12
Evaluating the biocontrol potential of Canadian strain Bacillus velezensis 1B-23 via its surfactin production at various pHs and temperatures	12
Isolation of axenic cyanobacterium and the promoting effect of associated bacterium on axenic cyanobacterium	12
An effective combination of codon optimization, gene dosage, and process optimization for high-level production of fibrinolytic enzyme in Komagataella phaffii (Pichia pastoris)	12
Self-limiting fall armyworm: a new approach in development for sustainable crop protection and resistance management	11
High level expression and biochemical characterization of an alkaline serine protease from Geobacillus stearothermophilus to prepare antihypertensive whey protein hydrolysate	11
Mining of two novel aldehyde dehydrogenases (DHY-SC-VUT5 and DHY-G-VUT7) from metagenome of hydrocarbon contaminated soils	11
Optimization of lipase production using fungal isolates from oily residues	11
An improved quantitative real-time polymerase chain reaction technology for Helicobacter pylori detection in stomach tissue and its application value in clinical precision testing	11
One-step fermentation for producing xylo-oligosaccharides from wheat bran by recombinant Escherichia coli containing an alkaline xylanase	11
Gelatin nanoparticles enable water dispersibility and potentialize the antimicrobial activity of Buriti (Mauritia flexuosa) oil	10
Screening of miRNAs in plasma as a diagnostic biomarker for cardiac disease based on optimization of extraction and qRT-PCR condition assay through amplification efficiency	10
Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures	10
Recombinant laccase rPOXA 1B real-time, accelerated and molecular dynamics stability study	10
Comparative gene expression profiling of mouse ovaries upon stimulation with natural equine chorionic gonadotropin (N-eCG) and tethered recombinant-eCG (R-eCG)	9
Synergistic interaction of hTGF-β3 with hBMP-6 promotes articular cartilage formation in chitosan scaffolds with hADSCs: implications for regenerative medicine	9
Development of a CRISPR/Cpf1 system for targeted gene disruption in Aspergillus aculeatus TBRC 277	9
Development of a human phage display-derived anti-PD-1 scFv antibody: an attractive tool for immune checkpoint therapy	9
Effects of early geometric confinement on the transcriptomic profile of human cerebral organoids	9
The mechanism of degradation of alizarin red by a white-rot fungus Trametes gibbosa	9