OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Neurotherapeutics is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Does electrical stimulation still have a place in the treatment armamentarium for Bell’s palsy?	46
How have the recent updated epilepsy classifications impacted on diagnosis and treatment?	42
The role of Fecal Microbiota Transplantation (FMT) in treating patients with multiple sclerosis	38
Neonatal seizures treatment based on conventional multichannel EEG monitoring: an overview of therapeutic options	36
Profiling deutetrabenazine extended-release tablets for tardive dyskinesia and chorea associated with Huntington’s disease	34
An overview of the differences in the pharmacological management of post-traumatic stress disorder between women and men	31
The latest developments with internet-based psychological treatments for depression	30
Laser interstitial thermal therapy for recurrent brain metastases following stereotactic radiosurgery: a systematic review	29
The relevance of cortical thickness in migraine sufferers and implications to therapy	28
Determining minimally clinically important differences for outcome measures in patients with chronic motor deficits secondary to traumatic brain injury	27
Where Art Thou O treatment for diabetic neuropathy: the sequel	27
Ultrasensitive techniques and protein misfolding amplification assays for biomarker-guided reconceptualization of Alzheimer’s and other neurodegenerative diseases	25
Immunomodulatory effects and clinical benefits of intravenous immunoglobulin in myasthenia gravis	24
The influence of anxiety and depression on headache in adolescent migraineurs: a case-control study	24
Neuroprotective strategies in multiple sclerosis: a status update and emerging paradigms	23
Advances in the treatment and management of frontotemporal dementia	22
Viloxazine extended-release capsules as an emerging treatment for attention-deficit/hyperactivity disorder in children and adolescents	21
The current status of somatostatin analogs in the treatment of neuroendocrine tumors and future perspectives	21
Uncertainties in anti-amyloid monoclonal antibody therapy for Alzheimer’s disease: the challenges ahead	21
Updated review on the link between cortical spreading depression and headache disorders	21
Why is ADHD so difficult to diagnose in older adults?	21
Managing antipsychotic-related sexual dysfunction in patients with schizophrenia	20
Acute and long-term cognitive impairment following sepsis: mechanism and prevention	20
Post Intensive Care Syndrome (PICS): an overview of the definition, etiology, risk factors, and possible counseling and treatment strategies	19
Correction	19

An overview of ganaxolone as a treatment for seizures associated with cyclin-dependent kinase-like 5 deficiency disorder	19
Advances in the early diagnosis of amyotrophic lateral sclerosis	18
Hesitancies in primary headaches treatments	18
Treating subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: an update of the literature	18
Diagnosing epileptic seizures in patients with Alzheimer’s disease and deciding on the appropriate treatment plan	17
Spinal automaticity of movement control and its role in recovering function after spinal injury	17
Mindfulness as a therapeutic option for obsessive-compulsive disorder	17
Current and emerging diagnostic and management approaches for idiopathic intracranial hypertension	17
Clinical Insights and Strategies to Managing Depression Subtypes Associated with Tobacco dependence: A Response to the Letter to the Editor	17
Current perspectives on the diagnosis, assessment, and management of vasculitic neuropathy	16
An update on the pharmacological management of Tourette syndrome and emerging treatment paradigms	16
Advances in gene therapy for high-grade glioma: a review of the clinical evidence	16
Distinguishing essential tremor from Parkinson’s disease: clinical and experimental tools	16
The differential diagnosis of autism spectrum disorder in adults	16
Comparison of the retention rate, safety, and efficacy of two different titration protocols for lamotrigine in newly diagnosed epilepsy patients	16
Virtual reality technology in the treatment of anxiety – progress and future challenges	15
Essential Tremor – Deep Brain Stimulation vs. Focused Ultrasound	15
Multimodal approaches to the treatment of personality disorder	15
Illuminating the way: the role of bright light therapy in the treatment of depression	14
Efficacy and safety of vigabatrin in patients with tuberous sclerosis complex and infantile epileptic spasm syndrome: a systematic review	14
Current use of neurotoxins for alleviating symptoms of cervical dystonia	14
Cross-national reflections on medicinal cannabis and depression	13
Evaluating the value and risks of psychedelics for psychiatric medicine: a clinical perspective	13
Revisiting stimulant use for emotional dysregulation in attention-deficit/hyperactivity disorder (ADHD)	13
Psychotherapeutic treatments for generalized anxiety disorder: cognitive and behavioral therapies, enhancement strategies, and emerging efforts	13
Considerations for hormonal therapy in migraine patients: a critical review of current practice	13
A novel treatment option for intrajejunal levodopa administration	13
Considering hearing loss as a modifiable risk factor for dementia	13
Frontotemporal dementia. How to deal with its diagnostic complexity?	12
Trends in disease-modifying therapy use in patients with multiple sclerosis using a 10-year population-based cohort study in France	12
Using oral topiramate for primary generalized and focal-to-bilateral tonic-clonic seizures in patients 2 years of age and older: a review of the literature	12
Persistent post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies	12
Advancements in neuroactive peptides in seizures	12
An updated review on the role of prescribed exercise in the management of Amyotrophic lateral sclerosis	12
Long-term outcomes in refractory status epilepticus	12
Updated review of rescue treatments for seizure clusters and prolonged seizures	11
Therapeutic issues in Guillain–Barré syndrome	11
Managing impulse control and related behavioral disorders in Parkinson’s disease: where we are in 2025?	11
A critical review of incobotulinumtoxinA in the treatment of chronic sialorrhea in pediatric patients	11
Retinal optical coherence tomography and magnetic resonance imaging in neuromyelitis optica spectrum disorders and MOG-antibody associated disorders: an updated review	11
Imaging protocols for non-traumatic spinal cord injury: current state of the art and future directions	11
The effectiveness of electroconvulsive therapy (ECT) for people with bipolar disorder: is there a specific role?	11
Developments in the prediction of cognitive changes following deep brain stimulation in persons with Parkinson’s disease	11
Current perspectives on the recognition and diagnosis of low CSF pressure headache syndromes	11
Radiosurgical thalamotomy for essential tremor: state of the art, current challenges and future directions	11
Profiling aducanumab as a treatment option for Alzheimer’s disease: an overview of efficacy, safety and tolerability	11
Developments in targeting calcitonin gene-related peptide	10
An update on the role of magnetic resonance imaging in predicting and monitoring multiple sclerosis progression	10
Could self-reporting sleep duration become an important tool in the prediction of dementia?	10
Teriflunomide: an oral therapy for first-line treatment of children and adolescents living with relapsing-remitting multiple sclerosis	10

Family accommodation: a diagnostic feature of obsessive-compulsive disorder?	10
Bipolar disorder staging and the impact it has on its management: an update	10
Combinations of dextromethorphan for the treatment of mood disorders - a review of the evidence	10
Efficacy analysis of three brain stimulation techniques for Alzheimer’s disease: a meta-analysis of repeated transcranial magnetic stimulation, transcranial direct current stimulation, and deep brain	10
Why lithium should be used in patients with bipolar disorder? A scoping review and an expert opinion paper	10
Meniere disease subtyping: the direction of diagnosis and treatment in the future	9
What is the potential of paramagnetic rim lesions as diagnostic indicators in multiple sclerosis?	9
Long-term central nervous system (CNS) consequences of COVID-19 in children	9
Rethinking the role of trazodone in the different depressive dimensions	9
Cognitive or daily stress association with headache and pain induction in migraine and tension-type headache patients: a systematic review	9
Omaveloxolone for the treatment of Friedreich ataxia: clinical trial results and practical considerations	9
A review of a diazepam nasal spray for the treatment of acute seizure clusters and prolonged seizures	9
Imaging of infectious and inflammatory cystic lesions of the brain, a narrative review	9
Pharmacological and non-pharmacological treatment options for sleep disturbances in Alzheimer’s disease	9
Pharmacotherapy of schizophrenia: immunological aspects and potential role of immunotherapy	9
Pharmacological Treatment of Generalised Anxiety Disorder: Current Practice and Future Directions	9
The pivotal role of central sensitization in long COVID, fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome	9
Neuromodulation as a treatment strategy in Lennox-Gastaut syndrome: evidence and future directions	9
Risk of suicide and suicide-related events in subjects treated with antiseizure medications	8
Ublituximab-xiiy as a treatment option for relapsing multiple sclerosis	8
The benefits and risks of escalation versus early highly effective treatment in patients with multiple sclerosis	8
The challenges and opportunities related to the therapeutic use of music in psychiatry	8
Sydenham’s chorea: from pathophysiology to therapeutics	8
Practical pearls to improve the efficacy and tolerability of levodopa in Parkinson’s disease	8
Combination of noninvasive brain stimulation and constraint-induced movement therapy in patients with stroke: a systematic review and meta-analysis	8
Tobacco use disorder and depression: emerging strategies and recommendations:	8
Re-evaluating the prognosis of schizophrenia: tackling the issue of inadequate treatment	8
Insulin signaling in the central nervous system, a possible pathophysiological mechanism of anesthesia-induced delayed neurocognitive recovery/postoperative neurocognitive disorder: a narrative review	8
The complexities in the differential diagnosis of restless legs syndrome (Willis–Ekbom disease)	8
What are the main challenges in the treatment of neonatal hypoxic ischemic encephalopathy?	8
Contemporary perspectives in cerebral amyloid angiopathy	8
Learnings in developmental and epileptic encephalopathies: what do we know?	8
The major challenges with pharmacologic management of chronic traumatic encephalopathy	8
Olanzapine-samidorphan combination tablets for the treatment of schizophrenia and bipolar I disorder - what is it, and will it be used?	8
Deep brain stimulation: new programming algorithms and teleprogramming	8