Nature Reviews Immunology

Article	Citations
Regulation goes awry in the liver	907
Heart failure affects innate immune memory	795
Comparing neurological complications after COVID-19 vaccination and SARS-CoV-2 infection	646
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	634
Early life antibiotics have lasting effects on the lung epithelium	587
BCG plus β-glucan trains neutrophils to beat bladder cancer	553
The danger theory of immunity revisited	545
The immunology of asthma and chronic rhinosinusitis	436
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis	396
Viral infection and antiviral immunity in the oral cavity	376
Decoding the human prenatal immune system with single-cell multi-omics	371
Human immune organoids: a tool to study vaccine responses	326
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses	326
Vaccines only partially protect against Long COVID	310
Challenges in developing personalized neoantigen cancer vaccines	301
Muscle spindle macrophages regulate motor coordination	299
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses	298
Regulation of cGAS–STING signalling and its diversity of cellular outcomes	275
Stressed tumours release immunosuppressive vesicles	272
Omicron alone provides limited cross-protection	267
Gut commensals promote antiviral immunity via extracellular vesicles	266
Targeting malaria transmission	259
Lessons from vaccine-induced immune thrombotic thrombocytopenia	257
Novel insights into the immune response to bacterial T cell superantigens	255
The distinctive immune features of long COVID	254

Human T follicular regulatory cells with helper and regulatory lineage origins	252
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells	244
Neutrophils are dispensable for Shigella control: macrophages take centre stage	241
Antiviral neutralizing antibodies: from in vitro to in vivo activity	223
The NLR gene family: from discovery to present day	218
How bile acids and the microbiota interact to shape host immunity	216
Encouraging vaccine uptake: lessons from behavioural science	208
A guide to adaptive immune memory	198
Mechanistic insights from inflammasome structures	198
B cells in central nervous system disease: diversity, locations and pathophysiology	195
Salt sensitivity includes effects on immune cell signalling and metabolism	188
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer	188
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells	188
You are what you ate: myeloid cells trained by fatty acids	173
Bile duct tuft cells regulate immune defences	163
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells	162
T cell–eosinophil collaboration	162
Gut ILC2s remember IL-25	161
Author Correction: SARS-CoV-2 and HIV-1 – A Tale of Two Vaccines	160
Online immunology education for a global world	152
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC	152
APOL1 variants contribute to racial disparity in sepsis	151
The OrganiX microfluidic system to recreate the complex tumour microenvironment	149
Cross reactive T cells hold up against Omicron	144
The cancer-immune dialogue in the context of stress	143
Splenic stromal niches in homeostasis and immunity	142
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease	136
The germinal centre B cell response to SARS-CoV-2	135
Bacteria in tumours promote cancer progression	131
Feeding IgA+ plasma cells	131
JAKs drive innate-like TH9 cell activation in allergy	131
Negative regulation of fungal immunity by STING	130
Mechanistic insights into Long COVID in hamsters	129
Spatial resolution of host–microbiome interactions	128
Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses	128
Low risk of CAR T cells going rogue	127
Monocytes rule energy metabolism with an iron fist	123
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint	123
Neutrophils make matrix to fortify barrier immunity	120
The immunopathogenesis of narcolepsy type 1	117
Author Correction: Cancer cell metabolism and antitumour immunity	113
The spatial and temporal activation of macrophages during fibrosis	113
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	111
Olfactory immunology: the missing piece in airway and CNS defence	111
The biology of TREM receptors	111
Lessons in self-defence: inhibition of virus entry by intrinsic immunity	111
The interplay of immunology and cachexia in infection and cancer	104
Monkeypox: disease epidemiology, host immunity and clinical interventions	103
Rejuvenation through checkpoint inhibitors?	100
A guide to antigen processing and presentation	100

T cells target viral protein to remove senescent fibroblasts	99
Foetal sex affects maternal and placental immune responses to SARS-CoV-2	94
Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?	92
Commensal fungi support granulocyte development	92
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy	91
Guardians of immune privilege	90
Podoplanin mediates stromal–immune crosstalk in the lymph node	90
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases	89
We need to keep an eye on avian influenza	85
DNA damage and repair in age-related inflammation	85
mRNA vaccine for treating pancreatic cancer	83
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells	80
Local immune recognition of trophoblast in early human pregnancy: controversies and questions	80
Glomerulonephritis: immunopathogenesis and immunotherapy	78
Spatial immunometabolic zonation in tuberculosis granulomas	78
Pollution impairs lung defences with age	77
Bacterial serotonin induces Treg cells in neonates	75
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis	74
γδ T cells sense disturbance	74
Boosting cytotoxic T cells for immunotherapy	73
Microbiota licenses protective CD8+ T cell responses against neonatal influenza	72
Actin branching maintains tissue-resident mast cells	69
Insights into immune cell–fibroblast communication in heart disease	68
Asymptomatic SARS-CoV-2 linked to HLA-B*15:01	67
Hypoxia and IL-24 drive a sterile wound healing pathway	64
Early antiviral type I interferon impairs lung metastasis	63
Lung-resident memory B cells class-switch to IgE	62
Integrated organ immunity: a path to a universal vaccine	62
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection	60
The renaissance of oral tolerance: merging tradition and new insights	59
Turning on anti-tumour T cells via MTAP	58
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases	57
CODEX multiplexed tissue imaging	56
Defining myeloid-derived suppressor cells	56
IL-17 and IL-17-producing cells in protection versus pathology	55
First glimpses into the mechanisms of Long COVID	53
Effect of prenatal stress on the developing brain	52
The autoinflammatory disease APLAID is driven by G-CSF	50
Author Correction: The immunology of long COVID	49
A pan-cancer signature for dysfunctional T cells	48
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis	47
When ‘mild’ COVID-19 is not so mild	46
PerturbView: scalable image-based perturbation screens in cells and tissues	44
Bacteria tag tumours for CAR T cell attack	44
B cell-derived acetylcholine curbs haematopoiesis	44
Disturbance of cytoskeleton primes RIG-I-like receptors	43
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain	43
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis	42
Modelling vaccination strategies for COVID-19	41
Immunology of food aversion	41
Role of thymic stromal lymphopoietin in allergy and beyond	41
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy	40
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies	39
The role of galectins in immunity and infection	39
The role of transcription factors in shaping regulatory T cell identity	38
Transposon-derived decoy fine-tunes IFN responses	37
Understanding COVID-19-associated coagulopathy	37
Targeting ER stress sensor restores immunogenicity of chemotherapy	37
CARD8 kills CD4+ T cells in response to HIV entry	36
Linking Epstein-Barr virus infection to multiple sclerosis	36
Author Correction: The role of platelets in immune-mediated inflammatory diseases	36
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors	35
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?	35
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid	32
The diversity of CD8+ T cell dysfunction in cancer and viral infection	31
CRISPR screens for functional interrogation of immunity	30
Meningeal MAIT cells preserve brain homeostasis	30
Macrophage quality control of HSCs	29
Comparing paediatric COVID-19 with MIS-C	28
Regulation of innate-like activities of neonatal CD8+ T cells	28
Human ILC2s can act as cytolytic killers	27
Obesity-associated autoreactivity	27
Unconventional T cells shape tissue-specific lymph node responses	27
Focusing on the correct gene signatures for SLE	26
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease	26
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment	25
Signal length not strength guides T cell fate	25
Osteoblast-derived ATP maintains bone marrow plasma cells	25
STAT5A antagonizes TOX in CD8+ T cell exhaustion	24
Engaging innate immunity in HIV-1 cure strategies	24

Cardiometabolic syndrome — an emergent feature of Long COVID?	23
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses	22
A skull bone marrow niche for antitumour neutrophils in glioblastoma	22
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy	22
RORγt+ antigen-presenting cells mediate food tolerance	21
Squeeze to arm	21
Redefining our vision: an updated guide to the ocular immune system	21
Rethinking pDCs: a questionable ally in immunity?	20
DDX17 identified as inflammasome sensor for retrotransposon RNA	20
BRD4 acts as a pH sensor to tune inflammation	19
Membrane organization by tetraspanins and galectins shapes lymphocyte function	19
Opportunities and challenges for T cell-based influenza vaccines	19
Live vaccine development through targeted protein degradation	18
Obesity amplifies TH17-type pathology in atopic diseases	18
Clock genes keep intestinal ILC3s ticking	18
Sleep deprivation whips up cytokine storm	17
Fired up in the bone marrow	16
Insulin neoantigen elicits memory T cell activation in diabetes	16
Allergen immunotherapy: past, present and future	16
‘Bedside’ observations challenge aspects of the ‘epithelial barrier hypothesis’	16
Lessons from Long COVID: working with patients to design better research	15
Brief blockade of type I IFN increases CD8+ T cell memory	15
Aspirin helps T cells to stop cancer spread	15
Immune control of brain physiology	15
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis	15
Fever affects T cell fate	15
Bone marrow inflammation in haematological malignancies	14
Engineered γδ T cells show promise in bone tumours	14
Cytokines target distinct brain areas to modulate behavioural responses	13
Neutrophils release inflammation-resolving vesicles	13
Author Correction: The effect of physical exercise on anticancer immunity	13
Clonal haematopoiesis and dysregulation of the immune system	12
The role of chromatin loop extrusion in antibody diversification	12
Defining the balance between optimal immunity and immunopathology in influenza virus infection	12
Omicron entry route	11
Cerebral dysfunctions caused by sepsis during ageing	11
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria	11
Bacteria form unique biofilms to kill immune cells	11
Tick-targeted mRNA vaccine to tackle disease transmission?	11
Organoids identify a role for IL-7 in coeliac disease	10
Trogocytosis of CARs depends on transmembrane domains	10
Pain-sensing neurons calm the gut	10
A role for microglia in mediating the microbiota–gut–brain axis	9
The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?	9
Clearing the hurdles for CAR-T cell treatment	9
Daughters forget, mothers remember	9
Negative regulation of AHR essential for intestinal homeostasis	9
Beyond exhaustion: the unique characteristics of CD8+ T cell dysfunction in chronic HBV infection	9
Magnesium: essential for T cells	8
From TCR fundamental research to innovative chimeric antigen receptor design	8
Universal LIPSTIC: a new tool for decoding cellular interactions	8
T cell exhaustion: early or late in tumour progression?	8
A nuclear STING in the tail for canonical signalling	8
Dexamethasone restrains neutrophils in severe COVID-19	7
Therapeutic induction of antigen-specific immune tolerance	7
Time of day determines cancer immunotherapy response	7
Orally delivered lactate-producing bacteria limit CNS autoimmunity	7
Immunological factors linked to geographical variation in vaccine responses	7
HDAC9 association with heart disease linked to NLRP3 inflammasome activation	7
Immune ageing at single-cell resolution	7
Assessing the generation of tissue resident memory T cells by vaccines	7
Understanding vertebrate immunity through comparative immunology	6
Antitumour roles for antihistamines	6
Connection and communication between the nervous and immune systems	6
Tuning immunity through tissue mechanotransduction	6
Omicron, the great escape artist	6
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia	6
How neuroinflammation weakens muscles	6
How to respond when biomedical science and global health is under existential threat	6
Macrophage commonalities across tissues and inflammation	6
Low serotonin linked to long COVID	6
Myeloid cell-targeted therapies for solid tumours	6
Understanding NK cell heterogeneity	6
The immunology of type 1 diabetes	5
Rejuvenating an old immune system	5
Trained immunity in chronic inflammatory diseases and cancer	5
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective	5
Brief diet changes affect immunity	5
Black In Immuno: harnessing social media and digital platforms to connect the dots	5
Linking tumour angiogenesis and tumour immunity	5
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD1	5
Fasting affects monocyte lifespan and migration	5
An inter-organ neuro–immuno–endocrine circuit for glucose homeostasis	5
Reindeer antlers model skin regeneration	5
Iron and the immune system	4
Have a cake and eat it too: the importance of metaphors in research communication	4
Cancer cell metabolism and antitumour immunity	4
Considering innate immune responses in SARS-CoV-2 infection and COVID-19	4
SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact	4
The multifunctional protein HMGB1: 50 years of discovery	4
Cancer immune evasion, immunoediting and intratumour heterogeneity	4
Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation	4
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation	4
Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites	4
Short-chain fatty acids: linking diet, the microbiome and immunity	4