Nature Reviews Immunology

Papers
(The median citation count of Nature Reviews Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Regulation goes awry in the liver1327
Early life antibiotics have lasting effects on the lung epithelium1083
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis835
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses571
Decoding the human prenatal immune system with single-cell multi-omics474
Muscle spindle macrophages regulate motor coordination467
Albumin protects against deadly fungal infection448
Macrophages in embryonic development448
Shaping neutrophil morphology and function: the importance of a segmented nucleus406
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies385
Viral infection and antiviral immunity in the oral cavity380
The immunology of asthma and chronic rhinosinusitis365
The danger theory of immunity revisited354
BCG plus β-glucan trains neutrophils to beat bladder cancer353
Author Correction: Shaping neutrophil morphology and function: the importance of a segmented nucleus352
Metabolite and nutrient regulation of macrophages in obesity and metabolic disease350
Human immune organoids: a tool to study vaccine responses342
Heart failure affects innate immune memory339
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses329
Regulation of cGAS–STING signalling and its diversity of cellular outcomes308
Challenges in developing personalized neoantigen cancer vaccines290
Targeting malaria transmission289
Human T follicular regulatory cells with helper and regulatory lineage origins287
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells278
Neutrophils are dispensable for Shigella control: macrophages take centre stage270
Stressed tumours release immunosuppressive vesicles251
Novel insights into the immune response to bacterial T cell superantigens230
The distinctive immune features of long COVID225
Antiviral neutralizing antibodies: from in vitro to in vivo activity224
The NLR gene family: from discovery to present day217
Mechanistic insights from inflammasome structures209
How bile acids and the microbiota interact to shape host immunity209
A guide to adaptive immune memory203
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells201
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer198
You are what you ate: myeloid cells trained by fatty acids193
T cell–eosinophil collaboration190
Gut ILC2s remember IL-25187
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC184
Online immunology education for a global world180
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells174
Salt sensitivity includes effects on immune cell signalling and metabolism173
A guide to CAR T cell therapies: development, current status and future prospects167
Splenic stromal niches in homeostasis and immunity156
Why pigs might help us develop better vaccines and drugs against influenza virus155
The OrganiX microfluidic system to recreate the complex tumour microenvironment154
The cancer-immune dialogue in the context of stress147
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease139
Feeding IgA+ plasma cells137
JAKs drive innate-like TH9 cell activation in allergy136
Spatial resolution of host–microbiome interactions132
Negative regulation of fungal immunity by STING132
Low risk of CAR T cells going rogue131
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint130
Monocytes rule energy metabolism with an iron fist128
Bacteria in tumours promote cancer progression125
Calibrating T cell responsiveness through interactions with self123
Neutrophils make matrix to fortify barrier immunity123
Author Correction: Cancer cell metabolism and antitumour immunity122
Eosinophils shape barrier immunity during reproduction119
Olfactory immunology: the missing piece in airway and CNS defence118
The spatial and temporal activation of macrophages during fibrosis114
The immunopathogenesis of narcolepsy type 1107
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy101
Monkeypox: disease epidemiology, host immunity and clinical interventions101
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies100
The biology of TREM receptors97
Rejuvenation through checkpoint inhibitors?95
Commensal fungi support granulocyte development90
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy87
T cells target viral protein to remove senescent fibroblasts85
mRNA vaccine for treating pancreatic cancer84
Early life allergen sensitivity starts in the skin80
Spatial immunometabolic zonation in tuberculosis granulomas79
Guardians of immune privilege74
Podoplanin mediates stromal–immune crosstalk in the lymph node74
We need to keep an eye on avian influenza73
The promise of immunotherapy for central nervous system tumours73
Kupffer cells in liver homeostasis and disease: from immune sentinels to metabolic gatekeepers73
Germinal centre IL-4 enforces tissue confinement of IgE memory73
Local immune recognition of trophoblast in early human pregnancy: controversies and questions68
T cell engagers in autoimmune diseases67
Cytokine multimerization: when more is more and sometimes less67
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells65
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases65
Pollution impairs lung defences with age64
Glomerulonephritis: immunopathogenesis and immunotherapy64
Bacterial serotonin induces Treg cells in neonates62
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis61
Boosting cytotoxic T cells for immunotherapy60
Early antiviral type I interferon impairs lung metastasis58
Actin branching maintains tissue-resident mast cells56
Lung-resident memory B cells class-switch to IgE56
Asymptomatic SARS-CoV-2 linked to HLA-B*15:0155
Microbiota licenses protective CD8+ T cell responses against neonatal influenza55
Hypoxia and IL-24 drive a sterile wound healing pathway54
CODEX multiplexed tissue imaging54
Insights into immune cell–fibroblast communication in heart disease54
T cell-derived extracellular vesicles promote antitumour immunity through horizontal gene transfer52
The renaissance of oral tolerance: merging tradition and new insights51
Integrated organ immunity: a path to a universal vaccine51
Defining myeloid-derived suppressor cells51
Extrafollicular plasma cells suppress T cell priming in tumour-draining lymph nodes51
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection49
Vaginal NK cells limit epithelial barrier disruption during infection49
Turning on anti-tumour T cells via MTAP49
The autoinflammatory disease APLAID is driven by G-CSF48
Effect of prenatal stress on the developing brain48
PerturbView: scalable image-based perturbation screens in cells and tissues48
Bacteria tag tumours for CAR T cell attack48
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain46
Immunology of food aversion45
Disturbance of cytoskeleton primes RIG-I-like receptors45
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis44
NK cell mechanosensing through CD16a42
Author Correction: The immunology of long COVID42
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis42
Understanding COVID-19-associated coagulopathy40
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies40
The role of transcription factors in shaping regulatory T cell identity40
The ageing immune system as a driver of systemic ageing39
Harnessing mucosal immunity for protective vaccines38
The role of galectins in immunity and infection38
CARD8 kills CD4+ T cells in response to HIV entry37
Targeting ER stress sensor restores immunogenicity of chemotherapy37
CRISPR screen reveals regulators of age-associated CD8+ T cell dysfunction in cancer36
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid32
Protective and pathological roles of immunothrombosis in sepsis32
Transposon-derived decoy fine-tunes IFN responses31
Author Correction: The role of platelets in immune-mediated inflammatory diseases31
Metabolites as signalling molecules in the tumour immune microenvironment31
Inhibition of NR4A1 potentiates a CD8+ T cell response against active tuberculosis31
The diversity of CD8+ T cell dysfunction in cancer and viral infection30
Contextualizing TH17 cells in cancer30
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors30
Macrophage quality control of HSCs29
CRISPR screens for functional interrogation of immunity29
Human ILC2s can act as cytolytic killers28
Regulation of innate-like activities of neonatal CD8+ T cells28
Unconventional T cells shape tissue-specific lymph node responses25
Obesity-associated autoreactivity25
Focusing on the correct gene signatures for SLE24
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment23
Osteoblast-derived ATP maintains bone marrow plasma cells22
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease21
Local Treg cell loss reprogrammes systemic antitumour immunity without breaking tolerance20
Ageing tissue fibroblasts support lung inflammaging20
STAT5A antagonizes TOX in CD8+ T cell exhaustion19
Type I interferon at the crossroads of metastatic dissemination19
Immunity: from specificity to physiological integration18
Meningeal MAIT cells preserve brain homeostasis18
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses17
A skull bone marrow niche for antitumour neutrophils in glioblastoma17
How Big Data and AI are revolutionizing human immunology17
ILC2–neuron cross-talk regulates pain sensitivity and gait16
Clock genes keep intestinal ILC3s ticking16
Intracellular bacteria in cancer cells promote immunosuppression in the metastatic niche16
Live vaccine development through targeted protein degradation16
Squeeze to arm16
Insulin neoantigen elicits memory T cell activation in diabetes16
T cell competition in multi-neoantigen cancer vaccines16
Rethinking pDCs: a questionable ally in immunity?16
RORγt+ antigen-presenting cells mediate food tolerance16
Membrane organization by tetraspanins and galectins shapes lymphocyte function15
Sleep deprivation whips up cytokine storm15
Redefining our vision: an updated guide to the ocular immune system14
Allergen immunotherapy: past, present and future14
BRD4 acts as a pH sensor to tune inflammation14
Guidelines for T cell nomenclature13
Fever affects T cell fate13
Opportunities and challenges for T cell-based influenza vaccines13
Fibroblasts as regulators of lung immunity, repair and fibrosis13
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis13
Engineered γδ T cells show promise in bone tumours12
Aspirin helps T cells to stop cancer spread12
Cytokines target distinct brain areas to modulate behavioural responses11
Immune control of brain physiology11
Author Correction: The effect of physical exercise on anticancer immunity11
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria11
Hypoxia-induced epigenetic reprogramming of neutrophil progenitors11
Bacteria form unique biofilms to kill immune cells11
Clonal haematopoiesis and dysregulation of the immune system11
Tumour lactate bars B cell entry10
Bone marrow inflammation in haematological malignancies10
Proteotoxic shock is a mechanistic driver of T cell exhaustion10
Glycolytic capacity instructs tumour vasculature and response to immunotherapy10
Immune regulation by erythroid cells: how erythroid progenitor cells and mature red blood cells shape immunity10
Brief blockade of type I IFN increases CD8+ T cell memory10
Neutrophils release inflammation-resolving vesicles10
Autoimmune T cells identified in ALS10
Trogocytosis of CARs depends on transmembrane domains9
Organoids identify a role for IL-7 in coeliac disease9
Universal LIPSTIC: a new tool for decoding cellular interactions9
Defining the balance between optimal immunity and immunopathology in influenza virus infection9
Negative regulation of AHR essential for intestinal homeostasis9
Pain-sensing neurons calm the gut9
A nuclear STING in the tail for canonical signalling8
T cell exhaustion: early or late in tumour progression?8
From TCR fundamental research to innovative chimeric antigen receptor design8
Gut macrophages and Parkinson’s disease8
Daughters forget, mothers remember8
Clearing the hurdles for CAR-T cell treatment8
Abortive infection: T cells as early, antibody-independent defenders8
Beyond exhaustion: the unique characteristics of CD8+ T cell dysfunction in chronic HBV infection8
How neuroinflammation weakens muscles7
Assessing the generation of tissue resident memory T cells by vaccines7
Low serotonin linked to long COVID7
Immunological factors linked to geographical variation in vaccine responses7
Therapeutic induction of antigen-specific immune tolerance7
A role for microglia in mediating the microbiota–gut–brain axis7
How to respond when biomedical science and global health is under existential threat6
HDAC9 association with heart disease linked to NLRP3 inflammasome activation6
The immunology of vitiligo6
Understanding NK cell heterogeneity6
Orally delivered lactate-producing bacteria limit CNS autoimmunity6
A lymphatic circuit that sustains antitumour immune surveillance6
Time of day determines cancer immunotherapy response6
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia6
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD16
The immunology of type 1 diabetes6
Tuning immunity through tissue mechanotransduction5
T cell nomenclature: from subsets to modules5
Reindeer antlers model skin regeneration5
Role of the microbiota in response to and recovery from cancer therapy5
Linking tumour angiogenesis and tumour immunity5
How T cells handle lipids5
Connection and communication between the nervous and immune systems5
Brief diet changes affect immunity5
An inter-organ neuro–immuno–endocrine circuit for glucose homeostasis5
Tumour cells mimic erythroblasts to hijack iron from bone marrow macrophages5
cDC1s license CD8+ T cell-mediated neurodegeneration5
Understanding vertebrate immunity through comparative immunology5
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective5
Fasting affects monocyte lifespan and migration5
Trained immunity in chronic inflammatory diseases and cancer5
Rejuvenating an old immune system5
Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines5
Lymphatic expression of TBX1 helps to heal the heart4
Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation4
Iron and the immune system4
Can we improve immune health by restoring microbial biodiversity?4
T-regulating opioid withdrawal4
Lung-migrating helminths can enhance immunity to SARS-CoV-24
Have a cake and eat it too: the importance of metaphors in research communication4
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation4
Progress in the development of cytokine armoured CAR T cells4
Tracking the infant immune response to SARS-CoV-24
Neuron–eosinophil circuit explains stress-induced eczema flares4
Interleukin-18 armours antitumour immune effectors4
Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites4
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