Nature Reviews Immunology

Papers
(The median citation count of Nature Reviews Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)
ArticleCitations
IgA selects for fit, peace-loving fungi945
The mole rat’s secret to cancer resistance792
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies670
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis651
Heart failure affects innate immune memory531
Comparing neurological complications after COVID-19 vaccination and SARS-CoV-2 infection527
Regulation goes awry in the liver476
Lymphocytes in lockdown475
Early life antibiotics have lasting effects on the lung epithelium470
Vaccines only partially protect against Long COVID459
Viral infection and antiviral immunity in the oral cavity448
Decoding the human prenatal immune system with single-cell multi-omics376
The immunology of asthma and chronic rhinosinusitis375
Muscle spindle macrophages regulate motor coordination336
Human immune organoids: a tool to study vaccine responses329
Regulation of cGAS–STING signalling and its diversity of cellular outcomes323
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses313
The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues310
The danger theory of immunity revisited294
Challenges in developing personalized neoantigen cancer vaccines287
Stressed tumours release immunosuppressive vesicles277
Omicron alone provides limited cross-protection273
Gut commensals promote antiviral immunity via extracellular vesicles263
Targeting malaria transmission262
Lessons from vaccine-induced immune thrombotic thrombocytopenia261
Human T follicular regulatory cells with helper and regulatory lineage origins250
The distinctive immune features of long COVID243
Neutrophils are dispensable for Shigella control: macrophages take centre stage241
Encouraging vaccine uptake: lessons from behavioural science238
Novel insights into the immune response to bacterial T cell superantigens231
The NLR gene family: from discovery to present day229
A guide to adaptive immune memory223
Mechanistic insights from inflammasome structures221
How bile acids and the microbiota interact to shape host immunity219
Antiviral neutralizing antibodies: from in vitro to in vivo activity216
B cells in central nervous system disease: diversity, locations and pathophysiology215
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer213
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells210
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells208
The cancer-immune dialogue in the context of stress189
T cell–eosinophil collaboration183
You are what you ate: myeloid cells trained by fatty acids181
Bile duct tuft cells regulate immune defences177
Online immunology education for a global world171
Cross reactive T cells hold up against Omicron169
Author Correction: SARS-CoV-2 and HIV-1 – A Tale of Two Vaccines163
Author Correction: Perivascular macrophages in health and disease156
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC155
The OrganiX microfluidic system to recreate the complex tumour microenvironment150
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease149
APOL1 variants contribute to racial disparity in sepsis146
Salt sensitivity includes effects on immune cell signalling and metabolism146
Splenic stromal niches in homeostasis and immunity146
The germinal centre B cell response to SARS-CoV-2139
Mechanistic insights into Long COVID in hamsters138
Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses138
Bacteria in tumours promote cancer progression137
Feeding IgA+ plasma cells137
JAKs drive innate-like TH9 cell activation in allergy128
Negative regulation of fungal immunity by STING125
Spatial resolution of host–microbiome interactions123
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint119
Low risk of CAR T cells going rogue119
Monocytes rule energy metabolism with an iron fist118
Author Correction: Cancer cell metabolism and antitumour immunity117
Neutrophils make matrix to fortify barrier immunity116
Lessons in self-defence: inhibition of virus entry by intrinsic immunity116
Olfactory immunology: the missing piece in airway and CNS defence115
The biology of TREM receptors113
The immunopathogenesis of narcolepsy type 1111
Monkeypox: disease epidemiology, host immunity and clinical interventions109
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies108
The interplay of immunology and cachexia in infection and cancer105
A guide to antigen processing and presentation104
Foetal sex affects maternal and placental immune responses to SARS-CoV-2102
Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?102
Rejuvenation through checkpoint inhibitors?101
T cells target viral protein to remove senescent fibroblasts101
Commensal fungi support granulocyte development100
Guardians of immune privilege97
Podoplanin mediates stromal–immune crosstalk in the lymph node94
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy94
mRNA vaccine for treating pancreatic cancer93
Glomerulonephritis: immunopathogenesis and immunotherapy92
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells88
Local immune recognition of trophoblast in early human pregnancy: controversies and questions88
We need to keep an eye on avian influenza85
DNA damage and repair in age-related inflammation84
Immune-mediated inflammatory disease therapeutics: past, present and future83
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases82
Bacterial serotonin induces Treg cells in neonates79
Turning on anti-tumour T cells via MTAP79
Pollution impairs lung defences with age78
Immune epigenome75
Hypoxia and IL-24 drive a sterile wound healing pathway74
CODEX multiplexed tissue imaging73
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis71
γδ T cells sense disturbance70
Asymptomatic SARS-CoV-2 linked to HLA-B*15:0168
Boosting cytotoxic T cells for immunotherapy67
Actin branching maintains tissue-resident mast cells66
Microbiota licenses protective CD8+ T cell responses against neonatal influenza66
A billion-year-old mechanism of innate immunity uncovered65
Early antiviral type I interferon impairs lung metastasis64
Using cross-species vaccination approaches to counter emerging infectious diseases62
Lung-resident memory B cells class-switch to IgE62
Insights into immune cell–fibroblast communication in heart disease62
Integrated organ immunity: a path to a universal vaccine61
Defining myeloid-derived suppressor cells61
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases61
The renaissance of oral tolerance: merging tradition and new insights61
IL-17 and IL-17-producing cells in protection versus pathology59
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection57
First glimpses into the mechanisms of Long COVID55
B cell-derived acetylcholine curbs haematopoiesis54
Immunology of food aversion53
Effect of prenatal stress on the developing brain53
The autoinflammatory disease APLAID is driven by G-CSF52
The epigenetic ghost of infections past51
Author Correction: The immunology of long COVID51
A pan-cancer signature for dysfunctional T cells50
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis49
PerturbView: scalable image-based perturbation screens in cells and tissues49
When ‘mild’ COVID-19 is not so mild49
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies47
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain44
Bacteria tag tumours for CAR T cell attack41
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis41
Modified uridines are the key to a successful message39
Disturbance of cytoskeleton primes RIG-I-like receptors39
Inflammatory rewiring38
Modelling vaccination strategies for COVID-1937
Defining the TH17 cell lineage37
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy36
Understanding COVID-19-associated coagulopathy36
How the immune system shapes atherosclerosis: roles of innate and adaptive immunity35
TCF1 in T cell immunity: a broadened frontier34
The role of galectins in immunity and infection33
Role of thymic stromal lymphopoietin in allergy and beyond33
The role of transcription factors in shaping regulatory T cell identity32
The role of T cells in age-related diseases32
Transposon-derived decoy fine-tunes IFN responses31
Targeting ER stress sensor restores immunogenicity of chemotherapy31
Linking Epstein-Barr virus infection to multiple sclerosis31
CARD8 kills CD4+ T cells in response to HIV entry31
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors30
Author Correction: The role of platelets in immune-mediated inflammatory diseases30
The diversity of CD8+ T cell dysfunction in cancer and viral infection29
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid29
Human ILC2s can act as cytolytic killers29
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?29
Unconventional T cells shape tissue-specific lymph node responses29
CRISPR screens for functional interrogation of immunity29
Obesity-associated autoreactivity28
Focusing on the correct gene signatures for SLE27
Comparing paediatric COVID-19 with MIS-C27
Osteoblast-derived ATP maintains bone marrow plasma cells27
Regulation of innate-like activities of neonatal CD8+ T cells25
Oral mucosa atlas23
Meningeal MAIT cells preserve brain homeostasis23
Signal length not strength guides T cell fate23
Macrophage quality control of HSCs23
Detecting future coronavirus pandemics23
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease23
STAT5A antagonizes TOX in CD8+ T cell exhaustion22
Engaging innate immunity in HIV-1 cure strategies22
Inflammasome activation at the crux of severe COVID-1921
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses21
Resolving inflammation20
Cardiometabolic syndrome — an emergent feature of Long COVID?20
Obesity amplifies TH17-type pathology in atopic diseases19
Roles of natural killer cells in immunity to cancer, and applications to immunotherapy19
Squeeze to arm18
‘Bedside’ observations challenge aspects of the ‘epithelial barrier hypothesis’18
A skull bone marrow niche for antitumour neutrophils in glioblastoma18
Rethinking pDCs: a questionable ally in immunity?18
DDX17 identified as inflammasome sensor for retrotransposon RNA17
Sleep deprivation whips up cytokine storm17
Membrane organization by tetraspanins and galectins shapes lymphocyte function16
Allergen immunotherapy: past, present and future16
Opportunities and challenges for T cell-based influenza vaccines16
RORγt+ antigen-presenting cells mediate food tolerance16
Redefining our vision: an updated guide to the ocular immune system16
Neutrophils hit reverse in ageing15
Fired up in the bone marrow15
Immune control of brain physiology15
Bacteria form unique biofilms to kill immune cells14
Fever affects T cell fate14
Aspirin helps T cells to stop cancer spread14
Engineered γδ T cells show promise in bone tumours14
Neutrophils release inflammation-resolving vesicles14
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis13
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria13
Author Correction: The effect of physical exercise on anticancer immunity13
Brief blockade of type I IFN increases CD8+ T cell memory13
Cerebral dysfunctions caused by sepsis during ageing13
Omicron entry route13
Cytokines target distinct brain areas to modulate behavioural responses13
Lessons from Long COVID: working with patients to design better research13
The role of chromatin loop extrusion in antibody diversification12
Bone marrow inflammation in haematological malignancies12
Clonal haematopoiesis and dysregulation of the immune system12
Pan-sarbecovirus mAb protects from variants12
Defining the balance between optimal immunity and immunopathology in influenza virus infection12
Organoids identify a role for IL-7 in coeliac disease11
Tick-targeted mRNA vaccine to tackle disease transmission?10
T cell exhaustion: early or late in tumour progression?10
Beyond exhaustion: the unique characteristics of CD8+ T cell dysfunction in chronic HBV infection10
Trogocytosis of CARs depends on transmembrane domains10
Universal LIPSTIC: a new tool for decoding cellular interactions10
Daughters forget, mothers remember10
Pain-sensing neurons calm the gut10
A nuclear STING in the tail for canonical signalling9
Negative regulation of AHR essential for intestinal homeostasis9
Understanding COVID-19 in Africa9
The immunology of asymptomatic SARS-CoV-2 infection: what are the key questions?9
Magnesium: essential for T cells9
Immune ageing at single-cell resolution9
From TCR fundamental research to innovative chimeric antigen receptor design9
Interferon-γ: teammate or opponent in the tumour microenvironment?8
Assessing the generation of tissue resident memory T cells by vaccines8
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia7
Orally delivered lactate-producing bacteria limit CNS autoimmunity7
How neuroinflammation weakens muscles7
Immunological factors linked to geographical variation in vaccine responses7
Dexamethasone restrains neutrophils in severe COVID-197
Therapeutic induction of antigen-specific immune tolerance7
Time of day determines cancer immunotherapy response6
Understanding NK cell heterogeneity6
Low serotonin linked to long COVID6
Rejuvenating an old immune system6
Macrophage commonalities across tissues and inflammation6
Antitumour roles for antihistamines6
HDAC9 association with heart disease linked to NLRP3 inflammasome activation6
Understanding vertebrate immunity through comparative immunology6
The immunology of type 1 diabetes6
Tuning immunity through tissue mechanotransduction6
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD16
Revealing T follicular helper cells with BCL66
How to respond when biomedical science and global health is under existential threat6
Myeloid cell-targeted therapies for solid tumours6
Reindeer antlers model skin regeneration6
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective6
Omicron, the great escape artist6
An inter-organ neuro–immuno–endocrine circuit for glucose homeostasis5
IL-17A–HIF1α axis in epithelial wound repair5
SARS-CoV-2 and HIV-1 — a tale of two vaccines5
Role of the microbiota in response to and recovery from cancer therapy5
Black In Immuno: harnessing social media and digital platforms to connect the dots5
Trained immunity in chronic inflammatory diseases and cancer5
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