Nature Reviews Immunology

Papers
(The median citation count of Nature Reviews Immunology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)
ArticleCitations
Regulation goes awry in the liver1117
Heart failure affects innate immune memory1016
Early life antibiotics have lasting effects on the lung epithelium871
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis870
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses784
Vaccines only partially protect against Long COVID534
Decoding the human prenatal immune system with single-cell multi-omics436
Muscle spindle macrophages regulate motor coordination429
Albumin protects against deadly fungal infection411
Viral infection and antiviral immunity in the oral cavity376
Metabolite and nutrient regulation of macrophages in obesity and metabolic disease372
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies371
The danger theory of immunity revisited360
The immunology of asthma and chronic rhinosinusitis341
BCG plus β-glucan trains neutrophils to beat bladder cancer334
Challenges in developing personalized neoantigen cancer vaccines331
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses330
Shaping neutrophil morphology and function: the importance of a segmented nucleus321
Regulation of cGAS–STING signalling and its diversity of cellular outcomes319
Human immune organoids: a tool to study vaccine responses305
Omicron alone provides limited cross-protection300
Targeting malaria transmission298
The distinctive immune features of long COVID281
Human T follicular regulatory cells with helper and regulatory lineage origins265
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells251
Neutrophils are dispensable for Shigella control: macrophages take centre stage251
Stressed tumours release immunosuppressive vesicles246
Encouraging vaccine uptake: lessons from behavioural science243
A guide to adaptive immune memory232
Novel insights into the immune response to bacterial T cell superantigens228
The NLR gene family: from discovery to present day227
Mechanistic insights from inflammasome structures216
How bile acids and the microbiota interact to shape host immunity210
Antiviral neutralizing antibodies: from in vitro to in vivo activity195
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells195
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer193
You are what you ate: myeloid cells trained by fatty acids188
T cell–eosinophil collaboration181
Gut ILC2s remember IL-25180
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC176
Online immunology education for a global world175
The OrganiX microfluidic system to recreate the complex tumour microenvironment174
Why pigs might help us develop better vaccines and drugs against influenza virus173
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease167
Salt sensitivity includes effects on immune cell signalling and metabolism167
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells165
Splenic stromal niches in homeostasis and immunity162
The cancer-immune dialogue in the context of stress160
Feeding IgA+ plasma cells154
JAKs drive innate-like TH9 cell activation in allergy151
Negative regulation of fungal immunity by STING144
Mechanistic insights into Long COVID in hamsters139
Spatial resolution of host–microbiome interactions131
Low risk of CAR T cells going rogue123
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint123
Bacteria in tumours promote cancer progression120
Monocytes rule energy metabolism with an iron fist120
Author Correction: Cancer cell metabolism and antitumour immunity119
Olfactory immunology: the missing piece in airway and CNS defence118
Neutrophils make matrix to fortify barrier immunity117
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy115
Calibrating T cell responsiveness through interactions with self115
Eosinophils shape barrier immunity during reproduction113
The immunopathogenesis of narcolepsy type 1112
Monkeypox: disease epidemiology, host immunity and clinical interventions112
The spatial and temporal activation of macrophages during fibrosis106
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies103
The biology of TREM receptors103
Rejuvenation through checkpoint inhibitors?98
Commensal fungi support granulocyte development92
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy91
T cells target viral protein to remove senescent fibroblasts88
mRNA vaccine for treating pancreatic cancer85
Cytokine multimerization: when more is more and sometimes less78
Kupffer cells in liver homeostasis and disease: from immune sentinels to metabolic gatekeepers77
Early life allergen sensitivity starts in the skin76
Spatial immunometabolic zonation in tuberculosis granulomas74
Podoplanin mediates stromal–immune crosstalk in the lymph node73
Guardians of immune privilege71
Germinal centre IL-4 enforces tissue confinement of IgE memory69
The promise of immunotherapy for central nervous system tumours68
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells67
Glomerulonephritis: immunopathogenesis and immunotherapy66
DNA damage and repair in age-related inflammation64
We need to keep an eye on avian influenza62
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases60
Local immune recognition of trophoblast in early human pregnancy: controversies and questions58
Pollution impairs lung defences with age58
Bacterial serotonin induces Treg cells in neonates57
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis56
Boosting cytotoxic T cells for immunotherapy56
Early antiviral type I interferon impairs lung metastasis55
Lung-resident memory B cells class-switch to IgE54
Microbiota licenses protective CD8+ T cell responses against neonatal influenza52
Actin branching maintains tissue-resident mast cells52
Asymptomatic SARS-CoV-2 linked to HLA-B*15:0151
Hypoxia and IL-24 drive a sterile wound healing pathway51
Insights into immune cell–fibroblast communication in heart disease50
Turning on anti-tumour T cells via MTAP50
The renaissance of oral tolerance: merging tradition and new insights49
CODEX multiplexed tissue imaging49
Defining myeloid-derived suppressor cells48
T cell-derived extracellular vesicles promote antitumour immunity through horizontal gene transfer48
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection47
Integrated organ immunity: a path to a universal vaccine47
Effect of prenatal stress on the developing brain47
IL-17 and IL-17-producing cells in protection versus pathology47
The autoinflammatory disease APLAID is driven by G-CSF46
When ‘mild’ COVID-19 is not so mild45
PerturbView: scalable image-based perturbation screens in cells and tissues42
Bacteria tag tumours for CAR T cell attack42
Disturbance of cytoskeleton primes RIG-I-like receptors41
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain41
Immunology of food aversion40
NK cell mechanosensing through CD16a39
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies37
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis37
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis36
Role of thymic stromal lymphopoietin in allergy and beyond35
Harnessing mucosal immunity for protective vaccines35
The role of transcription factors in shaping regulatory T cell identity34
The ageing immune system as a driver of systemic ageing34
Author Correction: The immunology of long COVID34
Understanding COVID-19-associated coagulopathy34
The role of galectins in immunity and infection33
CARD8 kills CD4+ T cells in response to HIV entry32
Targeting ER stress sensor restores immunogenicity of chemotherapy32
Transposon-derived decoy fine-tunes IFN responses31
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid30
Author Correction: The role of platelets in immune-mediated inflammatory diseases30
CRISPR screen reveals regulators of age-associated CD8+ T cell dysfunction in cancer29
Contextualizing TH17 cells in cancer29
Metabolites as signalling molecules in the tumour immune microenvironment28
Inhibition of NR4A1 potentiates a CD8+ T cell response against active tuberculosis28
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors28
CRISPR screens for functional interrogation of immunity27
The diversity of CD8+ T cell dysfunction in cancer and viral infection27
Macrophage quality control of HSCs26
Unconventional T cells shape tissue-specific lymph node responses25
Regulation of innate-like activities of neonatal CD8+ T cells25
Obesity-associated autoreactivity25
Human ILC2s can act as cytolytic killers25
Focusing on the correct gene signatures for SLE23
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment23
Osteoblast-derived ATP maintains bone marrow plasma cells22
Type I interferon at the crossroads of metastatic dissemination21
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease20
Local Treg cell loss reprogrammes systemic antitumour immunity without breaking tolerance19
Meningeal MAIT cells preserve brain homeostasis18
The impact of pre-existing cross-reactive immunity on SARS-CoV-2 infection and vaccine responses18
Ageing tissue fibroblasts support lung inflammaging18
STAT5A antagonizes TOX in CD8+ T cell exhaustion18
RORγt+ antigen-presenting cells mediate food tolerance17
A skull bone marrow niche for antitumour neutrophils in glioblastoma17
Intracellular bacteria in cancer cells promote immunosuppression in the metastatic niche16
Insulin neoantigen elicits memory T cell activation in diabetes16
Squeeze to arm16
BRD4 acts as a pH sensor to tune inflammation16
ILC2–neuron cross-talk regulates pain sensitivity and gait16
Rethinking pDCs: a questionable ally in immunity?16
Live vaccine development through targeted protein degradation16
Clock genes keep intestinal ILC3s ticking16
Opportunities and challenges for T cell-based influenza vaccines15
Membrane organization by tetraspanins and galectins shapes lymphocyte function15
Fibroblasts as regulators of lung immunity, repair and fibrosis15
Redefining our vision: an updated guide to the ocular immune system15
T cell competition in multi-neoantigen cancer vaccines15
Allergen immunotherapy: past, present and future14
Guidelines for T cell nomenclature14
Resident tissue macrophages maintain intraocular pressure by regulating extracellular matrix homeostasis13
Fever affects T cell fate13
Aspirin helps T cells to stop cancer spread13
Sleep deprivation whips up cytokine storm13
Immune regulation by erythroid cells: how erythroid progenitor cells and mature red blood cells shape immunity12
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria12
Defining the balance between optimal immunity and immunopathology in influenza virus infection12
Autoimmune T cells identified in ALS11
Cytokines target distinct brain areas to modulate behavioural responses11
Author Correction: The effect of physical exercise on anticancer immunity11
Engineered γδ T cells show promise in bone tumours11
Hypoxia-induced epigenetic reprogramming of neutrophil progenitors11
Tumour lactate bars B cell entry10
Proteotoxic shock is a mechanistic driver of T cell exhaustion10
Bacteria form unique biofilms to kill immune cells10
Brief blockade of type I IFN increases CD8+ T cell memory10
Neutrophils release inflammation-resolving vesicles10
Organoids identify a role for IL-7 in coeliac disease9
Clonal haematopoiesis and dysregulation of the immune system9
Immune control of brain physiology9
Pain-sensing neurons calm the gut9
Bone marrow inflammation in haematological malignancies9
Gut macrophages and Parkinson’s disease8
Negative regulation of AHR essential for intestinal homeostasis8
Abortive infection: T cells as early, antibody-independent defenders8
Universal LIPSTIC: a new tool for decoding cellular interactions8
Daughters forget, mothers remember8
A nuclear STING in the tail for canonical signalling8
Trogocytosis of CARs depends on transmembrane domains8
Clearing the hurdles for CAR-T cell treatment8
Beyond exhaustion: the unique characteristics of CD8+ T cell dysfunction in chronic HBV infection8
Orally delivered lactate-producing bacteria limit CNS autoimmunity7
T cell exhaustion: early or late in tumour progression?7
From TCR fundamental research to innovative chimeric antigen receptor design7
Immunological factors linked to geographical variation in vaccine responses7
A role for microglia in mediating the microbiota–gut–brain axis7
Therapeutic induction of antigen-specific immune tolerance7
Assessing the generation of tissue resident memory T cells by vaccines7
Low serotonin linked to long COVID6
TGFβ control of immune responses in cancer: a holistic immuno-oncology perspective6
Clonal haematopoiesis-associated, age-related motor deficits caused by monocyte-derived microglia6
How neuroinflammation weakens muscles6
HDAC9 association with heart disease linked to NLRP3 inflammasome activation6
Time of day determines cancer immunotherapy response6
Understanding NK cell heterogeneity6
How to respond when biomedical science and global health is under existential threat6
T cell nomenclature: from subsets to modules6
Understanding vertebrate immunity through comparative immunology6
Insights from a 30-year journey: function, regulation and therapeutic modulation of PD15
An inter-organ neuro–immuno–endocrine circuit for glucose homeostasis5
IL-17A–HIF1α axis in epithelial wound repair5
Connection and communication between the nervous and immune systems5
Myeloid cell-targeted therapies for solid tumours5
Brief diet changes affect immunity5
How T cells handle lipids5
Fasting affects monocyte lifespan and migration5
The immunology of type 1 diabetes5
The immunology of vitiligo5
Reindeer antlers model skin regeneration5
Tumour cells mimic erythroblasts to hijack iron from bone marrow macrophages5
Tuning immunity through tissue mechanotransduction5
Tracking the infant immune response to SARS-CoV-24
Trained immunity in chronic inflammatory diseases and cancer4
Rejuvenating an old immune system4
Considering innate immune responses in SARS-CoV-2 infection and COVID-194
Progress in the development of cytokine armoured CAR T cells4
Cancer immune evasion, immunoediting and intratumour heterogeneity4
Lung-migrating helminths can enhance immunity to SARS-CoV-24
T-regulating opioid withdrawal4
Linking tumour angiogenesis and tumour immunity4
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation4
Neuron–eosinophil circuit explains stress-induced eczema flares4
Iron and the immune system4
Cancer cell metabolism and antitumour immunity4
Lymphatic expression of TBX1 helps to heal the heart4
Role of the microbiota in response to and recovery from cancer therapy4
Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines4
Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation4
Cooperation of ILC2s and TH2 cells in the expulsion of intestinal helminth parasites4
Can we improve immune health by restoring microbial biodiversity?4
Have a cake and eat it too: the importance of metaphors in research communication4
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