OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Immunology is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Regulation goes awry in the liver	1117
Heart failure affects innate immune memory	1016
Early life antibiotics have lasting effects on the lung epithelium	871
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis	870
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses	784
Vaccines only partially protect against Long COVID	534
Decoding the human prenatal immune system with single-cell multi-omics	436
Muscle spindle macrophages regulate motor coordination	429
Albumin protects against deadly fungal infection	411
Viral infection and antiviral immunity in the oral cavity	376
Metabolite and nutrient regulation of macrophages in obesity and metabolic disease	372
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	371
The danger theory of immunity revisited	360
The immunology of asthma and chronic rhinosinusitis	341
BCG plus β-glucan trains neutrophils to beat bladder cancer	334
Challenges in developing personalized neoantigen cancer vaccines	331
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses	330
Shaping neutrophil morphology and function: the importance of a segmented nucleus	321
Regulation of cGAS–STING signalling and its diversity of cellular outcomes	319
Human immune organoids: a tool to study vaccine responses	305
Omicron alone provides limited cross-protection	300
Targeting malaria transmission	298
The distinctive immune features of long COVID	281
Human T follicular regulatory cells with helper and regulatory lineage origins	265
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells	251

Neutrophils are dispensable for Shigella control: macrophages take centre stage	251
Stressed tumours release immunosuppressive vesicles	246
Encouraging vaccine uptake: lessons from behavioural science	243
A guide to adaptive immune memory	232
Novel insights into the immune response to bacterial T cell superantigens	228
The NLR gene family: from discovery to present day	227
Mechanistic insights from inflammasome structures	216
How bile acids and the microbiota interact to shape host immunity	210
Antiviral neutralizing antibodies: from in vitro to in vivo activity	195
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells	195
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer	193
You are what you ate: myeloid cells trained by fatty acids	188
T cell–eosinophil collaboration	181
Gut ILC2s remember IL-25	180
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC	176
Online immunology education for a global world	175
The OrganiX microfluidic system to recreate the complex tumour microenvironment	174
Why pigs might help us develop better vaccines and drugs against influenza virus	173
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease	167
Salt sensitivity includes effects on immune cell signalling and metabolism	167
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells	165
Splenic stromal niches in homeostasis and immunity	162
The cancer-immune dialogue in the context of stress	160
Feeding IgA+ plasma cells	154
JAKs drive innate-like TH9 cell activation in allergy	151
Negative regulation of fungal immunity by STING	144
Mechanistic insights into Long COVID in hamsters	139
Spatial resolution of host–microbiome interactions	131
Low risk of CAR T cells going rogue	123
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint	123
Bacteria in tumours promote cancer progression	120
Monocytes rule energy metabolism with an iron fist	120
Author Correction: Cancer cell metabolism and antitumour immunity	119
Olfactory immunology: the missing piece in airway and CNS defence	118
Neutrophils make matrix to fortify barrier immunity	117
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy	115
Calibrating T cell responsiveness through interactions with self	115
Eosinophils shape barrier immunity during reproduction	113
The immunopathogenesis of narcolepsy type 1	112
Monkeypox: disease epidemiology, host immunity and clinical interventions	112
The spatial and temporal activation of macrophages during fibrosis	106
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	103
The biology of TREM receptors	103
Rejuvenation through checkpoint inhibitors?	98
Commensal fungi support granulocyte development	92
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy	91
T cells target viral protein to remove senescent fibroblasts	88
mRNA vaccine for treating pancreatic cancer	85
Cytokine multimerization: when more is more and sometimes less	78
Kupffer cells in liver homeostasis and disease: from immune sentinels to metabolic gatekeepers	77

Early life allergen sensitivity starts in the skin	76
Spatial immunometabolic zonation in tuberculosis granulomas	74
Podoplanin mediates stromal–immune crosstalk in the lymph node	73
Guardians of immune privilege	71
Germinal centre IL-4 enforces tissue confinement of IgE memory	69
The promise of immunotherapy for central nervous system tumours	68
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells	67
Glomerulonephritis: immunopathogenesis and immunotherapy	66
DNA damage and repair in age-related inflammation	64
We need to keep an eye on avian influenza	62
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases	60
Local immune recognition of trophoblast in early human pregnancy: controversies and questions	58
Pollution impairs lung defences with age	58
Bacterial serotonin induces Treg cells in neonates	57
Boosting cytotoxic T cells for immunotherapy	56
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis	56
Early antiviral type I interferon impairs lung metastasis	55
Lung-resident memory B cells class-switch to IgE	54
Microbiota licenses protective CD8+ T cell responses against neonatal influenza	52
Actin branching maintains tissue-resident mast cells	52
Hypoxia and IL-24 drive a sterile wound healing pathway	51
Asymptomatic SARS-CoV-2 linked to HLA-B*15:01	51
Turning on anti-tumour T cells via MTAP	50
Insights into immune cell–fibroblast communication in heart disease	50
The renaissance of oral tolerance: merging tradition and new insights	49
CODEX multiplexed tissue imaging	49
T cell-derived extracellular vesicles promote antitumour immunity through horizontal gene transfer	48
Defining myeloid-derived suppressor cells	48
Integrated organ immunity: a path to a universal vaccine	47
Effect of prenatal stress on the developing brain	47
IL-17 and IL-17-producing cells in protection versus pathology	47
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection	47
The autoinflammatory disease APLAID is driven by G-CSF	46
When ‘mild’ COVID-19 is not so mild	45
Bacteria tag tumours for CAR T cell attack	42
PerturbView: scalable image-based perturbation screens in cells and tissues	42
Disturbance of cytoskeleton primes RIG-I-like receptors	41
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain	41
Immunology of food aversion	40
NK cell mechanosensing through CD16a	39
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies	37
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis	37
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis	36
Harnessing mucosal immunity for protective vaccines	35
Role of thymic stromal lymphopoietin in allergy and beyond	35
The ageing immune system as a driver of systemic ageing	34
Author Correction: The immunology of long COVID	34
Understanding COVID-19-associated coagulopathy	34
The role of transcription factors in shaping regulatory T cell identity	34
The role of galectins in immunity and infection	33
CARD8 kills CD4+ T cells in response to HIV entry	32
Targeting ER stress sensor restores immunogenicity of chemotherapy	32
Transposon-derived decoy fine-tunes IFN responses	31
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid	30
Author Correction: The role of platelets in immune-mediated inflammatory diseases	30
Contextualizing TH17 cells in cancer	29
CRISPR screen reveals regulators of age-associated CD8+ T cell dysfunction in cancer	29
Inhibition of NR4A1 potentiates a CD8+ T cell response against active tuberculosis	28
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors	28
Metabolites as signalling molecules in the tumour immune microenvironment	28
The diversity of CD8+ T cell dysfunction in cancer and viral infection	27
CRISPR screens for functional interrogation of immunity	27
Macrophage quality control of HSCs	26
Regulation of innate-like activities of neonatal CD8+ T cells	25
Obesity-associated autoreactivity	25
Human ILC2s can act as cytolytic killers	25
Unconventional T cells shape tissue-specific lymph node responses	25
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment	23
Focusing on the correct gene signatures for SLE	23