OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Immunology is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Regulation goes awry in the liver	1327
Early life antibiotics have lasting effects on the lung epithelium	1083
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis	835
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses	571
Decoding the human prenatal immune system with single-cell multi-omics	474
Muscle spindle macrophages regulate motor coordination	467
Macrophages in embryonic development	448
Albumin protects against deadly fungal infection	448
Shaping neutrophil morphology and function: the importance of a segmented nucleus	406
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	385
Viral infection and antiviral immunity in the oral cavity	380
The immunology of asthma and chronic rhinosinusitis	365
The danger theory of immunity revisited	354
BCG plus β-glucan trains neutrophils to beat bladder cancer	353
Author Correction: Shaping neutrophil morphology and function: the importance of a segmented nucleus	352
Metabolite and nutrient regulation of macrophages in obesity and metabolic disease	350
Human immune organoids: a tool to study vaccine responses	342
Heart failure affects innate immune memory	339
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses	329
Regulation of cGAS–STING signalling and its diversity of cellular outcomes	308
Challenges in developing personalized neoantigen cancer vaccines	290
Targeting malaria transmission	289
Human T follicular regulatory cells with helper and regulatory lineage origins	287
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells	278
Neutrophils are dispensable for Shigella control: macrophages take centre stage	270

Stressed tumours release immunosuppressive vesicles	251
Novel insights into the immune response to bacterial T cell superantigens	230
The distinctive immune features of long COVID	225
Antiviral neutralizing antibodies: from in vitro to in vivo activity	224
The NLR gene family: from discovery to present day	217
How bile acids and the microbiota interact to shape host immunity	209
Mechanistic insights from inflammasome structures	209
A guide to adaptive immune memory	203
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells	201
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer	198
You are what you ate: myeloid cells trained by fatty acids	193
T cell–eosinophil collaboration	190
Gut ILC2s remember IL-25	187
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC	184
Online immunology education for a global world	180
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells	174
Salt sensitivity includes effects on immune cell signalling and metabolism	173
A guide to CAR T cell therapies: development, current status and future prospects	167
Splenic stromal niches in homeostasis and immunity	156
Why pigs might help us develop better vaccines and drugs against influenza virus	155
The OrganiX microfluidic system to recreate the complex tumour microenvironment	154
The cancer-immune dialogue in the context of stress	147
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease	139
Feeding IgA+ plasma cells	137
JAKs drive innate-like TH9 cell activation in allergy	136
Negative regulation of fungal immunity by STING	132
Spatial resolution of host–microbiome interactions	132
Low risk of CAR T cells going rogue	131
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint	130
Monocytes rule energy metabolism with an iron fist	128
Bacteria in tumours promote cancer progression	125
Neutrophils make matrix to fortify barrier immunity	123
Calibrating T cell responsiveness through interactions with self	123
Author Correction: Cancer cell metabolism and antitumour immunity	122
Eosinophils shape barrier immunity during reproduction	119
Olfactory immunology: the missing piece in airway and CNS defence	118
The spatial and temporal activation of macrophages during fibrosis	114
The immunopathogenesis of narcolepsy type 1	107
Microenvironmental regulation of solid tumour resistance to CAR T cell therapy	101
Monkeypox: disease epidemiology, host immunity and clinical interventions	101
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	100
The biology of TREM receptors	97
Rejuvenation through checkpoint inhibitors?	95
Commensal fungi support granulocyte development	90
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy	87
T cells target viral protein to remove senescent fibroblasts	85
mRNA vaccine for treating pancreatic cancer	84
Early life allergen sensitivity starts in the skin	80
Spatial immunometabolic zonation in tuberculosis granulomas	79
Podoplanin mediates stromal–immune crosstalk in the lymph node	74

Guardians of immune privilege	74
Kupffer cells in liver homeostasis and disease: from immune sentinels to metabolic gatekeepers	73
Germinal centre IL-4 enforces tissue confinement of IgE memory	73
We need to keep an eye on avian influenza	73
The promise of immunotherapy for central nervous system tumours	73
Local immune recognition of trophoblast in early human pregnancy: controversies and questions	68
Cytokine multimerization: when more is more and sometimes less	67
T cell engagers in autoimmune diseases	67
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells	65
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases	65
Glomerulonephritis: immunopathogenesis and immunotherapy	64
Pollution impairs lung defences with age	64
Bacterial serotonin induces Treg cells in neonates	62
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis	61
Boosting cytotoxic T cells for immunotherapy	60
Early antiviral type I interferon impairs lung metastasis	58
Actin branching maintains tissue-resident mast cells	56
Lung-resident memory B cells class-switch to IgE	56
Asymptomatic SARS-CoV-2 linked to HLA-B*15:01	55
Microbiota licenses protective CD8+ T cell responses against neonatal influenza	55
Hypoxia and IL-24 drive a sterile wound healing pathway	54
CODEX multiplexed tissue imaging	54
Insights into immune cell–fibroblast communication in heart disease	54
T cell-derived extracellular vesicles promote antitumour immunity through horizontal gene transfer	52
The renaissance of oral tolerance: merging tradition and new insights	51
Integrated organ immunity: a path to a universal vaccine	51
Defining myeloid-derived suppressor cells	51
Extrafollicular plasma cells suppress T cell priming in tumour-draining lymph nodes	51
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection	49
Vaginal NK cells limit epithelial barrier disruption during infection	49
Turning on anti-tumour T cells via MTAP	49
The autoinflammatory disease APLAID is driven by G-CSF	48
Effect of prenatal stress on the developing brain	48
PerturbView: scalable image-based perturbation screens in cells and tissues	48
Bacteria tag tumours for CAR T cell attack	48
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain	46
Immunology of food aversion	45
Disturbance of cytoskeleton primes RIG-I-like receptors	45
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis	44
NK cell mechanosensing through CD16a	42
Author Correction: The immunology of long COVID	42
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis	42
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies	40
The role of transcription factors in shaping regulatory T cell identity	40
Understanding COVID-19-associated coagulopathy	40
The ageing immune system as a driver of systemic ageing	39
The role of galectins in immunity and infection	38
Harnessing mucosal immunity for protective vaccines	38
CARD8 kills CD4+ T cells in response to HIV entry	37
Targeting ER stress sensor restores immunogenicity of chemotherapy	37
CRISPR screen reveals regulators of age-associated CD8+ T cell dysfunction in cancer	36
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid	32
Protective and pathological roles of immunothrombosis in sepsis	32
Transposon-derived decoy fine-tunes IFN responses	31
Author Correction: The role of platelets in immune-mediated inflammatory diseases	31
Metabolites as signalling molecules in the tumour immune microenvironment	31
Inhibition of NR4A1 potentiates a CD8+ T cell response against active tuberculosis	31
The diversity of CD8+ T cell dysfunction in cancer and viral infection	30
Contextualizing TH17 cells in cancer	30
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors	30
Macrophage quality control of HSCs	29
CRISPR screens for functional interrogation of immunity	29
Human ILC2s can act as cytolytic killers	28
Regulation of innate-like activities of neonatal CD8+ T cells	28
Unconventional T cells shape tissue-specific lymph node responses	25
Obesity-associated autoreactivity	25
Focusing on the correct gene signatures for SLE	24
Fetal Treg cell reprogramming links maternal immunity to neurodevelopment	23
Osteoblast-derived ATP maintains bone marrow plasma cells	22