OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Immunology is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Regulation goes awry in the liver	907
Heart failure affects innate immune memory	795
Comparing neurological complications after COVID-19 vaccination and SARS-CoV-2 infection	646
Author Correction: Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	634
Early life antibiotics have lasting effects on the lung epithelium	587
BCG plus β-glucan trains neutrophils to beat bladder cancer	553
The danger theory of immunity revisited	545
The immunology of asthma and chronic rhinosinusitis	436
Natural killer cells that target autoimmune cells linked with protection against multiple sclerosis	396
Viral infection and antiviral immunity in the oral cavity	376
Decoding the human prenatal immune system with single-cell multi-omics	371
Human immune organoids: a tool to study vaccine responses	326
Exercise induces metabolic changes in the gut microbiota that enhance anti-tumour T cell responses	326
Vaccines only partially protect against Long COVID	310
Challenges in developing personalized neoantigen cancer vaccines	301
Muscle spindle macrophages regulate motor coordination	299
Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses	298
Regulation of cGAS–STING signalling and its diversity of cellular outcomes	275
Stressed tumours release immunosuppressive vesicles	272
Omicron alone provides limited cross-protection	267
Gut commensals promote antiviral immunity via extracellular vesicles	266
Targeting malaria transmission	259
Lessons from vaccine-induced immune thrombotic thrombocytopenia	257
Novel insights into the immune response to bacterial T cell superantigens	255
The distinctive immune features of long COVID	254

Human T follicular regulatory cells with helper and regulatory lineage origins	252
Fatty liver disease induced by maternal obesity is driven by metabolic rewiring of Kupffer cells	244
Neutrophils are dispensable for Shigella control: macrophages take centre stage	241
Antiviral neutralizing antibodies: from in vitro to in vivo activity	223
The NLR gene family: from discovery to present day	218
How bile acids and the microbiota interact to shape host immunity	216
Encouraging vaccine uptake: lessons from behavioural science	208
Mechanistic insights from inflammasome structures	198
A guide to adaptive immune memory	198
B cells in central nervous system disease: diversity, locations and pathophysiology	195
Mapping the developmental trajectory and recruitment of memory-phenotype Ly49+CD8+ T cells	188
Salt sensitivity includes effects on immune cell signalling and metabolism	188
Blood neutrophil subset predicts the success of immune checkpoint inhibitors in cancer	188
You are what you ate: myeloid cells trained by fatty acids	173
Bile duct tuft cells regulate immune defences	163
T cell–eosinophil collaboration	162
Adaptive meets innate: CD8+ T cells kill MHC-I-negative tumour cells	162
Gut ILC2s remember IL-25	161
Author Correction: SARS-CoV-2 and HIV-1 – A Tale of Two Vaccines	160
The kiss a cell can’t forget: tracking cell–cell interactions with uLIPSTIC	152
Online immunology education for a global world	152
APOL1 variants contribute to racial disparity in sepsis	151
The OrganiX microfluidic system to recreate the complex tumour microenvironment	149
Cross reactive T cells hold up against Omicron	144
The cancer-immune dialogue in the context of stress	143
Splenic stromal niches in homeostasis and immunity	142
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease	136
The germinal centre B cell response to SARS-CoV-2	135
JAKs drive innate-like TH9 cell activation in allergy	131
Bacteria in tumours promote cancer progression	131
Feeding IgA+ plasma cells	131
Negative regulation of fungal immunity by STING	130
Mechanistic insights into Long COVID in hamsters	129
Defective viral genomes can protect against SARS-CoV-2 variants and other respiratory viruses	128
Spatial resolution of host–microbiome interactions	128
Low risk of CAR T cells going rogue	127
An ILC3-intrinsic, CTLA4-dependent intestinal checkpoint	123
Monocytes rule energy metabolism with an iron fist	123
Neutrophils make matrix to fortify barrier immunity	120
The immunopathogenesis of narcolepsy type 1	117
Author Correction: Cancer cell metabolism and antitumour immunity	113
The spatial and temporal activation of macrophages during fibrosis	113
The biology of TREM receptors	111
Lessons in self-defence: inhibition of virus entry by intrinsic immunity	111
Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies	111
Olfactory immunology: the missing piece in airway and CNS defence	111
The interplay of immunology and cachexia in infection and cancer	104
Monkeypox: disease epidemiology, host immunity and clinical interventions	103
A guide to antigen processing and presentation	100
Rejuvenation through checkpoint inhibitors?	100

T cells target viral protein to remove senescent fibroblasts	99
Foetal sex affects maternal and placental immune responses to SARS-CoV-2	94
Commensal fungi support granulocyte development	92
Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?	92
Publisher Correction: Immunological studies in trans-individuals undergoing gender affirming hormone therapy	91
Podoplanin mediates stromal–immune crosstalk in the lymph node	90
Guardians of immune privilege	90
The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases	89
DNA damage and repair in age-related inflammation	85
We need to keep an eye on avian influenza	85
mRNA vaccine for treating pancreatic cancer	83
Local immune recognition of trophoblast in early human pregnancy: controversies and questions	80
MR1 antigen presentation to MAIT cells and other MR1-restricted T cells	80
Spatial immunometabolic zonation in tuberculosis granulomas	78
Glomerulonephritis: immunopathogenesis and immunotherapy	78
Pollution impairs lung defences with age	77
Bacterial serotonin induces Treg cells in neonates	75
γδ T cells sense disturbance	74
Neutralizing autoantibodies against type 1 interferons identified in West Nile virus encephalitis	74
Boosting cytotoxic T cells for immunotherapy	73
Microbiota licenses protective CD8+ T cell responses against neonatal influenza	72
Actin branching maintains tissue-resident mast cells	69
Insights into immune cell–fibroblast communication in heart disease	68
Asymptomatic SARS-CoV-2 linked to HLA-B*15:01	67
Hypoxia and IL-24 drive a sterile wound healing pathway	64
Early antiviral type I interferon impairs lung metastasis	63
Integrated organ immunity: a path to a universal vaccine	62
Lung-resident memory B cells class-switch to IgE	62
Beyond neutralization: Fc-dependent antibody effector functions in SARS-CoV-2 infection	60
The renaissance of oral tolerance: merging tradition and new insights	59
Turning on anti-tumour T cells via MTAP	58
Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases	57
Defining myeloid-derived suppressor cells	56
CODEX multiplexed tissue imaging	56
IL-17 and IL-17-producing cells in protection versus pathology	55
First glimpses into the mechanisms of Long COVID	53
Effect of prenatal stress on the developing brain	52
The autoinflammatory disease APLAID is driven by G-CSF	50
Author Correction: The immunology of long COVID	49
A pan-cancer signature for dysfunctional T cells	48
Mitochondria in monocyte-derived cells promote tissue damage in multiple sclerosis	47
When ‘mild’ COVID-19 is not so mild	46
B cell-derived acetylcholine curbs haematopoiesis	44
PerturbView: scalable image-based perturbation screens in cells and tissues	44
Bacteria tag tumours for CAR T cell attack	44
Boosting glymphatic drainage via adrenergic receptor inhibition protects the injured brain	43
Disturbance of cytoskeleton primes RIG-I-like receptors	43
NMDAR-directed CAAR T cells show promise for autoimmune encephalitis	42
Immunology of food aversion	41
Role of thymic stromal lymphopoietin in allergy and beyond	41
Modelling vaccination strategies for COVID-19	41
SARS-CoV-2 infection and COVID-19 vaccination in pregnancy	40
The role of galectins in immunity and infection	39
Trogocytosis challenges the cellular specificity of lineage markers and monoclonal antibodies	39
The role of transcription factors in shaping regulatory T cell identity	38
Understanding COVID-19-associated coagulopathy	37
Targeting ER stress sensor restores immunogenicity of chemotherapy	37
Transposon-derived decoy fine-tunes IFN responses	37
Linking Epstein-Barr virus infection to multiple sclerosis	36
Author Correction: The role of platelets in immune-mediated inflammatory diseases	36
CARD8 kills CD4+ T cells in response to HIV entry	36
Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast?	35
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors	35
Macrophages bordering the brain parenchyma regulate the flow of cerebrospinal fluid	32
The diversity of CD8+ T cell dysfunction in cancer and viral infection	31
CRISPR screens for functional interrogation of immunity	30
Meningeal MAIT cells preserve brain homeostasis	30
Macrophage quality control of HSCs	29
Comparing paediatric COVID-19 with MIS-C	28
Regulation of innate-like activities of neonatal CD8+ T cells	28
Unconventional T cells shape tissue-specific lymph node responses	27
Human ILC2s can act as cytolytic killers	27
Obesity-associated autoreactivity	27
Publisher Correction: Inflammasome components as new therapeutic targets in inflammatory disease	26
Focusing on the correct gene signatures for SLE	26