OOIR: Observatory of International Research

Papers

(The H4-Index of Aging Cell is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Issue Information	197
Associations of combined accelerated biological aging and genetic susceptibility with incidence of heart failure in a population‐based cohort study	139
Effects of Aging on Glucose and Lipid Metabolism in Mice	131
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice	123
Circadian regulation in aging: Implications for spaceflight and life on earth	121
Cooperative effects of SIRT1 and SIRT2 on APP acetylation	115
Featured Cover	104
Age‐related changes in metabolites in young donor livers and old recipient sera after liver transplantation from young to old rats	104
Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment	102
Inflammatory and immune markers in HIV‐infected older adults on long‐term antiretroviral therapy: Persistent elevation of sCD14 and of proinflammatory effector memory T cells	94
Additional Cover	89
Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic ma	88
Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia	79
Expression of mitochondrial oxidative stress response genes in muscle is associated with mitochondrial respiration, physical performance, and muscle mass in the Study of Muscle, Mobility, and Aging	78
SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation	77
A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo	73
Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in LG/J Mice	71
Correlates of life course physical activity in participants of the Baltimore longitudinal study of aging	70
Aging influences the cardiac macrophage phenotype and function during steady state and during inflammation	69
Long‐term Tai Chi practice in older adults is associated with “younger” functional abilities	66
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells	65
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy	65
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain	62
Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation	62
Epigenetic clock and methylation studies in elephants	61

Telomere Position Effect‐Over Long Distances Acts as a Genome‐Wide Epigenetic Regulator Through a Common Alu Element	59
Cisd2 slows down liver aging and attenuates age‐related metabolic dysfunction in male mice	59
Advanced age and female sex protect cerebral arteries from mitochondrial depolarization and apoptosis during acute oxidative stress	58
Role of autophagy in aging: The good, the bad, and the ugly	58
Age‐dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging	57
Alpha‐ketoglutarate ameliorates age‐related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF‐κB signaling	56
Nanocarriers for natural polyphenol senotherapeutics	56
Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training	54
Issue Information	53
Dysregulated nicotinamide adenine dinucleotide metabolome in patients hospitalized with COVID‐19	53
Enhanced NRF2 expression mitigates the decline in neural stem cell function during aging	53
Targeting TGF‐β signaling, oxidative stress, and cellular senescence rescues osteoporosis in gerodermia osteodysplastica	53
S‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects	53
Anatomical Society Research Studentships 2023/24	52
	52
Cockayne syndrome B protein is implicated in transcription and associated chromatin dynamics in homeostatic and genotoxic conditions	51
Association between prescription drugs and all‐cause mortality risk in the UK population	51
Hippocampal rejuvenation by a single intracerebral injection of one‐carbon metabolites in C57BL6 old wild‐type mice	51
Corrigendum to: Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction	49
Corrigendum to: Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice	47
Cellular senescence contributes to spontaneous repair of the rat meniscus	47
Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects	46
The role of cardiac resident macrophage in cardiac aging	46
Skeletal muscle DNA methylation: Effects of exercise and HIV	46
Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells	46
4‐phenylbutyric acid—Identity crisis; can it act as a translation inhibitor?	46
Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis	46
Reduced bone morphogenic protein signaling along the gut–neuron axis by heat shock factor promotes longevity	46