OOIR: Observatory of International Research

Papers

(The H4-Index of Aging Cell is 45. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury	181
Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex‐specific pattern	127
Lifetime age‐related changes in clinical laboratory results, aging clocks and mortality predictors in 2412 Golden Retrievers	118
seRNA PAM controls skeletal muscle satellite cell proliferation and aging through trans regulation of Timp2 expression synergistically with Ddx5	117
Circular RNA Telomerase Reverses Endothelial Senescence in Progeria	113
Effects of the VIVIFRAIL Exercise Protocol on Circulatory and Intracellular Peripheral Mediators Bridging Mitochondrial Dynamics and Inflammation in Robust and Frail Older People	113
Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment	108
Knockdown of RUVBL2 improves hnRNPA2/B1‐stress granules dynamics to inhibit perioperative neurocognitive disorders in aged mild cognitive impairment rats	98
Metabolomic characterization of unintentional weight loss among community‐dwelling older Black and White men and women	96
The Ercc1^−/Δ mouse model of XFE progeroid syndrome undergoes accelerated retinal degeneration	94
Accumulation of senescent cells in the adrenal gland induces hypersecretion of corticosterone via IL1β secretion	92
Non‐enzymatic function of WRN RECQL helicase regulates removal of topoisomerase‐I‐DNA covalent complexes and triggers NF‐κB signaling in cancer	89
Genetic context drives age‐related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits	85
Epigenetic clock and methylation studies in elephants	80
Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic ma	75
Additional Cover	75
Asparagine prevents intestinal stem cell aging via the autophagy‐lysosomal pathway	74
	71
Featured Cover	64
Issue Information	64
CAV1 Exacerbates Renal Tubular Epithelial Cell Senescence by Suppressing CaMKK2/AMPK‐Mediated Autophagy	63
	63
Issue Information	63
Additional Cover	60
Featured Cover	59

	58
Sensitivity of the S1 neuronal calcium network to insulin and Bay‐K 8644 in vivo: Relationship to gait, motivation, and aging processes	57
Additional Cover	56
Proteomes of primary skin fibroblasts from healthy individuals reveal altered cell responses across the life span	55
microRNA‐425 loss mediates amyloid plaque microenvironment heterogeneity and promotes neurodegenerative pathologies	55
Oculopharyngeal muscular dystrophy mutations link the RNA‐binding protein HNRNPQ to autophagosome biogenesis	55
Acyl coenzyme A binding protein (ACBP): An aging‐ and disease‐relevant “autophagy checkpoint”	55
Single‐worm quantitative proteomics reveals aging heterogeneity in isogenic Caenorhabditis elegans	54
Sexual dimorphism in the peripheral metabolic homeostasis and behavior in the TgF344‐AD rat model of Alzheimer's disease	53
Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia	53
Biomarkers of cellular senescence and risk of death in humans	53
	53
CCR4‐NOT subunit CCF‐1/CNOT7 promotes transcriptional activation to multiple stress responses in Caenorhabditis elegans	52
Müller Glia maintain their regenerative potential despite degeneration in the aged zebrafish retina	50
Cpt1a silencing in AgRP neurons improves cognitive and physical capacity and promotes healthy aging in male mice	50
Announcement	48
Issue Information	47
Issue Information	47
Featured Cover	47
Methylation entropy landscape of Chinese long‐lived individuals reveals lower epigenetic noise related to human healthy aging	45
Centenarian hippocampus displays high levels of astrocytic metallothioneins	45