OOIR: Observatory of International Research

Papers

(The H4-Index of Aging Cell is 50. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype	190
Effects of Aging on Glucose and Lipid Metabolism in Mice	133
Lactate Secretion by Monocytes as a Determinant of Innate Immune Cell Fitness in Healthy Elderly	125
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy	124
Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial	118
S‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects	114
Alpha‐ketoglutarate ameliorates age‐related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF‐κB signaling	113
Long‐term Tai Chi practice in older adults is associated with “younger” functional abilities	105
Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation	104
Correlates of life course physical activity in participants of the Baltimore longitudinal study of aging	88
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice	87
Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment	86
Additional Cover	84
Issue Information	81
Featured Cover	79
Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic ma	79
Aging Adipose‐Derived Mesenchymal Stem Cells, Cultured on a Native Young Extracellular Matrix, Are Protected From Senescence and Apoptosis Along With Increased Expression of HLA‐DR	75
Expression of mitochondrial oxidative stress response genes in muscle is associated with mitochondrial respiration, physical performance, and muscle mass in the Study of Muscle, Mobility, and Aging	73
Telomere Position Effect‐Over Long Distances Acts as a Genome‐Wide Epigenetic Regulator Through a Common Alu Element	72
Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia	72
Advanced age and female sex protect cerebral arteries from mitochondrial depolarization and apoptosis during acute oxidative stress	69
Associations of combined accelerated biological aging and genetic susceptibility with incidence of heart failure in a population‐based cohort study	69
Nanocarriers for natural polyphenol senotherapeutics	68
Cooperative effects of SIRT1 and SIRT2 on APP acetylation	67
Circadian regulation in aging: Implications for spaceflight and life on earth	67

SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation	67
Cisd2 slows down liver aging and attenuates age‐related metabolic dysfunction in male mice	67
Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in LG/J Mice	66
Age‐dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging	66
A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo	65
Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training	63
Inflammatory and immune markers in HIV‐infected older adults on long‐term antiretroviral therapy: Persistent elevation of sCD14 and of proinflammatory effector memory T cells	61
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells	60
Role of autophagy in aging: The good, the bad, and the ugly	60
Corrigendum to: Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice	59
Age‐dependent aneuploidy in mammalian oocytes instigated at the second meiotic division	59
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain	59
Corrigendum to: Wnt/β‐catenin/RAS signaling mediates age‐related renal fibrosis and is associated with mitochondrial dysfunction	58
Cockayne syndrome B protein is implicated in transcription and associated chromatin dynamics in homeostatic and genotoxic conditions	57
CALB1 and RPL23 Are Essential for Maintaining Oocyte Quality and Function During Aging	54
Heterozygous OT‐I mice reveal that antigen‐specific CD8⁺ T cells shift from apoptotic to necrotic killers in the elderly	54
Correction to “Multiple Outcomes of the Germline p16^INK4a Mutation Affecting Senescence and Immunity in Human Skin”	53
The role of cardiac resident macrophage in cardiac aging	53
Trends of genetic contributions on epigenetic clocks and related methylation sites with aging: A population‐based adult twin study	52
Issue Information	52
Reduction of DNA Topoisomerase Top2 Reprograms the Epigenetic Landscape and Extends Health and Life Span Across Species	51
Alterations of lipid‐mediated mitophagy result in aging‐dependent sensorimotor defects	51
Cellular senescence contributes to spontaneous repair of the rat meniscus	50
Anatomical Society Research Studentships 2023/24	50
Ecological Realism Accelerates Epigenetic Aging in Mice	50
DNA methylation and chromatin accessibility predict age in the domestic dog	50