OOIR: Observatory of International Research

Papers

(The H4-Index of Aging Cell is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Featured Cover	215
Advanced age and female sex protect cerebral arteries from mitochondrial depolarization and apoptosis during acute oxidative stress	153
Longitudinal analysis of physical function in older adults: The effects of physical inactivity and exercise training	149
Telomere Position Effect‐Over Long Distances Acts as a Genome‐Wide Epigenetic Regulator Through a Common Alu Element	138
Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double‐Blind Randomized Crossover Placebo‐Controlled Trial	122
Cooperative effects of SIRT1 and SIRT2 on APP acetylation	111
Alpha‐ketoglutarate ameliorates age‐related and surgery induced temporomandibular joint osteoarthritis via regulating IKK/NF‐κB signaling	109
Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells	108
Associations of combined accelerated biological aging and genetic susceptibility with incidence of heart failure in a population‐based cohort study	104
Aging influences the cardiac macrophage phenotype and function during steady state and during inflammation	99
Effects of Aging on Glucose and Lipid Metabolism in Mice	95
Circadian regulation in aging: Implications for spaceflight and life on earth	90
Age‐dependent changes in the gut microbiota and serum metabolome correlate with renal function and human aging	80
Long‐term Tai Chi practice in older adults is associated with “younger” functional abilities	79
Additional Cover	78
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice	77
Compromised CD8+ T cell immunity in the aged brain increases severity of neurotropic coronavirus infection and postinfectious cognitive impairment	75
Chronic TNF exposure induces glucocorticoid‐like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia	72
Expression of mitochondrial oxidative stress response genes in muscle is associated with mitochondrial respiration, physical performance, and muscle mass in the Study of Muscle, Mobility, and Aging	71
SCARF2 is a target for chronic obstructive pulmonary disease: Evidence from multi‐omics research and cohort validation	68
Blood–brain barrier dysfunction promotes astrocyte senescence through albumin‐induced TGFβ signaling activation	66
Telomere length and micronuclei trajectories in APP/PS1 mouse model of Alzheimer's disease: Correlating with cognitive impairment and brain amyloidosis in a sexually dimorphic ma	66
Senescence Cell Induction Methods Display Diverse Metabolic Reprogramming and Reveal an Underpinning Serine/Taurine Reductive Metabolic Phenotype	66
Issue Information	66
Inflammatory and immune markers in HIV‐infected older adults on long‐term antiretroviral therapy: Persistent elevation of sCD14 and of proinflammatory effector memory T cells	65

Cisd2 slows down liver aging and attenuates age‐related metabolic dysfunction in male mice	63
Oral Citrate Supplementation Mitigates Age‐Associated Pathologic Intervertebral Disc Calcification in LG/J Mice	63
Role of autophagy in aging: The good, the bad, and the ugly	62
Growth differentiation factor 11 accelerates liver senescence through the inhibition of autophagy	61
Accelerated cerebromicrovascular senescence contributes to cognitive decline in a mouse model of paclitaxel (Taxol)‐induced chemobrain	61
S‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects	61
A p21‐GFP zebrafish model of senescence for rapid testing of senolytics in vivo	59
Correlates of life course physical activity in participants of the Baltimore longitudinal study of aging	59
Nanocarriers for natural polyphenol senotherapeutics	58
	57
Fibroblast growth factor 10 ameliorates neurodegeneration in mouse and cellular models of Alzheimer's disease via reducing tau hyperphosphorylation and neuronal apoptosis	57
4‐phenylbutyric acid—Identity crisis; can it act as a translation inhibitor?	56
Trends of genetic contributions on epigenetic clocks and related methylation sites with aging: A population‐based adult twin study	55
Association between prescription drugs and all‐cause mortality risk in the UK population	55
Hippocampal rejuvenation by a single intracerebral injection of one‐carbon metabolites in C57BL6 old wild‐type mice	55
Ecological Realism Accelerates Epigenetic Aging in Mice	52
Anatomical Society Research Studentships 2023/24	52
Age‐dependent aneuploidy in mammalian oocytes instigated at the second meiotic division	51
Corrigendum to: Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice	50
Young donor hematopoietic stem cells revitalize aged or damaged bone marrow niche by transdifferentiating into functional niche cells	50
Correction to “Multiple Outcomes of the Germline p16^INK4a Mutation Affecting Senescence and Immunity in Human Skin”	50
Lipoteichoic acid restrains macrophage senescence via β‐catenin/FOXO1/REDD1 pathway in age‐related osteoporosis	49
The role of cardiac resident macrophage in cardiac aging	49
Chemically induced senescence in human stem cell‐derived neurons promotes phenotypic presentation of neurodegeneration	48
Deciphering the role of immune cell composition in epigenetic age acceleration: Insights from cell‐type deconvolution applied to human blood epigenetic clocks	48
Skeletal muscle DNA methylation: Effects of exercise and HIV	48
3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex	48