Molecular Cancer

Papers
(The TQCC of Molecular Cancer is 46. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Correction to: The function and mechanisms of action of circular RNAs in Urologic Cancer1926
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments1002
Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy954
ERK mediates interferon gamma-induced melanoma cell death881
Retraction Note: Epigenetic modification of ferroptosis by non-coding RNAs in cancer drug resistance741
The puppet master in the breast cancer “microecological community”: spatial and metabolic regulation of macrophage heterogeneity721
SOS1: tracking the evolving path from promising to actionable therapeutic target in RAS-dependent cancers621
Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma583
KRAS and MYC synergistic inhibition: a powerful strategy targeting KRAS-mutant cancers507
Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatment479
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers450
Spatial and functional dissection of cancer-associated fibroblasts-mediated immune modulation in H. pylori-associated gastric cancer405
The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers397
Immunotherapies in rare cancers371
LMTK3 regulation of EV biogenesis and cargo sorting promotes tumour growth by reducing monocyte infiltration and driving pro-tumourigenic macrophage polarisation in breast cancer360
TGF-β signaling promotes cervical cancer metastasis via CDR1as358
Mutation-specific dynamics of dedifferentiation trajectories and tumor–stromal interactions in thyroid cancer324
BRD9-p53-E2F1 circuit orchestrates cell growth and DNA damage repair in gastric cancer307
The CD47/TSP-1 axis: a promising avenue for ovarian cancer treatment and biomarker research303
The miR-23a/27a/24 − 2 cluster drives immune evasion and resistance to PD-1/PD-L1 blockade in non-small cell lung cancer302
Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells295
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression280
Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery280
Systemic immunosuppression limits NK cell therapy efficacy in pancreatic cancer268
Tumor microenvironment dynamics in gastric cancer pathogenesis and therapeutic resistance266
circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis260
Advances in RNA-based cancer therapeutics: pre-clinical and clinical implications259
Exosomal circSIPA1L3-mediated intercellular communication contributes to glucose metabolic reprogramming and progression of triple negative breast cancer248
Chaperone-mediated autophagy modulates Snail protein stability: implications for breast cancer metastasis247
Neoadjuvant immunotherapy in squamous cell carcinoma of the head and neck: current evidence and future perspectives243
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway242
LINC02159 promotes non-small cell lung cancer progression via ALYREF/YAP1 signaling241
Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers241
Development and validation of a small extracellular vesicle-derived RNA signature for early diagnosis of lung adenocarcinoma and prognosis in advanced stages236
Biomarker-empowered precision navigation of CAR-T cell therapy231
AcTor, a novel mTOR stimulator, potentiates ixazomib for the treatment of acute myeloid leukemia230
Correction: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis225
Correction: YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment223
Nuclear receptors as novel regulators that modulate cancer radiosensitivity and normal tissue radiotoxicity221
Increased plasma concentrations of acyl-coenzyme A binding protein (ACBP) predict future lung cancer development in smokers at risk of cardiovascular disease219
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state213
Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation212
Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells212
Context-dependent effect of glucocorticoid receptor activity shapes ovarian cancer cell plasticity and therapy response206
Tumor cell-intrinsic MELK enhanced CCL2-dependent immunosuppression to exacerbate hepatocarcinogenesis and confer resistance of HCC to radiotherapy202
LncRNA PVT1 in human cancers: genomic complexity, isoforms, functional elements, mechanism of action, subcellular localization and possible role as a therapeutic target202
Effects of RNA methylation on Tumor angiogenesis and cancer progression201
Bidirectional role of neutrophils in tumor development193
Emerging roles of tRNA-derived fragments in cancer192
Efferocytosis: the art of cellular clearance and novel perspectives in disease therapy191
NK cells are never alone: crosstalk and communication in tumour microenvironments191
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments190
Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes189
Gold nanoparticles and gold nanorods in the landscape of cancer therapy185
Biofilm formation by the host microbiota: a protective shield against immunity and its implication in cancer183
Biomolecular phase separation in tumorigenesis: from aberrant condensates to therapeutic vulnerabilities182
Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer179
Nanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing179
Nanomedicine in Cancer Therapeutics: Current Perspectives from Bench to Bedside178
Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells174
LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling174
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance173
Tumor-associated macrophages: untapped molecular targets to improve T cell-based immunotherapy173
The application of organoids in treatment decision-making for digestive system cancers: progress and challenges172
Metabolic reprogramming and molecular crosstalk at the cancer–endothelial interface in ovarian carcinoma170
Modeling pediatric low-grade glioma heterogeneity using human forebrain organoids168
Deconstructing cancer in 3D: models, mechanisms, and personalized solutions164
Correction: The circACTN4 interacts with FUBP1 to promote tumorigenesis and progression of breast cancer by regulating the expression of proto-oncogene MYC164
Targeting cholesterol-driven immunometabolism in cancer: from molecular circuits to clinical translation161
Correction: Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT1158
Correction: Circular RNA ACVR2A suppresses bladder cancer cells proliferation and metastasis through miR-626/EYA4 axis158
Retraction Note: Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis158
Correction: CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling157
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer157
Radionuclide‑drug conjugates in lung cancer: advances in precision therapy and clinical translation154
lncRNAs: the unexpected link between protein synthesis and cancer adaptation147
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy145
Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies144
Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma144
Circular RNA circCLASP2 promotes nasopharyngeal carcinoma progression through binding to DHX9 to enhance PCMT1 translation138
Dissecting small cell carcinoma of the esophagus ecosystem by single-cell transcriptomic analysis138
DLL3-guided therapies in small-cell lung cancer: from antibody-drug conjugate to precision immunotherapy and radioimmunotherapy132
m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma131
Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition131
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11129
Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression126
Context-dependent impact of type I interferon signaling in cancer124
Biologically targeted dual adaptive and innate nano-Immunotherapy for clear cell renal cell carcinoma treatment124
Redifferentiation-enabled TSHRCART cells overcome antigen loss in aggressive thyroid cancers124
A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression124
EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?123
Neuroscience of cancer: unraveling the complex interplay between the nervous system, the tumor and the tumor immune microenvironment122
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors122
Activation-induced cytidine deaminase causes recurrent splicing mutations in diffuse large B-cell lymphoma121
Molecular mechanisms of tumor resistance to radiotherapy121
Size matters: integrating tumour volume and immune activation signatures predicts immunotherapy response119
Correction: Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy116
Precision immunotherapy for head and neck cancer: therapeutic combinations, biomarker strategies, and translational challenges115
Breast cancer immunotherapy: mechanisms of immune evasion, biomarkers, and emerging therapeutic strategies115
Correction: MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer114
Harnessing the MYB-dependent TAL1 5’super-enhancer for targeted therapy in T-ALL113
Retraction Note: Reduced expression of AMPK-β1 during tumor progression enhances the oncogenic capacity of advanced ovarian cancer113
Cancer neuroscience in head and neck: interactions, modulation, and therapeutic strategies111
Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma111
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients109
Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age109
Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy108
CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling107
PD1/PD-L1 blockade in clear cell renal cell carcinoma: mechanistic insights, clinical efficacy, and future perspectives107
BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors106
Therapy-induced senescence is a transient drug resistance mechanism in breast cancer106
Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond105
Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA104
Co-transcriptional R-loops-mediated epigenetic regulation drives growth retardation and docetaxel chemosensitivity enhancement in advanced prostate cancer104
Spatial multi-omics analyses of the tumor immune microenvironment: advances and novel therapeutic avenues104
Metabolic plasticity underlies ferroptosis resistance driven by mutant p53 in pancreatic ductal adenocarcinoma104
Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response104
An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer103
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway103
Metabolic checkpoints in immune cell reprogramming: rewiring immunometabolism for cancer therapy99
Inhibition of 6-phosphogluconate dehydrogenase suppresses esophageal squamous cell carcinoma growth and enhances the anti-tumor effects of metformin via the AMPK/mTOR pathway96
A positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasis96
Targeting metastasis in paediatric bone sarcomas96
Retraction Note: Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer95
N-glycosylation of PD-L1 modulates the efficacy of immune checkpoint blockades targeting PD-L1 and PD-195
Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges95
A high proportion of germline variants in pediatric chronic myeloid leukemia94
Spatiotemporal dynamics of radioresistance: decoding macrophage-driven radioprotective niches through temporal-spatial reprogramming94
BIRC2 blockade facilitates immunotherapy of hepatocellular carcinoma94
Targeting MYC in T-Cell lymphoma via epigenetic modulation with a small-molecule inhibitor93
Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway91
Adjuvant recombinant human endostatin combined with toripalimab (anti-PD-1) in locally advanced melanoma: an exploratory phase 2 clinical trial incorporating single-cell RNA/TCR/BCR sequencing90
CircKIAA1617 promotes stemness via USP14/PGRMC1-mediated autophagy and lipid metabolism reprogramming in ER-positive breast cancer89
Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer88
A non-complement role for C1R rewires integrin and death-receptor signaling to drive renal cancer metastasis88
Multi-omics profiling uncovers immune-molecular clusters with distinct chemo-immunotherapeutic vulnerabilities in a mouse model of triple-negative breast cancer87
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine87
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination86
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling86
Role of a novel circRNA-CGNL1 in regulating pancreatic cancer progression via NUDT4–HDAC4–RUNX2–GAMT-mediated apoptosis86
Spatiotemporal metabolomic approaches to the cancer-immunity panorama: a methodological perspective84
Biological and pharmacological roles of m6A modifications in cancer drug resistance84
Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis84
A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better84
Integrating single cell- and spatial- resolved transcriptomics unravels the inter-tumor heterogeneity and immunosuppressive landscape in HBV- and Clonorchis sinensis-associated hepatocellular carcinom83
Identification of HSP90B1 in pan-cancer hallmarks to aid development of a potential therapeutic target83
Beyond the mouse: 3R-guided alternative animal models transforming cancer research82
EIF4A3/circPTGR1/miR-4725-5p positive- feedback loop promotes colorectal cancer progression via FAK/AKT signaling pathway82
Inflammation in cancer: therapeutic opportunities from new insights81
Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells80
Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT180
Anti irradiation nanoparticles shelter immune organ from radio-damage via preventing the IKK/IκB/NF-κB activation80
Exosomal miR-4745-5p/3911 from N2-polarized tumor-associated neutrophils promotes gastric cancer metastasis by regulating SLIT280
Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment79
Epithelial-to-mesenchymal transition (EMT) and cancer metastasis: the status quo of methods and experimental models 202579
Correction: Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance78
Pangaea Oncology, Dexeus University Hospital: bridging preclinical and clinical research78
Correction: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression78
CBFA2T2: a novel H3K27 reader regulating metabolism and tumor growth78
Retraction Note to: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis77
Correction: YC-1 enhances the anti-tumor activity of sorafenib through inhibition of signal transducer and activator of transcription 3 (STAT3) in hepatocellular carcinoma77
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development76
Shifting landscapes of gender equity in oncology journals: a decade of authorship trends76
SELP+ TEC:CD8+ T cell crosstalk associates with improved radiotherapy efficacy in cervical cancer76
[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma76
Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway76
Immune dynamics shaping pre-metastatic and metastatic niches in liver metastases: from molecular mechanisms to therapeutic strategies75
Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells75
Exploring molecular and cellular mechanisms of Pre-Metastatic niche in renal cell carcinoma75
Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors74
Correction: Proteogenomic characterization of molecular and cellular targets for treatment‑resistant subtypes in locally advanced cervical cancers73
Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency73
Spatially-resolved subtype progression reveals metabolic vulnerabilities in pancreatic ductal adenocarcinoma73
Microbiome-targeted nanoplatforms and engineering approaches in breast cancer therapy72
Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy72
A comprehensive overview of ovarian cancer stem cells: correlation with high recurrence rate, underlying mechanisms, and therapeutic opportunities72
CircHERC1 promotes non-small cell lung cancer cell progression by sequestering FOXO1 in the cytoplasm and regulating the miR-142-3p-HMGB1 axis72
YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment72
Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma71
Overcoming resistance to anti-PD-L1 immunotherapy: mechanisms, combination strategies, and future directions71
Correction: Cell‑autonomous IL6ST activation suppresses prostate cancer development via STAT3/ARF/p53‑driven senescence and confers an immune‑active tumor microenvironment71
Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis71
Cancer stem cell-driven drug resistance in colorectal carcinoma: molecular aspects and therapeutic potentials71
Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment70
Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy70
Exploiting innate immunity for cancer immunotherapy69
Next-generation CAR-T cells design: leveraging tumor features for enhanced efficacy69
Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network69
Correction: The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin69
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma68
Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers68
CircRNA aptamer targets IGF2BP2 to overcome acquired BETi resistance68
A prospective multi-cohort study identifies and validates a 5-gene peripheral blood signature predictive of immunotherapy response in non-small cell lung cancer68
Retraction Note: Quercetin-induced miR-200b-3p regulates the mode of self-renewing divisions in pancreatic cancer68
Targeting m7G-enriched circKDM1A prevents colorectal cancer progression67
The application of organoids in investigating immune evasion in the microenvironment of gastric cancer and screening novel drug candidates66
Combined proteomics and CRISPR‒Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo65
Circulating cell-free DNA methylation patterns as non-invasive biomarkers to monitor colorectal cancer treatment efficacy without referencing primary site mutation profiles64
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations64
Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translation64
Expression of mTOR in normal and pathological conditions63
c-Rel drives pancreatic cancer metastasis through fibronectin-integrin signaling-induced isolation stress resistance and EMT63
Hijacking of the nervous system in cancer: mechanism and therapeutic targets63
STING-Activating nanoplatforms for image-guided sonodynamic cancer therapy63
Multifunctional chitosan–doxorubicin nanocarriers: advancing targeted breast cancer chemotherapy63
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia62
Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T62
Extracellular vesicles in tumor immunity: mechanisms and novel insights62
Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells62
Lactate: elucidating its indispensable role in human health62
Mapping cancer biology in space: applications and perspectives on spatial omics for oncology62
Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches61
The University of Kansas Cancer Center (KUCC), an NCI designated comprehensive cancer center61
Correction: circCYP24A1 facilitates esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB-induced CCL5 secretion61
Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations60
Mechanisms and cross-talk of regulated cell death and their epigenetic modifications in tumor progression60
A plasma proteomic signature of cancer-related sarcopenia implicates the IGFBP axis in muscle dysfunction60
Commentary on “Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells”60
Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma60
Non-coding RNAs as master regulators of ferroptosis in cancer: mechanisms and clinical implications60
Correction: CMTM6 overexpression confers trastuzumab resistance in HER2‑positive breast cancer60
Correction: Circular RNA F-circSR derived from SLC34A2-ROS1 fusion gene promotes cell migration in non-small cell lung cancer59
A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer59
Correction: ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH59
Downregulation of Sod2 increases atypical flat lesions and dysplasia to advance pancreatic ductal adenocarcinoma59
​​The immune microenvironment of pathogen-associated cancers and current clinical therapeutics58
The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy58
Targeting HASPIN-mediated H3T3 phosphorylation disrupts an epigenetic-kinesin axis to suppress colorectal cancer mitotic progression58
Correction: Long noncoding RNA TLNC1 promotes the growth and metastasis of liver cancer via inhibition of p53 signaling58
Traditional Chinese medicine in the treatment of breast Cancer58
Metabolic reprogramming in cancer: signaling pathways and therapeutic targets58
Evolution of direct RAS inhibitors: from undruggable target to clinical breakthroughs57
Lipid reprogramming and ferroptosis crosstalk in clear cell renal cell carcinoma: metabolic vulnerabilities and therapeutic targeting57
Correction: Comprehensive review of CRISPR‑based gene editing: mechanisms, challenges, and applications in cancer therapy57
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy57
circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX457
CAR T cells: engineered immune cells to treat brain cancers and beyond57
Clinical application of liquid biopsy in colorectal cancer: detection, prediction, and treatment monitoring56
PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy56
Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer55
HPGD induces ferroptosis and autophagy to suppress esophageal squamous cell carcinoma through the LXA4–ERK1/2–U2AF2–TFRC axis54
Spatial proteomics reveals four-stage molecular evolution in cancer immunotherapy-related gastritis54
The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer54
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity54
Deciphering the role of LGALS2: insights into tertiary lymphoid structure-associated dendritic cell activation and immunotherapeutic potential in breast cancer patients54
Transfer RNA-derived small RNAs in tumor microenvironment53
Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop53
Retraction Note: N6-methyladenosine induced mir-143-3p promotes the brain metastasis of lung cancer via regulation of VASH152
NSCLC brain metastases exhibit reduced HLA-I antigen presentation machinery and immune evasion independent of IFNγ signaling defects52
Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug52
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