Molecular Cancer

Article	Citations
Chaperone-mediated autophagy modulates Snail protein stability: implications for breast cancer metastasis	1474
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma	956
Immunotherapies in rare cancers	930
The CD47/TSP-1 axis: a promising avenue for ovarian cancer treatment and biomarker research	886
E3 ubiquitin ligase MAGI3 degrades c-Myc and acts as a predictor for chemotherapy response in colorectal cancer	664
TGF-β signaling promotes cervical cancer metastasis via CDR1as	611
Correction: m6A demethylase ALKBH5 inhibits tumor growth and metastasis by reducing YTHDFs-mediated YAP expression and inhibiting miR-107/LATS2–mediated YAP activity in NSCLC	575
Intercellular TIMP-1-CD63 signaling directs the evolution of immune escape and metastasis in KRAS-mutated pancreatic cancer cells	558
Proteogenomic characterization of molecular and cellular targets for treatment-resistant subtypes in locally advanced cervical cancers	543
LMTK3 regulation of EV biogenesis and cargo sorting promotes tumour growth by reducing monocyte infiltration and driving pro-tumourigenic macrophage polarisation in breast cancer	527
Correction to: The function and mechanisms of action of circular RNAs in Urologic Cancer	519
Polyamine and EIF5A hypusination downstream of c-Myc confers targeted therapy resistance in BRAF mutant melanoma	498
JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression	461
Exosomal circSIPA1L3-mediated intercellular communication contributes to glucose metabolic reprogramming and progression of triple negative breast cancer	451
STAT3/LKB1 controls metastatic prostate cancer by regulating mTORC1/CREB pathway	393
Engineered multifunctional nanoparticles for enhanced radiation therapy: three-in-one approach for cancer treatment	364
The miR-23a/27a/24 − 2 cluster drives immune evasion and resistance to PD-1/PD-L1 blockade in non-small cell lung cancer	317
Genome-wide CRISPR screening identifies tyrosylprotein sulfotransferase-2 as a target for augmenting anti-PD1 efficacy	302
Using single-cell sequencing technology to detect circulating tumor cells in solid tumors	286
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments	285
ERK mediates interferon gamma-induced melanoma cell death	284
CRISPR based therapeutics: a new paradigm in cancer precision medicine	274
Traditional Chinese medicine for the treatment of cancers of hepatobiliary system: from clinical evidence to drug discovery	271
LINC02159 promotes non-small cell lung cancer progression via ALYREF/YAP1 signaling	262
The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p/CARM1 axis	260

The epigenetic regulatory mechanism of PIWI/piRNAs in human cancers	249
Advances in immunology and immunotherapy for mesenchymal gastrointestinal cancers	241
circNOX4 activates an inflammatory fibroblast niche to promote tumor growth and metastasis in NSCLC via FAP/IL-6 axis	226
EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3	216
Nanomedicine in Cancer Therapeutics: Current Perspectives from Bench to Bedside	213
Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation	208
Correction: Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis	207
Correction: YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment	207
Correction to: The lncRNA UCA1 promotes proliferation, migration, immune escape and inhibits apoptosis in gastric cancer by sponging anti-tumor miRNAs	201
Nuclear receptors as novel regulators that modulate cancer radiosensitivity and normal tissue radiotoxicity	200
A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state	199
Biofilm formation by the host microbiota: a protective shield against immunity and its implication in cancer	195
Nanotechnology-leveraged CRISPR/Cas systems: icebreaking in trace cancer-related nucleic acids biosensing	187
KMT2C methyltransferase domain regulated INK4A expression suppresses prostate cancer metastasis	184
Letter to the Editor: An ultra-sensitive assay using cell-free DNA fragmentomics for multi-cancer early detection	173
Myofibroblast-derived extracellular vesicles facilitate cancer stemness of hepatocellular carcinoma via transferring ITGA5 to tumor cells	173
PIK3CA mutations-mediated downregulation of circLHFPL2 inhibits colorectal cancer progression via upregulating PTEN	173
Tumor cell-intrinsic MELK enhanced CCL2-dependent immunosuppression to exacerbate hepatocarcinogenesis and confer resistance of HCC to radiotherapy	171
Effects of RNA methylation on Tumor angiogenesis and cancer progression	169
Emerging roles of tRNA-derived fragments in cancer	167
Bidirectional role of neutrophils in tumor development	158
Molecular mechanisms and therapeutic significance of Tryptophan Metabolism and signaling in cancer	156
LINC00115 promotes chemoresistant breast cancer stem-like cell stemness and metastasis through SETDB1/PLK3/HIF1α signaling	154
NK cells are never alone: crosstalk and communication in tumour microenvironments	151
Gold nanoparticles and gold nanorods in the landscape of cancer therapy	150
Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes	147
Extracellular matrix remodeling in tumor progression and immune escape: from mechanisms to treatments	146
Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer	145
A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer	143
Insights into N6-methyladenosine and programmed cell death in cancer	143
Targeting HNRNPU to overcome cisplatin resistance in bladder cancer	142
The phospholipid transporter PITPNC1 links KRAS to MYC to prevent autophagy in lung and pancreatic cancer	141
DLL3-guided therapies in small-cell lung cancer: from antibody-drug conjugate to precision immunotherapy and radioimmunotherapy	140
Correction: CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling	139
Retraction Note: Tetrathiomolybdate inhibits head and neck cancer metastasis by decreasing tumor cell motility, invasiveness and by promoting tumor cell anoikis	138
Dissecting small cell carcinoma of the esophagus ecosystem by single-cell transcriptomic analysis	135
Crosstalk between autophagy and microbiota in cancer progression	131
Loss of TACC2 impairs chemokine CCL3 and CCL4 expression and reduces response to anti-PD-1 therapy in soft tissue sarcoma	131
Acidosis-mediated increase in IFN-γ-induced PD-L1 expression on cancer cells as an immune escape mechanism in solid tumors	130
An ADAR1-dependent RNA editing event in the cyclin-dependent kinase CDK13 promotes thyroid cancer hallmarks	130
Single-cell RNA sequencing reveals markers of disease progression in primary cutaneous T-cell lymphoma	125
CircAKT3 promotes prostate cancer proliferation and metastasis by enhancing the binding of RPS27A and RPL11	125
lncRNAs: the unexpected link between protein synthesis and cancer adaptation	123
Correction: Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT1	121
Biologically targeted dual adaptive and innate nano-Immunotherapy for clear cell renal cell carcinoma treatment	121
Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells	117
Deubiquitination of CDC6 by OTUD6A promotes tumour progression and chemoresistance	117
Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies	117
Comprehensive characterization of the prostate tumor microenvironment identifies CXCR4/CXCL12 crosstalk as a novel antiangiogenic therapeutic target in prostate cancer	115
Neuroscience of cancer: unraveling the complex interplay between the nervous system, the tumor and the tumor immune microenvironment	114

EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?	113
Circular RNA circCLASP2 promotes nasopharyngeal carcinoma progression through binding to DHX9 to enhance PCMT1 translation	113
Liquid biopsy in lung cancer: significance in diagnostics, prediction, and treatment monitoring	112
m6A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma	112
Engineering the next-generation of CAR T-cells with CRISPR-Cas9 gene editing	112
A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression	111
Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression	111
Enhancing therapeutic anti-cancer responses by combining immune checkpoint and tyrosine kinase inhibition	111
Long non-coding RNA NORAD/miR-224-3p/MTDH axis contributes to CDDP resistance of esophageal squamous cell carcinoma by promoting nuclear accumulation of β-catenin	110
Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy	110
N6-methyladenosine-modified circIGF2BP3 inhibits CD8+ T-cell responses to facilitate tumor immune evasion by promoting the deubiquitination of PD-L1 in non-small cell lung cancer	110
Cancer neuroscience in head and neck: interactions, modulation, and therapeutic strategies	106
Molecular mechanisms of tumor resistance to radiotherapy	106
Correction to: Transcriptional inhibition by CDK7/9 inhibitor SNS-032 abrogates oncogene addiction and reduces liver metastasis in uveal melanoma	105
Correction: MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and facilitates immunotherapy in colorectal cancer	105
Activation-induced cytidine deaminase causes recurrent splicing mutations in diffuse large B-cell lymphoma	104
Correction: Long non-coding RNA GBCDRlnc1 induces chemoresistance of gallbladder cancer cells by activating autophagy	103
A PIK3CA-mutant breast cancer metastatic patient-derived organoid approach to evaluate alpelisib treatment for multiple secondary lesions	101
Inhibition of 6-phosphogluconate dehydrogenase suppresses esophageal squamous cell carcinoma growth and enhances the anti-tumor effects of metformin via the AMPK/mTOR pathway	101
Profiling of DNA damage and repair pathways in small cell lung cancer reveals a suppressive role in the immune landscape	101
CDC6 is a prognostic biomarker and correlated with immune infiltrates in glioma	100
Deciphering a profiling based on multiple post-translational modifications functionally associated regulatory patterns and therapeutic opportunities in human hepatocellular carcinoma	100
CircNFIB inhibits tumor growth and metastasis through suppressing MEK1/ERK signaling in intrahepatic cholangiocarcinoma	100
Unveiling the PDK4-centered rituximab-resistant mechanism in DLBCL: the potential of the “Smart” exosome nanoparticle therapy	99
N-glycosylation of PD-L1 modulates the efficacy of immune checkpoint blockades targeting PD-L1 and PD-1	98
Multimodal sequencing of neoadjuvant nivolumab treatment in hepatocellular carcinoma reveals cellular and molecular immune landscape for drug response	98
Size matters: integrating tumour volume and immune activation signatures predicts immunotherapy response	96
BID expression determines the apoptotic fate of cancer cells after abrogation of the spindle assembly checkpoint by AURKB or TTK inhibitors	96
Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients	95
A positive feedback circuit driven by m6A-modified circular RNA facilitates colorectal cancer liver metastasis	94
Hypoxia-induced lncRNA STEAP3-AS1 activates Wnt/β-catenin signaling to promote colorectal cancer progression by preventing m6A-mediated degradation of STEAP3 mRNA	94
An exosome-based liquid biopsy signature for pre-operative identification of lymph node metastasis in patients with pathological high-risk T1 colorectal cancer	94
Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age	94
Harnessing the MYB-dependent TAL1 5’super-enhancer for targeted therapy in T-ALL	94
PD1/PD-L1 blockade in clear cell renal cell carcinoma: mechanistic insights, clinical efficacy, and future perspectives	94
CircSMARCC1 facilitates tumor progression by disrupting the crosstalk between prostate cancer cells and tumor-associated macrophages via miR-1322/CCL20/CCR6 signaling	94
Targeting metastasis in paediatric bone sarcomas	93
Co-transcriptional R-loops-mediated epigenetic regulation drives growth retardation and docetaxel chemosensitivity enhancement in advanced prostate cancer	93
Present and future of cancer nano-immunotherapy: opportunities, obstacles and challenges	89
OLFM4 promotes the progression of intestinal metaplasia through activation of the MYH9/GSK3β/β-catenin pathway	89
A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma	88
The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin	88
Retraction Note: Systematic analyses reveal long non-coding RNA (PTAF)-mediated promotion of EMT and invasion-metastasis in serous ovarian cancer	87
Deciphering the tumor immune microenvironment from a multidimensional omics perspective: insight into next-generation CAR-T cell immunotherapy and beyond	87
PRMT7: a survive-or-die switch in cancer stem cells	86
Correction: Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway	85
Integration of pan-omics technologies and three-dimensional in vitro tumor models: an approach toward drug discovery and precision medicine	84
The role of lncRNAs and circRNAs in the PD-1/PD-L1 pathway in cancer immunotherapy	84
Exosomal miR-4745-5p/3911 from N2-polarized tumor-associated neutrophils promotes gastric cancer metastasis by regulating SLIT2	83
Reprogramming anchorage dependency by adherent-to-suspension transition promotes metastatic dissemination	82
Intracellular osteopontin protects from autoimmunity-driven lymphoma development inhibiting TLR9-MYD88-STAT3 signaling	82
Inflammation in cancer: therapeutic opportunities from new insights	82
BIRC2 blockade facilitates immunotherapy of hepatocellular carcinoma	81
Anti irradiation nanoparticles shelter immune organ from radio-damage via preventing the IKK/IκB/NF-κB activation	80
Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells	80
DNA methylation-associated dysregulation of transfer RNA expression in human cancer	80
Unveiling the immunomodulatory dance: endothelial cells’ function and their role in non-small cell lung cancer	80
Spatiotemporal metabolomic approaches to the cancer-immunity panorama: a methodological perspective	80
A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better	79
Role of a novel circRNA-CGNL1 in regulating pancreatic cancer progression via NUDT4–HDAC4–RUNX2–GAMT-mediated apoptosis	79
Epithelial-to-mesenchymal transition (EMT) and cancer metastasis: the status quo of methods and experimental models 2025	78
Circular RNA-encoded oncogenic PIAS1 variant blocks immunogenic ferroptosis by modulating the balance between SUMOylation and phosphorylation of STAT1	78
Cross-talk between cancer stem cells and immune cells: potential therapeutic targets in the tumor immune microenvironment	77
Biological and pharmacological roles of m6A modifications in cancer drug resistance	77
Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosis	77
A high proportion of germline variants in pediatric chronic myeloid leukemia	77
Identification of HSP90B1 in pan-cancer hallmarks to aid development of a potential therapeutic target	76
CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals	75
Pangaea Oncology, Dexeus University Hospital: bridging preclinical and clinical research	73
Glioma targeted therapy: insight into future of molecular approaches	73
Correction: Expression and inactivation of glycogen synthase kinase 3 alpha/ beta and their association with the expression of cyclin D1 and p53 in oral squamous cell carcinoma progression	73
CircVAPA promotes small cell lung cancer progression by modulating the miR-377-3p and miR-494-3p/IGF1R/AKT axis	73
Correction: Acyl-coenzyme a binding protein (ACBP) - a risk factor for cancer diagnosis and an inhibitor of immunosurveillance	73
SELP+ TEC:CD8+ T cell crosstalk associates with improved radiotherapy efficacy in cervical cancer	72
Proapoptotic activity of JNK-sensitive BH3-only proteins underpins ovarian cancer response to replication checkpoint inhibitors	71
Shifting landscapes of gender equity in oncology journals: a decade of authorship trends	71
Lung-specific metastasis: the coevolution of tumor cells and lung microenvironment	71
AMPK promotes antitumor immunity by downregulating PD-1 in regulatory T cells via the HMGCR/p38 signaling pathway	70
Retraction Note to: LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis	70
Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma	70

Exploring molecular and cellular mechanisms of Pre-Metastatic niche in renal cell carcinoma	69
Lysyl hydroxylase LH1 promotes confined migration and metastasis of cancer cells by stabilizing Septin2 to enhance actin network	68
Combined inhibition of Bcl-2 family members and YAP induces synthetic lethality in metastatic gastric cancer with RASA1 and NF2 deficiency	68
Chimeric antigen receptor macrophages targeting c-MET(CAR-M-c-MET) inhibit pancreatic cancer progression and improve cytotoxic chemotherapeutic efficacy	68
Proteomics technologies for cancer liquid biopsies	67
Deciphering resistance mechanisms in cancer: final report of MATCH-R study with a focus on molecular drivers and PDX development	67
Cuproptosis correlates with immunosuppressive tumor microenvironment based on pan-cancer multiomics and single-cell sequencing analysis	67
YTHDF2 in peritumoral hepatocytes mediates chemotherapy-induced antitumor immune responses through CX3CL1-mediated CD8+ T cell recruitment	67
Circular RNA circPOLR2A promotes clear cell renal cell carcinoma progression by facilitating the UBE3C-induced ubiquitination of PEBP1 and, thereby, activating the ERK signaling pathway	67
A comprehensive overview of ovarian cancer stem cells: correlation with high recurrence rate, underlying mechanisms, and therapeutic opportunities	66
Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells	66
Circular RNA ACVR2A promotes the progression of hepatocellular carcinoma through mir-511-5p targeting PI3K-Akt signaling pathway	66
An EHMT2/NFYA-ALDH2 signaling axis modulates the RAF pathway to regulate paclitaxel resistance in lung cancer	66
Immune dynamics shaping pre-metastatic and metastatic niches in liver metastases: from molecular mechanisms to therapeutic strategies	65
The role of m6A RNA methylation in cancer metabolism	65
Exploiting innate immunity for cancer immunotherapy	65
CircHERC1 promotes non-small cell lung cancer cell progression by sequestering FOXO1 in the cytoplasm and regulating the miR-142-3p-HMGB1 axis	65
Tumor metabolic regulators: key drivers of metabolic reprogramming and the promising targets in cancer therapy	65
A prospective multi-cohort study identifies and validates a 5-gene peripheral blood signature predictive of immunotherapy response in non-small cell lung cancer	64
Circulating cell-free DNA methylation patterns as non-invasive biomarkers to monitor colorectal cancer treatment efficacy without referencing primary site mutation profiles	64
Retraction Note: Quercetin-induced miR-200b-3p regulates the mode of self-renewing divisions in pancreatic cancer	64
Targeting TGF-β signal transduction for fibrosis and cancer therapy	64
Correction: The circROBO1/KLF5/FUS feedback loop regulates the liver metastasis of breast cancer by inhibiting the selective autophagy of afadin	64
Clustering cancers by shared transcriptional risk reveals novel targets for cancer therapy	64
Patient derived organoids in prostate cancer: improving therapeutic efficacy in precision medicine	63
Crosstalk between N6-methyladenosine modification and circular RNAs: current understanding and future directions	63
The application of organoids in investigating immune evasion in the microenvironment of gastric cancer and screening novel drug candidates	63
A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/β-catenin signaling pathway to promote gastric cancer progression	62
Extracellular vesicles in tumor immunity: mechanisms and novel insights	62
Hijacking of the nervous system in cancer: mechanism and therapeutic targets	61
Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translation	61
Diagnostic leukapheresis reveals distinct phenotypes of NSCLC circulating tumor cells	60
A novel NF-κB regulator encoded by circPLCE1 inhibits colorectal carcinoma progression by promoting RPS3 ubiquitin-dependent degradation	60
PDGFRβ promotes oncogenic progression via STAT3/STAT5 hyperactivation in anaplastic large cell lymphoma	60
Immunoproteasome function maintains oncogenic gene expression in KMT2A-complex driven leukemia	60
Expression of mTOR in normal and pathological conditions	60
Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells	60
Mapping cancer biology in space: applications and perspectives on spatial omics for oncology	58
Adoptive cellular immunotherapy for solid neoplasms beyond CAR-T	58
Essential gene screening identifies the bromodomain-containing protein BRPF1 as a new actionable target for endocrine therapy-resistant breast cancers	56
Combined proteomics and CRISPR‒Cas9 screens in PDX identify ADAM10 as essential for leukemia in vivo	56
Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches	55
i-CRISPR: a personalized cancer therapy strategy through cutting cancer-specific mutations	55
The circSPON2/miR-331-3p axis regulates PRMT5, an epigenetic regulator of CAMK2N1 transcription and prostate cancer progression	55
Targeting m7G-enriched circKDM1A prevents colorectal cancer progression	55
LINE-1 promotes tumorigenicity and exacerbates tumor progression via stimulating metabolism reprogramming in non-small cell lung cancer	55
Correction: CMTM6 overexpression confers trastuzumab resistance in HER2‑positive breast cancer	54
Correction: circCYP24A1 facilitates esophageal squamous cell carcinoma progression through binding PKM2 to regulate NF-κB-induced CCL5 secretion	54
The landscape of m6A regulators in small cell lung cancer: molecular characteristics, immuno-oncology features, and clinical relevance	54
The University of Kansas Cancer Center (KUCC), an NCI designated comprehensive cancer center	54
Correction: Comprehensive review of CRISPR‑based gene editing: mechanisms, challenges, and applications in cancer therapy	54
CAR T cells: engineered immune cells to treat brain cancers and beyond	53
The PI3K-AKT-mTOR axis persists as a therapeutic dependency in KRASG12D-driven non-small cell lung cancer	53
Lipid nanoparticles deliver DNA-encoded biologics and induce potent protective immunity	52
The mycobiome in human cancer: analytical challenges, molecular mechanisms, and therapeutic implications	52
Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer	52
circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4	52
circRNAs shed light on cancer diagnosis and treatment	51
Transfer RNA-derived small RNAs in tumor microenvironment	51
CircSTX6 promotes pancreatic ductal adenocarcinoma progression by sponging miR-449b-5p and interacting with CUL2	50
Mir-483-5p-mediated activating of IGF2/H19 enhancer up-regulates IGF2/H19 expression via chromatin loops to promote the malignant progression of hepatocellular carcinoma	50
A microRNA signature for risk-stratification and response prediction to FOLFOX-based adjuvant therapy in stage II and III colorectal cancer	50
Mechanism of ERBB2 gene overexpression by the formation of super-enhancer with genomic structural abnormalities in lung adenocarcinoma without clinically actionable genetic alterations	49
Writers, readers, and erasers RNA modifications and drug resistance in cancer	49
Splicing factor derived circular RNA circCAMSAP1 accelerates nasopharyngeal carcinoma tumorigenesis via a SERPINH1/c-Myc positive feedback loop	49
Deciphering the role of LGALS2: insights into tertiary lymphoid structure-associated dendritic cell activation and immunotherapeutic potential in breast cancer patients	49
Clinical application of liquid biopsy in colorectal cancer: detection, prediction, and treatment monitoring	49
PROTAC’ing oncoproteins: targeted protein degradation for cancer therapy	49
The epigenetic hallmarks of immune cells in cancer	48
BCL-2 expression promotes immunosuppression in chronic lymphocytic leukemia by enhancing regulatory T cell differentiation and cytotoxic T cell exhaustion	48
Traditional Chinese medicine in the treatment of breast Cancer	48
Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop	48
Retraction Note: N6-methyladenosine induced mir-143-3p promotes the brain metastasis of lung cancer via regulation of VASH1	47
The single cell transcriptional landscape of esophageal adenocarcinoma and its modulation by neoadjuvant chemotherapy	47
Mechanisms and cross-talk of regulated cell death and their epigenetic modifications in tumor progression	47
RAF inhibitor re-challenge therapy in BRAF-aberrant pan-cancers: the RE-RAFFLE study	47
Advances in immunotherapy for triple-negative breast cancer	47
NAC1 promotes stemness and regulates myeloid-derived cell status in triple-negative breast cancer	47
The journey of CAR-T therapy in hematological malignancies	47
Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy	47
Commentary on “Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth”	46
Spatial transcriptomic analysis of tumor microenvironment in esophageal squamous cell carcinoma with HIV infection	46
Correction: CircNTNG1 inhibits renal cell carcinoma progression via HOXA5-mediated epigenetic silencing of Slug	46
Overcoming multi-drug resistance in SCLC: a synergistic approach with venetoclax and hydroxychloroquine targeting the lncRNA LYPLAL1-DT/BCL2/BECN1 pathway	45
Targeting pyroptosis for cancer immunotherapy: mechanistic insights and clinical perspectives	45
M6A-Methylated circRAPGEF5 drives lung adenocarcinoma progression and metastasis via IGF2BP2/NUP160-mediated autophagy suppression	45
Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma	45
ADAR1-high tumor-associated macrophages induce drug resistance and are therapeutic targets in colorectal cancer	45
Metabolic targeting of regulatory T cells in oral squamous cell carcinoma: new horizons in immunotherapy	45
Pan-cancer drivers of metastasis	45
Clinical advances and challenges in targeting FGF/FGFR signaling in lung cancer	44
Genome-wide in vivo CRISPR screen identifies TGFβ3 as actionable biomarker of palbociclib resistance in triple negative breast cancer	44
Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia	44
Nanoparticles and bone microenvironment: a comprehensive review for malignant bone tumor diagnosis and treatment	43
The screening, identification, design and clinical application of tumor-specific neoantigens for TCR-T cells	43