OOIR: Observatory of International Research

Papers

(The H4-Index of Cell Communication and Signaling is 48. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC	363
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells	273
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress	218
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling	182
Epigenetic meets metabolism: novel vulnerabilities to fight cancer	163
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice	160
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis	157
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET2	145
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases	142
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury	131
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence	115
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells	111
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage	111
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types	107
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice	100
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation	98
Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response	88
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-2	83
Phase separation-mediated biomolecular condensates and their relationship to tumor	81
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis	80
The scaffold protein AXIN1: gene ontology, signal network, and physiological function	80
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish	79
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer	77
New insights into the regulation of METTL3 and its role in tumors	74
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases	72

RNA N6-methyladenosine modification in female reproductive biology and pathophysiology	72
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma	72
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis	71
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges	71
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression	67
Catalase-deficient mice induce aging faster through lysosomal dysfunction	64
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1	60
The role of lactate in cardiovascular diseases	60
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment	60
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor	57
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster	57
Microglial depletion decreases Müller cell maturation and inner retinal vascular density	55
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction	55
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice	55
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis	54
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes	54
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways	52
Roles of Twist1 in lipid and glucose metabolism	52
Correction: Anastasis: cell recovery mechanisms and potential role in cancer	52
Correction: LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure	50
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA	50
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activatio	49
Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT1	48
Correction: The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities	48
Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress	48