Cell Communication and Signaling

Papers
(The TQCC of Cell Communication and Signaling is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)
ArticleCitations
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC449
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells353
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor348
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish255
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage235
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation225
Knockout of thyroid hormone receptor alpha a (thraa) enhances cardiac regeneration in zebrafish through metabolic and hypoxic regulation206
The scaffold protein AXIN1: gene ontology, signal network, and physiological function194
Phase separation-mediated biomolecular condensates and their relationship to tumor175
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression156
Mitochondrial dysfunction in the regulation of aging and aging-related diseases150
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis147
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress141
The role of lactate in cardiovascular diseases139
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury116
Lycorine hydrochloride inhibits cholangiocarcinoma through cholesterol biosynthesis and PTPN11 nuclear translocation110
Caffeine mitigates ROS accumulation and attenuates motor neuron degeneration in the wobbler mouse model of amyotrophic lateral sclerosis109
MSP-RON signaling in liver pathobiology and as an emerging therapeutic target: a review of the current evidence108
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells106
Transmission Electron Microscopy-based characterization of Extracellular Vesicles from plasma and serum from Parkinson´s Disease patients106
LAMA4+ CD90+ eCAFs provide immunosuppressive microenvironment for liver cancer through induction of CD8+ T cell senescence103
Proteomic analysis of hydrogen peroxide-treated human chondrocytes shows endoplasmic reticulum stress, cytoskeleton remodeling, and altered secretome composition98
Catalase-deficient mice induce aging faster through lysosomal dysfunction93
Chemotherapy reprograms miRNA expression profiles in apoptotic extracellular vesicles from medulloblastoma cells, regulating pro- and anti-proliferative effects on recipient drug-naïve cells92
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-291
New insights into the regulation of METTL3 and its role in tumors89
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN189
Epigenetic meets metabolism: novel vulnerabilities to fight cancer88
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling88
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice84
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases83
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis81
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma80
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types79
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases78
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment77
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis71
The mitochondrial Ahi1/GR participates the regulation on mtDNA copy numbers and brain ATP levels and modulates depressive behaviors in mice70
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET268
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer68
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology67
MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis66
Correction: LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure66
TGF-β1 regulates chondrocyte proliferation and extracellular matrix synthesis via circPhf21a-Vegfa axis in osteoarthritis66
LRSAM1 mediated the degradation of intracellular Vibrio through the ubiquitination-autophagy-lysosome pathway in oyster66
Klebsiella pneumoniae-derived extracellular vesicles impair endothelial function by inhibiting SIRT166
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges66
Dual regulation of the levels and function of Start transcriptional repressors drives G1 arrest in response to cell wall stress65
HAX1 inhibits apoptosis and promotes maturation of neutrophils64
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis63
Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways62
Correction: Anastasis: cell recovery mechanisms and potential role in cancer61
IL-23 promotes neuronal ferroptosis via IL-23R/STAT3 signaling after traumatic brain injury61
TGFβ1-induced hedgehog signaling suppresses the immune response of brain microvascular endothelial cells elicited by meningitic Escherichia coli60
Correction: The importance of claudin-7 palmitoylation on membrane subdomain localization and metastasis-promoting activities60
Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells59
Motor skill learning modulates striatal extracellular vesicles’ content in a mouse model of Huntington’s disease59
E3 ubiquitin ligase RNF128 negatively regulates the IL-3/STAT5 signaling pathway by facilitating K27-linked polyubiquitination of IL-3Rα58
Melanoma stimulates the proteolytic activity of HaCaT keratinocytes56
The primary cilium as a multifunctional organelle: emerging roles and unanswered questions56
Terphenyllin induces CASP3-dependent apoptosis and pyroptosis in A375 cells through upregulation of p5356
Intrauterine administration of peripheral blood mononuclear cells helps manage recurrent implantation failure by normalizing dysregulated gene expression including estrogen-responsive genes in mice56
RepID represses megakaryocytic differentiation by recruiting CRL4A-JARID1A at DAB2 promoter53
Targeting HGF/c-MET signaling to regulate the tumor microenvironment: Implications for counteracting tumor immune evasion52
Extracellular vesicles of the probiotic bacteria E. coli O83 activate innate immunity and prevent allergy in mice52
Reciprocal regulation of TWIST1 and OGT determines the decitabine efficacy in MDS/AML52
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression51
Mitochondria facilitate neuronal differentiation by metabolising nuclear-encoded RNA51
MICALL2 as a substrate of ubiquitinase TRIM21 regulates tumorigenesis of colorectal cancer51
Increased levels of villus-derived exosomal miR-29a-3p in normal pregnancy than uRPL patients suppresses decidual NK cell production of interferon-γ and exerts a therapeutic effect in abortion-prone m51
Dual inhibition of GTP-bound KRAS and mTOR in lung adenocarcinoma and squamous cell carcinoma harboring KRAS G12C50
Role of liver sinusoidal endothelial cell in metabolic dysfunction-associated fatty liver disease50
Signaling pathways, microenvironment, and targeted treatments in Langerhans cell histiocytosis50
The dynamic shifts of IL-10-producing Th17 and IL-17-producing Treg in health and disease: a crosstalk between ancient "Yin-Yang" theory and modern immunology50
Evidence that CRISPR-Cas9 Y537S-mutant expressing breast cancer cells activate Yes-associated protein 1 to driving the conversion of normal fibroblasts into cancer-associated fibroblasts50
NAT10 mediated ac4C acetylation driven m6A modification via involvement of YTHDC1-LDHA/PFKM regulates glycolysis and promotes osteosarcoma50
Ionizing radiation-induced disruption of Rela-Bclaf1-spliceosome regulatory axis in primary spermatocytes causing spermatogenesis dysfunction49
Roles of Twist1 in lipid and glucose metabolism47
Communication between cells: exosomes as a delivery system in prostate cancer47
Correction: Human Parathyroid Hormone Analog (3–34/29–34) promotes wound re-epithelialization through inducing keratinocyte migration and epithelial–mesenchymal transition via PTHR1-PI3K/AKT activatio46
Role of DEAD/DEAH-box helicases in immunity, infection and cancers46
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways45
Functionalized exosomes for targeted therapy in cancer and regenerative medicine: genetic, chemical, and physical modifications45
Castration promotes the browning of the prostate tumor microenvironment45
GLUT1 promotes cell proliferation via binds and stabilizes phosphorylated EGFR in lung adenocarcinoma44
Microglial depletion decreases Müller cell maturation and inner retinal vascular density44
Identification of biological pathways and processes regulated by NEK5 in breast epithelial cells via an integrated proteomic approach44
O-GlcNAcylation: roles and potential therapeutic target for bone pathophysiology44
The role of miR-155-5p in inflammation and mechanical loading during intervertebral disc degeneration44
The roles of different microRNAs in the regulation of cholesterol in viral hepatitis43
An update of Nrf2 activators and inhibitors in cancer prevention/promotion43
Nanobodies and their derivatives: pioneering the future of cancer immunotherapy43
Andrew H. Wyllie, a pioneer in the field of apoptosis42
Emerging roles of the Protein Phosphatase 1 (PP1) in the context of viral infections42
Correction: MicroRNA-644a promotes apoptosis of hepatocellular carcinoma cells by downregulating the expression of heat shock factor 142
Non-canonical non-genomic morphogen signaling in anucleate platelets: a critical determinant of prothrombotic function in circulation41
Outcomes of physical exercises on initiation, progression, and treatment of breast cancer41
PGC7 regulates maternal mRNA translation via AKT1-YBX1 interactions in mouse oocytes41
OTU deubiquitinase, ubiquitin aldehyde binding 2  (OTUB2) modulates the stemness feature, chemoresistance, and epithelial-mesenchymal transition of colon cancer via regulating GINS complex subunit 1 (40
Neuropilin1-dependent paracrine signaling of cancer cells mediated by miRNA exosomal cargo40
The long non-coding RNA LINC00707 interacts with Smad proteins to regulate TGFβ signaling and cancer cell invasion40
IRE1-mediated degradation of pre-miR-301a promotes apoptosis through upregulation of GADD45A40
Design of stable circular permutants of the GroEL chaperone apical domain40
Lactate shuttle between cytotrophoblast and syncytiotrophoblast in the placenta enhances ferroptosis resistance and maintains placental homeostasis: implications for early pregnancy loss39
Beyond the G protein α subunit: investigating the functional impact of other components of the Gαi3 heterotrimers38
Mechanisms underlying neutrophils adhesion to triple-negative breast cancer cells via CD11b-ICAM1 in promoting breast cancer progression38
N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis38
Natural killer cells and their exosomes in viral infections and related therapeutic approaches: where are we?38
Mitochondrial dynamics and colorectal cancer biology: mechanisms and potential targets38
Exosome-transmitted HSPA9 facilitates bortezomib resistance by targeting TRIP13/USP1 signaling in multiple myeloma38
Acidic preconditioning induced intracellular acid adaptation to protect renal injury via dynamic phosphorylation of focal adhesion kinase-dependent activation of sodium hydrogen exchanger 138
Emerging roles and biomarker potential of WNT6 in human cancers38
The role of KLRG1: a novel biomarker and new therapeutic target37
The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis37
Correction: Receptor tyrosine kinases Tyro3, Axl, and Mertk differentially contribute to antibody-induced arthritis37
Semaphorin3f as a cardiomyocyte derived regulator of heart chamber development36
Campylobacter jejuni regulates cell cycle progression to potentiate host cell invasion36
Characterization of two melanoma cell lines resistant to BRAF/MEK inhibitors (vemurafenib and cobimetinib)36
Extracellular vesicles in Helicobacter pylori-mediated diseases: mechanisms and therapeutic potential36
Cellular and micro-environmental responses influencing the antitumor activity of all-trans retinoic acid in breast cancer35
Neutrophil extracellular traps promote angiogenesis in gastric cancer35
cGAS-STING, inflammasomes and pyroptosis: an overview of crosstalk mechanism of activation and regulation35
Tumor-derived miR-6794-5p enhances cancer growth by promoting M2 macrophage polarization35
Advances in the study of exosomes derived from mesenchymal stem cells and cardiac cells for the treatment of myocardial infarction35
Antizyme inhibitor family: biological and translational research implications35
Trogocytosis in CAR immune cell therapy: a key mechanism of tumor immune escape35
Pyroptosis, ferroptosis, and autophagy cross-talk in glioblastoma opens up new avenues for glioblastoma treatment34
Cellular crosstalk in atherosclerotic plaque microenvironment34
Glycosylation as an intricate post-translational modification process takes part in glycoproteins related immunity34
ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway34
Regulated cell death: discovery, features and implications for neurodegenerative diseases34
Tumor immunotherapies by immune checkpoint inhibitors (ICIs); the pros and cons34
Streptococcus pneumoniae disrupts the structure of the golgi apparatus and subsequent epithelial cytokine response in an H2O2-dependent manner34
The significant role of amino acid metabolic reprogramming in cancer34
Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC133
Unraveling the role of hypoxia-inducible factors in cutaneous melanoma: from mechanisms to therapeutic opportunities33
Sirtuins in kidney diseases: potential mechanism and therapeutic targets33
An attempt to explain what intrinsically disordered TCF4 does in its spare time when PTHS-related mutations prevent it from doing its job33
Correction: Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis33
Selective Pyk2 inhibition enhances bone restoration through SCARA5-mediated bone marrow remodeling in ovariectomized mice32
Distinct roles of centriole distal appendage proteins in ciliary assembly and disassembly32
Exercise-conditioned plasma ameliorates postoperative cognitive dysfunction by activating hippocampal cholinergic circuit and enhancing BDNF/TrkB signaling32
Whole-gene CRISPR/cas9 library screen revealed targeting STAT6 increased the sensitivity of liver cancer to celecoxib via inhibiting arachidonic acid shunting32
The cancer-associated fibroblast facilitates YAP liquid-liquid phase separation to promote cancer cell stemness in HCC32
Human mesenchymal stroma/stem-like cell-derived taxol-loaded EVs/exosomes transfer anti-tumor microRNA signatures and express enhanced SDF-1-mediated tumor tropism32
c-MYC mediates the crosstalk between breast cancer cells and tumor microenvironment31
NEDD4L mediates ITGB4 ubiquitination and degradation to suppress esophageal carcinoma progression31
Multiomics analysis revealed the mechanisms related to the enhancement of proliferation, metastasis and EGFR-TKI resistance in EGFR-mutant LUAD with ARID1A deficiency31
Co-culture engineering: a promising strategy for production of engineered extracellular vesicle for osteoarthritis treatment31
Correction: Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome31
Targeting Endocytosis  and Cell Communications  in the Tumor Immune Microenvironment31
Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells31
Photomodulation alleviates cellular senescence of aging adipose-derived stem cells31
The c-Abl-RACK1-FAK signaling axis promotes renal fibrosis in mice through regulating fibroblast-myofibroblast transition31
Plasma circulating extracellular vesicles reveal dysregulation of synaptic signaling in SHIV-infected rhesus macaque30
Docetaxel suppressed cell proliferation through Smad3/HIF-1α-mediated glycolysis in prostate cancer cells30
Nuclear import of Mas-related G protein-coupled receptor member D induces pathological cardiac remodeling30
Involvement of HDAC2-mediated kcnq2/kcnq3 genes transcription repression activated by EREG/EGFR-ERK-Runx1 signaling in bone cancer pain30
CRABP1-complexes in exosome secretion30
Arginyltransferase 1 modulates p62-driven autophagy via mTORC1/AMPk signaling29
IGFBP5 is released by senescent cells and is internalized by healthy cells, promoting their senescence through interaction with retinoic receptors29
Metrnl: a promising biomarker and therapeutic target for cardiovascular and metabolic diseases29
Effects of platelet-rich fibrin on osteogenic differentiation of Schneiderian membrane derived mesenchymal stem cells and bone formation in maxillary sinus29
Programmed cell death disrupts inflammatory tumor microenvironment (TME) and promotes glioblastoma evolution29
Change in cytokine profiles released by mast cells mediated by lung cancer-derived exosome activation may contribute to cancer-associated coagulation disorders29
eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling28
Novel energy optimizer, meldonium, rapidly restores acute hypobaric hypoxia-induced brain injury by targeting phosphoglycerate kinase 128
Reconstruction and analysis of a large-scale binary Ras-effector signaling network28
Frizzled class receptor 5 contributes to ovarian cancer chemoresistance through aldehyde dehydrogenase 1A128
Upregulated FSP1 by GPD1/1L mediated lipid droplet accumulation enhances ferroptosis resistance and peritoneal metastasis in gastric cancer28
Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo28
The impact of lipid metabolism on breast cancer: a review about its role in tumorigenesis and immune escape27
Targeting Wnt/β-catenin signaling and its interplay with TGF-β and Notch signaling pathways for the treatment of chronic wounds27
Elucidating the molecular mechanisms underlying the induction of autophagy by antidepressant-like substances in C57BL/6J mouse testis model upon LPS challenge27
Cancer immune evasion through KRAS and PD-L1 and potential therapeutic interventions27
AIP1 suppresses neovascularization by inhibiting the NOX4-induced NLRP3/NLRP6 imbalance in a murine corneal alkali burn model27
The efferocytosis dilemma: how neutrophil extracellular traps and PI3K/Rac1 complicate diabetic wound healing27
Mechanisms, combination therapy, and biomarkers in cancer immunotherapy resistance27
Therapeutic targeting of the TPX2/TTK network in colorectal cancer27
Emerging roles of liquid-liquid phase separation in liver innate immunity27
The CD6 interactome orchestrates ligand-independent T cell inhibitory signaling27
Enhancing intestinal epithelial microtubule stability could alleviate IBD symptoms26
Extracellular vesicles from UTX-knockout endothelial cells boost neural stem cell differentiation in spinal cord injury26
Deubiquitinase MYSM1 promotes doxorubicin-induced cardiotoxicity by mediating TRIM21-ferroptosis axis in cardiomyocytes26
Off-target engagement of sotorasib with PPARγ via FABP4: a novel mechanism driving interstitial lung disease26
ATP purinergic receptor signalling promotes Sca-1+ cell proliferation and migration for vascular remodelling26
Full-length and N-terminally truncated recombinant interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors26
Correction: SUMOylation-induced membrane localization of TRPV1 suppresses proliferation and migration in gastric cancer cells26
(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota26
The interaction of inflammasomes and gut microbiota: novel therapeutic insights25
Targeting cellular senescence in kidney diseases and aging: A focus on mesenchymal stem cells and their paracrine factors25
Helicobacter pylori promotes gastric intestinal metaplasia through activation of IRF3-mediated kynurenine pathway25
Progress on multifunctional transmembrane protein ATG9A25
Inhibition of bromodomain and extra-terminal proteins targets constitutively active NFκB and STAT signaling in lymphoma and influences the expression of the antiapoptotic proteins BCL2A1 and c-MYC25
Tumorigenic and tumoricidal properties of exosomes in cancers; a forward look25
Modulating voltage-gated sodium channels to enhance differentiation and sensitize glioblastoma cells to chemotherapy25
RNF20/RNF40 supports the aggressive behavior in cervical cancer by regulating a peroxisome-based anti-ferroptotic mechanism25
Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts25
Arachidonic acid impairs natural killer cell functions by disrupting signaling pathways driven by activating receptors and reactive oxygen species25
Supplementation of spermidine enhances the quality of postovulatory aged porcine oocytes25
Epigenetic modulation of the NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection25
Neutrophil degranulation and myocardial infarction25
The scaffold protein DLG4 facilitates RNF63-mediated ubiquitination and degradation of STAT3 in non-small cell lung cancer25
Intratumoral microbiota in colorectal cancer: focus on specific distribution and potential mechanisms25
CD73/adenosine axis exerts cardioprotection against hypobaric hypoxia-induced metabolic shift and myocarditis in a sex-dependent manner25
Cellular signaling modulated by miRNA-3652 in ovarian cancer: unveiling mechanistic pathways for future therapeutic strategies25
NEK8, a NIMA-family protein kinase at the core of the ciliary INV complex24
The Golgi stacking protein GRASP55 is targeted by the natural compound prodigiosin24
The role of exhausted natural killer cells in the immunopathogenesis and treatment of leukemia24
Evidence for a JAK2/STAT3 proinflammatory and vasculogenic mimicry interrelated molecular signature in adipocyte-derived mesenchymal stromal/stem cells24
The crucial role of intercellular calcium wave propagation triggered by influenza A virus in promoting infection24
Machine learning-based in-silico analysis identifies signatures of lysyl oxidases for prognostic and therapeutic response prediction in cancer24
The SMYD3-dependent H3K4me3 status of IGF2 intensifies local Th2 differentiation in CRSwNP via positive feedback24
N-glycosylation acts as a switch for FGFR1 trafficking between the plasma membrane and nuclear envelope24
Cerebral Semaphorin3D is a novel risk factor for age-associated cognitive impairment24
High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes24
ER-phagy mediates the anti-tumoral synergism between HDAC inhibition and chemotherapy24
Artificial intelligence-driven discovery of YH395A: A novel TGFβR1 inhibitor with potent anti-tumor activity against triple-negative breast cancer24
The role of bone marrow microenvironment (BMM) cells in acute myeloid leukemia (AML) progression: immune checkpoints, metabolic checkpoints, and signaling pathways24
Effects of macrophages on the proliferation and cardiac differentiation of human induced pluripotent stem cells24
Integrin signaling in cancer: bidirectional mechanisms and therapeutic opportunities23
NFAT1 and NFκB regulates expression of the common γ-chain cytokine receptor in activated T cells23
Protein disulfide isomerase plays a crucial role in mediating chemically-induced, glutathione depletion-associated hepatocyte injury in vitro and in vivo23
An integrated systems biology approach establishes arginine biosynthesis as a metabolic weakness in Candida albicans during host infection23
Role of miRNAs interference on ovarian functions and premature ovarian failure23
Neutrophil extracellular traps induced by the hypoxic microenvironment in gastric cancer augment tumour growth23
Neuroangiogenesis potential of mesenchymal stem cell extracellular vesicles in ischemic stroke conditions23
UHMK1-dependent phosphorylation of Cajal body protein coilin alters 5-FU sensitivity in colon cancer cells23
GZMA suppressed GPX4-mediated ferroptosis to improve intestinal mucosal barrier function in inflammatory bowel disease23
IL-33-mediated activation of mast cells is involved in the progression of imiquimod-induced psoriasis-like dermatitis23
Correction: Endomucin selectively regulates vascular endothelial growth factor receptor-2 endocytosis through its interaction with AP223
RNF13 protects neurons against ischemia-reperfusion injury via stabilizing p62-mediated Nrf2/HO-1 signaling pathway23
Notch ankyrin domain: evolutionary rise of a thermodynamic sensor23
Disulfidptosis: a novel cell death modality induced by actin cytoskeleton collapse and a promising target for cancer therapeutics23
Lamprey immune protein triggers the ferroptosis pathway during zebrafish embryonic development22
Correction: Androgens as the “old age stick” in skeletal muscle22
The RNA binding protein IGF2BP2/IMP2 alters the cargo of cancer cell-derived extracellular vesicles supporting tumor-associated macrophages22
Mitochondria-derived methylmalonic acid aggravates ischemia–reperfusion injury by activating reactive oxygen species-dependent ferroptosis22
Reversible arginine methylation of PI3KC2α controls mitotic spindle dynamics22
ER–mitochondria contact sites regulate hepatic lipogenesis via Ip3r-Grp75-Vdac complex recruiting Seipin22
BTN3A1 expressed in cervical cancer cells promotes Vγ9Vδ2 T cells exhaustion through upregulating transcription factors NR4A2/3 downstream of TCR signaling22
Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease22
Interleukin-1 receptor antagonist inhibits metastatic potential by down-regulating CXCL12/CXCR4 signaling axis in colorectal cancer22
Hydrogen sulfide induces regulatory B cells via glycolysis and mitochondrial ROS, attenuating LPS-induced lung injury22
Deciphering the dynamics of methicillin-resistant Staphylococcus aureus biofilm formation: from molecular signaling to nanotherapeutic advances22
ERK2-mediated phosphorylation of ZEB1 at S322 enhances PD-L1 expression and EMT, leading to pancreatic cancer progression22
Matrix stiffness-induced IKBKE and MAPK8 signaling drives a phenotypic switch from DCIS to invasive breast cancer22
The B56γ3-containing protein phosphatase 2A attenuates p70S6K-mediated negative feedback loop to enhance AKT-facilitated epithelial-mesenchymal transition in colorectal cancer22
COVID-19 in patients with anemia and haematological malignancies: risk factors, clinical guidelines, and emerging therapeutic approaches22
tRF-His-GTG-1 enhances NETs formation and interferon-α production in lupus by extracellular vesicle22
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