Cell Communication and Signaling

Papers
(The TQCC of Cell Communication and Signaling is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)
ArticleCitations
Meeting report: International Symposium on Mitochondria, Cell Death and Human Diseases: Jawaharlal Nehru University, New Delhi, India, February 18–19, 20231063
Revealing role of epigenetic modifiers and DNA oxidation in cell-autonomous regulation of Cancer stem cells330
K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3264
In vitro effect of hCG on cryptorchid patients’ gubernacular cells: a predictive model for adjuvant personalized therapy251
Immunomodulatory effect of efferocytosis at the maternal–fetal interface179
VEGFR3 mitigates hypertensive nephropathy by enhancing mitophagy via regulating crotonylation of HSPA1L159
Soluble E-cadherin contributes to inflammation in acute lung injury via VEGF/VEGFR2 signaling144
TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated lipophagy143
Specific sDMA modifications on the RGG/RG motif of METTL14 regulate its function in AML139
Revealing the role of RAB27 in HER receptor family expression and signaling in melanoma cells131
Peroxiredoxin II regulates exosome secretion from dermal mesenchymal stem cells through the ISGylation signaling pathway120
Bone mesenchymal stem cell extracellular vesicles delivered miR let-7-5p alleviate endothelial glycocalyx degradation and leakage via targeting ABL2116
The dynamic role of nucleoprotein SHCBP1 in the cancer cell cycle and its potential as a synergistic target for DNA-damaging agents in cancer therapy108
Neuromedin U secreted by colorectal cancer cells promotes a tumour-supporting microenvironment100
Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival100
Dopamine enhances recovery after traumatic brain injury through ubiquitylation and autophagic degradation of RIPK195
Correction: Intrinsic disorder in PRAME and its role in uveal melanoma91
A specific, non-immune system-related isoform of the human inducible nitric oxide synthase is expressed during differentiation of human stem cells into various cell types84
N6-methyladenosine (m6A) methyltransferase WTAP-mediated miR-92b-5p accelerates osteoarthritis progression82
ZMAT2 condensates regulate the alternative splicing of TRIM28 to reduce cellular ROS accumulation, thereby promoting the proliferation of HCC cells78
Jak2/STAT6/c-Myc pathway is vital to the pathogenicity of Philadelphia-positive acute lymphoblastic leukemia caused by P190BCR-ABL72
ER stress inhibition enhances formation of triacylglcerols and protects endothelial cells from lipotoxicity72
Dose-dependent role of AMH and AMHR2 signaling in male differentiation and regulation of sex determination in Spotted knifejaw (Oplegnathus punctatus) with X1X1X2X2/X1X2Y chromosome system71
Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer71
NLRP3: a key regulator of skin wound healing and macrophage-fibroblast interactions in mice70
Atg5 deficiency in basophils improves metabolism in lupus mice by regulating gut microbiota dysbiosis67
Protease-activated receptors in vascular smooth muscle cells: a bridge between thrombo-inflammation and vascular remodelling67
IRG1/itaconate enhances efferocytosis by activating Nrf2-TIM4 signaling pathway to alleviate con A induced autoimmune liver injury67
Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis63
Transforming growth factor-β1 negatively regulates SOCS7 via EGR1 during wound healing61
KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion57
Induction of DNMT1-dependent demethylation of SHP-1 by the natural flavonoid compound Baicalein overcame Imatinib-resistance in CML CD34+ cells57
Fibroblast growth factor signaling in axons: from development to disease56
NEK8 regulates colorectal cancer progression via phosphorylating MYC55
USP9X-mediated deubiquitination of Raptor contributes to autophagy impairment and memory deficits in P301S mice53
Targeting the hedgehog pathway in MET mutation cancers and its effects on cells associated with cancer development53
Role of scaffold proteins in the heterogeneity of glioblastoma51
Optogenetic control of NOTCH1 signaling50
Machine learning-based analysis of cancer cell-derived vesicular proteins revealed significant tumor-specificity and predictive potential of extracellular vesicles for cell invasion and proliferation 50
Crosstalk between protein post-translational modifications and phase separation50
Lipid kinase PIP5Kα contributes to Hippo pathway activation via interaction with Merlin and by mediating plasma membrane targeting of LATS150
The interplay of cancer-associated fibroblasts and apoptotic cancer cells suppresses lung cancer cell growth through WISP-1-integrin ανβ3-STAT1 signaling pathway48
Adenosine A2A receptor-mediated interactions between Th1+ T cells and the choroid plexus epithelium via IFN-γ signalling control T-Cell infiltration in experimental autoimmune encephalomyelitis47
HIF1α controls steroidogenesis under acute hypoxic stress47
Comparative functional analysis of a new CDR1-like ABC transporter gene in multidrug resistance and virulence between Magnaporthe oryzae and Trichophyton mentagrophytes47
Mutual impact of adipocytes and colorectal cancer cells growing in co-culture conditions46
p53-regulated SESN1 and SESN2 regulate cell proliferation and cell death through control of STAT346
Vitamin D impedes eosinophil chemotaxis via inhibiting glycolysis-induced CCL26 expression in eosinophilic chronic rhinosinusitis with nasal polyps46
Exosomal lncRNA Mir100hg derived from cancer stem cells enhance glycolysis and promote metastasis of lung adenocarcinoma through mircroRNA-15a-5p/31-5p45
Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis44
TRAF6-mediated ubiquitination of AKT in the nucleus is a critical event underlying the desensitization of G protein-coupled receptors44
Analysis of early effects of human APOE isoforms on Alzheimer’s disease and type III hyperlipoproteinemia pathways using knock-in rat models with humanized APP and APOE44
Broadening horizons: molecular mechanisms and disease implications of endothelial-to-mesenchymal transition44
Microvesicles from bone marrow-derived mesenchymal stem cells promote Helicobacter pylori-associated gastric cancer progression by transferring thrombospondin-244
ATXN3 promotes prostate cancer progression by stabilizing YAP44
PD-1 interactome in osteosarcoma: identification of a novel PD-1/AXL interaction conserved between humans and dogs43
Exosomal AP000439.2 from clear cell renal cell carcinoma induces M2 macrophage polarization to promote tumor progression through activation of STAT343
Dust mite antigens endow dendritic cells with the capacity to induce a Th2 response by regulating their methylation profiles43
V-ATPase in cancer: mechanistic insights and therapeutic potentials43
Targeting CD24 as a novel immunotherapy for solid cancers42
Bivalent chromatin accommodates survivin and BRG1/SWI complex to activate DNA damage response in CD4+ cells41
YAP-mediated trophoblast dysfunction: the common pathway underlying pregnancy complications41
The Prognostic and therapeutic value and clinical implications of fibroblast activation protein-α as a novel biomarker in colorectal cancer41
The prognostic and therapeutic potential of HO-1 in leukemia and MDS41
A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology41
Tumor-associated macrophage-derived itaconic acid contributes to nasopharyngeal carcinoma progression by promoting immune escape via TET239
NAD+ enhancers as therapeutic agents in the cardiorenal axis39
CXCR4 regulates macrophage M1 polarization by altering glycolysis to promote prostate fibrosis38
MiR-574-5p activates human TLR8 to promote autoimmune signaling and lupus38
THZ1 targeting CDK7 suppresses c-KIT transcriptional activity in gastrointestinal stromal tumours37
Intracellular cholesterol transport inhibition Impairs autophagy flux by decreasing autophagosome–lysosome fusion37
UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN137
Spatial-transcriptomic profiling: a new lens for understanding myelofibrosis pathophysiology37
Lrpap1 deficiency leads to myopia through TGF-β-induced apoptosis in zebrafish36
FKBP12 is a major regulator of ALK2 activity in multiple myeloma cells36
Catalase-deficient mice induce aging faster through lysosomal dysfunction36
KLF4-mediated upregulation of the NKG2D ligand MICA in acute myeloid leukemia: a novel therapeutic target identified by enChIP36
Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer35
Eukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity34
Single-cell RNA sequencing reveals enhanced antitumor immunity after combined application of PD-1 inhibitor and Shenmai injection in non-small cell lung cancer33
Migrasomes, a new mode of intercellular communication33
Genetic screening for anticancer genes highlights FBLN5 as a synthetic lethal partner of MYC32
Enhancer RNAs: mechanisms in transcriptional regulation and functions in diseases32
α-catenin interaction with YAP/FoxM1/TEAD-induced CEP55 supports liver cancer cell migration32
Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways32
Concomitant induction of SLIT3 and microRNA-218–2 in macrophages by toll-like receptor 4 activation limits osteoclast commitment32
DJ-1 preserves ischemic postconditioning-induced cardioprotection in STZ-induced type 1 diabetic rats: role of PTEN and DJ-1 subcellular translocation31
The protein phosphatase-2A subunit PR130 is involved in the formation of cytotoxic protein aggregates in pancreatic ductal adenocarcinoma cells31
Extracellular vesicles containing MFGE8 from colorectal cancer facilitate macrophage efferocytosis30
Influence of intersignaling crosstalk on the intracellular localization of YAP/TAZ in lung cells30
Bcl-2 dependent modulation of Hippo pathway in cancer cells30
Platelet-derived extracellular vesicles induced through different activation pathways drive melanoma progression by functional and transcriptional changes29
Oncogenic potential of SARS-CoV-2—targeting hallmarks of cancer pathways29
Identification of critical residues at the C-terminal tip of ACKR4 regulating chemokine internalization and βarrestin involvement29
The gut microbiome, chronic kidney disease, and sarcopenia29
Exercise alleviates hematopoietic stem cell injury following radiation via the carnosine/Slc15a2-p53 axis29
Neutrophil extracellular traps facilitate liver inflammation/fibrosis progression by entering macrophages and triggering AIM2 inflammasome-dependent pyroptosis29
miR-1250-5p is a novel tumor suppressive intronic miRNA hypermethylated in non-Hodgkin’s lymphoma: novel targets with impact on ERK signaling and cell migration28
E-cadherin variants associated with oral facial clefts trigger aberrant cell motility in a REG1A-dependent manner28
Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired prog28
Metabolic self-feeding in HBV-associated hepatocarcinoma centered on feedback between circulation lipids and the cellular MAPK/mTOR axis28
Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression28
Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease28
Investigation of the impact of bromodomain inhibition on cytoskeleton stability and contraction28
The complex interplay of tumor-infiltrating cells in driving therapeutic resistance pathways27
Influenza virus infection activates TAK1 to suppress RIPK3-independent apoptosis and RIPK1-dependent necroptosis27
Olanzapine suppresses mPFC activity-norepinephrine releasing to alleviate CLOCK-enhanced cancer stemness under chronic stress27
Knockdown of trem2 promotes proinflammatory microglia and inhibits glioma progression via the JAK2/STAT3 and NF-κB pathways27
Podoplanin depletion in tonsil-derived mesenchymal stem cells induces cellular senescence via regulation of the p16Ink4a/Rb pathway27
All-trans retinoic acid pretreatment of mesenchymal stem cells enhances the therapeutic effect on acute kidney injury27
Histone variant H2AZ1 drives lung cancer progression through the RELA-HIF1A-EGFR signaling pathway26
Nesfatin-1 enhances vascular smooth muscle calcification through facilitating BMP-2 osteogenic signaling26
SUMOylation-induced membrane localization of TRPV1 suppresses proliferation and migration in gastric cancer cells26
Ascorbic acid alleviates rheumatoid arthritis by inhibiting the production of autoantibodies26
TonEBP inhibits ciliogenesis by controlling aurora kinase A and regulating centriolar satellite integrity26
Gasdermin D deficiency aborts myeloid calcium influx to drive granulopoiesis in lupus nephritis26
Gamma-glutamyl transferase secreted by Helicobacter pylori promotes the development of gastric cancer by affecting the energy metabolism and histone methylation status of gastric epithelial cells26
ASIC3-activated key enzymes of de novo lipid synthesis supports lactate-driven EMT and the metastasis of colorectal cancer cells26
Lanthanide conjugate Pr-MPO elicits anti-cancer activity by targeting lysosomal machinery and inducing zinc-dependent cataplerosis25
γ-Enolase enhances Trk endosomal trafficking and promotes neurite outgrowth in differentiated SH-SY5Y cells25
Interactions between hedgehog signaling pathway and the complex tumor microenvironment in breast cancer: current knowledge and therapeutic promises25
Correction: Epigenetic silencing and tumor suppressor gene of HAND2 by targeting ERK signaling in colorectal cancer25
STING protects against cardiac dysfunction and remodelling by blocking autophagy25
The role of nonmyocardial cells in the development of diabetic cardiomyopathy and the protective effects of FGF21: a current understanding25
Multiomic analysis on human cell model of wolfram syndrome reveals changes in mitochondrial morphology and function25
Opportunities and challenges of glioma organoids25
Drug delivery strategy in hepatocellular carcinoma therapy24
CYP1B1-catalyzed 4-OHE2 promotes the castration resistance of prostate cancer stem cells by estrogen receptor α-mediated IL6 activation24
Role of store-operated Ca2+ entry in cardiovascular disease24
Combination of artesunate and WNT974 induces KRAS protein degradation by upregulating E3 ligase ANACP2 and β-TrCP in the ubiquitin–proteasome pathway24
Insights into the diverse mechanisms and effects of variant CUL3-induced familial hyperkalemic hypertension23
Ten-eleven translocation-2-mediated macrophage activation promotes liver regeneration23
IDH2/R140Q mutation confers cytokine-independent proliferation of TF-1 cells by activating constitutive STAT3/5 phosphorylation23
GETV nsP2 plays a critical role in the interferon antagonism and viral pathogenesis23
Egr-1 is a key regulator of the blood-brain barrier damage induced by meningitic Escherichia coli23
Adipo-oncology: adipocyte-derived factors govern engraftment, survival, and progression of metastatic cancers23
Paracrine secretion of IL8 by breast cancer stem cells promotes therapeutic resistance and metastasis of the bulk tumor cells22
Promoting AMPK/SR-A1-mediated clearance of HMGB1 attenuates chemotherapy-induced peripheral neuropathy22
Correction: Multiregion WES of metastatic pancreatic neuroendocrine tumors revealed heterogeneity in genomic alterations, immune microenvironment and evolutionary patterns22
Phase separation-mediated biomolecular condensates and their relationship to tumor22
Glycosaminoglycan modifications of betaglycan regulate ectodomain shedding to fine-tune TGF-β signaling responses in ovarian cancer22
Connexin32 gap junction channels deliver miR155-3p to mediate pyroptosis in renal ischemia-reperfusion injury22
Transfer of cGAMP from neuron to microglia activates microglial type I interferon responses after subarachnoid hemorrhage22
Correction to: Anti-Warburg effect by targeting HRD1-PFKP pathway may inhibit breast cancer progression22
Correction: Adiponectin affects the migration ability of bone marrow-derived mesenchymal stem cells via the regulation of hypoxia inducible factor 1α22
Local GHR roles in regulation of mitochondrial function through mitochondrial biogenesis during myoblast differentiation22
NCAM1-SHIP2 axis upon recognizing microbes inhibits the expressions of inflammatory factors through P38-H3K4me and P38-NF-κB pathways in oyster22
Correction: GPR65 inhibits human trophoblast cell adhesion through upregulation of MYLK and downregulation of fibronectin via cAMP-ERK signaling in a low pH environment22
The role of circRNAs in resistance to doxorubicin22
Correction: Diverse roles of SARS-CoV-2 spike and nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirin21
Correction to: A comprehensive review about immune responses and exhaustion during coronavirus disease (COVID-19)21
Cadmium exposure triggers alveolar epithelial cell pyroptosis by inducing mitochondrial oxidative stress and activating the cGAS-STING pathway21
Small extracellular vesicles: from mediating cancer cell metastasis to therapeutic value in pancreatic cancer21
miR-23b-3p, miR-126-3p and GAS5 delivered by extracellular vesicles inhibit breast cancer xenografts in zebrafish21
Cancer combination therapies by angiogenesis inhibitors; a comprehensive review21
Oligodendroglia-derived extracellular vesicles activate autophagy via LC3B/BAG3 to protect against oxidative stress with an enhanced effect for HSPB8 enriched vesicles21
miR-574-5p in epigenetic regulation and Toll-like receptor signaling21
Ubiquitin-specific protease: an emerging key player in cardiomyopathy21
Targeting uric acid: a promising intervention against oxidative stress and neuroinflammation in neurodegenerative diseases21
Adiponectin affects the migration ability of bone marrow-derived mesenchymal stem cells via the regulation of hypoxia inducible factor 1α20
Mechanosensitive channel of large conductance enhances the mechanical stretching-induced upregulation of glycolysis and oxidative metabolism in Schwann cells20
Concomitant targeting of FLT3 and SPHK1 exerts synergistic cytotoxicity in FLT3-ITD+ acute myeloid leukemia by inhibiting β-catenin activity via the PP2A-GSK3β axis20
Mesenchymal stromal cell-associated migrasomes: a new source of chemoattractant for cells of hematopoietic origin20
Correction to: Aiduqing formula inhibits breast cancer metastasis by suppressing TAM/CXCL1-induced Treg differentiation and infiltration20
The deubiquitinase EIF3H promotes hepatocellular carcinoma progression by stabilizing OGT and inhibiting ferroptosis20
CD146+CAFs promote progression of endometrial cancer by inducing angiogenesis and vasculogenic mimicry via IL-10/JAK1/STAT3 pathway20
Endothelial cell-derived extracellular vesicles modulate the therapeutic efficacy of mesenchymal stem cells through IDH2/TET pathway in ARDS19
CircRNAs: versatile players and new targets in organ fibrosis19
Cellular dynamics of EMT: lessons from live in vivo imaging of embryonic development19
IL13Rα2 as a crucial receptor for Chi3l1 in osteoclast differentiation and bone resorption through the MAPK/AKT pathway19
Extracellular vesicles from maternal uterine cells exposed to risk factors cause fetal inflammatory response19
Interactions among mTORC, AMPK and SIRT: a computational model for cell energy balance and metabolism19
A novel approach to alleviate acetaminophen-induced hepatotoxicity with hybrid balloon flower root-derived exosome-like nanoparticles (BDEs) with silymarin via inhibition of hepatocyte MAPK pathway an19
The scaffold protein AXIN1: gene ontology, signal network, and physiological function19
JMJD3: a critical epigenetic regulator in stem cell fate19
RNA N6-methyladenosine modification in female reproductive biology and pathophysiology18
Clinical features, plasma neurotransmitter levels and plasma neurohormone levels among patients with early-stage Parkinson’s disease with sleep disorders18
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma18
Interleukin-4 from curcumin-activated OECs emerges as a central modulator for increasing M2 polarization of microglia/macrophage in OEC anti-inflammatory activity for functional repair of spinal cord 18
ecRESCUE: a novel ecDHFR-regulated RESCUE system with reduced RNA off-targeting activity18
The destruction of mucosal barriers, epithelial remodeling, and impaired mucociliary clearance: possible pathogenic mechanisms of Pseudomonas aeruginosa and Staphylococcus aureus in chronic rhinosinus18
Polyploidy and mTOR signaling: a possible molecular link18
Novel roles of PIWI proteins and PIWI-interacting RNAs in human health and diseases18
Recent advances in the roles of exosomal microRNAs (exomiRs) in hematologic neoplasms: pathogenesis, diagnosis, and treatment18
Methylation as a key regulator of Tau aggregation and neuronal health in Alzheimer’s disease18
Salidroside attenuates HALI via IL-17A-mediated ferroptosis of alveolar epithelial cells by regulating Act1-TRAF6-p38 MAPK pathway18
New insights into the regulation of METTL3 and its role in tumors18
The role of MSCs and CAR-MSCs in cellular immunotherapy18
Fusobacterium nucleatum triggers proinflammatory cell death via Z-DNA binding protein 1 in apical periodontitis18
Mitochondrial DNA leakage induces odontoblast inflammation via the cGAS-STING pathway18
On the roles of intrinsically disordered proteins and regions in cell communication and signaling17
Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome17
Emerging roles of lactate in acute and chronic inflammation17
Cystathionine gamma-lyase (Cth) induces efferocytosis in macrophages via ERK1/2 to modulate intestinal barrier repair17
Extracellular vesicle-cell adhesion molecules in tumours: biofunctions and clinical applications17
Characterization of gastric cancer-stimulated signaling pathways and function of CTGF in cancer-associated fibroblasts17
The role of lactate in cardiovascular diseases17
Mesenchymal stem cells protect against TBI-induced pyroptosis in vivo and in vitro through TSG-616
The inducible role of autophagy in cell death: emerging evidence and future perspectives16
Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?16
Strategies for labelling of exogenous and endogenous extracellular vesicles and their application for in vitro and in vivo functional studies16
25KDa branched polyethylenimine increases interferon-γ production in natural killer cells via improving translation efficiency16
Impairments of GABAergic transmission in hippocampus mediate increased susceptibility of epilepsy in the early stage of Alzheimer’s disease16
Helicobacter pylori disrupts gastric mucosal homeostasis by stimulating macrophages to secrete CCL316
Characterization of the skin keloid microenvironment16
Synergism of non-thermal plasma and low concentration RSL3 triggers ferroptosis via promoting xCT lysosomal degradation through ROS/AMPK/mTOR axis in lung cancer cells16
Proximal tubule-derived exosomes contribute to mesangial cell injury in diabetic nephropathy via miR-92a-1-5p transfer16
Plant-derived extracellular vesicles: a novel nanomedicine approach with advantages and challenges16
LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration16
Novel dual-targeting c-Myc inhibitor D347-2761 represses myeloma growth via blocking c-Myc/Max heterodimerization and disturbing its stability16
Snail mediates GDF-8-stimulated human extravillous trophoblast cell invasion by upregulating MMP2 expression16
A positive feedback between PDIA3P1 and OCT4 promotes the cancer stem cell properties of esophageal squamous cell carcinoma15
RNF173 suppresses RAF/MEK/ERK signaling to regulate invasion and metastasis via GRB2 ubiquitination in Hepatocellular Carcinoma15
TMEM160 promotes tumor immune evasion and radiotherapy resistance via PD-L1 binding in colorectal cancer15
Role of STING in the treatment of non-small cell lung cancer15
The dual role of microRNA (miR)-20b in cancers: Friend or foe?15
Cancer derived exosomes induce macrophages immunosuppressive polarization to promote bladder cancer progression15
Ferroptosis: a promising candidate for exosome-mediated regulation in different diseases15
Misfolding and aggregation in neurodegenerative diseases: protein quality control machinery as potential therapeutic clearance pathways15
Mechanisms underlying linear ubiquitination and implications in tumorigenesis and drug discovery15
Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B15
Endoplasmic reticulum stress targeted therapy for breast cancer15
A rare olive compound oleacein functions as a TrkB agonist and mitigates neuroinflammation both in vitro and in vivo15
RU.521 mitigates subarachnoid hemorrhage-induced brain injury via regulating microglial polarization and neuroinflammation mediated by the cGAS/STING/NF-κB pathway15
STAT3 blockade ameliorates LPS-induced kidney injury through macrophage-driven inflammation15
How vascular smooth muscle cell phenotype switching contributes to vascular disease15
A slow-releasing donor of hydrogen sulfide inhibits neuronal cell death via anti-PANoptosis in rats with spinal cord ischemia‒reperfusion injury15
SARS-CoV-2 S protein activates NLRP3 inflammasome and deregulates coagulation factors in endothelial and immune cells15
New immunotherapy approaches for colorectal cancer: focusing on CAR-T cell, BiTE, and oncolytic viruses15
Diverse functions and pathogenetic role of Crumbs in retinopathy15
The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor15
Follicular fluid-derived exosomal miR-143-3p/miR-155-5p regulate follicular dysplasia by modulating glycolysis in granulosa cells in polycystic ovary syndrome15
Adipocyte derived exosomes promote cell invasion and challenge paclitaxel efficacy in ovarian cancer15
The crosstalk between copper-induced oxidative stress and cuproptosis: a novel potential anticancer paradigm15
Regulation of CD73 on NAD metabolism: Unravelling the interplay between tumour immunity and tumour metabolism15
Crosstalk with renal proximal tubule cells drives acidosis-induced inflammatory response and dedifferentiation of fibroblasts via p38-singaling14
IGFBP7 is a key component of the senescence-associated secretory phenotype (SASP) that induces senescence in healthy cells by modulating the insulin, IGF, and activin A pathways14
Deubiquitinating enzymes: potential regulators of the tumor microenvironment and implications for immune evasion14
Calpain-1 weakens the nuclear envelope and promotes the release of neutrophil extracellular traps14
The impact of erythroblast enucleation efficiency on the severity of anemia in patients with myelodysplastic syndrome14
Role of the Notch signaling pathway in porcine oocyte maturation14
Novel Ser74 of NF-κB/IκBα phosphorylated by MAPK/ERK regulates temperature adaptation in oysters14
Loss of mitochondrial Ca2+ response and CaMKII/ERK activation by LRRK2R1441G mutation correlate with impaired depolarization-induced mitophagy14
BI-2865, a pan-KRAS inhibitor, reverses the P-glycoprotein induced multidrug resistance in vitro and in vivo14
PLZF-expressing CD4+ T cells promote tissue-resident memory T cells in breaking immune tolerance in allergic asthma via IL-15/IL-15Rα signaling14
Paxillin participates in the sphingosylphosphorylcholine-induced abnormal contraction of vascular smooth muscle by regulating Rho-kinase activation14
MyD88 protein destabilization mitigates NF-κB-dependent protection against macrophage apoptosis14
Endogenous estrogen metabolites as oxidative stress mediators and endometrial cancer biomarkers14
Phosphoproteomics identifies determinants of PAK inhibitor sensitivity in leukaemia cells14
Biomechanics of circulating cellular and subcellular bioparticles: beyond separation14
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