OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Proteomics is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
An overview of multiplexed analyses of CAR T-cell therapies: insights and potential	67
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	46
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	43
Proteomic profiling and network biology of colorectal cancer liver metastasis	38
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	37
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	30
Proteomics in support of immunotherapy: contribution to model-based precision medicine	30
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	30
The role of proteomics in the multiplexed analysis of gene alterations in human cancer	29
Oncoproteomic profiling of AML: moving beyond genomics	29
Omics and rare diseases: challenges, applications, and future perspectives	27
The method developer’s guide to oligonucleotide design	25
Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice	25
Protein lysine acetylation and its role in different human pathologies: a proteomic approach	23
Positional proteomics: is the technology ready to study clinical cohorts?	21
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	19
Mapping the human brain proteome: opportunities, challenges, and clinical potential	19
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	19
Chondrocyte protein co-synthesis network analysis links ECM mechanosensing to metabolic adaptation in osteoarthritis	19
An overview of lipidomics utilizing cadaver derived biological samples	18
Proteomic tools to study phosphorylation of intrinsically disordered proteins	18
Utilizing databases for astrocyte secretome research	18
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	16
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	14
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	14

Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	14
Recent advances in mass spectrometry for the detection of doping	12
A Galaxy of informatics resources for MS-based proteomics	12
Replication of single-cell proteomics data reveals important computational challenges	11
Role of structural disorder in the multi-functionality of flavivirus proteins	11
Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	11
Proteomic interrogation of the human olfactory system: the road ahead	10
Analyzing the glial proteome in Alzheimer’s disease	10
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	10
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	9
Advances in the proteomic profiling of the matrisome and adhesome	9
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	9
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	8
How to maximize power for differential expression analysis in discovery omics through experimental design	8
Tackling reproducibility: lessons for the proteomics community	7
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	7
Glycosylation in cancer as a source of biomarkers	7
Advances in the clinical use of metaproteomics	7
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	7
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	7