OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Proteomics is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
An overview of multiplexed analyses of CAR T-cell therapies: insights and potential	68
The path to anti-vector vaccines: current advances and limitations in proteomics and bioinformatics	55
Proteomic insights into the extracellular matrix: a focus on proteoforms and their implications in health and disease	46
How can proteomics help solve the lack of biomarkers to aid in the early diagnosis of motor neuron disease (MND)?	39
Proteomic profiling and network biology of colorectal cancer liver metastasis	33
Proteomics in support of immunotherapy: contribution to model-based precision medicine	32
Cutaneous leishmaniasis: multiomics approaches to unravel the role of immune cells checkpoints	31
The interdependence of machine learning and LC-MS approaches for an unbiased understanding of the cellular immunopeptidome	31
Oncoproteomic profiling of AML: moving beyond genomics	29
The role of proteomics in the multiplexed analysis of gene alterations in human cancer	27
Omics and rare diseases: challenges, applications, and future perspectives	26
Breast cancer glycan biomarkers: their link to tumour cell metabolism and their perspectives in clinical practice	22
Positional proteomics: is the technology ready to study clinical cohorts?	21
LC-MS/MS: A sensitive and selective analytical technique to detect COVID-19 protein biomarkers in the early disease stage	20
Mapping the human brain proteome: opportunities, challenges, and clinical potential	20
The method developer’s guide to oligonucleotide design	20
A computational method for the prediction and functional analysis of potential Mycobacterium tuberculosis adhesin-related proteins	20
Protein lysine acetylation and its role in different human pathologies: a proteomic approach	20
Utilizing databases for astrocyte secretome research	18
Proteomic tools to study phosphorylation of intrinsically disordered proteins	17
Optimization of glycopeptide enrichment techniques for the identification of clinical biomarkers	17
Advancing kidney transplant outcomes: the role of urinary proteomics in graft function monitoring and rejection detection	15
Proteogenomic profiling of acute myeloid leukemia to identify therapeutic targets	15
Recent advances in mass spectrometry for the detection of doping	13
Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology	13

Unravelling disease complexity: integrative analysis of multi-omic data in clinical research	12
Replication of single-cell proteomics data reveals important computational challenges	11
Role of structural disorder in the multi-functionality of flavivirus proteins	11
Proteomic profiling of cerebrospinal fluid reveals pathophysiology changes and diversity of treatment response in pediatric streptococcus pneumoniae meningitis	9
T cell population size control by coronin 1 uncovered: from a spot identified by two-dimensional gel electrophoresis to quantitative proteomics	9
A Galaxy of informatics resources for MS-based proteomics	9
Analyzing the glial proteome in Alzheimer’s disease	9
Extracellular vesicle proteomics in brain solid tumors: future strategy for personalized medicine	8
Integrated metabolomics and proteomics analysis of plasma lipid metabolism in Parkinson’s disease	8
Salivary metabolomics in early detection of oral squamous cell carcinoma – a meta-analysis	8
Advances in the proteomic profiling of the matrisome and adhesome	8
Proteomic interrogation of the human olfactory system: the road ahead	8
The use of urine peptidomics to define dietary gluten peptides from patients with celiac disease and the clinical relevance	8
Rebellion of the deregulated regulators: What is the clinical relevance of studying intrinsically disordered proteins?	8
How to maximize power for differential expression analysis in discovery omics through experimental design	7
Revisiting the antigen markers of vector-borne parasitic diseases identified by immunomics: identification and application to disease control	6
Advances in the clinical use of metaproteomics	6
Glycosylation in cancer as a source of biomarkers	6
The evolution of analytical techniques for multiplex analysis of protein biomarkers	6
Tackling reproducibility: lessons for the proteomics community	6