OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Translational Medicine is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma	213
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	206
Magnetique: an interactive web application to explore transcriptome signatures of heart failure	202
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	178
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	175
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	173
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	172
Development and validation of new screening tool for predicting dementia risk in community-dwelling older Japanese adults	150
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation	144
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	138
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	117
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	116
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	114
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial	112
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	112
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer	109
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification	106
What can the neurological manifestations of COVID-19 tell us: a meta-analysis	105
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	105
VLCKD: a real time safety study in obesity	103
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	101
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	101
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils	101
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation	99
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling	98

High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10	96
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages	96
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	96
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study	93
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients	92
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	90
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	89
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia	88
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma	87
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers	86
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice	85
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics	84
Precision information extraction for rare disease epidemiology at scale	83
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics	81
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1	79
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition	76
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis	75
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma	74
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis	74
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	73
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	73
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases	73
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	72
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy	72
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance	71
Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control	70
SRSF9 promotes colorectal cancer progression via stabilizing DSN1 mRNA in an m6A-related manner	69
Dexmedetomidine inhibits mitochondria damage and apoptosis of enteric glial cells in experimental intestinal ischemia/reperfusion injury via SIRT3-dependent PINK1/HDAC3/p53 pathway	69
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation	68
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma	68
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study	67
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images	67
Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models	67
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway	65
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma	65
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway	64
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis	64
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati	64
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study	63
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study	63