OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Translational Medicine is 60. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Heparin-binding growth factor (HDGF) drives radioresistance in breast cancer by activating the STAT3 signaling pathway	302
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN	198
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma	187
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	182
Magnetique: an interactive web application to explore transcriptome signatures of heart failure	173
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP10	168
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	161
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	154
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	153
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	135
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	127
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme	117
Development and validation of new screening tool for predicting dementia risk in community-dwelling older Japanese adults	110
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study	108
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation	108
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care	107
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden	100
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	99
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	98
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer	95
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	95
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	94
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis	92
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity	92
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	91

Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	90
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	89
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	88
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation	87
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	85
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	84
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	84
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1	82
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	82
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	79
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	79
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation	77
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia	77
What can the neurological manifestations of COVID-19 tell us: a meta-analysis	77
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study	75
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma	75
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease	71
Precision information extraction for rare disease epidemiology at scale	71
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation	70
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers	70
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction	69
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv	69
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice	68
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology	67
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics	67
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling	65
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer	65
Physiological assessment of orthostatic intolerance in chronic fatigue syndrome	65
Global research trends on the links between the gut microbiome and cancer: a visualization analysis	65
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer	63
Red blood cell-derived arginase release in hemolytic uremic syndrome	63
Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control	62
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study	62
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation	61
Exploring TNFR1: from discovery to targeted therapy development	60
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway	60