OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Translational Medicine is 58. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Establishment and validation of predictive model of ARDS in critically ill patients	269
The role of laminins in cancer pathobiology: a comprehensive review	185
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	172
Endogenous peptide CBDP1 inhibits clear cell renal cell carcinoma progression by targeting USP5/YTHDF2/TRPM5 axis	163
Oxidative stress and retinopathy: evidence from epidemiological studies	163
Deciphering the cellular and molecular landscape of pulmonary fibrosis through single-cell sequencing and machine learning	160
Complex regulation of cardiac fibrosis: insights from immune cells and signaling pathways	153
Inhibition of the FEN1-PBX1 axis elicits cellular senescence in breast cancer via the increased intracellular reactive oxygen species levels	152
The effectiveness and safety of RC48 alone or in combination with PD-1 inhibitors for locally advanced or metastatic urothelial carcinoma: a multicenter, real-world study	126
FlaA N/C attenuates radiation-induced lung injury by promoting NAIP/NLRC4/ASC inflammasome autophagy and inhibiting pyroptosis	120
Differential T-cell profiles determined by Hepatitis B surface antigen decrease among people with Human Immunodeficiency Virus /Hepatitis B Virus coinfection on treatment	112
Ferrostatin-1 reduces the inflammatory response of rheumatoid arthritis by decreasing the antigen presenting function of fibroblast-like synoviocytes	103
Prognostic implications and characterization of tumor-associated tertiary lymphoid structures genes in pancreatic cancer	101
Biomarker identification for Alzheimer’s disease through integration of comprehensive Mendelian randomization and proteomics data	101
A rapid ecologic analysis, confirmed by a case–control study, identifies class I HLA alleles correlated to the risk of COVID-19	99
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	98
Super-enhancer-hijacking RBBP7 potentiates metastasis and stemness of breast cancer via recruiting NuRD complex subunit LSD1	94
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model	92
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer	89
Effects of sevoflurane on lung epithelial permeability in experimental models of acute respiratory distress syndrome	89
Plasma proteome of Long-COVID patients indicates HIF-mediated vasculo-proliferative disease with impact on brain and heart function	88
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma	87
Colonization of fecal microbiota from patients with neonatal necrotizing enterocolitis exacerbates intestinal injury in germfree mice subjected to necrotizing enterocolitis-induction protocol via alte	86
Exosome-transported circ_0061407 and circ_0008103 play a tumour-repressive role and show diagnostic value in non-small-cell lung cancer	84
Bifidobacterium adolescentis-derived hypaphorine alleviates acetaminophen hepatotoxicity by promoting hepatic Cry1 expression	83

Physiological assessment of orthostatic intolerance in chronic fatigue syndrome	83
HER3 receptor and its role in the therapeutic management of metastatic breast cancer	82
Potential roles of the interactions between gut microbiota and metabolites in LPS-induced intrauterine inflammation (IUI) and associated preterm birth (PTB)	79
The appropriate division of data in training of computers to predict physicians’ decision on blood transfusions: a reply to Dr. Sander de Bruyne	79
Analysis of changes in microbiome compositions related to the prognosis of colorectal cancer patients based on tissue-derived 16S rRNA sequences	79
Adapting modeling and simulation credibility standards to computational systems biology	78
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics	77
Identification and analysis of mitochondria-related key genes of heart failure	77
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke	76
Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease	73
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	72
Staphylococcus aureus induces mitophagy via the HDAC11/IL10 pathway to sustain intracellular survival	72
A comprehensive transcriptional reference for severity and progression in spinal cord injury reveals novel translational biomarker genes	71
AC099850.3 promotes HBV-HCC cell proliferation and invasion through regulating CD276: a novel strategy for sorafenib and immune checkpoint combination therapy	70
Antibody targeting of anaerobic bacteria warms cold tumors and improves the abscopal effect of radiotherapy	70
Elevated CHCHD4 orchestrates mitochondrial oxidative phosphorylation to disturb hypoxic pulmonary hypertension	69
miR-1297 sensitizes glioma cells to temozolomide (TMZ) treatment through targeting adrenomedullin (ADM)	68
The Glioma-IRE project − Molecular profiling in patients with glioma: steps toward an individualized diagnostic and therapeutic approach	66
Comparison of clinical outcomes of frozen-thawed D5 and D6 blastocysts undergoing preimplantation genetic testing	65
Standardizing digital biobanks: integrating imaging, genomic, and clinical data for precision medicine	65
Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models	64
Tanshinone IIA ameliorates Aβ transendothelial transportation through SIRT1-mediated endoplasmic reticulum stress	64
Membrane-associated RING-CH protein (MARCH8) is a novel glycolysis repressor targeted by miR-32 in colorectal cancer	63
Downregulation of mitochondrial complex I induces ROS production in colorectal cancer subtypes that differently controls migration	63
Mitochondrion-targeted carboxymethyl chitosan hybrid nanoparticles loaded with Coenzyme Q10 protect cardiac grafts against cold ischaemia‒reperfusion injury in heart transplantation	63
HBO treatment enhances motor function and modulates pain development after sciatic nerve injury via protection the mitochondrial function	63
Extracellular vesicles at the crossroad between cancer progression and immunotherapy: focus on dendritic cells	62
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes	61
DKK1 loss promotes endometrial fibrosis via autophagy and exosome-mediated macrophage-to-myofibroblast transition	61
Mitochondrial dysfunction gene expression, DNA methylation, and inflammatory cytokines interaction activate Alzheimer’s disease: a multi-omics Mendelian randomization study	60
Type 2 diabetic mellitus related osteoporosis: focusing on ferroptosis	60
SIRT6 prevent chronic cerebral hypoperfusion induced cognitive impairment by remodeling mitochondrial dynamics in a STAT5-PGAM5-Drp1 dependent manner	59
Tumor-suppressive MEG3 induces microRNA-493-5p expression to reduce arabinocytosine chemoresistance of acute myeloid leukemia cells by downregulating the METTL3/MYC axis	58
Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers	58
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	58
Emerging role of human microbiome in cancer development and response to therapy: special focus on intestinal microflora	58