OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Translational Medicine is 67. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Comprehensive analysis of microglia gene and subpathway signatures for glioma prognosis and drug screening: linking microglia to glioma	254
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway	229
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology	216
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis	208
The PDE4 inhibitor tanimilast shows distinct immunomodulatory properties associated with a type 2 endotype and CD141 upregulation	187
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv	181
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers	175
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults	169
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers	146
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses	134
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis	133
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism	133
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine	128
Global research trends on the links between the gut microbiome and cancer: a visualization analysis	126
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN	126
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance	122
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study	121
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease	120
Membrane progesterone receptor α (mPRα) enhances hypoxia-induced vascular endothelial growth factor secretion and angiogenesis in lung adenocarcinoma through STAT3 signaling	118
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer	117
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma	116
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance	114
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable	113
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury	107
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul	107

Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes	105
Precision information extraction for rare disease epidemiology at scale	104
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis	103
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation	101
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology	100
LINC00491 promotes cell growth and metastasis through miR-324-5p/ROCK1 in liver cancer	98
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy	98
Heat shock protein A4 ablation leads to skeletal muscle myopathy associated with dysregulated autophagy and induced apoptosis	98
Detecting prognostic biomarkers of breast cancer by regularized Cox proportional hazards models	98
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis	96
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway	95
Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia	92
A call to reignite the revolutionary spirit of scientific discovery	90
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction	88
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation	87
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma	86
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis	85
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients	84
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification	84
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma	84
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway	84
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation	83
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis	82
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions	82
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies	81
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study	79
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati	78
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer	78
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia	78
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients	77
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation	76
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma	75
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer	75
Incidence and immunomic features of apyretic COVID-19 in patients affected by solid tumors: a prospective cohort study	74
Red blood cell-derived arginase release in hemolytic uremic syndrome	72
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer	72
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model	69
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment	69
Establishment and validation of predictive model of ARDS in critically ill patients	69
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer	68
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study	68
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles	67
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial	67
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation	67
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway	67
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients	67