Journal of Translational Medicine

Papers
(The TQCC of Journal of Translational Medicine is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)
ArticleCitations
A critical evaluation of berberine in NAFLD management: recommendations for improved research methodology348
Link of TMPRSS2 expression with tumor immunogenicity and response to immune checkpoint inhibitors in cancers280
Analysis of thyroid carcinoma composition and spatial architecture in the progression of dedifferentiation, lymphatic metastasis, and gastric metastasis234
KAT2B regulates estradiol synthesis via H3K27ac/PPARα in granulosa cells of PCOS patients186
Spastin accumulation and motor neuron defects caused by a novel SPAST splice site mutation181
A call to reignite the revolutionary spirit of scientific discovery178
Current perspectives in obesity management: unraveling the impact of different therapy approach in real life obesity care171
Myomedin variants developed for in vitro PD-L1 diagnostics in tissue samples of non-small cell lung carcinoma patients167
Associations of types of grains and lifestyle with all-cause mortality among Chinese adults aged 65 years or older: a prospective cohort study166
CircNDC80 promotes glioblastoma multiforme tumorigenesis via the miR-139-5p/ECE1 pathway164
Limosilactobacillus reuteri prevents progression of ankylosing spondylitis in mice by restoring gut microbiota-metabolism homeostasis160
Fully volumetric body composition analysis for prognostic overall survival stratification in melanoma patients151
Precision information extraction for rare disease epidemiology at scale150
MicroRNA-24-3p targeting Top1 in perirenal fat is involved in circulating inflammation and high cardiovascular disease risk in patients with primary aldosteronism149
Correction: NUCB2/Nesfatin-1 drives breast cancer metastasis through the up-regulation of cholesterol synthesis via the mTORC1 pathway146
From sensitivity to public health: integrating cfMeDIP-seq into early breast cancer detection strategies146
Targeting lactylation in a novel metabolic-epigenetic-inflammatory axis mitigates inflammation and promotes healing following corneal injury140
A 3-tier information fusioned framework featuring explainable deep active optimized CRNet for accurate heart disease prediction137
Correction to: Augmentation of tumor expression of HLADR, CXCL9, and CXCL10 may improve olfactory neuroblastoma immunotherapeutic responses134
Correction: Fluorinated hydroxyapatite conditions a favorable osteo-immune microenvironment via triggering metabolic shift from glycolysis to oxidative phosphorylation132
Ketoglutaric acid can reprogram the immunophenotype of triple-negative breast cancer after radiotherapy and improve the therapeutic effect of anti-PD-L1130
Silencing PinX1 enhances radiosensitivity and antitumor-immunity of radiotherapy in non-small cell lung cancer129
Identification of comutation in signaling pathways to predict the clinical outcomes of immunotherapy129
Assessing the causal effect of genetically predicted metabolites and metabolic pathways on stroke128
A bispecific antibody AP203 targeting PD-L1 and CD137 exerts potent antitumor activity without toxicity125
Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classification124
Polygenic risk score of metabolic dysfunction-associated steatotic liver disease amplifies the health impact on severe liver disease and metabolism-related outcomes123
Validity between dual-energy x-ray absorptiometry and bioelectrical impedance for segmental fat analysis and a novel low-cost model developed using anthropometry in young adults119
Identification of epigenetic silencing of the SFRP2 gene in colorectal cancer as a clinical biomarker and molecular significance118
Biological tissue engineering for Fontan failure using decellularized extracellular matrix: a systematic review117
Dissecting transcription of the 8q24-MYC locus in prostate cancer recognizes the equilibration between androgen receptor direct and indirect dual-functions117
Artemisinin conferred cytoprotection to human retinal pigment epithelial cells exposed to amiodarone-induced oxidative insult by activating the CaMKK2/AMPK/Nrf2 pathway116
m6A RNA modification and its emerging roles in diseases: recent advances and therapeutic implications112
Macrophages as determinants and regulators of systemic sclerosis-related interstitial lung disease112
Computational pathology approach for assessment of prognosis and immunotherapy response in pan-gastrointestinal cancer111
A novel model for predicting prolonged stay of patients with type-2 diabetes mellitus: a 13-year (2010–2022) multicenter retrospective case–control study109
Engineered macrophage membrane-coated dihydroartemisinin nanoparticles with enhanced CCR2 expression improved symptoms in MRL/LPR mice by metabolic reprogramming of proinflammatory macrophages108
Prognosis-Related Nutritional Score for Cancer Patients (PRNS): a clinical nutritional score derived from a retrospective cohort study108
Alterations in whole muscle quality and physiological cross-sectional area measured with quantitative MRI following ACL injury108
Magnetique: an interactive web application to explore transcriptome signatures of heart failure106
Genetic pleiotropy underlying obesity and autoimmune disorders: a large-scale cross-trait gwas analysis in European ancestry populations106
Identification of memory B-cell-associated miRNA signature to establish a prognostic model in gastric adenocarcinoma106
Clinical impact of volume of disease and time of metastatic disease presentation on patients receiving enzalutamide or abiraterone acetate plus prednisone as first-line therapy for metastatic castrati104
Unlocking the potential of EphA2 with precision-guided cancer therapy: bicycle drug conjugates103
Radiogenomic MRI biomarkers for noninvasive prediction of GPC3 expression and tumor microenvironment in hepatocellular carcinoma103
B cell pathways implicate shared genetic architecture between schizophrenia and immune-mediated diseases103
Maternal DNA methylation signatures of gestational diabetes across all stages of pregnancy102
Pretreatment of UC-MSCs with IFN-α2 improves treatment of liver fibrosis by recruiting neutrophils101
Cell–cell communications shape tumor microenvironment and predict clinical outcomes in clear cell renal carcinoma101
Deep learning-based 3D leukocyte differentiation using label-free higher harmonic generation microscopy101
Lactylation of β-catenin promotes non-small cell lung cancer by inhibiting ferroptosis through TCF4-mediated GPX4 transcription100
USP5 in cancer: a therapeutic window into metabolism and drug resistance99
Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv97
Inhibition of DDR1 potentiates carbon ion radiotherapy by promoting ferroptosis and immunogenic death in head and neck squamous cell carcinoma96
Association of vitamin B2 intake with cognitive performance in older adults: a cross-sectional study96
Elevated NGF provokes decidual lipid peroxidation and promotes preterm birth in mice96
Hyperuricemia suppresses lumican, exacerbating adverse remodeling after myocardial infarction by promoting fibroblast phenotype transition95
Advances in gene therapy for mitochondrial genetic disorders: current status and clinical implementation challenges95
Peroxynitrite regulates ER stress-mediated Ca2+ flux to mitochondria characterizing cardiac microvascular ischemia–reperfusion injury associated with hyperhomocysteinemia94
Establishment and validation of predictive model of ARDS in critically ill patients93
Combination of mutations in genes controlling DNA repair and high mutational load plays a prognostic role in pancreatic ductal adenocarcinoma (PDAC): a retrospective real-life study in Sardinian popul92
Weighted gene coexpression network analysis and machine learning reveal oncogenome associated microbiome plays an important role in tumor immunity and prognosis in pan-cancer91
Molecular imaging in gastric cancer: state-of-the-art techniques and emerging opportunities91
Effect of perioperative probiotic intervention on postoperative cognitive dysfunction in elderly patients: a randomized double- blinded and placebo-controlled trial90
NCAPG promotes the proliferation of hepatocellular carcinoma through the CKII-dependent regulation of PTEN90
Deciphering the generation of heterogeneity in esophageal squamous cell carcinoma metastasis via single-cell multiomics analysis88
A novel deep learning-based algorithm combining histopathological features with tissue areas to predict colorectal cancer survival from whole-slide images88
Microplastics as an emerging driver of osteoarthritis: a translational synthesis of environmental exposure, patho-mechanisms, and public health implications88
Metabolomics approach reveals key plasma biomarkers in multiple myeloma for diagnosis, staging, and prognosis87
The CLIC1-PKM2 axis orchestrates glycolytic metabolism to accelerate gastric cancer progression86
Arginine-linked HPV-associated E7 displaying bacteria-derived outer membrane vesicles as a potent antigen-specific cancer vaccine86
The biological function of the N6-Methyladenosine reader YTHDC2 and its role in diseases86
Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain84
RAD21 regulation of the enhancer–promoter chromatin loop of RAD51 promotes PARPi resistance in ovarian cancer84
Vorinostat impairs the cancer-driving potential of leukemia-secreted extracellular vesicles83
Two-sample Mendelian Randomization to evaluate the causal relationship between inflammatory arthritis and female-specific cancers81
Chronic liver diseases aggravate radiation-induced intestinal injury through taurocholic acid dysregulation81
Dietary patterns, polygenic risk, and kidney cancer incidence: a UK Biobank cohort study77
Accumulated β-catenin is associated with human atrial fibrosis and atrial fibrillation77
Integrated screening for small molecules interfering with PKM2: a drug repurposing strategy against glioblastoma76
CircGLIS3 promotes gastric cancer progression by regulating the miR-1343-3p/PGK1 pathway and inhibiting vimentin phosphorylation75
USP5-Mediated PD-L1 deubiquitination regulates immunotherapy efficacy in melanoma75
An imaging biomarker to detect non-glucogenic shift in brain energy metabolism in Alzheimer’s disease75
Identification of novel first-trimester serum biomarkers for early prediction of preeclampsia75
High VSX1 expression promotes the aggressiveness of clear cell renal cell carcinoma by transcriptionally regulating FKBP1074
Unleashing endogenous regeneration by senolytics73
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment73
Functions and mechanisms of lncRNAs in immune escape and their application in immunotherapy for colorectal cancer73
Dual immunosuppression mechanism induced by PTP1B in colorectal cancer: upregulation of PD-L1 by FOXO1/miR-34C/c-MYC axis and inhibition of the infiltration of CD8(+) T cell by downregulating of CXCL172
Integrative multi-omics analysis unveils stemness-associated molecular subtypes in prostate cancer and pan-cancer: prognostic and therapeutic significance72
Immunogenicity of adalimumab in patients with noninfectious uveitis based on therapeutic drug monitoring72
Identification and validation of a prognostic signature of drug resistance and mitochondrial energy metabolism-related differentially expressed genes for breast cancer72
Multiomics prediction and immunogenic validation of personalized neoantigens in cholangiocarcinoma patients71
Pancreatic organoids and organoid-on-a-chip platforms: from disease modeling to precision therapy71
Translational potential of GMP-grade human umbilical cord-derived mesenchymal stem cells (UC-MSCs) in traumatic spinal cord injury: a preclinical study in rat71
Single-cell RNA sequencing reveals a B cell-related immunosuppressive landscape and a potential suppressor in hepatocellular carcinoma71
The innovative checkpoint inhibitors of lung adenocarcinoma, cg09897064 methylation and ZBP1 expression reduction, have implications for macrophage polarization and tumor growth in lung cancer70
The Swedish childhood tumor biobank: systematic collection and molecular characterization of all pediatric CNS and other solid tumors in Sweden70
Functional regulation of GlycoRNA and progress in malignant tumors70
Gender differences in eating habits and sports preferences across age groups: a cross-sectional study70
Neutrophils cultured ex vivo from CD34+ stem cells are immature and genetically tractable69
An Fgr kinase inhibitor attenuates sepsis-associated encephalopathy by ameliorating mitochondrial dysfunction, oxidative stress, and neuroinflammation via the SIRT1/PGC-1α signaling pathway68
Novel models by machine learning to predict prognosis of breast cancer brain metastases68
Peripheral nerve repair: innovations and future directions68
Lower airway transcriptome signatures in asthma: a newly described cytokine C10orf99 identification68
Knockdown of eIF3a alleviates pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition via TGFβ1/SMAD pathway67
Protectin conjugates in tissue regeneration 1 alleviates sepsis-induced acute lung injury by inhibiting ferroptosis67
Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology67
Effects of prebiotics and phytochemicals on serum trimethylamine N-oxide reduction and gut microbiota: a systematic review and meta-analysis67
Epithelial cell diversity and immune remodeling in bladder cancer progression: insights from single-cell transcriptomics66
C3+ cancer-associated fibroblasts promote tumor growth and therapeutic resistance in gastric cancer via activation of the NF-κB signaling pathway66
Immune-related lncRNAs signature and radiomics signature predict the prognosis and immune microenvironment of glioblastoma multiforme66
Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis65
Advancing polytrauma care: developing and validating machine learning models for early mortality prediction65
Discovery of novel JAK1 inhibitors through combining machine learning, structure-based pharmacophore modeling and bio-evaluation65
Emerging therapeutic strategies for unmet need in neovascular age-related macular degeneration65
Exploring TNFR1: from discovery to targeted therapy development65
Interferon lambda in anti-viral defense and cancer: dual roles, mechanism and therapeutic potential65
The interplay between driver mutation and oxidative stress in colorectal cancer: from pathogenesis to therapeutics64
Red blood cell-derived arginase release in hemolytic uremic syndrome64
An enhanced-permeability amphiphilic nanogel loaded with sulforaphane for synergistic anti-oxidative and anti-ferroptotic therapy of corneal alkali burn64
Deciphering USP8’s pivotal role in cancer: mechanisms, clinical insights and contrasts with its function in pituitary adenomas64
WGX50 mitigates doxorubicin-induced cardiotoxicity through inhibition of mitochondrial ROS and ferroptosis64
Targeting macrophages: a novel treatment strategy in solid tumors63
Removal of aging microenvironment of bone defects can effectively promote bone defect repair63
Lactate infusion elevates cardiac output through increased heart rate and decreased vascular resistance: a randomised, blinded, crossover trial in a healthy porcine model62
CX26 promotes pancreatic cancer progression by competitively inhibiting interaction of c-Myc with PSMD2 and enhancing c-Myc stability62
Targeting severe symptoms of early 2023-new outbreak of COVID-19 by classical drug dexamethasone: a potential fatality reducing agent62
Association of BMI, BMR, BSA, and body weight with psoriasis severity and treatment response: evidence from a real-world cohort62
RERE-AS1 enhances the effect of CDK4/6 inhibitor Ribociclib and suppresses malignant phenotype in breast cancer via MEK/ERK pathway61
Targeting CDH13 as a therapeutic strategy to mitigate pathological ocular angiogenesis61
Clinical trial landscape for periodontitis treatment: Trend analysis and future perspectives61
IL-17 + γδT cell: a new target in hyperbaric oxygen treatment reducing spinal cord injury61
Metabolic expression profiling analysis reveals pyruvate-mediated EPHB2 upregulation promotes lymphatic metastasis in head and neck squamous cell carcinomas61
The MAFG-AS1/G6PD axis reduces platinum sensitivity in colorectal cancer through pentose phosphate pathway activation60
Patient-derived scaffolds representing breast cancer microenvironments influence chemotherapy responses in adapted cancer cells consistent with clinical features60
USP51 promotes non-small cell lung carcinoma cell stemness by deubiquitinating TWIST160
N6-methyladenosine RNA modified BAIAP2L2 facilitates extracellular vesicles-mediated chemoresistance transmission in gastric cancer60
A genomic strategy for precision medicine in rare diseases: integrating customized algorithms into clinical practice60
The preprogrammed anti-inflammatory phenotypes of CD11chigh macrophages by Streptococcus pneumoniae aminopeptidase N safeguard from allergic asthma59
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer59
New insights from a systematic review and meta-analysis on the treatment of difficult-to-treat rheumatoid arthritis59
Polygenic risk of paclitaxel-induced peripheral neuropathy: a genome-wide association study58
IκBα kinase inhibitor BAY 11-7082 promotes anti-tumor effect in RAS-driven cancers58
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant58
Multiomics unravels the complexity of male obesity: a prospective observational study58
Efficacy of LNP@2DG-DON liposomal nanoparticles in tumor inhibition and immune activation58
The role and mechanism by which micropeptide WHPP promote refractory wound healing58
Computed tomography-detected extramural venous invasion-related gene signature: a potential negative biomarker of immune checkpoint inhibitor treatment in patients with gastric cancer58
Targeting GPA33 with CAR-macrophages: a novel immunotherapeutic approach for colorectal cancer58
Targeting cell membrane sphingolipids: a novel ceramide analog CeY-B1 inhibits migration and invasion in cervical cancer cells58
Sodium-myoinositol cotransporter-1 downstream of m6A methyltransferase WTAP exerts a potential carcinogenicity in diffuse large B-cell lymphoma progression58
Comparison of retinal degeneration treatment with four types of different mesenchymal stem cells, human induced pluripotent stem cells and RPE cells in a rat retinal degeneration model57
Targeting ubiquitin-specific protease 14 reduces metastatic potential and metabolic activity in cervical cancer via direct modulation of monocarboxylate transporter-457
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer57
Promoting the transition from pyroptosis to apoptosis in endothelial cells: a novel approach to alleviate methylglyoxal-induced vascular damage56
Truncated APC impairs innate immune response by targeting MAVS on mitochondria in colorectal cancer56
Fetal and obstetrics manifestations of mitochondrial diseases56
Comments on “Unleashing the therapeutic potential of tumor-draining lymph nodes: spotlight on bladder cancer”56
Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC56
Gut microbiota remodeling and sensory-emotional functional disruption in adolescents with bipolar depression56
FASN for diffuse malignant peritoneal mesothelioma: a prognostic biomarker after CRS+HIPEC and a therapeutic target55
Methylation regulatory networks in osteoarthritis: mechanisms and targeted therapies55
Comprehensive analysis of the interaction microbiome and prostate cancer: an initial exploration from multi-cohort metagenome and GWAS studies55
Landscape of molecular crosstalk between SARS-CoV-2 infection and cardiovascular diseases: emphasis on mitochondrial dysfunction and immune-inflammation55
Dermatological implications of alignment-based de-hosting and bioinformatics pipelines on shotgun microbiome analysis55
Sinensetin serves as an AMPK activator to inhibit RANKL-induced osteoclastogenesis via osteoclast cytoskeleton reorganization54
FOSL1 drives the malignant progression of pancreatic cancer cells by regulating cell stemness, metastasis and multidrug efflux system54
Tamoxifen exerts anti-peritoneal fibrosis effects by inhibiting H19-activated VEGFA transcription54
A partitioned polygenic risk score reveals distinct contributions to psoriasis clinical phenotypes across a multi-ethnic cohort54
MX1+ effector T cells hyperactivation at the maternal-fetal interface in unexplained recurrent pregnancy loss54
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements54
The APOE ε4 allele affects the survival of patients with Parkinson's disease independent of dementia54
KLRG1 silencing increases the efficacy of CAR NK cell therapy against colon cancer via SHP-2/ZAP-70/NF-κB signal pathway54
Exosomes derived from hypoxia-preconditioned M2 macrophages alleviate degeneration in knee osteoarthritis through the miR‑124‑3p/STAT3 axis54
COVPRIG robustly predicts the overall survival of IDH wild-type glioblastoma and highlights METTL1+ neural-progenitor-like tumor cell in driving unfavorable outcome54
High Hcy regulates fluid shear stress pathway activity through histone H3K79 homocysteinylation in hyperhomocysteinemia-related child hypertension53
Innate immune functions of bitter taste receptors across physiological systems53
Interrelationships and determinants of aging biomarkers in cord blood53
Current strategies employed in the manipulation of gene expression for clinical purposes53
Stargardt disease-associated in-frame ABCA4 exon 17 skipping results in significant ABCA4 function53
PUF, a biflavone monomer, triggers DNA damage through SLC25A15 downregulation and purine metabolic suppression in DLBCL53
Single-cell profiles reveal tumor cell heterogeneity and immunosuppressive microenvironment in Waldenström macroglobulinemia53
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study53
Fbxw7 suppresses carcinogenesis and stemness in triple-negative breast cancer through CHD4 degradation and Wnt/β-catenin pathway inhibition52
HPV status shapes T-cell immunoprofiles in oesophageal adenocarcinoma: high regulatory T cell infiltration predicts poor prognosis52
CD155 reprograms glycolysis via the YAP/TEAD1-GLUT1 axis to promote lung adenocarcinoma progression and M2 macrophage polarization: a metabolic-immune target visualized by 18F-FDG PET/CT52
Gut microbiome alterations and hepatic encephalopathy post-TIPS in liver cirrhosis patients52
Correction to: COSMIC‑based mutation database enhances identification efficiency of HLA‑I immunopeptidome52
Good practice in medicine and biology: scientific integrity needs global bioethics52
Tyrosine kinase signaling-independent MET-targeting with CAR-T cells52
Effect of vitamin D supplementation on skeletal muscle function and quality of life in patients with chronic intestinal failure: a randomized controlled trial52
Correction to: Combining functional and morphological retinal vascular characteristics achieves high-precision diagnosis of mild non-proliferative diabetic retinopathy52
METTL3-driven m6A modification promotes tumor progression and immune evasion in hypoxic pancreatic cancer by enhancing ADAM10-mediated MICA shedding51
Wnt/β-catenin signaling in the development and therapeutic resistance of non-small cell lung cancer51
The microtubule targeting agent ST-401 triggers cell death in interphase and prevents the formation of polyploid giant cancer cells51
Development and validation of radiopathomics models for predicting molecular subtypes and WHO grades in adult-type diffuse gliomas: a multicenter study51
GCN5L1-mediated TFAM acetylation at K76 participates in mitochondrial biogenesis in acute kidney injury51
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens51
Role of TLR7 expression in cancer: impact on immune activation and prognostic evaluation51
CircPRKCA facilitates esophageal squamous cell carcinoma metastasis via m5C-dependent CSF2 mRNA stabilization51
Function and mechanism of GBP1 in the development and progression of cervical cancer51
Does preeclampsia impact the gut microbiota of preterm offspring during early infancy?51
Discovery of a pyrano[2,3-b]pyridine derivative YX-2102 as a cannabinoid receptor 2 agonist for alleviating lung fibrosis50
Transformative advances in single-cell omics: a comprehensive review of foundation models, multimodal integration and computational ecosystems50
The oncogenic potential of SOX12: a comprehensive and perspective view50
Technological Vanguard: the outstanding performance of the LTY-CNN model for the early prediction of epileptic seizures50
Applications and potential mechanisms of transcranial magnetic stimulation in autism spectrum disorders50
Efficacy of MET-targeting CAR T cells against glioblastoma patient-derived xenograft models50
Mitochondrial transplantation: a promising strategy for treating degenerative joint diseases50
Enterococcus faecalis promotes the progression of colorectal cancer via its metabolite: biliverdin50
Integrative multi-omics analysis proposes a metabolic classification of gliomas: distinct metabolic states, immune infiltration, and prognosis50
METTL3-mediated HOTAIRM1 promotes vasculogenic mimicry icontributionsn glioma via regulating IGFBP2 expression50
Wnt5a augments intracellular free cholesterol levels and promotes castration resistance in prostate cancer50
NK cell infusion is well-tolerated and shows preliminary efficacy in patients with recurrent hepatocellular carcinoma post-liver transplantation : a phase I trial49
Recent advances in osteonecrosis of the femoral head: a focus on mesenchymal stem cells and adipocytes49
Microglial dysregulation and spatiotemporal dynamics of inflammation in multiple sclerosis white matter: an integrative transcriptomic analysis49
Increased nerve density adversely affects outcome in colorectal cancer and denervation suppresses tumor growth49
Metabolic vulnerability index and MetaboHealth score as risk factors for age-related macular degeneration in a large-scale prospective cohort49
IL1β+ macrophages promote intestinal fibrosis in Crohn’s disease by secreting AREG to activate PI16+ fibroblasts49
Strain-level characterization of bacterial pathogens using metagenomic sequencing for patients with pneumonia49
Blautia coccoides and its metabolic products enhance the efficacy of bladder cancer immunotherapy by promoting CD8+ T cell infiltration49
Low-intensity pulsed ultrasound for peripheral nerve regeneration: mechanobiological mechanisms and translational potential49
Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study49
CR1(+) tumor-associated macrophages orchestrate an immunosuppressive niche in hepatocellular carcinoma: a genetic and multi-omics dissection48
Meta-analysis of comparing CAR-T and bispecific antibody therapy in relapsed/refractory indolent B-cell non-Hodgkin’s lymphomas48
The STUB1-TPIT axis regulates the secretion of adrenocorticotrophic hormone in cushing disease48
CircSipa1l1 modulates melanoma cell differentiation by activating the IGF2BP1-ARHGDIB axis and ERK signaling pathway48
Increased circulating uric acid aggravates heart failure via impaired fatty acid metabolism48
Mesenchymal stem cells can prevent or promote the progression of colon cancer based on their timing of administration48
Targeting PRDX2 to inhibit tumor growth and metastasis in triple-negative breast cancer: the role of FN1 and the PI3K/AKT/SP1 pathway47
Robust SNP-based prediction of rheumatoid arthritis through machine-learning-optimized polygenic risk score47
PPARγ signalling pathway: molecular mechanisms and therapeutic potential in ligamentum flavum hypertrophy and lumbar spinal stenosis47
HERVs may perform as the initial trigger for acquired aplastic anemia47
Pivotal interplays between fecal metabolome and gut microbiome reveal functional signatures in cerebral ischemic stroke46
Fibrosis and bone marrow: understanding causation and pathobiology46
Genetic evidence of the causal relationship between chronic liver diseases and musculoskeletal disorders46
The role of PPP2R1A variants in gynecologic malignancies: a paradigm shift in immuno-oncology46
Epstein-Barr virus-coded miR-BART19-3p promotes proliferation of EBV-associated gastric cancer by inhibiting GADD45B46
HuR promotes castration-resistant prostate cancer progression by altering ERK5 activation via posttranscriptional regulation of BCAT146
The efficacy and safety of fecal microbiota transplantation in the treatment of sarcopenia: a retrospective study46
Novel hypoxia- and lactate metabolism-related molecular subtyping and prognostic signature for colorectal cancer46
MCT4: a key player influencing gastric cancer metastasis and participating in the regulation of the metastatic immune microenvironment46
Integrated analysis of single-cell and bulk RNA sequencing data reveals a myeloid cell-related regulon predicting neoadjuvant immunotherapy response across cancers46
Reframing ME/CFS: toward a unified mechanistic model of chronic post-infectious diseases46
Nuclear receptor Nr1d1 links sleep deprivation to intestinal homeostasis via microbiota-derived taurine46
Exploring epigenome-proteome interactions underlying post-surgical progression of non-functioning pituitary adenomas using hypernetwork modelling46
Integrated lipidomics and network pharmacology analysis to reveal the mechanisms of berberine in the treatment of hyperlipidemia46
Influence of OCT2 gene variants on metformin efficacy in type 2 diabetes: insights into pharmacogenomics and drug interactions46
Low-dose MyoAAV 2A-mediated delivery of engineered micro-utrophin achieves pan- muscle tissue distribution with elevated muscle function in Duchenne muscular dystrophy45
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