OOIR: Observatory of International Research

Papers

(The median citation count of Biological Procedures Online is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Heregulin Activity Assays for Residual Testing of Cell Therapy Products	68
Molecular Characterization of Lineage-IV Peste Des Petits Ruminants Virus and the Development of In-House Indirect Enzyme-Linked Immunosorbent Assay (IELISA) for its Rapid Detection”	61
Correction: Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study	58
Standardized Pre-clinical Surgical Animal Model Protocol to Investigate the Cellular and Molecular Mechanisms of Ischemic Flap Healing	49
Mechanisms of T-cell Depletion in Tumors and Advances in Clinical Research	31
Assessment of MALDI-TOF MS for Arthropod Identification Based on Exuviae Spectra Analysis	28
Investigating the Anti-inflammatory Effect of Quinoline Derivative: N1-(5-methyl-5H-indolo[2,3-b]quinolin-11-yl)benzene-1,4-diamine Hydrochloride Loaded Soluble Starch Nanoparticles Against Methotrexa	28
D-allose Inhibits TLR4/PI3K/AKT Signaling to Attenuate Neuroinflammation and Neuronal Apoptosis by Inhibiting Gal-3 Following Ischemic Stroke	27
Circ-ABCB10 knockdown inhibits the malignant progression of cervical cancer through microRNA-128-3p/ZEB1 axis	23
Isolation and characterization of apical papilla cells from root end of human third molar and their differentiation into cementoblast cells: an in vitro study	19
The untargeted urine volatilome for biomedical applications: methodology and volatilome database	17
A high-throughput screening system for SARS-CoV-2 entry inhibition, syncytia formation and cell toxicity	15
Establishment and Fractionation of Metastatic Axillary Lymph Node Cell Suspension for Determination of Protein Expression Levels of Nuclear cFOS and Cytosolic TGFβ1 from Breast Cancer Patients	15
Trastuzumab-resistant breast cancer cells-derived tumor xenograft models exhibit distinct sensitivity to lapatinib treatment in vivo	14
TACE responser NDRG1 acts as a guardian against ferroptosis to drive tumorgenesis and metastasis in HCC	14
A novel telomere-associated genes signature for the prediction of prognosis and treatment responsiveness of hepatocellular carcinoma	13
EAF2 Downregulation Recruits Tumor-associated Macrophages in Prostate Cancer through Upregulation of MIF	13
Impact of HER2 Expression on the Prognosis of Muscle-Invasive Bladder Cancer Patients Treated with Bladder-Preservation Comprehensive Therapy	13
Combating the menace of antimicrobial resistance in Africa: a review on stewardship, surveillance and diagnostic strategies	13
Comprehensive Insights into APOBEC Mutations in Thyroid Cancer: Prognostic and Therapeutic Discoveries	13
The Impact of Blood and Urine Biomarkers on Age-Related Macular Degeneration: Insights from Mendelian Randomization and Cross-sectional Study from NHANES	13
A 3D human co-culture to model neuron-astrocyte interactions in tauopathies	12
Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production	11
Recent Advances in mRNA-Based Vaccines Against Several Hepatitis Viruses	11
Eicosapentaenoic acid loaded silica nanoemulsion attenuates hepatic inflammation through the enhancement of cell membrane components	11

Chang-Wei-Qing Combined with PD-1 Inhibitor Alleviates Colitis-Associated Colorectal Tumorigenesis by Modulating the Gut Microbiota and Restoring Intestinal Barrier	11
Immune-Related Long Non-coding RNA Constructs a Prognostic Signature of Ovarian Cancer	10
Comparison of two protocols for the generation of iPSC-derived human astrocytes	10
Correction: Analysis and Interpretation of Metagenomics Data: An Approach	9
Genetic engineering of novel yellow color african violet (Saintpaulia ionantha) produced by accumulation of Aureusidin 6-O-glucoside	9
The Role of Cell Organelles in Rheumatoid Arthritis with Focus on Exosomes	8
A novel 7 RNA-based signature for prediction of prognosis and therapeutic responses of wild-type BRAF cutaneous melanoma	8
Decoding the Virtual 2D Map of the Chloroplast Proteomes	8
Analysis and Interpretation of metagenomics data: an approach	8
Establishing a rabbit model with massive supraspinatus tendon defect for investigating scaffold-assisted tendon repair	8
Mechanisms of drug resistance in hepatocellular carcinoma	7
Biomarkers and ImmuneScores in lung cancer: predictive insights for immunotherapy and combination treatment strategies	7
Correction: Methyl β-Cyclodextrin-sperm-mediated gene editing (MBCD-SMGE): a simple and efficient method for targeted mutant mouse production	7
Photothermal Hyperthermia Suppresses Liver Tumor Growth Via Hippo Signaling Pathway-Dependent Inhibition of Cell Proliferation and Induction of Apoptosis	7
Exploring the Mechanism of Canmei Formula in Preventing and Treating Recurrence of Colorectal Adenoma Based on Data Mining and Algorithm Prediction	7
Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor	6
Short-term Outcome of RPVBT Combined with Chemotherapy for Patients with Single, < 3 cm, T2 Stage Bladder cancer	6
Macrophage-Derived MMP-9 and MMP-2 are Closely Related to the Rupture of the Fibrous Capsule of Hepatocellular Carcinoma Leading to Tumor Invasion	6
BPTF in bone marrow provides a potential progression biomarker regulated by TFAP4 through the PI3K/AKT pathway in neuroblastoma	6
Extracellular Vesicles for Drug Delivery in Cancer Treatment	5
KDELR2-KIF20A axis facilitates bladder cancer growth and metastasis by enhancing Golgi-mediated secretion	5
Mitigating Tumor Recurrence through Mitochondrial Metabolism Inhibition: A Novel NIR Laser-Induced Therapeutic Strategy	5
Metabolic and Immunological Implications of MME+CAF-Mediated Hypoxia Signaling in Pancreatic Cancer Progression: Therapeutic Insights and Translational Opportunities	5
Establishment of a mouse lung cancer organoid model and its applications for therapeutic screening	5
Celebrating World Cancer Day: Innovative Biological Approaches to Cancer and their Alignment with Sustainable Development Goals (SDGs)	4
Genetic Analysis of Platelet-Related Genes in Hepatocellular Carcinoma Reveals a Novel Prognostic Signature and Determines PRKCD as the Potential Molecular Bridge	4
Heterogeneity and efficacy of immunotherapy in multiple cancer: insights from a meta-analysis	4
Breaking the Mucin Barrier: A New Affinity Chromatography-Mass Spectrometry Approach to Unveil Potential Cell Markers and Pathways Altered in Pseudomyxoma Peritonei	4
PMS2 amplification contributes brain metastasis from lung cancer	4
RAD6 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma by Regulating Histone Ubiquitination of CCNB1	4
OTUB2 Regulates YAP1/TAZ to Promotes the Progression of Esophageal Squamous Cell Carcinoma	4
Comparing the Proteomic Profiles of Extracellular Vesicles Isolated using Different Methods from Long-term Stored Plasma Samples	4
Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy	4
A novel method to efficiently differentiate human osteoclasts from blood-derived monocytes	3
Employing Raman Spectroscopy and Machine Learning for the Identification of Breast Cancer	3
YTHDF2 exerts tumor-suppressor roles in gastric cancer via up-regulating PPP2CA independently of m6A modification	3
Efficient and scalable gene delivery method with easily generated cationic carbon dots	3
Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells	3
A comprehensive prognostic and immune analysis of enhancer RNA identifies IGFBP7-AS1 as a novel prognostic biomarker in Uterine Corpus Endometrial Carcinoma	3
Identification of exosome protein panels as predictive biomarkers for non-small cell lung cancer	3
Negative Regulation of Cell Adhesion as a Driver of Brain Metastasis in NSCLC Patients with EGFR Amplification	3
Deep learning classification of uveal melanoma based on histopathological images and identification of a novel indicator for prognosis of patients	3
Construction of a circRNA-miRNA-mRNA Regulatory Network for the Immune Regulation of Lung Adenocarcinoma	2
Integrating Omics and CRISPR Technology for Identification and Verification of Genomic Safe Harbor Loci in the Chicken Genome	2
The role of three-dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human adipose-deriv	2
Screening of Natural Compounds for CYP11A1 Stimulation Against Cell Renal Cell Carcinoma	2
Network pharmacology and experimental verification in vivo reveal the mechanism of Zhushao Granules against ulcerative colitis	2
FNDC5 and ACOX1 as Biomarkers of Peroxisomal Activity with Contrast Outcomes in Colon Adenocarcinoma	2
Correction: The role of three‑dimensional scaffolds based on polyglycerol sebacate/ polycaprolactone/ gelatin in the presence of Nanohydroxyapatite in promoting chondrogenic differentiation of human a	2
Protocol for Evaluating In Vivo the Activation of the P2RX7 Immunomodulator	2

Circ_0003570 Suppresses the progression of hepatocellular carcinoma through miR-182-5p/STARD13 regulatory axis	2
Photodynamic Therapy: A Novel Approach for Head and Neck Cancer Treatment with Focusing on Oral Cavity	2
Mesenchymal stem cells: A comprehensive methods for odontoblastic induction	2