OOIR: Observatory of International Research

Papers

(The TQCC of IUBMB Life is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Issue Information	117
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Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	62
Discovery and Validation of a New Biomarker Integrating Ferroptosis and Glycolysis‐Related Genes in Bladder Cancer	57
Issue Information	46
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	34
Central nervous system cholesterol metabolism in health and disease	33
Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	32
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	29
Mitochondrial protein and organelle quality control—Lessons from budding yeast	29
Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	28
Issue Information	26
The roles of proteases in prostate cancer	26
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Next‐Generation Nanomaterials in Biology: From Tissue Regeneration to Targeted Cancer Therapy	24
Modulation of PPAR‐α and PPAR‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling	24
The role of the proteasome in mitochondrial protein quality control	23
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	22
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	22
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	21
Optimization of the chromium (Cr⁺⁶) reduction from waterways using chemically and bacterially treated agro‐waste	21
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	20
Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	20
Cholesterol‐dependent cytolysins: The outstanding questions	18
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	18

N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	17
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	17
RETRACTION : Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	17
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	16
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	16
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	15
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	14
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	13
Eddy Fischer—Renaissance scientist and bon viveur	13
Issue Information	13
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Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	13
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	13
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Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	13
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Hypoxia‐Inducible Factors as Guardians of Cancer Stem Cell Fate: Implications for Novel Therapies	12
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Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	12
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	12
Euryhaline Black Yeasts From the Arabian Gulf: Descriptions of Salinomyces qatarensis sp. nov. and Hortaea werneckii Genotypic Variations	12
Deciphering the Angiogenic Switch: The Role of miRNAs in Breast Cancer	12
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	12
Issue Information	11
Correction to “Tissue Factor Driven Coagulation and Inflammation in Lung Injury: Insights From In Vitro and In Vivo Models”	10
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	10
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	10
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	10
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	10
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	10
Role of extracellular vesicles in mitochondrial eye diseases	10
Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV ‐2 targeting main protease and papain‐like protease	10
Issue Information	10
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Issue Highlights	9
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Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	9
Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	9
Issue Information	9
Correction to “Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3”	9
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	9
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MIA3 in Coronary Artery Disease ( CAD ): An In‐Depth Review of Its	9
17‐Oxo‐DHA Potentiates Macrophage Efferocytosis via Nrf2/HO‐1‐Mediated Biosynthesis of Specialized Pro‐Resolving Mediators	9
The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	9
RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	9
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
RetroGREAT signaling: The lessons we learn from yeast	8
Genomic features of lichen‐associated black fungi	8

Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8
Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
CYP17A1 Locus: Regulatory Mechanisms and Clinical Associations With Cardiovascular Disease and Metabolic Syndrome	8
A standardised nomenclature for long non‐coding RNAs	7
Cover Image	7
Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	7
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Integrated Analysis of Single‐Cell and Bulk RNA Sequencing Data Reveals Cellular Senescence‐Related Signatures Predicting New Potential Therapeutic Drugs in Hepatic Ischemia‐Reperfusion Inj	7
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Gastric Cancer Cell‐Derived Exosomes Induce Macrophage M2 Polarization by Delivering circSMARCC1 t	7
All‐Trans Retinoic Acid as a Predictor and Therapeutic Agent for Vascular Calcification	7
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	7
EXPRESSION OF CONCERN : Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	7
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	7
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	7
Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
Analysis of miRNA Expression Profiles in High Cholesterol Diet‐Induced MASH Progression: Potential Effect of α‐Tocopherol	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	6
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	6
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase‐3 and NFκB Signaling	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	6
1,25(OH)₂D₃ inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	6
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	6
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Nano‐therapeutics: The upcoming nanomedicine to treat cancer	6
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Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes	5
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N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
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ADAM15 Is a Potential Biomarker for Pan‐Cancer Prognosis and Immunotherapy: Validation in HCC and	5
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The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	5
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	5
Issue Information	5