OOIR: Observatory of International Research

Papers

(The TQCC of IUBMB Life is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Issue Information	89
Issue Information	50
	49
The role of the proteasome in mitochondrial protein quality control	43
Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow	40
SNHG14 promotes triple‐negative breast cancer cell proliferation, invasion, and chemoresistance by regulating the ERK/MAPK signaling pathway	38
Thiourea derivatives inhibit key diabetes‐associated enzymes and advanced glycation end‐product formation as a treatment for diabetes mellitus	32
Mitochondrial protein and organelle quality control—Lessons from budding yeast	30
Modulation of PPAR‐α and PPAR‐γ Influences Cardiomyocyte Growth and Cardiac Remodeling	29
Integrated multi‐omics and machine learning reveal a gefitinib resistance signature for prognosis and treatment response in lung adenocarcinoma	26
Issue Information	24
Irisin alleviates the pyroptosis of β cells in T2DM by inhibiting NLRP3 inflammasome through regulating miR‐19b‐3p/SOCS3/STAT3 axis mediated auto	23
Central nervous system cholesterol metabolism in health and disease	23
Serum/glucocorticoid‐regulated kinase 1‐targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activat	22
Anti‐inflammatory effects of sodium‐glucose cotransporter‐2 inhibitors in COVID‐19	22
Issue Information	22
Discovery and Validation of a New Biomarker Integrating Ferroptosis and Glycolysis‐Related Genes in Bladder Cancer	21
Preface to IUBMB life special issue on protein phosphorylation dedicated to Eddy Fischer	20
The roles of proteases in prostate cancer	20
miR‐203a—A multifaceted regulator modulating cancer hallmarks and therapy response	19
Combined doxorubicin and arctigenin treatment induce cell cycle arrest‐associated cell death by promoting doxorubicin uptake in doxorubicin‐resistant breast cancer cells	19
	19
RETRACTION: Nutritional Flavonoids Modulate Estrogen Receptor α Signaling	18
Low expression of PCK2 in breast tumors contributes to better prognosis by inducing senescence of cancer cells	18
Potential COVID‐19 remedies from repurposed drugs and herbal small RNAs	17

MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer	17
Optimization of the chromium (Cr⁺⁶) reduction from waterways using chemically and bacterially treated agro‐waste	17
Cholesterol‐dependent cytolysins: The outstanding questions	16
Kaempferide triggers apoptosis and paraptosis in pancreatic tumor cells by modulating the ROS production, SHP‐1 expression, and the STAT3 pathway	16
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK‐3β pathway and metalloproteases	16
Circular RNAs in chemotherapy resistance of lung cancer and their potential therapeutic application	16
N6‐methyladenosine regulators are potential prognostic biomarkers for multiple myeloma	16
	15
Nicotinamide mononucleotide alters body composition and ameliorates metabolic disorders induced by a high‐fat diet	15
Non‐coding RNA regulatory networks in post‐transcriptional regulation of VEGFA in cancer	15
Issue Information	15
Underlying selection for the diversity of spike protein sequences of SARS‐CoV‐2	15
Issue Information	14
Eddy Fischer—Renaissance scientist and bon viveur	14
2‐Deoxy‐D‐glucose simultaneously targets glycolysis and Wnt/β‐catenin signaling to inhibit cervical cancer progression	14
Issue Highlights	14
CD38/cADPR‐mediated calcium signaling in a human myometrial smooth muscle cell line, PHM1	14
Dynamic association of flavin cofactors to regulate flavoprotein function	13
Enhanced HER2 status detection in breast and gastric cancers using surrogate DNA methylation markers	13
Knockdown of ST6Gal‐I expression in human hepatocellular carcinoma cells inhibits their exosome‐mediated proliferation‐ and migration‐promoting effects	13
Overexpression of RGPR‐p117 reveals anticancer effects by regulating multiple signaling pathways in bone metastatic human breast cancer MDA‐MB‐231 cells	13
Issue Highlights	12
Central nervous system organoids for modeling neurodegenerative diseases	12
Issue Information	12
Adverse fetal and neonatal impact of war conflicts during pregnancy: A systematic review	12
Mechanisms of epigenetic regulation of transcription by lncRNAs in plants	12
Particulate matters 2.5 induce tumor progression in lung cancer by increasing the activity of hnRNPA2B1 resulting in retarding mRNA decay of oxidative phosphorylation	11
Euryhaline Black Yeasts From the Arabian Gulf: Descriptions of Salinomyces qatarensis sp. nov. and Hortaea werneckii Genotypic Variations	11
Mitochondrial respiratory supercomplexes of the yeast Saccharomyces cerevisiae	11
Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells	11
Lectins CGL and MTL, representatives of mytilectin family, exhibit different antiproliferative activity in Burkitt's lymphoma cells	11
Experimental evolution of extremotolerant and extremophilic fungi under osmotic stress	11
Issue Information	11
Role of extracellular vesicles in mitochondrial eye diseases	10
Cover Image	10
Unraveling antiviral efficacy of multifunctional immunomodulatory triterpenoids against SARS‐COV‐2 targeting main protease and papain‐like protease	9
Correction to “Upstream Transcription Factor 1 Suppresses Laryngeal Squamous Cell Carcinoma Progression Through Transcriptional Activation of Junctional Adhesion Molecule 3”	9
Neuroprotection and mechanisms of ginsenosides in nervous system diseases: Progress and perspectives	9
RNA processing and degradation mechanisms shaping the mitochondrial transcriptome of budding yeasts	9
Issue Information	9
Issue Information	9
17‐Oxo‐DHA Potentiates Macrophage Efferocytosis via Nrf2/HO‐1‐Mediated Biosynthesis of Specialized Pro‐Resolving Mediators	9
Erythroid spectrin binding modulates peroxidase and catalase activity of heme proteins	9
Issue Highlights	9
The up‐regulation of RIPK3 mediated by ac4C modification promotes oxidative stress‐induced granulosa cell senescence by inhibiting the Nrf2/HO‐1 pathway	9
Imperative connotation of SODs in cancer: Emerging targets and multifactorial role of action	9
Issue Information	8
	8
Parecoxib inhibits tumorigenesis and angiogenesis in hepatocellular carcinoma through ERK–VEGF/MMPs signaling pathway	8
Ferulic acid ameliorates acetaminophen‐induced acute liver injury by promoting AMPK‐mediated protective autophagy	8

A standardised nomenclature for long non‐coding RNAs	8
	8
Depletion of macrophages and osteoclast precursors mitigates iron overload‐mediated bone loss	8
Early steps in the biogenesis of mitochondrially encoded oxidative phosphorylation subunits	8
Desaturases: Structural and mechanistic insights into the biosynthesis of unsaturated fatty acids	8
Greater TIMP‐1 protein levels and neointimal formation represent sex‐dependent cellular events limiting aortic vessel expansion in female rats	8
Pseudoexfoliation syndrome: The critical role of the extracellular matrix in pathogenesis and treatment	8
Corrigendum	8
Genomic features of lichen‐associated black fungi	8
RetroGREAT signaling: The lessons we learn from yeast	8
Integrated Analysis of Single‐Cell and Bulk RNA Sequencing Data Reveals Cellular Senescence‐Related Signatures Predicting New Potential Therapeutic Drugs in Hepatic Ischemia‐Reperfusion Inj	8
EXPRESSION OF CONCERN: Laccase Treatment Impairs Bisphenol A‐Induced Cancer Cell Proliferation Affecting Estrogen Receptor α‐Dependent Rapid Signals	8
	7
Analysis of miRNA Expression Profiles in High Cholesterol Diet‐Induced MASH Progression: Potential Effect of α‐Tocopherol	7
CRYAB is upregulated and predicts clinical prognosis in kidney renal clear cell carcinoma	7
Variability in the levels of exosomal miRNAs among human subjects could be explained by differential interactions of exosomes with the endothelium	7
	7
Cover Image	7
Correction to “Caffeic acid phenethyl ester synergistically enhances docetaxel and paclitaxel cytotoxicity in prostate cancer cells”	7
Cover Image	7
The ins and outs of the flavin mononucleotide cofactor of respiratory complex I	7
Structure–function relationships between the human bitter taste receptor TAS2R38 and propylthiouracil: An in‐silico investigation	7
Stem cell genes in atheromatosis: The role of Klotho, HIF1α, OCT4, and BMP4	6
Issue Information	6
Nano‐therapeutics: The upcoming nanomedicine to treat cancer	6
The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG‐related disorders	6
Issue Information	6
Neuromelanins in brain aging and Parkinson's disease: synthesis, structure, neuroinflammatory, and neurodegenerative role	6
Correction to “Astrakurkurone, a Sesquiterpenoid From Wild Edible Mushroom, Targets Liver Cancer Cells by Modulating Bcl‐2 Family Proteins”	6
Pore‐forming aegerolysin and MACPF proteins in extremotolerant or extremophilic fungi	6
Golgi quality control and autophagy	6
Il‐6 and UGT1A1 variations may related to furosemide resistance in heart failure patients	6
1,25(OH)₂D₃ inhibits Lewis lung cancer cell migration via NHE1‐sensitive metabolic reprograming	6
KGF secreted from HSCs activates PAK4/BMI1, promotes HCC stemness through PI3K/AKT pathway	6
The Synergic Inhibition of Wilforlide A With Cisplatin in Lung Cancer Is Mediated Through Caspase‐3 and NFκB Signaling	6
The beneficial effect of synbiotics consumption on Alzheimer's disease mouse model via reducing local and systemic inflammation	6
The role of SF3B1 and NOTCH1 in the pathogenesis of leukemia	6
FOXC2‐induced circCASK aggravates colorectal cancer progression by upregulating SIX1 expression	6
N‐acetylneuraminic acid modulates SQSTM1/p62 sialyation‐mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice	5
Issue Information	5
Tyrosine and Phenylalanine Activate Neuronal DNA Repair but Exhibit Opposing Effects on Global Transcription and Adult Female Mice Are Resilient to TyrRS/YARS1 Depleti	5
Analyzing the role of ferroptosis in ribosome‐related bone marrow failure disorders: From pathophysiology to potential pharmacological exploitation	5
Cover Image	5
Therapeutic Potential of Translational Readthrough at Disease‐Associated Premature Termination Codons From Tumor Suppressor Genes	5
Issue Information	5
Correction to “LncRNA RAD51‐AS1/miR‐29b/c‐3p/NDRG2 crosstalk repressed proliferation, invasion and glycolysis of colorectal cancer”	5
Issue Information	5
Cofactors and pathogens: Flavin mononucleotide and flavin adenine dinucleotide (FAD) biosynthesis by the FAD synthase from Brucella ovis	5
The multifaceted antineoplastic role of pyrimethamine against human malignancies	5
	5
Correction to “Retraction”	5