American Journal of Physiology-Renal Physiology

Article	Citations
First Author Highlights	69
First Author Highlights	56
First Author Spotlight	51
HMGB1 drives T-cell activation in hypertensive males and females	51
Protective effect of d-alanine against acute kidney injury	35
Beast of (renal) burden? Bst1-expressing neutrophils in kidney injury	33
Expression and localization of HSD17B13 along mouse urinary tract	33
Urine concentration impairment in sickle cell anemia: genuine nephrogenic diabetes insipidus or osmotic diuresis?	31
Could an intrarenal Cori cycle participate in the urinary concentrating mechanism?	30
First Author Spotlight	29
The injury-induced transcription factor SOX9 alters the expression of LBR, HMGA2, and HIPK3 in the human kidney	29
Sparsentan ameliorates glomerular hypercellularity and inflammatory-gene networks induced by IgA1-IgG immune complexes in a mouse model of IgA nephropathy	29
Stratification of neurogenic bladder risk in spina bifida using the urinary peptidome	28
YAP promotes AP-1 expression in tubular epithelial cells in the kidney	28
First Author Highlights	27
Consensus draft of the native mouse podocyte-ome	26
First Author Highlights	26
Effects of SGLT2 inhibitor and dietary NaCl on glomerular hemodynamics assessed by micropuncture in diabetic rats	25
First Author Highlights	25
Mitochondrial dysfunction in the pathophysiology of renal diseases	24
MFSD12 depletion reduces cystine accumulation without improvement in proximal tubular function in experimental models for cystinosis	24
Handling the sugar rush: the role of the renal proximal tubule	24
Salt-sensitive trait of normotensive individuals is associated with altered autonomous cardiac regulation: a randomized controlled intervention study	24
C-terminal fragment of fibroblast growth factor 23 improves heart function in murine models of high intact fibroblast growth factor 23	23
Raising serum uric acid with a uricase inhibitor worsens PKD in rat and mouse models	23

Rusting from the inside: kidney-specific ferroportin deficiency and associated iron overload dictate susceptibility to acute kidney injury and fibrosis	21
Farnesoid X receptor prevents neutrophil extracellular traps via reduced sphingosine-1-phosphate in chronic kidney disease	21
Membranous translocation of murine double minute 2 promotes the increased renal tubular immunogenicity in ischemia-reperfusion-induced acute kidney injury	20
Liver and spleen predominantly mediate calciprotein particle clearance in a rat model of chronic kidney disease	20
miR-199a-5p aggravates renal ischemia-reperfusion and transplant injury by targeting AKAP1 to disrupt mitochondrial dynamics	20
Quantitative phenotyping of Nphs1 knockout mice as a prerequisite for gene replacement studies	20
Paradoxes in magnesium transport in type 1 Bartter’s syndrome and Gitelman’s syndrome: a modeling analysis	20
Role of the CDKL1-SOX11 signaling axis in acute kidney injury	19
Interleukin-6 blockade reduces salt-induced cardiac inflammation and fibrosis in subtotal nephrectomized mice	19
Benzamil-mediated urine alkalization is caused by the inhibition of H+-K+-ATPases	19
Altered kidney distribution and loss of ACE2 into the urine in acute kidney injury	19
N-methyl-d-aspartate receptor hyperfunction contributes to d-serine-mediated renal insufficiency	19
Oxysterol-binding protein-like 7 deficiency leads to ER stress-mediated apoptosis in podocytes and proteinuria	19
Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway	19
Deletion of Cdh16 Ksp-cadherin leads to a developmental delay in the ability to maximally concentrate urine in mouse	18
Renal claudin-14 expression is not required for regulating Mg2+ balance in mice	18
Multiomic identification of factors associated with progression to cystic kidney disease in mice with nephron Ift88 disruption	18
The Janus view: dual roles for hypoxia-inducible factor in renal repair after acute kidney injury	18
Actin-related protein 2/3 complex plays a critical role in the aquaporin-2 exocytotic pathway	18
Targeting AT2 receptors in renal disease	18
Small hairpin inhibitory RNA delivery in the metanephric organ culture identifies long noncoding RNA Pvt1 as a modulator of cyst growth	18
CB2 cannabinoid receptor agonist selectively inhibits the mechanosensitivity of mucosal afferents in the guinea pig bladder	18
Rapid development of vasopressin resistance in dietary K+ deficiency	18
HIF-1α is transcriptionally regulated by NF-κB in acute kidney injury	18
Differential localization patterns of claudin 10, 16, and 19 in human, mouse, and rat renal tubular epithelia	18
Impact of bedding on Dahl salt-sensitive hypertension and renal damage	17
The transcription factor Foxi1 promotes expression of V-ATPase and Gpr116 in M-1 cells	17
Expression of leptin receptor in renal tubules is sparse but implicated in leptin-dependent kidney gene expression and function	17
Angiotensin (1–7) protects against renal ischemia-reperfusion injury via regulating expression of NRF2 and microRNAs in Fisher 344 rats	17
Intact prostaglandin signaling through EP2 and EP4 receptors in stromal progenitor cells is required for normal development of the renal cortex in mice	17
Persistence and expansion of hypoxia detected by pimonidazole adduct immunostaining during progression of diabetic nephropathy in diabetic mice	17
Wilms’ tumor gene 1: lessons from the interface between kidney development and cancer	17
A mathematical model of the rat kidney. IV. Whole kidney response to hyperkalemia	17
Caught in the crossfire: cancer, cisplatin therapy, and kidney injury	17
Loss of endothelial glucocorticoid receptor accelerates organ fibrosis in db/db mice	17
Accuracy and processing time of kidney volume measurement methods in rodents polycystic kidney disease models: superiority of semiautomated kidney segmentation	16
Elevated luminal inorganic phosphate suppresses intestinal Zn absorption in 5/6 nephrectomized rats	16
The apical 70-pS K+ channel in the thick ascending limb of Henle’s loop is a large-conductance Na+-and Cl–-activated, KNa1.1-like, channel	16
Peripheral dopamine suppression and elevated cystatin C in early diabetic nephropathy in spontaneously diabetic rats	16
Distinct developmental reprogramming footprint of macrophages during acute kidney injury across species	16
Male Akita mice develop signs of bladder underactivity independent of NLRP3 as a result of a decrease in neurotransmitter release from efferent neurons	15
Chronic infusion of the tryptophan metabolite kynurenine increases mean arterial pressure in male Sprague-Dawley rats	15
Tips on navigating the first year of graduate school for individuals from historically excluded backgrounds	15
“Hi, how can i help you?”: embracing artificial intelligence in kidney research	15
Store-operated Ca2+ entry inhibition ameliorates high glucose and ANG II-induced podocyte apoptosis and mitochondrial damage	15
Role of the SLC22A17/lipocalin-2 receptor in renal endocytosis of proteins/metalloproteins: a focus on iron- and cadmium-binding proteins	14
TRPV4 expression in the renal tubule is necessary for maintaining whole body K+ homeostasis	14
Generation of Atp6v1g3-Cre mice for investigation of intercalated cells and the collecting duct	14
Pretreatment with a novel Toll-like receptor 4 agonist attenuates renal ischemia-reperfusion injury	14
Chronic treatment with IL-25 increases renal M2 macrophages and reduces renal injury in obese Dahl salt-sensitive rats during the prepubescent stage	14

Call for Papers: Exercise and the kidneys in health and disease	14
Corrigendum for Hamdan and Robinson, volume 321, 2021, p. F121–F134	13
Image analysis techniques to map pyramids, pyramid structure, glomerular distribution, and pathology in the intact human kidney from 3-D MRI	13
Corrigendum for Jang et al., volume 326, 2024, p. F69	13
Promises and challenges of miRNA therapeutics	13
Guidelines on antibody use in physiology research	13
Perinatal asphyxia leads to acute kidney damage and increased renal susceptibility in adulthood	12
Endothelial mechanical stretch regulates the immunological synapse interface of renal endothelial cells in a sex-dependent manner	12
Bayesian mapping of protein kinases to vasopressin-regulated phosphorylation sites in renal collecting duct	12
Podocyte endowment and the impact of adult body size on kidney health	12
SGLT2 inhibition effect on salt-induced hypertension, RAAS, and Na+ transport in Dahl SS rats	12
Cognate antigen-independent differentiation of resident memory T cells in chronic kidney disease	11
Glycerol-3-phosphate contributes to the increase in FGF23 production in chronic kidney disease	11
Endothelial cells: potential novel regulators of renal inflammation	11
Lack of renoprotective effects by long-term PCSK9 and SGLT2 inhibition using alirocumab and empagliflozin in obese ZSF1 rats	11
Modulation of blood pressure by dietary potassium and sodium: sex differences and modeling analysis	11
Podocyte-specific silencing of acid sphingomyelinase gene to abrogate hyperhomocysteinemia-induced NLRP3 inflammasome activation and glomerular inflammation	11
“Idiopathic” minimal change nephrotic syndrome: a podocyte mystery nears the end	11
Ribosomal s6 kinase is a mediator of aquaporin-2 S256 phosphorylation and membrane accumulation after EGFR inhibition with erlotinib	11
Transcriptomics of SGLT2-positive early proximal tubule segments in mice: response to type 1 diabetes, SGLT1/2 inhibition, or GLP1 receptor agonism	11
Autophagy and mitophagy: physiological implications in kidney inflammation and diseases	11
Caspase-3-dependent peritubular capillary dysfunction is pivotal for the transition from acute to chronic kidney disease after acute ischemia-reperfusion injury	11
Sex differences in sympathetic activity and pulse wave velocity in adults with chronic kidney disease	11
Looking below the surface: using intravital imaging to decipher inflammatory renal disease and renal cell injury	11
Soluble (pro)renin receptor as a novel regulator of renal medullary Na+ reabsorption	11
First Author Highlights	10
First Author Spotlight	10
First Author Spotlight	10
First Author Highlights	10
First Author Highlights	10
Circulating extracellular vesicles of patients with steroid-sensitive nephrotic syndrome have higher RAC1 and induce recapitulation of nephrotic syndrome phenotype in podocytes	10
First Author Highlights	10
First Author Highlights	10
Perspective on G protein-coupled receptors in renal physiology	10
Renal macro- and microcirculatory perturbations in acute kidney injury and chronic kidney disease associated with heart failure and cardiac surgery	10
Renal cell markers: lighthouses for managing renal diseases	10
First Author Highlights	10
First Author Spotlight	10
First Author Highlights	10
Flow-dependent transport processes 2024: filtration, absorption, secretion	10
Reply to Bankir: the ever-expanding role of lactate in the kidney	10
Role of the polycystins as mechanosensors of extracellular stiffness	9
Tubular dysfunction impairs renal excretion of pseudouridine in diabetic kidney disease	9
Spns1 is an iron transporter essential for megalin-dependent endocytosis.	9
Macrophage polarization and signaling in diabetic kidney disease: a catalyst for disease progression	9
Exercise for patients with chronic kidney disease: from cells to systems to function	9
The mineralocorticoid receptor in diabetic kidney disease	9
Corrigendum for Park et al., volume 322, 2022, p. F553–F572	9
First Author Spotlight	9
Trimethoprim inhibits renal H+-K+-ATPase in states of K+ depletion	9
The FSGS protein actinin-4 interacts with NKCC2 to regulate thick ascending limb NaCl reabsorption	9
Identification of natriuretic peptide receptor A-related gene expression signatures in podocytes in vivo reveals baseline control of protective pathways	9
Chronic mistimed feeding results in renal fibrosis and disrupted circadian blood pressure rhythms	9
Endogenous activation of peroxisome proliferator-activated receptor-α in proximal tubule cells in counteracting phosphate toxicity	9
A combination of β-hydroxybutyrate and citrate ameliorates disease progression in a rat model of polycystic kidney disease	9
Regulating distal nephron functions and salt sensitivity	9
β2-Adrenergic receptor agonists: a new treatment for diabetic kidney disease?	9
Postoperative acute kidney injury after volatile or intravenous anesthesia: a meta-analysis	9
Lipotoxicity dysregulates the immunoproteasome in podocytes and kidneys in type 2 diabetes	9
Impact of sleep on chronobiology of micturition among healthy older adults	9
Myeloid-specific ferritin light chain deletion does not exacerbate sepsis-associated AKI	9
Inhibition of mTORC2 promotes natriuresis in Dahl salt-sensitive rats via the decrease of NCC and ENaC activity	9
Chronic environmental hypoxia attenuates innate immunity activation and renal injury in two CKD models	9
Differential regulation of autophagy on urine-concentrating capability through modulating the renal AQP2 expression and renin-angiotensin system in mice	9
A novel method for automated crystal visualization and quantification in murine folic acid-induced acute kidney injury	9
Corrigendum for Chen et al., volume 317, 2019, p. F137–F151	9
Therapeutic α-1-microglobulin ameliorates kidney ischemia-reperfusion injury	9
Ultrabright plasmonic fluor nanolabel-enabled detection of a urinary ER stress biomarker in autosomal dominant tubulointerstitial kidney disease	8
Macrophage SPAK deletion limits a low potassium-induced kidney inflammatory program	8
An in vivo protein landscape of the mouse DCT during high dietary K+ or low dietary Na+ intake	8
Expression of lactate dehydrogenase A and B isoforms in the mouse kidney	8
Defining protein expression in the kidney at large scale: from antibody validation to cytometry analysis	8
Amiloride evokes significant natriuresis and weight loss in kidney transplant recipients with and without albuminuria	8
WT1 regulates expression of DNA repair gene Neil3 during nephrogenesis	8
Patterns of differentiation of renin lineage cells during nephrogenesis	8
Mapping kidney tubule diameter ex vivo by diffusion MRI	8
Roles of WNK4 and SPAK in K+-mediated dephosphorylation of the NaCl cotransporter	8
Induction of renal tumor necrosis factor-α and other autacoids and the beneficial effects of hypertonic saline in acute decompensated heart failure	8
Thirty years of the NaCl cotransporter: from cloning to physiology and structure	8
Redox regulation in diabetic kidney disease	8

Is fibroblast growth factor 23 the main culprit for cardiovascular disease in chronic kidney disease?	8
Polygenic genetic variation affecting antibody formation underlies hypertensive renal injury in the stroke-prone spontaneously hypertensive rat	8
Mechanisms of decreased tubular flow-induced nitric oxide in Dahl salt-sensitive rat thick ascending limbs	8
Atavistic behavior of macrophages in the injured kidney	8
Control of ENaC ubiquitination	8
A stressed barrier left behind: stochastic podocyte ablation triggers secondary injury	8
Renal mitochondrial dysfunction in ovine experimental sepsis-associated acute kidney injury	8
Renal, but not platelet or skin, extracellular vesicles decrease oxidative stress, enhance nascent peptide synthesis, and protect from ischemic renal injury	8
The miR-143/145 cluster induced by TGF-β1 suppresses Wilms’ tumor 1 expression in cultured human podocytes	8
Hints for a kidney lactate shuttle and lactomone	8
NK1.1−natural killer T cells upregulate interleukin-17 expression in experimental lupus nephritis	8
Renal NG2-expressing cells have a macrophage-like phenotype and facilitate renal recovery after ischemic injury	7
High-calorie diet results in reversible obesity-related glomerulopathy in adult zebrafish regardless of dietary fat	7
Endothelial cells overexpressing CXCR1/2 are renoprotective in rats with acute kidney injury	7
Essential role of Wtip in mouse development and maintenance of the glomerular filtration barrier	7
COP9 signalosome deletion promotes renal injury and distal convoluted tubule remodeling	7
Acute kidney injury biomarkers and hydration assessments following prolonged mild hypohydration in healthy young adults	7
The Indiana O’Brien Center for Advanced Renal Microscopic Analysis	7
Characterization of a functional V1B vasopressin receptor in the male rat kidney: evidence for cross talk between V1B and V2 receptor signaling pathways	7
Acid-sensing ion channels modulate bladder nociception	7
Adaptive changes in single-nephron GFR, tubular morphology, and transport in a pregnant rat nephron: modeling and analysis	7
Nicorandil protects podocytes via modulation of antioxidative capacity in acute puromycin aminonucleoside-induced nephrosis in rats	7
Metabolomic profiling demonstrates evidence for kidney and urine metabolic dysregulation in a piglet model of cardiac surgery-induced acute kidney injury	7
Diabetes causes NLRP3-dependent barrier dysfunction in mice with detrusor overactivity but not underactivity	7
Renal mass reduction increases the response to exogenous insulin independent of acid-base status or plasma insulin levels in rats	7
Increased SGK1 activity potentiates mineralocorticoid/NaCl-induced kidney injury	7
Kidney physiology: our future is now	7
Splenocyte transfer from hypertensive donors eliminates premenopausal female protection from ANG II-induced hypertension	7
Decreased tubuloglomerular feedback response in high-fat diet-induced obesity	7
A new view of macula densa cell protein synthesis	7
Podocytes are lost from glomeruli before completing apoptosis	7
Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development	7
Elevated renal afferent nerve activity in a rat model of endothelin B receptor deficiency	6
Methylseq, single-nuclei RNAseq, and discovery proteomics identify pathways associated with nephron-deficit CKD in the HSRA rat model	6
Nicotinamide ameliorates podocyte injury and albuminuria in adriamycin-induced nephropathy	6
Mitochondria as mediators of systemic inflammation and organ cross talk in acute kidney injury	6
Loss of sphingosine kinase 2 protects against cisplatin-induced kidney injury	6
Induction of plasmalemmal vesicle-associated protein exacerbates glomerular endothelial injury in thrombotic microangiopathy	6
Mast cell function in prostate inflammation, fibrosis, and smooth muscle cell dysfunction	6
Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing	6
TAZ is important for maintenance of the integrity of podocytes	6
The hypoxia-inducible factor-α prolyl hydroxylase inhibitor FG4592 ameliorates renal fibrosis by inducing the H3K9 demethylase JMJD1A	6
Creatinine clearance is maintained in a range of wet-bulb globe temperatures and work-rest ratios during simulated occupational heat stress	6
Therapeutic effects of a soluble guanylate cyclase activator, BAY 60-2770, on lower urinary tract dysfunction in mice with spinal cord injury	6
Potential of soluble (pro)renin receptor in kidney disease: can it go beyond a biomarker?	6
Novel method for kinetic analysis applied to transport by the uniporter OCT2	6
A brief history of the cortical thick ascending limb: a systems-biology perspective	6
Guidelines for sex-specific considerations to improve rigor in renal research and how we got there	6
KIM-1-mediated anti-inflammatory activity is preserved by MUC1 induction in the proximal tubule during ischemia-reperfusion injury	6
Porcine models of acute kidney injury	6
Activation of branched chain amino acid catabolism protects against nephrotoxic acute kidney injury	6
Metformin ameliorates bladder dysfunction in a rat model of partial bladder outlet obstruction	6
Energy depletion by cell proliferation sensitizes the kidney epithelial cells to injury	6
Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression	6
β2-Adrenergic receptor agonists as a treatment for diabetic kidney disease	6
Pax proteins mediate segment-specific functions in proximal tubule survival and response to ischemic injury	6
Collecting duct water permeability inhibition by EGF is associated with decreased cAMP, PKA activity, and AQP2 phosphorylation at Ser269	6
Pax inhibition: stressing proximal tubule for successful repair	6
Transcription factor HNF1β controls a transcriptional network regulating kidney cell structure and tight junction integrity	6
First Author Spotlight	5
First Author Highlights	5
Inhaled silica nanoparticles cause chronic kidney disease in rats	5
First Author Spotlight	5
Kidney functional reserve and damage biomarkers in subclinical chronic kidney disease and acute kidney injury	5
Functional TFEB activation characterizes multiple models of renal cystic disease and loss of polycystin-1	5
N-acetylcysteine treatment attenuates hemodialysis access-related limb pathophysiology in mice with chronic kidney disease	5
Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice	5
First Author Highlights	5
Kidney hemodynamic function in men and postmenopausal women with type 2 diabetes and preserved kidney function	5
First Author Spotlight	5
IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage	5
SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy	5
First Author Spotlight	5
First Author Highlights	5
Brown-Norway chromosome 1 mitigates the upregulation of proinflammatory pathways in mTAL cells and subsequent age-related CKD in Dahl SS/JrHsdMcwi rats	5
The calcium-sensing receptor has only a parathyroid hormone-dependent role in the acute response of renal phosphate transporters to phosphate intake	5
Transcriptomic signatures of exacerbated progression in leptospirosis subclinical chronic kidney disease with secondary nephrotoxic injury	5
Therapeutic effects of KCC2 chloride transporter activation on detrusor overactivity in mice with spinal cord injury	5
First Author Spotlight	5
First Author Highlights	5
The kidney protects against sepsis by producing systemic uromodulin	5
Less sodium, more potassium, or both: population-wide strategies to prevent hypertension	5
First Author Highlights	5
Single cell versus single nucleus: transcriptome differences in the murine kidney after ischemia-reperfusion injury	5
Is there a role for uric acid in polycystic kidney disease progression?	5
The degree of aortic occlusion in the setting of trauma alters the extent of acute kidney injury associated with mitochondrial preservation	5
C1 inhibitor mitigates peritoneal injury in zymosan-induced peritonitis	5
Kcnma1 alternative splicing in mouse kidney: regulation during development and by dietary K+ intake	4
Mitochondria-derived reactive oxygen species contribute to synergistic interaction of diabetes and hypertension in causing chronic kidney injury	4
Deletion of AT1a receptors selectively in the proximal tubules of the kidney alters the hypotensive and natriuretic response to atrial natriuretic peptide via NPRA/cGMP/NO signal	4
Bladder infection with uropathogenic Escherichia coli increases the excitability of afferent neurons	4
Matrix metalloproteinases in kidney homeostasis and diseases: an update	4
Fasting mimicking diet in diabetic mice partially preserves glomerular endothelial glycocalyx coverage, without changing the diabetic metabolic environment	4
Long-term follow-up of TREK-1 KO mice reveals the development of bladder hypertrophy and impaired bladder smooth muscle contractility with age	4
Predicting sex differences in the effects of diuretics in renal epithelial transport during angiotensin II-induced hypertension	4