OOIR: Observatory of International Research

Papers

(The TQCC of Current Oncology Reports is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Oligometastatic Esophagogastric Cancer: Does It Exist and How Do We Treat It?	141
New Developments in VHL-Associated Neuroendocrine Neoplasms	132
Cardiotoxic Effects Following CAR-T Cell Therapy: A Literature Review	123
ChatGPT in Oncology Diagnosis and Treatment: Applications, Legal and Ethical Challenges	83
Beneath the Surface: The Emerging Role of Ultra-Processed Foods in Obesity-Related Cancer	81
Treatment Following Progression in Metastatic Melanoma: the State of the Art from Scientific Literature to Clinical Need	74
Dealing with Family Conflicts in Decision-making in End-of-Life Care of Advanced Cancer Patients	73
Toxicities from BRAF and MEK Inhibitors: Strategies to Maximize Therapeutic Success	69
Richter’s Transformation	69
Limb Amputations in Cancer: Modern Perspectives, Outcomes, and Alternatives	65
Asparaginase: How to Better Manage Toxicities in Adults	61
New Directions in Treatment of Metastatic or Advanced Pheochromocytomas and Sympathetic Paragangliomas: an American, Contemporary, Pragmatic Approach	51
PEGylated IL-10: Clinical Development in Cancer Immunotherapy, Where to Go?	48
Clonal Hematopoiesis of Indeterminate Potential: Current Understanding and Future Directions	47
Oncolytic Viruses and Cancer Immunotherapy	41
Surgery in the Era of Immunotherapy for Advanced Head and Neck Non-melanoma Skin Cancer	39
Advanced Pancreatic Neuroendocrine Neoplasms: Which Systemic Treatment Should I Start With?	39
What Causes Desmoplastic Reaction in Small Intestinal Neuroendocrine Neoplasms?	37
Addressing Residual Disease in HER2-Positive and Triple-Negative Breast Cancer: What Is Next?	35
BCR/ABL-Positive Chronic Myeloid Leukemia in Children: Current Treatment Approach	33
Cardiotoxicity of Immune Checkpoint Inhibitors	33
Germline Mutations and Ancestry in Prostate Cancer	32
First-Line Treatment of Metastatic Non-Small Cell Lung Cancer in the Elderly	32
New Insights on Tramadol and Immunomodulation	31
Shifting Epidemiology of Hepatocellular Carcinoma in Far Eastern and Southeast Asian Patients: Explanations and Implications	31

Graft-Versus-Host Disease: an Update on Functional Implications and Rehabilitation Interventions	30
NRG1 Fusions: The New Kid on the Block	30
Managing the Risk of Infection in Chronic Lymphocytic Leukemia in the Era of New Therapies	30
Management of Pathologic Node-Positive Prostate Cancer following Radical Prostatectomy	29
Integrating Precision Medicine into the Contemporary Management of Gynecologic Cancers	28
Immunotherapeutic and Targeted Strategies for Managing Brain Metastases from Common Cancer Origins: A State-of-the-Art Review	27
Exploring DESTINY: the Past, Present, and Future of Trastuzumab Deruxtecan	27
Surgical Management of Melanoma: Advances and Updates	26
Current Approaches to Philadelphia Chromosome–Positive B-Cell Lineage Acute Lymphoblastic Leukemia: Role of Tyrosine Kinase Inhibitor and Stem Cell Transplant	26
Management of Upper Tract Urothelial Carcinoma	26
Robotic Surgery for Head and Neck Tumors: What are the Current Applications?	26
Correction to: New Advances in Supportive Care: Chemoprotective Agents as Novel Opportunities in Geriatric Oncology	25
The Role and Impact of Social Media in Cardio-oncology During the COVID-19 Pandemic	25
Statins for the Primary Prevention of Anthracycline Cardiotoxicity: A Comprehensive Review	25
Emerging Role of PARP Inhibitors in Metastatic Prostate Cancer	23
Newly Diagnosed Glioblastoma in Elderly Patients	23
Germline Genetic Testing in Breast Cancer: Systemic Therapy Implications	23
Return to Intended Oncological Therapy: State of the Art and Perspectives	23
The Microbiome’s Influence on Head and Neck Cancers	22
Kidney Cancer Integrative Oncology: Possible Options for Care	22
Correction to: Current Status of Perioperative Therapy in Muscle‑Invasive Bladder Cancer and Future Directions	22
Nectin-4: a Tumor Cell Target and Status of Inhibitor Development	22
Resistance to Poly (ADP-Ribose) Polymerase Inhibitors (PARPi): Mechanisms and Potential to Reverse	22
Antiangiogenic Therapy for Malignant Brain Tumors: Does It Still Matter?	22
Diagnostic and Therapeutic Updates in Leptomeningeal Disease	22
Telemedicine in Cancer Care Beyond the COVID-19 Pandemic: Oncology 2.0?	22
Cardiovascular Effects of Immune Checkpoint Inhibitors: More Than Just Myocarditis	22
Cured or Not? Long-term Outcomes of Immunotherapy Responders. Focus on Melanoma	22
New Treatments for Recurrent Uterine Cancer	21
Rectal Neuroendocrine Neoplasms: Why Is There a Global Variation?	20
Treatment Perspectives for Ovarian Cancer in Europe and the United States: Initial Therapy and Platinum-Sensitive Recurrence after PARP Inhibitors or Bevacizumab Therapy	20
The Value Proposition of Observation Medicine in Managing Acute Oncologic Pain	20
Global Longitudinal Strain Monitoring to Guide Cardioprotective Medications During Anthracycline Treatment	19
Mantle Cell Lymphoma: the Role of Risk-Adapted Therapy and Treatment of Relapsed Disease	19
Functional Outcomes and Quality of Life in Patients with Sinonasal, Nasopharyngeal, and Anterior Skull Base Tumors	19
Molecular Subgroups of Diffuse Large B Cell Lymphoma: Biology and Implications for Clinical Practice	19
Immune Checkpoint Inhibitors in the Aged	19
Quality of Life and Survivorship in Lymphoma	18
Fluoropyrimidine Cardiotoxicity: Incidence, Outcomes, and Safety of Rechallenge	18
Current Management of Refractory Germ Cell Tumors	18
Hairy Cell Leukemia (HCL) and HCL Variant: Updates and Spotlights on Therapeutic Advances	18
The Care of the Leukemic Patients in Times of SARS-CoV-2	17
Changing the Perspective on Fertility Preservation for Women with Metastatic or Advanced Stage Cancer	17
Cardiovascular Toxicities of CAR T-cell Therapy	17
How to Manage Small Intestine (Jejunal and Ileal) Neuroendocrine Neoplasms Presenting with Liver Metastases?	17
Extramammary Paget Disease: a Therapeutic Challenge, for a Rare Entity	17
Current Understanding and Management of Intraductal Carcinoma of the Prostate	17
Enhanced Recovery in Gynecologic Oncology Surgery—State of the Science	17
Management of Central and Peripheral Nervous System Tumors in Patients with Neurofibromatosis	16
Blood–Brain Barrier Disruption for the Treatment of Primary Brain Tumors: Advances in the Past Half-Decade	16

Integrative Oncology Approaches to Supporting Immune Checkpoint Inhibitor Treatment of Solid Tumours	16
Nasal Cavity and Paranasal Sinus Cancer: Diagnosis and Treatment	16
Navigating the Rapidly Evolving Advanced Urothelial Carcinoma Treatment Landscape: Insights from Italian Experts	16
Prostate Cancer, Pathophysiology and Recent Developments in Management: A Narrative Review	16
Incorporation of Palliative Care in Gynecologic Oncology	16
Telehealth Utilization in Neuro-Oncology: Commentary on a Single Institution Experience After the COVID-19 Pandemic	16
Treatment of Metastatic Melanoma in the Elderly	15
Prostate Cancer Immunotherapy—Finally in From the Cold?	15
Molecular Biomarkers in Sinonasal Cancers: New Frontiers in Diagnosis and Treatment	15
Antibiotic Management of Patients with Hematologic Malignancies: From Prophylaxis to Unusual Infections	15
WEE1 Inhibitor: Clinical Development	15
CAR T-Cell Therapy in the Older Person: Indications and Risks	15
Interventions to Reduce Sedentary Behavior in Cancer Patients and Survivors: a Systematic Review	15
Advances in Targeted Therapy for Neurofibromatosis Type 2 (NF2)-Associated Vestibular Schwannomas	15
Fatty Acid Metabolism and Cancer Immunotherapy	15
Brain Prehabilitation for Oncologic Surgery	14
Weight Management for Fertility-Preservation Therapy in Endometrial Cancer: Opportunities and Challenges	14
Cardiovascular Impact of Androgen Deprivation Therapy: from Basic Biology to Clinical Practice	14
Approach to the Older Patient with Acute Myeloid Leukemia	14
Hairy Cell Leukemia: Where Are We in 2023?	14
From Detection to Cure – Emerging Roles for Urinary Tumor DNA (utDNA) in Bladder Cancer	14
Metronomic Chemotherapy in Elderly Patients	14
The Emerging Role of Next-Generation Imaging in Prostate Cancer	14
Immunotherapy in Biliary Tract Cancers: Where Are We?	14
Current Status of Immunotherapy in Management of Small Bowel Neuroendocrine Tumors	14
Start of a New Era: Management of Non-Clear Cell Renal Cell Carcinoma in 2022	13
Interventional Treatment Options for Post-mastectomy Pain	13
Neutropenia and Infection Prophylaxis in Childhood Cancer	13
Targeting The Tumor Microenvironment in Lymphomas: Emerging Biological Insights and Therapeutic Strategies	13
Radiation and Melanoma: Where Are We Now?	13
CDK4/6 inhibitors: The Devil is in the Detail	13
Bystander effect of antibody–drug conjugates: fact or fiction?	13
Management of In-Transit Metastases	13
Measurable Residual Disease in Mantle Cell Lymphoma: The Unbearable Lightness of Being Undetectable	13
Integrative Oncology Approaches to Reduce Recurrence of Disease and Improve Survival	13
Head and Neck Mucosal Melanoma: Where Are We Now?	13
DNA Repair Mechanisms and Therapeutic Targets in Glioma	12
Current Trends and Challenges of Microbiome Research in Prostate Cancer	12
Palliative Care in Pediatric Oncology and Hematopoietic Stem Cell Transplantation	12
The Landscape of Immunotherapy in Advanced NSCLC: Driving Beyond PD-1/PD-L1 Inhibitors (CTLA-4, LAG3, IDO, OX40, TIGIT, Vaccines)	12
Role of CTLA Inhibition in Management of Non-Small Cell Lung Cancer	12
15 Years Old ALK Gene from Birth to Adolescence; Where to in NBL	12
Melanoma in Pediatric and Young Adult Patients	12
Engineered T Cells: CAR T Cell Therapy and Beyond	12
Advances in Diagnosis and Treatment for Leptomeningeal Disease in Melanoma	12
Prolymphocytic Leukaemia: an Update on Biology and Treatment	12
New Tyrosine Kinase Inhibitors for the Treatment of Gastrointestinal Stromal Tumors	12
Interventional Strategies in Cancer-induced Cardiovascular Disease	12
Neutrophil Extracellular Trapping Role in Cancer, Metastases, and Cancer-Related Thrombosis: a Narrative Review of the Current Evidence Base	12
The Role of Cannabinoids in Advancing Cancer Treatment: Insights from Evidence-Based Medicine	11
Correction to: Current Status and Challenges in Rare Genitourinary Cancer Research and Future Directions	11
Correction: Newly Diagnosed Glioblastoma in Elderly Patients	11
Acupuncture for Cancer-Related Anorexia: a Review of the Current Evidence	11
The Difficult Airway in Patients with Cancer	11
Correction to: The Changing Landscape of Lymphoma Associated with HIV Infection	11
Developing a National Study That Integrates the Geriatric Assessment into the Care of Older Patients with Myeloid Malignancies	11
Alternative Lengthening of Telomeres (ALT) in Pancreatic Neuroendocrine Tumors: Ready for Prime-Time in Clinical Practice?	11
Risk Stratification, Screening and Treatment of BRAF/MEK Inhibitors-Associated Cardiotoxicity	11
Novel Clinical Trials and Approaches in the Management of Glioblastoma	11
Telemedicine and Virtual Interventions in Cancer Rehabilitation: Practical Application, Complications and Future Potentials	11
Prevention of Ovarian Cancer: Where are We Now and Where are We Going?	11
Cardiac Effects of BRAF and MEK Inhibitors: Mechanisms and Clinical Management	10
Anti-angiogenesis Revisited: Combination with Immunotherapy in Solid Tumors	10
Extracellular vesicles and their associated miRNAs as potential prognostic biomarkers in chronic lymphocytic leukemia	10
Update on Minimally Invasive Surgical Approaches for Rectal Cancer	10
Emerging Role of Biomarkers in Testicular Germ Cell Tumors	10
Approaches to Non-Muscle-Invasive Bladder Cancer	10
Systematic Reviews and Meta-Analyses of Portal Vein Embolization, Associated Liver Partition and Portal Vein Ligation, and Radiation Lobectomy Outcomes in Hepatocellular Carcinoma Patients	10
Is Myelodysplasia a Consequence of Normal Aging?	10
The Role and Impact of Minimal Residual Disease in NSCLC	10
A Systematic Review and Quality Assessment of Breast Cancer Clinical Practice Guidelines Providing Complementary and Alternative Medicine Recommendations	10
Development of Delivery Systems for Local Administration of Cytokines/Cytokine Gene-Directed Therapeutics: Modern Oncologic Implications	10