OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Therapy is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Retraction Notice to: Risk-Associated Long Noncoding RNA FOXD3-AS1 Inhibits Neuroblastoma Progression by Repressing PARP1-Mediated Activation of CTCF	214
Retraction Notice to: Long Noncoding RNA LINC00673 Is Activated by SP1 and Exerts Oncogenic Properties by Interacting with LSD1 and EZH2 in Gastric Cancer	205
Retraction Notice to: The Pseudogene DUXAP8 Promotes Non-small-cell Lung Cancer Cell Proliferation and Invasion by Epigenetically Silencing EGR1 and RHOB	204
Retraction Notice to: METTL14 Suppresses CRC Progression via Regulating N6-Methyladenosine-Dependent Primary miR-375 Processing	184
lncRNA Linc00173 modulates glucose metabolism and multidrug chemoresistance inSCLC:Potentialmolecular panel for targeted therapy	178
Retraction Notice to: lncRNA RMST Enhances DNMT3 Expression through Interaction with HuR	177
Deficiency of galactosyl-ceramidase in adult oligodendrocytes worsens disease severity during chronic experimental allergic encephalomyelitis	165
The impact of revised regenerative medicine regulations on unapproved gene therapies in Japan	165
Dasatinib-resistant universal CAR-T cells proliferate in the presence of host immune cells and exhibit antitumor activity	159
Response to: DNA transposon mechanisms and pathways of genotoxicity	148
CRISPR-Cas9 as a Trojan horse	137
ATGL regulates renal fibrosis by reprogramming lipid metabolism during the transition from AKI to CKD	136
Controlling intracellular protein delivery, tumor colonization and tissue distribution using flhDC in clinically relevant ΔsseJ Salmonella	131
Inhibition of adenylyl cyclase 8 prevents the upregulation of Orai1 channel, which improves cardiac function after myocardial infarction	129
FOXC1 modulates stem-like cell properties and chemoresistance through hedgehog and EMT signaling in gastric adenocarcinoma	129
Inverted HA-EV immunization elicits stalk-specific influenza immunity and cross-protection in mice	129
Y4 RNA fragment alleviates myocardial injury in heart transplantation via SNRNP200 to enhance IL-10 mRNA splicing	126
Promotion or inhibition? This is a question in gene editing	123
RNA and epigenetic editing: The new frontier in gene and cell therapy	116
The emerging regulatory roles of long non-coding RNAs implicated in cancer metabolism	114
Reversing the path: Mesenchymal-to-mesothelial transition as a novel target in liver fibrosis	112
Call for papers: Exploiting extracellular vesicles as therapeutic agents	112
Retraction Notice to: Role of HCP5-miR-139-RUNX1 Feedback Loop in Regulating Malignant Behavior of Glioma Cells	111
Base editing the synapse: Modeling a complex neurological disorder in non-human primates	111
In this issue	111

In this issue	111
2022 ASGCT Annual Meeting Late-breaking Abstracts	110
ASGCT 27th Annual Meeting Late-Breaking Abstracts	109
Spike mutation resilient scFv76 antibody counteracts SARS-CoV-2 lung damage upon aerosol delivery	103
Accessorizing viral vectors with extracellular vesicles for enhanced performance	100
Heal thyself: The promise of autologous hematopoietic stem cell gene therapy in neurometabolic disorders	98
Mavis Agbandje-McKenna’s lifelong commitment to teaching and research	96
Financial considerations in expanded access policy for gene therapies: A tough nut to crack?	94
The first medical education program on gene and gene-modified cell therapies for Latin America	92
In vivo genome editing for inherited retinal disease: Opportunities and challenges	91
In this issue	87
Rationally designed DNA therapeutics can modulate human TH expression by controlling specific GQ formation in its promoter	86
AAV and hepatitis: Cause or coincidence?	83
IL-1Ra gene transfer potentiates BMP2-mediated bone healing by redirecting osteogenesis toward endochondral ossification	82
Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer	82
A novel regulatory mechanism network mediated by lncRNA TUG1 that induces the impairment of spiral artery remodeling in preeclampsia	81
Systematic comparison of rAAV vectors manufactured using large-scale suspension cultures of Sf9 and HEK293 cells	81
CasRx-based Wnt activation promotes alveolar regeneration while ameliorating pulmonary fibrosis in a mouse model of lung injury	81
Engineering small-molecule and protein drugs for targeting bone tumors	80
Targeting RNA oxidation by ISG20-mediated degradation is a potential therapeutic strategy for acute kidney injury	80
Systemic delivery of antagomirs during blood-brain barrier disruption is disease-modifying in experimental epilepsy	80
The efficacy of COVID-19 vaccines against the B.1.617.2 (delta) variant	79
Advanced gene-editing strategy for epidermolysis bullosa simplex	77
A new immune pathway mediating AAV immune responses	75
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR	74
miRNA discovery to therapy: The field is sufficiently mature to assess the value of miRNA-based therapeutics	74
In this issue	74
Getting the host antiviral machinery back on track: Targeting viral suppressors of RNA interference	74
Novel insights into the ROCK-JAK-STAT signaling pathway in upper respiratory tract infections and neurodegenerative diseases	73
VCAM-targeting lipid platform brings new hope to the treatment of ischemic stroke	73
Anti-microRNA-378a Enhances Wound Healing Process by Upregulating Integrin Beta-3 and Vimentin	73
Large-scale falsification of research papers risks public trust in biomedical sciences	72
Ligand-activated RXFP1 gene therapy ameliorates pressure overload-induced cardiac dysfunction	69
Immune responses to cells and proteins after hematopoietic stem cell gene therapy for inherited diseases: A cause for concern	69
An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ	65
Single-cell data-driven design of armed oncolytic virus to boost cooperative innate-adaptive immunity against cancer	65
Precision spinal gene delivery-induced functional switch in nociceptive neurons reverses neuropathic pain	63
A highly stable human single-domain antibody-drug conjugate exhibits superior penetration and treatment of solid tumors	63
From cortex to medulla: Navigating the thymic landscape of T cell education	63
Immunotherapeutic HCW9218 augments anti-tumor activity of chemotherapy via NK cell-mediated reduction of therapy-induced senescent cells	63
Global challenges in preparedness and response to epidemic infectious diseases	63